ACVR2B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ACVR2B
Entrez Gene ID	93
Full Name	activin A receptor type 2B
Synonyms	ACTRIIB,ActR-IIB,HTX4
General protein information	Preferred Names activin A receptor type 2B Names activin receptor type-2B activin A receptor, type IIB
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p22.2
Summary	Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor. [provided by RefSeq, Jul 2008].
Disorder MIM:	602730
Disorder Html:	Heterotaxy, visceral, 4, autosomal, 613751 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017007514.1	XP_016863003.1	activin receptor type-2B isoform X2
XM_005265583.2	XP_005265640.1	activin receptor type-2B isoform X1
XM_005265583.3	XP_005265640.1	activin receptor type-2B isoform X1
XM_017007515.2	XP_016863004.1	activin receptor type-2B isoform X3
XM_017007516.1	XP_016863005.1	activin receptor type-2B isoform X4
NM_001106.3	NP_001097.2	activin receptor type-2B precursor
XM_017007515.1	XP_016863004.1	activin receptor type-2B isoform X3
NM_001106.4	NP_001097.2	activin receptor type-2B precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	ACVR2B	XP_542709.2
Homo sapiens (human)	ACVR2B	NP_001097.2
Bos taurus (cattle)	ACVR2B	NP_776920.1
Gallus gallus (chicken)	ACVR2B	NP_989648.1
	ACVR2B	XP_001084713.1
Danio rerio (zebrafish)	acvr2b	NP_571285.1
Pan troglodytes (chimpanzee)	ACVR2B	XP_516369.2
Mus musculus (house mouse)	Acvr2b	NP_031423.1
Rattus norvegicus (Norway rat)	Acvr2b	NP_113742.1
Xenopus tropicalis (tropical clawed frog)	acvr2b	NP_001006871.1

Gene Ontology
Bibliography

Related articles in PubMed

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.
Cassar L, Nicholls C, Pinto AR, Chen R, Wang L, Li H, Liu JP
Protein & cell8(1)39-54(2017 Jan)

Genetic Variant in ACVR2B Is Associated with Lean Mass.
Klimentidis YC, Bea JW, Thompson P, Klimecki WT, Hu C, Wu G, Nicholas JS, Ryckman KK, Chen Z
Medicine and science in sports and exercise48(7)1270-5(2016 07)

NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients.
Tian RH, Yang S, Zhu ZJ, Wang JL, Liu Y, Yao C, Ma M, Guo Y, Yuan Q, Hai Y, Huang YR, He Z, Li Z
Asian journal of andrology17(6)996-1005(2015 Nov-Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.(
Title: TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.

the A allele of genetic variant rs2276541 in ACVR2B is associated with lean muscle mass
Title: Genetic Variant in ACVR2B Is Associated with Lean Mass.

ActR-IIB is expressed in male germ cells and Sertoli cells.
Title: NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients.

Adenomyotic tissues express high levels of myostatin, follistatin, and activin type II receptors.
Title: Myostatin, follistatin and activin type II receptors are highly expressed in adenomyosis.

Activin A inhibited signaling by BMP-6 and BMP-9 by competing for type 2 receptors ACVR2A and ACVR2B.
Title: Activin A inhibits BMP-signaling by binding ACVR2A and ACVR2B.

The following ACVR2B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ACVR2B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu18179	NM_001106.4 Latest version!	Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$214.50-$300.30 $429.00
OHu37602	XM_005265583.3 Latest version!	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu94785	XM_017007514.1 Latest version!	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu94786	XM_017007515.2 Latest version!	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu94787	XM_017007516.1 Latest version!	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu37602	XM_005265583.2	Homo sapiens activin A receptor, type IIB (ACVR2B), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00
OHu94786	XM_017007515.1	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu18179	NM_001106.3	Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$214.50-$300.30 $429.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ACVR2B ( NM_001106.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001097.2 Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.

Price & Availability↑

CloneID	OHu18179
Clone ID Related Accession (Same CDS sequence)	NM_001106.3 , NM_001106.4
Accession Version	NM_001106.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	activin receptor type-2B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006191.1, BC099642.4 and BP352716.1. This sequence is a reference standard in the RefSeqGene project. On Oct 26, 2006 this sequence version replaced NM_001106.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X77533.1, BC099642.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACGGCGC CCTGGGTGGC CCTCGCCCTC CTCTGGGGAT CGCTGTGCGC CGGCTCTGGG 
CGTGGGGAGG CTGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAA GGCGAGCAGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC TGGCACCATC GAGCTCGTGA AGAAGGGCTG CTGGCTAGAT 
GACTTCAACT GCTACGATAG GCAGGAGTGT GTGGCCACTG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GTGAAGGCAA CTTCTGCAAC GAACGCTTCA CTCATTTGCC AGAGGCTGGG 
GGCCCGGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC GGTGCTGGCC 
TACTCACTGC TGCCCATCGG GGGCCTTTCC CTCATCGTCC TGCTGGCCTT TTGGATGTAC 
CGGCATCGCA AGCCCCCCTA CGGTCATGTG GACATCCATG AGGACCCTGG GCCTCCACCA 
CCATCCCCTC TGGTGGGCCT GAAGCCACTG CAGCTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGCTGTG TCTGGAAGGC CCAGCTCATG AATGACTTTG TAGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAA CGGGAGATCT TCAGCACACC TGGCATGAAG 
CACGAGAACC TGCTACAGTT CATTGCTGCC GAGAAGCGAG GCTCCAACCT CGAAGTAGAG 
CTGTGGCTCA TCACGGCCTT CCATGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCATGTA GCAGAGACGA TGTCACGAGG CCTCTCATAC 
CTGCATGAGG ATGTGCCCTG GTGCCGTGGC GAGGGCCACA AGCCGTCTAT TGCCCACAGG 
GACTTTAAAA GTAAGAATGT ATTGCTGAAG AGCGACCTCA CAGCCGTGCT GGCTGACTTT 
GGCTTGGCTG TTCGATTTGA GCCAGGGAAA CCTCCAGGGG ACACCCACGG ACAGGTAGGC 
ACGAGACGGT ACATGGCTCC TGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGATGCC 
TTCCTGCGCA TTGACATGTA TGCCATGGGG TTGGTGCTGT GGGAGCTTGT GTCTCGCTGC 
AAGGCTGCAG ACGGACCCGT GGATGAGTAC ATGCTGCCCT TTGAGGAAGA GATTGGCCAG 
CACCCTTCGT TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGAG GCCCACCATT 
AAAGATCACT GGTTGAAACA CCCGGGCCTG GCCCAGCTTT GTGTGACCAT CGAGGAGTGC 
TGGGACCATG ATGCAGAGGC TCGCTTGTCC GCGGGCTGTG TGGAGGAGCG GGTGTCCCTG 
ATTCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTCG TTTCCCTGGT GACCTCTGTC 
ACCAATGTGG ACCTGCCCCC TAAAGAGTCA AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001097.2
CDS	25..1563
Translation	MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	NM_001106.3
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106.3

ORF Insert Sequence:

