ARHGEF17 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ARHGEF17
Entrez Gene ID	9828
Full Name	Rho guanine nucleotide exchange factor 17
Synonyms	P164RHOGEF,RHOGEF17,TEM4,p164-RhoGEF
General protein information	Preferred Names Rho guanine nucleotide exchange factor 17 Names rho guanine nucleotide exchange factor 17 164 kDa Rho-specific guanine-nucleotide exchange factor Rho guanine nucleotide exchange factor (GEF) 17 Rho-specific guanine-nucleotide exchange factor 164 kDa tumor endothelial marker 4
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q13.4
Disorder MIM:	617043

mRNA and Protein(s)

mRNA	Protein	Name
XM_017018623.1	XP_016874112.1	rho guanine nucleotide exchange factor 17 isoform X1
XM_017018624.1	XP_016874113.1	rho guanine nucleotide exchange factor 17 isoform X2
NM_014786.4	NP_055601.2	rho guanine nucleotide exchange factor 17
NM_014786.3	NP_055601.2	rho guanine nucleotide exchange factor 17

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ARHGEF17	XP_003952045.1
Danio rerio (zebrafish)	si:ch211-248g20.5	XP_003200462.1
Homo sapiens (human)	ARHGEF17	NP_055601.2
	ARHGEF17	XP_001115376.1
Rattus norvegicus (Norway rat)	Arhgef17	XP_003748980.1
Gallus gallus (chicken)	ARHGEF17	XP_003640675.2
Xenopus tropicalis (tropical clawed frog)	arhgef17	XP_002943175.2
Canis lupus familiaris (dog)	ARHGEF17	XP_005633593.1
Mus musculus (house mouse)	Arhgef17	NP_001074585.1
Bos taurus (cattle)	ARHGEF17	XP_005201010.1

Gene Ontology
Bibliography

Related articles in PubMed

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
Isokane M, Walter T, Mahen R, Nijmeijer B, H?rich? JK, Miura K, Maffini S, Ivanov MP, Kitajima TS, Peters JM, Ellenberg J
The Journal of cell biology212(6)647-59(2016 Mar)

RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase I?.
Lutz S, Mohl M, Rauch J, Weber P, Wieland T
Cellular signalling25(3)630-8(2013 Mar)

The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility.
Mitin N, Rossman KL, Currin R, Anne S, Marshall TW, Bear JE, Bautch VL, Der CJ
PloS one8(6)e66260(2013)

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
Hancock DB, Soler Artigas M, Gharib SA, Henry A, Manichaikul A, Ramasamy A, Loth DW, Imboden M, Koch B, McArdle WL, Smith AV, Smolonska J, Sood A, Tang W, Wilk JB, Zhai G, Zhao JH, Aschard H, Burkart KM, Curjuric I, Eijgelsheim M, Elliott P, Gu X, Harris TB, Janson C, Homuth G, Hysi PG, Liu JZ, Loehr LR, Lohman K, Loos RJ, Manning AK, Marciante KD, Obeidat M, Postma DS, Aldrich MC, Brusselle GG, Chen TH, Eiriksdottir G, Franceschini N, Heinrich J, Rotter JI, Wijmenga C, Williams OD, Bentley AR, Hofman A, Laurie CC, Lumley T, Morrison AC, Joubert BR, Rivadeneira F, Couper DJ, Kritchevsky SB, Liu Y, Wjst M, Wain LV, Vonk JM, Uitterlinden AG, Rochat T, Rich SS, Psaty BM, O'Connor GT, North KE, Mirel DB, Meibohm B, Launer LJ, Khaw KT, Hartikainen AL, Hammond CJ, Gl?ser S, Marchini J, Kraft P, Wareham NJ, V?lzke H, Stricker BH, Spector TD, Probst-Hensch NM, Jarvis D, Jarvelin MR, Heckbert SR, Gudnason V, Boezen HM, Barr RG, Cassano PA, Strachan DP, Fornage M, Hall IP, Dupuis J, Tobin MD, London SJ
PLoS genetics8(12)e1003098(2012)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Interaction of the central domain of ARHGEF17 with Mps1.
Title: ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.

The rho guanine nucleotide exchange factor 17 is drastically alter the effect of cGMP/cGK involving signaling pathways on RhoA-activated downstream effectors.
Title: RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase I?.

data implicate TEM4 as an essential regulator of the actin cytoskeleton that ensures proper membrane protrusion at the leading edge of migrating cells and efficient cellular migration via suppression of actomyosin contractility
Title: The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility.

TEM4 contains a novel actin binding domain and binding to actin is essential for TEM4 subcellular localization and activity.
Title: Identification of a novel actin-binding domain within the Rho guanine nucleotide exchange factor TEM4.

Observational study of gene-disease association. (HuGE Navigator)
Title: Mutation of ARHGAP9 in patients with coronary spastic angina.

The following ARHGEF17 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARHGEF17 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu83416	XM_017018624.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	10-12	$475.30 $679.00
OHu83415	XM_017018623.1 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	19-21	$559.30 $799.00
OHu31458	NM_014786.4 Latest version!	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1091.30 $1559.00
View Old Accession Versions >>
OHu31458	NM_014786.3	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$1091.30 $1559.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ARHGEF17 ( XM_017018624.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874113.1 Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X5, mRNA.

Price & Availability↑

CloneID	OHu83416
Clone ID Related Accession (Same CDS sequence)	XM_017018624.1
Accession Version	XM_017018624.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2916bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 17 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGCCGC TGAAGCAGCC AGAGAACTCC GTGCTCTGTG ACCCTTCACT GGTGGACGAG 
ATCTTCGACC AGATCCCCGA GCTCCTGGAG CACCACGAGC AATTCCTGGA GCAGGTTCGG 
CACTGCATGC AGACCTGGCA TGCCCAGCAG AAGGTGGGAG CCCTGCTCGT CCAGTCGTTC 
TCCAAGGATG TCCTAGTAAA CATCTATTCT GCCTATATCG ATAACTTCCT CAATGCAAAG 
GATGCTGTGC GTGTGGCCAA GGAGGCGAGG CCTGCCTTTC TCAAGTTCCT AGAGCAAAGC 
ATGCGTGAGA ACAAGGAGAA GCAGGCGCTG TCTGACCTCA TGATCAAGCC TGTGCAGCGG 
ATCCCACGCT ACGAGCTTCT GGTGAAGGAC CTCCTGAAGC ATACACCTGA GGACCACCCG 
GACCATCCAC TCCTGCTGGA GGCGCAGCGG AACATCAAGC AGGTGGCTGA GCGCATCAAC 
AAGGGTGTGC GGAGTGCCGA GGAGGCGGAG CGCCATGCCC GTGTGCTGCA GGAGATAGAG 
GCTCACATCG AGGGCATGGA GGATCTCCAG GCCCCTCTGC GGCGGTTCCT GAGACAGGAG 
ATGGTCATTG AAGTGAAGGC GATCGGTGGC AAGAAGGACC GGTCTCTCTT CCTGTTCACG 
GACCTCATCG TCTGCACCAC TCTGAAGCGA AAGTCAGGCT CCCTGCGGCG CAGCTCCATG 
AGCCTGTACA CGGCAGCCAG TGTCATTGAC ACAGCCAGCA AGTACAAGAT GCTGTGGAAG 
CTGCCGCTGG AAGACGCAGA CATCATCAAA GGGGCATCCC AAGCCACCAA TCGGGAGAAC 
ATCCAGAAGG CCATCAGCCG CCTTGATGAG GACCTCACCA CCCTGGGCCA AATGAGCAAG 
CTCTCTGAGA GCCTTGGTTT CCCCCACCAG AGCCTGGACG ATGCACTGCG GGACCTCTCA 
GCTGCCATGC ACCGGGACCT GTCGGAGAAG CAGGCGCTGT GCTACGCGCT TTCCTTCCCG 
CCAACCAAGC TGGAGCTGTG CGCCACTCGG CCCGAGGGCA CCGACTCCTA CATTTTTGAG 
TTCCCTCACC CTGACGCCCG CCTTGGTTTT GAACAGGCCT TCGATGAGGC CAAGAGGAAG 
CTGGCATCCA GCAAAAGCTG TCTAGACCCT GAGTTCCTGA AGGCCATCCC CATCATGAAA 
ACCCGCAGTG GCATGCAGTT CTCCTGTGCG GCTCCCACCC TGAACAGCTG CCCGGAGCCC 
TCGCCTGAGG TATGGGTCTG CAACAGCGAC GGCTACGTGG GCCAGGTGTG CCTGCTGAGC 
CTGCGCGCCG AGCCGGACGT GGAGGCCTGC ATCGCCGTCT GTTCCGCCCG CATCCTCTGC 
ATCGGGGCGG TGCCCGGGCT GCAGCCTCGC TGCCACCGGG AGCCTCCTCC GTCGCTGAGG 
AGTCCTCCAG AGACGGCACC GGAGCCCGCC GGGCCGGAGC TGGACGTCGA GGCCGCTGCA 
GACGAGGAAG CCGCGACGCT CGCGGAGCCG GGGCCGCAGC CCTGCCTTCA CATCTCCATT 
GCAGGCTCGG GCTTGGAGAT GACGCCGGGC CTCGGCGAGG GTGACCCCCG CCCAGAGCTG 
GTGCCCTTTG ACAGTGACTC TGACGATGAG TCTTCGCCCA GCCCCTCGGG GACGCTGCAG 
AGCCAGGCCA GCCGGTCCAC CATCTCCTCC AGCTTTGGCA ATGAGGAGAC CCCGAGTTCC 
AAGGAGGCCA CGGCAGAGAC CACCAGCTCA GAGGAGGAGC AGGAGCCAGG CTTCCTGCCA 
CTGTCTGGCT CCTTTGGGCC TGGTGGTCCC TGCGGCACCA GCCCAATGGA TGGGAGAGCC 
CTTCGCCGCT CCAGCCACGG CTCCTTCACC CGGGGCAGCC TTGAGGACCT GCTGAGTGTC 
GACCCTGAGG CCTACCAGAG CTCCGTGTGG CTGGGCACTG AGGATGGCTG TGTCCACGTG 
TACCAGTCCT CCGACAGCAT CCGTGACCGC AGGAACAGCA TGAAGCTCCA GCATGCGGCC 
TCTGTGACCT GCATCTTGTA TCTGAATAAC CAGGTGTTTG TGTCTCTGGC CAATGGAGAG 
CTTGTGGTCT ACCAAAGGGA AGCAGGCCAT TTCTGGGACC CCCAGAACTT CAAATCAGTG 
ACCTTGGGCA CCCAGGGGAG CCCCATCACC AAGATGGTAT CTGTGGGTGG GCGGCTGTGG 
TGTGGCTGCC AGAACCGAGT CCTTGTCCTG AGCCCTGACA CGCTGCAGCT GGAGCACATG 
TTTTACGTGG GTCAGGATTC AAGCCGCTGC GTGGCTTGCA TGGTGGACTC CAGCCTGGGT 
GTGTGGGTGA CATTGAAAGG TAGTGCCCAC GTGTGTCTCT ACCATCCAGA CACCTTTGAG 
CAGCTGGCAG AAGTAGACGT CACTCCTCCC GTGCACAGGA TGCTGGCAGG CTCGGATGCC 
ATCATCCGGC AGCACAAGGC TGCCTGTCTG CGAATCACAG CGCTGCTGGT GTGTGAGGAG 
CTGCTGTGGG TGGGCACCAG TGCTGGTGTC GTCCTCACCA TGCCCACTTC GCCCGGTACT 
GTCAGCTGCC CACGGGCACC ACTCAGTCCC ACAGGCCTCG GCCAGGGACA CACCGGCCAC 
GTCCGCTTCT TGGCTGCAGT CCAGCTGCCA GATGGCTTCA ACCTGCTCTG CCCAACCCCA 
CCACCTCCCC CAGACACAGG CCCCGAGAAG CTGCCATCAC TGGAGCACCG GGACTCCCCT 
TGGCACCGAG GCCCCGCCCC TGCCAGGCCT AAAATGCTGG TTATCAGTGG AGGTGATGGC 
TATGAGGACT TCCGACTCAG CAGTGGGGGC GGCAGCAGCA GTGAGACTGT GGGTCGAGAC 
GACAGCACAA ACCACCTCCT CCTGTGGAGG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874113.1
CDS	768..3683
Translation	MQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Target ORF information:

RefSeq Version	XM_017018624.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018624.1

ORF Insert Sequence:

ATGCAGCCGC TGAAGCAGCC AGAGAACTCC GTGCTCTGTG ACCCTTCACT GGTGGACGAG 
ATCTTCGACC AGATCCCCGA GCTCCTGGAG CACCACGAGC AATTCCTGGA GCAGGTTCGG 
CACTGCATGC AGACCTGGCA TGCCCAGCAG AAGGTGGGAG CCCTGCTCGT CCAGTCGTTC 
TCCAAGGATG TCCTAGTAAA CATCTATTCT GCCTATATCG ATAACTTCCT CAATGCAAAG 
GATGCTGTGC GTGTGGCCAA GGAGGCGAGG CCTGCCTTTC TCAAGTTCCT AGAGCAAAGC 
ATGCGTGAGA ACAAGGAGAA GCAGGCGCTG TCTGACCTCA TGATCAAGCC TGTGCAGCGG 
ATCCCACGCT ACGAGCTTCT GGTGAAGGAC CTCCTGAAGC ATACACCTGA GGACCACCCG 
GACCATCCAC TCCTGCTGGA GGCGCAGCGG AACATCAAGC AGGTGGCTGA GCGCATCAAC 
AAGGGTGTGC GGAGTGCCGA GGAGGCGGAG CGCCATGCCC GTGTGCTGCA GGAGATAGAG 
GCTCACATCG AGGGCATGGA GGATCTCCAG GCCCCTCTGC GGCGGTTCCT GAGACAGGAG 
ATGGTCATTG AAGTGAAGGC GATCGGTGGC AAGAAGGACC GGTCTCTCTT CCTGTTCACG 
GACCTCATCG TCTGCACCAC TCTGAAGCGA AAGTCAGGCT CCCTGCGGCG CAGCTCCATG 
AGCCTGTACA CGGCAGCCAG TGTCATTGAC ACAGCCAGCA AGTACAAGAT GCTGTGGAAG 
CTGCCGCTGG AAGACGCAGA CATCATCAAA GGGGCATCCC AAGCCACCAA TCGGGAGAAC 
ATCCAGAAGG CCATCAGCCG CCTTGATGAG GACCTCACCA CCCTGGGCCA AATGAGCAAG 
CTCTCTGAGA GCCTTGGTTT CCCCCACCAG AGCCTGGACG ATGCACTGCG GGACCTCTCA 
GCTGCCATGC ACCGGGACCT GTCGGAGAAG CAGGCGCTGT GCTACGCGCT TTCCTTCCCG 
CCAACCAAGC TGGAGCTGTG CGCCACTCGG CCCGAGGGCA CCGACTCCTA CATTTTTGAG 
TTCCCTCACC CTGACGCCCG CCTTGGTTTT GAACAGGCCT TCGATGAGGC CAAGAGGAAG 
CTGGCATCCA GCAAAAGCTG TCTAGACCCT GAGTTCCTGA AGGCCATCCC CATCATGAAA 
ACCCGCAGTG GCATGCAGTT CTCCTGTGCG GCTCCCACCC TGAACAGCTG CCCGGAGCCC 
TCGCCTGAGG TATGGGTCTG CAACAGCGAC GGCTACGTGG GCCAGGTGTG CCTGCTGAGC 
CTGCGCGCCG AGCCGGACGT GGAGGCCTGC ATCGCCGTCT GTTCCGCCCG CATCCTCTGC 
ATCGGGGCGG TGCCCGGGCT GCAGCCTCGC TGCCACCGGG AGCCTCCTCC GTCGCTGAGG 
AGTCCTCCAG AGACGGCACC GGAGCCCGCC GGGCCGGAGC TGGACGTCGA GGCCGCTGCA 
GACGAGGAAG CCGCGACGCT CGCGGAGCCG GGGCCGCAGC CCTGCCTTCA CATCTCCATT 
GCAGGCTCGG GCTTGGAGAT GACGCCGGGC CTCGGCGAGG GTGACCCCCG CCCAGAGCTG 
GTGCCCTTTG ACAGTGACTC TGACGATGAG TCTTCGCCCA GCCCCTCGGG GACGCTGCAG 
AGCCAGGCCA GCCGGTCCAC CATCTCCTCC AGCTTTGGCA ATGAGGAGAC CCCGAGTTCC 
AAGGAGGCCA CGGCAGAGAC CACCAGCTCA GAGGAGGAGC AGGAGCCAGG CTTCCTGCCA 
CTGTCTGGCT CCTTTGGGCC TGGTGGTCCC TGCGGCACCA GCCCAATGGA TGGGAGAGCC 
CTTCGCCGCT CCAGCCACGG CTCCTTCACC CGGGGCAGCC TTGAGGACCT GCTGAGTGTC 
GACCCTGAGG CCTACCAGAG CTCCGTGTGG CTGGGCACTG AGGATGGCTG TGTCCACGTG 
TACCAGTCCT CCGACAGCAT CCGTGACCGC AGGAACAGCA TGAAGCTCCA GCATGCGGCC 
TCTGTGACCT GCATCTTGTA TCTGAATAAC CAGGTGTTTG TGTCTCTGGC CAATGGAGAG 
CTTGTGGTCT ACCAAAGGGA AGCAGGCCAT TTCTGGGACC CCCAGAACTT CAAATCAGTG 
ACCTTGGGCA CCCAGGGGAG CCCCATCACC AAGATGGTAT CTGTGGGTGG GCGGCTGTGG 
TGTGGCTGCC AGAACCGAGT CCTTGTCCTG AGCCCTGACA CGCTGCAGCT GGAGCACATG 
TTTTACGTGG GTCAGGATTC AAGCCGCTGC GTGGCTTGCA TGGTGGACTC CAGCCTGGGT 
GTGTGGGTGA CATTGAAAGG TAGTGCCCAC GTGTGTCTCT ACCATCCAGA CACCTTTGAG 
CAGCTGGCAG AAGTAGACGT CACTCCTCCC GTGCACAGGA TGCTGGCAGG CTCGGATGCC 
ATCATCCGGC AGCACAAGGC TGCCTGTCTG CGAATCACAG CGCTGCTGGT GTGTGAGGAG 
CTGCTGTGGG TGGGCACCAG TGCTGGTGTC GTCCTCACCA TGCCCACTTC GCCCGGTACT 
GTCAGCTGCC CACGGGCACC ACTCAGTCCC ACAGGCCTCG GCCAGGGACA CACCGGCCAC 
GTCCGCTTCT TGGCTGCAGT CCAGCTGCCA GATGGCTTCA ACCTGCTCTG CCCAACCCCA 
CCACCTCCCC CAGACACAGG CCCCGAGAAG CTGCCATCAC TGGAGCACCG GGACTCCCCT 
TGGCACCGAG GCCCCGCCCC TGCCAGGCCT AAAATGCTGG TTATCAGTGG AGGTGATGGC 
TATGAGGACT TCCGACTCAG CAGTGGGGGC GGCAGCAGCA GTGAGACTGT GGGTCGAGAC 
GACAGCACAA ACCACCTCCT CCTGTGGAGG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF17 ( XM_017018623.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016874112.1 Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu83415
Clone ID Related Accession (Same CDS sequence)	XM_017018623.1
Accession Version	XM_017018623.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3174bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 17 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGTGCTG CTTTATCCGT CCAGGACTCC GTGCGTTGGG AAAATCACGC CGCGAGGGGG 
CGCAAGAGCC GCGTACTCCA GAGCAAGAAG AAAAGGCTCG GGGATCCAGG CGGAGAGTCC 
AGGAGAAGAG CCGCCAGACT GCAGGGGCAG GTGGAAGGCG TGGCAGCTGG AAAAGACATG 
CGGAAGCACG TGGCCATGAC CCTGCTGGAC ACAGAGCAGT CGTATGTGGA GTCGCTGCGC 
ACCCTGATGC AGGGCTACAT GCAGCCGCTG AAGCAGCCAG AGAACTCCGT GCTCTGTGAC 
CCTTCACTGG TGGACGAGAT CTTCGACCAG ATCCCCGAGC TCCTGGAGCA CCACGAGCAA 
TTCCTGGAGC AGGTTCGGCA CTGCATGCAG ACCTGGCATG CCCAGCAGAA GGTGGGAGCC 
CTGCTCGTCC AGTCGTTCTC CAAGGATGTC CTAGTAAACA TCTATTCTGC CTATATCGAT 
AACTTCCTCA ATGCAAAGGA TGCTGTGCGT GTGGCCAAGG AGGCGAGGCC TGCCTTTCTC 
AAGTTCCTAG AGCAAAGCAT GCGTGAGAAC AAGGAGAAGC AGGCGCTGTC TGACCTCATG 
ATCAAGCCTG TGCAGCGGAT CCCACGCTAC GAGCTTCTGG TGAAGGACCT CCTGAAGCAT 
ACACCTGAGG ACCACCCGGA CCATCCACTC CTGCTGGAGG CGCAGCGGAA CATCAAGCAG 
GTGGCTGAGC GCATCAACAA GGGTGTGCGG AGTGCCGAGG AGGCGGAGCG CCATGCCCGT 
GTGCTGCAGG AGATAGAGGC TCACATCGAG GGCATGGAGG ATCTCCAGGC CCCTCTGCGG 
CGGTTCCTGA GACAGGAGAT GGTCATTGAA GTGAAGGCGA TCGGTGGCAA GAAGGACCGG 
TCTCTCTTCC TGTTCACGGA CCTCATCGTC TGCACCACTC TGAAGCGAAA GTCAGGCTCC 
CTGCGGCGCA GCTCCATGAG CCTGTACACG GCAGCCAGTG TCATTGACAC AGCCAGCAAG 
TACAAGATGC TGTGGAAGCT GCCGCTGGAA GACGCAGACA TCATCAAAGG GGCATCCCAA 
GCCACCAATC GGGAGAACAT CCAGAAGGCC ATCAGCCGCC TTGATGAGGA CCTCACCACC 
CTGGGCCAAA TGAGCAAGCT CTCTGAGAGC CTTGGTTTCC CCCACCAGAG CCTGGACGAT 
GCACTGCGGG ACCTCTCAGC TGCCATGCAC CGGGACCTGT CGGAGAAGCA GGCGCTGTGC 
TACGCGCTTT CCTTCCCGCC AACCAAGCTG GAGCTGTGCG CCACTCGGCC CGAGGGCACC 
GACTCCTACA TTTTTGAGTT CCCTCACCCT GACGCCCGCC TTGGTTTTGA ACAGGCCTTC 
GATGAGGCCA AGAGGAAGCT GGCATCCAGC AAAAGCTGTC TAGACCCTGA GTTCCTGAAG 
GCCATCCCCA TCATGAAAAC CCGCAGTGGC ATGCAGTTCT CCTGTGCGGC TCCCACCCTG 
AACAGCTGCC CGGAGCCCTC GCCTGAGGTA TGGGTCTGCA ACAGCGACGG CTACGTGGGC 
CAGGTGTGCC TGCTGAGCCT GCGCGCCGAG CCGGACGTGG AGGCCTGCAT CGCCGTCTGT 
TCCGCCCGCA TCCTCTGCAT CGGGGCGGTG CCCGGGCTGC AGCCTCGCTG CCACCGGGAG 
CCTCCTCCGT CGCTGAGGAG TCCTCCAGAG ACGGCACCGG AGCCCGCCGG GCCGGAGCTG 
GACGTCGAGG CCGCTGCAGA CGAGGAAGCC GCGACGCTCG CGGAGCCGGG GCCGCAGCCC 
TGCCTTCACA TCTCCATTGC AGGCTCGGGC TTGGAGATGA CGCCGGGCCT CGGCGAGGGT 
GACCCCCGCC CAGAGCTGGT GCCCTTTGAC AGTGACTCTG ACGATGAGTC TTCGCCCAGC 
CCCTCGGGGA CGCTGCAGAG CCAGGCCAGC CGGTCCACCA TCTCCTCCAG CTTTGGCAAT 
GAGGAGACCC CGAGTTCCAA GGAGGCCACG GCAGAGACCA CCAGCTCAGA GGAGGAGCAG 
GAGCCAGGCT TCCTGCCACT GTCTGGCTCC TTTGGGCCTG GTGGTCCCTG CGGCACCAGC 
CCAATGGATG GGAGAGCCCT TCGCCGCTCC AGCCACGGCT CCTTCACCCG GGGCAGCCTT 
GAGGACCTGC TGAGTGTCGA CCCTGAGGCC TACCAGAGCT CCGTGTGGCT GGGCACTGAG 
GATGGCTGTG TCCACGTGTA CCAGTCCTCC GACAGCATCC GTGACCGCAG GAACAGCATG 
AAGCTCCAGC ATGCGGCCTC TGTGACCTGC ATCTTGTATC TGAATAACCA GGTGTTTGTG 
TCTCTGGCCA ATGGAGAGCT TGTGGTCTAC CAAAGGGAAG CAGGCCATTT CTGGGACCCC 
CAGAACTTCA AATCAGTGAC CTTGGGCACC CAGGGGAGCC CCATCACCAA GATGGTATCT 
GTGGGTGGGC GGCTGTGGTG TGGCTGCCAG AACCGAGTCC TTGTCCTGAG CCCTGACACG 
CTGCAGCTGG AGCACATGTT TTACGTGGGT CAGGATTCAA GCCGCTGCGT GGCTTGCATG 
GTGGACTCCA GCCTGGGTGT GTGGGTGACA TTGAAAGGTA GTGCCCACGT GTGTCTCTAC 
CATCCAGACA CCTTTGAGCA GCTGGCAGAA GTAGACGTCA CTCCTCCCGT GCACAGGATG 
CTGGCAGGCT CGGATGCCAT CATCCGGCAG CACAAGGCTG CCTGTCTGCG AATCACAGCG 
CTGCTGGTGT GTGAGGAGCT GCTGTGGGTG GGCACCAGTG CTGGTGTCGT CCTCACCATG 
CCCACTTCGC CCGGTACTGT CAGCTGCCCA CGGGCACCAC TCAGTCCCAC AGGCCTCGGC 
CAGGGACACA CCGGCCACGT CCGCTTCTTG GCTGCAGTCC AGCTGCCAGA TGGCTTCAAC 
CTGCTCTGCC CAACCCCACC ACCTCCCCCA GACACAGGCC CCGAGAAGCT GCCATCACTG 
GAGCACCGGG ACTCCCCTTG GCACCGAGGC CCCGCCCCTG CCAGGCCTAA AATGCTGGTT 
ATCAGTGGAG GTGATGGCTA TGAGGACTTC CGACTCAGCA GTGGGGGCGG CAGCAGCAGT 
GAGACTGTGG GTCGAGACGA CAGCACAAAC CACCTCCTCC TGTGGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016874112.1
CDS	1431..4604
Translation	MGAALSVQDSVRWENHAARGRKSRVLQSKKKRLGDPGGESRRRAARLQGQVEGVAAGKDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Target ORF information:

