TNFRSF25 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TNFRSF25
Entrez Gene ID	8718
Full Name	TNF receptor superfamily member 25
Synonyms	APO-3,DDR3,DR3,LARD,TNFRSF12,TR3,TRAMP,WSL-1,WSL-LR
General protein information	Preferred Names TNF receptor superfamily member 25 Names tumor necrosis factor receptor superfamily member 25 apoptosis inducing receptor apoptosis-inducing receptor AIR apoptosis-mediating receptor DR3 apoptosis-mediating receptor TRAMP death domain receptor 3 soluble form death receptor beta lymphocyte-associated receptor of death protein WSL-1 tumor necrosis factor receptor superfamily, member 12 (translocating chain-association membrane protein)
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p36.31
Summary	The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed preferentially in the tissues enriched in lymphocytes, and it may play a role in regulating lymphocyte homeostasis. This receptor has been shown to stimulate NF-kappa B activity and regulate cell apoptosis. The signal transduction of this receptor is mediated by various death domain containing adaptor proteins. Knockout studies in mice suggested the role of this gene in the removal of self-reactive T cells in the thymus. Multiple alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported, most of which are potentially secreted molecules. The alternative splicing of this gene in B and T cells encounters a programmed change upon T-cell activation, which predominantly produces full-length, membrane bound isoforms, and is thought to be involved in controlling lymphocyte proliferation induced by T-cell activation. [provided by RefSeq, Jul 2008].
Disorder MIM:	603366

mRNA and Protein(s)

mRNA	Protein	Name
NM_148967.1	NP_683868.1	tumor necrosis factor receptor superfamily member 25 isoform 4 precursor
NM_003790.2	NP_003781.1	tumor necrosis factor receptor superfamily member 25 isoform 2 precursor
NM_148970.1	NP_683871.1	tumor necrosis factor receptor superfamily member 25 isoform 7 precursor
NM_148965.1	NP_683866.1	tumor necrosis factor receptor superfamily member 25 isoform 1 precursor
NM_148966.1	NP_683867.1	tumor necrosis factor receptor superfamily member 25 isoform 3 precursor
NM_001039664.1	NP_001034753.1	tumor necrosis factor receptor superfamily member 25 isoform 12 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	TNFRSF25	NP_683866.1
Pan troglodytes (chimpanzee)	TNFRSF25	XP_001165991.1
	TNFRSF25	XP_001093543.2
Canis lupus familiaris (dog)	TNFRSF25	XP_005620523.1
Gallus gallus (chicken)	TNFRSF25	XP_423315.4
Bos taurus (cattle)	TNFRSF25	NP_001137549.1
Rattus norvegicus (Norway rat)	Tnfrsf25	NP_001131116.1
Mus musculus (house mouse)	Tnfrsf25	NP_149031.2

Gene Ontology
Bibliography

Related articles in PubMed

DNA methylation polymerase chain reaction (PCR) array of apoptosis-related genes in pleomorphic adenomas of the salivary glands.
Pereira NB, do Carmo ACM, Campos K, Costa SFDS, Diniz MG, Gomez RS, Gomes CC
Oral surgery, oral medicine, oral pathology and oral radiology124(6)554-560(2017 Dec)

CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss.
Collins FL, Williams JO, Bloom AC, Singh RK, Jordan L, Stone MD, McCabe LR, Wang ECY, Williams AS
Bone9794-104(2017 04)

Death receptor 3 signaling enhances proliferation of human regulatory T cells.
Bittner S, Knoll G, Ehrenschwender M
FEBS letters591(8)1187-1195(2017 04)

Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells.
Bamias G, Filidou E, Goukos D, Valatas V, Arvanitidis K, Panagopoulou M, Kouklakis G, Daikos GL, Ladas SD, Kolios G
Translational research : the journal of laboratory and clinical medicine180118-130.e2(2017 Feb)

DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.
Filatova EN, Anisenkova EV, Presnyakova NB, Utkin OV
Acta microbiologica et immunologica Hungarica63(3)339-357(2016 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

the DR3/TL1A pathway directly enhances human OC formation and resorptive activity, controlling expression and activation of CCL3 and MMP-9.
Title: CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss.

