MBTPS1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	MBTPS1
Entrez Gene ID	8720
Full Name	membrane bound transcription factor peptidase, site 1
Synonyms	PCSK8,S1P,SKI-1
General protein information	Preferred Names membrane bound transcription factor peptidase, site 1 Names membrane-bound transcription factor site-1 protease endopeptidase S1P proprotein convertase subtilisin/kexin type 8 site-1 protease subtilisin/kexin isozyme-1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16q23.3-q24.1
Summary	This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired. It encodes a type 1 membrane bound protease which is ubiquitously expressed and regulates cholesterol or lipid homeostasis via cleavage of substrates at non-basic residues. Mutations in this gene may be associated with lysosomal dysfunction. [provided by RefSeq, Feb 2014].
Disorder MIM:	603355

mRNA and Protein(s)

mRNA	Protein	Name
XM_017023817.2	XP_016879306.1	membrane-bound transcription factor site-1 protease isoform X2
XM_017023816.1	XP_016879305.1	membrane-bound transcription factor site-1 protease isoform X1
NM_003791.4	NP_003782.1	membrane-bound transcription factor site-1 protease preproprotein
NM_003791.3	NP_003782.1	membrane-bound transcription factor site-1 protease preproprotein
XM_017023817.1	XP_016879306.1	membrane-bound transcription factor site-1 protease isoform X2
XM_017023816.2	XP_016879305.1	membrane-bound transcription factor site-1 protease isoform X1
XM_024450477.1	XP_024306245.1	membrane-bound transcription factor site-1 protease isoform X2

Pathways from BioSystems

Homologies

	MBTPS1	XP_001112150.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012203	XP_320328.4
Oryza sativa (rice)	Os06g0163500	NP_001056897.1
Bos taurus (cattle)	MBTPS1	NP_001020501.2
Homo sapiens (human)	MBTPS1	NP_003782.1
Canis lupus familiaris (dog)	MBTPS1	XP_850300.1
Gallus gallus (chicken)	MBTPS1	XP_003641945.1
Danio rerio (zebrafish)	mbtps1	NP_954683.1
Drosophila melanogaster (fruit fly)	S1P	NP_649337.2
Pan troglodytes (chimpanzee)	MBTPS1	XP_003315258.1
Arabidopsis thaliana (thale cress)	S1P	NP_197467.1
Xenopus tropicalis (tropical clawed frog)	mbtps1	NP_001072791.2
Mus musculus (house mouse)	Mbtps1	NP_062683.3
Rattus norvegicus (Norway rat)	Mbtps1	NP_446021.1

Gene Ontology
Bibliography

Related articles in PubMed

Genetics of the human face: Identification of large-effect single gene variants.
Crouch DJM, Winney B, Koppen WP, Christmas WJ, Hutnik K, Day T, Meena D, Boumertit A, Hysi P, Nessa A, Spector TD, Kittler J, Bodmer WF
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)

Site-1 protease and lysosomal homeostasis.
Velho RV, De Pace R, Kl?nder S, Di Lorenzo G, Schweizer M, Braulke T, Pohl S
Biochimica et biophysica acta1864(11 Pt B)2162-2168(2017 11)

Site-1 protease is required for the generation of soluble (pro)renin receptor.
Nakagawa T, Suzuki-Nakagawa C, Watanabe A, Asami E, Matsumoto M, Nakano M, Ebihara A, Uddin MN, Suzuki F
Journal of biochemistry161(4)369-379(2017 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results suggest that (pro)renin receptor (s(P)RR) is generated by sequential processing by site-1 protease (S1P) and furin protein.
Title: Site-1 protease is required for the generation of soluble (pro)renin receptor.

primordial SKI-1/S1P likely contained a simpler prodomain consisting of the highly conserved AB fragment that represents an independent folding unit
Title: Mechanism of Folding and Activation of Subtilisin Kexin Isozyme-1 (SKI-1)/Site-1 Protease (S1P).

S1P substrate-dependent regulatory mechanisms for lipid synthesis and biogenesis of lysosomes are different
Title: Site-1 protease-activated formation of lysosomal targeting motifs is independent of the lipogenic transcription control.

Incompletely matured forms of SKI-1/S1P further process cellular and viral substrates in distinct subcellular compartments.
Title: Zymogen activation and subcellular activity of subtilisin kexin isozyme 1/site 1 protease.

The interaction between S1P and C5a plays an important role in neutrophils for antineutrophil cytoplasmic antibody -mediated activation
Title: The interaction between C5a and sphingosine-1-phosphate in neutrophils for antineutrophil cytoplasmic antibody mediated activation.

The following MBTPS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MBTPS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20949	NM_003791.4 Latest version!	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu86335	XM_017023816.2 Latest version!	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu86336	XM_024450477.1 Latest version!	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu86336	XM_017023817.2 Latest version!	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu20949	NM_003791.3	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$274.50-$384.30 $549.00
OHu86336	XM_017023817.1	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu86335	XM_017023816.1	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

MBTPS1 ( NM_003791.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003782.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.

