APBA3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	APBA3
Entrez Gene ID	9546
Full Name	amyloid beta precursor protein binding family A member 3
Synonyms	MGC:15815,X11L2,mint3
General protein information	Preferred Names amyloid beta precursor protein binding family A member 3 Names amyloid-beta A4 precursor protein-binding family A member 3 amyloid beta A4 precursor protein-binding family A member 3 X11-like 2 protein adapter protein X11gamma amyloid beta (A4) precursor protein-binding, family A, member 3 (X11-like 2) mint-3 neuron-specific X11L2 protein neuronal munc18-1-interacting protein 3 phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.3
Summary	The protein encoded by this gene is a member of the X11 protein family. It is an adapter protein that interacts with the Alzheimer's disease amyloid precursor protein. This gene product is believed to be involved in signal transduction processes. This gene is a candidate gene for Alzheimer's disease. [provided by RefSeq, Jul 2008].
Disorder MIM:	604262

mRNA and Protein(s)

mRNA	Protein	Name
XM_006722950.3	XP_006723013.1	amyloid beta A4 precursor protein-binding family A member 3 isoform X1
XM_006722951.3	XP_006723014.1	amyloid-beta A4 precursor protein-binding family A member 3 isoform X2
XM_006722950.4	XP_006723013.1	amyloid-beta A4 precursor protein-binding family A member 3 isoform X1
NM_004886.3	NP_004877.1	amyloid-beta A4 precursor protein-binding family A member 3
NM_004886.4	NP_004877.1	amyloid-beta A4 precursor protein-binding family A member 3

Pathways from BioSystems

Homologies

Homo sapiens (human)	APBA3	NP_004877.1
	APBA3	XP_001100759.1
Bos taurus (cattle)	APBA3	NP_001029586.1
Rattus norvegicus (Norway rat)	Apba3	NP_113969.1
Gallus gallus (chicken)	APBA3	XP_418188.3
Xenopus tropicalis (tropical clawed frog)	apba3	XP_004911109.1
Pan troglodytes (chimpanzee)	APBA3	XP_001136296.1
Canis lupus familiaris (dog)	APBA3	XP_542171.4
Mus musculus (house mouse)	Apba3	NP_061228.1

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.
Nakaoka HJ, Hara T, Yoshino S, Kanamori A, Matsui Y, Shimamura T, Sato H, Murakami Y, Seiki M, Sakamoto T
Scientific reports622784(2016 Mar)

FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.
Hirose Y, Johnson ZI, Schoepflin ZR, Markova DZ, Chiba K, Toyama Y, Shapiro IM, Risbud MV
The Journal of biological chemistry289(30)20594-605(2014 Jul)

Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ? generation.
Sullivan SE, Dillon GM, Sullivan JM, Ho A
The Journal of biological chemistry289(22)15374-83(2014 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that NECAB3, a novel Mint3-binding protein, activates HIF-1 to promote normoxic glycolysis and tumorigenicity by forming a ternary complex with Mint3 and FIH-1.
Title: NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.

FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.
Title: FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.

Mints are necessary for activity-induced APP and PS1 trafficking and provide insight into the cellular fate of APP in endocytic pathways essential for Abeta production.
Title: Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ? generation.

Strict specificity for recruitment of the Mint3 adaptor by APP at the Golgi, a critical role for Tyr-682 (within the YENPTY motif) in Mint3 recruitment and export of APP from the Golgi, are demonstrated.
Title: Recruitment of the Mint3 adaptor is necessary for export of the amyloid precursor protein (APP) from the Golgi complex.

These results indicate that all three amyloid beta protein precursor family members are capable of activating gene transcription via Mint3-Taz and Mint3-Yap.
Title: Signaling via amyloid precursor-like proteins APLP1 and APLP2.

The following APBA3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the APBA3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04669	NM_004886.4 Latest version!	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu51916	XM_006722950.4 Latest version!	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu51917	XM_006722951.3 Latest version!	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
View Old Accession Versions >>
OHu51916	XM_006722950.3	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu04669	NM_004886.3	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

APBA3 ( NM_004886.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_004877.1 Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.