ATGACGGCGC CCTGGGTGGC CCTCGCCCTC CTCTGGGGAT CGCTGTGCGC CGGCTCTGGG 
CGTGGGGAGG CTGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAA GGCGAGCAGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC TGGCACCATC GAGCTCGTGA AGAAGGGCTG CTGGCTAGAT 
GACTTCAACT GCTACGATAG GCAGGAGTGT GTGGCCACTG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GTGAAGGCAA CTTCTGCAAC GAACGCTTCA CTCATTTGCC AGAGGCTGGG 
GGCCCGGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC GGTGCTGGCC 
TACTCACTGC TGCCCATCGG GGGCCTTTCC CTCATCGTCC TGCTGGCCTT TTGGATGTAC 
CGGCATCGCA AGCCCCCCTA CGGTCATGTG GACATCCATG AGGACCCTGG GCCTCCACCA 
CCATCCCCTC TGGTGGGCCT GAAGCCACTG CAGCTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGCTGTG TCTGGAAGGC CCAGCTCATG AATGACTTTG TAGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAA CGGGAGATCT TCAGCACACC TGGCATGAAG 
CACGAGAACC TGCTACAGTT CATTGCTGCC GAGAAGCGAG GCTCCAACCT CGAAGTAGAG 
CTGTGGCTCA TCACGGCCTT CCATGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCATGTA GCAGAGACGA TGTCACGAGG CCTCTCATAC 
CTGCATGAGG ATGTGCCCTG GTGCCGTGGC GAGGGCCACA AGCCGTCTAT TGCCCACAGG 
GACTTTAAAA GTAAGAATGT ATTGCTGAAG AGCGACCTCA CAGCCGTGCT GGCTGACTTT 
GGCTTGGCTG TTCGATTTGA GCCAGGGAAA CCTCCAGGGG ACACCCACGG ACAGGTAGGC 
ACGAGACGGT ACATGGCTCC TGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGATGCC 
TTCCTGCGCA TTGACATGTA TGCCATGGGG TTGGTGCTGT GGGAGCTTGT GTCTCGCTGC 
AAGGCTGCAG ACGGACCCGT GGATGAGTAC ATGCTGCCCT TTGAGGAAGA GATTGGCCAG 
CACCCTTCGT TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGAG GCCCACCATT 
AAAGATCACT GGTTGAAACA CCCGGGCCTG GCCCAGCTTT GTGTGACCAT CGAGGAGTGC 
TGGGACCATG ATGCAGAGGC TCGCTTGTCC GCGGGCTGTG TGGAGGAGCG GGTGTCCCTG 
ATTCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTCG TTTCCCTGGT GACCTCTGTC 
ACCAATGTGG ACCTGCCCCC TAAAGAGTCA AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( NM_001106.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_001097.2 Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.

Price & Availability↑

CloneID	OHu18179
Clone ID Related Accession (Same CDS sequence)	NM_001106.3 , NM_001106.4
Accession Version	NM_001106.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1539bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	activin receptor type-2B precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP006191.1, BC099642.4 and BP352716.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_001106.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X77533.1, BC099642.4 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000352511.5/ ENSP00000340361.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACGGCGC CCTGGGTGGC CCTCGCCCTC CTCTGGGGAT CGCTGTGCGC CGGCTCTGGG 
CGTGGGGAGG CTGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAA GGCGAGCAGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC TGGCACCATC GAGCTCGTGA AGAAGGGCTG CTGGCTAGAT 
GACTTCAACT GCTACGATAG GCAGGAGTGT GTGGCCACTG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GTGAAGGCAA CTTCTGCAAC GAACGCTTCA CTCATTTGCC AGAGGCTGGG 
GGCCCGGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC GGTGCTGGCC 
TACTCACTGC TGCCCATCGG GGGCCTTTCC CTCATCGTCC TGCTGGCCTT TTGGATGTAC 
CGGCATCGCA AGCCCCCCTA CGGTCATGTG GACATCCATG AGGACCCTGG GCCTCCACCA 
CCATCCCCTC TGGTGGGCCT GAAGCCACTG CAGCTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGCTGTG TCTGGAAGGC CCAGCTCATG AATGACTTTG TAGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAA CGGGAGATCT TCAGCACACC TGGCATGAAG 
CACGAGAACC TGCTACAGTT CATTGCTGCC GAGAAGCGAG GCTCCAACCT CGAAGTAGAG 
CTGTGGCTCA TCACGGCCTT CCATGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCATGTA GCAGAGACGA TGTCACGAGG CCTCTCATAC 
CTGCATGAGG ATGTGCCCTG GTGCCGTGGC GAGGGCCACA AGCCGTCTAT TGCCCACAGG 
GACTTTAAAA GTAAGAATGT ATTGCTGAAG AGCGACCTCA CAGCCGTGCT GGCTGACTTT 
GGCTTGGCTG TTCGATTTGA GCCAGGGAAA CCTCCAGGGG ACACCCACGG ACAGGTAGGC 
ACGAGACGGT ACATGGCTCC TGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGATGCC 
TTCCTGCGCA TTGACATGTA TGCCATGGGG TTGGTGCTGT GGGAGCTTGT GTCTCGCTGC 
AAGGCTGCAG ACGGACCCGT GGATGAGTAC ATGCTGCCCT TTGAGGAAGA GATTGGCCAG 
CACCCTTCGT TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGAG GCCCACCATT 
AAAGATCACT GGTTGAAACA CCCGGGCCTG GCCCAGCTTT GTGTGACCAT CGAGGAGTGC 
TGGGACCATG ATGCAGAGGC TCGCTTGTCC GCGGGCTGTG TGGAGGAGCG GGTGTCCCTG 
ATTCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTCG TTTCCCTGGT GACCTCTGTC 
ACCAATGTGG ACCTGCCCCC TAAAGAGTCA AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001097.2
CDS	434..1972
Translation	MTAPWVALALLWGSLCAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	NM_001106.4
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001106.4

ORF Insert Sequence:

ATGACGGCGC CCTGGGTGGC CCTCGCCCTC CTCTGGGGAT CGCTGTGCGC CGGCTCTGGG 
CGTGGGGAGG CTGAGACACG GGAGTGCATC TACTACAACG CCAACTGGGA GCTGGAGCGC 
ACCAACCAGA GCGGCCTGGA GCGCTGCGAA GGCGAGCAGG ACAAGCGGCT GCACTGCTAC 
GCCTCCTGGC GCAACAGCTC TGGCACCATC GAGCTCGTGA AGAAGGGCTG CTGGCTAGAT 
GACTTCAACT GCTACGATAG GCAGGAGTGT GTGGCCACTG AGGAGAACCC CCAGGTGTAC 
TTCTGCTGCT GTGAAGGCAA CTTCTGCAAC GAACGCTTCA CTCATTTGCC AGAGGCTGGG 
GGCCCGGAAG TCACGTACGA GCCACCCCCG ACAGCCCCCA CCCTGCTCAC GGTGCTGGCC 
TACTCACTGC TGCCCATCGG GGGCCTTTCC CTCATCGTCC TGCTGGCCTT TTGGATGTAC 
CGGCATCGCA AGCCCCCCTA CGGTCATGTG GACATCCATG AGGACCCTGG GCCTCCACCA 
CCATCCCCTC TGGTGGGCCT GAAGCCACTG CAGCTGCTGG AGATCAAGGC TCGGGGGCGC 
TTTGGCTGTG TCTGGAAGGC CCAGCTCATG AATGACTTTG TAGCTGTCAA GATCTTCCCA 
CTCCAGGACA AGCAGTCGTG GCAGAGTGAA CGGGAGATCT TCAGCACACC TGGCATGAAG 
CACGAGAACC TGCTACAGTT CATTGCTGCC GAGAAGCGAG GCTCCAACCT CGAAGTAGAG 
CTGTGGCTCA TCACGGCCTT CCATGACAAG GGCTCCCTCA CGGATTACCT CAAGGGGAAC 
ATCATCACAT GGAACGAACT GTGTCATGTA GCAGAGACGA TGTCACGAGG CCTCTCATAC 
CTGCATGAGG ATGTGCCCTG GTGCCGTGGC GAGGGCCACA AGCCGTCTAT TGCCCACAGG 
GACTTTAAAA GTAAGAATGT ATTGCTGAAG AGCGACCTCA CAGCCGTGCT GGCTGACTTT 
GGCTTGGCTG TTCGATTTGA GCCAGGGAAA CCTCCAGGGG ACACCCACGG ACAGGTAGGC 
ACGAGACGGT ACATGGCTCC TGAGGTGCTC GAGGGAGCCA TCAACTTCCA GAGAGATGCC 
TTCCTGCGCA TTGACATGTA TGCCATGGGG TTGGTGCTGT GGGAGCTTGT GTCTCGCTGC 
AAGGCTGCAG ACGGACCCGT GGATGAGTAC ATGCTGCCCT TTGAGGAAGA GATTGGCCAG 
CACCCTTCGT TGGAGGAGCT GCAGGAGGTG GTGGTGCACA AGAAGATGAG GCCCACCATT 
AAAGATCACT GGTTGAAACA CCCGGGCCTG GCCCAGCTTT GTGTGACCAT CGAGGAGTGC 
TGGGACCATG ATGCAGAGGC TCGCTTGTCC GCGGGCTGTG TGGAGGAGCG GGTGTCCCTG 
ATTCGGAGGT CGGTCAACGG CACTACCTCG GACTGTCTCG TTTCCCTGGT GACCTCTGTC 
ACCAATGTGG ACCTGCCCCC TAAAGAGTCA AGCATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_005265583.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265640.1 Homo sapiens activin A receptor, type IIB (ACVR2B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu37602
Clone ID Related Accession (Same CDS sequence)	XM_005265583.2 , XM_005265583.3
Accession Version	XM_005265583.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	activin receptor type-2B isoform X1
Comment

