PIEZO1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PIEZO1
Entrez Gene ID	9780
Full Name	piezo type mechanosensitive ion channel component 1
Synonyms	DHS,FAM38A,LMPH3,Mib
General protein information	Preferred Names piezo type mechanosensitive ion channel component 1 Names piezo-type mechanosensitive ion channel component 1 family with sequence similarity 38, member A membrane protein induced by beta-amyloid treatment
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q24.3
Summary	The protein encoded by this gene is a mechanically-activated ion channel that links mechanical forces to biological signals. The encoded protein contains 36 transmembrane domains and functions as a homotetramer. Defects in this gene have been associated with dehydrated hereditary stomatocytosis. [provided by RefSeq, Jul 2015].
Disorder MIM:	611184
Disorder Html:	Dehydrated hereditary stomatocytosis with or without pseudohyperkalemia and/or perinatal edema, 194380 (3); Lymphedema, hereditary, III, 616843 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001142864.3	NP_001136336.2	piezo-type mechanosensitive ion channel component 1
NM_001142864.4	NP_001136336.2	piezo-type mechanosensitive ion channel component 1

Pathways from BioSystems

Homologies

	FAM38A	XP_001099984.2
Bos taurus (cattle)	PIEZO1	XP_002694905.2
Gallus gallus (chicken)	FAM38A	XP_414209.4
Homo sapiens (human)	PIEZO1	NP_001136336.2
Rattus norvegicus (Norway rat)	Piezo1	NP_001070668.2
Mus musculus (house mouse)	Piezo1	NP_001032375.1
Xenopus tropicalis (tropical clawed frog)	piezo1	XP_002933721.2
Danio rerio (zebrafish)	piezo1	XP_696355.4
Pan troglodytes (chimpanzee)	PIEZO1	XP_003952965.1
Canis lupus familiaris (dog)	PIEZO1	XP_005620632.1

Gene Ontology
Bibliography

Related articles in PubMed

Investigating the structural dynamics of the PIEZO1 channel activation and inactivation by coarse-grained modeling.
Zheng W, Sachs F
Proteins85(12)2198-2208(2017 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The structural dynamics of the PIEZO1 channel activation and inactivation by coarse-grained modeling has been reported.
Title: Investigating the structural dynamics of the PIEZO1 channel activation and inactivation by coarse-grained modeling.

Additional alterations in mutant PIEZO1 channel kinetics, differences in response to osmotic stress, and altered membrane protein trafficking, predicting variant alleles that worsen or ameliorate erythrocyte hydration.
Title: Novel mechanisms of PIEZO1 dysfunction in hereditary xerocytosis.

platelets and Meg-01 cells express the MS cation channel Piezo1, which may contribute to Ca(2+) entry and thrombus formation under arterial shear.
Title: Evidence for shear-mediated Ca

Because Piezo1 senses both mechanical crowding and stretch, it may act as a homeostatic sensor to control epithelial cell numbers, triggering extrusion and apoptosis in crowded regions and cell division in sparse regions.
Title: Mechanical stretch triggers rapid epithelial cell division through Piezo1.

data demonstrate that PIEZO1 is required for the regulation of NO formation, vascular tone, and blood pressure.
Title: Endothelial cation channel PIEZO1 controls blood pressure by mediating flow-induced ATP release.

The following PIEZO1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PIEZO1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu23112	NM_001142864.4 Latest version!	Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$929.50-$1301.30 $1859.00
View Old Accession Versions >>
OHu23112	NM_001142864.3	Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$929.50-$1301.30 $1859.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PIEZO1 ( NM_001142864.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136336.2 Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.

