TECPR2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TECPR2
Entrez Gene ID	9895
Full Name	tectonin beta-propeller repeat containing 2
Synonyms	KIAA0329,SPG49
General protein information	Preferred Names tectonin beta-propeller repeat containing 2 Names tectonin beta-propeller repeat-containing protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q32.31
Summary	The protein encoded by this gene is a member of the tectonin beta-propeller repeat-containing (TECPR) family, and contains both TECPR and tryptophan-aspartic acid repeat (WD repeat) domains. This gene has been implicated in autophagy, as reduced expression levels of this gene have been associated with impaired autophagy. Recessive mutations in this gene have been associated with a hereditary form of spastic paraparesis (HSP). HSP is characterized by progressive spasticity and paralysis of the legs. There is also some evidence linking mutations in this gene with birdshot chorioretinopathy (BSCR), which results in inflammation of the choroid and retina. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015].
Disorder MIM:	615000
Disorder Html:	Spastic paraplegia 49, autosomal recessive, 615031 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_014844.4	NP_055659.2	tectonin beta-propeller repeat-containing protein 2 isoform 1
NM_001172631.3	NP_001166102.1	tectonin beta-propeller repeat-containing protein 2 isoform 2
NM_001172631.2	NP_001166102.1	tectonin beta-propeller repeat-containing protein 2 isoform 2
NM_014844.5	NP_055659.2	tectonin beta-propeller repeat-containing protein 2 isoform 1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TECPR2	NP_001179619.1
Danio rerio (zebrafish)	tecpr2	NP_001038644.1
Xenopus tropicalis (tropical clawed frog)	tecpr2	XP_002936632.2
Homo sapiens (human)	TECPR2	NP_055659.2
	LOC708959	XP_002805262.1
Canis lupus familiaris (dog)	TECPR2	XP_547986.3
Mus musculus (house mouse)	Tecpr2	NP_001074526.1
Gallus gallus (chicken)	TECPR2	XP_421376.4
Pan troglodytes (chimpanzee)	TECPR2	XP_001163505.2
Rattus norvegicus (Norway rat)	Tecpr2	XP_006240679.1

Gene Ontology
Bibliography

Related articles in PubMed

WES in a family trio suggests involvement of TECPR2 in a complex form of progressive motor neuron disease.
Covone AE, Fiorillo C, Acquaviva M, Trucco F, Morana G, Ravazzolo R, Minetti C
Clinical genetics90(2)182-5(2016 Aug)

TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability.
Heimer G, Oz-Levi D, Eyal E, Edvardson S, Nissenkorn A, Ruzzo EK, Szeinberg A, Maayan C, Mai-Zahav M, Efrati O, Pras E, Reznik-Wolf H, Lancet D, Goldstein DB, Anikster Y, Shalev SA, Elpeleg O, Ben Zeev B
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society20(1)69-79(2016 Jan)

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.
Stadel D, Millarte V, Tillmann KD, Huber J, Tamin-Yecheskel BC, Akutsu M, Demishtein A, Ben-Zeev B, Anikster Y, Perez F, D?tsch V, Elazar Z, Rogov V, Farhan H, Behrends C
Molecular cell60(1)89-104(2015 Oct)

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.
Kuiper JJ, Van Setten J, Ripke S, Van 'T Slot R, Mulder F, Missotten T, Baarsma GS, Francioli LC, Pulit SL, De Kovel CG, Ten Dam-Van Loon N, Den Hollander AI, Huis in het Veld P, Hoyng CB, Cordero-Coma M, Mart?n J, Lloren? V, Arya B, Thomas D, Bakker SC, Ophoff RA, Rothova A, De Bakker PI, Mutis T, Koeleman BP
Human molecular genetics23(22)6081-7(2014 Nov)

TECPR2: a new autophagy link for neurodegeneration.
Oz-Levi D, Gelman A, Elazar Z, Lancet D
Autophagy9(5)801-2(2013 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Whole exome sequencing in an Italian pedigree suggests involvement of TECPR2 in a complex form of progressive motor neuron disease.
Title: WES in a family trio suggests involvement of TECPR2 in a complex form of progressive motor neuron disease.

The discovery of additional TECPR2 utations in non-Bukharian patients implies that this disease might be more common than previously appreciated
Title: TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability.

Results show that TECPR2 associates with several trafficking components as SEC24D and cooperates with LC3C to regulate ER exit sites and ER export suggesting that TECPR2 functions as molecular scaffold linking early secretion pathway and autophagy.
Title: TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.

