NOS1AP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NOS1AP
Entrez Gene ID	9722
Full Name	nitric oxide synthase 1 adaptor protein
Synonyms	6330408P19Rik,CAPON
General protein information	Preferred Names nitric oxide synthase 1 adaptor protein Names carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein C-terminal PDZ domain ligand of neuronal nitric oxide synthase (CAPON) C-terminal PDZ ligand of neuronal nitric oxide synthase protein ligand of neuronal nitric oxide synthase with carboxyl-terminal PDZ domain nitric oxide synthase 1 (neuronal) adaptor protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q23.3
Summary	This gene encodes a cytosolic protein that binds to the signaling molecule, neuronal nitric oxide synthase (nNOS). This protein has a C-terminal PDZ-binding domain that mediates interactions with nNOS and an N-terminal phosphotyrosine binding (PTB) domain that binds to the small monomeric G protein, Dexras1. Studies of the related mouse and rat proteins have shown that this protein functions as an adapter protein linking nNOS to specific targets, such as Dexras1 and the synapsins. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2009].
Disorder MIM:	605551

mRNA and Protein(s)

mRNA	Protein	Name
NM_001164757.1	NP_001158229.1	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 3
NM_001126060.1	NP_001119532.2	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 2
NM_014697.2	NP_055512.1	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1
NM_014697.3	NP_055512.1	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1
NM_001164757.2	NP_001158229.1	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	NOS1AP	NP_055512.1
Gallus gallus (chicken)	NOS1AP	XP_004943207.1
Bos taurus (cattle)	NOS1AP	NP_001139691.1
Pan troglodytes (chimpanzee)	LOC101058258	XP_003949677.1

Gene Ontology
Bibliography

Related articles in PubMed

The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population.
Hu G, Yang C, Zhao L, Fan Y, Lv Q, Zhao J, Zhu M, Guo X, Bao C, Xu A, Jie Y, Jiang Y, Zhang C, Yu S, Wang Z, Li Z, Yi Z
Progress in neuro-psychopharmacology & biological psychiatry81187-193(2018 Feb)

The genetic variation rs12143842 in NOS1AP increases idiopathic ventricular tachycardia risk in Chinese Han populations.
Zhang R, Chen F, Yu H, Gao L, Yin X, Dong Y, Yang Y, Xia Y
Scientific reports7(1)8356(2017 Aug)

Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis.
Winbo A, Stattin EL, Westin IM, Norberg A, Persson J, Jensen SM, Rydberg A
BMC medical genetics18(1)74(2017 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Association between NOS1AP and PTSD severity, depression, anxiety, and stress was found. NOS1AP was associated with resilience.
Title: Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience.

If the expression of Capon is decreased, myeloma cells are adhered to fibronectin or bone marrow stromal cells (bone marrow mesenchymal stem cells). In addition, the sensitivity of the cell line to chemotherapeutic agents was reduced after silencing Capon in the myeloma cell line which was adhered to bone marrow mesenchymal stem cells.
Title: The role of Capon in multiple myeloma.

sex was identified as a moderator of the association between NOS1AP sequence variants and QTc prolongation in two long QT syndrome founder populations
Title: Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis.

Results from genome-wide DNA methylation, functional network analysis and pyrosequencing, show selective CpG sites (NOS1AP, BID, and GABRB1) differentially methylated in smokers and chronic obstructive pulmonary disease patients compared to nonsmokers.
Title: DNA methylation profiling in peripheral lung tissues of smokers and patients with COPD.

Data indicate that overexpression of nitric oxide synthase 1 adaptor protein short form (CAPON-S) led to the inactivation of the proto-oncogene protein Akt (Akt) signaling pathway.
Title: Low Expression of CAPON in Glioma Contributes to Cell Proliferation via the Akt Signaling Pathway.

