UBE3C cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UBE3C
Entrez Gene ID	9690
Full Name	ubiquitin protein ligase E3C
Synonyms	HECTH2
General protein information	Preferred Names ubiquitin protein ligase E3C Names ubiquitin-protein ligase E3C HECT-type ubiquitin transferase E3C ubiquitin-protein isopeptide ligase (E3)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q36.3
Disorder MIM:	614454

mRNA and Protein(s)

mRNA	Protein	Name
XM_017012818.1	XP_016868307.1	ubiquitin-protein ligase E3C isoform X1
NM_014671.3	NP_055486.2	ubiquitin-protein ligase E3C
NM_014671.2	NP_055486.2	ubiquitin-protein ligase E3C
XM_005249564.4	XP_005249621.1	ubiquitin-protein ligase E3C isoform X2

Pathways from BioSystems

Homologies

	UBE3C	XP_002803585.1
Canis lupus familiaris (dog)	UBE3C	XP_539937.2
Pan troglodytes (chimpanzee)	UBE3C	XP_528010.3
Drosophila melanogaster (fruit fly)	CG3356	NP_611896.1
Gallus gallus (chicken)	UBE3C	NP_001026138.1
Bos taurus (cattle)	UBE3C	NP_001179117.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011474	XP_317832.4
Homo sapiens (human)	UBE3C	NP_055486.2
Mus musculus (house mouse)	Ube3c	NP_598668.1
Rattus norvegicus (Norway rat)	Ube3c	XP_006235923.1
Danio rerio (zebrafish)	ube3c	NP_956767.1
Xenopus tropicalis (tropical clawed frog)	ube3c	NP_001072518.1

Gene Ontology
Bibliography

Related articles in PubMed

MiR-542-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting UBE3C.
Tao J, Liu Z, Wang Y, Wang L, Yao B, Li Q, Wang C, Tu K, Liu Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie93420-428(2017 Sep)

Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c.
Kuo CL, Goldberg AL
Proceedings of the National Academy of Sciences of the United States of America114(17)E3404-E3413(2017 Apr)

The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI).
Sun Y, Jia X, Gao Q, Liu X, Hou L
IUBMB life69(1)16-21(2017 01)

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells.
Tang L, Yi XM, Chen J, Chen FJ, Lou W, Gao YL, Zhou J, Su LN, Xu X, Lu JQ, Ma J, Yu N, Ding YF
Oncotarget7(13)15738-46(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Ectopic overexpression of UBE4A, but not UBE3C, in cells was downregulated in vitro migration and invasion in these cells. Cumulatively, our data reveals a novel post-translational regulatory mechanism of regulating ILEI1 expression, a protein required for metastatic progression in prostate cancer cells
Title: The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI).

UBE3C promotes melanoma progression, possibly by inducing epithelial-mesenchymal transition in melanoma cells
Title: Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells.

data reveal that high UBE3C expression contributes to glioma progression by ubiquitination and degradation of ANXA7, and thus presents a novel and promising target for glioma therapy.
Title: Ubiquitin-protein ligase E3C promotes glioma progression by mediating the ubiquitination and degrading of Annexin A7.

these observations suggest that UBE3C plays an important role in RCC development and progression, and UBE3C may be a novel target for prevention and treatment of ccRCC.
Title: UBE3C promotes growth and metastasis of renal cell carcinoma via activating Wnt/?-catenin pathway.

UBE3C is a mutant candidate oncogene involved in tumor development and progression of hepatocellular carcinoma.
Title: Clinical significance of the ubiquitin ligase UBE3C in hepatocellular carcinoma revealed by exome sequencing.

The following UBE3C gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UBE3C cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09188	NM_014671.3 Latest version!	Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$762.30 $1089.00
OHu41879	XM_005249564.4 Latest version!	Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu63161	XM_017012818.1 Latest version!	Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
View Old Accession Versions >>
OHu09188	NM_014671.2	Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$762.30 $1089.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UBE3C ( NM_014671.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_055486.2 Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.

Price & Availability↑

CloneID	OHu09188
Clone ID Related Accession (Same CDS sequence)	NM_014671.3 , NM_014671.2
Accession Version	NM_014671.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-10
Organism	Homo sapiens(human)
Product	ubiquitin-protein ligase E3C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC004898.3, DB454915.1, D13635.1, DB085748.1, AK127280.1, AA596042.1 and CD366848.1. On Nov 22, 2018 this sequence version replaced NM_014671.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D13635.1, SRR1660805.199761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000348165.10/ ENSP00000309198.8 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
GAAGAAAGGC GAAGGTTGAA AAATGCAATA ATTATCCAGT CATTTATTCG AGGCTATAGA 
GACAGAAAAC AGCAATATTC CATCCAAAGA AGTGCATTTG ATCGCTGTGC TACCTTGTCA 
CAGTCCGGGG GCGCTTTTCC CATTGCTAAT GGCCCCAACC TTACCCTTTT GGTAAGGCAG 
CTTCTGTTTT TTTACAAACA AAATGAAGAC TCAAAACGTT TGATATGGCT GTATCAGAAC 
TTAATTAAAC ACAGCTCTCT GTTTGTCAAG CAGTTGGATG GATCTGAGAG ACTTACATGC 
TTATTTCAGA TAAAAAGATT GATGAGCCTC TGTTGCAGGT TGCTGCAAAA CTGTAATGAT 
GACAGTTTGA ATGTTGCACT TCCAATGAGA ATGCTTGAAG TATTTTCGTC TGAGAATACT 
TACTTGCCTG TTTTACAAGA TGCTAGCTAT GTGGTGTCAG TGATTGAACA AATTTTGCAC 
TACATGATTC ACAATGGGTA TTATAGGTCT CTATATTTGT TGATTAACAG CAAGCTTCCA 
TCAAGTATTG AATATTCTGA TTTATCTCGA GTTCCTATAG CAAAAATTTT GCTAGAGAAT 
GTTCTAAAAC CATTGCACTT TACTTACAAC TCCTGTCCGG AAGGTGCGAG GCAACAAGTT 
TTTACAGCCT TCACAGAGGA GTTTCTGGCA GCACCTTTTA CAGATCAGAT TTTTCATTTC 
ATCATTCCGG CGCTTGCAGA TGCGCAGACC GTTTTCCCTT ACGAGCCCTT TCTGAATGCA 
CTGTTGTTAA TAGAGAGTAG ATGTTCAAGA AAGAGTGGTG GAGCACCCTG GCTTTTCTAT 
TTCGTTTTAA CTGTTGGCGA AAATTATTTG GGGGCCCTCT CTGAGGAAGG GCTGCTGGTG 
TATTTGCGGG TGCTGCAGAC CTTCCTCTCT CAGTTACCAG TCTCTCCTGC CAGCGCGAGC 
TGTCACGACT CAGCCAGTGA CTCTGAGGAG GAGAGTGAAG AAGCCGACAA GCCCTCAAGC 
CCGGAGGATG GCAGACTGTC AGTATCATAC ATAACAGAGG AATGCCTGAA GAAGCTGGAC 
ACAAAGCAGC AGACCAACAC CCTGCTCAAC CTGGTGTGGA GGGACTCTGC GAGCGAGGAG 
GTCTTCACCA CCATGGCCTC CGTCTGCCAC ACGCTGATGG TGCAGCACCG CATGATGGTA 
CCCAAAGTCA GGCTTCTCTA CAGTTTAGCC TTTAATGCCA GGTTTCTGAG ACATCTTTGG 
TTTCTAATAT CTTCCATGTC AACACGGATG ATCACAGGGT CTATGGTACC GTTGCTTCAG 
GTGATATCCA GGGGTTCTCC TATGTCTTTT GAAGATTCTA GTCGAATCAT CCCACTCTTT 
TATCTTTTTA GCTCCTTGTT TAGTCATTCA CTAATTTCCA TACATGATAA CGAATTCTTC 
GGTGATCCCA TAGAAGTTGT AGGTCAAAGA CAATCATCAA TGATGCCTTT TACTTTAGAA 
GAGCTGATAA TGTTGTCTCG ATGCCTTCGA GATGCATGCC TGGGGATCAT CAAGTTGGCT 
TATCCAGAAA CCAAGCCAGA AGTTCGAGAA GAATATATTA CAGCATTTCA GAGTATTGGA 
GTTACTACTA GCTCTGAAAT GCAACAATGC ATACAGATGG AACAGAAAAG ATGGATTCAG 
TTATTTAAGG TTATCACCAA TCTAGTGAAA ATGTTGAAGT CCAGAGACAC GAGGAGAAAT 
TTTTGTCCTC CAAACCACTG GCTGTCAGAA CAAGAAGATA TTAAAGCAGA TAAGGTCACT 
CAGCTCTATG TGCCAGCATC CAGACATGTG TGGAGGTTCC GGCGGATGGG GAGGATAGGC 
CCGCTGCAGT CCACCCTGGA CGTGGGTTTG GAGTCCCCGC CGCTGTCTGT GTCTGAGGAA 
AGACAGCTTG CTGTCCTGAC AGAGTTGCCT TTTGTGGTTC CATTTGAGGA ACGAGTAAAG 
ATCTTTCAGA GGTTGATTTA TGCAGATAAG CAAGAAGTTC AAGGAGATGG TCCATTTCTG 
GATGGAATTA ATGTCACAAT AAGAAGAAAT TACATTTATG AAGATGCTTA TGACAAACTT 
TCTCCAGAAA ATGAGCCTGA TTTGAAAAAG CGGATCCGTG TGCACTTGCT CAATGCCCAT 
GGCCTGGATG AAGCTGGCAT TGATGGTGGT GGTATTTTCA GAGAGTTTTT AAATGAACTA 
CTGAAGTCAG GATTTAACCC CAACCAGGGG TTCTTTAAGA CTACTAATGA AGGGCTTCTG 
TACCCCAACC CGGCTGCTCA GATGCTTGTG GGAGATTCTT TTGCCAGACA TTACTACTTC 
CTAGGCAGAA TGCTTGGAAA GGCTCTCTAT GAGAACATGC TGGTGGAGCT GCCCTTTGCA 
GGCTTCTTTC TTTCCAAGTT GCTTGGAACC AGTGCCGACG TGGACATTCA CCACCTCGCC 
TCCCTAGACC CTGAGGTGTA TAAGAATTTG CTCTTTCTGA AGAGCTACGA AGACGATGTG 
GAGGAGCTTG GGCTGAACTT CACTGTGGTG AACAATGACC TGGGAGAGGC GCAGGTAGTT 
GAACTAAAAT TCGGTGGGAA AGACATCCCT GTCACCAGCG CCAACCGGAT TGCGTACATC 
CACTTGGTGG CAGACTACAG GCTGAACAGG CAGATCCGCC AGCACTGCCT GGCTTTCCGC 
CAGGGCCTTG CCAATGTCGT CAGCCTCGAG TGGCTCCGAA TGTTTGATCA GCAAGAAATT 
CAGGTATTAA TTTCTGGTGC ACAAGTTCCC ATAAGCCTAG AGGACCTAAA ATCCTTTACA 
AACTATTCAG GAGGCTATTC TGCAGACCAT CCTGTTATTA AGGTCTTCTG GAGAGTTGTG 
GAAGGGTTCA CTGATGAAGA AAAGCGCAAA CTGCTGAAGT TTGTAACAAG CTGCTCTCGA 
CCCCCTCTCT TGGGGTTTAA GGAGTTGTAT CCCGCATTTT GTATTCACAA CGGAGGCTCC 
GACCTTGAGC GGCTCCCCAC AGCCAGCACC TGCATGAACC TGCTGAAGCT CCCCGAGTTC 
TATGACGAGA CACTTTTGCG AAGTAAACTT CTCTATGCGA TTGAATGTGC CGCTGGCTTT 
GAGCTGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055486.2
CDS	348..3599
Translation	MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGALSEEGLLVYLRVLQTFLSQLPVSPASASCHDSASDSEEESEEADKPSSPEDGRLSVSYITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS

Target ORF information:

RefSeq Version	NM_014671.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014671.3

ORF Insert Sequence:

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
GAAGAAAGGC GAAGGTTGAA AAATGCAATA ATTATCCAGT CATTTATTCG AGGCTATAGA 
GACAGAAAAC AGCAATATTC CATCCAAAGA AGTGCATTTG ATCGCTGTGC TACCTTGTCA 
CAGTCCGGGG GCGCTTTTCC CATTGCTAAT GGCCCCAACC TTACCCTTTT GGTAAGGCAG 
CTTCTGTTTT TTTACAAACA AAATGAAGAC TCAAAACGTT TGATATGGCT GTATCAGAAC 
TTAATTAAAC ACAGCTCTCT GTTTGTCAAG CAGTTGGATG GATCTGAGAG ACTTACATGC 
TTATTTCAGA TAAAAAGATT GATGAGCCTC TGTTGCAGGT TGCTGCAAAA CTGTAATGAT 
GACAGTTTGA ATGTTGCACT TCCAATGAGA ATGCTTGAAG TATTTTCGTC TGAGAATACT 
TACTTGCCTG TTTTACAAGA TGCTAGCTAT GTGGTGTCAG TGATTGAACA AATTTTGCAC 
TACATGATTC ACAATGGGTA TTATAGGTCT CTATATTTGT TGATTAACAG CAAGCTTCCA 
TCAAGTATTG AATATTCTGA TTTATCTCGA GTTCCTATAG CAAAAATTTT GCTAGAGAAT 
GTTCTAAAAC CATTGCACTT TACTTACAAC TCCTGTCCGG AAGGTGCGAG GCAACAAGTT 
TTTACAGCCT TCACAGAGGA GTTTCTGGCA GCACCTTTTA CAGATCAGAT TTTTCATTTC 
ATCATTCCGG CGCTTGCAGA TGCGCAGACC GTTTTCCCTT ACGAGCCCTT TCTGAATGCA 
CTGTTGTTAA TAGAGAGTAG ATGTTCAAGA AAGAGTGGTG GAGCACCCTG GCTTTTCTAT 
TTCGTTTTAA CTGTTGGCGA AAATTATTTG GGGGCCCTCT CTGAGGAAGG GCTGCTGGTG 
TATTTGCGGG TGCTGCAGAC CTTCCTCTCT CAGTTACCAG TCTCTCCTGC CAGCGCGAGC 
TGTCACGACT CAGCCAGTGA CTCTGAGGAG GAGAGTGAAG AAGCCGACAA GCCCTCAAGC 
CCGGAGGATG GCAGACTGTC AGTATCATAC ATAACAGAGG AATGCCTGAA GAAGCTGGAC 
ACAAAGCAGC AGACCAACAC CCTGCTCAAC CTGGTGTGGA GGGACTCTGC GAGCGAGGAG 
GTCTTCACCA CCATGGCCTC CGTCTGCCAC ACGCTGATGG TGCAGCACCG CATGATGGTA 
CCCAAAGTCA GGCTTCTCTA CAGTTTAGCC TTTAATGCCA GGTTTCTGAG ACATCTTTGG 
TTTCTAATAT CTTCCATGTC AACACGGATG ATCACAGGGT CTATGGTACC GTTGCTTCAG 
GTGATATCCA GGGGTTCTCC TATGTCTTTT GAAGATTCTA GTCGAATCAT CCCACTCTTT 
TATCTTTTTA GCTCCTTGTT TAGTCATTCA CTAATTTCCA TACATGATAA CGAATTCTTC 
GGTGATCCCA TAGAAGTTGT AGGTCAAAGA CAATCATCAA TGATGCCTTT TACTTTAGAA 
GAGCTGATAA TGTTGTCTCG ATGCCTTCGA GATGCATGCC TGGGGATCAT CAAGTTGGCT 
TATCCAGAAA CCAAGCCAGA AGTTCGAGAA GAATATATTA CAGCATTTCA GAGTATTGGA 
GTTACTACTA GCTCTGAAAT GCAACAATGC ATACAGATGG AACAGAAAAG ATGGATTCAG 
TTATTTAAGG TTATCACCAA TCTAGTGAAA ATGTTGAAGT CCAGAGACAC GAGGAGAAAT 
TTTTGTCCTC CAAACCACTG GCTGTCAGAA CAAGAAGATA TTAAAGCAGA TAAGGTCACT 
CAGCTCTATG TGCCAGCATC CAGACATGTG TGGAGGTTCC GGCGGATGGG GAGGATAGGC 
CCGCTGCAGT CCACCCTGGA CGTGGGTTTG GAGTCCCCGC CGCTGTCTGT GTCTGAGGAA 
AGACAGCTTG CTGTCCTGAC AGAGTTGCCT TTTGTGGTTC CATTTGAGGA ACGAGTAAAG 
ATCTTTCAGA GGTTGATTTA TGCAGATAAG CAAGAAGTTC AAGGAGATGG TCCATTTCTG 
GATGGAATTA ATGTCACAAT AAGAAGAAAT TACATTTATG AAGATGCTTA TGACAAACTT 
TCTCCAGAAA ATGAGCCTGA TTTGAAAAAG CGGATCCGTG TGCACTTGCT CAATGCCCAT 
GGCCTGGATG AAGCTGGCAT TGATGGTGGT GGTATTTTCA GAGAGTTTTT AAATGAACTA 
CTGAAGTCAG GATTTAACCC CAACCAGGGG TTCTTTAAGA CTACTAATGA AGGGCTTCTG 
TACCCCAACC CGGCTGCTCA GATGCTTGTG GGAGATTCTT TTGCCAGACA TTACTACTTC 
CTAGGCAGAA TGCTTGGAAA GGCTCTCTAT GAGAACATGC TGGTGGAGCT GCCCTTTGCA 
GGCTTCTTTC TTTCCAAGTT GCTTGGAACC AGTGCCGACG TGGACATTCA CCACCTCGCC 
TCCCTAGACC CTGAGGTGTA TAAGAATTTG CTCTTTCTGA AGAGCTACGA AGACGATGTG 
GAGGAGCTTG GGCTGAACTT CACTGTGGTG AACAATGACC TGGGAGAGGC GCAGGTAGTT 
GAACTAAAAT TCGGTGGGAA AGACATCCCT GTCACCAGCG CCAACCGGAT TGCGTACATC 
CACTTGGTGG CAGACTACAG GCTGAACAGG CAGATCCGCC AGCACTGCCT GGCTTTCCGC 
CAGGGCCTTG CCAATGTCGT CAGCCTCGAG TGGCTCCGAA TGTTTGATCA GCAAGAAATT 
CAGGTATTAA TTTCTGGTGC ACAAGTTCCC ATAAGCCTAG AGGACCTAAA ATCCTTTACA 
AACTATTCAG GAGGCTATTC TGCAGACCAT CCTGTTATTA AGGTCTTCTG GAGAGTTGTG 
GAAGGGTTCA CTGATGAAGA AAAGCGCAAA CTGCTGAAGT TTGTAACAAG CTGCTCTCGA 
CCCCCTCTCT TGGGGTTTAA GGAGTTGTAT CCCGCATTTT GTATTCACAA CGGAGGCTCC 
GACCTTGAGC GGCTCCCCAC AGCCAGCACC TGCATGAACC TGCTGAAGCT CCCCGAGTTC 
TATGACGAGA CACTTTTGCG AAGTAAACTT CTCTATGCGA TTGAATGTGC CGCTGGCTTT 
GAGCTGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBE3C ( NM_014671.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_055486.2 Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.