The discovered TECPR2 mutation implicates autophagy, a central intracellular mechanism, in spastic paraparesis.
Title: Mutation in TECPR2 reveals a role for autophagy in hereditary spastic paraparesis.

The following TECPR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TECPR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu07890	NM_001172631.3 Latest version!	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
OHu08286	NM_014844.5 Latest version!	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$384.30 $549.00
View Old Accession Versions >>
OHu07890	NM_001172631.2	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
OHu08286	NM_014844.4	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$384.30 $549.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TECPR2 ( NM_001172631.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166102.1 Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07890
Clone ID Related Accession (Same CDS sequence)	NM_001172631.3 , NM_001172631.2
Accession Version	NM_001172631.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3804bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	tectonin beta-propeller repeat-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP365224.1, AB002327.1, AL137229.4 and BC142667.1. On Jun 1, 2019 this sequence version replaced NM_001172631.2. Transcript Variant: This variant (2) represents use of an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC142715.1, SRR1660805.76953.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGG TAAGCAGAAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166102.1
CDS	249..4052
Translation	MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGLRLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATVAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGAGLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLWLCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQVSRS

Target ORF information:

RefSeq Version	NM_001172631.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172631.3

ORF Insert Sequence:

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGG TAAGCAGAAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TECPR2 ( NM_001172631.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001166102.1 Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu07890
Clone ID Related Accession (Same CDS sequence)	NM_001172631.3 , NM_001172631.2
Accession Version	NM_001172631.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3804bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	tectonin beta-propeller repeat-containing protein 2 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP365224.1, AB002327.1, AL137229.4 and BC142667.1. On Aug 27, 2015 this sequence version replaced NM_001172631.1. Transcript Variant: This variant (2) represents use of an alternate 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC142667.1, SRR1660805.76953.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGG TAAGCAGAAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001166102.1
CDS	278..4081
Translation	MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGLRLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATVAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGAGLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLWLCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQVSRS

Target ORF information:

RefSeq Version	NM_001172631.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001172631.2

ORF Insert Sequence:

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGG TAAGCAGAAG TTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TECPR2 ( NM_014844.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055659.2 Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.

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CloneID	OHu08286
Clone ID Related Accession (Same CDS sequence)	NM_014844.4 , NM_014844.5
Accession Version	NM_014844.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4236bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	tectonin beta-propeller repeat-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP365224.1, AB002327.1, AL137229.4, BC136647.1, AL136293.5 and BQ023338.1. This sequence is a reference standard in the RefSeqGene project. On Aug 27, 2015 this sequence version replaced NM_014844.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB002327.1, BC030791.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGC CCGCCGGGGT CAGCTTGGTC AGCGTCCATT CCAGCCCCAA CGACCAGATG 
CTGTGGGTGC TTGACAGCAG GTGGAACGTG CACGTGCGGA CCGGGATCAC CGAGGAGATG 
CCTGTGGGGA CCGCCTGGGA GCATGTGCCA GGGTTGCAGG CCTGCCAGCT GGCGCTGAGC 
ACCAGGACCG TGTGGGCCCG CTGTCCAAAC GGAGACCTCG CCCGGCGGTA CGGCGTCACA 
GACAAGAACC CCGCCGGGGA CTACTGGAAG AAAATTCCCG GCAGCGTGTC GTGTTTCACA 
GTGACTGCGT CAGATGAGCT GTGGGCTGTG GGCCCGCCCG GCTACCTCCT CCAACGGCTG 
ACAAAGACGT TCAGCCACTC GCACGGCACC CAGAAGAGCA GCCAGGCCGC CATGCCCCAC 
CCTGAGGACC TGGAGGACGA GTGGGAGGTC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055659.2
CDS	278..4513
Translation	MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGLRLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATVAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGAGLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLWLCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALSTRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRLTKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI

Target ORF information:

RefSeq Version	NM_014844.4
Organism	Homo sapiens(human)
Definition	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014844.4

ORF Insert Sequence:

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGC CCGCCGGGGT CAGCTTGGTC AGCGTCCATT CCAGCCCCAA CGACCAGATG 
CTGTGGGTGC TTGACAGCAG GTGGAACGTG CACGTGCGGA CCGGGATCAC CGAGGAGATG 
CCTGTGGGGA CCGCCTGGGA GCATGTGCCA GGGTTGCAGG CCTGCCAGCT GGCGCTGAGC 
ACCAGGACCG TGTGGGCCCG CTGTCCAAAC GGAGACCTCG CCCGGCGGTA CGGCGTCACA 
GACAAGAACC CCGCCGGGGA CTACTGGAAG AAAATTCCCG GCAGCGTGTC GTGTTTCACA 
GTGACTGCGT CAGATGAGCT GTGGGCTGTG GGCCCGCCCG GCTACCTCCT CCAACGGCTG 
ACAAAGACGT TCAGCCACTC GCACGGCACC CAGAAGAGCA GCCAGGCCGC CATGCCCCAC 
CCTGAGGACC TGGAGGACGA GTGGGAGGTC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TECPR2 ( NM_014844.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_055659.2 Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.