RefSeq Version	XM_017018623.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017018623.1

ORF Insert Sequence:

ATGGGTGCTG CTTTATCCGT CCAGGACTCC GTGCGTTGGG AAAATCACGC CGCGAGGGGG 
CGCAAGAGCC GCGTACTCCA GAGCAAGAAG AAAAGGCTCG GGGATCCAGG CGGAGAGTCC 
AGGAGAAGAG CCGCCAGACT GCAGGGGCAG GTGGAAGGCG TGGCAGCTGG AAAAGACATG 
CGGAAGCACG TGGCCATGAC CCTGCTGGAC ACAGAGCAGT CGTATGTGGA GTCGCTGCGC 
ACCCTGATGC AGGGCTACAT GCAGCCGCTG AAGCAGCCAG AGAACTCCGT GCTCTGTGAC 
CCTTCACTGG TGGACGAGAT CTTCGACCAG ATCCCCGAGC TCCTGGAGCA CCACGAGCAA 
TTCCTGGAGC AGGTTCGGCA CTGCATGCAG ACCTGGCATG CCCAGCAGAA GGTGGGAGCC 
CTGCTCGTCC AGTCGTTCTC CAAGGATGTC CTAGTAAACA TCTATTCTGC CTATATCGAT 
AACTTCCTCA ATGCAAAGGA TGCTGTGCGT GTGGCCAAGG AGGCGAGGCC TGCCTTTCTC 
AAGTTCCTAG AGCAAAGCAT GCGTGAGAAC AAGGAGAAGC AGGCGCTGTC TGACCTCATG 
ATCAAGCCTG TGCAGCGGAT CCCACGCTAC GAGCTTCTGG TGAAGGACCT CCTGAAGCAT 
ACACCTGAGG ACCACCCGGA CCATCCACTC CTGCTGGAGG CGCAGCGGAA CATCAAGCAG 
GTGGCTGAGC GCATCAACAA GGGTGTGCGG AGTGCCGAGG AGGCGGAGCG CCATGCCCGT 
GTGCTGCAGG AGATAGAGGC TCACATCGAG GGCATGGAGG ATCTCCAGGC CCCTCTGCGG 
CGGTTCCTGA GACAGGAGAT GGTCATTGAA GTGAAGGCGA TCGGTGGCAA GAAGGACCGG 
TCTCTCTTCC TGTTCACGGA CCTCATCGTC TGCACCACTC TGAAGCGAAA GTCAGGCTCC 
CTGCGGCGCA GCTCCATGAG CCTGTACACG GCAGCCAGTG TCATTGACAC AGCCAGCAAG 
TACAAGATGC TGTGGAAGCT GCCGCTGGAA GACGCAGACA TCATCAAAGG GGCATCCCAA 
GCCACCAATC GGGAGAACAT CCAGAAGGCC ATCAGCCGCC TTGATGAGGA CCTCACCACC 
CTGGGCCAAA TGAGCAAGCT CTCTGAGAGC CTTGGTTTCC CCCACCAGAG CCTGGACGAT 
GCACTGCGGG ACCTCTCAGC TGCCATGCAC CGGGACCTGT CGGAGAAGCA GGCGCTGTGC 
TACGCGCTTT CCTTCCCGCC AACCAAGCTG GAGCTGTGCG CCACTCGGCC CGAGGGCACC 
GACTCCTACA TTTTTGAGTT CCCTCACCCT GACGCCCGCC TTGGTTTTGA ACAGGCCTTC 
GATGAGGCCA AGAGGAAGCT GGCATCCAGC AAAAGCTGTC TAGACCCTGA GTTCCTGAAG 
GCCATCCCCA TCATGAAAAC CCGCAGTGGC ATGCAGTTCT CCTGTGCGGC TCCCACCCTG 
AACAGCTGCC CGGAGCCCTC GCCTGAGGTA TGGGTCTGCA ACAGCGACGG CTACGTGGGC 
CAGGTGTGCC TGCTGAGCCT GCGCGCCGAG CCGGACGTGG AGGCCTGCAT CGCCGTCTGT 
TCCGCCCGCA TCCTCTGCAT CGGGGCGGTG CCCGGGCTGC AGCCTCGCTG CCACCGGGAG 
CCTCCTCCGT CGCTGAGGAG TCCTCCAGAG ACGGCACCGG AGCCCGCCGG GCCGGAGCTG 
GACGTCGAGG CCGCTGCAGA CGAGGAAGCC GCGACGCTCG CGGAGCCGGG GCCGCAGCCC 
TGCCTTCACA TCTCCATTGC AGGCTCGGGC TTGGAGATGA CGCCGGGCCT CGGCGAGGGT 
GACCCCCGCC CAGAGCTGGT GCCCTTTGAC AGTGACTCTG ACGATGAGTC TTCGCCCAGC 
CCCTCGGGGA CGCTGCAGAG CCAGGCCAGC CGGTCCACCA TCTCCTCCAG CTTTGGCAAT 
GAGGAGACCC CGAGTTCCAA GGAGGCCACG GCAGAGACCA CCAGCTCAGA GGAGGAGCAG 
GAGCCAGGCT TCCTGCCACT GTCTGGCTCC TTTGGGCCTG GTGGTCCCTG CGGCACCAGC 
CCAATGGATG GGAGAGCCCT TCGCCGCTCC AGCCACGGCT CCTTCACCCG GGGCAGCCTT 
GAGGACCTGC TGAGTGTCGA CCCTGAGGCC TACCAGAGCT CCGTGTGGCT GGGCACTGAG 
GATGGCTGTG TCCACGTGTA CCAGTCCTCC GACAGCATCC GTGACCGCAG GAACAGCATG 
AAGCTCCAGC ATGCGGCCTC TGTGACCTGC ATCTTGTATC TGAATAACCA GGTGTTTGTG 
TCTCTGGCCA ATGGAGAGCT TGTGGTCTAC CAAAGGGAAG CAGGCCATTT CTGGGACCCC 
CAGAACTTCA AATCAGTGAC CTTGGGCACC CAGGGGAGCC CCATCACCAA GATGGTATCT 
GTGGGTGGGC GGCTGTGGTG TGGCTGCCAG AACCGAGTCC TTGTCCTGAG CCCTGACACG 
CTGCAGCTGG AGCACATGTT TTACGTGGGT CAGGATTCAA GCCGCTGCGT GGCTTGCATG 
GTGGACTCCA GCCTGGGTGT GTGGGTGACA TTGAAAGGTA GTGCCCACGT GTGTCTCTAC 
CATCCAGACA CCTTTGAGCA GCTGGCAGAA GTAGACGTCA CTCCTCCCGT GCACAGGATG 
CTGGCAGGCT CGGATGCCAT CATCCGGCAG CACAAGGCTG CCTGTCTGCG AATCACAGCG 
CTGCTGGTGT GTGAGGAGCT GCTGTGGGTG GGCACCAGTG CTGGTGTCGT CCTCACCATG 
CCCACTTCGC CCGGTACTGT CAGCTGCCCA CGGGCACCAC TCAGTCCCAC AGGCCTCGGC 
CAGGGACACA CCGGCCACGT CCGCTTCTTG GCTGCAGTCC AGCTGCCAGA TGGCTTCAAC 
CTGCTCTGCC CAACCCCACC ACCTCCCCCA GACACAGGCC CCGAGAAGCT GCCATCACTG 
GAGCACCGGG ACTCCCCTTG GCACCGAGGC CCCGCCCCTG CCAGGCCTAA AATGCTGGTT 
ATCAGTGGAG GTGATGGCTA TGAGGACTTC CGACTCAGCA GTGGGGGCGG CAGCAGCAGT 
GAGACTGTGG GTCGAGACGA CAGCACAAAC CACCTCCTCC TGTGGAGGGT GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF17 ( NM_014786.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_055601.2 Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.

