Gene Symbol | ARHGEF2 |
Entrez Gene ID | 9181 |
Full Name | Rho/Rac guanine nucleotide exchange factor 2 |
Synonyms | GEF,GEF-H1,GEFH1,LFP40,NEDMHM,P40 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate rho-dependent signals. Alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Jun 2009]. |
Disorder MIM: | |
Disorder Html: | ?Neurodevelopmental disorder with midbrain and hindbrain malformations, 617523 (3) |