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGTGGGC AGCCTCTCCC CAAAGGCTCT 
GGGCGTGGGG AGGCTGAGAC ACGGGAGTGC ATCTACTACA ACGCCAACTG GGAGCTGGAG 
CGCACCAACC AGAGCGGCCT GGAGCGCTGC GAAGGCGAGC AGGACAAGCG GCTGCACTGC 
TACGCCTCCT GGCGCAACAG CTCTGGCACC ATCGAGCTCG TGAAGAAGGG CTGCTGGCTA 
GATGACTTCA ACTGCTACGA TAGGCAGGAG TGTGTGGCCA CTGAGGAGAA CCCCCAGGTG 
TACTTCTGCT GCTGTGAAGG CAACTTCTGC AACGAACGCT TCACTCATTT GCCAGAGGCT 
GGGGGCCCGG AAGTCACGTA CGAGCCACCC CCGACAGCCC CCACCCTGCT CACGGTGCTG 
GCCTACTCAC TGCTGCCCAT CGGGGGCCTT TCCCTCATCG TCCTGCTGGC CTTTTGGATG 
TACCGGCATC GCAAGCCCCC CTACGGTCAT GTGGACATCC ATGAGGACCC TGGGCCTCCA 
CCACCATCCC CTCTGGTGGG CCTGAAGCCA CTGCAGCTGC TGGAGATCAA GGCTCGGGGG 
CGCTTTGGCT GTGTCTGGAA GGCCCAGCTC ATGAATGACT TTGTAGCTGT CAAGATCTTC 
CCACTCCAGG ACAAGCAGTC GTGGCAGAGT GAACGGGAGA TCTTCAGCAC ACCTGGCATG 
AAGCACGAGA ACCTGCTACA GTTCATTGCT GCCGAGAAGC GAGGCTCCAA CCTCGAAGTA 
GAGCTGTGGC TCATCACGGC CTTCCATGAC AAGGGCTCCC TCACGGATTA CCTCAAGGGG 
AACATCATCA CATGGAACGA ACTGTGTCAT GTAGCAGAGA CGATGTCACG AGGCCTCTCA 
TACCTGCATG AGGATGTGCC CTGGTGCCGT GGCGAGGGCC ACAAGCCGTC TATTGCCCAC 
AGGGACTTTA AAAGTAAGAA TGTATTGCTG AAGAGCGACC TCACAGCCGT GCTGGCTGAC 
TTTGGCTTGG CTGTTCGATT TGAGCCAGGG AAACCTCCAG GGGACACCCA CGGACAGGTA 
GGCACGAGAC GGTACATGGC TCCTGAGGTG CTCGAGGGAG CCATCAACTT CCAGAGAGAT 
GCCTTCCTGC GCATTGACAT GTATGCCATG GGGTTGGTGC TGTGGGAGCT TGTGTCTCGC 
TGCAAGGCTG CAGACGGACC CGTGGATGAG TACATGCTGC CCTTTGAGGA AGAGATTGGC 
CAGCACCCTT CGTTGGAGGA GCTGCAGGAG GTGGTGGTGC ACAAGAAGAT GAGGCCCACC 
ATTAAAGATC ACTGGTTGAA ACACCCGGGC CTGGCCCAGC TTTGTGTGAC CATCGAGGAG 
TGCTGGGACC ATGATGCAGA GGCTCGCTTG TCCGCGGGCT GTGTGGAGGA GCGGGTGTCC 
CTGATTCGGA GGTCGGTCAA CGGCACTACC TCGGACTGTC TCGTTTCCCT GGTGACCTCT 
GTCACCAATG TGGACCTGCC CCCTAAAGAG TCAAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

XP_005265640.1

Translation

MPLPLSGPAMWRSGEPQRLWAWSPQAGDTRAGGQPLPKGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_005265583.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens activin A receptor, type IIB (ACVR2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265583.2

ORF Insert Sequence:

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGTGGGC AGCCTCTCCC CAAAGGCTCT 
GGGCGTGGGG AGGCTGAGAC ACGGGAGTGC ATCTACTACA ACGCCAACTG GGAGCTGGAG 
CGCACCAACC AGAGCGGCCT GGAGCGCTGC GAAGGCGAGC AGGACAAGCG GCTGCACTGC 
TACGCCTCCT GGCGCAACAG CTCTGGCACC ATCGAGCTCG TGAAGAAGGG CTGCTGGCTA 
GATGACTTCA ACTGCTACGA TAGGCAGGAG TGTGTGGCCA CTGAGGAGAA CCCCCAGGTG 
TACTTCTGCT GCTGTGAAGG CAACTTCTGC AACGAACGCT TCACTCATTT GCCAGAGGCT 
GGGGGCCCGG AAGTCACGTA CGAGCCACCC CCGACAGCCC CCACCCTGCT CACGGTGCTG 
GCCTACTCAC TGCTGCCCAT CGGGGGCCTT TCCCTCATCG TCCTGCTGGC CTTTTGGATG 
TACCGGCATC GCAAGCCCCC CTACGGTCAT GTGGACATCC ATGAGGACCC TGGGCCTCCA 
CCACCATCCC CTCTGGTGGG CCTGAAGCCA CTGCAGCTGC TGGAGATCAA GGCTCGGGGG 
CGCTTTGGCT GTGTCTGGAA GGCCCAGCTC ATGAATGACT TTGTAGCTGT CAAGATCTTC 
CCACTCCAGG ACAAGCAGTC GTGGCAGAGT GAACGGGAGA TCTTCAGCAC ACCTGGCATG 
AAGCACGAGA ACCTGCTACA GTTCATTGCT GCCGAGAAGC GAGGCTCCAA CCTCGAAGTA 
GAGCTGTGGC TCATCACGGC CTTCCATGAC AAGGGCTCCC TCACGGATTA CCTCAAGGGG 
AACATCATCA CATGGAACGA ACTGTGTCAT GTAGCAGAGA CGATGTCACG AGGCCTCTCA 
TACCTGCATG AGGATGTGCC CTGGTGCCGT GGCGAGGGCC ACAAGCCGTC TATTGCCCAC 
AGGGACTTTA AAAGTAAGAA TGTATTGCTG AAGAGCGACC TCACAGCCGT GCTGGCTGAC 
TTTGGCTTGG CTGTTCGATT TGAGCCAGGG AAACCTCCAG GGGACACCCA CGGACAGGTA 
GGCACGAGAC GGTACATGGC TCCTGAGGTG CTCGAGGGAG CCATCAACTT CCAGAGAGAT 
GCCTTCCTGC GCATTGACAT GTATGCCATG GGGTTGGTGC TGTGGGAGCT TGTGTCTCGC 
TGCAAGGCTG CAGACGGACC CGTGGATGAG TACATGCTGC CCTTTGAGGA AGAGATTGGC 
CAGCACCCTT CGTTGGAGGA GCTGCAGGAG GTGGTGGTGC ACAAGAAGAT GAGGCCCACC 
ATTAAAGATC ACTGGTTGAA ACACCCGGGC CTGGCCCAGC TTTGTGTGAC CATCGAGGAG 
TGCTGGGACC ATGATGCAGA GGCTCGCTTG TCCGCGGGCT GTGTGGAGGA GCGGGTGTCC 
CTGATTCGGA GGTCGGTCAA CGGCACTACC TCGGACTGTC TCGTTTCCCT GGTGACCTCT 
GTCACCAATG TGGACCTGCC CCCTAAAGAG TCAAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_005265583.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265640.1 Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu37602
Clone ID Related Accession (Same CDS sequence)	XM_005265583.2 , XM_005265583.3
Accession Version	XM_005265583.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activin receptor type-2B isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005265583.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGTGGGC AGCCTCTCCC CAAAGGCTCT 
GGGCGTGGGG AGGCTGAGAC ACGGGAGTGC ATCTACTACA ACGCCAACTG GGAGCTGGAG 
CGCACCAACC AGAGCGGCCT GGAGCGCTGC GAAGGCGAGC AGGACAAGCG GCTGCACTGC 
TACGCCTCCT GGCGCAACAG CTCTGGCACC ATCGAGCTCG TGAAGAAGGG CTGCTGGCTA 
GATGACTTCA ACTGCTACGA TAGGCAGGAG TGTGTGGCCA CTGAGGAGAA CCCCCAGGTG 
TACTTCTGCT GCTGTGAAGG CAACTTCTGC AACGAACGCT TCACTCATTT GCCAGAGGCT 
GGGGGCCCGG AAGTCACGTA CGAGCCACCC CCGACAGCCC CCACCCTGCT CACGGTGCTG 
GCCTACTCAC TGCTGCCCAT CGGGGGCCTT TCCCTCATCG TCCTGCTGGC CTTTTGGATG 
TACCGGCATC GCAAGCCCCC CTACGGTCAT GTGGACATCC ATGAGGACCC TGGGCCTCCA 
CCACCATCCC CTCTGGTGGG CCTGAAGCCA CTGCAGCTGC TGGAGATCAA GGCTCGGGGG 
CGCTTTGGCT GTGTCTGGAA GGCCCAGCTC ATGAATGACT TTGTAGCTGT CAAGATCTTC 
CCACTCCAGG ACAAGCAGTC GTGGCAGAGT GAACGGGAGA TCTTCAGCAC ACCTGGCATG 
AAGCACGAGA ACCTGCTACA GTTCATTGCT GCCGAGAAGC GAGGCTCCAA CCTCGAAGTA 
GAGCTGTGGC TCATCACGGC CTTCCATGAC AAGGGCTCCC TCACGGATTA CCTCAAGGGG 
AACATCATCA CATGGAACGA ACTGTGTCAT GTAGCAGAGA CGATGTCACG AGGCCTCTCA 
TACCTGCATG AGGATGTGCC CTGGTGCCGT GGCGAGGGCC ACAAGCCGTC TATTGCCCAC 
AGGGACTTTA AAAGTAAGAA TGTATTGCTG AAGAGCGACC TCACAGCCGT GCTGGCTGAC 
TTTGGCTTGG CTGTTCGATT TGAGCCAGGG AAACCTCCAG GGGACACCCA CGGACAGGTA 
GGCACGAGAC GGTACATGGC TCCTGAGGTG CTCGAGGGAG CCATCAACTT CCAGAGAGAT 
GCCTTCCTGC GCATTGACAT GTATGCCATG GGGTTGGTGC TGTGGGAGCT TGTGTCTCGC 
TGCAAGGCTG CAGACGGACC CGTGGATGAG TACATGCTGC CCTTTGAGGA AGAGATTGGC 
CAGCACCCTT CGTTGGAGGA GCTGCAGGAG GTGGTGGTGC ACAAGAAGAT GAGGCCCACC 
ATTAAAGATC ACTGGTTGAA ACACCCGGGC CTGGCCCAGC TTTGTGTGAC CATCGAGGAG 
TGCTGGGACC ATGATGCAGA GGCTCGCTTG TCCGCGGGCT GTGTGGAGGA GCGGGTGTCC 
CTGATTCGGA GGTCGGTCAA CGGCACTACC TCGGACTGTC TCGTTTCCCT GGTGACCTCT 
GTCACCAATG TGGACCTGCC CCCTAAAGAG TCAAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265640.1
CDS	2424..4025
Translation	MPLPLSGPAMWRSGEPQRLWAWSPQAGDTRAGGQPLPKGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_005265583.3
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265583.3

ORF Insert Sequence:

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGTGGGC AGCCTCTCCC CAAAGGCTCT 
GGGCGTGGGG AGGCTGAGAC ACGGGAGTGC ATCTACTACA ACGCCAACTG GGAGCTGGAG 
CGCACCAACC AGAGCGGCCT GGAGCGCTGC GAAGGCGAGC AGGACAAGCG GCTGCACTGC 
TACGCCTCCT GGCGCAACAG CTCTGGCACC ATCGAGCTCG TGAAGAAGGG CTGCTGGCTA 
GATGACTTCA ACTGCTACGA TAGGCAGGAG TGTGTGGCCA CTGAGGAGAA CCCCCAGGTG 
TACTTCTGCT GCTGTGAAGG CAACTTCTGC AACGAACGCT TCACTCATTT GCCAGAGGCT 
GGGGGCCCGG AAGTCACGTA CGAGCCACCC CCGACAGCCC CCACCCTGCT CACGGTGCTG 
GCCTACTCAC TGCTGCCCAT CGGGGGCCTT TCCCTCATCG TCCTGCTGGC CTTTTGGATG 
TACCGGCATC GCAAGCCCCC CTACGGTCAT GTGGACATCC ATGAGGACCC TGGGCCTCCA 
CCACCATCCC CTCTGGTGGG CCTGAAGCCA CTGCAGCTGC TGGAGATCAA GGCTCGGGGG 
CGCTTTGGCT GTGTCTGGAA GGCCCAGCTC ATGAATGACT TTGTAGCTGT CAAGATCTTC 
CCACTCCAGG ACAAGCAGTC GTGGCAGAGT GAACGGGAGA TCTTCAGCAC ACCTGGCATG 
AAGCACGAGA ACCTGCTACA GTTCATTGCT GCCGAGAAGC GAGGCTCCAA CCTCGAAGTA 
GAGCTGTGGC TCATCACGGC CTTCCATGAC AAGGGCTCCC TCACGGATTA CCTCAAGGGG 
AACATCATCA CATGGAACGA ACTGTGTCAT GTAGCAGAGA CGATGTCACG AGGCCTCTCA 
TACCTGCATG AGGATGTGCC CTGGTGCCGT GGCGAGGGCC ACAAGCCGTC TATTGCCCAC 
AGGGACTTTA AAAGTAAGAA TGTATTGCTG AAGAGCGACC TCACAGCCGT GCTGGCTGAC 
TTTGGCTTGG CTGTTCGATT TGAGCCAGGG AAACCTCCAG GGGACACCCA CGGACAGGTA 
GGCACGAGAC GGTACATGGC TCCTGAGGTG CTCGAGGGAG CCATCAACTT CCAGAGAGAT 
GCCTTCCTGC GCATTGACAT GTATGCCATG GGGTTGGTGC TGTGGGAGCT TGTGTCTCGC 
TGCAAGGCTG CAGACGGACC CGTGGATGAG TACATGCTGC CCTTTGAGGA AGAGATTGGC 
CAGCACCCTT CGTTGGAGGA GCTGCAGGAG GTGGTGGTGC ACAAGAAGAT GAGGCCCACC 
ATTAAAGATC ACTGGTTGAA ACACCCGGGC CTGGCCCAGC TTTGTGTGAC CATCGAGGAG 
TGCTGGGACC ATGATGCAGA GGCTCGCTTG TCCGCGGGCT GTGTGGAGGA GCGGGTGTCC 
CTGATTCGGA GGTCGGTCAA CGGCACTACC TCGGACTGTC TCGTTTCCCT GGTGACCTCT 
GTCACCAATG TGGACCTGCC CCCTAAAGAG TCAAGCATCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_017007514.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863003.1 Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu94785
Clone ID Related Accession (Same CDS sequence)	XM_017007514.1
Accession Version	XM_017007514.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activin receptor type-2B isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGCTCTG GGCGTGGGGA GGCTGAGACA 
CGGGAGTGCA TCTACTACAA CGCCAACTGG GAGCTGGAGC GCACCAACCA GAGCGGCCTG 
GAGCGCTGCG AAGGCGAGCA GGACAAGCGG CTGCACTGCT ACGCCTCCTG GCGCAACAGC 
TCTGGCACCA TCGAGCTCGT GAAGAAGGGC TGCTGGCTAG ATGACTTCAA CTGCTACGAT 
AGGCAGGAGT GTGTGGCCAC TGAGGAGAAC CCCCAGGTGT ACTTCTGCTG CTGTGAAGGC 
AACTTCTGCA ACGAACGCTT CACTCATTTG CCAGAGGCTG GGGGCCCGGA AGTCACGTAC 
GAGCCACCCC CGACAGCCCC CACCCTGCTC ACGGTGCTGG CCTACTCACT GCTGCCCATC 
GGGGGCCTTT CCCTCATCGT CCTGCTGGCC TTTTGGATGT ACCGGCATCG CAAGCCCCCC 
TACGGTCATG TGGACATCCA TGAGGACCCT GGGCCTCCAC CACCATCCCC TCTGGTGGGC 
CTGAAGCCAC TGCAGCTGCT GGAGATCAAG GCTCGGGGGC GCTTTGGCTG TGTCTGGAAG 
GCCCAGCTCA TGAATGACTT TGTAGCTGTC AAGATCTTCC CACTCCAGGA CAAGCAGTCG 
TGGCAGAGTG AACGGGAGAT CTTCAGCACA CCTGGCATGA AGCACGAGAA CCTGCTACAG 
TTCATTGCTG CCGAGAAGCG AGGCTCCAAC CTCGAAGTAG AGCTGTGGCT CATCACGGCC 
TTCCATGACA AGGGCTCCCT CACGGATTAC CTCAAGGGGA ACATCATCAC ATGGAACGAA 
CTGTGTCATG TAGCAGAGAC GATGTCACGA GGCCTCTCAT ACCTGCATGA GGATGTGCCC 
TGGTGCCGTG GCGAGGGCCA CAAGCCGTCT ATTGCCCACA GGGACTTTAA AAGTAAGAAT 
GTATTGCTGA AGAGCGACCT CACAGCCGTG CTGGCTGACT TTGGCTTGGC TGTTCGATTT 
GAGCCAGGGA AACCTCCAGG GGACACCCAC GGACAGGTAG GCACGAGACG GTACATGGCT 
CCTGAGGTGC TCGAGGGAGC CATCAACTTC CAGAGAGATG CCTTCCTGCG CATTGACATG 
TATGCCATGG GGTTGGTGCT GTGGGAGCTT GTGTCTCGCT GCAAGGCTGC AGACGGACCC 
GTGGATGAGT ACATGCTGCC CTTTGAGGAA GAGATTGGCC AGCACCCTTC GTTGGAGGAG 
CTGCAGGAGG TGGTGGTGCA CAAGAAGATG AGGCCCACCA TTAAAGATCA CTGGTTGAAA 
CACCCGGGCC TGGCCCAGCT TTGTGTGACC ATCGAGGAGT GCTGGGACCA TGATGCAGAG 
GCTCGCTTGT CCGCGGGCTG TGTGGAGGAG CGGGTGTCCC TGATTCGGAG GTCGGTCAAC 
GGCACTACCT CGGACTGTCT CGTTTCCCTG GTGACCTCTG TCACCAATGT GGACCTGCCC 
CCTAAAGAGT CAAGCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863003.1
CDS	2424..4004
Translation	MPLPLSGPAMWRSGEPQRLWAWSPQAGDTRAGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_017007514.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007514.1