Price & Availability↑

CloneID	OHu20949
Clone ID Related Accession (Same CDS sequence)	NM_003791.4 , NM_003791.3
Accession Version	NM_003791.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP364386.1, D42053.1, BC114555.1 and BM680126.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_003791.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.232414.1, SRR1803612.128417.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000343411.8/ ENSP00000344223.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCTTG TCAACATCTG GCTGCTTCTG CTCGTGGTTT TGCTCTGTGG GAAGAAACAT 
CTGGGCGACA GACTGGAAAA GAAATCTTTT GAAAAGGCCC CATGCCCTGG CTGTTCCCAC 
CTGACTTTGA AGGTGGAATT CTCATCAACA GTTGTGGAAT ATGAATATAT TGTGGCTTTC 
AATGGATACT TTACAGCCAA AGCTAGAAAT TCATTTATTT CAAGTGCCCT GAAGAGCAGT 
GAAGTAGACA ATTGGAGAAT TATACCTCGA AACAATCCAT CCAGTGACTA CCCTAGTGAT 
TTTGAGGTGA TTCAGATAAA AGAAAAACAG AAAGCGGGGC TGCTAACACT TGAAGATCAT 
CCAAACATCA AACGGGTCAC GCCCCAACGA AAAGTCTTTC GTTCCCTCAA GTATGCTGAA 
TCTGACCCCA CAGTACCCTG CAATGAAACC CGGTGGAGCC AGAAGTGGCA ATCATCACGT 
CCCCTGCGAA GAGCCAGCCT CTCCCTGGGC TCTGGCTTCT GGCATGCTAC GGGAAGGCAT 
TCGAGCAGAC GGCTGCTGAG AGCCATCCCG CGCCAGGTTG CCCAGACACT GCAGGCAGAT 
GTGCTCTGGC AGATGGGATA TACAGGTGCT AATGTAAGAG TTGCTGTTTT TGACACTGGG 
CTGAGCGAGA AGCATCCCCA CTTCAAAAAT GTGAAGGAGA GAACCAACTG GACCAACGAG 
CGAACGCTGG ACGATGGGTT GGGCCATGGC ACATTCGTGG CAGGTGTGAT AGCCAGCATG 
AGGGAGTGCC AAGGATTTGC TCCAGATGCA GAACTTCACA TTTTCAGGGT CTTTACCAAT 
AATCAGGTAT CTTACACATC TTGGTTTTTG GACGCCTTCA ACTATGCCAT TTTAAAGAAG 
ATCGACGTGT TAAACCTCAG CATCGGCGGC CCGGACTTCA TGGATCATCC GTTTGTTGAC 
AAGGTGTGGG AATTAACAGC TAACAATGTA ATCATGGTTT CTGCTATTGG CAATGACGGA 
CCTCTTTATG GCACTCTGAA TAACCCTGCT GATCAAATGG ATGTGATTGG AGTAGGCGGC 
ATTGACTTTG AAGATAACAT CGCCCGCTTT TCTTCAAGGG GAATGACTAC CTGGGAGCTA 
CCAGGAGGCT ACGGTCGCAT GAAACCTGAC ATTGTCACCT ATGGTGCTGG CGTGCGGGGT 
TCTGGCGTGA AAGGGGGGTG CCGGGCCCTC TCAGGGACCA GTGTTGCTTC TCCAGTGGTT 
GCAGGTGCTG TCACCTTGTT AGTGAGCACA GTCCAGAAGC GTGAGCTGGT GAATCCCGCC 
AGTATGAAGC AGGCCCTGAT CGCGTCAGCC CGGAGGCTCC CCGGGGTCAA CATGTTTGAG 
CAAGGCCACG GCAAGCTCGA TCTGCTCAGA GCCTATCAGA TCCTCAACAG CTACAAGCCA 
CAGGCAAGTT TGAGCCCCAG CTACATAGAT CTGACTGAGT GTCCCTACAT GTGGCCCTAC 
TGCTCCCAGC CCATCTACTA TGGAGGAATG CCGACAGTTG TTAATGTCAC CATCCTCAAC 
GGCATGGGAG TCACAGGAAG AATTGTAGAT AAGCCTGACT GGCAGCCCTA TTTGCCACAG 
AACGGAGACA ACATTGAAGT TGCCTTCTCC TACTCCTCGG TCTTATGGCC TTGGTCGGGC 
TACCTGGCCA TCTCCATTTC TGTGACCAAG AAAGCGGCTT CCTGGGAAGG CATTGCTCAG 
GGCCATGTCA TGATCACTGT GGCTTCCCCA GCAGAGACAG AGTCAAAAAA TGGTGCAGAA 
CAGACTTCAA CAGTAAAGCT CCCCATTAAG GTGAAGATAA TTCCTACTCC CCCGCGAAGC 
AAGAGAGTTC TCTGGGATCA GTACCACAAC CTCCGCTATC CACCTGGCTA TTTCCCCAGG 
GATAATTTAA GGATGAAGAA TGACCCTTTA GACTGGAATG GTGATCACAT CCACACCAAT 
TTCAGGGATA TGTACCAGCA TCTGAGAAGC ATGGGCTACT TTGTAGAGGT CCTCGGGGCC 
CCCTTCACGT GTTTTGATGC CAGTCAGTAT GGCACTTTGC TGATGGTGGA CAGTGAGGAG 
GAGTACTTCC CTGAAGAGAT CGCCAAGCTC CGGAGGGACG TGGACAACGG CCTCTCGCTC 
GTCATCTTCA GTGACTGGTA CAACACTTCT GTTATGAGAA AAGTGAAGTT TTATGATGAA 
AACACAAGGC AGTGGTGGAT GCCGGATACC GGAGGAGCTA ACATCCCAGC TCTGAATGAG 
CTGCTGTCTG TGTGGAACAT GGGGTTCAGC GATGGCCTGT ATGAAGGGGA GTTCACCCTG 
GCCAACCATG ACATGTATTA TGCGTCAGGG TGCAGCATCG CGAAGTTTCC AGAAGATGGC 
GTCGTGATAA CACAGACTTT CAAGGACCAA GGATTGGAGG TTTTAAAGCA GGAAACAGCA 
GTTGTTGAAA ACGTCCCCAT TTTGGGACTT TATCAGATTC CAGCTGAGGG TGGAGGCCGG 
ATTGTACTGT ATGGGGACTC CAATTGCTTG GATGACAGTC ACCGACAGAA GGACTGCTTT 
TGGCTTCTGG ATGCCCTCCT CCAGTACACA TCGTATGGGG TGACACCGCC TAGCCTCAGT 
CACTCTGGGA ACCGCCAGCG CCCTCCCAGT GGAGCAGGCT CAGTCACTCC AGAGAGGATG 
GAAGGAAACC ATCTTCATCG GTACTCCAAG GTTCTGGAGG CCCATTTGGG AGACCCAAAA 
CCTCGGCCTC TACCAGCCTG TCCACGCTTG TCTTGGGCCA AGCCACAGCC TTTAAACGAG 
ACGGCGCCCA GTAACCTTTG GAAACATCAG AAGCTACTCT CCATTGACCT GGACAAGGTG 
GTGTTACCCA ACTTTCGATC GAATCGCCCT CAAGTGAGGC CCTTGTCCCC TGGAGAGAGC 
GGCGCCTGGG ACATTCCTGG AGGGATCATG CCTGGCCGCT ACAACCAGGA GGTGGGCCAG 
ACCATTCCTG TCTTTGCCTT CCTGGGAGCC ATGGTGGTCC TGGCCTTCTT TGTGGTACAA 
ATCAACAAGG CCAAGAGCAG GCCGAAGCGG AGGAAGCCCA GGGTGAAGCG CCCGCAGCTC 
ATGCAGCAGG TTCACCCGCC AAAGACCCCT TCGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003782.1
CDS	533..3691
Translation	MKLVNIWLLLLVVLLCGKKHLGDRLEKKSFEKAPCPGCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASMKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	NM_003791.4
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003791.4

ORF Insert Sequence:

ATGAAGCTTG TCAACATCTG GCTGCTTCTG CTCGTGGTTT TGCTCTGTGG GAAGAAACAT 
CTGGGCGACA GACTGGAAAA GAAATCTTTT GAAAAGGCCC CATGCCCTGG CTGTTCCCAC 
CTGACTTTGA AGGTGGAATT CTCATCAACA GTTGTGGAAT ATGAATATAT TGTGGCTTTC 
AATGGATACT TTACAGCCAA AGCTAGAAAT TCATTTATTT CAAGTGCCCT GAAGAGCAGT 
GAAGTAGACA ATTGGAGAAT TATACCTCGA AACAATCCAT CCAGTGACTA CCCTAGTGAT 
TTTGAGGTGA TTCAGATAAA AGAAAAACAG AAAGCGGGGC TGCTAACACT TGAAGATCAT 
CCAAACATCA AACGGGTCAC GCCCCAACGA AAAGTCTTTC GTTCCCTCAA GTATGCTGAA 
TCTGACCCCA CAGTACCCTG CAATGAAACC CGGTGGAGCC AGAAGTGGCA ATCATCACGT 
CCCCTGCGAA GAGCCAGCCT CTCCCTGGGC TCTGGCTTCT GGCATGCTAC GGGAAGGCAT 
TCGAGCAGAC GGCTGCTGAG AGCCATCCCG CGCCAGGTTG CCCAGACACT GCAGGCAGAT 
GTGCTCTGGC AGATGGGATA TACAGGTGCT AATGTAAGAG TTGCTGTTTT TGACACTGGG 
CTGAGCGAGA AGCATCCCCA CTTCAAAAAT GTGAAGGAGA GAACCAACTG GACCAACGAG 
CGAACGCTGG ACGATGGGTT GGGCCATGGC ACATTCGTGG CAGGTGTGAT AGCCAGCATG 
AGGGAGTGCC AAGGATTTGC TCCAGATGCA GAACTTCACA TTTTCAGGGT CTTTACCAAT 
AATCAGGTAT CTTACACATC TTGGTTTTTG GACGCCTTCA ACTATGCCAT TTTAAAGAAG 
ATCGACGTGT TAAACCTCAG CATCGGCGGC CCGGACTTCA TGGATCATCC GTTTGTTGAC 
AAGGTGTGGG AATTAACAGC TAACAATGTA ATCATGGTTT CTGCTATTGG CAATGACGGA 
CCTCTTTATG GCACTCTGAA TAACCCTGCT GATCAAATGG ATGTGATTGG AGTAGGCGGC 
ATTGACTTTG AAGATAACAT CGCCCGCTTT TCTTCAAGGG GAATGACTAC CTGGGAGCTA 
CCAGGAGGCT ACGGTCGCAT GAAACCTGAC ATTGTCACCT ATGGTGCTGG CGTGCGGGGT 
TCTGGCGTGA AAGGGGGGTG CCGGGCCCTC TCAGGGACCA GTGTTGCTTC TCCAGTGGTT 
GCAGGTGCTG TCACCTTGTT AGTGAGCACA GTCCAGAAGC GTGAGCTGGT GAATCCCGCC 
AGTATGAAGC AGGCCCTGAT CGCGTCAGCC CGGAGGCTCC CCGGGGTCAA CATGTTTGAG 
CAAGGCCACG GCAAGCTCGA TCTGCTCAGA GCCTATCAGA TCCTCAACAG CTACAAGCCA 
CAGGCAAGTT TGAGCCCCAG CTACATAGAT CTGACTGAGT GTCCCTACAT GTGGCCCTAC 
TGCTCCCAGC CCATCTACTA TGGAGGAATG CCGACAGTTG TTAATGTCAC CATCCTCAAC 
GGCATGGGAG TCACAGGAAG AATTGTAGAT AAGCCTGACT GGCAGCCCTA TTTGCCACAG 
AACGGAGACA ACATTGAAGT TGCCTTCTCC TACTCCTCGG TCTTATGGCC TTGGTCGGGC 
TACCTGGCCA TCTCCATTTC TGTGACCAAG AAAGCGGCTT CCTGGGAAGG CATTGCTCAG 
GGCCATGTCA TGATCACTGT GGCTTCCCCA GCAGAGACAG AGTCAAAAAA TGGTGCAGAA 
CAGACTTCAA CAGTAAAGCT CCCCATTAAG GTGAAGATAA TTCCTACTCC CCCGCGAAGC 
AAGAGAGTTC TCTGGGATCA GTACCACAAC CTCCGCTATC CACCTGGCTA TTTCCCCAGG 
GATAATTTAA GGATGAAGAA TGACCCTTTA GACTGGAATG GTGATCACAT CCACACCAAT 
TTCAGGGATA TGTACCAGCA TCTGAGAAGC ATGGGCTACT TTGTAGAGGT CCTCGGGGCC 
CCCTTCACGT GTTTTGATGC CAGTCAGTAT GGCACTTTGC TGATGGTGGA CAGTGAGGAG 
GAGTACTTCC CTGAAGAGAT CGCCAAGCTC CGGAGGGACG TGGACAACGG CCTCTCGCTC 
GTCATCTTCA GTGACTGGTA CAACACTTCT GTTATGAGAA AAGTGAAGTT TTATGATGAA 
AACACAAGGC AGTGGTGGAT GCCGGATACC GGAGGAGCTA ACATCCCAGC TCTGAATGAG 
CTGCTGTCTG TGTGGAACAT GGGGTTCAGC GATGGCCTGT ATGAAGGGGA GTTCACCCTG 
GCCAACCATG ACATGTATTA TGCGTCAGGG TGCAGCATCG CGAAGTTTCC AGAAGATGGC 
GTCGTGATAA CACAGACTTT CAAGGACCAA GGATTGGAGG TTTTAAAGCA GGAAACAGCA 
GTTGTTGAAA ACGTCCCCAT TTTGGGACTT TATCAGATTC CAGCTGAGGG TGGAGGCCGG 
ATTGTACTGT ATGGGGACTC CAATTGCTTG GATGACAGTC ACCGACAGAA GGACTGCTTT 
TGGCTTCTGG ATGCCCTCCT CCAGTACACA TCGTATGGGG TGACACCGCC TAGCCTCAGT 
CACTCTGGGA ACCGCCAGCG CCCTCCCAGT GGAGCAGGCT CAGTCACTCC AGAGAGGATG 
GAAGGAAACC ATCTTCATCG GTACTCCAAG GTTCTGGAGG CCCATTTGGG AGACCCAAAA 
CCTCGGCCTC TACCAGCCTG TCCACGCTTG TCTTGGGCCA AGCCACAGCC TTTAAACGAG 
ACGGCGCCCA GTAACCTTTG GAAACATCAG AAGCTACTCT CCATTGACCT GGACAAGGTG 
GTGTTACCCA ACTTTCGATC GAATCGCCCT CAAGTGAGGC CCTTGTCCCC TGGAGAGAGC 
GGCGCCTGGG ACATTCCTGG AGGGATCATG CCTGGCCGCT ACAACCAGGA GGTGGGCCAG 
ACCATTCCTG TCTTTGCCTT CCTGGGAGCC ATGGTGGTCC TGGCCTTCTT TGTGGTACAA 
ATCAACAAGG CCAAGAGCAG GCCGAAGCGG AGGAAGCCCA GGGTGAAGCG CCCGCAGCTC 
ATGCAGCAGG TTCACCCGCC AAAGACCCCT TCGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( NM_003791.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003782.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.