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CloneID	OHu31458
Clone ID Related Accession (Same CDS sequence)	NM_014786.4 , NM_014786.3
Accession Version	NM_014786.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP002761.3, BC137228.1, AI312037.1, BM684780.1 and AP000562.5. On May 17, 2019 this sequence version replaced NM_014786.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC137228.1, AF378754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000263674.4/ ENSP00000263674.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACG GGGCACCCCG GCCCCAGCTT TACCGCAGCG TCTCGTTCAA GCTGCTGGAG 
CGCTGGAGCG GCGGCCCCGG GCTGAGGGAG GAGGACACGG ACACCCCCGG CTTGAGGCGA 
CGCGCCTCGT GCCGGCCGAC CACGGCTGCC CGGGGCCAGC CCTCTCGGCG CGTGTCCAAG 
CTGGCGTCTG GGCCCCTGGC CGCCCCCGCG CAGCCGCGCC CGCTCCGCAG CCTCTCGCCG 
TCGGTTCGCC AGCTCTCCCG GCGCTTCGAC GCGCCGCGTC TGGACGACGG CTCCGCTGGG 
ACCCGAGACG GAGGCGTCTT ACCCGCGGCC GCGGAAGAAG CGGCCGAGGG CCCAGCGCGA 
GGAGCCTGGC CCAGCGTCAC CGAGATGCGC AAGCTCTTCG GCGGTCCTGG CTCCAGGAGG 
CCCAGCGCCG ACTCTGAATC CCCAGGAACG CCCAGCCCCG ACGGTGCCGC GTGGGAGCCT 
CCGGCTCGGG AGTCGCGGCA GCCACCGACG CCACCCCCTC GGACATGCTT CCCCCTGGCG 
GGTCTGCGTT CGGCGCGGCC CCTGACCGGG CCGGAGACCG AAGGGAGGCT GCGCCGGCCG 
CAGCAGCAAC AGGAGCGGGC GCAGCGTCCA GCGGATGGTT TACATTCTTG GCATATCTTC 
TCCCAACCGC AGGCCGGGGC CCGGGCCTCC TGCTCCTCCT CCTCCATCGC CGCCTCCTAT 
CCTGTCAGCC GCAGTCGTGC TGCCAGCTCC AGCGAGGAGG AAGAGGAGGG CCCGCCGCAG 
CTGCCTGGAG CCCAGAGTCC GGCCTACCAC GGCGGCCACT CCTCGGGCAG TGACGACGAC 
CGAGACGGTG AGGGCGGCCA CCGCTGGGGA GGGAGGCCCG GGCTCAGGCC TGGAAGCTCC 
CTATTGGATC AGGACTGCAG GCCTGACAGT GATGGGTTAA ATCTAAGCAG CATGAACTCA 
GCAGGGGTTT CTGGGAGCCC TGAGCCCCCA ACATCTCCAA GAGCCCCTAG AGAAGAAGGA 
CTCCGGGAGT GGGGTAGTGG CTCTCCGCCC TGCGTCCCAG GTCCCCAGGA GGGACTTCGG 
CCTATGTCTG ACTCTGTGGG AGGAGCTTTC CGTGTGGCCA AGGTGAGCTT TCCCTCGTAC 
CTGGCCAGCC CCGCAGGCTC CCGCGGTAGC AGCCGTTATT CCAGCACGGA GACCCTCAAG 
GACGACGACC TATGGTCTAG TAGGGGTTCT GGGGGCTGGG GCGTGTACCG CTCCCCTAGC 
TTTGGAGCTG GGGAAGGGCT CCTGCGGTCC CAGGCTCGAA CCCGTGCCAA AGGACCTGGA 
GGCACCTCTA GGGCATTGAG GGATGGAGGA TTTGAGCCTG AAAAGAGTCG ACAGCGGAAG 
TCCCTGTCAA ATCCAGATAT CGCCTCAGAG ACCCTGACGC TTCTCAGTTT CCTGCGCTCA 
GACCTTTCAG AGCTGAGGGT CCGAAAACCT GGTGGGAGCT CCGGGGACCG TGGAAGCAAC 
CCCCTAGATG GCAGAGACTC ACCATCCGCA GGTGGCCCTG TGGGGCAACT TGAACCCATA 
CCCATCCCAG CCCCAGCATC ACCTGGCACG CGCCCCACAC TCAAGGACTT GACAGCCACT 
CTGCGGAGAG CAAAGTCATT CACCTGCTCT GAGAAGCCCA TGGCCCGCCG CCTGCCCCGC 
ACCAGTGCTC TGAAGTCCAG CTCCTCCGAG CTCCTGCTCA CAGGCCCTGG TGCCGAGGAG 
GATCCGCTGC CCCTCATCGT CCAGGACCAA TATGTGCAGG AGGCCCGCCA GGTTTTTGAG 
AAGATCCAGC GCATGGGTGC CCAACAAGAT GATGGAAGCG ATGCCCCCCC TGGAAGCCCT 
GACTGGGCAG GGGATGTGAC CCGAGGGCAG CGGTCCCAGG AGGAGCTCTC AGGCCCTGAG 
TCCAGTCTGA CAGATGAAGG CATTGGGGCA GACCCTGAGC CTCCTGTTGC AGCATTTTGC 
GGCCTGGGTA CCACAGGGAT GTGGCGACCT CTTTCCTCAT CCTCGGCCCA GACGAACCAC 
CATGGCCCTG GGACTGAGGA CAGTCTGGGC GGGTGGGCCC TGGTGTCGCC TGAGACCCCT 
CCCACACCAG GTGCCCTCCG CCGACGACGC AAAGTCCCAC CTTCAGGTTC TGGTGGGAGC 
GAATTGAGCA ATGGGGAGGC AGGGGAGGCC TACAGGTCCC TGAGTGACCC AATTCCTCAG 
CGCCACCGGG CTGCCACCTC TGAAGAGCCT ACTGGGTTCT CTGTGGACAG CAACCTCCTG 
GGCTCACTGA GCCCCAAGAC AGGGCTCCCT GCCACCTCAG CCATGGATGA GGGCTTGACC 
AGTGGTCACA GTGACTGGTC TGTGGGCAGT GAAGAGAGCA AGGGATATCA GGAGGTTATT 
CAGAGCATAG TTCAGGGGCC TGGCACCCTG GGGCGTGTGG TGGACGACAG GATTGCTGGC 
AAAGCCCCCA AGAAGAAATC CCTGAGTGAC CCCAGCCGCC GTGGGGAGCT GGCTGGGCCT 
GGATTCGAGG GCCCTGGAGG GGAGCCCATC CGAGAAGTTG AGCCCATGCT GCCTCCATCC 
AGCAGCGAGC CCATCCTTGT AGAGCAGCGG GCAGAGCCAG AAGAACCTGG TGCCACCAGG 
AGCCGGGCAC AGTCTGAAAG GGCCCTACCT GAGGCTCTGC CTCCCCCTGC CACTGCCCAC 
CGAAACTTTC ACCTTGACCC CAAGCTGGCT GACATTCTGT CCCCGAGGCT AATCCGCCGA 
GGCTCCAAGA AGCGCCCAGC TCGGAGTAGT CACCAGGAGC TTCGGAGAGA CGAGGGCAGT 
CAGGACCAGA CTGGCAGCCT GTCTCGGGCC CGGCCCTCCT CCAGACACGT TCGCCATGCC 
AGTGTGCCCG CCACATTTAT GCCTATTGTG GTGCCTGAGC CACCAACTTC TGTTGGTCCC 
CCTGTGGCTG TGCCAGAACC CATAGGCTTC CCTACCCGAG CCCATCCCAC GTTGCAGGCA 
CCATCGCTCG AGGACGTCAC CAAGCAGTAC ATGCTGAACC TGCACTCCGG TGAGGTCCCT 
GCCCCAGTGC CAGTGGACAT GCCCTGCTTG CCTCTGGCTG CACCGCCCTC TGCTGAGGCC 
AAGCCCCCTG AGGCAGCTCG GCCTGCAGAT GAGCCTACCC CTGCCAGCAA GTGCTGCAGC 
AAGCCACAGG TGGACATGCG GAAGCACGTG GCCATGACCC TGCTGGACAC AGAGCAGTCG 
TATGTGGAGT CGCTGCGCAC CCTGATGCAG GGCTACATGC AGCCGCTGAA GCAGCCAGAG 
AACTCCGTGC TCTGTGACCC TTCACTGGTG GACGAGATCT TCGACCAGAT CCCCGAGCTC 
CTGGAGCACC ACGAGCAATT CCTGGAGCAG GTTCGGCACT GCATGCAGAC CTGGCATGCC 
CAGCAGAAGG TGGGAGCCCT GCTCGTCCAG TCGTTCTCCA AGGATGTCCT AGTAAACATC 
TATTCTGCCT ATATCGATAA CTTCCTCAAT GCAAAGGATG CTGTGCGTGT GGCCAAGGAG 
GCGAGGCCTG CCTTTCTCAA GTTCCTAGAG CAAAGCATGC GTGAGAACAA GGAGAAGCAG 
GCGCTGTCTG ACCTCATGAT CAAGCCTGTG CAGCGGATCC CACGCTACGA GCTTCTGGTG 
AAGGACCTCC TGAAGCATAC ACCTGAGGAC CACCCGGACC ATCCACTCCT GCTGGAGGCG 
CAGCGGAACA TCAAGCAGGT GGCTGAGCGC ATCAACAAGG GTGTGCGGAG TGCCGAGGAG 
GCGGAGCGCC ATGCCCGTGT GCTGCAGGAG ATAGAGGCTC ACATCGAGGG CATGGAGGAT 
CTCCAGGCCC CTCTGCGGCG GTTCCTGAGA CAGGAGATGG TCATTGAAGT GAAGGCGATC 
GGTGGCAAGA AGGACCGGTC TCTCTTCCTG TTCACGGACC TCATCGTCTG CACCACTCTG 
AAGCGAAAGT CAGGCTCCCT GCGGCGCAGC TCCATGAGCC TGTACACGGC AGCCAGTGTC 
ATTGACACAG CCAGCAAGTA CAAGATGCTG TGGAAGCTGC CGCTGGAAGA CGCAGACATC 
ATCAAAGGGG CATCCCAAGC CACCAATCGG GAGAACATCC AGAAGGCCAT CAGCCGCCTT 
GATGAGGACC TCACCACCCT GGGCCAAATG AGCAAGCTCT CTGAGAGCCT TGGTTTCCCC 
CACCAGAGCC TGGACGATGC ACTGCGGGAC CTCTCAGCTG CCATGCACCG GGACCTGTCG 
GAGAAGCAGG CGCTGTGCTA CGCGCTTTCC TTCCCGCCAA CCAAGCTGGA GCTGTGCGCC 
ACTCGGCCCG AGGGCACCGA CTCCTACATT TTTGAGTTCC CTCACCCTGA CGCCCGCCTT 
GGTTTTGAAC AGGCCTTCGA TGAGGCCAAG AGGAAGCTGG CATCCAGCAA AAGCTGTCTA 
GACCCTGAGT TCCTGAAGGC CATCCCCATC ATGAAAACCC GCAGTGGCAT GCAGTTCTCC 
TGTGCGGCTC CCACCCTGAA CAGCTGCCCG GAGCCCTCGC CTGAGGTATG GGTCTGCAAC 
AGCGACGGCT ACGTGGGCCA GGTGTGCCTG CTGAGCCTGC GCGCCGAGCC GGACGTGGAG 
GCCTGCATCG CCGTCTGTTC CGCCCGCATC CTCTGCATCG GGGCGGTGCC CGGGCTGCAG 
CCTCGCTGCC ACCGGGAGCC TCCTCCGTCG CTGAGGAGTC CTCCAGAGAC GGCACCGGAG 
CCCGCCGGGC CGGAGCTGGA CGTCGAGGCC GCTGCAGACG AGGAAGCCGC GACGCTCGCG 
GAGCCGGGGC CGCAGCCCTG CCTTCACATC TCCATTGCAG GCTCGGGCTT GGAGATGACG 
CCGGGCCTCG GCGAGGGTGA CCCCCGCCCA GAGCTGGTGC CCTTTGACAG TGACTCTGAC 
GATGAGTCTT CGCCCAGCCC CTCGGGGACG CTGCAGAGCC AGGCCAGCCG GTCCACCATC 
TCCTCCAGCT TTGGCAATGA GGAGACCCCG AGTTCCAAGG AGGCCACGGC AGAGACCACC 
AGCTCAGAGG AGGAGCAGGA GCCAGGCTTC CTGCCACTGT CTGGCTCCTT TGGGCCTGGT 
GGTCCCTGCG GCACCAGCCC AATGGATGGG AGAGCCCTTC GCCGCTCCAG CCACGGCTCC 
TTCACCCGGG GCAGCCTTGA GGACCTGCTG AGTGTCGACC CTGAGGCCTA CCAGAGCTCC 
GTGTGGCTGG GCACTGAGGA TGGCTGTGTC CACGTGTACC AGTCCTCCGA CAGCATCCGT 
GACCGCAGGA ACAGCATGAA GCTCCAGCAT GCGGCCTCTG TGACCTGCAT CTTGTATCTG 
AATAACCAGG TGTTTGTGTC TCTGGCCAAT GGAGAGCTTG TGGTCTACCA AAGGGAAGCA 
GGCCATTTCT GGGACCCCCA GAACTTCAAA TCAGTGACCT TGGGCACCCA GGGGAGCCCC 
ATCACCAAGA TGGTATCTGT GGGTGGGCGG CTGTGGTGTG GCTGCCAGAA CCGAGTCCTT 
GTCCTGAGCC CTGACACGCT GCAGCTGGAG CACATGTTTT ACGTGGGTCA GGATTCAAGC 
CGCTGCGTGG CTTGCATGGT GGACTCCAGC CTGGGTGTGT GGGTGACATT GAAAGGTAGT 
GCCCACGTGT GTCTCTACCA TCCAGACACC TTTGAGCAGC TGGCAGAAGT AGACGTCACT 
CCTCCCGTGC ACAGGATGCT GGCAGGCTCG GATGCCATCA TCCGGCAGCA CAAGGCTGCC 
TGTCTGCGAA TCACAGCGCT GCTGGTGTGT GAGGAGCTGC TGTGGGTGGG CACCAGTGCT 
GGTGTCGTCC TCACCATGCC CACTTCGCCC GGTACTGTCA GCTGCCCACG GGCACCACTC 
AGTCCCACAG GCCTCGGCCA GGGACACACC GGCCACGTCC GCTTCTTGGC TGCAGTCCAG 
CTGCCAGATG GCTTCAACCT GCTCTGCCCA ACCCCACCAC CTCCCCCAGA CACAGGCCCC 
GAGAAGCTGC CATCACTGGA GCACCGGGAC TCCCCTTGGC ACCGAGGCCC CGCCCCTGCC 
AGGCCTAAAA TGCTGGTTAT CAGTGGAGGT GATGGCTATG AGGACTTCCG ACTCAGCAGT 
GGGGGCGGCA GCAGCAGTGA GACTGTGGGT CGAGACGACA GCACAAACCA CCTCCTCCTG 
TGGAGGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055601.2
CDS	364..6555
Translation	MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSKLASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPARGAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLAGLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASYPVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSSLLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLRPMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPSFGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGSELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Target ORF information:

RefSeq Version	NM_014786.4
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014786.4

ORF Insert Sequence:

ATGGCGGACG GGGCACCCCG GCCCCAGCTT TACCGCAGCG TCTCGTTCAA GCTGCTGGAG 
CGCTGGAGCG GCGGCCCCGG GCTGAGGGAG GAGGACACGG ACACCCCCGG CTTGAGGCGA 
CGCGCCTCGT GCCGGCCGAC CACGGCTGCC CGGGGCCAGC CCTCTCGGCG CGTGTCCAAG 
CTGGCGTCTG GGCCCCTGGC CGCCCCCGCG CAGCCGCGCC CGCTCCGCAG CCTCTCGCCG 
TCGGTTCGCC AGCTCTCCCG GCGCTTCGAC GCGCCGCGTC TGGACGACGG CTCCGCTGGG 
ACCCGAGACG GAGGCGTCTT ACCCGCGGCC GCGGAAGAAG CGGCCGAGGG CCCAGCGCGA 
GGAGCCTGGC CCAGCGTCAC CGAGATGCGC AAGCTCTTCG GCGGTCCTGG CTCCAGGAGG 
CCCAGCGCCG ACTCTGAATC CCCAGGAACG CCCAGCCCCG ACGGTGCCGC GTGGGAGCCT 
CCGGCTCGGG AGTCGCGGCA GCCACCGACG CCACCCCCTC GGACATGCTT CCCCCTGGCG 
GGTCTGCGTT CGGCGCGGCC CCTGACCGGG CCGGAGACCG AAGGGAGGCT GCGCCGGCCG 
CAGCAGCAAC AGGAGCGGGC GCAGCGTCCA GCGGATGGTT TACATTCTTG GCATATCTTC 
TCCCAACCGC AGGCCGGGGC CCGGGCCTCC TGCTCCTCCT CCTCCATCGC CGCCTCCTAT 
CCTGTCAGCC GCAGTCGTGC TGCCAGCTCC AGCGAGGAGG AAGAGGAGGG CCCGCCGCAG 
CTGCCTGGAG CCCAGAGTCC GGCCTACCAC GGCGGCCACT CCTCGGGCAG TGACGACGAC 
CGAGACGGTG AGGGCGGCCA CCGCTGGGGA GGGAGGCCCG GGCTCAGGCC TGGAAGCTCC 
CTATTGGATC AGGACTGCAG GCCTGACAGT GATGGGTTAA ATCTAAGCAG CATGAACTCA 
GCAGGGGTTT CTGGGAGCCC TGAGCCCCCA ACATCTCCAA GAGCCCCTAG AGAAGAAGGA 
CTCCGGGAGT GGGGTAGTGG CTCTCCGCCC TGCGTCCCAG GTCCCCAGGA GGGACTTCGG 
CCTATGTCTG ACTCTGTGGG AGGAGCTTTC CGTGTGGCCA AGGTGAGCTT TCCCTCGTAC 
CTGGCCAGCC CCGCAGGCTC CCGCGGTAGC AGCCGTTATT CCAGCACGGA GACCCTCAAG 
GACGACGACC TATGGTCTAG TAGGGGTTCT GGGGGCTGGG GCGTGTACCG CTCCCCTAGC 
TTTGGAGCTG GGGAAGGGCT CCTGCGGTCC CAGGCTCGAA CCCGTGCCAA AGGACCTGGA 
GGCACCTCTA GGGCATTGAG GGATGGAGGA TTTGAGCCTG AAAAGAGTCG ACAGCGGAAG 
TCCCTGTCAA ATCCAGATAT CGCCTCAGAG ACCCTGACGC TTCTCAGTTT CCTGCGCTCA 
GACCTTTCAG AGCTGAGGGT CCGAAAACCT GGTGGGAGCT CCGGGGACCG TGGAAGCAAC 
CCCCTAGATG GCAGAGACTC ACCATCCGCA GGTGGCCCTG TGGGGCAACT TGAACCCATA 
CCCATCCCAG CCCCAGCATC ACCTGGCACG CGCCCCACAC TCAAGGACTT GACAGCCACT 
CTGCGGAGAG CAAAGTCATT CACCTGCTCT GAGAAGCCCA TGGCCCGCCG CCTGCCCCGC 
ACCAGTGCTC TGAAGTCCAG CTCCTCCGAG CTCCTGCTCA CAGGCCCTGG TGCCGAGGAG 
GATCCGCTGC CCCTCATCGT CCAGGACCAA TATGTGCAGG AGGCCCGCCA GGTTTTTGAG 
AAGATCCAGC GCATGGGTGC CCAACAAGAT GATGGAAGCG ATGCCCCCCC TGGAAGCCCT 
GACTGGGCAG GGGATGTGAC CCGAGGGCAG CGGTCCCAGG AGGAGCTCTC AGGCCCTGAG 
TCCAGTCTGA CAGATGAAGG CATTGGGGCA GACCCTGAGC CTCCTGTTGC AGCATTTTGC 
GGCCTGGGTA CCACAGGGAT GTGGCGACCT CTTTCCTCAT CCTCGGCCCA GACGAACCAC 
CATGGCCCTG GGACTGAGGA CAGTCTGGGC GGGTGGGCCC TGGTGTCGCC TGAGACCCCT 
CCCACACCAG GTGCCCTCCG CCGACGACGC AAAGTCCCAC CTTCAGGTTC TGGTGGGAGC 
GAATTGAGCA ATGGGGAGGC AGGGGAGGCC TACAGGTCCC TGAGTGACCC AATTCCTCAG 
CGCCACCGGG CTGCCACCTC TGAAGAGCCT ACTGGGTTCT CTGTGGACAG CAACCTCCTG 
GGCTCACTGA GCCCCAAGAC AGGGCTCCCT GCCACCTCAG CCATGGATGA GGGCTTGACC 
AGTGGTCACA GTGACTGGTC TGTGGGCAGT GAAGAGAGCA AGGGATATCA GGAGGTTATT 
CAGAGCATAG TTCAGGGGCC TGGCACCCTG GGGCGTGTGG TGGACGACAG GATTGCTGGC 
AAAGCCCCCA AGAAGAAATC CCTGAGTGAC CCCAGCCGCC GTGGGGAGCT GGCTGGGCCT 
GGATTCGAGG GCCCTGGAGG GGAGCCCATC CGAGAAGTTG AGCCCATGCT GCCTCCATCC 
AGCAGCGAGC CCATCCTTGT AGAGCAGCGG GCAGAGCCAG AAGAACCTGG TGCCACCAGG 
AGCCGGGCAC AGTCTGAAAG GGCCCTACCT GAGGCTCTGC CTCCCCCTGC CACTGCCCAC 
CGAAACTTTC ACCTTGACCC CAAGCTGGCT GACATTCTGT CCCCGAGGCT AATCCGCCGA 
GGCTCCAAGA AGCGCCCAGC TCGGAGTAGT CACCAGGAGC TTCGGAGAGA CGAGGGCAGT 
CAGGACCAGA CTGGCAGCCT GTCTCGGGCC CGGCCCTCCT CCAGACACGT TCGCCATGCC 
AGTGTGCCCG CCACATTTAT GCCTATTGTG GTGCCTGAGC CACCAACTTC TGTTGGTCCC 
CCTGTGGCTG TGCCAGAACC CATAGGCTTC CCTACCCGAG CCCATCCCAC GTTGCAGGCA 
CCATCGCTCG AGGACGTCAC CAAGCAGTAC ATGCTGAACC TGCACTCCGG TGAGGTCCCT 
GCCCCAGTGC CAGTGGACAT GCCCTGCTTG CCTCTGGCTG CACCGCCCTC TGCTGAGGCC 
AAGCCCCCTG AGGCAGCTCG GCCTGCAGAT GAGCCTACCC CTGCCAGCAA GTGCTGCAGC 
AAGCCACAGG TGGACATGCG GAAGCACGTG GCCATGACCC TGCTGGACAC AGAGCAGTCG 
TATGTGGAGT CGCTGCGCAC CCTGATGCAG GGCTACATGC AGCCGCTGAA GCAGCCAGAG 
AACTCCGTGC TCTGTGACCC TTCACTGGTG GACGAGATCT TCGACCAGAT CCCCGAGCTC 
CTGGAGCACC ACGAGCAATT CCTGGAGCAG GTTCGGCACT GCATGCAGAC CTGGCATGCC 
CAGCAGAAGG TGGGAGCCCT GCTCGTCCAG TCGTTCTCCA AGGATGTCCT AGTAAACATC 
TATTCTGCCT ATATCGATAA CTTCCTCAAT GCAAAGGATG CTGTGCGTGT GGCCAAGGAG 
GCGAGGCCTG CCTTTCTCAA GTTCCTAGAG CAAAGCATGC GTGAGAACAA GGAGAAGCAG 
GCGCTGTCTG ACCTCATGAT CAAGCCTGTG CAGCGGATCC CACGCTACGA GCTTCTGGTG 
AAGGACCTCC TGAAGCATAC ACCTGAGGAC CACCCGGACC ATCCACTCCT GCTGGAGGCG 
CAGCGGAACA TCAAGCAGGT GGCTGAGCGC ATCAACAAGG GTGTGCGGAG TGCCGAGGAG 
GCGGAGCGCC ATGCCCGTGT GCTGCAGGAG ATAGAGGCTC ACATCGAGGG CATGGAGGAT 
CTCCAGGCCC CTCTGCGGCG GTTCCTGAGA CAGGAGATGG TCATTGAAGT GAAGGCGATC 
GGTGGCAAGA AGGACCGGTC TCTCTTCCTG TTCACGGACC TCATCGTCTG CACCACTCTG 
AAGCGAAAGT CAGGCTCCCT GCGGCGCAGC TCCATGAGCC TGTACACGGC AGCCAGTGTC 
ATTGACACAG CCAGCAAGTA CAAGATGCTG TGGAAGCTGC CGCTGGAAGA CGCAGACATC 
ATCAAAGGGG CATCCCAAGC CACCAATCGG GAGAACATCC AGAAGGCCAT CAGCCGCCTT 
GATGAGGACC TCACCACCCT GGGCCAAATG AGCAAGCTCT CTGAGAGCCT TGGTTTCCCC 
CACCAGAGCC TGGACGATGC ACTGCGGGAC CTCTCAGCTG CCATGCACCG GGACCTGTCG 
GAGAAGCAGG CGCTGTGCTA CGCGCTTTCC TTCCCGCCAA CCAAGCTGGA GCTGTGCGCC 
ACTCGGCCCG AGGGCACCGA CTCCTACATT TTTGAGTTCC CTCACCCTGA CGCCCGCCTT 
GGTTTTGAAC AGGCCTTCGA TGAGGCCAAG AGGAAGCTGG CATCCAGCAA AAGCTGTCTA 
GACCCTGAGT TCCTGAAGGC CATCCCCATC ATGAAAACCC GCAGTGGCAT GCAGTTCTCC 
TGTGCGGCTC CCACCCTGAA CAGCTGCCCG GAGCCCTCGC CTGAGGTATG GGTCTGCAAC 
AGCGACGGCT ACGTGGGCCA GGTGTGCCTG CTGAGCCTGC GCGCCGAGCC GGACGTGGAG 
GCCTGCATCG CCGTCTGTTC CGCCCGCATC CTCTGCATCG GGGCGGTGCC CGGGCTGCAG 
CCTCGCTGCC ACCGGGAGCC TCCTCCGTCG CTGAGGAGTC CTCCAGAGAC GGCACCGGAG 
CCCGCCGGGC CGGAGCTGGA CGTCGAGGCC GCTGCAGACG AGGAAGCCGC GACGCTCGCG 
GAGCCGGGGC CGCAGCCCTG CCTTCACATC TCCATTGCAG GCTCGGGCTT GGAGATGACG 
CCGGGCCTCG GCGAGGGTGA CCCCCGCCCA GAGCTGGTGC CCTTTGACAG TGACTCTGAC 
GATGAGTCTT CGCCCAGCCC CTCGGGGACG CTGCAGAGCC AGGCCAGCCG GTCCACCATC 
TCCTCCAGCT TTGGCAATGA GGAGACCCCG AGTTCCAAGG AGGCCACGGC AGAGACCACC 
AGCTCAGAGG AGGAGCAGGA GCCAGGCTTC CTGCCACTGT CTGGCTCCTT TGGGCCTGGT 
GGTCCCTGCG GCACCAGCCC AATGGATGGG AGAGCCCTTC GCCGCTCCAG CCACGGCTCC 
TTCACCCGGG GCAGCCTTGA GGACCTGCTG AGTGTCGACC CTGAGGCCTA CCAGAGCTCC 
GTGTGGCTGG GCACTGAGGA TGGCTGTGTC CACGTGTACC AGTCCTCCGA CAGCATCCGT 
GACCGCAGGA ACAGCATGAA GCTCCAGCAT GCGGCCTCTG TGACCTGCAT CTTGTATCTG 
AATAACCAGG TGTTTGTGTC TCTGGCCAAT GGAGAGCTTG TGGTCTACCA AAGGGAAGCA 
GGCCATTTCT GGGACCCCCA GAACTTCAAA TCAGTGACCT TGGGCACCCA GGGGAGCCCC 
ATCACCAAGA TGGTATCTGT GGGTGGGCGG CTGTGGTGTG GCTGCCAGAA CCGAGTCCTT 
GTCCTGAGCC CTGACACGCT GCAGCTGGAG CACATGTTTT ACGTGGGTCA GGATTCAAGC 
CGCTGCGTGG CTTGCATGGT GGACTCCAGC CTGGGTGTGT GGGTGACATT GAAAGGTAGT 
GCCCACGTGT GTCTCTACCA TCCAGACACC TTTGAGCAGC TGGCAGAAGT AGACGTCACT 
CCTCCCGTGC ACAGGATGCT GGCAGGCTCG GATGCCATCA TCCGGCAGCA CAAGGCTGCC 
TGTCTGCGAA TCACAGCGCT GCTGGTGTGT GAGGAGCTGC TGTGGGTGGG CACCAGTGCT 
GGTGTCGTCC TCACCATGCC CACTTCGCCC GGTACTGTCA GCTGCCCACG GGCACCACTC 
AGTCCCACAG GCCTCGGCCA GGGACACACC GGCCACGTCC GCTTCTTGGC TGCAGTCCAG 
CTGCCAGATG GCTTCAACCT GCTCTGCCCA ACCCCACCAC CTCCCCCAGA CACAGGCCCC 
GAGAAGCTGC CATCACTGGA GCACCGGGAC TCCCCTTGGC ACCGAGGCCC CGCCCCTGCC 
AGGCCTAAAA TGCTGGTTAT CAGTGGAGGT GATGGCTATG AGGACTTCCG ACTCAGCAGT 
GGGGGCGGCA GCAGCAGTGA GACTGTGGGT CGAGACGACA GCACAAACCA CCTCCTCCTG 
TGGAGGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ARHGEF17 ( NM_014786.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055601.2 Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.