Data suggest that human regulatory T-lymphocytes express DR3 and demonstrate DR3/TL1A-mediated activation of signaling via MAP kinases and NFkappaB. (DR3 = death receptor 3; TL1A/TNFSF15 = tumor necrosis factor [ligand] superfamily, member 15)
Title: Death receptor 3 signaling enhances proliferation of human regulatory T cells.

In addition to apoptosis, DR3 can robustly trigger necroptotic cell death and provide evidence for TL1A-induced, DR3-mediated necrosome assembly. DR3-mediated necroptosis critically depends on receptor-interacting protein 1 (RIP1) and RIP3, the core components of the necroptotic machinery, which activate the pseudo-kinase mixed lineage kinase domain-like, the prototypic downstream effector molecule of necroptosis.
Title: Death receptor 3 mediates necroptotic cell death.

These results raise the possibility for involvement of TL1A/DR3/DR3-mediated mechanisms in epithelial-mesenchymal interactions and the development of inflammation-induced intestinal fibrosis in Crohn's disease.
Title: Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells.

Activation of DR3 is accompanied by inhibition of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.
Title: DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.

The following TNFRSF25 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TNFRSF25 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu25555	NM_001039664.1 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 12, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu26884	NM_003790.2 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu27208	NM_148965.1 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$179.50-$251.30 $359.00
OHu26611	NM_148967.1 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu27008	NM_148966.1 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$265.30 $379.00
OHu27342	NM_148970.1 Latest version!	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$188.30 $269.00

ORF Online Only Promotion

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TNFRSF25 ( NM_001039664.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034753.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 12, mRNA.

Price & Availability↑

CloneID	OHu25555
Clone ID Related Accession (Same CDS sequence)	NM_001039664.1
Accession Version	NM_001039664.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 12 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358309.1 and U83598.1. Transcript Variant: This variant (12) lacks several 3' exons and has an alternate 3' end, when compared to variant 1. The resulting isoform (12) has a distinct and shorter C-terminus, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U94512.1, U83598.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034753.1
CDS	89..634
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPT

Target ORF information:

RefSeq Version	NM_001039664.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 12, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039664.1

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF25 ( NM_003790.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003781.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26884
Clone ID Related Accession (Same CDS sequence)	NM_003790.2
Accession Version	NM_003790.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1254bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from U74611.1 and BM666370.1. On Sep 19, 2002 this sequence version replaced NM_003790.1. Transcript Variant: This variant (2) lacks two coding segments, both of which result in a frameshift, when compared to variant 1. The resulting isoform (2) has a shorter and distinct internal region, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U74611.1, AY358309.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG TCTGTGGCTG GAGGCAGATG 
TTCTGGGTCC AGGTGCTCCT GGCTGGCCTT GTGGTCCCCC TCCTGCTTGG GGCCACCCTG 
ACCTACACAT ACCGCCACTG CTGGCCTCAC AAGCCCCTGG TTACTGCAGA TGAAGCTGGG 
ATGGAGGCTC TGACCCCACC ACCGGCCACC CATCTGTCAC CCTTGGACAG CGCCCACACC 
CTTCTAGCAC CTCCTGACAG CAGTGAGAAG ATCTGCACCG TCCAGTTGGT GGGTAACAGC 
TGGACCCCTG GCTACCCCGA GACCCAGGAG GCGCTCTGCC CGCAGGTGAC ATGGTCCTGG 
GACCAGTTGC CCAGCAGAGC TCTTGGCCCC GCTGCTGCGC CCACACTCTC GCCAGAGTCC 
CCAGCCGGCT CGCCAGCCAT GATGCTGCAG CCGGGCCCGC AGCTCTACGA CGTGATGGAC 
GCGGTCCCAG CGCGGCGCTG GAAGGAGTTC GTGCGCACGC TGGGGCTGCG CGAGGCAGAG 
ATCGAAGCCG TGGAGGTGGA GATCGGCCGC TTCCGAGACC AGCAGTACGA GATGCTCAAG 
CGCTGGCGCC AGCAGCAGCC CGCGGGCCTC GGAGCCGTTT ACGCGGCCCT GGAGCGCATG 
GGGCTGGACG GCTGCGTGGA AGACTTGCGC AGCCGCCTGC AGCGCGGCCC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003781.1
CDS	89..1342
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP

Target ORF information:

RefSeq Version	NM_003790.2
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003790.2