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CloneID	OHu08286
Clone ID Related Accession (Same CDS sequence)	NM_014844.4 , NM_014844.5
Accession Version	NM_014844.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4236bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-22
Organism	Homo sapiens(human)
Product	tectonin beta-propeller repeat-containing protein 2 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP365224.1, AB002327.1, AL137229.4, BC136647.1, AL136293.5 and BQ023338.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_014844.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AB002327.1, BC030791.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000359520.12/ ENSP00000352510.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGC CCGCCGGGGT CAGCTTGGTC AGCGTCCATT CCAGCCCCAA CGACCAGATG 
CTGTGGGTGC TTGACAGCAG GTGGAACGTG CACGTGCGGA CCGGGATCAC CGAGGAGATG 
CCTGTGGGGA CCGCCTGGGA GCATGTGCCA GGGTTGCAGG CCTGCCAGCT GGCGCTGAGC 
ACCAGGACCG TGTGGGCCCG CTGTCCAAAC GGAGACCTCG CCCGGCGGTA CGGCGTCACA 
GACAAGAACC CCGCCGGGGA CTACTGGAAG AAAATTCCCG GCAGCGTGTC GTGTTTCACA 
GTGACTGCGT CAGATGAGCT GTGGGCTGTG GGCCCGCCCG GCTACCTCCT CCAACGGCTG 
ACAAAGACGT TCAGCCACTC GCACGGCACC CAGAAGAGCA GCCAGGCCGC CATGCCCCAC 
CCTGAGGACC TGGAGGACGA GTGGGAGGTC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055659.2
CDS	249..4484
Translation	MASISEPVTFREFCPLYYLLNAIPTKIQKGFRSIVVYLTALDTNGDYIAVGSSIGMLYLYCRHLNQMRKYNFEGKTESITVVKLLSCFDDLVAAGTASGRVAVFQLVSSLPGRNKQLRRFDVTGIHKNSITALAWSPNGMKLFSGDDKGKIVYSSLDLDQGLCNSQLVLEEPSSIVQLDYSQKVLLVSTLQRSLLFYTEEKSVRQIGTQPRKSTGKFGACFIPGLCKQSDLTLYASRPGLRLWKADVHGTVQATFILKDAFAGGVKPFELHPRLESPNSGSCSLPERHLGLVSCFFQEGWVLSWNEYSIYLLDTVNQATVAGLEGSGDIVSVSCTENEIFFLKGDRNIIRISSRPEGLTSTVRDGLEMSGCSERVHVQQAEKLPGATVSETRLRGSSMASSVASEPRSRSSSLNSTDSGSGLLPPGLQATPELGKGSQPLSQRFNAISSEDFDQELVVKPIKVKRKKKKKKTEGGSRSTCHSSLESTPCSEFPGDSPQSLNTDLLSMTSSVLGSSVDQLSAESPDQESSFNGEVNGVPQENTDPETFNVLEVSGSMPDSLAEEDDIRTEMPHCHHAHGRELLNGAREDVGGSDVTGLGDEPCPADDGPNSTQLPFQEQDSSPGAHDGEDIQPIGPQSTFCEVPLLNSLTVPSSLSWAPSAEQWLPGTRADEGSPVEPSQEQDILTSMEASGHLSTNLWHAVTDDDTGQKEIPISERVLGSVGGQLTPVSALAASTHKPWLEQPPRDQTLTSSDEEDIYAHGLPSSSSETSVTELGPSCSQQDLSRLGAEDAGLLKPDQFAESWMGYSGPGYGILSLVVSEKYIWCLDYKGGLFCSALPGAGLRWQKFEDAVQQVAVSPSGALLWKIEQKSNRAFACGKVTIKGKRHWYEALPQAVFVALSDDTAWIIRTSGDLYLQTGLSVDRPCARAVKVDCPYPLSQITARNNVVWALTEQRALLYREGVSSFCPEGEQWKCDIVSERQALEPVCITLGDQQTLWALDIHGNLWFRTGIISKKPQGDDDHWWQVSITDYVVFDQCSLFQTIIHATHSVATAAQAPVEKVADKLRMAFWSQQLQCQPSLLGVNNSGVWISSGKNEFHVAKGSLIGTYWNHVVPRGTASATKWAFVLASAAPTKEGSFLWLCQSSKDLCSVSAQSAQSRPSTVQLPPEAEMRAYAACQDALWALDSLGQVFIRTLSKSCPTGMHWTRLDLSQLGAVKLTSLACGNQHIWACDSRGGVYFRVGTQPLNPSLMLPAWIMIEPPVQPAGVSLVSVHSSPNDQMLWVLDSRWNVHVRTGITEEMPVGTAWEHVPGLQACQLALSTRTVWARCPNGDLARRYGVTDKNPAGDYWKKIPGSVSCFTVTASDELWAVGPPGYLLQRLTKTFSHSHGTQKSSQAAMPHPEDLEDEWEVI