Price & Availability↑

CloneID	OHu09188
Clone ID Related Accession (Same CDS sequence)	NM_014671.3 , NM_014671.2
Accession Version	NM_014671.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3252bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-17
Organism	Homo sapiens(human)
Product	ubiquitin-protein ligase E3C
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DB454915.1, D13635.1, DB085748.1, AK127280.1, AA596042.1 and CD366848.1. On May 13, 2008 this sequence version replaced NM_014671.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: D13635.1, SRR1660805.199761.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
GAAGAAAGGC GAAGGTTGAA AAATGCAATA ATTATCCAGT CATTTATTCG AGGCTATAGA 
GACAGAAAAC AGCAATATTC CATCCAAAGA AGTGCATTTG ATCGCTGTGC TACCTTGTCA 
CAGTCCGGGG GCGCTTTTCC CATTGCTAAT GGCCCCAACC TTACCCTTTT GGTAAGGCAG 
CTTCTGTTTT TTTACAAACA AAATGAAGAC TCAAAACGTT TGATATGGCT GTATCAGAAC 
TTAATTAAAC ACAGCTCTCT GTTTGTCAAG CAGTTGGATG GATCTGAGAG ACTTACATGC 
TTATTTCAGA TAAAAAGATT GATGAGCCTC TGTTGCAGGT TGCTGCAAAA CTGTAATGAT 
GACAGTTTGA ATGTTGCACT TCCAATGAGA ATGCTTGAAG TATTTTCGTC TGAGAATACT 
TACTTGCCTG TTTTACAAGA TGCTAGCTAT GTGGTGTCAG TGATTGAACA AATTTTGCAC 
TACATGATTC ACAATGGGTA TTATAGGTCT CTATATTTGT TGATTAACAG CAAGCTTCCA 
TCAAGTATTG AATATTCTGA TTTATCTCGA GTTCCTATAG CAAAAATTTT GCTAGAGAAT 
GTTCTAAAAC CATTGCACTT TACTTACAAC TCCTGTCCGG AAGGTGCGAG GCAACAAGTT 
TTTACAGCCT TCACAGAGGA GTTTCTGGCA GCACCTTTTA CAGATCAGAT TTTTCATTTC 
ATCATTCCGG CGCTTGCAGA TGCGCAGACC GTTTTCCCTT ACGAGCCCTT TCTGAATGCA 
CTGTTGTTAA TAGAGAGTAG ATGTTCAAGA AAGAGTGGTG GAGCACCCTG GCTTTTCTAT 
TTCGTTTTAA CTGTTGGCGA AAATTATTTG GGGGCCCTCT CTGAGGAAGG GCTGCTGGTG 
TATTTGCGGG TGCTGCAGAC CTTCCTCTCT CAGTTACCAG TCTCTCCTGC CAGCGCGAGC 
TGTCACGACT CAGCCAGTGA CTCTGAGGAG GAGAGTGAAG AAGCCGACAA GCCCTCAAGC 
CCGGAGGATG GCAGACTGTC AGTATCATAC ATAACAGAGG AATGCCTGAA GAAGCTGGAC 
ACAAAGCAGC AGACCAACAC CCTGCTCAAC CTGGTGTGGA GGGACTCTGC GAGCGAGGAG 
GTCTTCACCA CCATGGCCTC CGTCTGCCAC ACGCTGATGG TGCAGCACCG CATGATGGTA 
CCCAAAGTCA GGCTTCTCTA CAGTTTAGCC TTTAATGCCA GGTTTCTGAG ACATCTTTGG 
TTTCTAATAT CTTCCATGTC AACACGGATG ATCACAGGGT CTATGGTACC GTTGCTTCAG 
GTGATATCCA GGGGTTCTCC TATGTCTTTT GAAGATTCTA GTCGAATCAT CCCACTCTTT 
TATCTTTTTA GCTCCTTGTT TAGTCATTCA CTAATTTCCA TACATGATAA CGAATTCTTC 
GGTGATCCCA TAGAAGTTGT AGGTCAAAGA CAATCATCAA TGATGCCTTT TACTTTAGAA 
GAGCTGATAA TGTTGTCTCG ATGCCTTCGA GATGCATGCC TGGGGATCAT CAAGTTGGCT 
TATCCAGAAA CCAAGCCAGA AGTTCGAGAA GAATATATTA CAGCATTTCA GAGTATTGGA 
GTTACTACTA GCTCTGAAAT GCAACAATGC ATACAGATGG AACAGAAAAG ATGGATTCAG 
TTATTTAAGG TTATCACCAA TCTAGTGAAA ATGTTGAAGT CCAGAGACAC GAGGAGAAAT 
TTTTGTCCTC CAAACCACTG GCTGTCAGAA CAAGAAGATA TTAAAGCAGA TAAGGTCACT 
CAGCTCTATG TGCCAGCATC CAGACATGTG TGGAGGTTCC GGCGGATGGG GAGGATAGGC 
CCGCTGCAGT CCACCCTGGA CGTGGGTTTG GAGTCCCCGC CGCTGTCTGT GTCTGAGGAA 
AGACAGCTTG CTGTCCTGAC AGAGTTGCCT TTTGTGGTTC CATTTGAGGA ACGAGTAAAG 
ATCTTTCAGA GGTTGATTTA TGCAGATAAG CAAGAAGTTC AAGGAGATGG TCCATTTCTG 
GATGGAATTA ATGTCACAAT AAGAAGAAAT TACATTTATG AAGATGCTTA TGACAAACTT 
TCTCCAGAAA ATGAGCCTGA TTTGAAAAAG CGGATCCGTG TGCACTTGCT CAATGCCCAT 
GGCCTGGATG AAGCTGGCAT TGATGGTGGT GGTATTTTCA GAGAGTTTTT AAATGAACTA 
CTGAAGTCAG GATTTAACCC CAACCAGGGG TTCTTTAAGA CTACTAATGA AGGGCTTCTG 
TACCCCAACC CGGCTGCTCA GATGCTTGTG GGAGATTCTT TTGCCAGACA TTACTACTTC 
CTAGGCAGAA TGCTTGGAAA GGCTCTCTAT GAGAACATGC TGGTGGAGCT GCCCTTTGCA 
GGCTTCTTTC TTTCCAAGTT GCTTGGAACC AGTGCCGACG TGGACATTCA CCACCTCGCC 
TCCCTAGACC CTGAGGTGTA TAAGAATTTG CTCTTTCTGA AGAGCTACGA AGACGATGTG 
GAGGAGCTTG GGCTGAACTT CACTGTGGTG AACAATGACC TGGGAGAGGC GCAGGTAGTT 
GAACTAAAAT TCGGTGGGAA AGACATCCCT GTCACCAGCG CCAACCGGAT TGCGTACATC 
CACTTGGTGG CAGACTACAG GCTGAACAGG CAGATCCGCC AGCACTGCCT GGCTTTCCGC 
CAGGGCCTTG CCAATGTCGT CAGCCTCGAG TGGCTCCGAA TGTTTGATCA GCAAGAAATT 
CAGGTATTAA TTTCTGGTGC ACAAGTTCCC ATAAGCCTAG AGGACCTAAA ATCCTTTACA 
AACTATTCAG GAGGCTATTC TGCAGACCAT CCTGTTATTA AGGTCTTCTG GAGAGTTGTG 
GAAGGGTTCA CTGATGAAGA AAAGCGCAAA CTGCTGAAGT TTGTAACAAG CTGCTCTCGA 
CCCCCTCTCT TGGGGTTTAA GGAGTTGTAT CCCGCATTTT GTATTCACAA CGGAGGCTCC 
GACCTTGAGC GGCTCCCCAC AGCCAGCACC TGCATGAACC TGCTGAAGCT CCCCGAGTTC 
TATGACGAGA CACTTTTGCG AAGTAAACTT CTCTATGCGA TTGAATGTGC CGCTGGCTTT 
GAGCTGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_055486.2
CDS	313..3564
Translation	MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGALSEEGLLVYLRVLQTFLSQLPVSPASASCHDSASDSEEESEEADKPSSPEDGRLSVSYITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS