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG TCTGTGGCTG GAGGCAGATG 
TTCTGGGTCC AGGTGCTCCT GGCTGGCCTT GTGGTCCCCC TCCTGCTTGG GGCCACCCTG 
ACCTACACAT ACCGCCACTG CTGGCCTCAC AAGCCCCTGG TTACTGCAGA TGAAGCTGGG 
ATGGAGGCTC TGACCCCACC ACCGGCCACC CATCTGTCAC CCTTGGACAG CGCCCACACC 
CTTCTAGCAC CTCCTGACAG CAGTGAGAAG ATCTGCACCG TCCAGTTGGT GGGTAACAGC 
TGGACCCCTG GCTACCCCGA GACCCAGGAG GCGCTCTGCC CGCAGGTGAC ATGGTCCTGG 
GACCAGTTGC CCAGCAGAGC TCTTGGCCCC GCTGCTGCGC CCACACTCTC GCCAGAGTCC 
CCAGCCGGCT CGCCAGCCAT GATGCTGCAG CCGGGCCCGC AGCTCTACGA CGTGATGGAC 
GCGGTCCCAG CGCGGCGCTG GAAGGAGTTC GTGCGCACGC TGGGGCTGCG CGAGGCAGAG 
ATCGAAGCCG TGGAGGTGGA GATCGGCCGC TTCCGAGACC AGCAGTACGA GATGCTCAAG 
CGCTGGCGCC AGCAGCAGCC CGCGGGCCTC GGAGCCGTTT ACGCGGCCCT GGAGCGCATG 
GGGCTGGACG GCTGCGTGGA AGACTTGCGC AGCCGCCTGC AGCGCGGCCC GTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF25 ( NM_148965.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_683866.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu27208
Clone ID Related Accession (Same CDS sequence)	NM_148965.1
Accession Version	NM_148965.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1281bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358309.1, AF026070.1, BC143886.1 and BM666370.1. This sequence is a reference standard in the RefSeqGene project. Transcript Variant: This variant (1) encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF026070.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGCCACCCC CGTCCCTTGC AGGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG 
TCTGTGGCTG GAGGCAGAGT AGGTGTGTTC TGGGTCCAGG TGCTCCTGGC TGGCCTTGTG 
GTCCCCCTCC TGCTTGGGGC CACCCTGACC TACACATACC GCCACTGCTG GCCTCACAAG 
CCCCTGGTTA CTGCAGATGA AGCTGGGATG GAGGCTCTGA CCCCACCACC GGCCACCCAT 
CTGTCACCCT TGGACAGCGC CCACACCCTT CTAGCACCTC CTGACAGCAG TGAGAAGATC 
TGCACCGTCC AGTTGGTGGG TAACAGCTGG ACCCCTGGCT ACCCCGAGAC CCAGGAGGCG 
CTCTGCCCGC AGGTGACATG GTCCTGGGAC CAGTTGCCCA GCAGAGCTCT TGGCCCCGCT 
GCTGCGCCCA CACTCTCGCC AGAGTCCCCA GCCGGCTCGC CAGCCATGAT GCTGCAGCCG 
GGCCCGCAGC TCTACGACGT GATGGACGCG GTCCCAGCGC GGCGCTGGAA GGAGTTCGTG 
CGCACGCTGG GGCTGCGCGA GGCAGAGATC GAAGCCGTGG AGGTGGAGAT CGGCCGCTTC 
CGAGACCAGC AGTACGAGAT GCTCAAGCGC TGGCGCCAGC AGCAGCCCGC GGGCCTCGGA 
GCCGTTTACG CGGCCCTGGA GCGCATGGGG CTGGACGGCT GCGTGGAAGA CTTGCGCAGC 
CGCCTGCAGC GCGGCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683866.1
CDS	89..1369
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTPPPSLAGAPWGAVQSAVPLSVAGGRVGVFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP

Target ORF information:

RefSeq Version	NM_148965.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148965.1

