DCAF15 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	DCAF15
Entrez Gene ID	90379
Full Name	DDB1 and CUL4 associated factor 15
Synonyms	C19orf72
General protein information	Preferred Names DDB1 and CUL4 associated factor 15 Names DDB1- and CUL4-associated factor 15
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19p13.12

mRNA and Protein(s)

mRNA	Protein	Name
NM_138353.2	NP_612362.2	DDB1- and CUL4-associated factor 15
NM_138353.3	NP_612362.2	DDB1- and CUL4-associated factor 15

Pathways from BioSystems

Homologies

Homo sapiens (human)	DCAF15	NP_612362.2
Pan troglodytes (chimpanzee)	DCAF15	XP_524449.4
Rattus norvegicus (Norway rat)	Dcaf15	NP_001100632.1
	DCAF15	XP_001111304.1
Bos taurus (cattle)	DCAF15	NP_001029857.1
Danio rerio (zebrafish)	dcaf15	XP_682800.2
Mus musculus (house mouse)	Dcaf15	NP_766090.2
Canis lupus familiaris (dog)	DCAF15	XP_003639829.1
Xenopus tropicalis (tropical clawed frog)	dcaf15	XP_004919204.1

Gene Ontology
Bibliography

Related articles in PubMed

Selective degradation of splicing factor CAPER? by anticancer sulfonamides.
Uehara T, Minoshima Y, Sagane K, Sugi NH, Mitsuhashi KO, Yamamoto N, Kamiyama H, Takahashi K, Kotake Y, Uesugi M, Yokoi A, Inoue A, Yoshida T, Mabuchi M, Tanaka A, Owa T
Nature chemical biology13(6)675-680(2017 Jun)

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
Han T, Goralski M, Gaskill N, Capota E, Kim J, Ting TC, Xie Y, Williams NS, Nijhawan D
Science (New York, N.Y.)356(6336)(2017 04)

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.
Jin J, Arias EE, Chen J, Harper JW, Walter JC
Molecular cell23(5)709-21(2006 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

DCAF15 expression may be a useful biomarker to guide clinical trials of splicing inhibitor sulfonamides(SPLAMs).
Title: Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

The following DCAF15 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DCAF15 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu06074	NM_138353.3 Latest version!	Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$249.50-$349.30 $499.00
View Old Accession Versions >>
OHu06074	NM_138353.2	Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$249.50-$349.30 $499.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

DCAF15 ( NM_138353.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_612362.2 Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.

Price & Availability↑

CloneID	OHu06074
Clone ID Related Accession (Same CDS sequence)	NM_138353.2 , NM_138353.3
Accession Version	NM_138353.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	DDB1- and CUL4-associated factor 15
Comment

ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC 
GGGGGAGCCG GAGGGAAGCG GGCAGCAGGG CGGCGGCGGG AGCACGTCCT CAAGCAGCTG 
GAGCGGGTCA AGATCAGCGG ACAGCTCTCC CCTCGCCTCT TCCGGAAGCT GCCTCCCCGG 
GTGTGCGTGT CCCTCAAGAA CATTGTGGAT GAGGACTTCC TCTATGCAGG ACATATCTTC 
CTGGGCTTTT CCAAATGCGG CCGCTACGTC CTCTCCTACA CCAGCAGCAG TGGGGATGAC 
GACTTCTCCT TCTACATCTA CCATCTGTAC TGGTGGGAGT TCAACGTTCA CAGCAAGCTC 
AAGCTGGTCC GGCAGGTTCG GCTATTCCAG GACGAGGAGA TCTACAGCGA CCTGTACCTG 
ACCGTATGCG AGTGGCCCAG CGACGCCTCC AAGGTCATCG TCTTCGGCTT CAACACCCGC 
TCGGCCAACG GGATGCTCAT GAACATGATG ATGATGAGTG ACGAGAACCA CCGTGACATC 
TACGTCAGCA CCGTGGCCGT GCCACCGCCA GGCCGCTGTG CTGCTTGCCA GGATGCCAGC 
CGAGCCCACC CAGGAGACCC GAATGCACAG TGCCTACGGC ATGGCTTCAT GCTGCACACC 
AAGTACCAGG TGGTCTACCC CTTCCCCACC TTCCAGCCCG CCTTCCAGCT CAAGAAGGAC 
CAGGTGGTGC TGCTCAACAC CAGCTACTCC CTGGTGGCCT GCGCCGTCTC CGTCCACTCG 
GCAGGTGACA GGAGTTTCTG CCAAATCCTG TATGACCACA GCACCTGCCC CCTGGCGCCT 
GCCAGCCCCC CTGAGCCCCA GAGCCCAGAG CTGCCCCCTG CCCTCCCCAG CTTCTGCCCT 
GAGGCGGCCC CAGCCCGTTC TTCTGGGTCT CCTGAGCCCT CGCCCGCCAT TGCCAAAGCC 
AAGGAGTTTG TGGCTGACAT CTTCCGCCGG GCCAAAGAGG CCAAGGGCGG GGTCCCTGAG 
GAAGCCCGGC CTGCCCTGTG CCCAGGACCC TCTGGCAGCC GCTGCCGTGC GCACTCTGAG 
CCCCTAGCCC TGTGTGGAGA GACGGCACCC CGGGACAGCC CCCCTGCCTC GGAGGCACCT 
GCCTCCGAGC CTGGCTATGT CAACTACACC AAGCTGTACT ATGTGCTGGA GTCCGGAGAG 
GGGACGGAGC CGGAGGATGA GTTGGAGGAC GACAAGATCT CCCTGCCCTT CGTGGTGACT 
GATCTTCGTG GCCGCAACCT GCGGCCCATG CGGGAGCGGA CTGCTGTCCA GGGCCAGTAC 
CTGACAGTGG AGCAGCTCAC ACTAGACTTC GAATATGTTA TCAATGAGGT CATCCGCCAC 
GACGCTACCT GGGGCCATCA GTTCTGTTCT TTCAGCGACT ATGACATCGT CATTCTGGAG 
GTCTGCCCAG AAACCAACCA GGTCCTCATC AACATTGGCC TGCTGCTCCT GGCCTTCCCG 
TCCCCCACTG AGGAGGGCCA GCTCCGACCA AAGACCTATC ACACCAGCCT CAAGGTGGCA 
TGGGACCTCA ACACAGGGAT CTTCGAGACA GTCAGTGTAG GCGACCTGAC TGAGGTCAAA 
GGGCAGACCA GCGGCAGTGT CTGGAGCTCC TACCGCAAGA GCTGCGTGGA CATGGTCATG 
AAGTGGCTGG TGCCGGAGAG CAGCGGCCGC TACGTCAACA GGATGACCAA TGAGGCGCTG 
CACAAAGGGT GCTCCCTGAA GGTTCTGGCG GACAGCGAGC GATATACGTG GATCGTGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq

NP_612362.2

Translation

MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCPEAAPARSSGSPEPSPAIAKAKEFVADIFRRAKEAKGGVPEEARPALCPGPSGSRCRAHSEPLALCGETAPRDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVTDLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL

Target ORF information:

RefSeq Version	NM_138353.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138353.2

ORF Insert Sequence:

ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC 
GGGGGAGCCG GAGGGAAGCG GGCAGCAGGG CGGCGGCGGG AGCACGTCCT CAAGCAGCTG 
GAGCGGGTCA AGATCAGCGG ACAGCTCTCC CCTCGCCTCT TCCGGAAGCT GCCTCCCCGG 
GTGTGCGTGT CCCTCAAGAA CATTGTGGAT GAGGACTTCC TCTATGCAGG ACATATCTTC 
CTGGGCTTTT CCAAATGCGG CCGCTACGTC CTCTCCTACA CCAGCAGCAG TGGGGATGAC 
GACTTCTCCT TCTACATCTA CCATCTGTAC TGGTGGGAGT TCAACGTTCA CAGCAAGCTC 
AAGCTGGTCC GGCAGGTTCG GCTATTCCAG GACGAGGAGA TCTACAGCGA CCTGTACCTG 
ACCGTATGCG AGTGGCCCAG CGACGCCTCC AAGGTCATCG TCTTCGGCTT CAACACCCGC 
TCGGCCAACG GGATGCTCAT GAACATGATG ATGATGAGTG ACGAGAACCA CCGTGACATC 
TACGTCAGCA CCGTGGCCGT GCCACCGCCA GGCCGCTGTG CTGCTTGCCA GGATGCCAGC 
CGAGCCCACC CAGGAGACCC GAATGCACAG TGCCTACGGC ATGGCTTCAT GCTGCACACC 
AAGTACCAGG TGGTCTACCC CTTCCCCACC TTCCAGCCCG CCTTCCAGCT CAAGAAGGAC 
CAGGTGGTGC TGCTCAACAC CAGCTACTCC CTGGTGGCCT GCGCCGTCTC CGTCCACTCG 
GCAGGTGACA GGAGTTTCTG CCAAATCCTG TATGACCACA GCACCTGCCC CCTGGCGCCT 
GCCAGCCCCC CTGAGCCCCA GAGCCCAGAG CTGCCCCCTG CCCTCCCCAG CTTCTGCCCT 
GAGGCGGCCC CAGCCCGTTC TTCTGGGTCT CCTGAGCCCT CGCCCGCCAT TGCCAAAGCC 
AAGGAGTTTG TGGCTGACAT CTTCCGCCGG GCCAAAGAGG CCAAGGGCGG GGTCCCTGAG 
GAAGCCCGGC CTGCCCTGTG CCCAGGACCC TCTGGCAGCC GCTGCCGTGC GCACTCTGAG 
CCCCTAGCCC TGTGTGGAGA GACGGCACCC CGGGACAGCC CCCCTGCCTC GGAGGCACCT 
GCCTCCGAGC CTGGCTATGT CAACTACACC AAGCTGTACT ATGTGCTGGA GTCCGGAGAG 
GGGACGGAGC CGGAGGATGA GTTGGAGGAC GACAAGATCT CCCTGCCCTT CGTGGTGACT 
GATCTTCGTG GCCGCAACCT GCGGCCCATG CGGGAGCGGA CTGCTGTCCA GGGCCAGTAC 
CTGACAGTGG AGCAGCTCAC ACTAGACTTC GAATATGTTA TCAATGAGGT CATCCGCCAC 
GACGCTACCT GGGGCCATCA GTTCTGTTCT TTCAGCGACT ATGACATCGT CATTCTGGAG 
GTCTGCCCAG AAACCAACCA GGTCCTCATC AACATTGGCC TGCTGCTCCT GGCCTTCCCG 
TCCCCCACTG AGGAGGGCCA GCTCCGACCA AAGACCTATC ACACCAGCCT CAAGGTGGCA 
TGGGACCTCA ACACAGGGAT CTTCGAGACA GTCAGTGTAG GCGACCTGAC TGAGGTCAAA 
GGGCAGACCA GCGGCAGTGT CTGGAGCTCC TACCGCAAGA GCTGCGTGGA CATGGTCATG 
AAGTGGCTGG TGCCGGAGAG CAGCGGCCGC TACGTCAACA GGATGACCAA TGAGGCGCTG 
CACAAAGGGT GCTCCCTGAA GGTTCTGGCG GACAGCGAGC GATATACGTG GATCGTGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

DCAF15 ( NM_138353.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_612362.2 Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.