Target ORF information:

RefSeq Version	NM_014844.5
Organism	Homo sapiens(human)
Definition	Homo sapiens tectonin beta-propeller repeat containing 2 (TECPR2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014844.5

ORF Insert Sequence:

ATGGCATCGA TATCAGAGCC TGTTACATTC AGAGAGTTCT GCCCGTTGTA CTATCTCCTC 
AATGCCATTC CGACAAAGAT CCAGAAGGGT TTCCGCTCTA TCGTGGTCTA TCTCACGGCC 
CTCGACACCA ACGGGGACTA CATCGCGGTG GGCAGCAGCA TCGGCATGCT CTATCTGTAC 
TGCCGGCACC TCAACCAGAT GAGGAAGTAC AACTTTGAGG GGAAGACGGA ATCTATCACT 
GTGGTGAAGC TGCTGAGCTG CTTTGATGAC CTGGTGGCAG CAGGCACAGC CTCTGGCAGG 
GTTGCAGTTT TTCAACTTGT ATCTTCATTG CCAGGGAGAA ATAAACAGCT TCGGAGATTT 
GATGTCACTG GTATTCACAA AAATAGCATT ACAGCTCTGG CTTGGAGCCC CAATGGAATG 
AAATTGTTCT CTGGAGATGA CAAAGGCAAA ATTGTTTATT CTTCTCTGGA TCTAGACCAG 
GGGCTCTGTA ACTCCCAGCT GGTGTTGGAG GAGCCATCTT CCATTGTGCA GCTGGATTAT 
AGCCAGAAAG TGCTGCTGGT CTCTACTCTG CAAAGAAGTC TGCTCTTTTA CACTGAAGAA 
AAGTCTGTAA GGCAAATTGG AACACAACCA AGGAAAAGTA CTGGGAAATT TGGTGCTTGT 
TTTATACCAG GACTCTGTAA GCAAAGTGAT CTAACCTTGT ATGCGTCACG GCCCGGGCTC 
CGGCTATGGA AGGCTGATGT CCACGGGACT GTTCAAGCCA CGTTTATCTT AAAAGATGCT 
TTTGCCGGGG GAGTCAAGCC TTTTGAACTG CACCCGCGTC TGGAATCCCC CAACAGTGGA 
AGTTGCAGCT TACCTGAGAG GCACCTGGGG CTTGTTTCAT GTTTCTTTCA AGAAGGCTGG 
GTGCTGAGTT GGAATGAATA TAGTATCTAT CTCCTAGACA CAGTCAACCA GGCCACAGTT 
GCTGGTTTGG AAGGATCCGG TGATATTGTG TCTGTTTCGT GCACAGAAAA TGAAATATTT 
TTCTTGAAAG GAGATAGGAA CATTATAAGA ATTTCAAGCA GGCCTGAAGG ATTAACATCA 
ACAGTGAGAG ATGGTCTGGA GATGTCTGGA TGCTCAGAGC GTGTCCACGT GCAGCAAGCG 
GAGAAGCTGC CAGGGGCCAC AGTTTCTGAG ACGAGGCTCA GAGGCTCTTC CATGGCCAGC 
TCCGTGGCCA GCGAGCCAAG GAGCAGGAGC AGCTCGCTCA ACTCCACCGA CAGCGGCTCC 
GGGCTCCTGC CCCCTGGGCT CCAGGCCACC CCTGAGCTGG GCAAGGGCAG CCAGCCCCTG 
TCACAGAGAT TCAACGCCAT CAGCTCAGAG GACTTTGACC AGGAGCTTGT CGTGAAGCCT 
ATCAAAGTGA AAAGGAAGAA GAAGAAGAAG AAGACAGAAG GTGGAAGCAG GAGCACCTGT 
CACAGCTCCC TGGAATCGAC ACCCTGCTCC GAATTTCCTG GGGACAGTCC CCAGTCCTTG 
AACACAGACT TGCTGTCGAT GACCTCAAGT GTCCTGGGCA GTAGCGTGGA TCAGTTAAGT 
GCAGAGTCTC CAGACCAGGA AAGCAGCTTC AATGGTGAAG TGAACGGTGT CCCACAGGAA 
AATACTGACC CCGAAACGTT TAATGTCCTG GAGGTGTCAG GATCAATGCC TGATTCTCTG 
GCTGAGGAAG ATGACATTAG AACTGAAATG CCACACTGTC ACCATGCACA TGGGCGGGAG 
CTGCTCAATG GAGCGAGGGA AGATGTGGGA GGCAGTGATG TCACGGGACT CGGAGATGAG 
CCGTGTCCTG CAGATGATGG ACCAAATAGC ACACAGTTAC CCTTCCAAGA ACAGGACAGC 
TCTCCTGGGG CGCATGATGG GGAAGACATC CAACCCATTG GCCCCCAAAG CACTTTTTGT 
GAAGTCCCCC TCCTGAACTC ACTCACTGTG CCTTCCAGCC TCAGCTGGGC CCCAAGTGCT 
GAACAGTGGC TGCCTGGGAC CAGAGCTGAT GAAGGCAGCC CCGTGGAGCC CAGCCAAGAG 