Price & Availability↑

CloneID	OHu20949
Clone ID Related Accession (Same CDS sequence)	NM_003791.4 , NM_003791.3
Accession Version	NM_003791.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3159bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP364386.1, D42053.1, BC114555.1 and BM680126.1. This sequence is a reference standard in the RefSeqGene project. On Feb 4, 2014 this sequence version replaced NM_003791.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.232414.1, SRR1803612.128417.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCTTG TCAACATCTG GCTGCTTCTG CTCGTGGTTT TGCTCTGTGG GAAGAAACAT 
CTGGGCGACA GACTGGAAAA GAAATCTTTT GAAAAGGCCC CATGCCCTGG CTGTTCCCAC 
CTGACTTTGA AGGTGGAATT CTCATCAACA GTTGTGGAAT ATGAATATAT TGTGGCTTTC 
AATGGATACT TTACAGCCAA AGCTAGAAAT TCATTTATTT CAAGTGCCCT GAAGAGCAGT 
GAAGTAGACA ATTGGAGAAT TATACCTCGA AACAATCCAT CCAGTGACTA CCCTAGTGAT 
TTTGAGGTGA TTCAGATAAA AGAAAAACAG AAAGCGGGGC TGCTAACACT TGAAGATCAT 
CCAAACATCA AACGGGTCAC GCCCCAACGA AAAGTCTTTC GTTCCCTCAA GTATGCTGAA 
TCTGACCCCA CAGTACCCTG CAATGAAACC CGGTGGAGCC AGAAGTGGCA ATCATCACGT 
CCCCTGCGAA GAGCCAGCCT CTCCCTGGGC TCTGGCTTCT GGCATGCTAC GGGAAGGCAT 
TCGAGCAGAC GGCTGCTGAG AGCCATCCCG CGCCAGGTTG CCCAGACACT GCAGGCAGAT 
GTGCTCTGGC AGATGGGATA TACAGGTGCT AATGTAAGAG TTGCTGTTTT TGACACTGGG 
CTGAGCGAGA AGCATCCCCA CTTCAAAAAT GTGAAGGAGA GAACCAACTG GACCAACGAG 
CGAACGCTGG ACGATGGGTT GGGCCATGGC ACATTCGTGG CAGGTGTGAT AGCCAGCATG 
AGGGAGTGCC AAGGATTTGC TCCAGATGCA GAACTTCACA TTTTCAGGGT CTTTACCAAT 
AATCAGGTAT CTTACACATC TTGGTTTTTG GACGCCTTCA ACTATGCCAT TTTAAAGAAG 
ATCGACGTGT TAAACCTCAG CATCGGCGGC CCGGACTTCA TGGATCATCC GTTTGTTGAC 
AAGGTGTGGG AATTAACAGC TAACAATGTA ATCATGGTTT CTGCTATTGG CAATGACGGA 
CCTCTTTATG GCACTCTGAA TAACCCTGCT GATCAAATGG ATGTGATTGG AGTAGGCGGC 
ATTGACTTTG AAGATAACAT CGCCCGCTTT TCTTCAAGGG GAATGACTAC CTGGGAGCTA 
CCAGGAGGCT ACGGTCGCAT GAAACCTGAC ATTGTCACCT ATGGTGCTGG CGTGCGGGGT 
TCTGGCGTGA AAGGGGGGTG CCGGGCCCTC TCAGGGACCA GTGTTGCTTC TCCAGTGGTT 
GCAGGTGCTG TCACCTTGTT AGTGAGCACA GTCCAGAAGC GTGAGCTGGT GAATCCCGCC 
AGTATGAAGC AGGCCCTGAT CGCGTCAGCC CGGAGGCTCC CCGGGGTCAA CATGTTTGAG 
CAAGGCCACG GCAAGCTCGA TCTGCTCAGA GCCTATCAGA TCCTCAACAG CTACAAGCCA 
CAGGCAAGTT TGAGCCCCAG CTACATAGAT CTGACTGAGT GTCCCTACAT GTGGCCCTAC 
TGCTCCCAGC CCATCTACTA TGGAGGAATG CCGACAGTTG TTAATGTCAC CATCCTCAAC 
GGCATGGGAG TCACAGGAAG AATTGTAGAT AAGCCTGACT GGCAGCCCTA TTTGCCACAG 
AACGGAGACA ACATTGAAGT TGCCTTCTCC TACTCCTCGG TCTTATGGCC TTGGTCGGGC 
TACCTGGCCA TCTCCATTTC TGTGACCAAG AAAGCGGCTT CCTGGGAAGG CATTGCTCAG 
GGCCATGTCA TGATCACTGT GGCTTCCCCA GCAGAGACAG AGTCAAAAAA TGGTGCAGAA 
CAGACTTCAA CAGTAAAGCT CCCCATTAAG GTGAAGATAA TTCCTACTCC CCCGCGAAGC 
AAGAGAGTTC TCTGGGATCA GTACCACAAC CTCCGCTATC CACCTGGCTA TTTCCCCAGG 
GATAATTTAA GGATGAAGAA TGACCCTTTA GACTGGAATG GTGATCACAT CCACACCAAT 
TTCAGGGATA TGTACCAGCA TCTGAGAAGC ATGGGCTACT TTGTAGAGGT CCTCGGGGCC 
CCCTTCACGT GTTTTGATGC CAGTCAGTAT GGCACTTTGC TGATGGTGGA CAGTGAGGAG 
GAGTACTTCC CTGAAGAGAT CGCCAAGCTC CGGAGGGACG TGGACAACGG CCTCTCGCTC 
GTCATCTTCA GTGACTGGTA CAACACTTCT GTTATGAGAA AAGTGAAGTT TTATGATGAA 
AACACAAGGC AGTGGTGGAT GCCGGATACC GGAGGAGCTA ACATCCCAGC TCTGAATGAG 
CTGCTGTCTG TGTGGAACAT GGGGTTCAGC GATGGCCTGT ATGAAGGGGA GTTCACCCTG 
GCCAACCATG ACATGTATTA TGCGTCAGGG TGCAGCATCG CGAAGTTTCC AGAAGATGGC 
GTCGTGATAA CACAGACTTT CAAGGACCAA GGATTGGAGG TTTTAAAGCA GGAAACAGCA 
GTTGTTGAAA ACGTCCCCAT TTTGGGACTT TATCAGATTC CAGCTGAGGG TGGAGGCCGG 
ATTGTACTGT ATGGGGACTC CAATTGCTTG GATGACAGTC ACCGACAGAA GGACTGCTTT 
TGGCTTCTGG ATGCCCTCCT CCAGTACACA TCGTATGGGG TGACACCGCC TAGCCTCAGT 
CACTCTGGGA ACCGCCAGCG CCCTCCCAGT GGAGCAGGCT CAGTCACTCC AGAGAGGATG 
GAAGGAAACC ATCTTCATCG GTACTCCAAG GTTCTGGAGG CCCATTTGGG AGACCCAAAA 
CCTCGGCCTC TACCAGCCTG TCCACGCTTG TCTTGGGCCA AGCCACAGCC TTTAAACGAG 
ACGGCGCCCA GTAACCTTTG GAAACATCAG AAGCTACTCT CCATTGACCT GGACAAGGTG 
GTGTTACCCA ACTTTCGATC GAATCGCCCT CAAGTGAGGC CCTTGTCCCC TGGAGAGAGC 
GGCGCCTGGG ACATTCCTGG AGGGATCATG CCTGGCCGCT ACAACCAGGA GGTGGGCCAG 
ACCATTCCTG TCTTTGCCTT CCTGGGAGCC ATGGTGGTCC TGGCCTTCTT TGTGGTACAA 
ATCAACAAGG CCAAGAGCAG GCCGAAGCGG AGGAAGCCCA GGGTGAAGCG CCCGCAGCTC 
ATGCAGCAGG TTCACCCGCC AAAGACCCCT TCGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003782.1
CDS	534..3692
Translation	MKLVNIWLLLLVVLLCGKKHLGDRLEKKSFEKAPCPGCSHLTLKVEFSSTVVEYEYIVAFNGYFTAKARNSFISSALKSSEVDNWRIIPRNNPSSDYPSDFEVIQIKEKQKAGLLTLEDHPNIKRVTPQRKVFRSLKYAESDPTVPCNETRWSQKWQSSRPLRRASLSLGSGFWHATGRHSSRRLLRAIPRQVAQTLQADVLWQMGYTGANVRVAVFDTGLSEKHPHFKNVKERTNWTNERTLDDGLGHGTFVAGVIASMRECQGFAPDAELHIFRVFTNNQVSYTSWFLDAFNYAILKKIDVLNLSIGGPDFMDHPFVDKVWELTANNVIMVSAIGNDGPLYGTLNNPADQMDVIGVGGIDFEDNIARFSSRGMTTWELPGGYGRMKPDIVTYGAGVRGSGVKGGCRALSGTSVASPVVAGAVTLLVSTVQKRELVNPASMKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	NM_003791.3
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003791.3

ORF Insert Sequence:

ATGAAGCTTG TCAACATCTG GCTGCTTCTG CTCGTGGTTT TGCTCTGTGG GAAGAAACAT 
CTGGGCGACA GACTGGAAAA GAAATCTTTT GAAAAGGCCC CATGCCCTGG CTGTTCCCAC 
CTGACTTTGA AGGTGGAATT CTCATCAACA GTTGTGGAAT ATGAATATAT TGTGGCTTTC 
AATGGATACT TTACAGCCAA AGCTAGAAAT TCATTTATTT CAAGTGCCCT GAAGAGCAGT 
GAAGTAGACA ATTGGAGAAT TATACCTCGA AACAATCCAT CCAGTGACTA CCCTAGTGAT 
TTTGAGGTGA TTCAGATAAA AGAAAAACAG AAAGCGGGGC TGCTAACACT TGAAGATCAT 
CCAAACATCA AACGGGTCAC GCCCCAACGA AAAGTCTTTC GTTCCCTCAA GTATGCTGAA 
TCTGACCCCA CAGTACCCTG CAATGAAACC CGGTGGAGCC AGAAGTGGCA ATCATCACGT 
CCCCTGCGAA GAGCCAGCCT CTCCCTGGGC TCTGGCTTCT GGCATGCTAC GGGAAGGCAT 
TCGAGCAGAC GGCTGCTGAG AGCCATCCCG CGCCAGGTTG CCCAGACACT GCAGGCAGAT 
GTGCTCTGGC AGATGGGATA TACAGGTGCT AATGTAAGAG TTGCTGTTTT TGACACTGGG 
CTGAGCGAGA AGCATCCCCA CTTCAAAAAT GTGAAGGAGA GAACCAACTG GACCAACGAG 
CGAACGCTGG ACGATGGGTT GGGCCATGGC ACATTCGTGG CAGGTGTGAT AGCCAGCATG 
AGGGAGTGCC AAGGATTTGC TCCAGATGCA GAACTTCACA TTTTCAGGGT CTTTACCAAT 
AATCAGGTAT CTTACACATC TTGGTTTTTG GACGCCTTCA ACTATGCCAT TTTAAAGAAG 
ATCGACGTGT TAAACCTCAG CATCGGCGGC CCGGACTTCA TGGATCATCC GTTTGTTGAC 
AAGGTGTGGG AATTAACAGC TAACAATGTA ATCATGGTTT CTGCTATTGG CAATGACGGA 
CCTCTTTATG GCACTCTGAA TAACCCTGCT GATCAAATGG ATGTGATTGG AGTAGGCGGC 
ATTGACTTTG AAGATAACAT CGCCCGCTTT TCTTCAAGGG GAATGACTAC CTGGGAGCTA 
CCAGGAGGCT ACGGTCGCAT GAAACCTGAC ATTGTCACCT ATGGTGCTGG CGTGCGGGGT 
TCTGGCGTGA AAGGGGGGTG CCGGGCCCTC TCAGGGACCA GTGTTGCTTC TCCAGTGGTT 
GCAGGTGCTG TCACCTTGTT AGTGAGCACA GTCCAGAAGC GTGAGCTGGT GAATCCCGCC 
AGTATGAAGC AGGCCCTGAT CGCGTCAGCC CGGAGGCTCC CCGGGGTCAA CATGTTTGAG 
CAAGGCCACG GCAAGCTCGA TCTGCTCAGA GCCTATCAGA TCCTCAACAG CTACAAGCCA 
CAGGCAAGTT TGAGCCCCAG CTACATAGAT CTGACTGAGT GTCCCTACAT GTGGCCCTAC 
TGCTCCCAGC CCATCTACTA TGGAGGAATG CCGACAGTTG TTAATGTCAC CATCCTCAAC 
GGCATGGGAG TCACAGGAAG AATTGTAGAT AAGCCTGACT GGCAGCCCTA TTTGCCACAG 
AACGGAGACA ACATTGAAGT TGCCTTCTCC TACTCCTCGG TCTTATGGCC TTGGTCGGGC 
TACCTGGCCA TCTCCATTTC TGTGACCAAG AAAGCGGCTT CCTGGGAAGG CATTGCTCAG 
GGCCATGTCA TGATCACTGT GGCTTCCCCA GCAGAGACAG AGTCAAAAAA TGGTGCAGAA 
CAGACTTCAA CAGTAAAGCT CCCCATTAAG GTGAAGATAA TTCCTACTCC CCCGCGAAGC 
AAGAGAGTTC TCTGGGATCA GTACCACAAC CTCCGCTATC CACCTGGCTA TTTCCCCAGG 
GATAATTTAA GGATGAAGAA TGACCCTTTA GACTGGAATG GTGATCACAT CCACACCAAT 
TTCAGGGATA TGTACCAGCA TCTGAGAAGC ATGGGCTACT TTGTAGAGGT CCTCGGGGCC 
CCCTTCACGT GTTTTGATGC CAGTCAGTAT GGCACTTTGC TGATGGTGGA CAGTGAGGAG 
GAGTACTTCC CTGAAGAGAT CGCCAAGCTC CGGAGGGACG TGGACAACGG CCTCTCGCTC 
GTCATCTTCA GTGACTGGTA CAACACTTCT GTTATGAGAA AAGTGAAGTT TTATGATGAA 
AACACAAGGC AGTGGTGGAT GCCGGATACC GGAGGAGCTA ACATCCCAGC TCTGAATGAG 
CTGCTGTCTG TGTGGAACAT GGGGTTCAGC GATGGCCTGT ATGAAGGGGA GTTCACCCTG 
GCCAACCATG ACATGTATTA TGCGTCAGGG TGCAGCATCG CGAAGTTTCC AGAAGATGGC 
GTCGTGATAA CACAGACTTT CAAGGACCAA GGATTGGAGG TTTTAAAGCA GGAAACAGCA 
GTTGTTGAAA ACGTCCCCAT TTTGGGACTT TATCAGATTC CAGCTGAGGG TGGAGGCCGG 
ATTGTACTGT ATGGGGACTC CAATTGCTTG GATGACAGTC ACCGACAGAA GGACTGCTTT 
TGGCTTCTGG ATGCCCTCCT CCAGTACACA TCGTATGGGG TGACACCGCC TAGCCTCAGT 
CACTCTGGGA ACCGCCAGCG CCCTCCCAGT GGAGCAGGCT CAGTCACTCC AGAGAGGATG 
GAAGGAAACC ATCTTCATCG GTACTCCAAG GTTCTGGAGG CCCATTTGGG AGACCCAAAA 
CCTCGGCCTC TACCAGCCTG TCCACGCTTG TCTTGGGCCA AGCCACAGCC TTTAAACGAG 
ACGGCGCCCA GTAACCTTTG GAAACATCAG AAGCTACTCT CCATTGACCT GGACAAGGTG 
GTGTTACCCA ACTTTCGATC GAATCGCCCT CAAGTGAGGC CCTTGTCCCC TGGAGAGAGC 
GGCGCCTGGG ACATTCCTGG AGGGATCATG CCTGGCCGCT ACAACCAGGA GGTGGGCCAG 
ACCATTCCTG TCTTTGCCTT CCTGGGAGCC ATGGTGGTCC TGGCCTTCTT TGTGGTACAA 
ATCAACAAGG CCAAGAGCAG GCCGAAGCGG AGGAAGCCCA GGGTGAAGCG CCCGCAGCTC 
ATGCAGCAGG TTCACCCGCC AAAGACCCCT TCGGTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( XM_017023816.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879305.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.