Price & Availability↑

CloneID	OHu04669
Clone ID Related Accession (Same CDS sequence)	NM_004886.3 , NM_004886.4
Accession Version	NM_004886.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	amyloid-beta A4 precursor protein-binding family A member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI910038.1, AB021638.1, BM977984.1, BG938716.1 and BQ707748.1. On Apr 7, 2004 this sequence version replaced NM_004886.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.235058.1, SRR1163657.278287.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: full length.

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC 
CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC 
CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT 
GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004877.1
CDS	178..1905
Translation	MDFPTISRSPSGPPAMDLEGPRDILVPSEDLTPDSQWDPMPGGPGSLSRMELDESSLQELVQQFEALPGDLVGPSPGGAPCPLHIATGHGLASQEIADAHGLLSAEAGRDDLLGLLHCEECPPSQTGPEEPLEPAPRLLQPPEDPDEDSDSPEWVEGASAEQEGSRSSSSSPEPWLETVPLVTPEEPPAGAQSPETLASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQDHGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPSQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL

Target ORF information:

RefSeq Version	NM_004886.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004886.3

ORF Insert Sequence:

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC 
CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC 
CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT 
GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APBA3 ( NM_004886.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004877.1 Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.

Price & Availability↑

CloneID	OHu04669
Clone ID Related Accession (Same CDS sequence)	NM_004886.3 , NM_004886.4
Accession Version	NM_004886.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1728bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	amyloid-beta A4 precursor protein-binding family A member 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC005954.1, BI910038.1, AB021638.1, BM977984.1, BG938716.1 and BQ707748.1. On Nov 24, 2018 this sequence version replaced NM_004886.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.235058.1, SRR1163657.278287.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000316757.4/ ENSP00000315136.2 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC 
CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC 
CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT 
GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004877.1
CDS	195..1922
Translation	MDFPTISRSPSGPPAMDLEGPRDILVPSEDLTPDSQWDPMPGGPGSLSRMELDESSLQELVQQFEALPGDLVGPSPGGAPCPLHIATGHGLASQEIADAHGLLSAEAGRDDLLGLLHCEECPPSQTGPEEPLEPAPRLLQPPEDPDEDSDSPEWVEGASAEQEGSRSSSSSPEPWLETVPLVTPEEPPAGAQSPETLASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQDHGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPSQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL

Target ORF information:

RefSeq Version	NM_004886.4
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004886.4

ORF Insert Sequence:

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCATCTG CAGCCTCCTC CGTGGTGGCA TCGCCGAGCG TGGGGGCATC 
CGCGTCGGCC ACCGCATCAT TGAGATCAAT GGGCAGAGTG TGGTGGCCAC GCCACACGCC 
CGCATCATCG AGCTGCTCAC CGAGGCCTAT GGCGAGGTGC ATATCAAGAC GATGCCAGCT 
GCCACATATC GCCTCCTTAC AGGCCAGGAG CAGCCCGTGT ACCTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APBA3 ( XM_006722950.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723013.1 Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51916
Clone ID Related Accession (Same CDS sequence)	XM_006722950.3 , XM_006722950.4
Accession Version	XM_006722950.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	amyloid beta A4 precursor protein-binding family A member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006722950.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCGTGAG GCCCCGGCCC CTGGCCCCGG GGTGGGGGGG TAGGGCGGCC 
CTGAGCACGG CCCCTGAGCA GCCCCCACCT CTTTCCCGTC CCCCTCTTTT CTCCCCCAGA 
TCTGCAGCCT CCTCCGTGGT GGCATCGCCG AGCGTGGGGG CATCCGCGTC GGCCACCGCA 
TCATTGAGAT CAATGGGCAG AGTGTGGTGG CCACGCCACA CGCCCGCATC ATCGAGCTGC 
TCACCGAGGC CTATGGCGAG GTGCATATCA AGACGATGCC AGCTGCCACA TATCGCCTCC 
TTACAGGCCA GGAGCAGCCC GTGTACCTGT GACCACCTCA TCCCTTGCCT GCCACTGTGC 
CTTCGCCTCC ATGGCCCCGG AGCCCCATCC TGGGCCTGCC CTGGCTGGCC AGGACCCCAG 
CGGTTCTTGG TCCTGTATGA TTTCCTAATA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723013.1
CDS	200..2152
Translation	MDFPTISRSPSGPPAMDLEGPRDILVPSEDLTPDSQWDPMPGGPGSLSRMELDESSLQELVQQFEALPGDLVGPSPGGAPCPLHIATGHGLASQEIADAHGLLSAEAGRDDLLGLLHCEECPPSQTGPEEPLEPAPRLLQPPEDPDEDSDSPEWVEGASAEQEGSRSSSSSPEPWLETVPLVTPEEPPAGAQSPETLASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQDHGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPSQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIVRPRPLAPGWGGRAALSTAPEQPPPLSRPPLFSPRSAASSVVASPSVGASASATASLRSMGRVWWPRHTPASSSCSPRPMARCISRRCQLPHIASLQARSSPCTCDHLIPCLPLCLRLHGPGAPSWACPGWPGPQRFLVLYDFLI

