KRTAP4-2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KRTAP4-2
Entrez Gene ID	85291
Full Name	keratin associated protein 4-2
Synonyms	KAP4.2,KRTAP4.2
General protein information	Preferred Names keratin associated protein 4-2 Names keratin-associated protein 4-2 keratin-associated protein 4.2 ultrahigh sulfur keratin-associated protein 4.2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17q21.2
Summary	This protein is a member of the keratin-associated protein (KAP) family. The KAP proteins form a matrix of keratin intermediate filaments which contribute to the structure of hair fibers. KAP family members appear to have unique, family-specific amino- and carboxyl-terminal regions and are subdivided into three multi-gene families according to amino acid composition: the high sulfur, the ultrahigh sulfur, and the high tyrosine/glycine KAPs. This protein is a member of the ultrahigh sulfur KAP family and the gene is localized to a cluster of KAPs at 17q12-q21. [provided by RefSeq, Jul 2008].

mRNA and Protein(s)

mRNA	Protein	Name
NM_033062.3	NP_149051.1	keratin-associated protein 4-2
NM_033062.4	NP_149051.2	keratin-associated protein 4-2

Pathways from BioSystems

Homologies

Homo sapiens (human)	KRTAP4-2	NP_149051.1
Pan troglodytes (chimpanzee)	LOC101059050	XP_003953070.1
	LOC704430	XP_001104195.1

Gene Ontology
Bibliography

Related articles in PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Yang X, Coulombe-Huntington J, Kang S, Sheynkman GM, Hao T, Richardson A, Sun S, Yang F, Shen YA, Murray RR, Spirohn K, Begg BE, Duran-Frigola M, MacWilliams A, Pevzner SJ, Zhong Q, Trigg SA, Tam S, Ghamsari L, Sahni N, Yi S, Rodriguez MD, Balcha D, Tan G, Costanzo M, Andrews B, Boone C, Zhou XJ, Salehi-Ashtiani K, Charloteaux B, Chen AA, Calderwood MA, Aloy P, Roth FP, Hill DE, Iakoucheva LM, Xia Y, Vidal M
Cell164(4)805-17(2016 Feb)

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
Rogers MA, Langbein L, Winter H, Ehmann C, Praetzel S, Korn B, Schweizer J
The Journal of biological chemistry276(22)19440-51(2001 Jun)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KRTAP4-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KRTAP4-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu00375	NM_033062.3 Latest version!	Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu108598	NM_033062.4 Latest version!	Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KRTAP4-2 ( NM_033062.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_149051.1 Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.

Price & Availability↑

CloneID	OHu00375
Clone ID Related Accession (Same CDS sequence)	NM_033062.3
Accession Version	NM_033062.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-23
Organism	Homo sapiens(human)
Product	keratin-associated protein 4-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC006070.1 and AJ406934.1. On May 21, 2011 this sequence version replaced NM_033062.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript represented the more frequently occurring allele. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: AJ406934.1 [ECO:0000345] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT AGAGAACTGC 
TGCCGTCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCGCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCAGCCCCA GCTGCTGCCA GACCACTTGC TGCAGGACCA CCTGCTGCCG TCCCAGCTGC 
TGTGTGTCCA GCTGCTTCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGTGGCCA GACCACCTGC TGCAGGACCA CCTGCTACCG CCCCAGCTGC 
TGTGTGTCCA CCTGCTGCCG CCCAACCTGC TCTAGTGGCT CTTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149051.1
CDS	45..455
Translation	MVNSCCGSVCSDQGCGLENCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCSPSCCQTTCCRTTCCRPSCCVSSCFRPQCCQSVCCQPTCCRPSCGQTTCCRTTCYRPSCCVSTCCRPTCSSGSCC

Target ORF information:

RefSeq Version	NM_033062.3
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033062.3

ORF Insert Sequence:

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT AGAGAACTGC 
TGCCGTCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCGCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCAGCCCCA GCTGCTGCCA GACCACTTGC TGCAGGACCA CCTGCTGCCG TCCCAGCTGC 
TGTGTGTCCA GCTGCTTCAG ACCCCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGTGGCCA GACCACCTGC TGCAGGACCA CCTGCTACCG CCCCAGCTGC 
TGTGTGTCCA CCTGCTGCCG CCCAACCTGC TCTAGTGGCT CTTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KRTAP4-2 ( NM_033062.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_149051.2 Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.

