HIRIP3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HIRIP3
Entrez Gene ID	8479
Full Name	HIRA interacting protein 3
General protein information	Preferred Names HIRA interacting protein 3 Names HIRA-interacting protein 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	The HIRA protein shares sequence similarity with Hir1p and Hir2p, the two corepressors of histone gene transcription characterized in the yeast, Saccharomyces cerevisiae. The structural features of the HIRA protein suggest that it may function as part of a multiprotein complex. Several cDNAs encoding HIRA-interacting proteins, or HIRIPs, have been identified. In vitro, the protein encoded by this gene binds HIRA, as well as H2B and H3 core histones, indicating that a complex containing HIRA-HIRIP3 could function in some aspects of chromatin and histone metabolism. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.[provided by RefSeq, Aug 2011].
Disorder MIM:	603365

mRNA and Protein(s)

mRNA	Protein	Name
NM_001197323.1	NP_001184252.1	HIRA-interacting protein 3 isoform 2
NM_003609.4	NP_003600.2	HIRA-interacting protein 3 isoform 1
NM_003609.5	NP_003600.2	HIRA-interacting protein 3 isoform 1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Hirip3	NP_001020896.1
Canis lupus familiaris (dog)	HIRIP3	XP_005621403.1
Bos taurus (cattle)	HIRIP3	NP_001179225.1
Homo sapiens (human)	HIRIP3	NP_003600.2
Pan troglodytes (chimpanzee)	HIRIP3	XP_001146729.1
	HIRIP3	XP_001107024.1
Mus musculus (house mouse)	Hirip3	NP_766334.1

Gene Ontology
Bibliography

Related articles in PubMed

Biological insights from 108 schizophrenia-associated genetic loci.

Nature511(7510)421-7(2014 Jul)

Association and mutation analyses of 16p11.2 autism candidate genes.
Kumar RA, Marshall CR, Badner JA, Babatz TD, Mukamel Z, Aldinger KA, Sudi J, Brune CW, Goh G, Karamohamed S, Sutcliffe JS, Cook EH, Geschwind DH, Dobyns WB, Scherer SW, Christian SL
PloS one4(2)e4582(2009)

HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2.
Assrir N, Filhol O, Galisson F, Lipinski M
Biological chemistry388(4)391-8(2007 Apr)

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Beausoleil SA, Vill?n J, Gerber SA, Rush J, Gygi SP
Nature biotechnology24(10)1285-92(2006 Oct)

A germline-specific class of small RNAs binds mammalian Piwi proteins.
Girard A, Sachidanandam R, Hannon GJ, Carmell MA
Nature442(7099)199-202(2006 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association. (HuGE Navigator)
Title: Association and mutation analyses of 16p11.2 autism candidate genes.

HIRIP3 can be phosphorylated in vitro by a recombinant form of the serine-threonine kinase CK2. Moreover, HIRIP3 protein was found to co-purify with a CK2 activity.
Title: HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2.