CAGGACATCC TAACCAGCAT GGAGGCCTCT GGCCACCTCA GCACAAATCT CTGGCATGCT 
GTCACTGATG ATGACACAGG TCAGAAAGAA ATACCCATTT CTGAACGTGT CTTGGGGAGT 
GTGGGAGGAC AGCTGACTCC GGTCTCTGCC TTGGCAGCCA GCACTCACAA GCCCTGGCTT 
GAGCAGCCTC CACGGGATCA GACATTGACG TCCAGCGATG AGGAGGACAT CTATGCCCAC 
GGGCTTCCTT CTTCATCCTC AGAGACGAGT GTGACAGAGC TCGGACCTAG TTGCTCCCAG 
CAGGACCTGA GCCGGCTGGG TGCAGAGGAC GCCGGGCTGC TCAAGCCAGA TCAGTTTGCA 
GAAAGCTGGA TGGGCTACTC GGGTCCCGGC TATGGCATCC TCAGCTTGGT GGTCTCCGAG 
AAGTATATCT GGTGCCTGGA CTACAAAGGC GGCCTGTTCT GCAGCGCGTT GCCGGGCGCC 
GGGCTGCGCT GGCAGAAGTT TGAAGATGCT GTCCAGCAGG TGGCAGTCTC GCCCTCAGGA 
GCCCTTCTCT GGAAGATTGA ACAGAAATCT AACCGGGCTT TTGCTTGTGG GAAAGTCACC 
ATCAAGGGGA AGCGGCACTG GTACGAAGCC CTGCCCCAGG CAGTGTTTGT GGCCCTGAGC 
GATGACACGG CCTGGATCAT CAGGACCAGT GGGGACCTAT ACTTGCAGAC AGGTCTGAGC 
GTGGATCGCC CTTGTGCCAG AGCCGTAAAG GTGGACTGTC CCTACCCGCT GTCCCAGATC 
ACAGCCCGGA ACAATGTGGT GTGGGCGCTG ACAGAGCAGA GGGCCCTCCT GTACCGGGAG 
GGCGTGAGCA GCTTCTGTCC GGAAGGCGAG CAGTGGAAGT GTGACATTGT CAGCGAAAGG 
CAAGCTTTAG AACCCGTCTG CATAACGCTC GGGGATCAGC AGACTCTCTG GGCCCTGGAC 
ATCCATGGGA ACCTGTGGTT CAGAACTGGC ATTATTTCCA AGAAGCCCCA AGGAGATGAC 
GACCATTGGT GGCAAGTGAG CATCACGGAC TATGTGGTGT TTGACCAGTG CAGCTTATTT 
CAGACGATAA TCCATGCCAC TCACTCGGTG GCCACAGCAG CCCAAGCCCC CGTAGAAAAG 
GTGGCAGATA AGCTGCGCAT GGCGTTTTGG TCCCAGCAGC TTCAGTGCCA GCCAAGCCTT 
CTCGGGGTCA ATAACAGCGG TGTCTGGATC TCCTCGGGCA AGAATGAATT CCACGTCGCT 
AAGGGAAGTC TCATAGGCAC CTACTGGAAT CATGTGGTTC CCCGTGGGAC AGCTTCTGCT 
ACAAAATGGG CCTTTGTGTT GGCTTCTGCA GCTCCCACGA AGGAAGGAAG CTTCCTGTGG 
CTGTGCCAGA GCAGCAAGGA CCTGTGCAGC GTCAGCGCCC AGAGCGCACA GTCGCGGCCC 
TCCACGGTGC AGCTGCCTCC CGAAGCCGAG ATGCGCGCCT ATGCCGCCTG CCAGGATGCG 
CTGTGGGCGC TGGACAGCCT CGGCCAGGTG TTCATCAGGA CGCTCTCCAA GAGCTGCCCC 
ACGGGCATGC ACTGGACCAG GCTGGACCTC TCCCAGCTAG GAGCTGTAAA ATTGACAAGC 
TTGGCATGTG GAAATCAGCA CATCTGGGCC TGTGATTCCA GGGGTGGAGT TTACTTCCGT 
GTAGGGACTC AGCCTCTCAA TCCCAGTCTC ATGCTTCCAG CCTGGATAAT GATTGAGCCA 
CCTGTCCAGC CCGCCGGGGT CAGCTTGGTC AGCGTCCATT CCAGCCCCAA CGACCAGATG 
CTGTGGGTGC TTGACAGCAG GTGGAACGTG CACGTGCGGA CCGGGATCAC CGAGGAGATG 
CCTGTGGGGA CCGCCTGGGA GCATGTGCCA GGGTTGCAGG CCTGCCAGCT GGCGCTGAGC 
ACCAGGACCG TGTGGGCCCG CTGTCCAAAC GGAGACCTCG CCCGGCGGTA CGGCGTCACA 
GACAAGAACC CCGCCGGGGA CTACTGGAAG AAAATTCCCG GCAGCGTGTC GTGTTTCACA 
GTGACTGCGT CAGATGAGCT GTGGGCTGTG GGCCCGCCCG GCTACCTCCT CCAACGGCTG 
ACAAAGACGT TCAGCCACTC GCACGGCACC CAGAAGAGCA GCCAGGCCGC CATGCCCCAC 
CCTGAGGACC TGGAGGACGA GTGGGAGGTC ATCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