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CloneID	OHu23112
Clone ID Related Accession (Same CDS sequence)	NM_001142864.3 , NM_001142864.4
Accession Version	NM_001142864.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	piezo-type mechanosensitive ion channel component 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY165228.1, CN280966.1, DR731297.1, AC138028.1, DV080374.1, DV080349.1, AA682915.1, AB161230.1 and BU633404.1. This sequence is a reference standard in the RefSeqGene project. On Jul 10, 2015 this sequence version replaced NM_001142864.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCGC ACGTGCTCGG CGCGGTCCTG TACTGGCTGC TGCTGCCCTG CGCGCTGCTG 
GCTGCCTGCC TGCTCCGCTT CAGCGGACTC TCGCTGGTCT ACCTGCTCTT CCTGCTGCTG 
CTGCCCTGGT TCCCCGGCCC CACCCGATGC GGCCTCCAAG GTCACACAGG CCGCCTCCTG 
CGGGCATTGC TGGGCCTCAG CCTGCTCTTC CTGGTGGCCC ATCTCGCCCT CCAGATCTGC 
CTGCATATTG TGCCCCGCCT GGACCAGCTC CTGGGACCCA GCTGCAGCCG CTGGGAGACC 
CTCTCGCGAC ACATAGGGGT CACAAGGCTG GACCTGAAGG ACATCCCCAA CGCCATCCGG 
CTGGTGGCCC CTGACCTGGG CATCTTGGTG GTCTCCTCTG TCTGCCTCGG CATCTGCGGG 
CGCCTTGCAA GGAACACCCG GCAGAGCCCA CATCCACGGG AGCTGGATGA TGATGAGAGG 
GATGTGGATG CCAGCCCGAC GGCAGGGCTG CAGGAAGCAG CAACGCTGGC CCCTACACGG 
AGGTCACGGC TGGCCGCTCG TTTCCGAGTC ACGGCCCACT GGCTGCTGGT GGCGGCTGGG 
CGGGTCCTGG CCGTAACACT GCTTGCACTG GCAGGCATCG CCCACCCCTC GGCCCTCTCC 
AGTGTCTACC TGCTGCTCTT CCTGGCCCTC TGCACCTGGT GGGCCTGCCA CTTTCCCATC 
AGCACTCGGG GCTTCAGCAG ACTCTGCGTC GCGGTGGGGT GCTTCGGCGC CGGCCATCTC 
ATCTGCCTCT ACTGCTACCA GATGCCCTTG GCACAGGCTC TGCTCCCGCC TGCCGGCATC 
TGGGCTAGGG TGCTGGGTCT CAAGGACTTC GTGGGTCCCA CCAACTGCTC CAGCCCCCAC 
GCGCTGGTCC TCAACACCGG CCTGGACTGG CCTGTGTATG CCAGCCCCGG CGTCCTCCTG 
CTGCTGTGCT ACGCCACGGC CTCTCTGCGC AAGCTCCGCG CGTACCGCCC CTCCGGCCAG 
AGGAAGGAGG CGGCAAAGGG GTATGAGGCT CGGGAGCTGG AGCTAGCAGA GCTGGACCAG 
TGGCCCCAGG AACGGGAGTC TGACCAGCAC GTGGTGCCCA CAGCACCCGA CACCGAGGCT 
GATAACTGCA TCGTGCACGA GCTGACCGGC CAGAGCTCCG TCCTGCGGCG GCCTGTGCGG 
CCCAAGCGGG CTGAGCCCAG GGAGGCGTCT CCGCTCCACA GCCTGGGCCA CCTCATCATG 
GACCAGAGCT ATGTGTGCGC GCTCATTGCC ATGATGGTAT GGAGCATCAC CTACCACAGC 
TGGCTGACCT TCGTACTGCT GCTCTGGGCC TGCCTCATCT GGACGGTGCG CAGCCGCCAC 
CAACTGGCCA TGCTGTGCTC GCCCTGCATC CTGCTGTATG GGATGACGCT GTGCTGCCTA 
CGCTACGTGT GGGCCATGGA CCTGCGCCCT GAGCTGCCCA CCACCCTGGG CCCCGTCAGC 
CTGCGCCAGC TGGGGCTGGA GCACACCCGC TACCCCTGTC TGGACCTTGG TGCCATGTTG 
CTCTACACCC TGACCTTCTG GCTCCTGCTG CGCCAGTTTG TGAAAGAGAA GCTGCTGAAG 
TGGGCAGAGT CTCCAGCTGC GCTGACGGAG GTCACCGTGG CAGACACAGA GCCCACGCGG 
ACGCAGACGC TGTTGCAGAG CCTGGGGGAG CTGGTGAAGG GCGTGTACGC CAAGTACTGG 
ATCTATGTGT GTGCTGGCAT GTTCATCGTG GTCAGCTTCG CCGGCCGCCT CGTGGTCTAC 
AAGATTGTCT ACATGTTCCT CTTCCTGCTC TGCCTCACCC TCTTCCAGGT CTACTACAGC 
CTGTGGCGGA AGCTGCTCAA GGCCTTCTGG TGGCTCGTGG TGGCCTACAC CATGCTGGTC 
CTCATCGCCG TCTACACCTT CCAGTTCCAG GACTTCCCTG CCTACTGGCG CAACCTCACT 
GGCTTCACCG ACGAGCAGCT GGGGGACCTG GGCCTGGAGC AGTTCAGCGT GTCCGAGCTC 
TTCTCCAGCA TCCTGGTGCC CGGCTTCTTC CTCCTGGCCT GCATCCTGCA GCTGCACTAC 
TTCCACAGGC CCTTCATGCA GCTCACCGAC ATGGAGCACG TGTCCCTGCC TGGCACGCGC 
CTCCCGCGCT GGGCTCACAG GCAGGATGCA GTGAGTGGGA CCCCACTGCT GCGGGAGGAG 
CAGCAGGAGC ATCAGCAGCA GCAGCAGGAG GAGGAGGAGG AGGAGGAGGA CTCCAGGGAC 
GAGGGGCTGG GCGTGGCCAC TCCCCACCAG GCCACGCAGG TGCCTGAAGG GGCAGCCAAG 
TGGGGCCTGG TGGCTGAGCG GCTGCTGGAG CTGGCAGCCG GCTTCTCGGA CGTCCTCTCA 
CGCGTGCAGG TGTTCCTGCG GCGGCTGCTG GAGCTTCACG TTTTCAAGCT GGTGGCCCTG 
TACACCGTCT GGGTGGCCCT GAAGGAGGTG TCGGTGATGA ACCTGCTGCT GGTGGTGCTG 
TGGGCCTTCG CCCTGCCCTA CCCACGCTTC CGGCCCATGG CCTCCTGCCT GTCCACCGTG 
TGGACCTGCG TCATCATCGT GTGTAAGATG CTGTACCAGC TCAAGGTTGT CAACCCCCAG 
GAGTATTCCA GCAACTGCAC CGAGCCCTTC CCCAACAGCA CCAACTTGCT GCCCACGGAG 
ATCAGCCAGT CCCTGCTGTA CCGGGGGCCC GTGGACCCTG CCAACTGGTT TGGGGTGCGG 
AAAGGGTTCC CCAACCTGGG CTACATCCAG AACCACCTGC AAGTGCTGCT GCTGCTGGTA 
TTCGAGGCCA TCGTGTACCG GCGCCAGGAG CACTACCGCC GGCAGCACCA GCTGGCCCCG 
CTGCCTGCCC AGGCCGTGTT TGCCAGCGGC ACCCGCCAGC AGCTGGACCA GGATCTGCTC 
GGCTGCCTCA AGTACTTCAT CAACTTCTTC TTCTACAAAT TCGGGCTGGA GATCTGCTTC 
CTGATGGCCG TGAACGTGAT CGGGCAGCGC ATGAACTTTC TGGTGACCCT GCACGGTTGC 
TGGCTGGTGG CCATCCTCAC CCGCAGGCAC CGCCAGGCCA TTGCCCGCCT CTGGCCCAAC 
TACTGCCTCT TCCTGGCGCT GTTCCTGCTG TACCAGTACC TGCTGTGCCT GGGGATGCCC 
CCGGCCCTGT GCATTGATTA TCCCTGGCGC TGGAGCCGGG CCGTCCCCAT GAACTCCGCA 
CTCATCAAGT GGCTGTACCT GCCTGATTTC TTCCGGGCCC CCAACTCCAC CAACCTCATC 
AGCGACTTTC TCCTGCTGCT GTGCGCCTCC CAGCAGTGGC AGGTGTTCTC AGCTGAGCGC 
ACAGAGGAGT GGCAGCGCAT GGCTGGCGTC AACACCGACC GCCTGGAGCC GCTGCGGGGG 
GAGCCCAACC CCGTGCCCAA CTTTATCCAC TGCAGGTCCT ACCTTGACAT GCTGAAGGTG 
GCCGTCTTCC GATACCTGTT CTGGCTGGTG CTGGTGGTGG TGTTTGTCAC GGGGGCCACC 
CGCATCAGCA TCTTCGGGCT GGGCTACCTG CTGGCCTGCT TCTACCTGCT GCTCTTCGGC 
ACGGCCCTGC TGCAGAGGGA CACACGGGCC CGCCTCGTGC TGTGGGACTG CCTCATTCTG 
TACAACGTCA CCGTCATCAT CTCCAAGAAC ATGCTGTCGC TCCTGGCCTG CGTCTTCGTG 
GAGCAGATGC AGACCGGCTT CTGCTGGGTC ATCCAGCTCT TCAGCCTTGT ATGCACCGTC 
AAGGGCTACT ATGACCCCAA GGAGATGATG GACAGAGACC AGGACTGCCT GCTGCCTGTG 
GAGGAGGCTG GCATCATCTG GGACAGCGTC TGCTTCTTCT TCCTGCTGCT GCAGCGCCGC 
GTCTTCCTTA GCCATTACTA CCTGCACGTC AGGGCCGACC TCCAGGCCAC CGCCCTGCTA 
GCCTCCAGGG GCTTCGCCCT CTACAACGCT GCCAACCTCA AGAGCATTGA CTTTCACCGC 
AGGATAGAGG AGAAGTCCCT GGCCCAGCTG AAAAGACAGA TGGAGCGTAT CCGTGCCAAG 
CAGGAGAAGC ACAGGCAGGG CCGGGTGGAC CGCAGTCGCC CCCAGGACAC CCTGGGCCCC 
AAGGACCCCG GCCTGGAGCC AGGGCCCGAC AGTCCAGGGG GCTCCTCCCC GCCACGGAGG 
CAGTGGTGGC GGCCCTGGCT GGACCACGCC ACAGTCATCC ACTCCGGGGA CTACTTCCTG 
TTTGAGTCCG ACAGTGAGGA AGAGGAGGAG GCTGTTCCTG AAGACCCGAG GCCGTCGGCA 
CAGAGTGCCT TCCAGCTGGC GTACCAGGCA TGGGTGACCA ACGCCCAGGC GGTGCTGAGG 
CGGCGGCAGC AGGAGCAGGA GCAGGCAAGG CAGGAACAGG CAGGACAGCT ACCCACAGGA 