ORF Insert Sequence:

ATGCCCCTTC CCCTGAGTGG ACCTGCCATG TGGCGCTCCG GGGAGCCGCA GAGGCTGTGG 
GCCTGGAGCC CCCAGGCCGG GGACACCAGG GCAGGCTCTG GGCGTGGGGA GGCTGAGACA 
CGGGAGTGCA TCTACTACAA CGCCAACTGG GAGCTGGAGC GCACCAACCA GAGCGGCCTG 
GAGCGCTGCG AAGGCGAGCA GGACAAGCGG CTGCACTGCT ACGCCTCCTG GCGCAACAGC 
TCTGGCACCA TCGAGCTCGT GAAGAAGGGC TGCTGGCTAG ATGACTTCAA CTGCTACGAT 
AGGCAGGAGT GTGTGGCCAC TGAGGAGAAC CCCCAGGTGT ACTTCTGCTG CTGTGAAGGC 
AACTTCTGCA ACGAACGCTT CACTCATTTG CCAGAGGCTG GGGGCCCGGA AGTCACGTAC 
GAGCCACCCC CGACAGCCCC CACCCTGCTC ACGGTGCTGG CCTACTCACT GCTGCCCATC 
GGGGGCCTTT CCCTCATCGT CCTGCTGGCC TTTTGGATGT ACCGGCATCG CAAGCCCCCC 
TACGGTCATG TGGACATCCA TGAGGACCCT GGGCCTCCAC CACCATCCCC TCTGGTGGGC 
CTGAAGCCAC TGCAGCTGCT GGAGATCAAG GCTCGGGGGC GCTTTGGCTG TGTCTGGAAG 
GCCCAGCTCA TGAATGACTT TGTAGCTGTC AAGATCTTCC CACTCCAGGA CAAGCAGTCG 
TGGCAGAGTG AACGGGAGAT CTTCAGCACA CCTGGCATGA AGCACGAGAA CCTGCTACAG 
TTCATTGCTG CCGAGAAGCG AGGCTCCAAC CTCGAAGTAG AGCTGTGGCT CATCACGGCC 
TTCCATGACA AGGGCTCCCT CACGGATTAC CTCAAGGGGA ACATCATCAC ATGGAACGAA 
CTGTGTCATG TAGCAGAGAC GATGTCACGA GGCCTCTCAT ACCTGCATGA GGATGTGCCC 
TGGTGCCGTG GCGAGGGCCA CAAGCCGTCT ATTGCCCACA GGGACTTTAA AAGTAAGAAT 
GTATTGCTGA AGAGCGACCT CACAGCCGTG CTGGCTGACT TTGGCTTGGC TGTTCGATTT 
GAGCCAGGGA AACCTCCAGG GGACACCCAC GGACAGGTAG GCACGAGACG GTACATGGCT 
CCTGAGGTGC TCGAGGGAGC CATCAACTTC CAGAGAGATG CCTTCCTGCG CATTGACATG 
TATGCCATGG GGTTGGTGCT GTGGGAGCTT GTGTCTCGCT GCAAGGCTGC AGACGGACCC 
GTGGATGAGT ACATGCTGCC CTTTGAGGAA GAGATTGGCC AGCACCCTTC GTTGGAGGAG 
CTGCAGGAGG TGGTGGTGCA CAAGAAGATG AGGCCCACCA TTAAAGATCA CTGGTTGAAA 
CACCCGGGCC TGGCCCAGCT TTGTGTGACC ATCGAGGAGT GCTGGGACCA TGATGCAGAG 
GCTCGCTTGT CCGCGGGCTG TGTGGAGGAG CGGGTGTCCC TGATTCGGAG GTCGGTCAAC 
GGCACTACCT CGGACTGTCT CGTTTCCCTG GTGACCTCTG TCACCAATGT GGACCTGCCC 
CCTAAAGAGT CAAGCATCTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_017007515.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863004.1 Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu94786
Clone ID Related Accession (Same CDS sequence)	XM_017007515.2 , XM_017007515.1
Accession Version	XM_017007515.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activin receptor type-2B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017007515.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGCCG GGACGCGGAG CCTCAGGGTC GGAGTTCGGG CTACGCGGGC GCGTGGAACC 
CAGGGAAAGA GCTCTGGGCG TGGGGAGGCT GAGACACGGG AGTGCATCTA CTACAACGCC 
AACTGGGAGC TGGAGCGCAC CAACCAGAGC GGCCTGGAGC GCTGCGAAGG CGAGCAGGAC 
AAGCGGCTGC ACTGCTACGC CTCCTGGCGC AACAGCTCTG GCACCATCGA GCTCGTGAAG 
AAGGGCTGCT GGCTAGATGA CTTCAACTGC TACGATAGGC AGGAGTGTGT GGCCACTGAG 
GAGAACCCCC AGGTGTACTT CTGCTGCTGT GAAGGCAACT TCTGCAACGA ACGCTTCACT 
CATTTGCCAG AGGCTGGGGG CCCGGAAGTC ACGTACGAGC CACCCCCGAC AGCCCCCACC 
CTGCTCACGG TGCTGGCCTA CTCACTGCTG CCCATCGGGG GCCTTTCCCT CATCGTCCTG 
CTGGCCTTTT GGATGTACCG GCATCGCAAG CCCCCCTACG GTCATGTGGA CATCCATGAG 
GACCCTGGGC CTCCACCACC ATCCCCTCTG GTGGGCCTGA AGCCACTGCA GCTGCTGGAG 
ATCAAGGCTC GGGGGCGCTT TGGCTGTGTC TGGAAGGCCC AGCTCATGAA TGACTTTGTA 
GCTGTCAAGA TCTTCCCACT CCAGGACAAG CAGTCGTGGC AGAGTGAACG GGAGATCTTC 
AGCACACCTG GCATGAAGCA CGAGAACCTG CTACAGTTCA TTGCTGCCGA GAAGCGAGGC 
TCCAACCTCG AAGTAGAGCT GTGGCTCATC ACGGCCTTCC ATGACAAGGG CTCCCTCACG 
GATTACCTCA AGGGGAACAT CATCACATGG AACGAACTGT GTCATGTAGC AGAGACGATG 
TCACGAGGCC TCTCATACCT GCATGAGGAT GTGCCCTGGT GCCGTGGCGA GGGCCACAAG 
CCGTCTATTG CCCACAGGGA CTTTAAAAGT AAGAATGTAT TGCTGAAGAG CGACCTCACA 
GCCGTGCTGG CTGACTTTGG CTTGGCTGTT CGATTTGAGC CAGGGAAACC TCCAGGGGAC 
ACCCACGGAC AGGTAGGCAC GAGACGGTAC ATGGCTCCTG AGGTGCTCGA GGGAGCCATC 
AACTTCCAGA GAGATGCCTT CCTGCGCATT GACATGTATG CCATGGGGTT GGTGCTGTGG 
GAGCTTGTGT CTCGCTGCAA GGCTGCAGAC GGACCCGTGG ATGAGTACAT GCTGCCCTTT 
GAGGAAGAGA TTGGCCAGCA CCCTTCGTTG GAGGAGCTGC AGGAGGTGGT GGTGCACAAG 
AAGATGAGGC CCACCATTAA AGATCACTGG TTGAAACACC CGGGCCTGGC CCAGCTTTGT 
GTGACCATCG AGGAGTGCTG GGACCATGAT GCAGAGGCTC GCTTGTCCGC GGGCTGTGTG 
GAGGAGCGGG TGTCCCTGAT TCGGAGGTCG GTCAACGGCA CTACCTCGGA CTGTCTCGTT 
TCCCTGGTGA CCTCTGTCAC CAATGTGGAC CTGCCCCCTA AAGAGTCAAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863004.1
CDS	226..1782
Translation	MGAGTRSLRVGVRATRARGTQGKSSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_017007515.2
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007515.2