Target ORF information:

RefSeq Version	NM_014671.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin protein ligase E3C (UBE3C), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_014671.2

ORF Insert Sequence:

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
GAAGAAAGGC GAAGGTTGAA AAATGCAATA ATTATCCAGT CATTTATTCG AGGCTATAGA 
GACAGAAAAC AGCAATATTC CATCCAAAGA AGTGCATTTG ATCGCTGTGC TACCTTGTCA 
CAGTCCGGGG GCGCTTTTCC CATTGCTAAT GGCCCCAACC TTACCCTTTT GGTAAGGCAG 
CTTCTGTTTT TTTACAAACA AAATGAAGAC TCAAAACGTT TGATATGGCT GTATCAGAAC 
TTAATTAAAC ACAGCTCTCT GTTTGTCAAG CAGTTGGATG GATCTGAGAG ACTTACATGC 
TTATTTCAGA TAAAAAGATT GATGAGCCTC TGTTGCAGGT TGCTGCAAAA CTGTAATGAT 
GACAGTTTGA ATGTTGCACT TCCAATGAGA ATGCTTGAAG TATTTTCGTC TGAGAATACT 
TACTTGCCTG TTTTACAAGA TGCTAGCTAT GTGGTGTCAG TGATTGAACA AATTTTGCAC 
TACATGATTC ACAATGGGTA TTATAGGTCT CTATATTTGT TGATTAACAG CAAGCTTCCA 
TCAAGTATTG AATATTCTGA TTTATCTCGA GTTCCTATAG CAAAAATTTT GCTAGAGAAT 
GTTCTAAAAC CATTGCACTT TACTTACAAC TCCTGTCCGG AAGGTGCGAG GCAACAAGTT 
TTTACAGCCT TCACAGAGGA GTTTCTGGCA GCACCTTTTA CAGATCAGAT TTTTCATTTC 
ATCATTCCGG CGCTTGCAGA TGCGCAGACC GTTTTCCCTT ACGAGCCCTT TCTGAATGCA 
CTGTTGTTAA TAGAGAGTAG ATGTTCAAGA AAGAGTGGTG GAGCACCCTG GCTTTTCTAT 
TTCGTTTTAA CTGTTGGCGA AAATTATTTG GGGGCCCTCT CTGAGGAAGG GCTGCTGGTG 
TATTTGCGGG TGCTGCAGAC CTTCCTCTCT CAGTTACCAG TCTCTCCTGC CAGCGCGAGC 
TGTCACGACT CAGCCAGTGA CTCTGAGGAG GAGAGTGAAG AAGCCGACAA GCCCTCAAGC 
CCGGAGGATG GCAGACTGTC AGTATCATAC ATAACAGAGG AATGCCTGAA GAAGCTGGAC 
ACAAAGCAGC AGACCAACAC CCTGCTCAAC CTGGTGTGGA GGGACTCTGC GAGCGAGGAG 
GTCTTCACCA CCATGGCCTC CGTCTGCCAC ACGCTGATGG TGCAGCACCG CATGATGGTA 
CCCAAAGTCA GGCTTCTCTA CAGTTTAGCC TTTAATGCCA GGTTTCTGAG ACATCTTTGG 
TTTCTAATAT CTTCCATGTC AACACGGATG ATCACAGGGT CTATGGTACC GTTGCTTCAG 
GTGATATCCA GGGGTTCTCC TATGTCTTTT GAAGATTCTA GTCGAATCAT CCCACTCTTT 
TATCTTTTTA GCTCCTTGTT TAGTCATTCA CTAATTTCCA TACATGATAA CGAATTCTTC 
GGTGATCCCA TAGAAGTTGT AGGTCAAAGA CAATCATCAA TGATGCCTTT TACTTTAGAA 
GAGCTGATAA TGTTGTCTCG ATGCCTTCGA GATGCATGCC TGGGGATCAT CAAGTTGGCT 
TATCCAGAAA CCAAGCCAGA AGTTCGAGAA GAATATATTA CAGCATTTCA GAGTATTGGA 
GTTACTACTA GCTCTGAAAT GCAACAATGC ATACAGATGG AACAGAAAAG ATGGATTCAG 
TTATTTAAGG TTATCACCAA TCTAGTGAAA ATGTTGAAGT CCAGAGACAC GAGGAGAAAT 
TTTTGTCCTC CAAACCACTG GCTGTCAGAA CAAGAAGATA TTAAAGCAGA TAAGGTCACT 
CAGCTCTATG TGCCAGCATC CAGACATGTG TGGAGGTTCC GGCGGATGGG GAGGATAGGC 
CCGCTGCAGT CCACCCTGGA CGTGGGTTTG GAGTCCCCGC CGCTGTCTGT GTCTGAGGAA 
AGACAGCTTG CTGTCCTGAC AGAGTTGCCT TTTGTGGTTC CATTTGAGGA ACGAGTAAAG 
ATCTTTCAGA GGTTGATTTA TGCAGATAAG CAAGAAGTTC AAGGAGATGG TCCATTTCTG 
GATGGAATTA ATGTCACAAT AAGAAGAAAT TACATTTATG AAGATGCTTA TGACAAACTT 
TCTCCAGAAA ATGAGCCTGA TTTGAAAAAG CGGATCCGTG TGCACTTGCT CAATGCCCAT 
GGCCTGGATG AAGCTGGCAT TGATGGTGGT GGTATTTTCA GAGAGTTTTT AAATGAACTA 
CTGAAGTCAG GATTTAACCC CAACCAGGGG TTCTTTAAGA CTACTAATGA AGGGCTTCTG 
TACCCCAACC CGGCTGCTCA GATGCTTGTG GGAGATTCTT TTGCCAGACA TTACTACTTC 
CTAGGCAGAA TGCTTGGAAA GGCTCTCTAT GAGAACATGC TGGTGGAGCT GCCCTTTGCA 
GGCTTCTTTC TTTCCAAGTT GCTTGGAACC AGTGCCGACG TGGACATTCA CCACCTCGCC 
TCCCTAGACC CTGAGGTGTA TAAGAATTTG CTCTTTCTGA AGAGCTACGA AGACGATGTG 
GAGGAGCTTG GGCTGAACTT CACTGTGGTG AACAATGACC TGGGAGAGGC GCAGGTAGTT 
GAACTAAAAT TCGGTGGGAA AGACATCCCT GTCACCAGCG CCAACCGGAT TGCGTACATC 
CACTTGGTGG CAGACTACAG GCTGAACAGG CAGATCCGCC AGCACTGCCT GGCTTTCCGC 
CAGGGCCTTG CCAATGTCGT CAGCCTCGAG TGGCTCCGAA TGTTTGATCA GCAAGAAATT 
CAGGTATTAA TTTCTGGTGC ACAAGTTCCC ATAAGCCTAG AGGACCTAAA ATCCTTTACA 
AACTATTCAG GAGGCTATTC TGCAGACCAT CCTGTTATTA AGGTCTTCTG GAGAGTTGTG 
GAAGGGTTCA CTGATGAAGA AAAGCGCAAA CTGCTGAAGT TTGTAACAAG CTGCTCTCGA 
CCCCCTCTCT TGGGGTTTAA GGAGTTGTAT CCCGCATTTT GTATTCACAA CGGAGGCTCC 
GACCTTGAGC GGCTCCCCAC AGCCAGCACC TGCATGAACC TGCTGAAGCT CCCCGAGTTC 
TATGACGAGA CACTTTTGCG AAGTAAACTT CTCTATGCGA TTGAATGTGC CGCTGGCTTT 
GAGCTGAGCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBE3C ( XM_005249564.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005249621.1 Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu41879
Clone ID Related Accession (Same CDS sequence)	XM_005249564.4