The following HIRIP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HIRIP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu55880	NM_003609.5 Latest version!	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu55874	NM_001197323.1 Latest version!	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$69.30 $99.00
View Old Accession Versions >>
OHu55880	NM_003609.4	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HIRIP3 ( NM_003609.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003600.2 Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55880
Clone ID Related Accession (Same CDS sequence)	NM_003609.4 , NM_003609.5
Accession Version	NM_003609.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	HIRA-interacting protein 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA716463.1, BC000588.2, Z25386.1, BU629222.1, BX101682.1 and BM673568.1. On Aug 24, 2011 this sequence version replaced NM_003609.3. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1803616.8830.1, SRR1803613.263800.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GAGTCCGGCT CTGAAGCCTC CAGCCCAGAC TACTTTGGAC CCCCAGCAAA GAATGGGGTG 
GCAGCAGAAG TCAGCCCAGC CAAAGAGGAG AATCCAAGGC GAGCCTCAAA GGCAGTTGAG 
GAGAGCAGTG ATGAGGAACG GCAGAGGGAC CTGCCCGCAC AGAGGGGAGA GGAGAGCAGT 
GAGGAGGAGG AAAAGGGGTA CAAGGGGAAG ACTAGGAAGA AACCTGTGGT AAAGAAGCAG 
GCACCAGGCA AGGCCTCAGT CAGTAGGAAG CAGGCCAGGG AAGAAAGTGA GGAGAGCGAG 
GCAGAACCCG TTCAGAGGAC AGCAAAGAAG GTGGAGGGAA ATAAAGGAAC TAAAAGCCTG 
AAGGAAAGTG AACAGGAGAG TGAAGAGGAG ATCCTAGCCC AGAAGAAAGA GCAGAGAGAG 
GAGGAAGTGG AGGAGGAAGA GAAAGAAGAG GATGAGGAAA AGGGGGATTG GAAACCCAGA 
ACCAGGAGCA ATGGCCGGAG AAAGTCAGCT AGGGAGGAGA GGAGCTGTAA GCAGAAAAGC 
CAGGCAAAGA GGCTCTTGGG AGACTCAGAC AGCGAGGAAG AGCAGAAAGA GGCAGCCAGC 
AGTGGGGATG ACAGTGGGAG AGATAGAGAA CCCCCAGTGC AGAGGAAGAG TGAGGACAGG 
ACCCAGCTTA AGGGTGGGAA GAGGTTGAGT GGAAGCAGCG AGGACGAGGA AGACAGTGGG 
AAGGGGGAAC CCACAGCTAA AGGCTCTAGA AAGATGGCCA GACTGGGCAG CACCAGTGGT 
GAGGAAAGTG ACTTGGAGAG GGAGGTAAGT GACAGCGAGG CAGGGGGAGG CCCCCAGGGG 
GAGAGGAAGA ACCGCTCTTC CAAGAAGAGC TCCAGGAAAG GCAGGACACG AAGCTCCTCT 
TCCTCCTCAG ATGGAAGTCC AGAGGCCAAA GGAGGGAAGG CTGGCTCAGG TCGCCGTGGA 
GAGGACCACC CGGCTGTGAT GAGGCTGAAG CGCTACATTC GGGCCTGTGG TGCCCATCGA 
AACTACAAGA AGCTGTTGGG CTCCTGTTGC TCACACAAGG AGCGCCTGAG TATCCTCCGG 
GCAGAACTGG AAGCGCTAGG CATGAAGGGT ACCCCTTCCC TAGGGAAGTG TCGGGCCCTG 
AAGGAGCAGA GGGAGGAGGC AGCTGAGGTG GCCTCCTTGG ATGTTGCGAA CATCATCAGT 
GGCTCGGGCC GGCCACGCAG ACGTACAGCC TGGAACCCTT TAGGAGAAGC AGCACCCCCA 
GGGGAGCTGT ACCGACGGAC CCTGGACTCA GATGAAGAGC GGCCCCGTCC CGCACCCCCA 
GACTGGTCAC ATATGCGTGG CATCATCAGC AGTGATGGCG AGAGTAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003600.2
CDS	492..2162
Translation	MAREKEMQEFTRSFFRGRPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGEDHPAVMRLKRYIRACGAHRNYKKLLGSCCSHKERLSILRAELEALGMKGTPSLGKCRALKEQREEAAEVASLDVANIISGSGRPRRRTAWNPLGEAAPPGELYRRTLDSDEERPRPAPPDWSHMRGIISSDGESN

Target ORF information:

RefSeq Version	NM_003609.4
Organism	Homo sapiens(human)
Definition	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003609.4

ORF Insert Sequence:

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GAGTCCGGCT CTGAAGCCTC CAGCCCAGAC TACTTTGGAC CCCCAGCAAA GAATGGGGTG 
GCAGCAGAAG TCAGCCCAGC CAAAGAGGAG AATCCAAGGC GAGCCTCAAA GGCAGTTGAG 
GAGAGCAGTG ATGAGGAACG GCAGAGGGAC CTGCCCGCAC AGAGGGGAGA GGAGAGCAGT 
GAGGAGGAGG AAAAGGGGTA CAAGGGGAAG ACTAGGAAGA AACCTGTGGT AAAGAAGCAG 
GCACCAGGCA AGGCCTCAGT CAGTAGGAAG CAGGCCAGGG AAGAAAGTGA GGAGAGCGAG 
GCAGAACCCG TTCAGAGGAC AGCAAAGAAG GTGGAGGGAA ATAAAGGAAC TAAAAGCCTG 
AAGGAAAGTG AACAGGAGAG TGAAGAGGAG ATCCTAGCCC AGAAGAAAGA GCAGAGAGAG 
GAGGAAGTGG AGGAGGAAGA GAAAGAAGAG GATGAGGAAA AGGGGGATTG GAAACCCAGA 
ACCAGGAGCA ATGGCCGGAG AAAGTCAGCT AGGGAGGAGA GGAGCTGTAA GCAGAAAAGC 
CAGGCAAAGA GGCTCTTGGG AGACTCAGAC AGCGAGGAAG AGCAGAAAGA GGCAGCCAGC 
AGTGGGGATG ACAGTGGGAG AGATAGAGAA CCCCCAGTGC AGAGGAAGAG TGAGGACAGG 
ACCCAGCTTA AGGGTGGGAA GAGGTTGAGT GGAAGCAGCG AGGACGAGGA AGACAGTGGG 
AAGGGGGAAC CCACAGCTAA AGGCTCTAGA AAGATGGCCA GACTGGGCAG CACCAGTGGT 
GAGGAAAGTG ACTTGGAGAG GGAGGTAAGT GACAGCGAGG CAGGGGGAGG CCCCCAGGGG 
GAGAGGAAGA ACCGCTCTTC CAAGAAGAGC TCCAGGAAAG GCAGGACACG AAGCTCCTCT 
TCCTCCTCAG ATGGAAGTCC AGAGGCCAAA GGAGGGAAGG CTGGCTCAGG TCGCCGTGGA 
GAGGACCACC CGGCTGTGAT GAGGCTGAAG CGCTACATTC GGGCCTGTGG TGCCCATCGA 
AACTACAAGA AGCTGTTGGG CTCCTGTTGC TCACACAAGG AGCGCCTGAG TATCCTCCGG 
GCAGAACTGG AAGCGCTAGG CATGAAGGGT ACCCCTTCCC TAGGGAAGTG TCGGGCCCTG 
AAGGAGCAGA GGGAGGAGGC AGCTGAGGTG GCCTCCTTGG ATGTTGCGAA CATCATCAGT 
GGCTCGGGCC GGCCACGCAG ACGTACAGCC TGGAACCCTT TAGGAGAAGC AGCACCCCCA 
GGGGAGCTGT ACCGACGGAC CCTGGACTCA GATGAAGAGC GGCCCCGTCC CGCACCCCCA 
GACTGGTCAC ATATGCGTGG CATCATCAGC AGTGATGGCG AGAGTAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HIRIP3 ( NM_003609.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003600.2 Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu55880
Clone ID Related Accession (Same CDS sequence)	NM_003609.4 , NM_003609.5
Accession Version	NM_003609.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1671bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	HIRA-interacting protein 3 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC000588.2, Z25386.1, BU629222.1 and BX101682.1. On May 17, 2019 this sequence version replaced NM_003609.4. Transcript Variant: This variant (1) encodes the longer isoform (1). ##Evidence-Data-START## Transcript exon combination :: SRR1660805.104665.1, SRR3476690.866475.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2145245 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000279392.8/ ENSP00000279392.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GAGTCCGGCT CTGAAGCCTC CAGCCCAGAC TACTTTGGAC CCCCAGCAAA GAATGGGGTG 