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CloneID	OHu86335
Clone ID Related Accession (Same CDS sequence)	XM_017023816.1 , XM_017023816.2
Accession Version	XM_017023816.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCAGG CCCTGATCGC GTCAGCCCGG AGGCTCCCCG GGGTCAACAT GTTTGAGCAA 
GGCCACGGCA AGCTCGATCT GCTCAGAGCC TATCAGATCC TCAACAGCTA CAAGCCACAG 
GCAAGTTTGA GCCCCAGCTA CATAGATCTG ACTGAGTGTC CCTACATGTG GCCCTACTGC 
TCCCAGCCCA TCTACTATGG AGGAATGCCG ACAGTTGTTA ATGTCACCAT CCTCAACGGC 
ATGGGAGTCA CAGGAAGAAT TGTAGATAAG CCTGACTGGC AGCCCTATTT GCCACAGAAC 
GGAGACAACA TTGAAGTTGC CTTCTCCTAC TCCTCGGTCT TATGGCCTTG GTCGGGCTAC 
CTGGCCATCT CCATTTCTGT GACCAAGAAA GCGGCTTCCT GGGAAGGCAT TGCTCAGGGC 
CATGTCATGA TCACTGTGGC TTCCCCAGCA GAGACAGAGT CAAAAAATGG TGCAGAACAG 
ACTTCAACAG TAAAGCTCCC CATTAAGGTG AAGATAATTC CTACTCCCCC GCGAAGCAAG 
AGAGTTCTCT GGGATCAGTA CCACAACCTC CGCTATCCAC CTGGCTATTT CCCCAGGGAT 
AATTTAAGGA TGAAGAATGA CCCTTTAGAC TGGAATGGTG ATCACATCCA CACCAATTTC 
AGGGATATGT ACCAGCATCT GAGAAGCATG GGCTACTTTG TAGAGGTCCT CGGGGCCCCC 
TTCACGTGTT TTGATGCCAG TCAGTATGGC ACTTTGCTGA TGGTGGACAG TGAGGAGGAG 
TACTTCCCTG AAGAGATCGC CAAGCTCCGG AGGGACGTGG ACAACGGCCT CTCGCTCGTC 
ATCTTCAGTG ACTGGTACAA CACTTCTGTT ATGAGAAAAG TGAAGTTTTA TGATGAAAAC 
ACAAGGCAGT GGTGGATGCC GGATACCGGA GGAGCTAACA TCCCAGCTCT GAATGAGCTG 
CTGTCTGTGT GGAACATGGG GTTCAGCGAT GGCCTGTATG AAGGGGAGTT CACCCTGGCC 
AACCATGACA TGTATTATGC GTCAGGGTGC AGCATCGCGA AGTTTCCAGA AGATGGCGTC 
GTGATAACAC AGACTTTCAA GGACCAAGGA TTGGAGGTTT TAAAGCAGGA AACAGCAGTT 
GTTGAAAACG TCCCCATTTT GGGACTTTAT CAGATTCCAG CTGAGGGTGG AGGCCGGATT 
GTACTGTATG GGGACTCCAA TTGCTTGGAT GACAGTCACC GACAGAAGGA CTGCTTTTGG 
CTTCTGGATG CCCTCCTCCA GTACACATCG TATGGGGTGA CACCGCCTAG CCTCAGTCAC 
TCTGGGAACC GCCAGCGCCC TCCCAGTGGA GCAGGCTCAG TCACTCCAGA GAGGATGGAA 
GGAAACCATC TTCATCGGTA CTCCAAGGTT CTGGAGGCCC ATTTGGGAGA CCCAAAACCT 
CGGCCTCTAC CAGCCTGTCC ACGCTTGTCT TGGGCCAAGC CACAGCCTTT AAACGAGACG 
GCGCCCAGTA ACCTTTGGAA ACATCAGAAG CTACTCTCCA TTGACCTGGA CAAGGTGGTG 
TTACCCAACT TTCGATCGAA TCGCCCTCAA GTGAGGCCCT TGTCCCCTGG AGAGAGCGGC 
GCCTGGGACA TTCCTGGAGG GATCATGCCT GGCCGCTACA ACCAGGAGGT GGGCCAGACC 
ATTCCTGTCT TTGCCTTCCT GGGAGCCATG GTGGTCCTGG CCTTCTTTGT GGTACAAATC 
AACAAGGCCA AGAGCAGGCC GAAGCGGAGG AAGCCCAGGG TGAAGCGCCC GCAGCTCATG 
CAGCAGGTTC ACCCGCCAAA GACCCCTTCG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879305.1
CDS	1606..3441
Translation	MKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	XM_017023816.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023816.1

ORF Insert Sequence:

ATGAAGCAGG CCCTGATCGC GTCAGCCCGG AGGCTCCCCG GGGTCAACAT GTTTGAGCAA 
GGCCACGGCA AGCTCGATCT GCTCAGAGCC TATCAGATCC TCAACAGCTA CAAGCCACAG 
GCAAGTTTGA GCCCCAGCTA CATAGATCTG ACTGAGTGTC CCTACATGTG GCCCTACTGC 
TCCCAGCCCA TCTACTATGG AGGAATGCCG ACAGTTGTTA ATGTCACCAT CCTCAACGGC 
ATGGGAGTCA CAGGAAGAAT TGTAGATAAG CCTGACTGGC AGCCCTATTT GCCACAGAAC 
GGAGACAACA TTGAAGTTGC CTTCTCCTAC TCCTCGGTCT TATGGCCTTG GTCGGGCTAC 
CTGGCCATCT CCATTTCTGT GACCAAGAAA GCGGCTTCCT GGGAAGGCAT TGCTCAGGGC 
CATGTCATGA TCACTGTGGC TTCCCCAGCA GAGACAGAGT CAAAAAATGG TGCAGAACAG 
ACTTCAACAG TAAAGCTCCC CATTAAGGTG AAGATAATTC CTACTCCCCC GCGAAGCAAG 
AGAGTTCTCT GGGATCAGTA CCACAACCTC CGCTATCCAC CTGGCTATTT CCCCAGGGAT 
AATTTAAGGA TGAAGAATGA CCCTTTAGAC TGGAATGGTG ATCACATCCA CACCAATTTC 
AGGGATATGT ACCAGCATCT GAGAAGCATG GGCTACTTTG TAGAGGTCCT CGGGGCCCCC 
TTCACGTGTT TTGATGCCAG TCAGTATGGC ACTTTGCTGA TGGTGGACAG TGAGGAGGAG 
TACTTCCCTG AAGAGATCGC CAAGCTCCGG AGGGACGTGG ACAACGGCCT CTCGCTCGTC 
ATCTTCAGTG ACTGGTACAA CACTTCTGTT ATGAGAAAAG TGAAGTTTTA TGATGAAAAC 
ACAAGGCAGT GGTGGATGCC GGATACCGGA GGAGCTAACA TCCCAGCTCT GAATGAGCTG 
CTGTCTGTGT GGAACATGGG GTTCAGCGAT GGCCTGTATG AAGGGGAGTT CACCCTGGCC 
AACCATGACA TGTATTATGC GTCAGGGTGC AGCATCGCGA AGTTTCCAGA AGATGGCGTC 
GTGATAACAC AGACTTTCAA GGACCAAGGA TTGGAGGTTT TAAAGCAGGA AACAGCAGTT 
GTTGAAAACG TCCCCATTTT GGGACTTTAT CAGATTCCAG CTGAGGGTGG AGGCCGGATT 
GTACTGTATG GGGACTCCAA TTGCTTGGAT GACAGTCACC GACAGAAGGA CTGCTTTTGG 
CTTCTGGATG CCCTCCTCCA GTACACATCG TATGGGGTGA CACCGCCTAG CCTCAGTCAC 
TCTGGGAACC GCCAGCGCCC TCCCAGTGGA GCAGGCTCAG TCACTCCAGA GAGGATGGAA 
GGAAACCATC TTCATCGGTA CTCCAAGGTT CTGGAGGCCC ATTTGGGAGA CCCAAAACCT 
CGGCCTCTAC CAGCCTGTCC ACGCTTGTCT TGGGCCAAGC CACAGCCTTT AAACGAGACG 
GCGCCCAGTA ACCTTTGGAA ACATCAGAAG CTACTCTCCA TTGACCTGGA CAAGGTGGTG 
TTACCCAACT TTCGATCGAA TCGCCCTCAA GTGAGGCCCT TGTCCCCTGG AGAGAGCGGC 
GCCTGGGACA TTCCTGGAGG GATCATGCCT GGCCGCTACA ACCAGGAGGT GGGCCAGACC 
ATTCCTGTCT TTGCCTTCCT GGGAGCCATG GTGGTCCTGG CCTTCTTTGT GGTACAAATC 
AACAAGGCCA AGAGCAGGCC GAAGCGGAGG AAGCCCAGGG TGAAGCGCCC GCAGCTCATG 
CAGCAGGTTC ACCCGCCAAA GACCCCTTCG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( XM_017023816.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879305.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu86335
Clone ID Related Accession (Same CDS sequence)	XM_017023816.1 , XM_017023816.2
Accession Version	XM_017023816.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1836bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017023816.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAAGCAGG CCCTGATCGC GTCAGCCCGG AGGCTCCCCG GGGTCAACAT GTTTGAGCAA 
GGCCACGGCA AGCTCGATCT GCTCAGAGCC TATCAGATCC TCAACAGCTA CAAGCCACAG 
GCAAGTTTGA GCCCCAGCTA CATAGATCTG ACTGAGTGTC CCTACATGTG GCCCTACTGC 
TCCCAGCCCA TCTACTATGG AGGAATGCCG ACAGTTGTTA ATGTCACCAT CCTCAACGGC 
ATGGGAGTCA CAGGAAGAAT TGTAGATAAG CCTGACTGGC AGCCCTATTT GCCACAGAAC 
GGAGACAACA TTGAAGTTGC CTTCTCCTAC TCCTCGGTCT TATGGCCTTG GTCGGGCTAC 
CTGGCCATCT CCATTTCTGT GACCAAGAAA GCGGCTTCCT GGGAAGGCAT TGCTCAGGGC 
CATGTCATGA TCACTGTGGC TTCCCCAGCA GAGACAGAGT CAAAAAATGG TGCAGAACAG 
ACTTCAACAG TAAAGCTCCC CATTAAGGTG AAGATAATTC CTACTCCCCC GCGAAGCAAG 
AGAGTTCTCT GGGATCAGTA CCACAACCTC CGCTATCCAC CTGGCTATTT CCCCAGGGAT 
AATTTAAGGA TGAAGAATGA CCCTTTAGAC TGGAATGGTG ATCACATCCA CACCAATTTC 
AGGGATATGT ACCAGCATCT GAGAAGCATG GGCTACTTTG TAGAGGTCCT CGGGGCCCCC 
TTCACGTGTT TTGATGCCAG TCAGTATGGC ACTTTGCTGA TGGTGGACAG TGAGGAGGAG 
TACTTCCCTG AAGAGATCGC CAAGCTCCGG AGGGACGTGG ACAACGGCCT CTCGCTCGTC 
ATCTTCAGTG ACTGGTACAA CACTTCTGTT ATGAGAAAAG TGAAGTTTTA TGATGAAAAC 
ACAAGGCAGT GGTGGATGCC GGATACCGGA GGAGCTAACA TCCCAGCTCT GAATGAGCTG 
CTGTCTGTGT GGAACATGGG GTTCAGCGAT GGCCTGTATG AAGGGGAGTT CACCCTGGCC 
AACCATGACA TGTATTATGC GTCAGGGTGC AGCATCGCGA AGTTTCCAGA AGATGGCGTC 
GTGATAACAC AGACTTTCAA GGACCAAGGA TTGGAGGTTT TAAAGCAGGA AACAGCAGTT 
GTTGAAAACG TCCCCATTTT GGGACTTTAT CAGATTCCAG CTGAGGGTGG AGGCCGGATT 
GTACTGTATG GGGACTCCAA TTGCTTGGAT GACAGTCACC GACAGAAGGA CTGCTTTTGG 
CTTCTGGATG CCCTCCTCCA GTACACATCG TATGGGGTGA CACCGCCTAG CCTCAGTCAC 
TCTGGGAACC GCCAGCGCCC TCCCAGTGGA GCAGGCTCAG TCACTCCAGA GAGGATGGAA 
GGAAACCATC TTCATCGGTA CTCCAAGGTT CTGGAGGCCC ATTTGGGAGA CCCAAAACCT 
CGGCCTCTAC CAGCCTGTCC ACGCTTGTCT TGGGCCAAGC CACAGCCTTT AAACGAGACG 
GCGCCCAGTA ACCTTTGGAA ACATCAGAAG CTACTCTCCA TTGACCTGGA CAAGGTGGTG 
TTACCCAACT TTCGATCGAA TCGCCCTCAA GTGAGGCCCT TGTCCCCTGG AGAGAGCGGC 
GCCTGGGACA TTCCTGGAGG GATCATGCCT GGCCGCTACA ACCAGGAGGT GGGCCAGACC 
ATTCCTGTCT TTGCCTTCCT GGGAGCCATG GTGGTCCTGG CCTTCTTTGT GGTACAAATC 
AACAAGGCCA AGAGCAGGCC GAAGCGGAGG AAGCCCAGGG TGAAGCGCCC GCAGCTCATG 
CAGCAGGTTC ACCCGCCAAA GACCCCTTCG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879305.1
CDS	1597..3432
Translation	MKQALIASARRLPGVNMFEQGHGKLDLLRAYQILNSYKPQASLSPSYIDLTECPYMWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	XM_017023816.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023816.2