Price & Availability↑

CloneID	OHu108598
Clone ID Related Accession (Same CDS sequence)	NM_033062.4
Accession Version	NM_033062.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 411bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	keratin-associated protein 4-2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff in collaboration with Michael Rogers. The reference sequence was derived from AC006070.1. On May 17, 2019 this sequence version replaced NM_033062.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript represented the more frequently occurring allele. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript is intronless :: AJ406934.1, BC127252.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000377726.3/ ENSP00000366955.2 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT AGAGAACTGC 
TGCCGTCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCGCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCAGCCCCA GCTGCTGCCA GACCACTTGC TGCAGGACCA CCTGCTGCCG TCCCAGCTGC 
TGTGTGTCCA GCTGCTTCAG ACCCCAGTGC TGCCAGTCTG TGTACTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGTGGCCA GACCACCTGC TGCAGGACCA CCTGCTACCG CCCCAGCTGC 
TGTGTGTCCA CCTGCTGCCG CCCAACCTGC TCTAGTGGCT CTTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_149051.2
CDS	58..468
Translation	MVNSCCGSVCSDQGCGLENCCRPSCCQTTCCRTTCCRPSCCVSSCCRPQCCQSVCCQPTCCSPSCCQTTCCRTTCCRPSCCVSSCFRPQCCQSVYCQPTCCRPSCGQTTCCRTTCYRPSCCVSTCCRPTCSSGSCC

Target ORF information:

RefSeq Version	NM_033062.4
Organism	Homo sapiens(human)
Definition	Homo sapiens keratin associated protein 4-2 (KRTAP4-2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_033062.4

ORF Insert Sequence:

ATGGTCAACT CCTGTTGTGG CTCTGTGTGC TCTGACCAGG GCTGTGGCCT AGAGAACTGC 
TGCCGTCCCA GCTGCTGCCA GACCACCTGC TGCAGGACCA CCTGCTGCCG CCCCAGCTGC 
TGTGTGTCCA GCTGCTGCAG ACCGCAGTGC TGCCAGTCTG TGTGCTGCCA GCCCACCTGC 
TGCAGCCCCA GCTGCTGCCA GACCACTTGC TGCAGGACCA CCTGCTGCCG TCCCAGCTGC 
TGTGTGTCCA GCTGCTTCAG ACCCCAGTGC TGCCAGTCTG TGTACTGCCA GCCCACCTGC 
TGCCGCCCCA GCTGTGGCCA GACCACCTGC TGCAGGACCA CCTGCTACCG CCCCAGCTGC 
TGTGTGTCCA CCTGCTGCCG CCCAACCTGC TCTAGTGGCT CTTGCTGCTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Widespread Expansion of Protein Interaction Capabilities by Alternative Splicing.
Cell164(4)805-17(2016 Feb)
Yang X,Coulombe-Huntington J,Kang S,Sheynkman GM,Hao T,Richardson A,Sun S,Yang F,Shen YA,Murray RR,Spirohn K,Begg BE,Duran-Frigola M,MacWilliams A,Pevzner SJ,Zhong Q,Trigg SA,Tam S,Ghamsari L,Sahni N,Yi S,Rodriguez MD,Balcha D,Tan G,Costanzo M,Andrews B,Boone C,Zhou XJ,Salehi-Ashtiani K,Charloteaux B,Chen AA,Calderwood MA,Aloy P,Roth FP,Hill DE,Iakoucheva LM,Xia Y,Vidal M

Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.
The Journal of biological chemistry276(22)19440-51(2001 Jun)
Rogers MA,Langbein L,Winter H,Ehmann C,Praetzel S,Korn B,Schweizer J

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KRTAP4-2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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