GGTGGTCCCA GCCAGGAGGT GGAGCCAGCA GAGGGCCCCG AGGAGGCAGC GGCAGGCCGG 
AGCCATGTGG TGCAGAGGGT GCTGAGCACG GCGCAGTTCC TGTGGATGCT GGGGCAGGCG 
CTAGTGGATG AGCTGACACG CTGGCTGCAG GAGTTCACCC GGCACCACGG CACCATGAGC 
GACGTGCTGC GGGCAGAGCG CTACCTCCTC ACACAGGAGC TCCTGCAGGG CGGCGAAGTG 
CACAGGGGCG TGCTGGATCA GCTGTACACA AGCCAGGCCG AGGCCACGCT GCCAGGCCCC 
ACCGAGGCCC CCAATGCCCC AAGCACCGTG TCCAGTGGGC TGGGCGCGGA GGAGCCACTC 
AGCAGCATGA CAGACGACAT GGGCAGCCCC CTGAGCACCG GCTACCACAC GCGCAGTGGC 
AGTGAGGAGG CAGTCACCGA CCCCGGGGAG CGTGAGGCTG GTGCCTCTCT GTACCAGGGA 
CTGATGCGGA CGGCCAGCGA GCTGCTCCTG GACAGGCGCC TGCGCATCCC AGAGCTGGAG 
GAGGCAGAGC TGTTTGCGGA GGGGCAGGGC CGGGCGCTGC GGCTGCTGCG GGCCGTGTAC 
CAGTGTGTGG CCGCCCACTC GGAGCTGCTC TGCTACTTCA TCATCATCCT CAACCACATG 
GTCACGGCCT CCGCCGGCTC GCTGGTGCTG CCCGTGCTCG TCTTCCTGTG GGCCATGCTG 
TCGATCCCGA GGCCCAGCAA GCGCTTCTGG ATGACGGCCA TCGTCTTCAC CGAGATCGCG 
GTGGTCGTCA AGTACCTGTT CCAGTTTGGG TTCTTCCCCT GGAACAGCCA CGTGGTGCTG 
CGGCGCTACG AGAACAAGCC CTACTTCCCG CCCCGCATCC TGGGCCTGGA GAAGACTGAC 
GGCTACATCA AGTACGACCT GGTGCAGCTC ATGGCCCTTT TCTTCCACCG CTCCCAGCTG 
CTGTGCTATG GCCTCTGGGA CCATGAGGAG GACTCACCAT CCAAGGAGCA TGACAAGAGC 
GGCGAGGAGG AGCAGGGAGC CGAGGAGGGG CCAGGGGTGC CTGCGGCCAC CACCGAAGAC 
CACATTCAGG TGGAAGCCAG GGTCGGACCC ACGGACGGGA CCCCAGAACC CCAAGTGGAG 
CTCAGGCCCC GTGATACGAG GCGCATCAGT CTACGTTTTA GAAGAAGGAA GAAGGAGGGC 
CCAGCACGGA AAGGAGCGGC AGCCATCGAA GCTGAGGACA GGGAGGAAGA AGAGGGGGAG 
GAAGAGAAAG AGGCCCCCAC GGGGAGAGAG AAGAGGCCAA GCCGCTCTGG AGGAAGAGTA 
AGGGCGGCCG GGCGGCGGCT GCAGGGCTTC TGCCTGTCCC TGGCCCAGGG CACATATCGG 
CCGCTACGGC GCTTCTTCCA CGACATCCTG CACACCAAGT ACCGCGCAGC CACCGACGTC 
TATGCCCTCA TGTTCCTGGC TGATGTTGTC GACTTCATCA TCATCATTTT TGGCTTCTGG 
GCCTTTGGGA AGCACTCGGC GGCCACAGAC ATCACGTCCT CCCTATCAGA CGACCAGGTA 
CCCGAGGCTT TCCTGGTCAT GCTGCTGATC CAGTTCAGTA CCATGGTGGT TGACCGCGCC 
CTCTACCTGC GCAAGACCGT GCTGGGCAAG CTGGCCTTCC AGGTGGCGCT GGTGCTGGCC 
ATCCACCTAT GGATGTTCTT CATCCTGCCC GCCGTCACTG AGAGGATGTT CAACCAGAAT 
GTGGTGGCCC AGCTCTGGTA CTTCGTGAAG TGCATCTACT TCGCCCTGTC CGCCTACCAG 
ATCCGCTGCG GCTACCCCAC CCGCATCCTC GGCAACTTCC TCACCAAGAA GTACAATCAT 
CTCAACCTCT TCCTCTTCCA GGGGTTCCGG CTGGTGCCGT TCCTGGTGGA GCTGCGGGCA 
GTGATGGACT GGGTGTGGAC GGACACCACG CTGTCCCTGT CCAGCTGGAT GTGTGTGGAG 
GACATCTATG CCAACATCTT CATCATCAAA TGCAGCCGAG AGACAGAGAA GAAATACCCG 
CAGCCCAAAG GGCAGAAGAA GAAGAAGATC GTCAAGTACG GCATGGGTGG CCTCATCATC 
CTCTTCCTCA TCGCCATCAT CTGGTTCCCA CTGCTCTTCA TGTCGCTGGT GCGCTCCGTG 
GTTGGGGTTG TCAACCAGCC CATCGATGTC ACCGTCACCC TGAAGCTGGG CGGCTATGAG 
CCGCTGTTCA CCATGAGCGC CCAGCAGCCG TCCATCATCC CCTTCACGGC CCAGGCCTAT 
GAGGAGCTGT CCCGGCAGTT TGACCCCCAG CCGCTGGCCA TGCAGTTCAT CAGCCAGTAC 
AGCCCTGAGG ACATCGTCAC GGCGCAGATT GAGGGCAGCT CCGGGGCGCT GTGGCGCATC 
AGTCCCCCCA GCCGTGCCCA GATGAAGCGG GAGCTCTACA ACGGCACGGC CGACATCACC 
CTGCGCTTCA CCTGGAACTT CCAGAGGGAC CTGGCGAAGG GAGGCACTGT GGAGTATGCC 
AACGAGAAGC ACATGCTGGC CCTGGCCCCC AACAGCACTG CACGGCGGCA GCTGGCCAGC 
CTGCTCGAGG GCACCTCGGA CCAGTCTGTG GTCATCCCTA ATCTCTTCCC CAAGTACATC 
CGTGCCCCCA ACGGGCCCGA AGCCAACCCT GTGAAGCAGC TGCAGCCCAA TGAGGAGGCC 
GACTACCTCG GCGTGCGTAT CCAGCTGCGG AGGGAGCAGG GTGCGGGGGC CACCGGCTTC 
CTCGAATGGT GGGTCATCGA GCTGCAGGAG TGCCGGACCG ACTGCAACCT GCTGCCCATG 
GTCATTTTCA GTGACAAGGT CAGCCCACCG AGCCTCGGCT TCCTGGCTGG CTACGGCATC 
ATGGGGCTGT ACGTGTCCAT CGTGCTGGTC ATCGGCAAGT TCGTGCGCGG ATTCTTCAGC 
GAGATCTCGC ACTCCATTAT GTTCGAGGAG CTGCCGTGCG TGGACCGCAT CCTCAAGCTC 
TGCCAGGACA TCTTCCTGGT GCGGGAGACT CGGGAGCTGG AGCTGGAGGA GGAGTTGTAC 
GCCAAGCTCA TCTTCCTCTA CCGCTCACCG GAGACCATGA TCAAGTGGAC TCGTGAGAAG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136336.2
CDS	257..7822
Translation	MEPHVLGAVLYWLLLPCALLAACLLRFSGLSLVYLLFLLLLPWFPGPTRCGLQGHTGRLLRALLGLSLLFLVAHLALQICLHIVPRLDQLLGPSCSRWETLSRHIGVTRLDLKDIPNAIRLVAPDLGILVVSSVCLGICGRLARNTRQSPHPRELDDDERDVDASPTAGLQEAATLAPTRRSRLAARFRVTAHWLLVAAGRVLAVTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPISTRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGPTNCSSPHALVLNTGLDWPVYASPGVLLLLCYATASLRKLRAYRPSGQRKEAAKGYEARELELAELDQWPQERESDQHVVPTAPDTEADNCIVHELTGQSSVLRRPVRPKRAEPREASPLHSLGHLIMDQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCLRYVWAMDLRPELPTTLGPVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLKWAESPAALTEVTVADTEPTRTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTRLPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQATQVPEGAAKWGLVAERLLELAAGFSDVLSRVQVFLRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTEISQSLLYRGPVDPANWFGVRKGFPNLGYIQNHLQVLLLLVFEAIVYRRQEHYRRQHQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGCWLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRGEPNPVPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFSLVCTVKGYYDPKEMMDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDRSRPQDTLGPKDPGLEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEAVPEDPRPSAQSAFQLAYQAWVTNAQAVLRRRQQEQEQARQEQAGQLPTGGGPSQEVEPAEGPEEAAAGRSHVVQRVLSTAQFLWMLGQALVDELTRWLQEFTRHHGTMSDVLRAERYLLTQELLQGGEVHRGVLDQLYTSQAEATLPGPTEAPNAPSTVSSGLGAEEPLSSMTDDMGSPLSTGYHTRSGSEEAVTDPGEREAGASLYQGLMRTASELLLDRRLRIPELEEAELFAEGQGRALRLLRAVYQCVAAHSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIAVVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLLCYGLWDHEEDSPSKEHDKSGEEEQGAEEGPGVPAATTEDHIQVEARVGPTDGTPEPQVELRPRDTRRISLRFRRRKKEGPARKGAAAIEAEDREEEEGEEEKEAPTGREKRPSRSGGRVRAAGRRLQGFCLSLAQGTYRPLRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWAFGKHSAATDITSSLSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLAIHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASLLEGTSDQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGFLEWWVIELQECRTDCNLLPMVIFSDKVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE

Target ORF information:

RefSeq Version	NM_001142864.3
Organism	Homo sapiens(human)
Definition	Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142864.3

ORF Insert Sequence:

ATGGAGCCGC ACGTGCTCGG CGCGGTCCTG TACTGGCTGC TGCTGCCCTG CGCGCTGCTG 
GCTGCCTGCC TGCTCCGCTT CAGCGGACTC TCGCTGGTCT ACCTGCTCTT CCTGCTGCTG 
CTGCCCTGGT TCCCCGGCCC CACCCGATGC GGCCTCCAAG GTCACACAGG CCGCCTCCTG 
CGGGCATTGC TGGGCCTCAG CCTGCTCTTC CTGGTGGCCC ATCTCGCCCT CCAGATCTGC 
CTGCATATTG TGCCCCGCCT GGACCAGCTC CTGGGACCCA GCTGCAGCCG CTGGGAGACC 
CTCTCGCGAC ACATAGGGGT CACAAGGCTG GACCTGAAGG ACATCCCCAA CGCCATCCGG 
CTGGTGGCCC CTGACCTGGG CATCTTGGTG GTCTCCTCTG TCTGCCTCGG CATCTGCGGG 
CGCCTTGCAA GGAACACCCG GCAGAGCCCA CATCCACGGG AGCTGGATGA TGATGAGAGG 
GATGTGGATG CCAGCCCGAC GGCAGGGCTG CAGGAAGCAG CAACGCTGGC CCCTACACGG 
AGGTCACGGC TGGCCGCTCG TTTCCGAGTC ACGGCCCACT GGCTGCTGGT GGCGGCTGGG 
CGGGTCCTGG CCGTAACACT GCTTGCACTG GCAGGCATCG CCCACCCCTC GGCCCTCTCC 
AGTGTCTACC TGCTGCTCTT CCTGGCCCTC TGCACCTGGT GGGCCTGCCA CTTTCCCATC 
AGCACTCGGG GCTTCAGCAG ACTCTGCGTC GCGGTGGGGT GCTTCGGCGC CGGCCATCTC 
ATCTGCCTCT ACTGCTACCA GATGCCCTTG GCACAGGCTC TGCTCCCGCC TGCCGGCATC 
TGGGCTAGGG TGCTGGGTCT CAAGGACTTC GTGGGTCCCA CCAACTGCTC CAGCCCCCAC 
GCGCTGGTCC TCAACACCGG CCTGGACTGG CCTGTGTATG CCAGCCCCGG CGTCCTCCTG 
CTGCTGTGCT ACGCCACGGC CTCTCTGCGC AAGCTCCGCG CGTACCGCCC CTCCGGCCAG 
AGGAAGGAGG CGGCAAAGGG GTATGAGGCT CGGGAGCTGG AGCTAGCAGA GCTGGACCAG 
TGGCCCCAGG AACGGGAGTC TGACCAGCAC GTGGTGCCCA CAGCACCCGA CACCGAGGCT 
GATAACTGCA TCGTGCACGA GCTGACCGGC CAGAGCTCCG TCCTGCGGCG GCCTGTGCGG 
CCCAAGCGGG CTGAGCCCAG GGAGGCGTCT CCGCTCCACA GCCTGGGCCA CCTCATCATG 
GACCAGAGCT ATGTGTGCGC GCTCATTGCC ATGATGGTAT GGAGCATCAC CTACCACAGC 
TGGCTGACCT TCGTACTGCT GCTCTGGGCC TGCCTCATCT GGACGGTGCG CAGCCGCCAC 
CAACTGGCCA TGCTGTGCTC GCCCTGCATC CTGCTGTATG GGATGACGCT GTGCTGCCTA 
CGCTACGTGT GGGCCATGGA CCTGCGCCCT GAGCTGCCCA CCACCCTGGG CCCCGTCAGC 
CTGCGCCAGC TGGGGCTGGA GCACACCCGC TACCCCTGTC TGGACCTTGG TGCCATGTTG 
CTCTACACCC TGACCTTCTG GCTCCTGCTG CGCCAGTTTG TGAAAGAGAA GCTGCTGAAG 
TGGGCAGAGT CTCCAGCTGC GCTGACGGAG GTCACCGTGG CAGACACAGA GCCCACGCGG 
ACGCAGACGC TGTTGCAGAG CCTGGGGGAG CTGGTGAAGG GCGTGTACGC CAAGTACTGG 
ATCTATGTGT GTGCTGGCAT GTTCATCGTG GTCAGCTTCG CCGGCCGCCT CGTGGTCTAC 
AAGATTGTCT ACATGTTCCT CTTCCTGCTC TGCCTCACCC TCTTCCAGGT CTACTACAGC 
CTGTGGCGGA AGCTGCTCAA GGCCTTCTGG TGGCTCGTGG TGGCCTACAC CATGCTGGTC 
CTCATCGCCG TCTACACCTT CCAGTTCCAG GACTTCCCTG CCTACTGGCG CAACCTCACT 
GGCTTCACCG ACGAGCAGCT GGGGGACCTG GGCCTGGAGC AGTTCAGCGT GTCCGAGCTC 
TTCTCCAGCA TCCTGGTGCC CGGCTTCTTC CTCCTGGCCT GCATCCTGCA GCTGCACTAC 
TTCCACAGGC CCTTCATGCA GCTCACCGAC ATGGAGCACG TGTCCCTGCC TGGCACGCGC 
CTCCCGCGCT GGGCTCACAG GCAGGATGCA GTGAGTGGGA CCCCACTGCT GCGGGAGGAG 
CAGCAGGAGC ATCAGCAGCA GCAGCAGGAG GAGGAGGAGG AGGAGGAGGA CTCCAGGGAC 
GAGGGGCTGG GCGTGGCCAC TCCCCACCAG GCCACGCAGG TGCCTGAAGG GGCAGCCAAG 
TGGGGCCTGG TGGCTGAGCG GCTGCTGGAG CTGGCAGCCG GCTTCTCGGA CGTCCTCTCA 
CGCGTGCAGG TGTTCCTGCG GCGGCTGCTG GAGCTTCACG TTTTCAAGCT GGTGGCCCTG 
TACACCGTCT GGGTGGCCCT GAAGGAGGTG TCGGTGATGA ACCTGCTGCT GGTGGTGCTG 
TGGGCCTTCG CCCTGCCCTA CCCACGCTTC CGGCCCATGG CCTCCTGCCT GTCCACCGTG 
TGGACCTGCG TCATCATCGT GTGTAAGATG CTGTACCAGC TCAAGGTTGT CAACCCCCAG 
GAGTATTCCA GCAACTGCAC CGAGCCCTTC CCCAACAGCA CCAACTTGCT GCCCACGGAG 
ATCAGCCAGT CCCTGCTGTA CCGGGGGCCC GTGGACCCTG CCAACTGGTT TGGGGTGCGG 
AAAGGGTTCC CCAACCTGGG CTACATCCAG AACCACCTGC AAGTGCTGCT GCTGCTGGTA 
TTCGAGGCCA TCGTGTACCG GCGCCAGGAG CACTACCGCC GGCAGCACCA GCTGGCCCCG 
CTGCCTGCCC AGGCCGTGTT TGCCAGCGGC ACCCGCCAGC AGCTGGACCA GGATCTGCTC 
GGCTGCCTCA AGTACTTCAT CAACTTCTTC TTCTACAAAT TCGGGCTGGA GATCTGCTTC 
CTGATGGCCG TGAACGTGAT CGGGCAGCGC ATGAACTTTC TGGTGACCCT GCACGGTTGC 
TGGCTGGTGG CCATCCTCAC CCGCAGGCAC CGCCAGGCCA TTGCCCGCCT CTGGCCCAAC 
TACTGCCTCT TCCTGGCGCT GTTCCTGCTG TACCAGTACC TGCTGTGCCT GGGGATGCCC 
CCGGCCCTGT GCATTGATTA TCCCTGGCGC TGGAGCCGGG CCGTCCCCAT GAACTCCGCA 
CTCATCAAGT GGCTGTACCT GCCTGATTTC TTCCGGGCCC CCAACTCCAC CAACCTCATC 
AGCGACTTTC TCCTGCTGCT GTGCGCCTCC CAGCAGTGGC AGGTGTTCTC AGCTGAGCGC 
ACAGAGGAGT GGCAGCGCAT GGCTGGCGTC AACACCGACC GCCTGGAGCC GCTGCGGGGG 
GAGCCCAACC CCGTGCCCAA CTTTATCCAC TGCAGGTCCT ACCTTGACAT GCTGAAGGTG 
GCCGTCTTCC GATACCTGTT CTGGCTGGTG CTGGTGGTGG TGTTTGTCAC GGGGGCCACC 
CGCATCAGCA TCTTCGGGCT GGGCTACCTG CTGGCCTGCT TCTACCTGCT GCTCTTCGGC 
ACGGCCCTGC TGCAGAGGGA CACACGGGCC CGCCTCGTGC TGTGGGACTG CCTCATTCTG 
TACAACGTCA CCGTCATCAT CTCCAAGAAC ATGCTGTCGC TCCTGGCCTG CGTCTTCGTG 
GAGCAGATGC AGACCGGCTT CTGCTGGGTC ATCCAGCTCT TCAGCCTTGT ATGCACCGTC 
AAGGGCTACT ATGACCCCAA GGAGATGATG GACAGAGACC AGGACTGCCT GCTGCCTGTG 
GAGGAGGCTG GCATCATCTG GGACAGCGTC TGCTTCTTCT TCCTGCTGCT GCAGCGCCGC 
GTCTTCCTTA GCCATTACTA CCTGCACGTC AGGGCCGACC TCCAGGCCAC CGCCCTGCTA 
GCCTCCAGGG GCTTCGCCCT CTACAACGCT GCCAACCTCA AGAGCATTGA CTTTCACCGC 
AGGATAGAGG AGAAGTCCCT GGCCCAGCTG AAAAGACAGA TGGAGCGTAT CCGTGCCAAG 
CAGGAGAAGC ACAGGCAGGG CCGGGTGGAC CGCAGTCGCC CCCAGGACAC CCTGGGCCCC 
AAGGACCCCG GCCTGGAGCC AGGGCCCGAC AGTCCAGGGG GCTCCTCCCC GCCACGGAGG 
CAGTGGTGGC GGCCCTGGCT GGACCACGCC ACAGTCATCC ACTCCGGGGA CTACTTCCTG 
TTTGAGTCCG ACAGTGAGGA AGAGGAGGAG GCTGTTCCTG AAGACCCGAG GCCGTCGGCA 
CAGAGTGCCT TCCAGCTGGC GTACCAGGCA TGGGTGACCA ACGCCCAGGC GGTGCTGAGG 
CGGCGGCAGC AGGAGCAGGA GCAGGCAAGG CAGGAACAGG CAGGACAGCT ACCCACAGGA 
GGTGGTCCCA GCCAGGAGGT GGAGCCAGCA GAGGGCCCCG AGGAGGCAGC GGCAGGCCGG 
AGCCATGTGG TGCAGAGGGT GCTGAGCACG GCGCAGTTCC TGTGGATGCT GGGGCAGGCG 
CTAGTGGATG AGCTGACACG CTGGCTGCAG GAGTTCACCC GGCACCACGG CACCATGAGC 
GACGTGCTGC GGGCAGAGCG CTACCTCCTC ACACAGGAGC TCCTGCAGGG CGGCGAAGTG 
CACAGGGGCG TGCTGGATCA GCTGTACACA AGCCAGGCCG AGGCCACGCT GCCAGGCCCC 
ACCGAGGCCC CCAATGCCCC AAGCACCGTG TCCAGTGGGC TGGGCGCGGA GGAGCCACTC 
AGCAGCATGA CAGACGACAT GGGCAGCCCC CTGAGCACCG GCTACCACAC GCGCAGTGGC 
AGTGAGGAGG CAGTCACCGA CCCCGGGGAG CGTGAGGCTG GTGCCTCTCT GTACCAGGGA 
CTGATGCGGA CGGCCAGCGA GCTGCTCCTG GACAGGCGCC TGCGCATCCC AGAGCTGGAG 
GAGGCAGAGC TGTTTGCGGA GGGGCAGGGC CGGGCGCTGC GGCTGCTGCG GGCCGTGTAC 
CAGTGTGTGG CCGCCCACTC GGAGCTGCTC TGCTACTTCA TCATCATCCT CAACCACATG 
GTCACGGCCT CCGCCGGCTC GCTGGTGCTG CCCGTGCTCG TCTTCCTGTG GGCCATGCTG 
TCGATCCCGA GGCCCAGCAA GCGCTTCTGG ATGACGGCCA TCGTCTTCAC CGAGATCGCG 
GTGGTCGTCA AGTACCTGTT CCAGTTTGGG TTCTTCCCCT GGAACAGCCA CGTGGTGCTG 
CGGCGCTACG AGAACAAGCC CTACTTCCCG CCCCGCATCC TGGGCCTGGA GAAGACTGAC 
GGCTACATCA AGTACGACCT GGTGCAGCTC ATGGCCCTTT TCTTCCACCG CTCCCAGCTG 
CTGTGCTATG GCCTCTGGGA CCATGAGGAG GACTCACCAT CCAAGGAGCA TGACAAGAGC 
GGCGAGGAGG AGCAGGGAGC CGAGGAGGGG CCAGGGGTGC CTGCGGCCAC CACCGAAGAC 
CACATTCAGG TGGAAGCCAG GGTCGGACCC ACGGACGGGA CCCCAGAACC CCAAGTGGAG 
CTCAGGCCCC GTGATACGAG GCGCATCAGT CTACGTTTTA GAAGAAGGAA GAAGGAGGGC 
CCAGCACGGA AAGGAGCGGC AGCCATCGAA GCTGAGGACA GGGAGGAAGA AGAGGGGGAG 
GAAGAGAAAG AGGCCCCCAC GGGGAGAGAG AAGAGGCCAA GCCGCTCTGG AGGAAGAGTA 
AGGGCGGCCG GGCGGCGGCT GCAGGGCTTC TGCCTGTCCC TGGCCCAGGG CACATATCGG 
CCGCTACGGC GCTTCTTCCA CGACATCCTG CACACCAAGT ACCGCGCAGC CACCGACGTC 
TATGCCCTCA TGTTCCTGGC TGATGTTGTC GACTTCATCA TCATCATTTT TGGCTTCTGG 
GCCTTTGGGA AGCACTCGGC GGCCACAGAC ATCACGTCCT CCCTATCAGA CGACCAGGTA 
CCCGAGGCTT TCCTGGTCAT GCTGCTGATC CAGTTCAGTA CCATGGTGGT TGACCGCGCC 
CTCTACCTGC GCAAGACCGT GCTGGGCAAG CTGGCCTTCC AGGTGGCGCT GGTGCTGGCC 
ATCCACCTAT GGATGTTCTT CATCCTGCCC GCCGTCACTG AGAGGATGTT CAACCAGAAT 
GTGGTGGCCC AGCTCTGGTA CTTCGTGAAG TGCATCTACT TCGCCCTGTC CGCCTACCAG 
ATCCGCTGCG GCTACCCCAC CCGCATCCTC GGCAACTTCC TCACCAAGAA GTACAATCAT 
CTCAACCTCT TCCTCTTCCA GGGGTTCCGG CTGGTGCCGT TCCTGGTGGA GCTGCGGGCA 
GTGATGGACT GGGTGTGGAC GGACACCACG CTGTCCCTGT CCAGCTGGAT GTGTGTGGAG 
GACATCTATG CCAACATCTT CATCATCAAA TGCAGCCGAG AGACAGAGAA GAAATACCCG 
CAGCCCAAAG GGCAGAAGAA GAAGAAGATC GTCAAGTACG GCATGGGTGG CCTCATCATC 
CTCTTCCTCA TCGCCATCAT CTGGTTCCCA CTGCTCTTCA TGTCGCTGGT GCGCTCCGTG 
GTTGGGGTTG TCAACCAGCC CATCGATGTC ACCGTCACCC TGAAGCTGGG CGGCTATGAG 
CCGCTGTTCA CCATGAGCGC CCAGCAGCCG TCCATCATCC CCTTCACGGC CCAGGCCTAT 
GAGGAGCTGT CCCGGCAGTT TGACCCCCAG CCGCTGGCCA TGCAGTTCAT CAGCCAGTAC 
AGCCCTGAGG ACATCGTCAC GGCGCAGATT GAGGGCAGCT CCGGGGCGCT GTGGCGCATC 
AGTCCCCCCA GCCGTGCCCA GATGAAGCGG GAGCTCTACA ACGGCACGGC CGACATCACC 
CTGCGCTTCA CCTGGAACTT CCAGAGGGAC CTGGCGAAGG GAGGCACTGT GGAGTATGCC 
AACGAGAAGC ACATGCTGGC CCTGGCCCCC AACAGCACTG CACGGCGGCA GCTGGCCAGC 
CTGCTCGAGG GCACCTCGGA CCAGTCTGTG GTCATCCCTA ATCTCTTCCC CAAGTACATC 
CGTGCCCCCA ACGGGCCCGA AGCCAACCCT GTGAAGCAGC TGCAGCCCAA TGAGGAGGCC 
GACTACCTCG GCGTGCGTAT CCAGCTGCGG AGGGAGCAGG GTGCGGGGGC CACCGGCTTC 
CTCGAATGGT GGGTCATCGA GCTGCAGGAG TGCCGGACCG ACTGCAACCT GCTGCCCATG 
GTCATTTTCA GTGACAAGGT CAGCCCACCG AGCCTCGGCT TCCTGGCTGG CTACGGCATC 
ATGGGGCTGT ACGTGTCCAT CGTGCTGGTC ATCGGCAAGT TCGTGCGCGG ATTCTTCAGC 
GAGATCTCGC ACTCCATTAT GTTCGAGGAG CTGCCGTGCG TGGACCGCAT CCTCAAGCTC 
TGCCAGGACA TCTTCCTGGT GCGGGAGACT CGGGAGCTGG AGCTGGAGGA GGAGTTGTAC 
GCCAAGCTCA TCTTCCTCTA CCGCTCACCG GAGACCATGA TCAAGTGGAC TCGTGAGAAG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PIEZO1 ( NM_001142864.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001136336.2 Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.