GCAGCAGAAG TCAGCCCAGC CAAAGAGGAG AATCCAAGGC GAGCCTCAAA GGCAGTTGAG 
GAGAGCAGTG ATGAGGAACG GCAGAGGGAC CTGCCCGCAC AGAGGGGAGA GGAGAGCAGT 
GAGGAGGAGG AAAAGGGGTA CAAGGGGAAG ACTAGGAAGA AACCTGTGGT AAAGAAGCAG 
GCACCAGGCA AGGCCTCAGT CAGTAGGAAG CAGGCCAGGG AAGAAAGTGA GGAGAGCGAG 
GCAGAACCCG TTCAGAGGAC AGCAAAGAAG GTGGAGGGAA ATAAAGGAAC TAAAAGCCTG 
AAGGAAAGTG AACAGGAGAG TGAAGAGGAG ATCCTAGCCC AGAAGAAAGA GCAGAGAGAG 
GAGGAAGTGG AGGAGGAAGA GAAAGAAGAG GATGAGGAAA AGGGGGATTG GAAACCCAGA 
ACCAGGAGCA ATGGCCGGAG AAAGTCAGCT AGGGAGGAGA GGAGCTGTAA GCAGAAAAGC 
CAGGCAAAGA GGCTCTTGGG AGACTCAGAC AGCGAGGAAG AGCAGAAAGA GGCAGCCAGC 
AGTGGGGATG ACAGTGGGAG AGATAGAGAA CCCCCAGTGC AGAGGAAGAG TGAGGACAGG 
ACCCAGCTTA AGGGTGGGAA GAGGTTGAGT GGAAGCAGCG AGGACGAGGA AGACAGTGGG 
AAGGGGGAAC CCACAGCTAA AGGCTCTAGA AAGATGGCCA GACTGGGCAG CACCAGTGGT 
GAGGAAAGTG ACTTGGAGAG GGAGGTAAGT GACAGCGAGG CAGGGGGAGG CCCCCAGGGG 
GAGAGGAAGA ACCGCTCTTC CAAGAAGAGC TCCAGGAAAG GCAGGACACG AAGCTCCTCT 
TCCTCCTCAG ATGGAAGTCC AGAGGCCAAA GGAGGGAAGG CTGGCTCAGG TCGCCGTGGA 
GAGGACCACC CGGCTGTGAT GAGGCTGAAG CGCTACATTC GGGCCTGTGG TGCCCATCGA 
AACTACAAGA AGCTGTTGGG CTCCTGTTGC TCACACAAGG AGCGCCTGAG TATCCTCCGG 
GCAGAACTGG AAGCGCTAGG CATGAAGGGT ACCCCTTCCC TAGGGAAGTG TCGGGCCCTG 
AAGGAGCAGA GGGAGGAGGC AGCTGAGGTG GCCTCCTTGG ATGTTGCGAA CATCATCAGT 
GGCTCGGGCC GGCCACGCAG ACGTACAGCC TGGAACCCTT TAGGAGAAGC AGCACCCCCA 
GGGGAGCTGT ACCGACGGAC CCTGGACTCA GATGAAGAGC GGCCCCGTCC CGCACCCCCA 
GACTGGTCAC ATATGCGTGG CATCATCAGC AGTGATGGCG AGAGTAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003600.2
CDS	13..1683
Translation	MAREKEMQEFTRSFFRGRPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPERKRFRFNSESESGSEASSPDYFGPPAKNGVAAEVSPAKEENPRRASKAVEESSDEERQRDLPAQRGEESSEEEEKGYKGKTRKKPVVKKQAPGKASVSRKQAREESEESEAEPVQRTAKKVEGNKGTKSLKESEQESEEEILAQKKEQREEEVEEEEKEEDEEKGDWKPRTRSNGRRKSAREERSCKQKSQAKRLLGDSDSEEEQKEAASSGDDSGRDREPPVQRKSEDRTQLKGGKRLSGSSEDEEDSGKGEPTAKGSRKMARLGSTSGEESDLEREVSDSEAGGGPQGERKNRSSKKSSRKGRTRSSSSSSDGSPEAKGGKAGSGRRGEDHPAVMRLKRYIRACGAHRNYKKLLGSCCSHKERLSILRAELEALGMKGTPSLGKCRALKEQREEAAEVASLDVANIISGSGRPRRRTAWNPLGEAAPPGELYRRTLDSDEERPRPAPPDWSHMRGIISSDGESN