Target ORF information:

RefSeq Version	XM_006722950.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722950.3

ORF Insert Sequence:

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCGTGAG GCCCCGGCCC CTGGCCCCGG GGTGGGGGGG TAGGGCGGCC 
CTGAGCACGG CCCCTGAGCA GCCCCCACCT CTTTCCCGTC CCCCTCTTTT CTCCCCCAGA 
TCTGCAGCCT CCTCCGTGGT GGCATCGCCG AGCGTGGGGG CATCCGCGTC GGCCACCGCA 
TCATTGAGAT CAATGGGCAG AGTGTGGTGG CCACGCCACA CGCCCGCATC ATCGAGCTGC 
TCACCGAGGC CTATGGCGAG GTGCATATCA AGACGATGCC AGCTGCCACA TATCGCCTCC 
TTACAGGCCA GGAGCAGCCC GTGTACCTGT GACCACCTCA TCCCTTGCCT GCCACTGTGC 
CTTCGCCTCC ATGGCCCCGG AGCCCCATCC TGGGCCTGCC CTGGCTGGCC AGGACCCCAG 
CGGTTCTTGG TCCTGTATGA TTTCCTAATA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APBA3 ( XM_006722950.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723013.1 Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu51916
Clone ID Related Accession (Same CDS sequence)	XM_006722950.3 , XM_006722950.4
Accession Version	XM_006722950.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1953bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amyloid-beta A4 precursor protein-binding family A member 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_006722950.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCGTGAG GCCCCGGCCC CTGGCCCCGG GGTGGGGGGG TAGGGCGGCC 
CTGAGCACGG CCCCTGAGCA GCCCCCACCT CTTTCCCGTC CCCCTCTTTT CTCCCCCAGA 
TCTGCAGCCT CCTCCGTGGT GGCATCGCCG AGCGTGGGGG CATCCGCGTC GGCCACCGCA 
TCATTGAGAT CAATGGGCAG AGTGTGGTGG CCACGCCACA CGCCCGCATC ATCGAGCTGC 
TCACCGAGGC CTATGGCGAG GTGCATATCA AGACGATGCC AGCTGCCACA TATCGCCTCC 
TTACAGGCCA GGAGCAGCCC GTGTACCTGT GACCACCTCA TCCCTTGCCT GCCACTGTGC 
CTTCGCCTCC ATGGCCCCGG AGCCCCATCC TGGGCCTGCC CTGGCTGGCC AGGACCCCAG 
CGGTTCTTGG TCCTGTATGA TTTCCTAATA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723013.1
CDS	199..2151
Translation	MDFPTISRSPSGPPAMDLEGPRDILVPSEDLTPDSQWDPMPGGPGSLSRMELDESSLQELVQQFEALPGDLVGPSPGGAPCPLHIATGHGLASQEIADAHGLLSAEAGRDDLLGLLHCEECPPSQTGPEEPLEPAPRLLQPPEDPDEDSDSPEWVEGASAEQEGSRSSSSSPEPWLETVPLVTPEEPPAGAQSPETLASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRMAQAREAMDRVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQDHGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPSQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIVRPRPLAPGWGGRAALSTAPEQPPPLSRPPLFSPRSAASSVVASPSVGASASATASLRSMGRVWWPRHTPASSSCSPRPMARCISRRCQLPHIASLQARSSPCTCDHLIPCLPLCLRLHGPGAPSWACPGWPGPQRFLVLYDFLI

Target ORF information:

RefSeq Version	XM_006722950.4
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722950.4