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGCCACCCC CGTCCCTTGC AGGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG 
TCTGTGGCTG GAGGCAGAGT AGGTGTGTTC TGGGTCCAGG TGCTCCTGGC TGGCCTTGTG 
GTCCCCCTCC TGCTTGGGGC CACCCTGACC TACACATACC GCCACTGCTG GCCTCACAAG 
CCCCTGGTTA CTGCAGATGA AGCTGGGATG GAGGCTCTGA CCCCACCACC GGCCACCCAT 
CTGTCACCCT TGGACAGCGC CCACACCCTT CTAGCACCTC CTGACAGCAG TGAGAAGATC 
TGCACCGTCC AGTTGGTGGG TAACAGCTGG ACCCCTGGCT ACCCCGAGAC CCAGGAGGCG 
CTCTGCCCGC AGGTGACATG GTCCTGGGAC CAGTTGCCCA GCAGAGCTCT TGGCCCCGCT 
GCTGCGCCCA CACTCTCGCC AGAGTCCCCA GCCGGCTCGC CAGCCATGAT GCTGCAGCCG 
GGCCCGCAGC TCTACGACGT GATGGACGCG GTCCCAGCGC GGCGCTGGAA GGAGTTCGTG 
CGCACGCTGG GGCTGCGCGA GGCAGAGATC GAAGCCGTGG AGGTGGAGAT CGGCCGCTTC 
CGAGACCAGC AGTACGAGAT GCTCAAGCGC TGGCGCCAGC AGCAGCCCGC GGGCCTCGGA 
GCCGTTTACG CGGCCCTGGA GCGCATGGGG CTGGACGGCT GCGTGGAAGA CTTGCGCAGC 
CGCCTGCAGC GCGGCCCGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF25 ( NM_148967.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_683868.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu26611
Clone ID Related Accession (Same CDS sequence)	NM_148967.1
Accession Version	NM_148967.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 4 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358309.1, U94509.1 and BM666370.1. Transcript Variant: This variant (4) lacks three coding segments, two of which result in a frameshift, when compared to variant 1. The resulting isoform (4) lacks an internal region, and contains a distinct and shorter internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U94509.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01820687, SAMN01820701 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG CCTCCCAGGT GGCGCTGGAG 
AACTGTTCAG CAGTGGCCGA CACCCGCTGT GGCTGTAAGC CAGGCTGGTT TGTGGAGTGC 
CAGGTCAGCC AATGTGTCAG CAGTTCACCC TTCTACTGCC AACCATGCCT AGACTGCGGG 
GCCCTGCACC GCCACACACG GCTACTCTGT TCCCGCAGAG ATACTGACTG TGGGACCTGC 
CTGCCTGGCT TCTATGAACA TGGCGATGGC TGCGTGTCCT GCCCCACGAG CACCCTGGGG 
AGCTGTCCAG AGCGCTGTGC CGCTGTCTGT GGCTGGAGGC AGATGTTCTG GGTCCAGGTG 
CTCCTGGCTG GCCTTGTGGT CCCCCTCCTG CTTGGGGCCA CCCTGACCTA CACATACCGC 
CACTGCTGGC CTCACAAGCC CCTGGTTACT GCAGATGAAG CTGGGATGGA GGCTCTGACC 
CCACCACCGG CCACCCATCT GTCACCCTTG GACAGCGCCC ACACCCTTCT AGCACCTCCT 
GACAGCAGTG AGAAGATCTG CACCGTCCAG TTGGTGGGTA ACAGCTGGAC CCCTGGCTAC 
CCCGAGACCC AGGAGGCGCT CTGCCCGCAG GTGACATGGT CCTGGGACCA GTTGCCCAGC 
AGAGCTCTTG GCCCCGCTGC TGCGCCCACA CTCTCGCCAG AGTCCCCAGC CGGCTCGCCA 
GCCATGATGC TGCAGCCGGG CCCGCAGCTC TACGACGTGA TGGACGCGGT CCCAGCGCGG 
CGCTGGAAGG AGTTCGTGCG CACGCTGGGG CTGCGCGAGG CAGAGATCGA AGCCGTGGAG 
GTGGAGATCG GCCGCTTCCG AGACCAGCAG TACGAGATGC TCAAGCGCTG GCGCCAGCAG 
CAGCCCGCGG GCCTCGGAGC CGTTTACGCG GCCCTGGAGC GCATGGGGCT GGACGGCTGC 
GTGGAAGACT TGCGCAGCCG CCTGCAGCGC GGCCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683868.1
CDS	89..1207
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQMFWVQVLLAGLVVPLLLGATLTYTYRHCWPHKPLVTADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP

Target ORF information:

RefSeq Version	NM_148967.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148967.1