WES in a family trio suggests involvement of TECPR2 in a complex form of progressive motor neuron disease.
Clinical genetics90(2)182-5(2016 Aug)
Covone AE,Fiorillo C,Acquaviva M,Trucco F,Morana G,Ravazzolo R,Minetti C

TECPR2 mutations cause a new subtype of familial dysautonomia like hereditary sensory autonomic neuropathy with intellectual disability.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society20(1)69-79(2016 Jan)
Heimer G,Oz-Levi D,Eyal E,Edvardson S,Nissenkorn A,Ruzzo EK,Szeinberg A,Maayan C,Mai-Zahav M,Efrati O,Pras E,Reznik-Wolf H,Lancet D,Goldstein DB,Anikster Y,Shalev SA,Elpeleg O,Ben Zeev B

TECPR2 Cooperates with LC3C to Regulate COPII-Dependent ER Export.
Molecular cell60(1)89-104(2015 Oct)
Stadel D,Millarte V,Tillmann KD,Huber J,Tamin-Yecheskel BC,Akutsu M,Demishtein A,Ben-Zeev B,Anikster Y,Perez F,D?tsch V,Elazar Z,Rogov V,Farhan H,Behrends C

A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy.
Human molecular genetics23(22)6081-7(2014 Nov)
Kuiper JJ,Van Setten J,Ripke S,Van 'T Slot R,Mulder F,Missotten T,Baarsma GS,Francioli LC,Pulit SL,De Kovel CG,Ten Dam-Van Loon N,Den Hollander AI,Huis in het Veld P,Hoyng CB,Cordero-Coma M,Mart?n J,Lloren? V,Arya B,Thomas D,Bakker SC,Ophoff RA,Rothova A,De Bakker PI,Mutis T,Koeleman BP

TECPR2: a new autophagy link for neurodegeneration.
Autophagy9(5)801-2(2013 May)
Oz-Levi D,Gelman A,Elazar Z,Lancet D

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TECPR2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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