Accession Version	XM_005249564.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3177bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin-protein ligase E3C isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005249564.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
TATTCCATCC AAAGAAGTGC ATTTGATCGC TGTGCTACCT TGTCACAGTC CGGGGGCGCT 
TTTCCCATTG CTAATGGCCC CAACCTTACC CTTTTGGTAA GGCAGCTTCT GTTTTTTTAC 
AAACAAAATG AAGACTCAAA ACGTTTGATA TGGCTGTATC AGAACTTAAT TAAACACAGC 
TCTCTGTTTG TCAAGCAGTT GGATGGATCT GAGAGACTTA CATGCTTATT TCAGATAAAA 
AGATTGATGA GCCTCTGTTG CAGGTTGCTG CAAAACTGTA ATGATGACAG TTTGAATGTT 
GCACTTCCAA TGAGAATGCT TGAAGTATTT TCGTCTGAGA ATACTTACTT GCCTGTTTTA 
CAAGATGCTA GCTATGTGGT GTCAGTGATT GAACAAATTT TGCACTACAT GATTCACAAT 
GGGTATTATA GGTCTCTATA TTTGTTGATT AACAGCAAGC TTCCATCAAG TATTGAATAT 
TCTGATTTAT CTCGAGTTCC TATAGCAAAA ATTTTGCTAG AGAATGTTCT AAAACCATTG 
CACTTTACTT ACAACTCCTG TCCGGAAGGT GCGAGGCAAC AAGTTTTTAC AGCCTTCACA 
GAGGAGTTTC TGGCAGCACC TTTTACAGAT CAGATTTTTC ATTTCATCAT TCCGGCGCTT 
GCAGATGCGC AGACCGTTTT CCCTTACGAG CCCTTTCTGA ATGCACTGTT GTTAATAGAG 
AGTAGATGTT CAAGAAAGAG TGGTGGAGCA CCCTGGCTTT TCTATTTCGT TTTAACTGTT 
GGCGAAAATT ATTTGGGGGC CCTCTCTGAG GAAGGGCTGC TGGTGTATTT GCGGGTGCTG 
CAGACCTTCC TCTCTCAGTT ACCAGTCTCT CCTGCCAGCG CGAGCTGTCA CGACTCAGCC 
AGTGACTCTG AGGAGGAGAG TGAAGAAGCC GACAAGCCCT CAAGCCCGGA GGATGGCAGA 
CTGTCAGTAT CATACATAAC AGAGGAATGC CTGAAGAAGC TGGACACAAA GCAGCAGACC 
AACACCCTGC TCAACCTGGT GTGGAGGGAC TCTGCGAGCG AGGAGGTCTT CACCACCATG 
GCCTCCGTCT GCCACACGCT GATGGTGCAG CACCGCATGA TGGTACCCAA AGTCAGGCTT 
CTCTACAGTT TAGCCTTTAA TGCCAGGTTT CTGAGACATC TTTGGTTTCT AATATCTTCC 
ATGTCAACAC GGATGATCAC AGGGTCTATG GTACCGTTGC TTCAGGTGAT ATCCAGGGGT 
TCTCCTATGT CTTTTGAAGA TTCTAGTCGA ATCATCCCAC TCTTTTATCT TTTTAGCTCC 
TTGTTTAGTC ATTCACTAAT TTCCATACAT GATAACGAAT TCTTCGGTGA TCCCATAGAA 
GTTGTAGGTC AAAGACAATC ATCAATGATG CCTTTTACTT TAGAAGAGCT GATAATGTTG 
TCTCGATGCC TTCGAGATGC ATGCCTGGGG ATCATCAAGT TGGCTTATCC AGAAACCAAG 
CCAGAAGTTC GAGAAGAATA TATTACAGCA TTTCAGAGTA TTGGAGTTAC TACTAGCTCT 
GAAATGCAAC AATGCATACA GATGGAACAG AAAAGATGGA TTCAGTTATT TAAGGTTATC 
ACCAATCTAG TGAAAATGTT GAAGTCCAGA GACACGAGGA GAAATTTTTG TCCTCCAAAC 
CACTGGCTGT CAGAACAAGA AGATATTAAA GCAGATAAGG TCACTCAGCT CTATGTGCCA 
GCATCCAGAC ATGTGTGGAG GTTCCGGCGG ATGGGGAGGA TAGGCCCGCT GCAGTCCACC 
CTGGACGTGG GTTTGGAGTC CCCGCCGCTG TCTGTGTCTG AGGAAAGACA GCTTGCTGTC 
CTGACAGAGT TGCCTTTTGT GGTTCCATTT GAGGAACGAG TAAAGATCTT TCAGAGGTTG 
ATTTATGCAG ATAAGCAAGA AGTTCAAGGA GATGGTCCAT TTCTGGATGG AATTAATGTC 
ACAATAAGAA GAAATTACAT TTATGAAGAT GCTTATGACA AACTTTCTCC AGAAAATGAG 
CCTGATTTGA AAAAGCGGAT CCGTGTGCAC TTGCTCAATG CCCATGGCCT GGATGAAGCT 
GGCATTGATG GTGGTGGTAT TTTCAGAGAG TTTTTAAATG AACTACTGAA GTCAGGATTT 
AACCCCAACC AGGGGTTCTT TAAGACTACT AATGAAGGGC TTCTGTACCC CAACCCGGCT 
GCTCAGATGC TTGTGGGAGA TTCTTTTGCC AGACATTACT ACTTCCTAGG CAGAATGCTT 
GGAAAGGCTC TCTATGAGAA CATGCTGGTG GAGCTGCCCT TTGCAGGCTT CTTTCTTTCC 
AAGTTGCTTG GAACCAGTGC CGACGTGGAC ATTCACCACC TCGCCTCCCT AGACCCTGAG 
GTGTATAAGA ATTTGCTCTT TCTGAAGAGC TACGAAGACG ATGTGGAGGA GCTTGGGCTG 
AACTTCACTG TGGTGAACAA TGACCTGGGA GAGGCGCAGG TAGTTGAACT AAAATTCGGT 
GGGAAAGACA TCCCTGTCAC CAGCGCCAAC CGGATTGCGT ACATCCACTT GGTGGCAGAC 
TACAGGCTGA ACAGGCAGAT CCGCCAGCAC TGCCTGGCTT TCCGCCAGGG CCTTGCCAAT 
GTCGTCAGCC TCGAGTGGCT CCGAATGTTT GATCAGCAAG AAATTCAGGT ATTAATTTCT 
GGTGCACAAG TTCCCATAAG CCTAGAGGAC CTAAAATCCT TTACAAACTA TTCAGGAGGC 
TATTCTGCAG ACCATCCTGT TATTAAGGTC TTCTGGAGAG TTGTGGAAGG GTTCACTGAT 
GAAGAAAAGC GCAAACTGCT GAAGTTTGTA ACAAGCTGCT CTCGACCCCC TCTCTTGGGG 
TTTAAGGAGT TGTATCCCGC ATTTTGTATT CACAACGGAG GCTCCGACCT TGAGCGGCTC 
CCCACAGCCA GCACCTGCAT GAACCTGCTG AAGCTCCCCG AGTTCTATGA CGAGACACTT 
TTGCGAAGTA AACTTCTCTA TGCGATTGAA TGTGCCGCTG GCTTTGAGCT GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005249621.1
CDS	322..3498
Translation	MFSFEGDFKTRPKVSLGGASRKEEKASLLHRTQEERRKREYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGALSEEGLLVYLRVLQTFLSQLPVSPASASCHDSASDSEEESEEADKPSSPEDGRLSVSYITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS

Target ORF information:

RefSeq Version	XM_005249564.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005249564.4

ORF Insert Sequence:

ATGTTCAGCT TCGAAGGCGA CTTCAAGACG CGGCCCAAGG TGTCCCTTGG CGGCGCGAGC 
AGGAAGGAGG AAAAGGCTTC TCTTTTACAT CGTACTCAGG AAGAAAGAAG AAAGAGAGAG 
TATTCCATCC AAAGAAGTGC ATTTGATCGC TGTGCTACCT TGTCACAGTC CGGGGGCGCT 
TTTCCCATTG CTAATGGCCC CAACCTTACC CTTTTGGTAA GGCAGCTTCT GTTTTTTTAC 
AAACAAAATG AAGACTCAAA ACGTTTGATA TGGCTGTATC AGAACTTAAT TAAACACAGC 
TCTCTGTTTG TCAAGCAGTT GGATGGATCT GAGAGACTTA CATGCTTATT TCAGATAAAA 
AGATTGATGA GCCTCTGTTG CAGGTTGCTG CAAAACTGTA ATGATGACAG TTTGAATGTT 
GCACTTCCAA TGAGAATGCT TGAAGTATTT TCGTCTGAGA ATACTTACTT GCCTGTTTTA 
CAAGATGCTA GCTATGTGGT GTCAGTGATT GAACAAATTT TGCACTACAT GATTCACAAT 
GGGTATTATA GGTCTCTATA TTTGTTGATT AACAGCAAGC TTCCATCAAG TATTGAATAT 
TCTGATTTAT CTCGAGTTCC TATAGCAAAA ATTTTGCTAG AGAATGTTCT AAAACCATTG 
CACTTTACTT ACAACTCCTG TCCGGAAGGT GCGAGGCAAC AAGTTTTTAC AGCCTTCACA 
GAGGAGTTTC TGGCAGCACC TTTTACAGAT CAGATTTTTC ATTTCATCAT TCCGGCGCTT 
GCAGATGCGC AGACCGTTTT CCCTTACGAG CCCTTTCTGA ATGCACTGTT GTTAATAGAG 
AGTAGATGTT CAAGAAAGAG TGGTGGAGCA CCCTGGCTTT TCTATTTCGT TTTAACTGTT 
GGCGAAAATT ATTTGGGGGC CCTCTCTGAG GAAGGGCTGC TGGTGTATTT GCGGGTGCTG 
CAGACCTTCC TCTCTCAGTT ACCAGTCTCT CCTGCCAGCG CGAGCTGTCA CGACTCAGCC 
AGTGACTCTG AGGAGGAGAG TGAAGAAGCC GACAAGCCCT CAAGCCCGGA GGATGGCAGA 
CTGTCAGTAT CATACATAAC AGAGGAATGC CTGAAGAAGC TGGACACAAA GCAGCAGACC 
AACACCCTGC TCAACCTGGT GTGGAGGGAC TCTGCGAGCG AGGAGGTCTT CACCACCATG 
GCCTCCGTCT GCCACACGCT GATGGTGCAG CACCGCATGA TGGTACCCAA AGTCAGGCTT 
CTCTACAGTT TAGCCTTTAA TGCCAGGTTT CTGAGACATC TTTGGTTTCT AATATCTTCC 
ATGTCAACAC GGATGATCAC AGGGTCTATG GTACCGTTGC TTCAGGTGAT ATCCAGGGGT 
TCTCCTATGT CTTTTGAAGA TTCTAGTCGA ATCATCCCAC TCTTTTATCT TTTTAGCTCC 
TTGTTTAGTC ATTCACTAAT TTCCATACAT GATAACGAAT TCTTCGGTGA TCCCATAGAA 
GTTGTAGGTC AAAGACAATC ATCAATGATG CCTTTTACTT TAGAAGAGCT GATAATGTTG 
TCTCGATGCC TTCGAGATGC ATGCCTGGGG ATCATCAAGT TGGCTTATCC AGAAACCAAG 
CCAGAAGTTC GAGAAGAATA TATTACAGCA TTTCAGAGTA TTGGAGTTAC TACTAGCTCT 
GAAATGCAAC AATGCATACA GATGGAACAG AAAAGATGGA TTCAGTTATT TAAGGTTATC 
ACCAATCTAG TGAAAATGTT GAAGTCCAGA GACACGAGGA GAAATTTTTG TCCTCCAAAC 
CACTGGCTGT CAGAACAAGA AGATATTAAA GCAGATAAGG TCACTCAGCT CTATGTGCCA 
GCATCCAGAC ATGTGTGGAG GTTCCGGCGG ATGGGGAGGA TAGGCCCGCT GCAGTCCACC 
CTGGACGTGG GTTTGGAGTC CCCGCCGCTG TCTGTGTCTG AGGAAAGACA GCTTGCTGTC 
CTGACAGAGT TGCCTTTTGT GGTTCCATTT GAGGAACGAG TAAAGATCTT TCAGAGGTTG 
ATTTATGCAG ATAAGCAAGA AGTTCAAGGA GATGGTCCAT TTCTGGATGG AATTAATGTC 
ACAATAAGAA GAAATTACAT TTATGAAGAT GCTTATGACA AACTTTCTCC AGAAAATGAG 
CCTGATTTGA AAAAGCGGAT CCGTGTGCAC TTGCTCAATG CCCATGGCCT GGATGAAGCT 
GGCATTGATG GTGGTGGTAT TTTCAGAGAG TTTTTAAATG AACTACTGAA GTCAGGATTT 
AACCCCAACC AGGGGTTCTT TAAGACTACT AATGAAGGGC TTCTGTACCC CAACCCGGCT 
GCTCAGATGC TTGTGGGAGA TTCTTTTGCC AGACATTACT ACTTCCTAGG CAGAATGCTT 
GGAAAGGCTC TCTATGAGAA CATGCTGGTG GAGCTGCCCT TTGCAGGCTT CTTTCTTTCC 
AAGTTGCTTG GAACCAGTGC CGACGTGGAC ATTCACCACC TCGCCTCCCT AGACCCTGAG 
GTGTATAAGA ATTTGCTCTT TCTGAAGAGC TACGAAGACG ATGTGGAGGA GCTTGGGCTG 
AACTTCACTG TGGTGAACAA TGACCTGGGA GAGGCGCAGG TAGTTGAACT AAAATTCGGT 
GGGAAAGACA TCCCTGTCAC CAGCGCCAAC CGGATTGCGT ACATCCACTT GGTGGCAGAC 
TACAGGCTGA ACAGGCAGAT CCGCCAGCAC TGCCTGGCTT TCCGCCAGGG CCTTGCCAAT 
GTCGTCAGCC TCGAGTGGCT CCGAATGTTT GATCAGCAAG AAATTCAGGT ATTAATTTCT 
GGTGCACAAG TTCCCATAAG CCTAGAGGAC CTAAAATCCT TTACAAACTA TTCAGGAGGC 
TATTCTGCAG ACCATCCTGT TATTAAGGTC TTCTGGAGAG TTGTGGAAGG GTTCACTGAT 
GAAGAAAAGC GCAAACTGCT GAAGTTTGTA ACAAGCTGCT CTCGACCCCC TCTCTTGGGG 
TTTAAGGAGT TGTATCCCGC ATTTTGTATT CACAACGGAG GCTCCGACCT TGAGCGGCTC 
CCCACAGCCA GCACCTGCAT GAACCTGCTG AAGCTCCCCG AGTTCTATGA CGAGACACTT 
TTGCGAAGTA AACTTCTCTA TGCGATTGAA TGTGCCGCTG GCTTTGAGCT GAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBE3C ( XM_017012818.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868307.1 Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu63161
Clone ID Related Accession (Same CDS sequence)	XM_017012818.1
Accession Version	XM_017012818.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3189bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	ubiquitin-protein ligase E3C isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGGAAA AGGCTTCTCT TTTACATCGT ACTCAGGAAG AAAGAAGAAA GAGAGAGGAA 
GAAAGGCGAA GGTTGAAAAA TGCAATAATT ATCCAGTCAT TTATTCGAGG CTATAGAGAC 
AGAAAACAGC AATATTCCAT CCAAAGAAGT GCATTTGATC GCTGTGCTAC CTTGTCACAG 
TCCGGGGGCG CTTTTCCCAT TGCTAATGGC CCCAACCTTA CCCTTTTGGT AAGGCAGCTT 
CTGTTTTTTT ACAAACAAAA TGAAGACTCA AAACGTTTGA TATGGCTGTA TCAGAACTTA 