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CloneID	OHu23112
Clone ID Related Accession (Same CDS sequence)	NM_001142864.3 , NM_001142864.4
Accession Version	NM_001142864.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 7566bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	piezo-type mechanosensitive ion channel component 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY165228.1, CN280966.1, DR731297.1, AC138028.1, DV080374.1, DV080349.1, AA682915.1, AB161230.1 and BU633404.1. This sequence is a reference standard in the RefSeqGene project. On May 11, 2018 this sequence version replaced NM_001142864.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301015.14/ ENSP00000301015.9 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCGC ACGTGCTCGG CGCGGTCCTG TACTGGCTGC TGCTGCCCTG CGCGCTGCTG 
GCTGCCTGCC TGCTCCGCTT CAGCGGACTC TCGCTGGTCT ACCTGCTCTT CCTGCTGCTG 
CTGCCCTGGT TCCCCGGCCC CACCCGATGC GGCCTCCAAG GTCACACAGG CCGCCTCCTG 
CGGGCATTGC TGGGCCTCAG CCTGCTCTTC CTGGTGGCCC ATCTCGCCCT CCAGATCTGC 
CTGCATATTG TGCCCCGCCT GGACCAGCTC CTGGGACCCA GCTGCAGCCG CTGGGAGACC 
CTCTCGCGAC ACATAGGGGT CACAAGGCTG GACCTGAAGG ACATCCCCAA CGCCATCCGG 
CTGGTGGCCC CTGACCTGGG CATCTTGGTG GTCTCCTCTG TCTGCCTCGG CATCTGCGGG 
CGCCTTGCAA GGAACACCCG GCAGAGCCCA CATCCACGGG AGCTGGATGA TGATGAGAGG 
GATGTGGATG CCAGCCCGAC GGCAGGGCTG CAGGAAGCAG CAACGCTGGC CCCTACACGG 
AGGTCACGGC TGGCCGCTCG TTTCCGAGTC ACGGCCCACT GGCTGCTGGT GGCGGCTGGG 
CGGGTCCTGG CCGTAACACT GCTTGCACTG GCAGGCATCG CCCACCCCTC GGCCCTCTCC 
AGTGTCTACC TGCTGCTCTT CCTGGCCCTC TGCACCTGGT GGGCCTGCCA CTTTCCCATC 
AGCACTCGGG GCTTCAGCAG ACTCTGCGTC GCGGTGGGGT GCTTCGGCGC CGGCCATCTC 
ATCTGCCTCT ACTGCTACCA GATGCCCTTG GCACAGGCTC TGCTCCCGCC TGCCGGCATC 
TGGGCTAGGG TGCTGGGTCT CAAGGACTTC GTGGGTCCCA CCAACTGCTC CAGCCCCCAC 
GCGCTGGTCC TCAACACCGG CCTGGACTGG CCTGTGTATG CCAGCCCCGG CGTCCTCCTG 
CTGCTGTGCT ACGCCACGGC CTCTCTGCGC AAGCTCCGCG CGTACCGCCC CTCCGGCCAG 
AGGAAGGAGG CGGCAAAGGG GTATGAGGCT CGGGAGCTGG AGCTAGCAGA GCTGGACCAG 
TGGCCCCAGG AACGGGAGTC TGACCAGCAC GTGGTGCCCA CAGCACCCGA CACCGAGGCT 
GATAACTGCA TCGTGCACGA GCTGACCGGC CAGAGCTCCG TCCTGCGGCG GCCTGTGCGG 
CCCAAGCGGG CTGAGCCCAG GGAGGCGTCT CCGCTCCACA GCCTGGGCCA CCTCATCATG 
GACCAGAGCT ATGTGTGCGC GCTCATTGCC ATGATGGTAT GGAGCATCAC CTACCACAGC 
TGGCTGACCT TCGTACTGCT GCTCTGGGCC TGCCTCATCT GGACGGTGCG CAGCCGCCAC 
CAACTGGCCA TGCTGTGCTC GCCCTGCATC CTGCTGTATG GGATGACGCT GTGCTGCCTA 
CGCTACGTGT GGGCCATGGA CCTGCGCCCT GAGCTGCCCA CCACCCTGGG CCCCGTCAGC 
CTGCGCCAGC TGGGGCTGGA GCACACCCGC TACCCCTGTC TGGACCTTGG TGCCATGTTG 
CTCTACACCC TGACCTTCTG GCTCCTGCTG CGCCAGTTTG TGAAAGAGAA GCTGCTGAAG 
TGGGCAGAGT CTCCAGCTGC GCTGACGGAG GTCACCGTGG CAGACACAGA GCCCACGCGG 
ACGCAGACGC TGTTGCAGAG CCTGGGGGAG CTGGTGAAGG GCGTGTACGC CAAGTACTGG 
ATCTATGTGT GTGCTGGCAT GTTCATCGTG GTCAGCTTCG CCGGCCGCCT CGTGGTCTAC 
AAGATTGTCT ACATGTTCCT CTTCCTGCTC TGCCTCACCC TCTTCCAGGT CTACTACAGC 
CTGTGGCGGA AGCTGCTCAA GGCCTTCTGG TGGCTCGTGG TGGCCTACAC CATGCTGGTC 
CTCATCGCCG TCTACACCTT CCAGTTCCAG GACTTCCCTG CCTACTGGCG CAACCTCACT 
GGCTTCACCG ACGAGCAGCT GGGGGACCTG GGCCTGGAGC AGTTCAGCGT GTCCGAGCTC 
TTCTCCAGCA TCCTGGTGCC CGGCTTCTTC CTCCTGGCCT GCATCCTGCA GCTGCACTAC 
TTCCACAGGC CCTTCATGCA GCTCACCGAC ATGGAGCACG TGTCCCTGCC TGGCACGCGC 
CTCCCGCGCT GGGCTCACAG GCAGGATGCA GTGAGTGGGA CCCCACTGCT GCGGGAGGAG 
CAGCAGGAGC ATCAGCAGCA GCAGCAGGAG GAGGAGGAGG AGGAGGAGGA CTCCAGGGAC 
GAGGGGCTGG GCGTGGCCAC TCCCCACCAG GCCACGCAGG TGCCTGAAGG GGCAGCCAAG 
TGGGGCCTGG TGGCTGAGCG GCTGCTGGAG CTGGCAGCCG GCTTCTCGGA CGTCCTCTCA 
CGCGTGCAGG TGTTCCTGCG GCGGCTGCTG GAGCTTCACG TTTTCAAGCT GGTGGCCCTG 
TACACCGTCT GGGTGGCCCT GAAGGAGGTG TCGGTGATGA ACCTGCTGCT GGTGGTGCTG 
TGGGCCTTCG CCCTGCCCTA CCCACGCTTC CGGCCCATGG CCTCCTGCCT GTCCACCGTG 
TGGACCTGCG TCATCATCGT GTGTAAGATG CTGTACCAGC TCAAGGTTGT CAACCCCCAG 
GAGTATTCCA GCAACTGCAC CGAGCCCTTC CCCAACAGCA CCAACTTGCT GCCCACGGAG 
ATCAGCCAGT CCCTGCTGTA CCGGGGGCCC GTGGACCCTG CCAACTGGTT TGGGGTGCGG 
AAAGGGTTCC CCAACCTGGG CTACATCCAG AACCACCTGC AAGTGCTGCT GCTGCTGGTA 
TTCGAGGCCA TCGTGTACCG GCGCCAGGAG CACTACCGCC GGCAGCACCA GCTGGCCCCG 
CTGCCTGCCC AGGCCGTGTT TGCCAGCGGC ACCCGCCAGC AGCTGGACCA GGATCTGCTC 
GGCTGCCTCA AGTACTTCAT CAACTTCTTC TTCTACAAAT TCGGGCTGGA GATCTGCTTC 
CTGATGGCCG TGAACGTGAT CGGGCAGCGC ATGAACTTTC TGGTGACCCT GCACGGTTGC 
TGGCTGGTGG CCATCCTCAC CCGCAGGCAC CGCCAGGCCA TTGCCCGCCT CTGGCCCAAC 
TACTGCCTCT TCCTGGCGCT GTTCCTGCTG TACCAGTACC TGCTGTGCCT GGGGATGCCC 
CCGGCCCTGT GCATTGATTA TCCCTGGCGC TGGAGCCGGG CCGTCCCCAT GAACTCCGCA 
CTCATCAAGT GGCTGTACCT GCCTGATTTC TTCCGGGCCC CCAACTCCAC CAACCTCATC 
AGCGACTTTC TCCTGCTGCT GTGCGCCTCC CAGCAGTGGC AGGTGTTCTC AGCTGAGCGC 
ACAGAGGAGT GGCAGCGCAT GGCTGGCGTC AACACCGACC GCCTGGAGCC GCTGCGGGGG 
GAGCCCAACC CCGTGCCCAA CTTTATCCAC TGCAGGTCCT ACCTTGACAT GCTGAAGGTG 
GCCGTCTTCC GATACCTGTT CTGGCTGGTG CTGGTGGTGG TGTTTGTCAC GGGGGCCACC 
CGCATCAGCA TCTTCGGGCT GGGCTACCTG CTGGCCTGCT TCTACCTGCT GCTCTTCGGC 
ACGGCCCTGC TGCAGAGGGA CACACGGGCC CGCCTCGTGC TGTGGGACTG CCTCATTCTG 
TACAACGTCA CCGTCATCAT CTCCAAGAAC ATGCTGTCGC TCCTGGCCTG CGTCTTCGTG 
GAGCAGATGC AGACCGGCTT CTGCTGGGTC ATCCAGCTCT TCAGCCTTGT ATGCACCGTC 
AAGGGCTACT ATGACCCCAA GGAGATGATG GACAGAGACC AGGACTGCCT GCTGCCTGTG 
GAGGAGGCTG GCATCATCTG GGACAGCGTC TGCTTCTTCT TCCTGCTGCT GCAGCGCCGC 
GTCTTCCTTA GCCATTACTA CCTGCACGTC AGGGCCGACC TCCAGGCCAC CGCCCTGCTA 
GCCTCCAGGG GCTTCGCCCT CTACAACGCT GCCAACCTCA AGAGCATTGA CTTTCACCGC 
AGGATAGAGG AGAAGTCCCT GGCCCAGCTG AAAAGACAGA TGGAGCGTAT CCGTGCCAAG 
CAGGAGAAGC ACAGGCAGGG CCGGGTGGAC CGCAGTCGCC CCCAGGACAC CCTGGGCCCC 
AAGGACCCCG GCCTGGAGCC AGGGCCCGAC AGTCCAGGGG GCTCCTCCCC GCCACGGAGG 
CAGTGGTGGC GGCCCTGGCT GGACCACGCC ACAGTCATCC ACTCCGGGGA CTACTTCCTG 
TTTGAGTCCG ACAGTGAGGA AGAGGAGGAG GCTGTTCCTG AAGACCCGAG GCCGTCGGCA 
CAGAGTGCCT TCCAGCTGGC GTACCAGGCA TGGGTGACCA ACGCCCAGGC GGTGCTGAGG 
CGGCGGCAGC AGGAGCAGGA GCAGGCAAGG CAGGAACAGG CAGGACAGCT ACCCACAGGA 
GGTGGTCCCA GCCAGGAGGT GGAGCCAGCA GAGGGCCCCG AGGAGGCAGC GGCAGGCCGG 
AGCCATGTGG TGCAGAGGGT GCTGAGCACG GCGCAGTTCC TGTGGATGCT GGGGCAGGCG 
CTAGTGGATG AGCTGACACG CTGGCTGCAG GAGTTCACCC GGCACCACGG CACCATGAGC 