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CloneID	OHu31458
Clone ID Related Accession (Same CDS sequence)	NM_014786.4 , NM_014786.3
Accession Version	NM_014786.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 6192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	rho guanine nucleotide exchange factor 17
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC137228.1, AI312037.1 and BM684780.1. On Jan 22, 2009 this sequence version replaced NM_014786.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC137228.1, AF378754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGACG GGGCACCCCG GCCCCAGCTT TACCGCAGCG TCTCGTTCAA GCTGCTGGAG 
CGCTGGAGCG GCGGCCCCGG GCTGAGGGAG GAGGACACGG ACACCCCCGG CTTGAGGCGA 
CGCGCCTCGT GCCGGCCGAC CACGGCTGCC CGGGGCCAGC CCTCTCGGCG CGTGTCCAAG 
CTGGCGTCTG GGCCCCTGGC CGCCCCCGCG CAGCCGCGCC CGCTCCGCAG CCTCTCGCCG 
TCGGTTCGCC AGCTCTCCCG GCGCTTCGAC GCGCCGCGTC TGGACGACGG CTCCGCTGGG 
ACCCGAGACG GAGGCGTCTT ACCCGCGGCC GCGGAAGAAG CGGCCGAGGG CCCAGCGCGA 
GGAGCCTGGC CCAGCGTCAC CGAGATGCGC AAGCTCTTCG GCGGTCCTGG CTCCAGGAGG 
CCCAGCGCCG ACTCTGAATC CCCAGGAACG CCCAGCCCCG ACGGTGCCGC GTGGGAGCCT 
CCGGCTCGGG AGTCGCGGCA GCCACCGACG CCACCCCCTC GGACATGCTT CCCCCTGGCG 
GGTCTGCGTT CGGCGCGGCC CCTGACCGGG CCGGAGACCG AAGGGAGGCT GCGCCGGCCG 
CAGCAGCAAC AGGAGCGGGC GCAGCGTCCA GCGGATGGTT TACATTCTTG GCATATCTTC 
TCCCAACCGC AGGCCGGGGC CCGGGCCTCC TGCTCCTCCT CCTCCATCGC CGCCTCCTAT 
CCTGTCAGCC GCAGTCGTGC TGCCAGCTCC AGCGAGGAGG AAGAGGAGGG CCCGCCGCAG 
CTGCCTGGAG CCCAGAGTCC GGCCTACCAC GGCGGCCACT CCTCGGGCAG TGACGACGAC 
CGAGACGGTG AGGGCGGCCA CCGCTGGGGA GGGAGGCCCG GGCTCAGGCC TGGAAGCTCC 
CTATTGGATC AGGACTGCAG GCCTGACAGT GATGGGTTAA ATCTAAGCAG CATGAACTCA 
GCAGGGGTTT CTGGGAGCCC TGAGCCCCCA ACATCTCCAA GAGCCCCTAG AGAAGAAGGA 
CTCCGGGAGT GGGGTAGTGG CTCTCCGCCC TGCGTCCCAG GTCCCCAGGA GGGACTTCGG 
CCTATGTCTG ACTCTGTGGG AGGAGCTTTC CGTGTGGCCA AGGTGAGCTT TCCCTCGTAC 
CTGGCCAGCC CCGCAGGCTC CCGCGGTAGC AGCCGTTATT CCAGCACGGA GACCCTCAAG 
GACGACGACC TATGGTCTAG TAGGGGTTCT GGGGGCTGGG GCGTGTACCG CTCCCCTAGC 
TTTGGAGCTG GGGAAGGGCT CCTGCGGTCC CAGGCTCGAA CCCGTGCCAA AGGACCTGGA 
GGCACCTCTA GGGCATTGAG GGATGGAGGA TTTGAGCCTG AAAAGAGTCG ACAGCGGAAG 
TCCCTGTCAA ATCCAGATAT CGCCTCAGAG ACCCTGACGC TTCTCAGTTT CCTGCGCTCA 
GACCTTTCAG AGCTGAGGGT CCGAAAACCT GGTGGGAGCT CCGGGGACCG TGGAAGCAAC 
CCCCTAGATG GCAGAGACTC ACCATCCGCA GGTGGCCCTG TGGGGCAACT TGAACCCATA 
CCCATCCCAG CCCCAGCATC ACCTGGCACG CGCCCCACAC TCAAGGACTT GACAGCCACT 
CTGCGGAGAG CAAAGTCATT CACCTGCTCT GAGAAGCCCA TGGCCCGCCG CCTGCCCCGC 
ACCAGTGCTC TGAAGTCCAG CTCCTCCGAG CTCCTGCTCA CAGGCCCTGG TGCCGAGGAG 
GATCCGCTGC CCCTCATCGT CCAGGACCAA TATGTGCAGG AGGCCCGCCA GGTTTTTGAG 
AAGATCCAGC GCATGGGTGC CCAACAAGAT GATGGAAGCG ATGCCCCCCC TGGAAGCCCT 
GACTGGGCAG GGGATGTGAC CCGAGGGCAG CGGTCCCAGG AGGAGCTCTC AGGCCCTGAG 
TCCAGTCTGA CAGATGAAGG CATTGGGGCA GACCCTGAGC CTCCTGTTGC AGCATTTTGC 
GGCCTGGGTA CCACAGGGAT GTGGCGACCT CTTTCCTCAT CCTCGGCCCA GACGAACCAC 
CATGGCCCTG GGACTGAGGA CAGTCTGGGC GGGTGGGCCC TGGTGTCGCC TGAGACCCCT 
CCCACACCAG GTGCCCTCCG CCGACGACGC AAAGTCCCAC CTTCAGGTTC TGGTGGGAGC 
GAATTGAGCA ATGGGGAGGC AGGGGAGGCC TACAGGTCCC TGAGTGACCC AATTCCTCAG 
CGCCACCGGG CTGCCACCTC TGAAGAGCCT ACTGGGTTCT CTGTGGACAG CAACCTCCTG 
GGCTCACTGA GCCCCAAGAC AGGGCTCCCT GCCACCTCAG CCATGGATGA GGGCTTGACC 
AGTGGTCACA GTGACTGGTC TGTGGGCAGT GAAGAGAGCA AGGGATATCA GGAGGTTATT 
CAGAGCATAG TTCAGGGGCC TGGCACCCTG GGGCGTGTGG TGGACGACAG GATTGCTGGC 
AAAGCCCCCA AGAAGAAATC CCTGAGTGAC CCCAGCCGCC GTGGGGAGCT GGCTGGGCCT 
GGATTCGAGG GCCCTGGAGG GGAGCCCATC CGAGAAGTTG AGCCCATGCT GCCTCCATCC 
AGCAGCGAGC CCATCCTTGT AGAGCAGCGG GCAGAGCCAG AAGAACCTGG TGCCACCAGG 
AGCCGGGCAC AGTCTGAAAG GGCCCTACCT GAGGCTCTGC CTCCCCCTGC CACTGCCCAC 
CGAAACTTTC ACCTTGACCC CAAGCTGGCT GACATTCTGT CCCCGAGGCT AATCCGCCGA 
GGCTCCAAGA AGCGCCCAGC TCGGAGTAGT CACCAGGAGC TTCGGAGAGA CGAGGGCAGT 
CAGGACCAGA CTGGCAGCCT GTCTCGGGCC CGGCCCTCCT CCAGACACGT TCGCCATGCC 
AGTGTGCCCG CCACATTTAT GCCTATTGTG GTGCCTGAGC CACCAACTTC TGTTGGTCCC 
CCTGTGGCTG TGCCAGAACC CATAGGCTTC CCTACCCGAG CCCATCCCAC GTTGCAGGCA 
CCATCGCTCG AGGACGTCAC CAAGCAGTAC ATGCTGAACC TGCACTCCGG TGAGGTCCCT 
GCCCCAGTGC CAGTGGACAT GCCCTGCTTG CCTCTGGCTG CACCGCCCTC TGCTGAGGCC 
AAGCCCCCTG AGGCAGCTCG GCCTGCAGAT GAGCCTACCC CTGCCAGCAA GTGCTGCAGC 
AAGCCACAGG TGGACATGCG GAAGCACGTG GCCATGACCC TGCTGGACAC AGAGCAGTCG 
TATGTGGAGT CGCTGCGCAC CCTGATGCAG GGCTACATGC AGCCGCTGAA GCAGCCAGAG 
AACTCCGTGC TCTGTGACCC TTCACTGGTG GACGAGATCT TCGACCAGAT CCCCGAGCTC 
CTGGAGCACC ACGAGCAATT CCTGGAGCAG GTTCGGCACT GCATGCAGAC CTGGCATGCC 
CAGCAGAAGG TGGGAGCCCT GCTCGTCCAG TCGTTCTCCA AGGATGTCCT AGTAAACATC 
TATTCTGCCT ATATCGATAA CTTCCTCAAT GCAAAGGATG CTGTGCGTGT GGCCAAGGAG 
GCGAGGCCTG CCTTTCTCAA GTTCCTAGAG CAAAGCATGC GTGAGAACAA GGAGAAGCAG 
GCGCTGTCTG ACCTCATGAT CAAGCCTGTG CAGCGGATCC CACGCTACGA GCTTCTGGTG 
AAGGACCTCC TGAAGCATAC ACCTGAGGAC CACCCGGACC ATCCACTCCT GCTGGAGGCG 
CAGCGGAACA TCAAGCAGGT GGCTGAGCGC ATCAACAAGG GTGTGCGGAG TGCCGAGGAG 