The following NOS1AP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NOS1AP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18983	NM_014697.3 Latest version!	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu09164	NM_001126060.1 Latest version!	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu10640	NM_001164757.2 Latest version!	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu18983	NM_014697.2	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu10640	NM_001164757.1	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NOS1AP ( NM_014697.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055512.1 Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18983
Clone ID Related Accession (Same CDS sequence)	NM_014697.2 , NM_014697.3
Accession Version	NM_014697.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB007933.2, BC112295.1 and AL512785.7. This sequence is a reference standard in the RefSeqGene project. On May 2, 2008 this sequence version replaced NM_014697.1. Transcript Variant: This variant (1) encodes the full-length protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB007933.2, BC112295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG CTTCTTTTAT TGCAGAAAAA GGAATGGACG 
TGGGATGAGA GCAAGATGCT GGTGATGCAG GACCCCATCT ACAGGATCTT CTATGTCTCT 
CATGATTCCC AAGACTTGAA GATCTTCAGC TATATCGCTC GAGATGGTGC CAGCAATATC 
TTCAGGTGTA ACGTCTTTAA ATCCAAGAAG AAGAGCCAAG CTATGAGAAT CGTTCGGACG 
GTGGGGCAGG CCTTTGAGGT CTGCCACAAG CTGAGCCTGC AGCACACGCA GCAGAATGCA 
GATGGCCAGG AAGATGGAGA GAGCGAGAGG AACAGCAACA GCTCAGGAGA CCCAGGCCGC 
CAGCTCACTG GAGCCGAGAG GGCCTCCACG GCCACTGCAG AGGAGACTGA CATCGATGCG 
GTGGAGGTCC CACTTCCAGG GAATGATGTC CTGGAATTCA GCCGAGGTGT GACTGATCTA 
GATGCTGTAG GGAAGGAAGG AGGCTCTCAC ACAGGCTCCA AGGTTTCGCA CCCCCAGGAG 
CCCATGCTGA CAGCCTCACC CAGGATGCTG CTCCCTTCTT CTTCCTCGAA GCCTCCAGGC 
CTGGGCACAG AGACACCGCT GTCCACTCAC CACCAGATGC AGCTCCTCCA GCAGCTCCTC 
CAGCAGCAGC AGCAGCAGAC ACAAGTGGCT GTGGCCCAGG TACACTTGCT GAAGGACCAG 
TTGGCTGCTG AGGCTGCGGC GCGGCTGGAG GCCCAGGCTC GCGTGCATCA GCTTTTGCTG 
CAGAACAAGG ACATGCTCCA GCACATCTCC CTGCTGGTCA AGCAGGTGCA AGAGCTGGAA 
CTGAAGCTGT CAGGACAGAA CGCCATGGGC TCCCAGGACA GCTTGCTGGA GATCACCTTC 
CGCTCCGGAG CCCTGCCCGT GCTCTGTGAC CCCACGACCC CTAAGCCAGA GGACCTGCAT 
TCGCCGCCGC TGGGCGCGGG CTTGGCTGAC TTTGCCCACC CTGCGGGCAG CCCCTTAGGT 
AGGCGCGACT GCTTGGTGAA GCTGGAGTGC TTTCGCTTTC TTCCGCCCGA GGACACCCCG 
CCCCCAGCGC AGGGCGAGGC GCTCCTGGGC GGTCTGGAGC TCATCAAGTT CCGAGAGTCA 
GGCATCGCCT CGGAGTACGA GTCCAACACG GACGAGAGCG AGGAGCGCGA CTCGTGGTCC 
CAGGAGGAGC TGCCGCGCCT GCTGAATGTC CTGCAGAGGC AGGAACTGGG CGACGGCCTG 
GATGATGAGA TCGCCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055512.1
CDS	388..1908
Translation	MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV

Target ORF information:

RefSeq Version	NM_014697.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014697.2

ORF Insert Sequence:

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG CTTCTTTTAT TGCAGAAAAA GGAATGGACG 
TGGGATGAGA GCAAGATGCT GGTGATGCAG GACCCCATCT ACAGGATCTT CTATGTCTCT 
CATGATTCCC AAGACTTGAA GATCTTCAGC TATATCGCTC GAGATGGTGC CAGCAATATC 
TTCAGGTGTA ACGTCTTTAA ATCCAAGAAG AAGAGCCAAG CTATGAGAAT CGTTCGGACG 
GTGGGGCAGG CCTTTGAGGT CTGCCACAAG CTGAGCCTGC AGCACACGCA GCAGAATGCA 
GATGGCCAGG AAGATGGAGA GAGCGAGAGG AACAGCAACA GCTCAGGAGA CCCAGGCCGC 
CAGCTCACTG GAGCCGAGAG GGCCTCCACG GCCACTGCAG AGGAGACTGA CATCGATGCG 
GTGGAGGTCC CACTTCCAGG GAATGATGTC CTGGAATTCA GCCGAGGTGT GACTGATCTA 
GATGCTGTAG GGAAGGAAGG AGGCTCTCAC ACAGGCTCCA AGGTTTCGCA CCCCCAGGAG 
CCCATGCTGA CAGCCTCACC CAGGATGCTG CTCCCTTCTT CTTCCTCGAA GCCTCCAGGC 
CTGGGCACAG AGACACCGCT GTCCACTCAC CACCAGATGC AGCTCCTCCA GCAGCTCCTC 
CAGCAGCAGC AGCAGCAGAC ACAAGTGGCT GTGGCCCAGG TACACTTGCT GAAGGACCAG 
TTGGCTGCTG AGGCTGCGGC GCGGCTGGAG GCCCAGGCTC GCGTGCATCA GCTTTTGCTG 
CAGAACAAGG ACATGCTCCA GCACATCTCC CTGCTGGTCA AGCAGGTGCA AGAGCTGGAA 
CTGAAGCTGT CAGGACAGAA CGCCATGGGC TCCCAGGACA GCTTGCTGGA GATCACCTTC 
CGCTCCGGAG CCCTGCCCGT GCTCTGTGAC CCCACGACCC CTAAGCCAGA GGACCTGCAT 
TCGCCGCCGC TGGGCGCGGG CTTGGCTGAC TTTGCCCACC CTGCGGGCAG CCCCTTAGGT 
AGGCGCGACT GCTTGGTGAA GCTGGAGTGC TTTCGCTTTC TTCCGCCCGA GGACACCCCG 
CCCCCAGCGC AGGGCGAGGC GCTCCTGGGC GGTCTGGAGC TCATCAAGTT CCGAGAGTCA 
GGCATCGCCT CGGAGTACGA GTCCAACACG GACGAGAGCG AGGAGCGCGA CTCGTGGTCC 
CAGGAGGAGC TGCCGCGCCT GCTGAATGTC CTGCAGAGGC AGGAACTGGG CGACGGCCTG 
GATGATGAGA TCGCCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NOS1AP ( NM_014697.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055512.1 Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18983
Clone ID Related Accession (Same CDS sequence)	NM_014697.2 , NM_014697.3
Accession Version	NM_014697.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1521bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590408.15, AB007933.2, BC112295.1 and AL512785.7. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_014697.2. Transcript Variant: This variant (1) encodes the full-length protein (isoform 1). Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB007933.2, BC112295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000361897.10/ ENSP00000355133.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG CTTCTTTTAT TGCAGAAAAA GGAATGGACG 
TGGGATGAGA GCAAGATGCT GGTGATGCAG GACCCCATCT ACAGGATCTT CTATGTCTCT 
CATGATTCCC AAGACTTGAA GATCTTCAGC TATATCGCTC GAGATGGTGC CAGCAATATC 
TTCAGGTGTA ACGTCTTTAA ATCCAAGAAG AAGAGCCAAG CTATGAGAAT CGTTCGGACG 
GTGGGGCAGG CCTTTGAGGT CTGCCACAAG CTGAGCCTGC AGCACACGCA GCAGAATGCA 
GATGGCCAGG AAGATGGAGA GAGCGAGAGG AACAGCAACA GCTCAGGAGA CCCAGGCCGC 
CAGCTCACTG GAGCCGAGAG GGCCTCCACG GCCACTGCAG AGGAGACTGA CATCGATGCG 
GTGGAGGTCC CACTTCCAGG GAATGATGTC CTGGAATTCA GCCGAGGTGT GACTGATCTA 
GATGCTGTAG GGAAGGAAGG AGGCTCTCAC ACAGGCTCCA AGGTTTCGCA CCCCCAGGAG 
CCCATGCTGA CAGCCTCACC CAGGATGCTG CTCCCTTCTT CTTCCTCGAA GCCTCCAGGC 
CTGGGCACAG AGACACCGCT GTCCACTCAC CACCAGATGC AGCTCCTCCA GCAGCTCCTC 
CAGCAGCAGC AGCAGCAGAC ACAAGTGGCT GTGGCCCAGG TACACTTGCT GAAGGACCAG 
TTGGCTGCTG AGGCTGCGGC GCGGCTGGAG GCCCAGGCTC GCGTGCATCA GCTTTTGCTG 
CAGAACAAGG ACATGCTCCA GCACATCTCC CTGCTGGTCA AGCAGGTGCA AGAGCTGGAA 
CTGAAGCTGT CAGGACAGAA CGCCATGGGC TCCCAGGACA GCTTGCTGGA GATCACCTTC 
CGCTCCGGAG CCCTGCCCGT GCTCTGTGAC CCCACGACCC CTAAGCCAGA GGACCTGCAT 
TCGCCGCCGC TGGGCGCGGG CTTGGCTGAC TTTGCCCACC CTGCGGGCAG CCCCTTAGGT 
AGGCGCGACT GCTTGGTGAA GCTGGAGTGC TTTCGCTTTC TTCCGCCCGA GGACACCCCG 
CCCCCAGCGC AGGGCGAGGC GCTCCTGGGC GGTCTGGAGC TCATCAAGTT CCGAGAGTCA 
GGCATCGCCT CGGAGTACGA GTCCAACACG GACGAGAGCG AGGAGCGCGA CTCGTGGTCC 
CAGGAGGAGC TGCCGCGCCT GCTGAATGTC CTGCAGAGGC AGGAACTGGG CGACGGCCTG 
GATGATGAGA TCGCCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055512.1
CDS	488..2008
Translation	MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKLLLLQKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV

Target ORF information:

RefSeq Version	NM_014697.3
Organism	Homo sapiens(human)
Definition	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014697.3

ORF Insert Sequence:

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG CTTCTTTTAT TGCAGAAAAA GGAATGGACG 
TGGGATGAGA GCAAGATGCT GGTGATGCAG GACCCCATCT ACAGGATCTT CTATGTCTCT 
CATGATTCCC AAGACTTGAA GATCTTCAGC TATATCGCTC GAGATGGTGC CAGCAATATC 
TTCAGGTGTA ACGTCTTTAA ATCCAAGAAG AAGAGCCAAG CTATGAGAAT CGTTCGGACG 
GTGGGGCAGG CCTTTGAGGT CTGCCACAAG CTGAGCCTGC AGCACACGCA GCAGAATGCA 
GATGGCCAGG AAGATGGAGA GAGCGAGAGG AACAGCAACA GCTCAGGAGA CCCAGGCCGC 
CAGCTCACTG GAGCCGAGAG GGCCTCCACG GCCACTGCAG AGGAGACTGA CATCGATGCG 
GTGGAGGTCC CACTTCCAGG GAATGATGTC CTGGAATTCA GCCGAGGTGT GACTGATCTA 
GATGCTGTAG GGAAGGAAGG AGGCTCTCAC ACAGGCTCCA AGGTTTCGCA CCCCCAGGAG 
CCCATGCTGA CAGCCTCACC CAGGATGCTG CTCCCTTCTT CTTCCTCGAA GCCTCCAGGC 
CTGGGCACAG AGACACCGCT GTCCACTCAC CACCAGATGC AGCTCCTCCA GCAGCTCCTC 
CAGCAGCAGC AGCAGCAGAC ACAAGTGGCT GTGGCCCAGG TACACTTGCT GAAGGACCAG 
TTGGCTGCTG AGGCTGCGGC GCGGCTGGAG GCCCAGGCTC GCGTGCATCA GCTTTTGCTG 
CAGAACAAGG ACATGCTCCA GCACATCTCC CTGCTGGTCA AGCAGGTGCA AGAGCTGGAA 
CTGAAGCTGT CAGGACAGAA CGCCATGGGC TCCCAGGACA GCTTGCTGGA GATCACCTTC 
CGCTCCGGAG CCCTGCCCGT GCTCTGTGAC CCCACGACCC CTAAGCCAGA GGACCTGCAT 
TCGCCGCCGC TGGGCGCGGG CTTGGCTGAC TTTGCCCACC CTGCGGGCAG CCCCTTAGGT 
AGGCGCGACT GCTTGGTGAA GCTGGAGTGC TTTCGCTTTC TTCCGCCCGA GGACACCCCG 
CCCCCAGCGC AGGGCGAGGC GCTCCTGGGC GGTCTGGAGC TCATCAAGTT CCGAGAGTCA 
GGCATCGCCT CGGAGTACGA GTCCAACACG GACGAGAGCG AGGAGCGCGA CTCGTGGTCC 
CAGGAGGAGC TGCCGCGCCT GCTGAATGTC CTGCAGAGGC AGGAACTGGG CGACGGCCTG 
GATGATGAGA TCGCCGTGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NOS1AP ( NM_001126060.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001119532.2 Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09164
Clone ID Related Accession (Same CDS sequence)	NM_001126060.1
Accession Version	NM_001126060.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 636bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Homo sapiens(human)
Product	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY841899.1 and AL512785.7. Transcript Variant: This variant (2) consists of the two terminal exons of variant 1 and results in a protein (isoform 2) that is significantly shorter than isoform 1(see PMID: 16146415). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY841899.1, SRR1660803.232324.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGTCCCTCT CTTCTCTCTG TCCTGTCTTC TCTGCCGCTG CCTCTTCTCT GCAGGTACAC 
TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG 
CATCAGCTTT TGCTGCAGAA CAAGGACATG CTCCAGCACA TCTCCCTGCT GGTCAAGCAG 
GTGCAAGAGC TGGAACTGAA GCTGTCAGGA CAGAACGCCA TGGGCTCCCA GGACAGCTTG 
CTGGAGATCA CCTTCCGCTC CGGAGCCCTG CCCGTGCTCT GTGACCCCAC GACCCCTAAG 
CCAGAGGACC TGCATTCGCC GCCGCTGGGC GCGGGCTTGG CTGACTTTGC CCACCCTGCG 
GGCAGCCCCT TAGGTAGGCG CGACTGCTTG GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG 
CCCGAGGACA CCCCGCCCCC AGCGCAGGGC GAGGCGCTCC TGGGCGGTCT GGAGCTCATC 
AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG TACGAGTCCA ACACGGACGA GAGCGAGGAG 
CGCGACTCGT GGTCCCAGGA GGAGCTGCCG CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA 
CTGGGCGACG GCCTGGATGA TGAGATCGCC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001119532.2
CDS	2368..3003
Translation	MSLSSLCPVFSAAASSLQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV

Target ORF information:

RefSeq Version	NM_001126060.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001126060.1

ORF Insert Sequence:

ATGTCCCTCT CTTCTCTCTG TCCTGTCTTC TCTGCCGCTG CCTCTTCTCT GCAGGTACAC 
TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG 
CATCAGCTTT TGCTGCAGAA CAAGGACATG CTCCAGCACA TCTCCCTGCT GGTCAAGCAG 
GTGCAAGAGC TGGAACTGAA GCTGTCAGGA CAGAACGCCA TGGGCTCCCA GGACAGCTTG 
CTGGAGATCA CCTTCCGCTC CGGAGCCCTG CCCGTGCTCT GTGACCCCAC GACCCCTAAG 
CCAGAGGACC TGCATTCGCC GCCGCTGGGC GCGGGCTTGG CTGACTTTGC CCACCCTGCG 
GGCAGCCCCT TAGGTAGGCG CGACTGCTTG GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG 
CCCGAGGACA CCCCGCCCCC AGCGCAGGGC GAGGCGCTCC TGGGCGGTCT GGAGCTCATC 
AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG TACGAGTCCA ACACGGACGA GAGCGAGGAG 
CGCGACTCGT GGTCCCAGGA GGAGCTGCCG CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA 
CTGGGCGACG GCCTGGATGA TGAGATCGCC GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NOS1AP ( NM_001164757.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001158229.1 Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.

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CloneID	OHu10640
Clone ID Related Accession (Same CDS sequence)	NM_001164757.1 , NM_001164757.2
Accession Version	NM_001164757.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AB007933.2, BC143771.1 and AL512785.7. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1, that results in a shorter protein (isoform 3), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041382.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG AAAAAGGAAT GGACGTGGGA TGAGAGCAAG 
ATGCTGGTGA TGCAGGACCC CATCTACAGG ATCTTCTATG TCTCTCATGA TTCCCAAGAC 
TTGAAGATCT TCAGCTATAT CGCTCGAGAT GGTGCCAGCA ATATCTTCAG GTGTAACGTC 
TTTAAATCCA AGAAGAAGAG CCAAGCTATG AGAATCGTTC GGACGGTGGG GCAGGCCTTT 
GAGGTCTGCC ACAAGCTGAG CCTGCAGCAC ACGCAGCAGA ATGCAGATGG CCAGGAAGAT 
GGAGAGAGCG AGAGGAACAG CAACAGCTCA GGAGACCCAG GCCGCCAGCT CACTGGAGCC 
GAGAGGGCCT CCACGGCCAC TGCAGAGGAG ACTGACATCG ATGCGGTGGA GGTCCCACTT 
CCAGGGAATG ATGTCCTGGA ATTCAGCCGA GGTGTGACTG ATCTAGATGC TGTAGGGAAG 
GAAGGAGGCT CTCACACAGG CTCCAAGGTT TCGCACCCCC AGGAGCCCAT GCTGACAGCC 
TCACCCAGGA TGCTGCTCCC TTCTTCTTCC TCGAAGCCTC CAGGCCTGGG CACAGAGACA 
CCGCTGTCCA CTCACCACCA GATGCAGCTC CTCCAGCAGC TCCTCCAGCA GCAGCAGCAG 
CAGACACAAG TGGCTGTGGC CCAGGTACAC TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT 
GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG CATCAGCTTT TGCTGCAGAA CAAGGACATG 
CTCCAGCACA TCTCCCTGCT GGTCAAGCAG GTGCAAGAGC TGGAACTGAA GCTGTCAGGA 
CAGAACGCCA TGGGCTCCCA GGACAGCTTG CTGGAGATCA CCTTCCGCTC CGGAGCCCTG 
CCCGTGCTCT GTGACCCCAC GACCCCTAAG CCAGAGGACC TGCATTCGCC GCCGCTGGGC 
GCGGGCTTGG CTGACTTTGC CCACCCTGCG GGCAGCCCCT TAGGTAGGCG CGACTGCTTG 
GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG CCCGAGGACA CCCCGCCCCC AGCGCAGGGC 
GAGGCGCTCC TGGGCGGTCT GGAGCTCATC AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG 
TACGAGTCCA ACACGGACGA GAGCGAGGAG CGCGACTCGT GGTCCCAGGA GGAGCTGCCG 
CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA CTGGGCGACG GCCTGGATGA TGAGATCGCC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001158229.1
CDS	388..1893
Translation	MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV

Target ORF information:

RefSeq Version	NM_001164757.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164757.1

ORF Insert Sequence:

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG AAAAAGGAAT GGACGTGGGA TGAGAGCAAG 
ATGCTGGTGA TGCAGGACCC CATCTACAGG ATCTTCTATG TCTCTCATGA TTCCCAAGAC 
TTGAAGATCT TCAGCTATAT CGCTCGAGAT GGTGCCAGCA ATATCTTCAG GTGTAACGTC 
TTTAAATCCA AGAAGAAGAG CCAAGCTATG AGAATCGTTC GGACGGTGGG GCAGGCCTTT 
GAGGTCTGCC ACAAGCTGAG CCTGCAGCAC ACGCAGCAGA ATGCAGATGG CCAGGAAGAT 
GGAGAGAGCG AGAGGAACAG CAACAGCTCA GGAGACCCAG GCCGCCAGCT CACTGGAGCC 
GAGAGGGCCT CCACGGCCAC TGCAGAGGAG ACTGACATCG ATGCGGTGGA GGTCCCACTT 
CCAGGGAATG ATGTCCTGGA ATTCAGCCGA GGTGTGACTG ATCTAGATGC TGTAGGGAAG 
GAAGGAGGCT CTCACACAGG CTCCAAGGTT TCGCACCCCC AGGAGCCCAT GCTGACAGCC 
TCACCCAGGA TGCTGCTCCC TTCTTCTTCC TCGAAGCCTC CAGGCCTGGG CACAGAGACA 
CCGCTGTCCA CTCACCACCA GATGCAGCTC CTCCAGCAGC TCCTCCAGCA GCAGCAGCAG 
CAGACACAAG TGGCTGTGGC CCAGGTACAC TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT 
GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG CATCAGCTTT TGCTGCAGAA CAAGGACATG 
CTCCAGCACA TCTCCCTGCT GGTCAAGCAG GTGCAAGAGC TGGAACTGAA GCTGTCAGGA 
CAGAACGCCA TGGGCTCCCA GGACAGCTTG CTGGAGATCA CCTTCCGCTC CGGAGCCCTG 
CCCGTGCTCT GTGACCCCAC GACCCCTAAG CCAGAGGACC TGCATTCGCC GCCGCTGGGC 
GCGGGCTTGG CTGACTTTGC CCACCCTGCG GGCAGCCCCT TAGGTAGGCG CGACTGCTTG 
GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG CCCGAGGACA CCCCGCCCCC AGCGCAGGGC 
GAGGCGCTCC TGGGCGGTCT GGAGCTCATC AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG 
TACGAGTCCA ACACGGACGA GAGCGAGGAG CGCGACTCGT GGTCCCAGGA GGAGCTGCCG 
CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA CTGGGCGACG GCCTGGATGA TGAGATCGCC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NOS1AP ( NM_001164757.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001158229.1 Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.