GACGTGCTGC GGGCAGAGCG CTACCTCCTC ACACAGGAGC TCCTGCAGGG CGGCGAAGTG 
CACAGGGGCG TGCTGGATCA GCTGTACACA AGCCAGGCCG AGGCCACGCT GCCAGGCCCC 
ACCGAGGCCC CCAATGCCCC AAGCACCGTG TCCAGTGGGC TGGGCGCGGA GGAGCCACTC 
AGCAGCATGA CAGACGACAT GGGCAGCCCC CTGAGCACCG GCTACCACAC GCGCAGTGGC 
AGTGAGGAGG CAGTCACCGA CCCCGGGGAG CGTGAGGCTG GTGCCTCTCT GTACCAGGGA 
CTGATGCGGA CGGCCAGCGA GCTGCTCCTG GACAGGCGCC TGCGCATCCC AGAGCTGGAG 
GAGGCAGAGC TGTTTGCGGA GGGGCAGGGC CGGGCGCTGC GGCTGCTGCG GGCCGTGTAC 
CAGTGTGTGG CCGCCCACTC GGAGCTGCTC TGCTACTTCA TCATCATCCT CAACCACATG 
GTCACGGCCT CCGCCGGCTC GCTGGTGCTG CCCGTGCTCG TCTTCCTGTG GGCCATGCTG 
TCGATCCCGA GGCCCAGCAA GCGCTTCTGG ATGACGGCCA TCGTCTTCAC CGAGATCGCG 
GTGGTCGTCA AGTACCTGTT CCAGTTTGGG TTCTTCCCCT GGAACAGCCA CGTGGTGCTG 
CGGCGCTACG AGAACAAGCC CTACTTCCCG CCCCGCATCC TGGGCCTGGA GAAGACTGAC 
GGCTACATCA AGTACGACCT GGTGCAGCTC ATGGCCCTTT TCTTCCACCG CTCCCAGCTG 
CTGTGCTATG GCCTCTGGGA CCATGAGGAG GACTCACCAT CCAAGGAGCA TGACAAGAGC 
GGCGAGGAGG AGCAGGGAGC CGAGGAGGGG CCAGGGGTGC CTGCGGCCAC CACCGAAGAC 
CACATTCAGG TGGAAGCCAG GGTCGGACCC ACGGACGGGA CCCCAGAACC CCAAGTGGAG 
CTCAGGCCCC GTGATACGAG GCGCATCAGT CTACGTTTTA GAAGAAGGAA GAAGGAGGGC 
CCAGCACGGA AAGGAGCGGC AGCCATCGAA GCTGAGGACA GGGAGGAAGA AGAGGGGGAG 
GAAGAGAAAG AGGCCCCCAC GGGGAGAGAG AAGAGGCCAA GCCGCTCTGG AGGAAGAGTA 
AGGGCGGCCG GGCGGCGGCT GCAGGGCTTC TGCCTGTCCC TGGCCCAGGG CACATATCGG 
CCGCTACGGC GCTTCTTCCA CGACATCCTG CACACCAAGT ACCGCGCAGC CACCGACGTC 
TATGCCCTCA TGTTCCTGGC TGATGTTGTC GACTTCATCA TCATCATTTT TGGCTTCTGG 
GCCTTTGGGA AGCACTCGGC GGCCACAGAC ATCACGTCCT CCCTATCAGA CGACCAGGTA 
CCCGAGGCTT TCCTGGTCAT GCTGCTGATC CAGTTCAGTA CCATGGTGGT TGACCGCGCC 
CTCTACCTGC GCAAGACCGT GCTGGGCAAG CTGGCCTTCC AGGTGGCGCT GGTGCTGGCC 
ATCCACCTAT GGATGTTCTT CATCCTGCCC GCCGTCACTG AGAGGATGTT CAACCAGAAT 
GTGGTGGCCC AGCTCTGGTA CTTCGTGAAG TGCATCTACT TCGCCCTGTC CGCCTACCAG 
ATCCGCTGCG GCTACCCCAC CCGCATCCTC GGCAACTTCC TCACCAAGAA GTACAATCAT 
CTCAACCTCT TCCTCTTCCA GGGGTTCCGG CTGGTGCCGT TCCTGGTGGA GCTGCGGGCA 
GTGATGGACT GGGTGTGGAC GGACACCACG CTGTCCCTGT CCAGCTGGAT GTGTGTGGAG 
GACATCTATG CCAACATCTT CATCATCAAA TGCAGCCGAG AGACAGAGAA GAAATACCCG 
CAGCCCAAAG GGCAGAAGAA GAAGAAGATC GTCAAGTACG GCATGGGTGG CCTCATCATC 
CTCTTCCTCA TCGCCATCAT CTGGTTCCCA CTGCTCTTCA TGTCGCTGGT GCGCTCCGTG 
GTTGGGGTTG TCAACCAGCC CATCGATGTC ACCGTCACCC TGAAGCTGGG CGGCTATGAG 
CCGCTGTTCA CCATGAGCGC CCAGCAGCCG TCCATCATCC CCTTCACGGC CCAGGCCTAT 
GAGGAGCTGT CCCGGCAGTT TGACCCCCAG CCGCTGGCCA TGCAGTTCAT CAGCCAGTAC 
AGCCCTGAGG ACATCGTCAC GGCGCAGATT GAGGGCAGCT CCGGGGCGCT GTGGCGCATC 
AGTCCCCCCA GCCGTGCCCA GATGAAGCGG GAGCTCTACA ACGGCACGGC CGACATCACC 
CTGCGCTTCA CCTGGAACTT CCAGAGGGAC CTGGCGAAGG GAGGCACTGT GGAGTATGCC 
AACGAGAAGC ACATGCTGGC CCTGGCCCCC AACAGCACTG CACGGCGGCA GCTGGCCAGC 
CTGCTCGAGG GCACCTCGGA CCAGTCTGTG GTCATCCCTA ATCTCTTCCC CAAGTACATC 
CGTGCCCCCA ACGGGCCCGA AGCCAACCCT GTGAAGCAGC TGCAGCCCAA TGAGGAGGCC 
GACTACCTCG GCGTGCGTAT CCAGCTGCGG AGGGAGCAGG GTGCGGGGGC CACCGGCTTC 
CTCGAATGGT GGGTCATCGA GCTGCAGGAG TGCCGGACCG ACTGCAACCT GCTGCCCATG 
GTCATTTTCA GTGACAAGGT CAGCCCACCG AGCCTCGGCT TCCTGGCTGG CTACGGCATC 
ATGGGGCTGT ACGTGTCCAT CGTGCTGGTC ATCGGCAAGT TCGTGCGCGG ATTCTTCAGC 
GAGATCTCGC ACTCCATTAT GTTCGAGGAG CTGCCGTGCG TGGACCGCAT CCTCAAGCTC 
TGCCAGGACA TCTTCCTGGT GCGGGAGACT CGGGAGCTGG AGCTGGAGGA GGAGTTGTAC 
GCCAAGCTCA TCTTCCTCTA CCGCTCACCG GAGACCATGA TCAAGTGGAC TCGTGAGAAG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001136336.2
CDS	257..7822
Translation	MEPHVLGAVLYWLLLPCALLAACLLRFSGLSLVYLLFLLLLPWFPGPTRCGLQGHTGRLLRALLGLSLLFLVAHLALQICLHIVPRLDQLLGPSCSRWETLSRHIGVTRLDLKDIPNAIRLVAPDLGILVVSSVCLGICGRLARNTRQSPHPRELDDDERDVDASPTAGLQEAATLAPTRRSRLAARFRVTAHWLLVAAGRVLAVTLLALAGIAHPSALSSVYLLLFLALCTWWACHFPISTRGFSRLCVAVGCFGAGHLICLYCYQMPLAQALLPPAGIWARVLGLKDFVGPTNCSSPHALVLNTGLDWPVYASPGVLLLLCYATASLRKLRAYRPSGQRKEAAKGYEARELELAELDQWPQERESDQHVVPTAPDTEADNCIVHELTGQSSVLRRPVRPKRAEPREASPLHSLGHLIMDQSYVCALIAMMVWSITYHSWLTFVLLLWACLIWTVRSRHQLAMLCSPCILLYGMTLCCLRYVWAMDLRPELPTTLGPVSLRQLGLEHTRYPCLDLGAMLLYTLTFWLLLRQFVKEKLLKWAESPAALTEVTVADTEPTRTQTLLQSLGELVKGVYAKYWIYVCAGMFIVVSFAGRLVVYKIVYMFLFLLCLTLFQVYYSLWRKLLKAFWWLVVAYTMLVLIAVYTFQFQDFPAYWRNLTGFTDEQLGDLGLEQFSVSELFSSILVPGFFLLACILQLHYFHRPFMQLTDMEHVSLPGTRLPRWAHRQDAVSGTPLLREEQQEHQQQQQEEEEEEEDSRDEGLGVATPHQATQVPEGAAKWGLVAERLLELAAGFSDVLSRVQVFLRRLLELHVFKLVALYTVWVALKEVSVMNLLLVVLWAFALPYPRFRPMASCLSTVWTCVIIVCKMLYQLKVVNPQEYSSNCTEPFPNSTNLLPTEISQSLLYRGPVDPANWFGVRKGFPNLGYIQNHLQVLLLLVFEAIVYRRQEHYRRQHQLAPLPAQAVFASGTRQQLDQDLLGCLKYFINFFFYKFGLEICFLMAVNVIGQRMNFLVTLHGCWLVAILTRRHRQAIARLWPNYCLFLALFLLYQYLLCLGMPPALCIDYPWRWSRAVPMNSALIKWLYLPDFFRAPNSTNLISDFLLLLCASQQWQVFSAERTEEWQRMAGVNTDRLEPLRGEPNPVPNFIHCRSYLDMLKVAVFRYLFWLVLVVVFVTGATRISIFGLGYLLACFYLLLFGTALLQRDTRARLVLWDCLILYNVTVIISKNMLSLLACVFVEQMQTGFCWVIQLFSLVCTVKGYYDPKEMMDRDQDCLLPVEEAGIIWDSVCFFFLLLQRRVFLSHYYLHVRADLQATALLASRGFALYNAANLKSIDFHRRIEEKSLAQLKRQMERIRAKQEKHRQGRVDRSRPQDTLGPKDPGLEPGPDSPGGSSPPRRQWWRPWLDHATVIHSGDYFLFESDSEEEEEAVPEDPRPSAQSAFQLAYQAWVTNAQAVLRRRQQEQEQARQEQAGQLPTGGGPSQEVEPAEGPEEAAAGRSHVVQRVLSTAQFLWMLGQALVDELTRWLQEFTRHHGTMSDVLRAERYLLTQELLQGGEVHRGVLDQLYTSQAEATLPGPTEAPNAPSTVSSGLGAEEPLSSMTDDMGSPLSTGYHTRSGSEEAVTDPGEREAGASLYQGLMRTASELLLDRRLRIPELEEAELFAEGQGRALRLLRAVYQCVAAHSELLCYFIIILNHMVTASAGSLVLPVLVFLWAMLSIPRPSKRFWMTAIVFTEIAVVVKYLFQFGFFPWNSHVVLRRYENKPYFPPRILGLEKTDGYIKYDLVQLMALFFHRSQLLCYGLWDHEEDSPSKEHDKSGEEEQGAEEGPGVPAATTEDHIQVEARVGPTDGTPEPQVELRPRDTRRISLRFRRRKKEGPARKGAAAIEAEDREEEEGEEEKEAPTGREKRPSRSGGRVRAAGRRLQGFCLSLAQGTYRPLRRFFHDILHTKYRAATDVYALMFLADVVDFIIIIFGFWAFGKHSAATDITSSLSDDQVPEAFLVMLLIQFSTMVVDRALYLRKTVLGKLAFQVALVLAIHLWMFFILPAVTERMFNQNVVAQLWYFVKCIYFALSAYQIRCGYPTRILGNFLTKKYNHLNLFLFQGFRLVPFLVELRAVMDWVWTDTTLSLSSWMCVEDIYANIFIIKCSRETEKKYPQPKGQKKKKIVKYGMGGLIILFLIAIIWFPLLFMSLVRSVVGVVNQPIDVTVTLKLGGYEPLFTMSAQQPSIIPFTAQAYEELSRQFDPQPLAMQFISQYSPEDIVTAQIEGSSGALWRISPPSRAQMKRELYNGTADITLRFTWNFQRDLAKGGTVEYANEKHMLALAPNSTARRQLASLLEGTSDQSVVIPNLFPKYIRAPNGPEANPVKQLQPNEEADYLGVRIQLRREQGAGATGFLEWWVIELQECRTDCNLLPMVIFSDKVSPPSLGFLAGYGIMGLYVSIVLVIGKFVRGFFSEISHSIMFEELPCVDRILKLCQDIFLVRETRELELEEELYAKLIFLYRSPETMIKWTREKE

