Gene Symbol | DOCK7 |
Entrez Gene ID | 85440 |
Full Name | dedicator of cytokinesis 7 |
Synonyms | EIEE23,ZIR2 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a guanine nucleotide exchange factor (GEF) that plays a role in axon formation and neuronal polarization. The encoded protein displays GEF activity toward RAC1 and RAC3 Rho small GTPases but not toward CDC42. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]. |
Disorder MIM: | |
Disorder Html: | Epileptic encephalopathy, early infantile, 23, 615859 (3) |