ORF Insert Sequence:

ATGGGGGCCG GGACGCGGAG CCTCAGGGTC GGAGTTCGGG CTACGCGGGC GCGTGGAACC 
CAGGGAAAGA GCTCTGGGCG TGGGGAGGCT GAGACACGGG AGTGCATCTA CTACAACGCC 
AACTGGGAGC TGGAGCGCAC CAACCAGAGC GGCCTGGAGC GCTGCGAAGG CGAGCAGGAC 
AAGCGGCTGC ACTGCTACGC CTCCTGGCGC AACAGCTCTG GCACCATCGA GCTCGTGAAG 
AAGGGCTGCT GGCTAGATGA CTTCAACTGC TACGATAGGC AGGAGTGTGT GGCCACTGAG 
GAGAACCCCC AGGTGTACTT CTGCTGCTGT GAAGGCAACT TCTGCAACGA ACGCTTCACT 
CATTTGCCAG AGGCTGGGGG CCCGGAAGTC ACGTACGAGC CACCCCCGAC AGCCCCCACC 
CTGCTCACGG TGCTGGCCTA CTCACTGCTG CCCATCGGGG GCCTTTCCCT CATCGTCCTG 
CTGGCCTTTT GGATGTACCG GCATCGCAAG CCCCCCTACG GTCATGTGGA CATCCATGAG 
GACCCTGGGC CTCCACCACC ATCCCCTCTG GTGGGCCTGA AGCCACTGCA GCTGCTGGAG 
ATCAAGGCTC GGGGGCGCTT TGGCTGTGTC TGGAAGGCCC AGCTCATGAA TGACTTTGTA 
GCTGTCAAGA TCTTCCCACT CCAGGACAAG CAGTCGTGGC AGAGTGAACG GGAGATCTTC 
AGCACACCTG GCATGAAGCA CGAGAACCTG CTACAGTTCA TTGCTGCCGA GAAGCGAGGC 
TCCAACCTCG AAGTAGAGCT GTGGCTCATC ACGGCCTTCC ATGACAAGGG CTCCCTCACG 
GATTACCTCA AGGGGAACAT CATCACATGG AACGAACTGT GTCATGTAGC AGAGACGATG 
TCACGAGGCC TCTCATACCT GCATGAGGAT GTGCCCTGGT GCCGTGGCGA GGGCCACAAG 
CCGTCTATTG CCCACAGGGA CTTTAAAAGT AAGAATGTAT TGCTGAAGAG CGACCTCACA 
GCCGTGCTGG CTGACTTTGG CTTGGCTGTT CGATTTGAGC CAGGGAAACC TCCAGGGGAC 
ACCCACGGAC AGGTAGGCAC GAGACGGTAC ATGGCTCCTG AGGTGCTCGA GGGAGCCATC 
AACTTCCAGA GAGATGCCTT CCTGCGCATT GACATGTATG CCATGGGGTT GGTGCTGTGG 
GAGCTTGTGT CTCGCTGCAA GGCTGCAGAC GGACCCGTGG ATGAGTACAT GCTGCCCTTT 
GAGGAAGAGA TTGGCCAGCA CCCTTCGTTG GAGGAGCTGC AGGAGGTGGT GGTGCACAAG 
AAGATGAGGC CCACCATTAA AGATCACTGG TTGAAACACC CGGGCCTGGC CCAGCTTTGT 
GTGACCATCG AGGAGTGCTG GGACCATGAT GCAGAGGCTC GCTTGTCCGC GGGCTGTGTG 
GAGGAGCGGG TGTCCCTGAT TCGGAGGTCG GTCAACGGCA CTACCTCGGA CTGTCTCGTT 
TCCCTGGTGA CCTCTGTCAC CAATGTGGAC CTGCCCCCTA AAGAGTCAAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_017007515.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863004.1 Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.