Target ORF information:

RefSeq Version	NM_001142864.4
Organism	Homo sapiens(human)
Definition	Homo sapiens piezo type mechanosensitive ion channel component 1 (PIEZO1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001142864.4

ORF Insert Sequence:

ATGGAGCCGC ACGTGCTCGG CGCGGTCCTG TACTGGCTGC TGCTGCCCTG CGCGCTGCTG 
GCTGCCTGCC TGCTCCGCTT CAGCGGACTC TCGCTGGTCT ACCTGCTCTT CCTGCTGCTG 
CTGCCCTGGT TCCCCGGCCC CACCCGATGC GGCCTCCAAG GTCACACAGG CCGCCTCCTG 
CGGGCATTGC TGGGCCTCAG CCTGCTCTTC CTGGTGGCCC ATCTCGCCCT CCAGATCTGC 
CTGCATATTG TGCCCCGCCT GGACCAGCTC CTGGGACCCA GCTGCAGCCG CTGGGAGACC 
CTCTCGCGAC ACATAGGGGT CACAAGGCTG GACCTGAAGG ACATCCCCAA CGCCATCCGG 
CTGGTGGCCC CTGACCTGGG CATCTTGGTG GTCTCCTCTG TCTGCCTCGG CATCTGCGGG 
CGCCTTGCAA GGAACACCCG GCAGAGCCCA CATCCACGGG AGCTGGATGA TGATGAGAGG 
GATGTGGATG CCAGCCCGAC GGCAGGGCTG CAGGAAGCAG CAACGCTGGC CCCTACACGG 
AGGTCACGGC TGGCCGCTCG TTTCCGAGTC ACGGCCCACT GGCTGCTGGT GGCGGCTGGG 
CGGGTCCTGG CCGTAACACT GCTTGCACTG GCAGGCATCG CCCACCCCTC GGCCCTCTCC 
AGTGTCTACC TGCTGCTCTT CCTGGCCCTC TGCACCTGGT GGGCCTGCCA CTTTCCCATC 
AGCACTCGGG GCTTCAGCAG ACTCTGCGTC GCGGTGGGGT GCTTCGGCGC CGGCCATCTC 
ATCTGCCTCT ACTGCTACCA GATGCCCTTG GCACAGGCTC TGCTCCCGCC TGCCGGCATC 
TGGGCTAGGG TGCTGGGTCT CAAGGACTTC GTGGGTCCCA CCAACTGCTC CAGCCCCCAC 
GCGCTGGTCC TCAACACCGG CCTGGACTGG CCTGTGTATG CCAGCCCCGG CGTCCTCCTG 
CTGCTGTGCT ACGCCACGGC CTCTCTGCGC AAGCTCCGCG CGTACCGCCC CTCCGGCCAG 
AGGAAGGAGG CGGCAAAGGG GTATGAGGCT CGGGAGCTGG AGCTAGCAGA GCTGGACCAG 
TGGCCCCAGG AACGGGAGTC TGACCAGCAC GTGGTGCCCA CAGCACCCGA CACCGAGGCT 
GATAACTGCA TCGTGCACGA GCTGACCGGC CAGAGCTCCG TCCTGCGGCG GCCTGTGCGG 
CCCAAGCGGG CTGAGCCCAG GGAGGCGTCT CCGCTCCACA GCCTGGGCCA CCTCATCATG 
GACCAGAGCT ATGTGTGCGC GCTCATTGCC ATGATGGTAT GGAGCATCAC CTACCACAGC 
TGGCTGACCT TCGTACTGCT GCTCTGGGCC TGCCTCATCT GGACGGTGCG CAGCCGCCAC 
CAACTGGCCA TGCTGTGCTC GCCCTGCATC CTGCTGTATG GGATGACGCT GTGCTGCCTA 
CGCTACGTGT GGGCCATGGA CCTGCGCCCT GAGCTGCCCA CCACCCTGGG CCCCGTCAGC 
CTGCGCCAGC TGGGGCTGGA GCACACCCGC TACCCCTGTC TGGACCTTGG TGCCATGTTG 
CTCTACACCC TGACCTTCTG GCTCCTGCTG CGCCAGTTTG TGAAAGAGAA GCTGCTGAAG 
TGGGCAGAGT CTCCAGCTGC GCTGACGGAG GTCACCGTGG CAGACACAGA GCCCACGCGG 
ACGCAGACGC TGTTGCAGAG CCTGGGGGAG CTGGTGAAGG GCGTGTACGC CAAGTACTGG 
ATCTATGTGT GTGCTGGCAT GTTCATCGTG GTCAGCTTCG CCGGCCGCCT CGTGGTCTAC 
AAGATTGTCT ACATGTTCCT CTTCCTGCTC TGCCTCACCC TCTTCCAGGT CTACTACAGC 
CTGTGGCGGA AGCTGCTCAA GGCCTTCTGG TGGCTCGTGG TGGCCTACAC CATGCTGGTC 
CTCATCGCCG TCTACACCTT CCAGTTCCAG GACTTCCCTG CCTACTGGCG CAACCTCACT 
GGCTTCACCG ACGAGCAGCT GGGGGACCTG GGCCTGGAGC AGTTCAGCGT GTCCGAGCTC 
TTCTCCAGCA TCCTGGTGCC CGGCTTCTTC CTCCTGGCCT GCATCCTGCA GCTGCACTAC 
TTCCACAGGC CCTTCATGCA GCTCACCGAC ATGGAGCACG TGTCCCTGCC TGGCACGCGC 
CTCCCGCGCT GGGCTCACAG GCAGGATGCA GTGAGTGGGA CCCCACTGCT GCGGGAGGAG 
CAGCAGGAGC ATCAGCAGCA GCAGCAGGAG GAGGAGGAGG AGGAGGAGGA CTCCAGGGAC 
GAGGGGCTGG GCGTGGCCAC TCCCCACCAG GCCACGCAGG TGCCTGAAGG GGCAGCCAAG 
TGGGGCCTGG TGGCTGAGCG GCTGCTGGAG CTGGCAGCCG GCTTCTCGGA CGTCCTCTCA 
CGCGTGCAGG TGTTCCTGCG GCGGCTGCTG GAGCTTCACG TTTTCAAGCT GGTGGCCCTG 
TACACCGTCT GGGTGGCCCT GAAGGAGGTG TCGGTGATGA ACCTGCTGCT GGTGGTGCTG 
TGGGCCTTCG CCCTGCCCTA CCCACGCTTC CGGCCCATGG CCTCCTGCCT GTCCACCGTG 
TGGACCTGCG TCATCATCGT GTGTAAGATG CTGTACCAGC TCAAGGTTGT CAACCCCCAG 
GAGTATTCCA GCAACTGCAC CGAGCCCTTC CCCAACAGCA CCAACTTGCT GCCCACGGAG 
ATCAGCCAGT CCCTGCTGTA CCGGGGGCCC GTGGACCCTG CCAACTGGTT TGGGGTGCGG 
AAAGGGTTCC CCAACCTGGG CTACATCCAG AACCACCTGC AAGTGCTGCT GCTGCTGGTA 
TTCGAGGCCA TCGTGTACCG GCGCCAGGAG CACTACCGCC GGCAGCACCA GCTGGCCCCG 
CTGCCTGCCC AGGCCGTGTT TGCCAGCGGC ACCCGCCAGC AGCTGGACCA GGATCTGCTC 
GGCTGCCTCA AGTACTTCAT CAACTTCTTC TTCTACAAAT TCGGGCTGGA GATCTGCTTC 
CTGATGGCCG TGAACGTGAT CGGGCAGCGC ATGAACTTTC TGGTGACCCT GCACGGTTGC 
TGGCTGGTGG CCATCCTCAC CCGCAGGCAC CGCCAGGCCA TTGCCCGCCT CTGGCCCAAC 
TACTGCCTCT TCCTGGCGCT GTTCCTGCTG TACCAGTACC TGCTGTGCCT GGGGATGCCC 
CCGGCCCTGT GCATTGATTA TCCCTGGCGC TGGAGCCGGG CCGTCCCCAT GAACTCCGCA 
CTCATCAAGT GGCTGTACCT GCCTGATTTC TTCCGGGCCC CCAACTCCAC CAACCTCATC 
AGCGACTTTC TCCTGCTGCT GTGCGCCTCC CAGCAGTGGC AGGTGTTCTC AGCTGAGCGC 
ACAGAGGAGT GGCAGCGCAT GGCTGGCGTC AACACCGACC GCCTGGAGCC GCTGCGGGGG 
GAGCCCAACC CCGTGCCCAA CTTTATCCAC TGCAGGTCCT ACCTTGACAT GCTGAAGGTG 
GCCGTCTTCC GATACCTGTT CTGGCTGGTG CTGGTGGTGG TGTTTGTCAC GGGGGCCACC 
CGCATCAGCA TCTTCGGGCT GGGCTACCTG CTGGCCTGCT TCTACCTGCT GCTCTTCGGC 
ACGGCCCTGC TGCAGAGGGA CACACGGGCC CGCCTCGTGC TGTGGGACTG CCTCATTCTG 
TACAACGTCA CCGTCATCAT CTCCAAGAAC ATGCTGTCGC TCCTGGCCTG CGTCTTCGTG 
GAGCAGATGC AGACCGGCTT CTGCTGGGTC ATCCAGCTCT TCAGCCTTGT ATGCACCGTC 
AAGGGCTACT ATGACCCCAA GGAGATGATG GACAGAGACC AGGACTGCCT GCTGCCTGTG 