ORF Insert Sequence:

ATGAAGCAGG CCCTGATCGC GTCAGCCCGG AGGCTCCCCG GGGTCAACAT GTTTGAGCAA 
GGCCACGGCA AGCTCGATCT GCTCAGAGCC TATCAGATCC TCAACAGCTA CAAGCCACAG 
GCAAGTTTGA GCCCCAGCTA CATAGATCTG ACTGAGTGTC CCTACATGTG GCCCTACTGC 
TCCCAGCCCA TCTACTATGG AGGAATGCCG ACAGTTGTTA ATGTCACCAT CCTCAACGGC 
ATGGGAGTCA CAGGAAGAAT TGTAGATAAG CCTGACTGGC AGCCCTATTT GCCACAGAAC 
GGAGACAACA TTGAAGTTGC CTTCTCCTAC TCCTCGGTCT TATGGCCTTG GTCGGGCTAC 
CTGGCCATCT CCATTTCTGT GACCAAGAAA GCGGCTTCCT GGGAAGGCAT TGCTCAGGGC 
CATGTCATGA TCACTGTGGC TTCCCCAGCA GAGACAGAGT CAAAAAATGG TGCAGAACAG 
ACTTCAACAG TAAAGCTCCC CATTAAGGTG AAGATAATTC CTACTCCCCC GCGAAGCAAG 
AGAGTTCTCT GGGATCAGTA CCACAACCTC CGCTATCCAC CTGGCTATTT CCCCAGGGAT 
AATTTAAGGA TGAAGAATGA CCCTTTAGAC TGGAATGGTG ATCACATCCA CACCAATTTC 
AGGGATATGT ACCAGCATCT GAGAAGCATG GGCTACTTTG TAGAGGTCCT CGGGGCCCCC 
TTCACGTGTT TTGATGCCAG TCAGTATGGC ACTTTGCTGA TGGTGGACAG TGAGGAGGAG 
TACTTCCCTG AAGAGATCGC CAAGCTCCGG AGGGACGTGG ACAACGGCCT CTCGCTCGTC 
ATCTTCAGTG ACTGGTACAA CACTTCTGTT ATGAGAAAAG TGAAGTTTTA TGATGAAAAC 
ACAAGGCAGT GGTGGATGCC GGATACCGGA GGAGCTAACA TCCCAGCTCT GAATGAGCTG 
CTGTCTGTGT GGAACATGGG GTTCAGCGAT GGCCTGTATG AAGGGGAGTT CACCCTGGCC 
AACCATGACA TGTATTATGC GTCAGGGTGC AGCATCGCGA AGTTTCCAGA AGATGGCGTC 
GTGATAACAC AGACTTTCAA GGACCAAGGA TTGGAGGTTT TAAAGCAGGA AACAGCAGTT 
GTTGAAAACG TCCCCATTTT GGGACTTTAT CAGATTCCAG CTGAGGGTGG AGGCCGGATT 
GTACTGTATG GGGACTCCAA TTGCTTGGAT GACAGTCACC GACAGAAGGA CTGCTTTTGG 
CTTCTGGATG CCCTCCTCCA GTACACATCG TATGGGGTGA CACCGCCTAG CCTCAGTCAC 
TCTGGGAACC GCCAGCGCCC TCCCAGTGGA GCAGGCTCAG TCACTCCAGA GAGGATGGAA 
GGAAACCATC TTCATCGGTA CTCCAAGGTT CTGGAGGCCC ATTTGGGAGA CCCAAAACCT 
CGGCCTCTAC CAGCCTGTCC ACGCTTGTCT TGGGCCAAGC CACAGCCTTT AAACGAGACG 
GCGCCCAGTA ACCTTTGGAA ACATCAGAAG CTACTCTCCA TTGACCTGGA CAAGGTGGTG 
TTACCCAACT TTCGATCGAA TCGCCCTCAA GTGAGGCCCT TGTCCCCTGG AGAGAGCGGC 
GCCTGGGACA TTCCTGGAGG GATCATGCCT GGCCGCTACA ACCAGGAGGT GGGCCAGACC 
ATTCCTGTCT TTGCCTTCCT GGGAGCCATG GTGGTCCTGG CCTTCTTTGT GGTACAAATC 
AACAAGGCCA AGAGCAGGCC GAAGCGGAGG AAGCCCAGGG TGAAGCGCCC GCAGCTCATG 
CAGCAGGTTC ACCCGCCAAA GACCCCTTCG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( XM_017023817.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879306.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu86336
Clone ID Related Accession (Same CDS sequence)	XM_017023817.2 , XM_017023817.1 , XM_024450477.1
Accession Version	XM_017023817.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017023817.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879306.1
CDS	2016..3686
Translation	MWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	XM_017023817.2
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023817.2