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CloneID	OHu94786
Clone ID Related Accession (Same CDS sequence)	XM_017007515.2 , XM_017007515.1
Accession Version	XM_017007515.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1557bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	activin receptor type-2B isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGGGGCCG GGACGCGGAG CCTCAGGGTC GGAGTTCGGG CTACGCGGGC GCGTGGAACC 
CAGGGAAAGA GCTCTGGGCG TGGGGAGGCT GAGACACGGG AGTGCATCTA CTACAACGCC 
AACTGGGAGC TGGAGCGCAC CAACCAGAGC GGCCTGGAGC GCTGCGAAGG CGAGCAGGAC 
AAGCGGCTGC ACTGCTACGC CTCCTGGCGC AACAGCTCTG GCACCATCGA GCTCGTGAAG 
AAGGGCTGCT GGCTAGATGA CTTCAACTGC TACGATAGGC AGGAGTGTGT GGCCACTGAG 
GAGAACCCCC AGGTGTACTT CTGCTGCTGT GAAGGCAACT TCTGCAACGA ACGCTTCACT 
CATTTGCCAG AGGCTGGGGG CCCGGAAGTC ACGTACGAGC CACCCCCGAC AGCCCCCACC 
CTGCTCACGG TGCTGGCCTA CTCACTGCTG CCCATCGGGG GCCTTTCCCT CATCGTCCTG 
CTGGCCTTTT GGATGTACCG GCATCGCAAG CCCCCCTACG GTCATGTGGA CATCCATGAG 
GACCCTGGGC CTCCACCACC ATCCCCTCTG GTGGGCCTGA AGCCACTGCA GCTGCTGGAG 
ATCAAGGCTC GGGGGCGCTT TGGCTGTGTC TGGAAGGCCC AGCTCATGAA TGACTTTGTA 
GCTGTCAAGA TCTTCCCACT CCAGGACAAG CAGTCGTGGC AGAGTGAACG GGAGATCTTC 
AGCACACCTG GCATGAAGCA CGAGAACCTG CTACAGTTCA TTGCTGCCGA GAAGCGAGGC 
TCCAACCTCG AAGTAGAGCT GTGGCTCATC ACGGCCTTCC ATGACAAGGG CTCCCTCACG 
GATTACCTCA AGGGGAACAT CATCACATGG AACGAACTGT GTCATGTAGC AGAGACGATG 
TCACGAGGCC TCTCATACCT GCATGAGGAT GTGCCCTGGT GCCGTGGCGA GGGCCACAAG 
CCGTCTATTG CCCACAGGGA CTTTAAAAGT AAGAATGTAT TGCTGAAGAG CGACCTCACA 
GCCGTGCTGG CTGACTTTGG CTTGGCTGTT CGATTTGAGC CAGGGAAACC TCCAGGGGAC 
ACCCACGGAC AGGTAGGCAC GAGACGGTAC ATGGCTCCTG AGGTGCTCGA GGGAGCCATC 
AACTTCCAGA GAGATGCCTT CCTGCGCATT GACATGTATG CCATGGGGTT GGTGCTGTGG 
GAGCTTGTGT CTCGCTGCAA GGCTGCAGAC GGACCCGTGG ATGAGTACAT GCTGCCCTTT 
GAGGAAGAGA TTGGCCAGCA CCCTTCGTTG GAGGAGCTGC AGGAGGTGGT GGTGCACAAG 
AAGATGAGGC CCACCATTAA AGATCACTGG TTGAAACACC CGGGCCTGGC CCAGCTTTGT 
GTGACCATCG AGGAGTGCTG GGACCATGAT GCAGAGGCTC GCTTGTCCGC GGGCTGTGTG 
GAGGAGCGGG TGTCCCTGAT TCGGAGGTCG GTCAACGGCA CTACCTCGGA CTGTCTCGTT 
TCCCTGGTGA CCTCTGTCAC CAATGTGGAC CTGCCCCCTA AAGAGTCAAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863004.1
CDS	93..1649
Translation	MGAGTRSLRVGVRATRARGTQGKSSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_017007515.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007515.1

ORF Insert Sequence:

ATGGGGGCCG GGACGCGGAG CCTCAGGGTC GGAGTTCGGG CTACGCGGGC GCGTGGAACC 
CAGGGAAAGA GCTCTGGGCG TGGGGAGGCT GAGACACGGG AGTGCATCTA CTACAACGCC 
AACTGGGAGC TGGAGCGCAC CAACCAGAGC GGCCTGGAGC GCTGCGAAGG CGAGCAGGAC 
AAGCGGCTGC ACTGCTACGC CTCCTGGCGC AACAGCTCTG GCACCATCGA GCTCGTGAAG 
AAGGGCTGCT GGCTAGATGA CTTCAACTGC TACGATAGGC AGGAGTGTGT GGCCACTGAG 
GAGAACCCCC AGGTGTACTT CTGCTGCTGT GAAGGCAACT TCTGCAACGA ACGCTTCACT 
CATTTGCCAG AGGCTGGGGG CCCGGAAGTC ACGTACGAGC CACCCCCGAC AGCCCCCACC 
CTGCTCACGG TGCTGGCCTA CTCACTGCTG CCCATCGGGG GCCTTTCCCT CATCGTCCTG 
CTGGCCTTTT GGATGTACCG GCATCGCAAG CCCCCCTACG GTCATGTGGA CATCCATGAG 
GACCCTGGGC CTCCACCACC ATCCCCTCTG GTGGGCCTGA AGCCACTGCA GCTGCTGGAG 
ATCAAGGCTC GGGGGCGCTT TGGCTGTGTC TGGAAGGCCC AGCTCATGAA TGACTTTGTA 
GCTGTCAAGA TCTTCCCACT CCAGGACAAG CAGTCGTGGC AGAGTGAACG GGAGATCTTC 
AGCACACCTG GCATGAAGCA CGAGAACCTG CTACAGTTCA TTGCTGCCGA GAAGCGAGGC 
TCCAACCTCG AAGTAGAGCT GTGGCTCATC ACGGCCTTCC ATGACAAGGG CTCCCTCACG 
GATTACCTCA AGGGGAACAT CATCACATGG AACGAACTGT GTCATGTAGC AGAGACGATG 
TCACGAGGCC TCTCATACCT GCATGAGGAT GTGCCCTGGT GCCGTGGCGA GGGCCACAAG 
CCGTCTATTG CCCACAGGGA CTTTAAAAGT AAGAATGTAT TGCTGAAGAG CGACCTCACA 
GCCGTGCTGG CTGACTTTGG CTTGGCTGTT CGATTTGAGC CAGGGAAACC TCCAGGGGAC 
ACCCACGGAC AGGTAGGCAC GAGACGGTAC ATGGCTCCTG AGGTGCTCGA GGGAGCCATC 
AACTTCCAGA GAGATGCCTT CCTGCGCATT GACATGTATG CCATGGGGTT GGTGCTGTGG 
GAGCTTGTGT CTCGCTGCAA GGCTGCAGAC GGACCCGTGG ATGAGTACAT GCTGCCCTTT 
GAGGAAGAGA TTGGCCAGCA CCCTTCGTTG GAGGAGCTGC AGGAGGTGGT GGTGCACAAG 
AAGATGAGGC CCACCATTAA AGATCACTGG TTGAAACACC CGGGCCTGGC CCAGCTTTGT 
GTGACCATCG AGGAGTGCTG GGACCATGAT GCAGAGGCTC GCTTGTCCGC GGGCTGTGTG 
GAGGAGCGGG TGTCCCTGAT TCGGAGGTCG GTCAACGGCA CTACCTCGGA CTGTCTCGTT 
TCCCTGGTGA CCTCTGTCAC CAATGTGGAC CTGCCCCCTA AAGAGTCAAG CATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ACVR2B ( XM_017007516.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016863005.1 Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X4, mRNA.