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG CCTCCCAGGT GGCGCTGGAG 
AACTGTTCAG CAGTGGCCGA CACCCGCTGT GGCTGTAAGC CAGGCTGGTT TGTGGAGTGC 
CAGGTCAGCC AATGTGTCAG CAGTTCACCC TTCTACTGCC AACCATGCCT AGACTGCGGG 
GCCCTGCACC GCCACACACG GCTACTCTGT TCCCGCAGAG ATACTGACTG TGGGACCTGC 
CTGCCTGGCT TCTATGAACA TGGCGATGGC TGCGTGTCCT GCCCCACGAG CACCCTGGGG 
AGCTGTCCAG AGCGCTGTGC CGCTGTCTGT GGCTGGAGGC AGATGTTCTG GGTCCAGGTG 
CTCCTGGCTG GCCTTGTGGT CCCCCTCCTG CTTGGGGCCA CCCTGACCTA CACATACCGC 
CACTGCTGGC CTCACAAGCC CCTGGTTACT GCAGATGAAG CTGGGATGGA GGCTCTGACC 
CCACCACCGG CCACCCATCT GTCACCCTTG GACAGCGCCC ACACCCTTCT AGCACCTCCT 
GACAGCAGTG AGAAGATCTG CACCGTCCAG TTGGTGGGTA ACAGCTGGAC CCCTGGCTAC 
CCCGAGACCC AGGAGGCGCT CTGCCCGCAG GTGACATGGT CCTGGGACCA GTTGCCCAGC 
AGAGCTCTTG GCCCCGCTGC TGCGCCCACA CTCTCGCCAG AGTCCCCAGC CGGCTCGCCA 
GCCATGATGC TGCAGCCGGG CCCGCAGCTC TACGACGTGA TGGACGCGGT CCCAGCGCGG 
CGCTGGAAGG AGTTCGTGCG CACGCTGGGG CTGCGCGAGG CAGAGATCGA AGCCGTGGAG 
GTGGAGATCG GCCGCTTCCG AGACCAGCAG TACGAGATGC TCAAGCGCTG GCGCCAGCAG 
CAGCCCGCGG GCCTCGGAGC CGTTTACGCG GCCCTGGAGC GCATGGGGCT GGACGGCTGC 
GTGGAAGACT TGCGCAGCCG CCTGCAGCGC GGCCCGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF25 ( NM_148966.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_683867.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu27008
Clone ID Related Accession (Same CDS sequence)	NM_148966.1
Accession Version	NM_148966.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1143bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358309.1, BC143886.1 and BM666370.1. Transcript Variant: This variant (3) lacks two coding segments, both of which result in a frameshift, when compared to variant 1. The resulting isoform (3) contains a distinct and shorter internal segment, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC143886.1, U94510.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG TCTGTGGCTG GAGGCAGAAT 
GAAGCTGGGA TGGAGGCTCT GACCCCACCA CCGGCCACCC ATCTGTCACC CTTGGACAGC 
GCCCACACCC TTCTAGCACC TCCTGACAGC AGTGAGAAGA TCTGCACCGT CCAGTTGGTG 
GGTAACAGCT GGACCCCTGG CTACCCCGAG ACCCAGGAGG CGCTCTGCCC GCAGGTGACA 
TGGTCCTGGG ACCAGTTGCC CAGCAGAGCT CTTGGCCCCG CTGCTGCGCC CACACTCTCG 
CCAGAGTCCC CAGCCGGCTC GCCAGCCATG ATGCTGCAGC CGGGCCCGCA GCTCTACGAC 
GTGATGGACG CGGTCCCAGC GCGGCGCTGG AAGGAGTTCG TGCGCACGCT GGGGCTGCGC 
GAGGCAGAGA TCGAAGCCGT GGAGGTGGAG ATCGGCCGCT TCCGAGACCA GCAGTACGAG 
ATGCTCAAGC GCTGGCGCCA GCAGCAGCCC GCGGGCCTCG GAGCCGTTTA CGCGGCCCTG 
GAGCGCATGG GGCTGGACGG CTGCGTGGAA GACTTGCGCA GCCGCCTGCA GCGCGGCCCG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683867.1
CDS	89..1231
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPAGHYLKAPCTEPCGNSTCLVCPQDTFLAWENHHNSECARCQACDEQASQVALENCSAVADTRCGCKPGWFVECQVSQCVSSSPFYCQPCLDCGALHRHTRLLCSRRDTDCGTCLPGFYEHGDGCVSCPTSTLGSCPERCAAVCGWRQNEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP

Target ORF information:

RefSeq Version	NM_148966.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148966.1

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG GGCACTACCT GAAGGCCCCT 
TGCACGGAGC CCTGCGGCAA CTCCACCTGC CTTGTGTGTC CCCAAGACAC CTTCTTGGCC 
TGGGAGAACC ACCATAATTC TGAATGTGCC CGCTGCCAGG CCTGTGATGA GCAGGCCTCC 
CAGGTGGCGC TGGAGAACTG TTCAGCAGTG GCCGACACCC GCTGTGGCTG TAAGCCAGGC 
TGGTTTGTGG AGTGCCAGGT CAGCCAATGT GTCAGCAGTT CACCCTTCTA CTGCCAACCA 
TGCCTAGACT GCGGGGCCCT GCACCGCCAC ACACGGCTAC TCTGTTCCCG CAGAGATACT 
GACTGTGGGA CCTGCCTGCC TGGCTTCTAT GAACATGGCG ATGGCTGCGT GTCCTGCCCC 
ACGAGCACCC TGGGGAGCTG TCCAGAGCGC TGTGCCGCTG TCTGTGGCTG GAGGCAGAAT 
GAAGCTGGGA TGGAGGCTCT GACCCCACCA CCGGCCACCC ATCTGTCACC CTTGGACAGC 
GCCCACACCC TTCTAGCACC TCCTGACAGC AGTGAGAAGA TCTGCACCGT CCAGTTGGTG 
GGTAACAGCT GGACCCCTGG CTACCCCGAG ACCCAGGAGG CGCTCTGCCC GCAGGTGACA 
TGGTCCTGGG ACCAGTTGCC CAGCAGAGCT CTTGGCCCCG CTGCTGCGCC CACACTCTCG 
CCAGAGTCCC CAGCCGGCTC GCCAGCCATG ATGCTGCAGC CGGGCCCGCA GCTCTACGAC 
GTGATGGACG CGGTCCCAGC GCGGCGCTGG AAGGAGTTCG TGCGCACGCT GGGGCTGCGC 
GAGGCAGAGA TCGAAGCCGT GGAGGTGGAG ATCGGCCGCT TCCGAGACCA GCAGTACGAG 
ATGCTCAAGC GCTGGCGCCA GCAGCAGCCC GCGGGCCTCG GAGCCGTTTA CGCGGCCCTG 
GAGCGCATGG GGCTGGACGG CTGCGTGGAA GACTTGCGCA GCCGCCTGCA GCGCGGCCCG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TNFRSF25 ( NM_148970.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_683871.1 Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu27342
Clone ID Related Accession (Same CDS sequence)	NM_148970.1
Accession Version	NM_148970.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 705bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Homo sapiens(human)
Product	tumor necrosis factor receptor superfamily member 25 isoform 7 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358309.1, U94508.1 and BM666370.1. Transcript Variant: This variant (7) lacks an in-frame coding segment compared to variant 1. The resulting isoform (7) lacks an internal region, as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: U94508.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG ATGAAGCTGG GATGGAGGCT 
CTGACCCCAC CACCGGCCAC CCATCTGTCA CCCTTGGACA GCGCCCACAC CCTTCTAGCA 
CCTCCTGACA GCAGTGAGAA GATCTGCACC GTCCAGTTGG TGGGTAACAG CTGGACCCCT 
GGCTACCCCG AGACCCAGGA GGCGCTCTGC CCGCAGGTGA CATGGTCCTG GGACCAGTTG 
CCCAGCAGAG CTCTTGGCCC CGCTGCTGCG CCCACACTCT CGCCAGAGTC CCCAGCCGGC 
TCGCCAGCCA TGATGCTGCA GCCGGGCCCG CAGCTCTACG ACGTGATGGA CGCGGTCCCA 
GCGCGGCGCT GGAAGGAGTT CGTGCGCACG CTGGGGCTGC GCGAGGCAGA GATCGAAGCC 
GTGGAGGTGG AGATCGGCCG CTTCCGAGAC CAGCAGTACG AGATGCTCAA GCGCTGGCGC 
CAGCAGCAGC CCGCGGGCCT CGGAGCCGTT TACGCGGCCC TGGAGCGCAT GGGGCTGGAC 
GGCTGCGTGG AAGACTTGCG CAGCCGCCTG CAGCGCGGCC CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_683871.1
CDS	89..793
Translation	MEQRPRGCAAVAAALLLVLLGARAQGGTRSPRCDCAGDFHKKIGLFCCRGCPADEAGMEALTPPPATHLSPLDSAHTLLAPPDSSEKICTVQLVGNSWTPGYPETQEALCPQVTWSWDQLPSRALGPAAAPTLSPESPAGSPAMMLQPGPQLYDVMDAVPARRWKEFVRTLGLREAEIEAVEVEIGRFRDQQYEMLKRWRQQQPAGLGAVYAALERMGLDGCVEDLRSRLQRGP

