ACYP1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACYP1
Entrez Gene ID	97
Full Name	acylphosphatase 1
Synonyms	ACYPE
General protein information	Preferred Names acylphosphatase 1 Names acylphosphatase-1 acylphosphatase 1, erythrocyte (common) type acylphosphatase, erythrocyte isozyme acylphosphatase, organ-common type isozyme acylphosphate phosphohydrolase 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 14 Map Location: 14q24.3
Summary	This gene is a member of the acylphosphatase family. The encoded protein is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated and described based on their tissue localization: erythrocyte (common) type acylphosphatase encoded by this gene, and muscle type acylphosphatase. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014].
Disorder MIM:	600875

mRNA and Protein(s)

mRNA	Protein	Name
NM_001302616.2	NP_001289545.1	acylphosphatase-1 isoform a
NM_001107.4	NP_001098.1	acylphosphatase-1 isoform a
NM_001302617.2	NP_001289546.1	acylphosphatase-1 isoform c precursor
NM_001302616.1	NP_001289545.1	acylphosphatase-1 isoform a
NM_001302617.1	NP_001289546.1	acylphosphatase-1 isoform c precursor
NM_001107.5	NP_001098.1	acylphosphatase-1 isoform a

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Acyp1	NP_079697.1
Bos taurus (cattle)	ACYP1	NP_001039447.1
Rattus norvegicus (Norway rat)	Acyp1	NP_001100216.1
Gallus gallus (chicken)	ACYP1	NP_001161477.1
Xenopus tropicalis (tropical clawed frog)	acyp1	NP_001016160.1
	ACYP1	XP_001090451.1
Canis lupus familiaris (dog)	ACYP1	XP_537512.3
Homo sapiens (human)	ACYP1	NP_001098.1
Pan troglodytes (chimpanzee)	ACYP1	XP_001159367.1
Danio rerio (zebrafish)	acyp1	NP_001116321.1

Gene Ontology
Bibliography

Related articles in PubMed

ACYP1 gene possesses two alternative splicing forms that induce apoptosis.
Degl'Innocenti D, Marzocchini R, Malentacchi F, Ramazzotti M, Raugei G, Ramponi G
IUBMB life56(1)29-33(2004 Jan)

A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase.
Paoli P, Pazzagli L, Giannoni E, Caselli A, Manao G, Camici G, Ramponi G
The Journal of biological chemistry278(1)194-9(2003 Jan)

Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants.
Wistow G, Bernstein SL, Wyatt MK, Behal A, Touchman JW, Bouffard G, Smith D, Peterson K
Molecular vision8171-84(2002 Jun)

Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3.
Fiaschi T, Marzella R, Veggi D, Marzocchini R, Raugei G, Rocchi M, Ramponi G
Cytogenetics and cell genetics81(3-4)235-6(1998)

Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase.
Fiaschi T, Raugei G, Marzocchini R, Chiarugi P, Cirri P, Ramponi G
FEBS letters367(2)145-8(1995 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

two products of the ACYP1 gene are characterized as the result of alternative splicing in which an extra 79 bp long exon is inserted between the two known exons
Title: ACYP1 gene possesses two alternative splicing forms that induce apoptosis.

Data show that CT acylphosphatase catalyzes the hydrolysis of aryl phosphates and acyl phosphates by two different mechanisms.
Title: A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase.

The following ACYP1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACYP1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu29769	NM_001107.5 Latest version!	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu29769	NM_001302616.2 Latest version!	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu48016	NM_001302617.2 Latest version!	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu29769	NM_001302616.1	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu48016	NM_001302617.1	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
OHu29769	NM_001107.4	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACYP1 ( NM_001302616.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001289545.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu29769
Clone ID Related Accession (Same CDS sequence)	NM_001302616.2 , NM_001107.4 , NM_001302616.1 , NM_001107.5
Accession Version	NM_001302616.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP316920.1, AK312101.1, BC035568.1 and X84194.1. On May 31, 2019 this sequence version replaced NM_001302616.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants 1 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BP316920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465401 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289545.1
CDS	62..361
Translation	MAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001302616.2
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302616.2

ORF Insert Sequence:

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACYP1 ( NM_001107.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001098.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29769
Clone ID Related Accession (Same CDS sequence)	NM_001302616.2 , NM_001107.4 , NM_001302616.1 , NM_001107.5
Accession Version	NM_001107.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB071115.1, AK312101.1, BC035568.1, X84194.1 and BE467248.1. On Oct 31, 2014 this sequence version replaced NM_001107.3. Transcript Variant: This variant (1) encodes isoform a. Both variants 1 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: DB071115.1, SRR1163658.387581.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001098.1
CDS	105..404
Translation	MAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001107.4
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107.4

ORF Insert Sequence:

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACYP1 ( NM_001302616.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001289545.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu29769
Clone ID Related Accession (Same CDS sequence)	NM_001302616.2 , NM_001107.4 , NM_001302616.1 , NM_001107.5
Accession Version	NM_001302616.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB071115.1, BP316920.1, AK312101.1, BC035568.1, X84194.1 and BE467248.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Both variants 1 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BP316920.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465401 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289545.1
CDS	87..386
Translation	MAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001302616.1
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302616.1

ORF Insert Sequence:

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACYP1 ( NM_001107.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_001098.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu29769
Clone ID Related Accession (Same CDS sequence)	NM_001302616.2 , NM_001107.4 , NM_001302616.1 , NM_001107.5
Accession Version	NM_001107.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK312101.1, BC035568.1 and X84194.1. On Nov 22, 2018 this sequence version replaced NM_001107.4. Transcript Variant: This variant (1) encodes isoform a. Both variants 1 and 3 encode the same protein. ##Evidence-Data-START## Transcript exon combination :: BC035568.1, SRR1163655.666173.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000238618.8/ ENSP00000238618.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001098.1
CDS	80..379
Translation	MAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001107.5
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001107.5

ORF Insert Sequence:

ATGGCAGAAG GAAACACCCT GATATCAGTG GATTATGAAA TTTTTGGGAA GGTGCAAGGG 
GTGTTTTTCC GTAAGCATAC TCAGGCTGAG GGTAAAAAGC TGGGATTGGT AGGCTGGGTC 
CAGAACACTG ACCGGGGCAC AGTGCAAGGA CAATTGCAAG GTCCCATCTC CAAGGTGCGT 
CATATGCAGG AATGGCTTGA AACAAGAGGA AGTCCTAAAT CACACATCGA CAAAGCAAAC 
TTCAACAATG AAAAAGTCAT CTTGAAGTTG GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACYP1 ( NM_001302617.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001289546.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu48016
Clone ID Related Accession (Same CDS sequence)	NM_001302617.2 , NM_001302617.1
Accession Version	NM_001302617.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-14
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL049780.4, CD675334.1 and BX104912.1. On May 31, 2019 this sequence version replaced NM_001302617.1. Transcript Variant: This variant (4) uses an upstream alternate 5' terminal exon and lacks an alternate exon, compared to variant 1. The encoded isoform (c) has a longer N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: DRR138525.103104.1, DRR138528.436590.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCGT CCGCCCGCCT GGCGGGAGCG GGGCTGCTGC TGGCCTTTCT CCGCGCGCTC 
GGCTGCGCTG GGCGGGCCCC AGGTTTGAGC ATGGCAGAAG GAAACACCCT GATATCAGTG 
GATTATGAAA TTTTTGGGAA GGTGCAAGGG GTGTTTTTCC GTAAGCATAC TCAGGCTGAG 
GGTAAAAAGC TGGGATTGGT AGGCTGGGTC CAGAACACTG ACCGGGGCAC AGTGCAAGGA 
CAATTGCAAG GTCCCATCTC CAAGGTGCGT CATATGCAGG AATGGCTTGA AACAAGAGGA 
AGTCCTAAAT CACACATCGA CAAAGCAAAC TTCAACAATG AAAAAGTCAT CTTGAAGTTG 
GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289546.1
CDS	200..589
Translation	MPASARLAGAGLLLAFLRALGCAGRAPGLSMAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001302617.2
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302617.2

ORF Insert Sequence:

ATGCCGGCGT CCGCCCGCCT GGCGGGAGCG GGGCTGCTGC TGGCCTTTCT CCGCGCGCTC 
GGCTGCGCTG GGCGGGCCCC AGGTTTGAGC ATGGCAGAAG GAAACACCCT GATATCAGTG 
GATTATGAAA TTTTTGGGAA GGTGCAAGGG GTGTTTTTCC GTAAGCATAC TCAGGCTGAG 
GGTAAAAAGC TGGGATTGGT AGGCTGGGTC CAGAACACTG ACCGGGGCAC AGTGCAAGGA 
CAATTGCAAG GTCCCATCTC CAAGGTGCGT CATATGCAGG AATGGCTTGA AACAAGAGGA 
AGTCCTAAAT CACACATCGA CAAAGCAAAC TTCAACAATG AAAAAGTCAT CTTGAAGTTG 
GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACYP1 ( NM_001302617.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001289546.1 Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu48016
Clone ID Related Accession (Same CDS sequence)	NM_001302617.2 , NM_001302617.1
Accession Version	NM_001302617.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 390bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-23
Organism	Homo sapiens(human)
Product	acylphosphatase-1 isoform c precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CD675334.1, BX104912.1 and BE467248.1. On Oct 31, 2014 this sequence version replaced XM_005268240.1. Transcript Variant: This variant (4) uses an upstream alternate 5' terminal exon and lacks an alternate exon, compared to variant 1. The encoded isoform (c) has a longer N-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: BQ574064.1, CD675334.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGGCGT CCGCCCGCCT GGCGGGAGCG GGGCTGCTGC TGGCCTTTCT CCGCGCGCTC 
GGCTGCGCTG GGCGGGCCCC AGGTTTGAGC ATGGCAGAAG GAAACACCCT GATATCAGTG 
GATTATGAAA TTTTTGGGAA GGTGCAAGGG GTGTTTTTCC GTAAGCATAC TCAGGCTGAG 
GGTAAAAAGC TGGGATTGGT AGGCTGGGTC CAGAACACTG ACCGGGGCAC AGTGCAAGGA 
CAATTGCAAG GTCCCATCTC CAAGGTGCGT CATATGCAGG AATGGCTTGA AACAAGAGGA 
AGTCCTAAAT CACACATCGA CAAAGCAAAC TTCAACAATG AAAAAGTCAT CTTGAAGTTG 
GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001289546.1
CDS	193..582
Translation	MPASARLAGAGLLLAFLRALGCAGRAPGLSMAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVRHMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK

Target ORF information:

RefSeq Version	NM_001302617.1
Organism	Homo sapiens(human)
Definition	Homo sapiens acylphosphatase 1 (ACYP1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001302617.1

ORF Insert Sequence:

ATGCCGGCGT CCGCCCGCCT GGCGGGAGCG GGGCTGCTGC TGGCCTTTCT CCGCGCGCTC 
GGCTGCGCTG GGCGGGCCCC AGGTTTGAGC ATGGCAGAAG GAAACACCCT GATATCAGTG 
GATTATGAAA TTTTTGGGAA GGTGCAAGGG GTGTTTTTCC GTAAGCATAC TCAGGCTGAG 
GGTAAAAAGC TGGGATTGGT AGGCTGGGTC CAGAACACTG ACCGGGGCAC AGTGCAAGGA 
CAATTGCAAG GTCCCATCTC CAAGGTGCGT CATATGCAGG AATGGCTTGA AACAAGAGGA 
AGTCCTAAAT CACACATCGA CAAAGCAAAC TTCAACAATG AAAAAGTCAT CTTGAAGTTG 
GATTACTCAG ACTTCCAAAT TGTAAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

ACYP1 gene possesses two alternative splicing forms that induce apoptosis.
IUBMB life56(1)29-33(2004 Jan)
Degl'Innocenti D,Marzocchini R,Malentacchi F,Ramazzotti M,Raugei G,Ramponi G

A nucleophilic catalysis step is involved in the hydrolysis of aryl phosphate monoesters by human CT acylphosphatase.
The Journal of biological chemistry278(1)194-9(2003 Jan)
Paoli P,Pazzagli L,Giannoni E,Caselli A,Manao G,Camici G,Ramponi G

Expressed sequence tag analysis of adult human lens for the NEIBank Project: over 2000 non-redundant transcripts, novel genes and splice variants.
Molecular vision8171-84(2002 Jun)
Wistow G,Bernstein SL,Wyatt MK,Behal A,Touchman JW,Bouffard G,Smith D,Peterson K

Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3.
Cytogenetics and cell genetics81(3-4)235-6(1998)
Fiaschi T,Marzella R,Veggi D,Marzocchini R,Raugei G,Rocchi M,Ramponi G

Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase.
FEBS letters367(2)145-8(1995 Jun)
Fiaschi T,Raugei G,Marzocchini R,Chiarugi P,Cirri P,Ramponi G

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ACYP1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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