GCGGAGCGCC ATGCCCGTGT GCTGCAGGAG ATAGAGGCTC ACATCGAGGG CATGGAGGAT 
CTCCAGGCCC CTCTGCGGCG GTTCCTGAGA CAGGAGATGG TCATTGAAGT GAAGGCGATC 
GGTGGCAAGA AGGACCGGTC TCTCTTCCTG TTCACGGACC TCATCGTCTG CACCACTCTG 
AAGCGAAAGT CAGGCTCCCT GCGGCGCAGC TCCATGAGCC TGTACACGGC AGCCAGTGTC 
ATTGACACAG CCAGCAAGTA CAAGATGCTG TGGAAGCTGC CGCTGGAAGA CGCAGACATC 
ATCAAAGGGG CATCCCAAGC CACCAATCGG GAGAACATCC AGAAGGCCAT CAGCCGCCTT 
GATGAGGACC TCACCACCCT GGGCCAAATG AGCAAGCTCT CTGAGAGCCT TGGTTTCCCC 
CACCAGAGCC TGGACGATGC ACTGCGGGAC CTCTCAGCTG CCATGCACCG GGACCTGTCG 
GAGAAGCAGG CGCTGTGCTA CGCGCTTTCC TTCCCGCCAA CCAAGCTGGA GCTGTGCGCC 
ACTCGGCCCG AGGGCACCGA CTCCTACATT TTTGAGTTCC CTCACCCTGA CGCCCGCCTT 
GGTTTTGAAC AGGCCTTCGA TGAGGCCAAG AGGAAGCTGG CATCCAGCAA AAGCTGTCTA 
GACCCTGAGT TCCTGAAGGC CATCCCCATC ATGAAAACCC GCAGTGGCAT GCAGTTCTCC 
TGTGCGGCTC CCACCCTGAA CAGCTGCCCG GAGCCCTCGC CTGAGGTATG GGTCTGCAAC 
AGCGACGGCT ACGTGGGCCA GGTGTGCCTG CTGAGCCTGC GCGCCGAGCC GGACGTGGAG 
GCCTGCATCG CCGTCTGTTC CGCCCGCATC CTCTGCATCG GGGCGGTGCC CGGGCTGCAG 
CCTCGCTGCC ACCGGGAGCC TCCTCCGTCG CTGAGGAGTC CTCCAGAGAC GGCACCGGAG 
CCCGCCGGGC CGGAGCTGGA CGTCGAGGCC GCTGCAGACG AGGAAGCCGC GACGCTCGCG 
GAGCCGGGGC CGCAGCCCTG CCTTCACATC TCCATTGCAG GCTCGGGCTT GGAGATGACG 
CCGGGCCTCG GCGAGGGTGA CCCCCGCCCA GAGCTGGTGC CCTTTGACAG TGACTCTGAC 
GATGAGTCTT CGCCCAGCCC CTCGGGGACG CTGCAGAGCC AGGCCAGCCG GTCCACCATC 
TCCTCCAGCT TTGGCAATGA GGAGACCCCG AGTTCCAAGG AGGCCACGGC AGAGACCACC 
AGCTCAGAGG AGGAGCAGGA GCCAGGCTTC CTGCCACTGT CTGGCTCCTT TGGGCCTGGT 
GGTCCCTGCG GCACCAGCCC AATGGATGGG AGAGCCCTTC GCCGCTCCAG CCACGGCTCC 
TTCACCCGGG GCAGCCTTGA GGACCTGCTG AGTGTCGACC CTGAGGCCTA CCAGAGCTCC 
GTGTGGCTGG GCACTGAGGA TGGCTGTGTC CACGTGTACC AGTCCTCCGA CAGCATCCGT 
GACCGCAGGA ACAGCATGAA GCTCCAGCAT GCGGCCTCTG TGACCTGCAT CTTGTATCTG 
AATAACCAGG TGTTTGTGTC TCTGGCCAAT GGAGAGCTTG TGGTCTACCA AAGGGAAGCA 
GGCCATTTCT GGGACCCCCA GAACTTCAAA TCAGTGACCT TGGGCACCCA GGGGAGCCCC 
ATCACCAAGA TGGTATCTGT GGGTGGGCGG CTGTGGTGTG GCTGCCAGAA CCGAGTCCTT 
GTCCTGAGCC CTGACACGCT GCAGCTGGAG CACATGTTTT ACGTGGGTCA GGATTCAAGC 
CGCTGCGTGG CTTGCATGGT GGACTCCAGC CTGGGTGTGT GGGTGACATT GAAAGGTAGT 
GCCCACGTGT GTCTCTACCA TCCAGACACC TTTGAGCAGC TGGCAGAAGT AGACGTCACT 
CCTCCCGTGC ACAGGATGCT GGCAGGCTCG GATGCCATCA TCCGGCAGCA CAAGGCTGCC 
TGTCTGCGAA TCACAGCGCT GCTGGTGTGT GAGGAGCTGC TGTGGGTGGG CACCAGTGCT 
GGTGTCGTCC TCACCATGCC CACTTCGCCC GGTACTGTCA GCTGCCCACG GGCACCACTC 
AGTCCCACAG GCCTCGGCCA GGGACACACC GGCCACGTCC GCTTCTTGGC TGCAGTCCAG 
CTGCCAGATG GCTTCAACCT GCTCTGCCCA ACCCCACCAC CTCCCCCAGA CACAGGCCCC 
GAGAAGCTGC CATCACTGGA GCACCGGGAC TCCCCTTGGC ACCGAGGCCC CGCCCCTGCC 
AGGCCTAAAA TGCTGGTTAT CAGTGGAGGT GATGGCTATG AGGACTTCCG ACTCAGCAGT 
GGGGGCGGCA GCAGCAGTGA GACTGTGGGT CGAGACGACA GCACAAACCA CCTCCTCCTG 
TGGAGGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055601.2
CDS	22..6213
Translation	MADGAPRPQLYRSVSFKLLERWSGGPGLREEDTDTPGLRRRASCRPTTAARGQPSRRVSKLASGPLAAPAQPRPLRSLSPSVRQLSRRFDAPRLDDGSAGTRDGGVLPAAAEEAAEGPARGAWPSVTEMRKLFGGPGSRRPSADSESPGTPSPDGAAWEPPARESRQPPTPPPRTCFPLAGLRSARPLTGPETEGRLRRPQQQQERAQRPADGLHSWHIFSQPQAGARASCSSSSIAASYPVSRSRAASSSEEEEEGPPQLPGAQSPAYHGGHSSGSDDDRDGEGGHRWGGRPGLRPGSSLLDQDCRPDSDGLNLSSMNSAGVSGSPEPPTSPRAPREEGLREWGSGSPPCVPGPQEGLRPMSDSVGGAFRVAKVSFPSYLASPAGSRGSSRYSSTETLKDDDLWSSRGSGGWGVYRSPSFGAGEGLLRSQARTRAKGPGGTSRALRDGGFEPEKSRQRKSLSNPDIASETLTLLSFLRSDLSELRVRKPGGSSGDRGSNPLDGRDSPSAGGPVGQLEPIPIPAPASPGTRPTLKDLTATLRRAKSFTCSEKPMARRLPRTSALKSSSSELLLTGPGAEEDPLPLIVQDQYVQEARQVFEKIQRMGAQQDDGSDAPPGSPDWAGDVTRGQRSQEELSGPESSLTDEGIGADPEPPVAAFCGLGTTGMWRPLSSSSAQTNHHGPGTEDSLGGWALVSPETPPTPGALRRRRKVPPSGSGGSELSNGEAGEAYRSLSDPIPQRHRAATSEEPTGFSVDSNLLGSLSPKTGLPATSAMDEGLTSGHSDWSVGSEESKGYQEVIQSIVQGPGTLGRVVDDRIAGKAPKKKSLSDPSRRGELAGPGFEGPGGEPIREVEPMLPPSSSEPILVEQRAEPEEPGATRSRAQSERALPEALPPPATAHRNFHLDPKLADILSPRLIRRGSKKRPARSSHQELRRDEGSQDQTGSLSRARPSSRHVRHASVPATFMPIVVPEPPTSVGPPVAVPEPIGFPTRAHPTLQAPSLEDVTKQYMLNLHSGEVPAPVPVDMPCLPLAAPPSAEAKPPEAARPADEPTPASKCCSKPQVDMRKHVAMTLLDTEQSYVESLRTLMQGYMQPLKQPENSVLCDPSLVDEIFDQIPELLEHHEQFLEQVRHCMQTWHAQQKVGALLVQSFSKDVLVNIYSAYIDNFLNAKDAVRVAKEARPAFLKFLEQSMRENKEKQALSDLMIKPVQRIPRYELLVKDLLKHTPEDHPDHPLLLEAQRNIKQVAERINKGVRSAEEAERHARVLQEIEAHIEGMEDLQAPLRRFLRQEMVIEVKAIGGKKDRSLFLFTDLIVCTTLKRKSGSLRRSSMSLYTAASVIDTASKYKMLWKLPLEDADIIKGASQATNRENIQKAISRLDEDLTTLGQMSKLSESLGFPHQSLDDALRDLSAAMHRDLSEKQALCYALSFPPTKLELCATRPEGTDSYIFEFPHPDARLGFEQAFDEAKRKLASSKSCLDPEFLKAIPIMKTRSGMQFSCAAPTLNSCPEPSPEVWVCNSDGYVGQVCLLSLRAEPDVEACIAVCSARILCIGAVPGLQPRCHREPPPSLRSPPETAPEPAGPELDVEAAADEEAATLAEPGPQPCLHISIAGSGLEMTPGLGEGDPRPELVPFDSDSDDESSPSPSGTLQSQASRSTISSSFGNEETPSSKEATAETTSSEEEQEPGFLPLSGSFGPGGPCGTSPMDGRALRRSSHGSFTRGSLEDLLSVDPEAYQSSVWLGTEDGCVHVYQSSDSIRDRRNSMKLQHAASVTCILYLNNQVFVSLANGELVVYQREAGHFWDPQNFKSVTLGTQGSPITKMVSVGGRLWCGCQNRVLVLSPDTLQLEHMFYVGQDSSRCVACMVDSSLGVWVTLKGSAHVCLYHPDTFEQLAEVDVTPPVHRMLAGSDAIIRQHKAACLRITALLVCEELLWVGTSAGVVLTMPTSPGTVSCPRAPLSPTGLGQGHTGHVRFLAAVQLPDGFNLLCPTPPPPPDTGPEKLPSLEHRDSPWHRGPAPARPKMLVISGGDGYEDFRLSSGGGSSSETVGRDDSTNHLLLWRV