GAGGAGGCTG GCATCATCTG GGACAGCGTC TGCTTCTTCT TCCTGCTGCT GCAGCGCCGC 
GTCTTCCTTA GCCATTACTA CCTGCACGTC AGGGCCGACC TCCAGGCCAC CGCCCTGCTA 
GCCTCCAGGG GCTTCGCCCT CTACAACGCT GCCAACCTCA AGAGCATTGA CTTTCACCGC 
AGGATAGAGG AGAAGTCCCT GGCCCAGCTG AAAAGACAGA TGGAGCGTAT CCGTGCCAAG 
CAGGAGAAGC ACAGGCAGGG CCGGGTGGAC CGCAGTCGCC CCCAGGACAC CCTGGGCCCC 
AAGGACCCCG GCCTGGAGCC AGGGCCCGAC AGTCCAGGGG GCTCCTCCCC GCCACGGAGG 
CAGTGGTGGC GGCCCTGGCT GGACCACGCC ACAGTCATCC ACTCCGGGGA CTACTTCCTG 
TTTGAGTCCG ACAGTGAGGA AGAGGAGGAG GCTGTTCCTG AAGACCCGAG GCCGTCGGCA 
CAGAGTGCCT TCCAGCTGGC GTACCAGGCA TGGGTGACCA ACGCCCAGGC GGTGCTGAGG 
CGGCGGCAGC AGGAGCAGGA GCAGGCAAGG CAGGAACAGG CAGGACAGCT ACCCACAGGA 
GGTGGTCCCA GCCAGGAGGT GGAGCCAGCA GAGGGCCCCG AGGAGGCAGC GGCAGGCCGG 
AGCCATGTGG TGCAGAGGGT GCTGAGCACG GCGCAGTTCC TGTGGATGCT GGGGCAGGCG 
CTAGTGGATG AGCTGACACG CTGGCTGCAG GAGTTCACCC GGCACCACGG CACCATGAGC 
GACGTGCTGC GGGCAGAGCG CTACCTCCTC ACACAGGAGC TCCTGCAGGG CGGCGAAGTG 
CACAGGGGCG TGCTGGATCA GCTGTACACA AGCCAGGCCG AGGCCACGCT GCCAGGCCCC 
ACCGAGGCCC CCAATGCCCC AAGCACCGTG TCCAGTGGGC TGGGCGCGGA GGAGCCACTC 
AGCAGCATGA CAGACGACAT GGGCAGCCCC CTGAGCACCG GCTACCACAC GCGCAGTGGC 
AGTGAGGAGG CAGTCACCGA CCCCGGGGAG CGTGAGGCTG GTGCCTCTCT GTACCAGGGA 
CTGATGCGGA CGGCCAGCGA GCTGCTCCTG GACAGGCGCC TGCGCATCCC AGAGCTGGAG 
GAGGCAGAGC TGTTTGCGGA GGGGCAGGGC CGGGCGCTGC GGCTGCTGCG GGCCGTGTAC 
CAGTGTGTGG CCGCCCACTC GGAGCTGCTC TGCTACTTCA TCATCATCCT CAACCACATG 
GTCACGGCCT CCGCCGGCTC GCTGGTGCTG CCCGTGCTCG TCTTCCTGTG GGCCATGCTG 
TCGATCCCGA GGCCCAGCAA GCGCTTCTGG ATGACGGCCA TCGTCTTCAC CGAGATCGCG 
GTGGTCGTCA AGTACCTGTT CCAGTTTGGG TTCTTCCCCT GGAACAGCCA CGTGGTGCTG 
CGGCGCTACG AGAACAAGCC CTACTTCCCG CCCCGCATCC TGGGCCTGGA GAAGACTGAC 
GGCTACATCA AGTACGACCT GGTGCAGCTC ATGGCCCTTT TCTTCCACCG CTCCCAGCTG 
CTGTGCTATG GCCTCTGGGA CCATGAGGAG GACTCACCAT CCAAGGAGCA TGACAAGAGC 
GGCGAGGAGG AGCAGGGAGC CGAGGAGGGG CCAGGGGTGC CTGCGGCCAC CACCGAAGAC 
CACATTCAGG TGGAAGCCAG GGTCGGACCC ACGGACGGGA CCCCAGAACC CCAAGTGGAG 
CTCAGGCCCC GTGATACGAG GCGCATCAGT CTACGTTTTA GAAGAAGGAA GAAGGAGGGC 
CCAGCACGGA AAGGAGCGGC AGCCATCGAA GCTGAGGACA GGGAGGAAGA AGAGGGGGAG 
GAAGAGAAAG AGGCCCCCAC GGGGAGAGAG AAGAGGCCAA GCCGCTCTGG AGGAAGAGTA 
AGGGCGGCCG GGCGGCGGCT GCAGGGCTTC TGCCTGTCCC TGGCCCAGGG CACATATCGG 
CCGCTACGGC GCTTCTTCCA CGACATCCTG CACACCAAGT ACCGCGCAGC CACCGACGTC 
TATGCCCTCA TGTTCCTGGC TGATGTTGTC GACTTCATCA TCATCATTTT TGGCTTCTGG 
GCCTTTGGGA AGCACTCGGC GGCCACAGAC ATCACGTCCT CCCTATCAGA CGACCAGGTA 
CCCGAGGCTT TCCTGGTCAT GCTGCTGATC CAGTTCAGTA CCATGGTGGT TGACCGCGCC 
CTCTACCTGC GCAAGACCGT GCTGGGCAAG CTGGCCTTCC AGGTGGCGCT GGTGCTGGCC 
ATCCACCTAT GGATGTTCTT CATCCTGCCC GCCGTCACTG AGAGGATGTT CAACCAGAAT 
GTGGTGGCCC AGCTCTGGTA CTTCGTGAAG TGCATCTACT TCGCCCTGTC CGCCTACCAG 
ATCCGCTGCG GCTACCCCAC CCGCATCCTC GGCAACTTCC TCACCAAGAA GTACAATCAT 
CTCAACCTCT TCCTCTTCCA GGGGTTCCGG CTGGTGCCGT TCCTGGTGGA GCTGCGGGCA 
GTGATGGACT GGGTGTGGAC GGACACCACG CTGTCCCTGT CCAGCTGGAT GTGTGTGGAG 
GACATCTATG CCAACATCTT CATCATCAAA TGCAGCCGAG AGACAGAGAA GAAATACCCG 
CAGCCCAAAG GGCAGAAGAA GAAGAAGATC GTCAAGTACG GCATGGGTGG CCTCATCATC 
CTCTTCCTCA TCGCCATCAT CTGGTTCCCA CTGCTCTTCA TGTCGCTGGT GCGCTCCGTG 
GTTGGGGTTG TCAACCAGCC CATCGATGTC ACCGTCACCC TGAAGCTGGG CGGCTATGAG 
CCGCTGTTCA CCATGAGCGC CCAGCAGCCG TCCATCATCC CCTTCACGGC CCAGGCCTAT 
GAGGAGCTGT CCCGGCAGTT TGACCCCCAG CCGCTGGCCA TGCAGTTCAT CAGCCAGTAC 
AGCCCTGAGG ACATCGTCAC GGCGCAGATT GAGGGCAGCT CCGGGGCGCT GTGGCGCATC 
AGTCCCCCCA GCCGTGCCCA GATGAAGCGG GAGCTCTACA ACGGCACGGC CGACATCACC 
CTGCGCTTCA CCTGGAACTT CCAGAGGGAC CTGGCGAAGG GAGGCACTGT GGAGTATGCC 
AACGAGAAGC ACATGCTGGC CCTGGCCCCC AACAGCACTG CACGGCGGCA GCTGGCCAGC 
CTGCTCGAGG GCACCTCGGA CCAGTCTGTG GTCATCCCTA ATCTCTTCCC CAAGTACATC 
CGTGCCCCCA ACGGGCCCGA AGCCAACCCT GTGAAGCAGC TGCAGCCCAA TGAGGAGGCC 
GACTACCTCG GCGTGCGTAT CCAGCTGCGG AGGGAGCAGG GTGCGGGGGC CACCGGCTTC 
CTCGAATGGT GGGTCATCGA GCTGCAGGAG TGCCGGACCG ACTGCAACCT GCTGCCCATG 
GTCATTTTCA GTGACAAGGT CAGCCCACCG AGCCTCGGCT TCCTGGCTGG CTACGGCATC 
ATGGGGCTGT ACGTGTCCAT CGTGCTGGTC ATCGGCAAGT TCGTGCGCGG ATTCTTCAGC 
GAGATCTCGC ACTCCATTAT GTTCGAGGAG CTGCCGTGCG TGGACCGCAT CCTCAAGCTC 
TGCCAGGACA TCTTCCTGGT GCGGGAGACT CGGGAGCTGG AGCTGGAGGA GGAGTTGTAC 
GCCAAGCTCA TCTTCCTCTA CCGCTCACCG GAGACCATGA TCAAGTGGAC TCGTGAGAAG 
GAGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Investigating the structural dynamics of the PIEZO1 channel activation and inactivation by coarse-grained modeling.
Proteins85(12)2198-2208(2017 Dec)
Zheng W,Sachs F

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PIEZO1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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