ATTAAACACA GCTCTCTGTT TGTCAAGCAG TTGGATGGAT CTGAGAGACT TACATGCTTA 
TTTCAGATAA AAAGATTGAT GAGCCTCTGT TGCAGGTTGC TGCAAAACTG TAATGATGAC 
AGTTTGAATG TTGCACTTCC AATGAGAATG CTTGAAGTAT TTTCGTCTGA GAATACTTAC 
TTGCCTGTTT TACAAGATGC TAGCTATGTG GTGTCAGTGA TTGAACAAAT TTTGCACTAC 
ATGATTCACA ATGGGTATTA TAGGTCTCTA TATTTGTTGA TTAACAGCAA GCTTCCATCA 
AGTATTGAAT ATTCTGATTT ATCTCGAGTT CCTATAGCAA AAATTTTGCT AGAGAATGTT 
CTAAAACCAT TGCACTTTAC TTACAACTCC TGTCCGGAAG GTGCGAGGCA ACAAGTTTTT 
ACAGCCTTCA CAGAGGAGTT TCTGGCAGCA CCTTTTACAG ATCAGATTTT TCATTTCATC 
ATTCCGGCGC TTGCAGATGC GCAGACCGTT TTCCCTTACG AGCCCTTTCT GAATGCACTG 
TTGTTAATAG AGAGTAGATG TTCAAGAAAG AGTGGTGGAG CACCCTGGCT TTTCTATTTC 
GTTTTAACTG TTGGCGAAAA TTATTTGGGG GCCCTCTCTG AGGAAGGGCT GCTGGTGTAT 
TTGCGGGTGC TGCAGACCTT CCTCTCTCAG TTACCAGTCT CTCCTGCCAG CGCGAGCTGT 
CACGACTCAG CCAGTGACTC TGAGGAGGAG AGTGAAGAAG CCGACAAGCC CTCAAGCCCG 
GAGGATGGCA GACTGTCAGT ATCATACATA ACAGAGGAAT GCCTGAAGAA GCTGGACACA 
AAGCAGCAGA CCAACACCCT GCTCAACCTG GTGTGGAGGG ACTCTGCGAG CGAGGAGGTC 
TTCACCACCA TGGCCTCCGT CTGCCACACG CTGATGGTGC AGCACCGCAT GATGGTACCC 
AAAGTCAGGC TTCTCTACAG TTTAGCCTTT AATGCCAGGT TTCTGAGACA TCTTTGGTTT 
CTAATATCTT CCATGTCAAC ACGGATGATC ACAGGGTCTA TGGTACCGTT GCTTCAGGTG 
ATATCCAGGG GTTCTCCTAT GTCTTTTGAA GATTCTAGTC GAATCATCCC ACTCTTTTAT 
CTTTTTAGCT CCTTGTTTAG TCATTCACTA ATTTCCATAC ATGATAACGA ATTCTTCGGT 
GATCCCATAG AAGTTGTAGG TCAAAGACAA TCATCAATGA TGCCTTTTAC TTTAGAAGAG 
CTGATAATGT TGTCTCGATG CCTTCGAGAT GCATGCCTGG GGATCATCAA GTTGGCTTAT 
CCAGAAACCA AGCCAGAAGT TCGAGAAGAA TATATTACAG CATTTCAGAG TATTGGAGTT 
ACTACTAGCT CTGAAATGCA ACAATGCATA CAGATGGAAC AGAAAAGATG GATTCAGTTA 
TTTAAGGTTA TCACCAATCT AGTGAAAATG TTGAAGTCCA GAGACACGAG GAGAAATTTT 
TGTCCTCCAA ACCACTGGCT GTCAGAACAA GAAGATATTA AAGCAGATAA GGTCACTCAG 
CTCTATGTGC CAGCATCCAG ACATGTGTGG AGGTTCCGGC GGATGGGGAG GATAGGCCCG 
CTGCAGTCCA CCCTGGACGT GGGTTTGGAG TCCCCGCCGC TGTCTGTGTC TGAGGAAAGA 
CAGCTTGCTG TCCTGACAGA GTTGCCTTTT GTGGTTCCAT TTGAGGAACG AGTAAAGATC 
TTTCAGAGGT TGATTTATGC AGATAAGCAA GAAGTTCAAG GAGATGGTCC ATTTCTGGAT 
GGAATTAATG TCACAATAAG AAGAAATTAC ATTTATGAAG ATGCTTATGA CAAACTTTCT 
CCAGAAAATG AGCCTGATTT GAAAAAGCGG ATCCGTGTGC ACTTGCTCAA TGCCCATGGC 
CTGGATGAAG CTGGCATTGA TGGTGGTGGT ATTTTCAGAG AGTTTTTAAA TGAACTACTG 
AAGTCAGGAT TTAACCCCAA CCAGGGGTTC TTTAAGACTA CTAATGAAGG GCTTCTGTAC 
CCCAACCCGG CTGCTCAGAT GCTTGTGGGA GATTCTTTTG CCAGACATTA CTACTTCCTA 
GGCAGAATGC TTGGAAAGGC TCTCTATGAG AACATGCTGG TGGAGCTGCC CTTTGCAGGC 
TTCTTTCTTT CCAAGTTGCT TGGAACCAGT GCCGACGTGG ACATTCACCA CCTCGCCTCC 
CTAGACCCTG AGGTGTATAA GAATTTGCTC TTTCTGAAGA GCTACGAAGA CGATGTGGAG 
GAGCTTGGGC TGAACTTCAC TGTGGTGAAC AATGACCTGG GAGAGGCGCA GGTAGTTGAA 
CTAAAATTCG GTGGGAAAGA CATCCCTGTC ACCAGCGCCA ACCGGATTGC GTACATCCAC 
TTGGTGGCAG ACTACAGGCT GAACAGGCAG ATCCGCCAGC ACTGCCTGGC TTTCCGCCAG 
GGCCTTGCCA ATGTCGTCAG CCTCGAGTGG CTCCGAATGT TTGATCAGCA AGAAATTCAG 
GTATTAATTT CTGGTGCACA AGTTCCCATA AGCCTAGAGG ACCTAAAATC CTTTACAAAC 
TATTCAGGAG GCTATTCTGC AGACCATCCT GTTATTAAGG TCTTCTGGAG AGTTGTGGAA 
GGGTTCACTG ATGAAGAAAA GCGCAAACTG CTGAAGTTTG TAACAAGCTG CTCTCGACCC 
CCTCTCTTGG GGTTTAAGGA GTTGTATCCC GCATTTTGTA TTCACAACGG AGGCTCCGAC 
CTTGAGCGGC TCCCCACAGC CAGCACCTGC ATGAACCTGC TGAAGCTCCC CGAGTTCTAT 
GACGAGACAC TTTTGCGAAG TAAACTTCTC TATGCGATTG AATGTGCCGC TGGCTTTGAG 
CTGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868307.1
CDS	648..3836
Translation	MEEKASLLHRTQEERRKREEERRRLKNAIIIQSFIRGYRDRKQQYSIQRSAFDRCATLSQSGGAFPIANGPNLTLLVRQLLFFYKQNEDSKRLIWLYQNLIKHSSLFVKQLDGSERLTCLFQIKRLMSLCCRLLQNCNDDSLNVALPMRMLEVFSSENTYLPVLQDASYVVSVIEQILHYMIHNGYYRSLYLLINSKLPSSIEYSDLSRVPIAKILLENVLKPLHFTYNSCPEGARQQVFTAFTEEFLAAPFTDQIFHFIIPALADAQTVFPYEPFLNALLLIESRCSRKSGGAPWLFYFVLTVGENYLGALSEEGLLVYLRVLQTFLSQLPVSPASASCHDSASDSEEESEEADKPSSPEDGRLSVSYITEECLKKLDTKQQTNTLLNLVWRDSASEEVFTTMASVCHTLMVQHRMMVPKVRLLYSLAFNARFLRHLWFLISSMSTRMITGSMVPLLQVISRGSPMSFEDSSRIIPLFYLFSSLFSHSLISIHDNEFFGDPIEVVGQRQSSMMPFTLEELIMLSRCLRDACLGIIKLAYPETKPEVREEYITAFQSIGVTTSSEMQQCIQMEQKRWIQLFKVITNLVKMLKSRDTRRNFCPPNHWLSEQEDIKADKVTQLYVPASRHVWRFRRMGRIGPLQSTLDVGLESPPLSVSEERQLAVLTELPFVVPFEERVKIFQRLIYADKQEVQGDGPFLDGINVTIRRNYIYEDAYDKLSPENEPDLKKRIRVHLLNAHGLDEAGIDGGGIFREFLNELLKSGFNPNQGFFKTTNEGLLYPNPAAQMLVGDSFARHYYFLGRMLGKALYENMLVELPFAGFFLSKLLGTSADVDIHHLASLDPEVYKNLLFLKSYEDDVEELGLNFTVVNNDLGEAQVVELKFGGKDIPVTSANRIAYIHLVADYRLNRQIRQHCLAFRQGLANVVSLEWLRMFDQQEIQVLISGAQVPISLEDLKSFTNYSGGYSADHPVIKVFWRVVEGFTDEEKRKLLKFVTSCSRPPLLGFKELYPAFCIHNGGSDLERLPTASTCMNLLKLPEFYDETLLRSKLLYAIECAAGFELS