Price & Availability↑

CloneID	OHu94787
Clone ID Related Accession (Same CDS sequence)	XM_017007516.1
Accession Version	XM_017007516.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1536bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	activin receptor type-2B isoform X4
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATGGCAT TGCTGAGATC AACAAACATA AATAACCTGA GTCCAGTAGG CTCTGGGCGT 
GGGGAGGCTG AGACACGGGA GTGCATCTAC TACAACGCCA ACTGGGAGCT GGAGCGCACC 
AACCAGAGCG GCCTGGAGCG CTGCGAAGGC GAGCAGGACA AGCGGCTGCA CTGCTACGCC 
TCCTGGCGCA ACAGCTCTGG CACCATCGAG CTCGTGAAGA AGGGCTGCTG GCTAGATGAC 
TTCAACTGCT ACGATAGGCA GGAGTGTGTG GCCACTGAGG AGAACCCCCA GGTGTACTTC 
TGCTGCTGTG AAGGCAACTT CTGCAACGAA CGCTTCACTC ATTTGCCAGA GGCTGGGGGC 
CCGGAAGTCA CGTACGAGCC ACCCCCGACA GCCCCCACCC TGCTCACGGT GCTGGCCTAC 
TCACTGCTGC CCATCGGGGG CCTTTCCCTC ATCGTCCTGC TGGCCTTTTG GATGTACCGG 
CATCGCAAGC CCCCCTACGG TCATGTGGAC ATCCATGAGG ACCCTGGGCC TCCACCACCA 
TCCCCTCTGG TGGGCCTGAA GCCACTGCAG CTGCTGGAGA TCAAGGCTCG GGGGCGCTTT 
GGCTGTGTCT GGAAGGCCCA GCTCATGAAT GACTTTGTAG CTGTCAAGAT CTTCCCACTC 
CAGGACAAGC AGTCGTGGCA GAGTGAACGG GAGATCTTCA GCACACCTGG CATGAAGCAC 
GAGAACCTGC TACAGTTCAT TGCTGCCGAG AAGCGAGGCT CCAACCTCGA AGTAGAGCTG 
TGGCTCATCA CGGCCTTCCA TGACAAGGGC TCCCTCACGG ATTACCTCAA GGGGAACATC 
ATCACATGGA ACGAACTGTG TCATGTAGCA GAGACGATGT CACGAGGCCT CTCATACCTG 
CATGAGGATG TGCCCTGGTG CCGTGGCGAG GGCCACAAGC CGTCTATTGC CCACAGGGAC 
TTTAAAAGTA AGAATGTATT GCTGAAGAGC GACCTCACAG CCGTGCTGGC TGACTTTGGC 
TTGGCTGTTC GATTTGAGCC AGGGAAACCT CCAGGGGACA CCCACGGACA GGTAGGCACG 
AGACGGTACA TGGCTCCTGA GGTGCTCGAG GGAGCCATCA ACTTCCAGAG AGATGCCTTC 
CTGCGCATTG ACATGTATGC CATGGGGTTG GTGCTGTGGG AGCTTGTGTC TCGCTGCAAG 
GCTGCAGACG GACCCGTGGA TGAGTACATG CTGCCCTTTG AGGAAGAGAT TGGCCAGCAC 
CCTTCGTTGG AGGAGCTGCA GGAGGTGGTG GTGCACAAGA AGATGAGGCC CACCATTAAA 
GATCACTGGT TGAAACACCC GGGCCTGGCC CAGCTTTGTG TGACCATCGA GGAGTGCTGG 
GACCATGATG CAGAGGCTCG CTTGTCCGCG GGCTGTGTGG AGGAGCGGGT GTCCCTGATT 
CGGAGGTCGG TCAACGGCAC TACCTCGGAC TGTCTCGTTT CCCTGGTGAC CTCTGTCACC 
AATGTGGACC TGCCCCCTAA AGAGTCAAGC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863005.1
CDS	3438..4973
Translation	MMALLRSTNINNLSPVGSGRGEAETRECIYYNANWELERTNQSGLERCEGEQDKRLHCYASWRNSSGTIELVKKGCWLDDFNCYDRQECVATEENPQVYFCCCEGNFCNERFTHLPEAGGPEVTYEPPPTAPTLLTVLAYSLLPIGGLSLIVLLAFWMYRHRKPPYGHVDIHEDPGPPPPSPLVGLKPLQLLEIKARGRFGCVWKAQLMNDFVAVKIFPLQDKQSWQSEREIFSTPGMKHENLLQFIAAEKRGSNLEVELWLITAFHDKGSLTDYLKGNIITWNELCHVAETMSRGLSYLHEDVPWCRGEGHKPSIAHRDFKSKNVLLKSDLTAVLADFGLAVRFEPGKPPGDTHGQVGTRRYMAPEVLEGAINFQRDAFLRIDMYAMGLVLWELVSRCKAADGPVDEYMLPFEEEIGQHPSLEELQEVVVHKKMRPTIKDHWLKHPGLAQLCVTIEECWDHDAEARLSAGCVEERVSLIRRSVNGTTSDCLVSLVTSVTNVDLPPKESSI

Target ORF information:

RefSeq Version	XM_017007516.1
Organism	Homo sapiens(human)
Definition	Homo sapiens activin A receptor type 2B (ACVR2B), transcript variant X4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007516.1

ORF Insert Sequence:

ATGATGGCAT TGCTGAGATC AACAAACATA AATAACCTGA GTCCAGTAGG CTCTGGGCGT 
GGGGAGGCTG AGACACGGGA GTGCATCTAC TACAACGCCA ACTGGGAGCT GGAGCGCACC 
AACCAGAGCG GCCTGGAGCG CTGCGAAGGC GAGCAGGACA AGCGGCTGCA CTGCTACGCC 
TCCTGGCGCA ACAGCTCTGG CACCATCGAG CTCGTGAAGA AGGGCTGCTG GCTAGATGAC 
TTCAACTGCT ACGATAGGCA GGAGTGTGTG GCCACTGAGG AGAACCCCCA GGTGTACTTC 
TGCTGCTGTG AAGGCAACTT CTGCAACGAA CGCTTCACTC ATTTGCCAGA GGCTGGGGGC 
CCGGAAGTCA CGTACGAGCC ACCCCCGACA GCCCCCACCC TGCTCACGGT GCTGGCCTAC 
TCACTGCTGC CCATCGGGGG CCTTTCCCTC ATCGTCCTGC TGGCCTTTTG GATGTACCGG 
CATCGCAAGC CCCCCTACGG TCATGTGGAC ATCCATGAGG ACCCTGGGCC TCCACCACCA 
TCCCCTCTGG TGGGCCTGAA GCCACTGCAG CTGCTGGAGA TCAAGGCTCG GGGGCGCTTT 
GGCTGTGTCT GGAAGGCCCA GCTCATGAAT GACTTTGTAG CTGTCAAGAT CTTCCCACTC 
CAGGACAAGC AGTCGTGGCA GAGTGAACGG GAGATCTTCA GCACACCTGG CATGAAGCAC 
GAGAACCTGC TACAGTTCAT TGCTGCCGAG AAGCGAGGCT CCAACCTCGA AGTAGAGCTG 
TGGCTCATCA CGGCCTTCCA TGACAAGGGC TCCCTCACGG ATTACCTCAA GGGGAACATC 
ATCACATGGA ACGAACTGTG TCATGTAGCA GAGACGATGT CACGAGGCCT CTCATACCTG 
CATGAGGATG TGCCCTGGTG CCGTGGCGAG GGCCACAAGC CGTCTATTGC CCACAGGGAC 
TTTAAAAGTA AGAATGTATT GCTGAAGAGC GACCTCACAG CCGTGCTGGC TGACTTTGGC 
TTGGCTGTTC GATTTGAGCC AGGGAAACCT CCAGGGGACA CCCACGGACA GGTAGGCACG 
AGACGGTACA TGGCTCCTGA GGTGCTCGAG GGAGCCATCA ACTTCCAGAG AGATGCCTTC 
CTGCGCATTG ACATGTATGC CATGGGGTTG GTGCTGTGGG AGCTTGTGTC TCGCTGCAAG 
GCTGCAGACG GACCCGTGGA TGAGTACATG CTGCCCTTTG AGGAAGAGAT TGGCCAGCAC 
CCTTCGTTGG AGGAGCTGCA GGAGGTGGTG GTGCACAAGA AGATGAGGCC CACCATTAAA 
GATCACTGGT TGAAACACCC GGGCCTGGCC CAGCTTTGTG TGACCATCGA GGAGTGCTGG 
GACCATGATG CAGAGGCTCG CTTGTCCGCG GGCTGTGTGG AGGAGCGGGT GTCCCTGATT 
CGGAGGTCGG TCAACGGCAC TACCTCGGAC TGTCTCGTTT CCCTGGTGAC CTCTGTCACC 
AATGTGGACC TGCCCCCTAA AGAGTCAAGC ATCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.
Protein & cell8(1)39-54(2017 Jan)
Cassar L,Nicholls C,Pinto AR,Chen R,Wang L,Li H,Liu JP

Genetic Variant in ACVR2B Is Associated with Lean Mass.
Medicine and science in sports and exercise48(7)1270-5(2016 07)
Klimentidis YC,Bea JW,Thompson P,Klimecki WT,Hu C,Wu G,Nicholas JS,Ryckman KK,Chen Z

NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients.
Asian journal of andrology17(6)996-1005(2015 Nov-Dec)
Tian RH,Yang S,Zhu ZJ,Wang JL,Liu Y,Yao C,Ma M,Guo Y,Yuan Q,Hai Y,Huang YR,He Z,Li Z

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ACVR2B cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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