ORF Insert Sequence:

ATGGACTTCC CCACAATTTC CCGATCCCCT TCGGGGCCTC CAGCCATGGA CTTGGAGGGG 
CCCAGGGACA TTCTTGTGCC TTCGGAGGAC CTCACCCCTG ACAGCCAGTG GGACCCTATG 
CCAGGAGGCC CCGGCAGCCT CAGTCGGATG GAACTTGATG AGTCAAGCCT TCAGGAGCTG 
GTGCAGCAGT TTGAAGCTCT GCCAGGCGAT CTGGTGGGCC CATCCCCAGG TGGAGCCCCC 
TGTCCCCTAC ACATTGCCAC AGGCCATGGC CTGGCCTCCC AGGAGATTGC TGATGCCCAC 
GGGCTCCTGT CTGCCGAAGC TGGCCGGGAT GACCTGCTGG GCCTCTTGCA CTGCGAGGAA 
TGCCCGCCTT CCCAGACTGG TCCTGAAGAG CCTCTAGAGC CTGCCCCCCG ACTGTTGCAG 
CCCCCTGAGG ACCCAGATGA GGATTCTGAC TCCCCAGAAT GGGTGGAGGG GGCCTCTGCT 
GAGCAGGAGG GCAGCAGGAG CTCAAGCAGT TCCCCGGAAC CCTGGCTGGA GACGGTGCCT 
CTAGTCACAC CTGAAGAGCC ACCCGCTGGT GCCCAGAGCC CCGAGACCCT GGCTTCCTAC 
CCTGCCCCCC AGGAGGTGCC TGGTCCCTGT GACCATGAAG ACCTCCTGGA CGGTGTCATA 
TTTGGGGCCA GGTACCTGGG GTCCACCCAG CTGGTGTCGG AACGGAACCC GCCCACCAGC 
ACGCGCATGG CCCAGGCCCG GGAGGCCATG GACCGCGTCA AGGCCCCCGA TGGGGAGACC 
CAGCCCATGA CGGAGGTGGA CCTGTTCGTC TCCACCAAGA GGATCAAGGT CTTGACAGCG 
GACTCCCAGG AGGCCATGAT GGACCACGCC CTGCATACCA TCTCCTACAC AGCCGACATC 
GGCTGCGTGC TGGTGCTGAT GGCGCGGCGG CGGCTGGCAC GGAGGCCGGC ACCCCAGGAC 
CACGGCCGCC GCCTCTACAA GATGCTCTGC CACGTATTCT ACGCGGAGGA CGCCCAGCTC 
ATCGCCCAGG CCATTGGCCA GGCCTTCGCC GCCGCCTACA GCCAGTTCCT ACGGGAAAGC 
GGTATTGACC CCAGCCAGGT GGGCGTGCAC CCGAGCCCAG GCGCCTGCCA CCTCCATAAT 
GGGGACCTGG ACCACTTCTC CAACAGTGAC AACTGCCGGG AGGTGCACCT CGAGAAGCGG 
CGAGGGGAGG GCCTGGGCGT GGCCCTGGTG GAGTCGGGCT GGGGCTCCCT GCTGCCCACA 
GCCGTCATCG CCAACCTGCT GCACGGGGGG CCTGCTGAGC GCTCGGGGGC CCTCAGCATC 
GGGGACCGCC TGACCGCCAT CAACGGGACC AGCCTGGTGG GGCTGCCCCT GGCTGCGTGC 
CAGGCCGCTG TCCGCGAGAC GAAGTCGCAG ACGTCGGTGA CACTCAGCAT CGTCCACTGC 
CCTCCCGTCA CCACCGCCAT CATCCACCGG CCCCACGCCC GCGAGCAGCT GGGCTTCTGC 
GTGGAGGACG GCATCGTGAG GCCCCGGCCC CTGGCCCCGG GGTGGGGGGG TAGGGCGGCC 
CTGAGCACGG CCCCTGAGCA GCCCCCACCT CTTTCCCGTC CCCCTCTTTT CTCCCCCAGA 
TCTGCAGCCT CCTCCGTGGT GGCATCGCCG AGCGTGGGGG CATCCGCGTC GGCCACCGCA 
TCATTGAGAT CAATGGGCAG AGTGTGGTGG CCACGCCACA CGCCCGCATC ATCGAGCTGC 
TCACCGAGGC CTATGGCGAG GTGCATATCA AGACGATGCC AGCTGCCACA TATCGCCTCC 
TTACAGGCCA GGAGCAGCCC GTGTACCTGT GACCACCTCA TCCCTTGCCT GCCACTGTGC 
CTTCGCCTCC ATGGCCCCGG AGCCCCATCC TGGGCCTGCC CTGGCTGGCC AGGACCCCAG 
CGGTTCTTGG TCCTGTATGA TTTCCTAATA TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