Target ORF information:

RefSeq Version	XM_017012818.1
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin protein ligase E3C (UBE3C), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012818.1

ORF Insert Sequence:

ATGGAGGAAA AGGCTTCTCT TTTACATCGT ACTCAGGAAG AAAGAAGAAA GAGAGAGGAA 
GAAAGGCGAA GGTTGAAAAA TGCAATAATT ATCCAGTCAT TTATTCGAGG CTATAGAGAC 
AGAAAACAGC AATATTCCAT CCAAAGAAGT GCATTTGATC GCTGTGCTAC CTTGTCACAG 
TCCGGGGGCG CTTTTCCCAT TGCTAATGGC CCCAACCTTA CCCTTTTGGT AAGGCAGCTT 
CTGTTTTTTT ACAAACAAAA TGAAGACTCA AAACGTTTGA TATGGCTGTA TCAGAACTTA 
ATTAAACACA GCTCTCTGTT TGTCAAGCAG TTGGATGGAT CTGAGAGACT TACATGCTTA 
TTTCAGATAA AAAGATTGAT GAGCCTCTGT TGCAGGTTGC TGCAAAACTG TAATGATGAC 
AGTTTGAATG TTGCACTTCC AATGAGAATG CTTGAAGTAT TTTCGTCTGA GAATACTTAC 
TTGCCTGTTT TACAAGATGC TAGCTATGTG GTGTCAGTGA TTGAACAAAT TTTGCACTAC 
ATGATTCACA ATGGGTATTA TAGGTCTCTA TATTTGTTGA TTAACAGCAA GCTTCCATCA 
AGTATTGAAT ATTCTGATTT ATCTCGAGTT CCTATAGCAA AAATTTTGCT AGAGAATGTT 
CTAAAACCAT TGCACTTTAC TTACAACTCC TGTCCGGAAG GTGCGAGGCA ACAAGTTTTT 
ACAGCCTTCA CAGAGGAGTT TCTGGCAGCA CCTTTTACAG ATCAGATTTT TCATTTCATC 
ATTCCGGCGC TTGCAGATGC GCAGACCGTT TTCCCTTACG AGCCCTTTCT GAATGCACTG 
TTGTTAATAG AGAGTAGATG TTCAAGAAAG AGTGGTGGAG CACCCTGGCT TTTCTATTTC 
GTTTTAACTG TTGGCGAAAA TTATTTGGGG GCCCTCTCTG AGGAAGGGCT GCTGGTGTAT 
TTGCGGGTGC TGCAGACCTT CCTCTCTCAG TTACCAGTCT CTCCTGCCAG CGCGAGCTGT 
CACGACTCAG CCAGTGACTC TGAGGAGGAG AGTGAAGAAG CCGACAAGCC CTCAAGCCCG 
GAGGATGGCA GACTGTCAGT ATCATACATA ACAGAGGAAT GCCTGAAGAA GCTGGACACA 
AAGCAGCAGA CCAACACCCT GCTCAACCTG GTGTGGAGGG ACTCTGCGAG CGAGGAGGTC 
TTCACCACCA TGGCCTCCGT CTGCCACACG CTGATGGTGC AGCACCGCAT GATGGTACCC 
AAAGTCAGGC TTCTCTACAG TTTAGCCTTT AATGCCAGGT TTCTGAGACA TCTTTGGTTT 
CTAATATCTT CCATGTCAAC ACGGATGATC ACAGGGTCTA TGGTACCGTT GCTTCAGGTG 
ATATCCAGGG GTTCTCCTAT GTCTTTTGAA GATTCTAGTC GAATCATCCC ACTCTTTTAT 
CTTTTTAGCT CCTTGTTTAG TCATTCACTA ATTTCCATAC ATGATAACGA ATTCTTCGGT 
GATCCCATAG AAGTTGTAGG TCAAAGACAA TCATCAATGA TGCCTTTTAC TTTAGAAGAG 
CTGATAATGT TGTCTCGATG CCTTCGAGAT GCATGCCTGG GGATCATCAA GTTGGCTTAT 
CCAGAAACCA AGCCAGAAGT TCGAGAAGAA TATATTACAG CATTTCAGAG TATTGGAGTT 
ACTACTAGCT CTGAAATGCA ACAATGCATA CAGATGGAAC AGAAAAGATG GATTCAGTTA 
TTTAAGGTTA TCACCAATCT AGTGAAAATG TTGAAGTCCA GAGACACGAG GAGAAATTTT 
TGTCCTCCAA ACCACTGGCT GTCAGAACAA GAAGATATTA AAGCAGATAA GGTCACTCAG 
CTCTATGTGC CAGCATCCAG ACATGTGTGG AGGTTCCGGC GGATGGGGAG GATAGGCCCG 
CTGCAGTCCA CCCTGGACGT GGGTTTGGAG TCCCCGCCGC TGTCTGTGTC TGAGGAAAGA 
CAGCTTGCTG TCCTGACAGA GTTGCCTTTT GTGGTTCCAT TTGAGGAACG AGTAAAGATC 
TTTCAGAGGT TGATTTATGC AGATAAGCAA GAAGTTCAAG GAGATGGTCC ATTTCTGGAT 
GGAATTAATG TCACAATAAG AAGAAATTAC ATTTATGAAG ATGCTTATGA CAAACTTTCT 
CCAGAAAATG AGCCTGATTT GAAAAAGCGG ATCCGTGTGC ACTTGCTCAA TGCCCATGGC 
CTGGATGAAG CTGGCATTGA TGGTGGTGGT ATTTTCAGAG AGTTTTTAAA TGAACTACTG 
AAGTCAGGAT TTAACCCCAA CCAGGGGTTC TTTAAGACTA CTAATGAAGG GCTTCTGTAC 
CCCAACCCGG CTGCTCAGAT GCTTGTGGGA GATTCTTTTG CCAGACATTA CTACTTCCTA 
GGCAGAATGC TTGGAAAGGC TCTCTATGAG AACATGCTGG TGGAGCTGCC CTTTGCAGGC 
TTCTTTCTTT CCAAGTTGCT TGGAACCAGT GCCGACGTGG ACATTCACCA CCTCGCCTCC 
CTAGACCCTG AGGTGTATAA GAATTTGCTC TTTCTGAAGA GCTACGAAGA CGATGTGGAG 
GAGCTTGGGC TGAACTTCAC TGTGGTGAAC AATGACCTGG GAGAGGCGCA GGTAGTTGAA 
CTAAAATTCG GTGGGAAAGA CATCCCTGTC ACCAGCGCCA ACCGGATTGC GTACATCCAC 
TTGGTGGCAG ACTACAGGCT GAACAGGCAG ATCCGCCAGC ACTGCCTGGC TTTCCGCCAG 
GGCCTTGCCA ATGTCGTCAG CCTCGAGTGG CTCCGAATGT TTGATCAGCA AGAAATTCAG 
GTATTAATTT CTGGTGCACA AGTTCCCATA AGCCTAGAGG ACCTAAAATC CTTTACAAAC 
TATTCAGGAG GCTATTCTGC AGACCATCCT GTTATTAAGG TCTTCTGGAG AGTTGTGGAA 
GGGTTCACTG ATGAAGAAAA GCGCAAACTG CTGAAGTTTG TAACAAGCTG CTCTCGACCC 
CCTCTCTTGG GGTTTAAGGA GTTGTATCCC GCATTTTGTA TTCACAACGG AGGCTCCGAC 
CTTGAGCGGC TCCCCACAGC CAGCACCTGC ATGAACCTGC TGAAGCTCCC CGAGTTCTAT 
GACGAGACAC TTTTGCGAAG TAAACTTCTC TATGCGATTG AATGTGCCGC TGGCTTTGAG 
CTGAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

MiR-542-3p inhibits metastasis and epithelial-mesenchymal transition of hepatocellular carcinoma by targeting UBE3C.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie93420-428(2017 Sep)
Tao J,Liu Z,Wang Y,Wang L,Yao B,Li Q,Wang C,Tu K,Liu Q

Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c.
Proceedings of the National Academy of Sciences of the United States of America114(17)E3404-E3413(2017 Apr)
Kuo CL,Goldberg AL

The ubiquitin ligase UBE4A inhibits prostate cancer progression by targeting interleukin-like EMT inducer (ILEI).
IUBMB life69(1)16-21(2017 01)
Sun Y,Jia X,Gao Q,Liu X,Hou L

Ubiquitin ligase UBE3C promotes melanoma progression by increasing epithelial-mesenchymal transition in melanoma cells.
Oncotarget7(13)15738-46(2016 Mar)
Tang L,Yi XM,Chen J,Chen FJ,Lou W,Gao YL,Zhou J,Su LN,Xu X,Lu JQ,Ma J,Yu N,Ding YF

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UBE3C cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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