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CloneID	OHu10640
Clone ID Related Accession (Same CDS sequence)	NM_001164757.1 , NM_001164757.2
Accession Version	NM_001164757.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1506bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL590408.15, AB007933.2, BC143771.1 and AL512785.7. On May 31, 2019 this sequence version replaced NM_001164757.1. Transcript Variant: This variant (3) uses an alternate in-frame splice site in the coding region, compared to variant 1, that results in a shorter protein (isoform 3), compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from transcript and genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC041382.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END##

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG AAAAAGGAAT GGACGTGGGA TGAGAGCAAG 
ATGCTGGTGA TGCAGGACCC CATCTACAGG ATCTTCTATG TCTCTCATGA TTCCCAAGAC 
TTGAAGATCT TCAGCTATAT CGCTCGAGAT GGTGCCAGCA ATATCTTCAG GTGTAACGTC 
TTTAAATCCA AGAAGAAGAG CCAAGCTATG AGAATCGTTC GGACGGTGGG GCAGGCCTTT 
GAGGTCTGCC ACAAGCTGAG CCTGCAGCAC ACGCAGCAGA ATGCAGATGG CCAGGAAGAT 
GGAGAGAGCG AGAGGAACAG CAACAGCTCA GGAGACCCAG GCCGCCAGCT CACTGGAGCC 
GAGAGGGCCT CCACGGCCAC TGCAGAGGAG ACTGACATCG ATGCGGTGGA GGTCCCACTT 
CCAGGGAATG ATGTCCTGGA ATTCAGCCGA GGTGTGACTG ATCTAGATGC TGTAGGGAAG 
GAAGGAGGCT CTCACACAGG CTCCAAGGTT TCGCACCCCC AGGAGCCCAT GCTGACAGCC 
TCACCCAGGA TGCTGCTCCC TTCTTCTTCC TCGAAGCCTC CAGGCCTGGG CACAGAGACA 
CCGCTGTCCA CTCACCACCA GATGCAGCTC CTCCAGCAGC TCCTCCAGCA GCAGCAGCAG 
CAGACACAAG TGGCTGTGGC CCAGGTACAC TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT 
GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG CATCAGCTTT TGCTGCAGAA CAAGGACATG 
CTCCAGCACA TCTCCCTGCT GGTCAAGCAG GTGCAAGAGC TGGAACTGAA GCTGTCAGGA 
CAGAACGCCA TGGGCTCCCA GGACAGCTTG CTGGAGATCA CCTTCCGCTC CGGAGCCCTG 
CCCGTGCTCT GTGACCCCAC GACCCCTAAG CCAGAGGACC TGCATTCGCC GCCGCTGGGC 
GCGGGCTTGG CTGACTTTGC CCACCCTGCG GGCAGCCCCT TAGGTAGGCG CGACTGCTTG 
GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG CCCGAGGACA CCCCGCCCCC AGCGCAGGGC 
GAGGCGCTCC TGGGCGGTCT GGAGCTCATC AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG 
TACGAGTCCA ACACGGACGA GAGCGAGGAG CGCGACTCGT GGTCCCAGGA GGAGCTGCCG 
CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA CTGGGCGACG GCCTGGATGA TGAGATCGCC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001158229.1
CDS	488..1993
Translation	MPSKTKYNLVDDGHDLRIPLHNEDAFQHGICFEAKYVGSLDVPRPNSRVEIVAAMRRIRYEFKAKNIKKKKVSIMVSVDGVKVILKKKKKKKEWTWDESKMLVMQDPIYRIFYVSHDSQDLKIFSYIARDGASNIFRCNVFKSKKKSQAMRIVRTVGQAFEVCHKLSLQHTQQNADGQEDGESERNSNSSGDPGRQLTGAERASTATAEETDIDAVEVPLPGNDVLEFSRGVTDLDAVGKEGGSHTGSKVSHPQEPMLTASPRMLLPSSSSKPPGLGTETPLSTHHQMQLLQQLLQQQQQQTQVAVAQVHLLKDQLAAEAAARLEAQARVHQLLLQNKDMLQHISLLVKQVQELELKLSGQNAMGSQDSLLEITFRSGALPVLCDPTTPKPEDLHSPPLGAGLADFAHPAGSPLGRRDCLVKLECFRFLPPEDTPPPAQGEALLGGLELIKFRESGIASEYESNTDESEERDSWSQEELPRLLNVLQRQELGDGLDDEIAV

Target ORF information:

RefSeq Version	NM_001164757.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nitric oxide synthase 1 adaptor protein (NOS1AP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001164757.2

ORF Insert Sequence:

ATGCCTAGCA AAACCAAGTA CAACCTTGTG GACGATGGGC ACGACCTGCG GATCCCCTTG 
CACAACGAGG ACGCCTTCCA GCACGGCATC TGCTTTGAGG CCAAGTACGT AGGAAGCCTG 
GACGTGCCAA GGCCCAACAG CAGGGTGGAG ATCGTGGCTG CCATGCGCCG GATACGGTAT 
GAGTTTAAAG CCAAGAACAT CAAGAAGAAG AAAGTGAGCA TTATGGTTTC AGTGGATGGA 
GTGAAAGTGA TTCTGAAGAA GAAGAAAAAG AAAAAGGAAT GGACGTGGGA TGAGAGCAAG 
ATGCTGGTGA TGCAGGACCC CATCTACAGG ATCTTCTATG TCTCTCATGA TTCCCAAGAC 
TTGAAGATCT TCAGCTATAT CGCTCGAGAT GGTGCCAGCA ATATCTTCAG GTGTAACGTC 
TTTAAATCCA AGAAGAAGAG CCAAGCTATG AGAATCGTTC GGACGGTGGG GCAGGCCTTT 
GAGGTCTGCC ACAAGCTGAG CCTGCAGCAC ACGCAGCAGA ATGCAGATGG CCAGGAAGAT 
GGAGAGAGCG AGAGGAACAG CAACAGCTCA GGAGACCCAG GCCGCCAGCT CACTGGAGCC 
GAGAGGGCCT CCACGGCCAC TGCAGAGGAG ACTGACATCG ATGCGGTGGA GGTCCCACTT 
CCAGGGAATG ATGTCCTGGA ATTCAGCCGA GGTGTGACTG ATCTAGATGC TGTAGGGAAG 
GAAGGAGGCT CTCACACAGG CTCCAAGGTT TCGCACCCCC AGGAGCCCAT GCTGACAGCC 
TCACCCAGGA TGCTGCTCCC TTCTTCTTCC TCGAAGCCTC CAGGCCTGGG CACAGAGACA 
CCGCTGTCCA CTCACCACCA GATGCAGCTC CTCCAGCAGC TCCTCCAGCA GCAGCAGCAG 
CAGACACAAG TGGCTGTGGC CCAGGTACAC TTGCTGAAGG ACCAGTTGGC TGCTGAGGCT 
GCGGCGCGGC TGGAGGCCCA GGCTCGCGTG CATCAGCTTT TGCTGCAGAA CAAGGACATG 
CTCCAGCACA TCTCCCTGCT GGTCAAGCAG GTGCAAGAGC TGGAACTGAA GCTGTCAGGA 
CAGAACGCCA TGGGCTCCCA GGACAGCTTG CTGGAGATCA CCTTCCGCTC CGGAGCCCTG 
CCCGTGCTCT GTGACCCCAC GACCCCTAAG CCAGAGGACC TGCATTCGCC GCCGCTGGGC 
GCGGGCTTGG CTGACTTTGC CCACCCTGCG GGCAGCCCCT TAGGTAGGCG CGACTGCTTG 
GTGAAGCTGG AGTGCTTTCG CTTTCTTCCG CCCGAGGACA CCCCGCCCCC AGCGCAGGGC 
GAGGCGCTCC TGGGCGGTCT GGAGCTCATC AAGTTCCGAG AGTCAGGCAT CGCCTCGGAG 
TACGAGTCCA ACACGGACGA GAGCGAGGAG CGCGACTCGT GGTCCCAGGA GGAGCTGCCG 
CGCCTGCTGA ATGTCCTGCA GAGGCAGGAA CTGGGCGACG GCCTGGATGA TGAGATCGCC 
GTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The interaction of NOS1AP, DISC1, DAOA, and GSK3B confers susceptibility of early-onset schizophrenia in Chinese Han population.
Progress in neuro-psychopharmacology & biological psychiatry81187-193(2018 Feb)
Hu G,Yang C,Zhao L,Fan Y,Lv Q,Zhao J,Zhu M,Guo X,Bao C,Xu A,Jie Y,Jiang Y,Zhang C,Yu S,Wang Z,Li Z,Yi Z

The genetic variation rs12143842 in NOS1AP increases idiopathic ventricular tachycardia risk in Chinese Han populations.
Scientific reports7(1)8356(2017 Aug)
Zhang R,Chen F,Yu H,Gao L,Yin X,Dong Y,Yang Y,Xia Y

Sex is a moderator of the association between NOS1AP sequence variants and QTc in two long QT syndrome founder populations: a pedigree-based measured genotype association analysis.
BMC medical genetics18(1)74(2017 07)
Winbo A,Stattin EL,Westin IM,Norberg A,Persson J,Jensen SM,Rydberg A

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NOS1AP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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