Price & Availability↑

CloneID	OHu06074
Clone ID Related Accession (Same CDS sequence)	NM_138353.2 , NM_138353.3
Accession Version	NM_138353.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	DDB1- and CUL4-associated factor 15
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from HY003563.1, BC080575.1 and BC018894.2. On Jul 22, 2016 this sequence version replaced NM_138353.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.416831.1, BC080575.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC 
GGGGGAGCCG GAGGGAAGCG GGCAGCAGGG CGGCGGCGGG AGCACGTCCT CAAGCAGCTG 
GAGCGGGTCA AGATCAGCGG ACAGCTCTCC CCTCGCCTCT TCCGGAAGCT GCCTCCCCGG 
GTGTGCGTGT CCCTCAAGAA CATTGTGGAT GAGGACTTCC TCTATGCAGG ACATATCTTC 
CTGGGCTTTT CCAAATGCGG CCGCTACGTC CTCTCCTACA CCAGCAGCAG TGGGGATGAC 
GACTTCTCCT TCTACATCTA CCATCTGTAC TGGTGGGAGT TCAACGTTCA CAGCAAGCTC 
AAGCTGGTCC GGCAGGTTCG GCTATTCCAG GACGAGGAGA TCTACAGCGA CCTGTACCTG 
ACCGTATGCG AGTGGCCCAG CGACGCCTCC AAGGTCATCG TCTTCGGCTT CAACACCCGC 
TCGGCCAACG GGATGCTCAT GAACATGATG ATGATGAGTG ACGAGAACCA CCGTGACATC 
TACGTCAGCA CCGTGGCCGT GCCACCGCCA GGCCGCTGTG CTGCTTGCCA GGATGCCAGC 
CGAGCCCACC CAGGAGACCC GAATGCACAG TGCCTACGGC ATGGCTTCAT GCTGCACACC 
AAGTACCAGG TGGTCTACCC CTTCCCCACC TTCCAGCCCG CCTTCCAGCT CAAGAAGGAC 
CAGGTGGTGC TGCTCAACAC CAGCTACTCC CTGGTGGCCT GCGCCGTCTC CGTCCACTCG 
GCAGGTGACA GGAGTTTCTG CCAAATCCTG TATGACCACA GCACCTGCCC CCTGGCGCCT 
GCCAGCCCCC CTGAGCCCCA GAGCCCAGAG CTGCCCCCTG CCCTCCCCAG CTTCTGCCCT 
GAGGCGGCCC CAGCCCGTTC TTCTGGGTCT CCTGAGCCCT CGCCCGCCAT TGCCAAAGCC 
AAGGAGTTTG TGGCTGACAT CTTCCGCCGG GCCAAAGAGG CCAAGGGCGG GGTCCCTGAG 
GAAGCCCGGC CTGCCCTGTG CCCAGGACCC TCTGGCAGCC GCTGCCGTGC GCACTCTGAG 
CCCCTAGCCC TGTGTGGAGA GACGGCACCC CGGGACAGCC CCCCTGCCTC GGAGGCACCT 
GCCTCCGAGC CTGGCTATGT CAACTACACC AAGCTGTACT ATGTGCTGGA GTCCGGAGAG 
GGGACGGAGC CGGAGGATGA GTTGGAGGAC GACAAGATCT CCCTGCCCTT CGTGGTGACT 
GATCTTCGTG GCCGCAACCT GCGGCCCATG CGGGAGCGGA CTGCTGTCCA GGGCCAGTAC 
CTGACAGTGG AGCAGCTCAC ACTAGACTTC GAATATGTTA TCAATGAGGT CATCCGCCAC 
GACGCTACCT GGGGCCATCA GTTCTGTTCT TTCAGCGACT ATGACATCGT CATTCTGGAG 
GTCTGCCCAG AAACCAACCA GGTCCTCATC AACATTGGCC TGCTGCTCCT GGCCTTCCCG 
TCCCCCACTG AGGAGGGCCA GCTCCGACCA AAGACCTATC ACACCAGCCT CAAGGTGGCA 
TGGGACCTCA ACACAGGGAT CTTCGAGACA GTCAGTGTAG GCGACCTGAC TGAGGTCAAA 
GGGCAGACCA GCGGCAGTGT CTGGAGCTCC TACCGCAAGA GCTGCGTGGA CATGGTCATG 
AAGTGGCTGG TGCCGGAGAG CAGCGGCCGC TACGTCAACA GGATGACCAA TGAGGCGCTG 
CACAAAGGGT GCTCCCTGAA GGTTCTGGCG GACAGCGAGC GATATACGTG GATCGTGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_612362.2
CDS	40..1842
Translation	MAPSSKSERNSGAGSGGGGPGGAGGKRAAGRRREHVLKQLERVKISGQLSPRLFRKLPPRVCVSLKNIVDEDFLYAGHIFLGFSKCGRYVLSYTSSSGDDDFSFYIYHLYWWEFNVHSKLKLVRQVRLFQDEEIYSDLYLTVCEWPSDASKVIVFGFNTRSANGMLMNMMMMSDENHRDIYVSTVAVPPPGRCAACQDASRAHPGDPNAQCLRHGFMLHTKYQVVYPFPTFQPAFQLKKDQVVLLNTSYSLVACAVSVHSAGDRSFCQILYDHSTCPLAPASPPEPQSPELPPALPSFCPEAAPARSSGSPEPSPAIAKAKEFVADIFRRAKEAKGGVPEEARPALCPGPSGSRCRAHSEPLALCGETAPRDSPPASEAPASEPGYVNYTKLYYVLESGEGTEPEDELEDDKISLPFVVTDLRGRNLRPMRERTAVQGQYLTVEQLTLDFEYVINEVIRHDATWGHQFCSFSDYDIVILEVCPETNQVLINIGLLLLAFPSPTEEGQLRPKTYHTSLKVAWDLNTGIFETVSVGDLTEVKGQTSGSVWSSYRKSCVDMVMKWLVPESSGRYVNRMTNEALHKGCSLKVLADSERYTWIVL

Target ORF information:

RefSeq Version	NM_138353.3
Organism	Homo sapiens(human)
Definition	Homo sapiens DDB1 and CUL4 associated factor 15 (DCAF15), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_138353.3

ORF Insert Sequence:

ATGGCGCCCA GCTCGAAATC GGAGCGGAAC AGCGGGGCTG GGAGCGGCGG CGGCGGCCCC 
GGGGGAGCCG GAGGGAAGCG GGCAGCAGGG CGGCGGCGGG AGCACGTCCT CAAGCAGCTG 
GAGCGGGTCA AGATCAGCGG ACAGCTCTCC CCTCGCCTCT TCCGGAAGCT GCCTCCCCGG 
GTGTGCGTGT CCCTCAAGAA CATTGTGGAT GAGGACTTCC TCTATGCAGG ACATATCTTC 
CTGGGCTTTT CCAAATGCGG CCGCTACGTC CTCTCCTACA CCAGCAGCAG TGGGGATGAC 
GACTTCTCCT TCTACATCTA CCATCTGTAC TGGTGGGAGT TCAACGTTCA CAGCAAGCTC 
AAGCTGGTCC GGCAGGTTCG GCTATTCCAG GACGAGGAGA TCTACAGCGA CCTGTACCTG 
ACCGTATGCG AGTGGCCCAG CGACGCCTCC AAGGTCATCG TCTTCGGCTT CAACACCCGC 
TCGGCCAACG GGATGCTCAT GAACATGATG ATGATGAGTG ACGAGAACCA CCGTGACATC 
TACGTCAGCA CCGTGGCCGT GCCACCGCCA GGCCGCTGTG CTGCTTGCCA GGATGCCAGC 
CGAGCCCACC CAGGAGACCC GAATGCACAG TGCCTACGGC ATGGCTTCAT GCTGCACACC 
AAGTACCAGG TGGTCTACCC CTTCCCCACC TTCCAGCCCG CCTTCCAGCT CAAGAAGGAC 
CAGGTGGTGC TGCTCAACAC CAGCTACTCC CTGGTGGCCT GCGCCGTCTC CGTCCACTCG 
GCAGGTGACA GGAGTTTCTG CCAAATCCTG TATGACCACA GCACCTGCCC CCTGGCGCCT 
GCCAGCCCCC CTGAGCCCCA GAGCCCAGAG CTGCCCCCTG CCCTCCCCAG CTTCTGCCCT 
GAGGCGGCCC CAGCCCGTTC TTCTGGGTCT CCTGAGCCCT CGCCCGCCAT TGCCAAAGCC 
AAGGAGTTTG TGGCTGACAT CTTCCGCCGG GCCAAAGAGG CCAAGGGCGG GGTCCCTGAG 
GAAGCCCGGC CTGCCCTGTG CCCAGGACCC TCTGGCAGCC GCTGCCGTGC GCACTCTGAG 
CCCCTAGCCC TGTGTGGAGA GACGGCACCC CGGGACAGCC CCCCTGCCTC GGAGGCACCT 
GCCTCCGAGC CTGGCTATGT CAACTACACC AAGCTGTACT ATGTGCTGGA GTCCGGAGAG 
GGGACGGAGC CGGAGGATGA GTTGGAGGAC GACAAGATCT CCCTGCCCTT CGTGGTGACT 
GATCTTCGTG GCCGCAACCT GCGGCCCATG CGGGAGCGGA CTGCTGTCCA GGGCCAGTAC 
CTGACAGTGG AGCAGCTCAC ACTAGACTTC GAATATGTTA TCAATGAGGT CATCCGCCAC 
GACGCTACCT GGGGCCATCA GTTCTGTTCT TTCAGCGACT ATGACATCGT CATTCTGGAG 
GTCTGCCCAG AAACCAACCA GGTCCTCATC AACATTGGCC TGCTGCTCCT GGCCTTCCCG 
TCCCCCACTG AGGAGGGCCA GCTCCGACCA AAGACCTATC ACACCAGCCT CAAGGTGGCA 
TGGGACCTCA ACACAGGGAT CTTCGAGACA GTCAGTGTAG GCGACCTGAC TGAGGTCAAA 
GGGCAGACCA GCGGCAGTGT CTGGAGCTCC TACCGCAAGA GCTGCGTGGA CATGGTCATG 
AAGTGGCTGG TGCCGGAGAG CAGCGGCCGC TACGTCAACA GGATGACCAA TGAGGCGCTG 
CACAAAGGGT GCTCCCTGAA GGTTCTGGCG GACAGCGAGC GATATACGTG GATCGTGCTG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Selective degradation of splicing factor CAPER? by anticancer sulfonamides.
Nature chemical biology13(6)675-680(2017 Jun)
Uehara T,Minoshima Y,Sagane K,Sugi NH,Mitsuhashi KO,Yamamoto N,Kamiyama H,Takahashi K,Kotake Y,Uesugi M,Yokoi A,Inoue A,Yoshida T,Mabuchi M,Tanaka A,Owa T

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.
Science (New York, N.Y.)356(6336)(2017 04)
Han T,Goralski M,Gaskill N,Capota E,Kim J,Ting TC,Xie Y,Williams NS,Nijhawan D

A family of diverse Cul4-Ddb1-interacting proteins includes Cdt2, which is required for S phase destruction of the replication factor Cdt1.
Molecular cell23(5)709-21(2006 Sep)
Jin J,Arias EE,Chen J,Harper JW,Walter JC

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DCAF15 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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