APBA3 ( XM_006722951.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_006723014.1 Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu51917
Clone ID Related Accession (Same CDS sequence)	XM_006722951.3
Accession Version	XM_006722951.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1227bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	amyloid-beta A4 precursor protein-binding family A member 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000019.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006722951.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCCAGG CCCGGGAGGC CATGGACCGC GTCAAGGCCC CCGATGGGGA GACCCAGCCC 
ATGACGGAGG TGGACCTGTT CGTCTCCACC AAGAGGATCA AGGTCTTGAC AGCGGACTCC 
CAGGAGGCCA TGATGGACCA CGCCCTGCAT ACCATCTCCT ACACAGCCGA CATCGGCTGC 
GTGCTGGTGC TGATGGCGCG GCGGCGGCTG GCACGGAGGC CGGCACCCCA GGACCACGGC 
CGCCGCCTCT ACAAGATGCT CTGCCACGTA TTCTACGCGG AGGACGCCCA GCTCATCGCC 
CAGGCCATTG GCCAGGCCTT CGCCGCCGCC TACAGCCAGT TCCTACGGGA AAGCGGTATT 
GACCCCAGCC AGGTGGGCGT GCACCCGAGC CCAGGCGCCT GCCACCTCCA TAATGGGGAC 
CTGGACCACT TCTCCAACAG TGACAACTGC CGGGAGGTGC ACCTCGAGAA GCGGCGAGGG 
GAGGGCCTGG GCGTGGCCCT GGTGGAGTCG GGCTGGGGCT CCCTGCTGCC CACAGCCGTC 
ATCGCCAACC TGCTGCACGG GGGGCCTGCT GAGCGCTCGG GGGCCCTCAG CATCGGGGAC 
CGCCTGACCG CCATCAACGG GACCAGCCTG GTGGGGCTGC CCCTGGCTGC GTGCCAGGCC 
GCTGTCCGCG AGACGAAGTC GCAGACGTCG GTGACACTCA GCATCGTCCA CTGCCCTCCC 
GTCACCACCG CCATCATCCA CCGGCCCCAC GCCCGCGAGC AGCTGGGCTT CTGCGTGGAG 
GACGGCATCG TGAGGCCCCG GCCCCTGGCC CCGGGGTGGG GGGGTAGGGC GGCCCTGAGC 
ACGGCCCCTG AGCAGCCCCC ACCTCTTTCC CGTCCCCCTC TTTTCTCCCC CAGATCTGCA 
GCCTCCTCCG TGGTGGCATC GCCGAGCGTG GGGGCATCCG CGTCGGCCAC CGCATCATTG 
AGATCAATGG GCAGAGTGTG GTGGCCACGC CACACGCCCG CATCATCGAG CTGCTCACCG 
AGGCCTATGG CGAGGTGCAT ATCAAGACGA TGCCAGCTGC CACATATCGC CTCCTTACAG 
GCCAGGAGCA GCCCGTGTAC CTGTGACCAC CTCATCCCTT GCCTGCCACT GTGCCTTCGC 
CTCCATGGCC CCGGAGCCCC ATCCTGGGCC TGCCCTGGCT GGCCAGGACC CCAGCGGTTC 
TTGGTCCTGT ATGATTTCCT AATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006723014.1
CDS	611..1837
Translation	MAQAREAMDRVKAPDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHALHTISYTADIGCVLVLMARRRLARRPAPQDHGRRLYKMLCHVFYAEDAQLIAQAIGQAFAAAYSQFLRESGIDPSQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEKRRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAACQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIVRPRPLAPGWGGRAALSTAPEQPPPLSRPPLFSPRSAASSVVASPSVGASASATASLRSMGRVWWPRHTPASSSCSPRPMARCISRRCQLPHIASLQARSSPCTCDHLIPCLPLCLRLHGPGAPSWACPGWPGPQRFLVLYDFLI