ORF Insert Sequence:

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( XM_017023817.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016879306.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu86336
Clone ID Related Accession (Same CDS sequence)	XM_017023817.2 , XM_017023817.1 , XM_024450477.1
Accession Version	XM_017023817.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016879306.1
CDS	2025..3695
Translation	MWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	XM_017023817.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017023817.1

ORF Insert Sequence:

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

MBTPS1 ( XM_024450477.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024306245.1 Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu86336
Clone ID Related Accession (Same CDS sequence)	XM_017023817.2 , XM_017023817.1 , XM_024450477.1
Accession Version	XM_024450477.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	membrane-bound transcription factor site-1 protease isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024306245.1
CDS	2829..4499
Translation	MWPYCSQPIYYGGMPTVVNVTILNGMGVTGRIVDKPDWQPYLPQNGDNIEVAFSYSSVLWPWSGYLAISISVTKKAASWEGIAQGHVMITVASPAETESKNGAEQTSTVKLPIKVKIIPTPPRSKRVLWDQYHNLRYPPGYFPRDNLRMKNDPLDWNGDHIHTNFRDMYQHLRSMGYFVEVLGAPFTCFDASQYGTLLMVDSEEEYFPEEIAKLRRDVDNGLSLVIFSDWYNTSVMRKVKFYDENTRQWWMPDTGGANIPALNELLSVWNMGFSDGLYEGEFTLANHDMYYASGCSIAKFPEDGVVITQTFKDQGLEVLKQETAVVENVPILGLYQIPAEGGGRIVLYGDSNCLDDSHRQKDCFWLLDALLQYTSYGVTPPSLSHSGNRQRPPSGAGSVTPERMEGNHLHRYSKVLEAHLGDPKPRPLPACPRLSWAKPQPLNETAPSNLWKHQKLLSIDLDKVVLPNFRSNRPQVRPLSPGESGAWDIPGGIMPGRYNQEVGQTIPVFAFLGAMVVLAFFVVQINKAKSRPKRRKPRVKRPQLMQQVHPPKTPSV

Target ORF information:

RefSeq Version	XM_024450477.1
Organism	Homo sapiens(human)
Definition	Homo sapiens membrane bound transcription factor peptidase, site 1 (MBTPS1), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024450477.1

ORF Insert Sequence:

ATGTGGCCCT ACTGCTCCCA GCCCATCTAC TATGGAGGAA TGCCGACAGT TGTTAATGTC 
ACCATCCTCA ACGGCATGGG AGTCACAGGA AGAATTGTAG ATAAGCCTGA CTGGCAGCCC 
TATTTGCCAC AGAACGGAGA CAACATTGAA GTTGCCTTCT CCTACTCCTC GGTCTTATGG 
CCTTGGTCGG GCTACCTGGC CATCTCCATT TCTGTGACCA AGAAAGCGGC TTCCTGGGAA 
GGCATTGCTC AGGGCCATGT CATGATCACT GTGGCTTCCC CAGCAGAGAC AGAGTCAAAA 
AATGGTGCAG AACAGACTTC AACAGTAAAG CTCCCCATTA AGGTGAAGAT AATTCCTACT 
CCCCCGCGAA GCAAGAGAGT TCTCTGGGAT CAGTACCACA ACCTCCGCTA TCCACCTGGC 
TATTTCCCCA GGGATAATTT AAGGATGAAG AATGACCCTT TAGACTGGAA TGGTGATCAC 
ATCCACACCA ATTTCAGGGA TATGTACCAG CATCTGAGAA GCATGGGCTA CTTTGTAGAG 
GTCCTCGGGG CCCCCTTCAC GTGTTTTGAT GCCAGTCAGT ATGGCACTTT GCTGATGGTG 
GACAGTGAGG AGGAGTACTT CCCTGAAGAG ATCGCCAAGC TCCGGAGGGA CGTGGACAAC 
GGCCTCTCGC TCGTCATCTT CAGTGACTGG TACAACACTT CTGTTATGAG AAAAGTGAAG 
TTTTATGATG AAAACACAAG GCAGTGGTGG ATGCCGGATA CCGGAGGAGC TAACATCCCA 
GCTCTGAATG AGCTGCTGTC TGTGTGGAAC ATGGGGTTCA GCGATGGCCT GTATGAAGGG 
GAGTTCACCC TGGCCAACCA TGACATGTAT TATGCGTCAG GGTGCAGCAT CGCGAAGTTT 
CCAGAAGATG GCGTCGTGAT AACACAGACT TTCAAGGACC AAGGATTGGA GGTTTTAAAG 
CAGGAAACAG CAGTTGTTGA AAACGTCCCC ATTTTGGGAC TTTATCAGAT TCCAGCTGAG 
GGTGGAGGCC GGATTGTACT GTATGGGGAC TCCAATTGCT TGGATGACAG TCACCGACAG 
AAGGACTGCT TTTGGCTTCT GGATGCCCTC CTCCAGTACA CATCGTATGG GGTGACACCG 
CCTAGCCTCA GTCACTCTGG GAACCGCCAG CGCCCTCCCA GTGGAGCAGG CTCAGTCACT 
CCAGAGAGGA TGGAAGGAAA CCATCTTCAT CGGTACTCCA AGGTTCTGGA GGCCCATTTG 
GGAGACCCAA AACCTCGGCC TCTACCAGCC TGTCCACGCT TGTCTTGGGC CAAGCCACAG 
CCTTTAAACG AGACGGCGCC CAGTAACCTT TGGAAACATC AGAAGCTACT CTCCATTGAC 
CTGGACAAGG TGGTGTTACC CAACTTTCGA TCGAATCGCC CTCAAGTGAG GCCCTTGTCC 
CCTGGAGAGA GCGGCGCCTG GGACATTCCT GGAGGGATCA TGCCTGGCCG CTACAACCAG 
GAGGTGGGCC AGACCATTCC TGTCTTTGCC TTCCTGGGAG CCATGGTGGT CCTGGCCTTC 
TTTGTGGTAC AAATCAACAA GGCCAAGAGC AGGCCGAAGC GGAGGAAGCC CAGGGTGAAG 
CGCCCGCAGC TCATGCAGCA GGTTCACCCG CCAAAGACCC CTTCGGTGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genetics of the human face: Identification of large-effect single gene variants.
Proceedings of the National Academy of Sciences of the United States of America(2018 Jan)
Crouch DJM,Winney B,Koppen WP,Christmas WJ,Hutnik K,Day T,Meena D,Boumertit A,Hysi P,Nessa A,Spector TD,Kittler J,Bodmer WF

Site-1 protease and lysosomal homeostasis.
Biochimica et biophysica acta1864(11 Pt B)2162-2168(2017 11)
Velho RV,De Pace R,Kl?nder S,Di Lorenzo G,Schweizer M,Braulke T,Pohl S

Site-1 protease is required for the generation of soluble (pro)renin receptor.
Journal of biochemistry161(4)369-379(2017 Apr)
Nakagawa T,Suzuki-Nakagawa C,Watanabe A,Asami E,Matsumoto M,Nakano M,Ebihara A,Uddin MN,Suzuki F

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MBTPS1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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