Target ORF information:

RefSeq Version	NM_014786.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rho guanine nucleotide exchange factor 17 (ARHGEF17), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014786.3

ORF Insert Sequence:

ATGGCGGACG GGGCACCCCG GCCCCAGCTT TACCGCAGCG TCTCGTTCAA GCTGCTGGAG 
CGCTGGAGCG GCGGCCCCGG GCTGAGGGAG GAGGACACGG ACACCCCCGG CTTGAGGCGA 
CGCGCCTCGT GCCGGCCGAC CACGGCTGCC CGGGGCCAGC CCTCTCGGCG CGTGTCCAAG 
CTGGCGTCTG GGCCCCTGGC CGCCCCCGCG CAGCCGCGCC CGCTCCGCAG CCTCTCGCCG 
TCGGTTCGCC AGCTCTCCCG GCGCTTCGAC GCGCCGCGTC TGGACGACGG CTCCGCTGGG 
ACCCGAGACG GAGGCGTCTT ACCCGCGGCC GCGGAAGAAG CGGCCGAGGG CCCAGCGCGA 
GGAGCCTGGC CCAGCGTCAC CGAGATGCGC AAGCTCTTCG GCGGTCCTGG CTCCAGGAGG 
CCCAGCGCCG ACTCTGAATC CCCAGGAACG CCCAGCCCCG ACGGTGCCGC GTGGGAGCCT 
CCGGCTCGGG AGTCGCGGCA GCCACCGACG CCACCCCCTC GGACATGCTT CCCCCTGGCG 
GGTCTGCGTT CGGCGCGGCC CCTGACCGGG CCGGAGACCG AAGGGAGGCT GCGCCGGCCG 
CAGCAGCAAC AGGAGCGGGC GCAGCGTCCA GCGGATGGTT TACATTCTTG GCATATCTTC 
TCCCAACCGC AGGCCGGGGC CCGGGCCTCC TGCTCCTCCT CCTCCATCGC CGCCTCCTAT 
CCTGTCAGCC GCAGTCGTGC TGCCAGCTCC AGCGAGGAGG AAGAGGAGGG CCCGCCGCAG 
CTGCCTGGAG CCCAGAGTCC GGCCTACCAC GGCGGCCACT CCTCGGGCAG TGACGACGAC 
CGAGACGGTG AGGGCGGCCA CCGCTGGGGA GGGAGGCCCG GGCTCAGGCC TGGAAGCTCC 
CTATTGGATC AGGACTGCAG GCCTGACAGT GATGGGTTAA ATCTAAGCAG CATGAACTCA 
GCAGGGGTTT CTGGGAGCCC TGAGCCCCCA ACATCTCCAA GAGCCCCTAG AGAAGAAGGA 
CTCCGGGAGT GGGGTAGTGG CTCTCCGCCC TGCGTCCCAG GTCCCCAGGA GGGACTTCGG 
CCTATGTCTG ACTCTGTGGG AGGAGCTTTC CGTGTGGCCA AGGTGAGCTT TCCCTCGTAC 
CTGGCCAGCC CCGCAGGCTC CCGCGGTAGC AGCCGTTATT CCAGCACGGA GACCCTCAAG 
GACGACGACC TATGGTCTAG TAGGGGTTCT GGGGGCTGGG GCGTGTACCG CTCCCCTAGC 
TTTGGAGCTG GGGAAGGGCT CCTGCGGTCC CAGGCTCGAA CCCGTGCCAA AGGACCTGGA 
GGCACCTCTA GGGCATTGAG GGATGGAGGA TTTGAGCCTG AAAAGAGTCG ACAGCGGAAG 
TCCCTGTCAA ATCCAGATAT CGCCTCAGAG ACCCTGACGC TTCTCAGTTT CCTGCGCTCA 
GACCTTTCAG AGCTGAGGGT CCGAAAACCT GGTGGGAGCT CCGGGGACCG TGGAAGCAAC 
CCCCTAGATG GCAGAGACTC ACCATCCGCA GGTGGCCCTG TGGGGCAACT TGAACCCATA 
CCCATCCCAG CCCCAGCATC ACCTGGCACG CGCCCCACAC TCAAGGACTT GACAGCCACT 
CTGCGGAGAG CAAAGTCATT CACCTGCTCT GAGAAGCCCA TGGCCCGCCG CCTGCCCCGC 
ACCAGTGCTC TGAAGTCCAG CTCCTCCGAG CTCCTGCTCA CAGGCCCTGG TGCCGAGGAG 
GATCCGCTGC CCCTCATCGT CCAGGACCAA TATGTGCAGG AGGCCCGCCA GGTTTTTGAG 
AAGATCCAGC GCATGGGTGC CCAACAAGAT GATGGAAGCG ATGCCCCCCC TGGAAGCCCT 
GACTGGGCAG GGGATGTGAC CCGAGGGCAG CGGTCCCAGG AGGAGCTCTC AGGCCCTGAG 
TCCAGTCTGA CAGATGAAGG CATTGGGGCA GACCCTGAGC CTCCTGTTGC AGCATTTTGC 
GGCCTGGGTA CCACAGGGAT GTGGCGACCT CTTTCCTCAT CCTCGGCCCA GACGAACCAC 
CATGGCCCTG GGACTGAGGA CAGTCTGGGC GGGTGGGCCC TGGTGTCGCC TGAGACCCCT 
CCCACACCAG GTGCCCTCCG CCGACGACGC AAAGTCCCAC CTTCAGGTTC TGGTGGGAGC 
GAATTGAGCA ATGGGGAGGC AGGGGAGGCC TACAGGTCCC TGAGTGACCC AATTCCTCAG 
CGCCACCGGG CTGCCACCTC TGAAGAGCCT ACTGGGTTCT CTGTGGACAG CAACCTCCTG 
GGCTCACTGA GCCCCAAGAC AGGGCTCCCT GCCACCTCAG CCATGGATGA GGGCTTGACC 
AGTGGTCACA GTGACTGGTC TGTGGGCAGT GAAGAGAGCA AGGGATATCA GGAGGTTATT 
CAGAGCATAG TTCAGGGGCC TGGCACCCTG GGGCGTGTGG TGGACGACAG GATTGCTGGC 
AAAGCCCCCA AGAAGAAATC CCTGAGTGAC CCCAGCCGCC GTGGGGAGCT GGCTGGGCCT 
GGATTCGAGG GCCCTGGAGG GGAGCCCATC CGAGAAGTTG AGCCCATGCT GCCTCCATCC 
AGCAGCGAGC CCATCCTTGT AGAGCAGCGG GCAGAGCCAG AAGAACCTGG TGCCACCAGG 
AGCCGGGCAC AGTCTGAAAG GGCCCTACCT GAGGCTCTGC CTCCCCCTGC CACTGCCCAC 
CGAAACTTTC ACCTTGACCC CAAGCTGGCT GACATTCTGT CCCCGAGGCT AATCCGCCGA 
GGCTCCAAGA AGCGCCCAGC TCGGAGTAGT CACCAGGAGC TTCGGAGAGA CGAGGGCAGT 
CAGGACCAGA CTGGCAGCCT GTCTCGGGCC CGGCCCTCCT CCAGACACGT TCGCCATGCC 
AGTGTGCCCG CCACATTTAT GCCTATTGTG GTGCCTGAGC CACCAACTTC TGTTGGTCCC 
CCTGTGGCTG TGCCAGAACC CATAGGCTTC CCTACCCGAG CCCATCCCAC GTTGCAGGCA 
CCATCGCTCG AGGACGTCAC CAAGCAGTAC ATGCTGAACC TGCACTCCGG TGAGGTCCCT 
GCCCCAGTGC CAGTGGACAT GCCCTGCTTG CCTCTGGCTG CACCGCCCTC TGCTGAGGCC 
AAGCCCCCTG AGGCAGCTCG GCCTGCAGAT GAGCCTACCC CTGCCAGCAA GTGCTGCAGC 
AAGCCACAGG TGGACATGCG GAAGCACGTG GCCATGACCC TGCTGGACAC AGAGCAGTCG 
TATGTGGAGT CGCTGCGCAC CCTGATGCAG GGCTACATGC AGCCGCTGAA GCAGCCAGAG 
AACTCCGTGC TCTGTGACCC TTCACTGGTG GACGAGATCT TCGACCAGAT CCCCGAGCTC 
CTGGAGCACC ACGAGCAATT CCTGGAGCAG GTTCGGCACT GCATGCAGAC CTGGCATGCC 
CAGCAGAAGG TGGGAGCCCT GCTCGTCCAG TCGTTCTCCA AGGATGTCCT AGTAAACATC 
TATTCTGCCT ATATCGATAA CTTCCTCAAT GCAAAGGATG CTGTGCGTGT GGCCAAGGAG 
GCGAGGCCTG CCTTTCTCAA GTTCCTAGAG CAAAGCATGC GTGAGAACAA GGAGAAGCAG 
GCGCTGTCTG ACCTCATGAT CAAGCCTGTG CAGCGGATCC CACGCTACGA GCTTCTGGTG 
AAGGACCTCC TGAAGCATAC ACCTGAGGAC CACCCGGACC ATCCACTCCT GCTGGAGGCG 
CAGCGGAACA TCAAGCAGGT GGCTGAGCGC ATCAACAAGG GTGTGCGGAG TGCCGAGGAG 
GCGGAGCGCC ATGCCCGTGT GCTGCAGGAG ATAGAGGCTC ACATCGAGGG CATGGAGGAT 
CTCCAGGCCC CTCTGCGGCG GTTCCTGAGA CAGGAGATGG TCATTGAAGT GAAGGCGATC 
GGTGGCAAGA AGGACCGGTC TCTCTTCCTG TTCACGGACC TCATCGTCTG CACCACTCTG 
AAGCGAAAGT CAGGCTCCCT GCGGCGCAGC TCCATGAGCC TGTACACGGC AGCCAGTGTC 
ATTGACACAG CCAGCAAGTA CAAGATGCTG TGGAAGCTGC CGCTGGAAGA CGCAGACATC 
ATCAAAGGGG CATCCCAAGC CACCAATCGG GAGAACATCC AGAAGGCCAT CAGCCGCCTT 
GATGAGGACC TCACCACCCT GGGCCAAATG AGCAAGCTCT CTGAGAGCCT TGGTTTCCCC 
CACCAGAGCC TGGACGATGC ACTGCGGGAC CTCTCAGCTG CCATGCACCG GGACCTGTCG 
GAGAAGCAGG CGCTGTGCTA CGCGCTTTCC TTCCCGCCAA CCAAGCTGGA GCTGTGCGCC 
ACTCGGCCCG AGGGCACCGA CTCCTACATT TTTGAGTTCC CTCACCCTGA CGCCCGCCTT 
GGTTTTGAAC AGGCCTTCGA TGAGGCCAAG AGGAAGCTGG CATCCAGCAA AAGCTGTCTA 
GACCCTGAGT TCCTGAAGGC CATCCCCATC ATGAAAACCC GCAGTGGCAT GCAGTTCTCC 
TGTGCGGCTC CCACCCTGAA CAGCTGCCCG GAGCCCTCGC CTGAGGTATG GGTCTGCAAC 
AGCGACGGCT ACGTGGGCCA GGTGTGCCTG CTGAGCCTGC GCGCCGAGCC GGACGTGGAG 
GCCTGCATCG CCGTCTGTTC CGCCCGCATC CTCTGCATCG GGGCGGTGCC CGGGCTGCAG 
CCTCGCTGCC ACCGGGAGCC TCCTCCGTCG CTGAGGAGTC CTCCAGAGAC GGCACCGGAG 
CCCGCCGGGC CGGAGCTGGA CGTCGAGGCC GCTGCAGACG AGGAAGCCGC GACGCTCGCG 
GAGCCGGGGC CGCAGCCCTG CCTTCACATC TCCATTGCAG GCTCGGGCTT GGAGATGACG 
CCGGGCCTCG GCGAGGGTGA CCCCCGCCCA GAGCTGGTGC CCTTTGACAG TGACTCTGAC 
GATGAGTCTT CGCCCAGCCC CTCGGGGACG CTGCAGAGCC AGGCCAGCCG GTCCACCATC 
TCCTCCAGCT TTGGCAATGA GGAGACCCCG AGTTCCAAGG AGGCCACGGC AGAGACCACC 
AGCTCAGAGG AGGAGCAGGA GCCAGGCTTC CTGCCACTGT CTGGCTCCTT TGGGCCTGGT 
GGTCCCTGCG GCACCAGCCC AATGGATGGG AGAGCCCTTC GCCGCTCCAG CCACGGCTCC 
TTCACCCGGG GCAGCCTTGA GGACCTGCTG AGTGTCGACC CTGAGGCCTA CCAGAGCTCC 
GTGTGGCTGG GCACTGAGGA TGGCTGTGTC CACGTGTACC AGTCCTCCGA CAGCATCCGT 
GACCGCAGGA ACAGCATGAA GCTCCAGCAT GCGGCCTCTG TGACCTGCAT CTTGTATCTG 
AATAACCAGG TGTTTGTGTC TCTGGCCAAT GGAGAGCTTG TGGTCTACCA AAGGGAAGCA 
GGCCATTTCT GGGACCCCCA GAACTTCAAA TCAGTGACCT TGGGCACCCA GGGGAGCCCC 
ATCACCAAGA TGGTATCTGT GGGTGGGCGG CTGTGGTGTG GCTGCCAGAA CCGAGTCCTT 
GTCCTGAGCC CTGACACGCT GCAGCTGGAG CACATGTTTT ACGTGGGTCA GGATTCAAGC 
CGCTGCGTGG CTTGCATGGT GGACTCCAGC CTGGGTGTGT GGGTGACATT GAAAGGTAGT 
GCCCACGTGT GTCTCTACCA TCCAGACACC TTTGAGCAGC TGGCAGAAGT AGACGTCACT 
CCTCCCGTGC ACAGGATGCT GGCAGGCTCG GATGCCATCA TCCGGCAGCA CAAGGCTGCC 
TGTCTGCGAA TCACAGCGCT GCTGGTGTGT GAGGAGCTGC TGTGGGTGGG CACCAGTGCT 
GGTGTCGTCC TCACCATGCC CACTTCGCCC GGTACTGTCA GCTGCCCACG GGCACCACTC 
AGTCCCACAG GCCTCGGCCA GGGACACACC GGCCACGTCC GCTTCTTGGC TGCAGTCCAG 
CTGCCAGATG GCTTCAACCT GCTCTGCCCA ACCCCACCAC CTCCCCCAGA CACAGGCCCC 
GAGAAGCTGC CATCACTGGA GCACCGGGAC TCCCCTTGGC ACCGAGGCCC CGCCCCTGCC 
AGGCCTAAAA TGCTGGTTAT CAGTGGAGGT GATGGCTATG AGGACTTCCG ACTCAGCAGT 
GGGGGCGGCA GCAGCAGTGA GACTGTGGGT CGAGACGACA GCACAAACCA CCTCCTCCTG 
TGGAGGGTGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ARHGEF17 is an essential spindle assembly checkpoint factor that targets Mps1 to kinetochores.
The Journal of cell biology212(6)647-59(2016 Mar)
Isokane M,Walter T,Mahen R,Nijmeijer B,H?rich? JK,Miura K,Maffini S,Ivanov MP,Kitajima TS,Peters JM,Ellenberg J

RhoGEF17, a Rho-specific guanine nucleotide exchange factor activated by phosphorylation via cyclic GMP-dependent kinase I?.
Cellular signalling25(3)630-8(2013 Mar)
Lutz S,Mohl M,Rauch J,Weber P,Wieland T

The RhoGEF TEM4 Regulates Endothelial Cell Migration by Suppressing Actomyosin Contractility.
PloS one8(6)e66260(2013)
Mitin N,Rossman KL,Currin R,Anne S,Marshall TW,Bear JE,Bautch VL,Der CJ

Genome-wide joint meta-analysis of SNP and SNP-by-smoking interaction identifies novel loci for pulmonary function.
PLoS genetics8(12)e1003098(2012)
Hancock DB,Soler Artigas M,Gharib SA,Henry A,Manichaikul A,Ramasamy A,Loth DW,Imboden M,Koch B,McArdle WL,Smith AV,Smolonska J,Sood A,Tang W,Wilk JB,Zhai G,Zhao JH,Aschard H,Burkart KM,Curjuric I,Eijgelsheim M,Elliott P,Gu X,Harris TB,Janson C,Homuth G,Hysi PG,Liu JZ,Loehr LR,Lohman K,Loos RJ,Manning AK,Marciante KD,Obeidat M,Postma DS,Aldrich MC,Brusselle GG,Chen TH,Eiriksdottir G,Franceschini N,Heinrich J,Rotter JI,Wijmenga C,Williams OD,Bentley AR,Hofman A,Laurie CC,Lumley T,Morrison AC,Joubert BR,Rivadeneira F,Couper DJ,Kritchevsky SB,Liu Y,Wjst M,Wain LV,Vonk JM,Uitterlinden AG,Rochat T,Rich SS,Psaty BM,O'Connor GT,North KE,Mirel DB,Meibohm B,Launer LJ,Khaw KT,Hartikainen AL,Hammond CJ,Gl?ser S,Marchini J,Kraft P,Wareham NJ,V?lzke H,Stricker BH,Spector TD,Probst-Hensch NM,Jarvis D,Jarvelin MR,Heckbert SR,Gudnason V,Boezen HM,Barr RG,Cassano PA,Strachan DP,Fornage M,Hall IP,Dupuis J,Tobin MD,London SJ

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ARHGEF17 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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