Target ORF information:

RefSeq Version	XM_006722951.3
Organism	Homo sapiens(human)
Definition	Homo sapiens amyloid beta precursor protein binding family A member 3 (APBA3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006722951.3

ORF Insert Sequence:

ATGGCCCAGG CCCGGGAGGC CATGGACCGC GTCAAGGCCC CCGATGGGGA GACCCAGCCC 
ATGACGGAGG TGGACCTGTT CGTCTCCACC AAGAGGATCA AGGTCTTGAC AGCGGACTCC 
CAGGAGGCCA TGATGGACCA CGCCCTGCAT ACCATCTCCT ACACAGCCGA CATCGGCTGC 
GTGCTGGTGC TGATGGCGCG GCGGCGGCTG GCACGGAGGC CGGCACCCCA GGACCACGGC 
CGCCGCCTCT ACAAGATGCT CTGCCACGTA TTCTACGCGG AGGACGCCCA GCTCATCGCC 
CAGGCCATTG GCCAGGCCTT CGCCGCCGCC TACAGCCAGT TCCTACGGGA AAGCGGTATT 
GACCCCAGCC AGGTGGGCGT GCACCCGAGC CCAGGCGCCT GCCACCTCCA TAATGGGGAC 
CTGGACCACT TCTCCAACAG TGACAACTGC CGGGAGGTGC ACCTCGAGAA GCGGCGAGGG 
GAGGGCCTGG GCGTGGCCCT GGTGGAGTCG GGCTGGGGCT CCCTGCTGCC CACAGCCGTC 
ATCGCCAACC TGCTGCACGG GGGGCCTGCT GAGCGCTCGG GGGCCCTCAG CATCGGGGAC 
CGCCTGACCG CCATCAACGG GACCAGCCTG GTGGGGCTGC CCCTGGCTGC GTGCCAGGCC 
GCTGTCCGCG AGACGAAGTC GCAGACGTCG GTGACACTCA GCATCGTCCA CTGCCCTCCC 
GTCACCACCG CCATCATCCA CCGGCCCCAC GCCCGCGAGC AGCTGGGCTT CTGCGTGGAG 
GACGGCATCG TGAGGCCCCG GCCCCTGGCC CCGGGGTGGG GGGGTAGGGC GGCCCTGAGC 
ACGGCCCCTG AGCAGCCCCC ACCTCTTTCC CGTCCCCCTC TTTTCTCCCC CAGATCTGCA 
GCCTCCTCCG TGGTGGCATC GCCGAGCGTG GGGGCATCCG CGTCGGCCAC CGCATCATTG 
AGATCAATGG GCAGAGTGTG GTGGCCACGC CACACGCCCG CATCATCGAG CTGCTCACCG 
AGGCCTATGG CGAGGTGCAT ATCAAGACGA TGCCAGCTGC CACATATCGC CTCCTTACAG 
GCCAGGAGCA GCCCGTGTAC CTGTGACCAC CTCATCCCTT GCCTGCCACT GTGCCTTCGC 
CTCCATGGCC CCGGAGCCCC ATCCTGGGCC TGCCCTGGCT GGCCAGGACC CCAGCGGTTC 
TTGGTCCTGT ATGATTTCCT AATATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

NECAB3 Promotes Activation of Hypoxia-inducible factor-1 during Normoxia and Enhances Tumourigenicity of Cancer Cells.
Scientific reports622784(2016 Mar)
Nakaoka HJ,Hara T,Yoshino S,Kanamori A,Matsui Y,Shimamura T,Sato H,Murakami Y,Seiki M,Sakamoto T

FIH-1-Mint3 axis does not control HIF-1 transcriptional activity in nucleus pulposus cells.
The Journal of biological chemistry289(30)20594-605(2014 Jul)
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Mint proteins are required for synaptic activity-dependent amyloid precursor protein (APP) trafficking and amyloid ? generation.
The Journal of biological chemistry289(22)15374-83(2014 May)
Sullivan SE,Dillon GM,Sullivan JM,Ho A

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APBA3 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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