Target ORF information:

RefSeq Version	NM_148970.1
Organism	Homo sapiens(human)
Definition	Homo sapiens TNF receptor superfamily member 25 (TNFRSF25), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_148970.1

ORF Insert Sequence:

ATGGAGCAGC GGCCGCGGGG CTGCGCGGCG GTGGCGGCGG CGCTCCTCCT GGTGCTGCTG 
GGGGCCCGGG CCCAGGGCGG CACTCGTAGC CCCAGGTGTG ACTGTGCCGG TGACTTCCAC 
AAGAAGATTG GTCTGTTTTG TTGCAGAGGC TGCCCAGCGG ATGAAGCTGG GATGGAGGCT 
CTGACCCCAC CACCGGCCAC CCATCTGTCA CCCTTGGACA GCGCCCACAC CCTTCTAGCA 
CCTCCTGACA GCAGTGAGAA GATCTGCACC GTCCAGTTGG TGGGTAACAG CTGGACCCCT 
GGCTACCCCG AGACCCAGGA GGCGCTCTGC CCGCAGGTGA CATGGTCCTG GGACCAGTTG 
CCCAGCAGAG CTCTTGGCCC CGCTGCTGCG CCCACACTCT CGCCAGAGTC CCCAGCCGGC 
TCGCCAGCCA TGATGCTGCA GCCGGGCCCG CAGCTCTACG ACGTGATGGA CGCGGTCCCA 
GCGCGGCGCT GGAAGGAGTT CGTGCGCACG CTGGGGCTGC GCGAGGCAGA GATCGAAGCC 
GTGGAGGTGG AGATCGGCCG CTTCCGAGAC CAGCAGTACG AGATGCTCAA GCGCTGGCGC 
CAGCAGCAGC CCGCGGGCCT CGGAGCCGTT TACGCGGCCC TGGAGCGCAT GGGGCTGGAC 
GGCTGCGTGG AAGACTTGCG CAGCCGCCTG CAGCGCGGCC CGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

DNA methylation polymerase chain reaction (PCR) array of apoptosis-related genes in pleomorphic adenomas of the salivary glands.
Oral surgery, oral medicine, oral pathology and oral radiology124(6)554-560(2017 Dec)
Pereira NB,do Carmo ACM,Campos K,Costa SFDS,Diniz MG,Gomez RS,Gomes CC

CCL3 and MMP-9 are induced by TL1A during death receptor 3 (TNFRSF25)-dependent osteoclast function and systemic bone loss.
Bone9794-104(2017 04)
Collins FL,Williams JO,Bloom AC,Singh RK,Jordan L,Stone MD,McCabe LR,Wang ECY,Williams AS

Death receptor 3 signaling enhances proliferation of human regulatory T cells.
FEBS letters591(8)1187-1195(2017 04)
Bittner S,Knoll G,Ehrenschwender M

Crohn's disease-associated mucosal factors regulate the expression of TNF-like cytokine 1A and its receptors in primary subepithelial intestinal myofibroblasts and intestinal epithelial cells.
Translational research : the journal of laboratory and clinical medicine180118-130.e2(2017 Feb)
Bamias G,Filidou E,Goukos D,Valatas V,Arvanitidis K,Panagopoulou M,Kouklakis G,Daikos GL,Ladas SD,Kolios G

DR3 regulation of apoptosis of naive T-lymphocytes in children with acute infectious mononucleosis.
Acta microbiologica et immunologica Hungarica63(3)339-357(2016 Sep)
Filatova EN,Anisenkova EV,Presnyakova NB,Utkin OV

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TNFRSF25 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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