Target ORF information:

RefSeq Version	NM_003609.5
Organism	Homo sapiens(human)
Definition	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003609.5

ORF Insert Sequence:

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GAGTCCGGCT CTGAAGCCTC CAGCCCAGAC TACTTTGGAC CCCCAGCAAA GAATGGGGTG 
GCAGCAGAAG TCAGCCCAGC CAAAGAGGAG AATCCAAGGC GAGCCTCAAA GGCAGTTGAG 
GAGAGCAGTG ATGAGGAACG GCAGAGGGAC CTGCCCGCAC AGAGGGGAGA GGAGAGCAGT 
GAGGAGGAGG AAAAGGGGTA CAAGGGGAAG ACTAGGAAGA AACCTGTGGT AAAGAAGCAG 
GCACCAGGCA AGGCCTCAGT CAGTAGGAAG CAGGCCAGGG AAGAAAGTGA GGAGAGCGAG 
GCAGAACCCG TTCAGAGGAC AGCAAAGAAG GTGGAGGGAA ATAAAGGAAC TAAAAGCCTG 
AAGGAAAGTG AACAGGAGAG TGAAGAGGAG ATCCTAGCCC AGAAGAAAGA GCAGAGAGAG 
GAGGAAGTGG AGGAGGAAGA GAAAGAAGAG GATGAGGAAA AGGGGGATTG GAAACCCAGA 
ACCAGGAGCA ATGGCCGGAG AAAGTCAGCT AGGGAGGAGA GGAGCTGTAA GCAGAAAAGC 
CAGGCAAAGA GGCTCTTGGG AGACTCAGAC AGCGAGGAAG AGCAGAAAGA GGCAGCCAGC 
AGTGGGGATG ACAGTGGGAG AGATAGAGAA CCCCCAGTGC AGAGGAAGAG TGAGGACAGG 
ACCCAGCTTA AGGGTGGGAA GAGGTTGAGT GGAAGCAGCG AGGACGAGGA AGACAGTGGG 
AAGGGGGAAC CCACAGCTAA AGGCTCTAGA AAGATGGCCA GACTGGGCAG CACCAGTGGT 
GAGGAAAGTG ACTTGGAGAG GGAGGTAAGT GACAGCGAGG CAGGGGGAGG CCCCCAGGGG 
GAGAGGAAGA ACCGCTCTTC CAAGAAGAGC TCCAGGAAAG GCAGGACACG AAGCTCCTCT 
TCCTCCTCAG ATGGAAGTCC AGAGGCCAAA GGAGGGAAGG CTGGCTCAGG TCGCCGTGGA 
GAGGACCACC CGGCTGTGAT GAGGCTGAAG CGCTACATTC GGGCCTGTGG TGCCCATCGA 
AACTACAAGA AGCTGTTGGG CTCCTGTTGC TCACACAAGG AGCGCCTGAG TATCCTCCGG 
GCAGAACTGG AAGCGCTAGG CATGAAGGGT ACCCCTTCCC TAGGGAAGTG TCGGGCCCTG 
AAGGAGCAGA GGGAGGAGGC AGCTGAGGTG GCCTCCTTGG ATGTTGCGAA CATCATCAGT 
GGCTCGGGCC GGCCACGCAG ACGTACAGCC TGGAACCCTT TAGGAGAAGC AGCACCCCCA 
GGGGAGCTGT ACCGACGGAC CCTGGACTCA GATGAAGAGC GGCCCCGTCC CGCACCCCCA 
GACTGGTCAC ATATGCGTGG CATCATCAGC AGTGATGGCG AGAGTAACTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HIRIP3 ( NM_001197323.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001184252.1 Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu55874
Clone ID Related Accession (Same CDS sequence)	NM_001197323.1
Accession Version	NM_001197323.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 528bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-04
Organism	Homo sapiens(human)
Product	HIRA-interacting protein 3 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA716463.1, BC000588.2, BE207110.1, Z25386.1, BU629222.1, BX101682.1 and BM673568.1. Transcript Variant: This variant (2) lacks an exon in the coding region, resulting in frame-shift, compared to variant 1. The resulting isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.87083.1, SRR1660803.17246.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GGCTGGCTCA GGTCGCCGTG GAGAGGACCA CCCGGCTGTG ATGAGGCTGA AGCGCTACAT 
TCGGGCCTGT GGTGCCCATC GAAACTACAA GAAGCTGTTG GGCTCCTGTT GCTCACACAA 
GGAGCGCCTG AGTATCCTCC GGGCAGAACT GGAAGCGCTA GGCATGAAGG GTACCCCTTC 
CCTAGGGAAG TGTCGGGCCC TGAAGGAGCA GAGGGAGGAG GCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001184252.1
CDS	492..1019
Translation	MAREKEMQEFTRSFFRGRPDLSTLTHSIVRRRYLAHSGRSHLEPEEKQALKRLVEEELLKMQVDEAASREDKLDLTKKGKRPPTPCSDPERKRFRFNSESGWLRSPWRGPPGCDEAEALHSGLWCPSKLQEAVGLLLLTQGAPEYPPGRTGSARHEGYPFPREVSGPEGAEGGGS

Target ORF information:

RefSeq Version	NM_001197323.1
Organism	Homo sapiens(human)
Definition	Homo sapiens HIRA interacting protein 3 (HIRIP3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001197323.1

ORF Insert Sequence:

ATGGCGCGGG AGAAGGAGAT GCAGGAGTTC ACCCGTAGCT TCTTCCGAGG CCGCCCGGAC 
CTCAGCACGC TTACGCATTC CATCGTGCGG CGGAGGTACT TAGCTCACTC GGGCCGCAGC 
CACCTGGAGC CCGAGGAGAA GCAGGCACTG AAGCGGCTGG TGGAGGAGGA GCTGCTGAAG 
ATGCAGGTGG ATGAAGCCGC TTCCAGGGAA GACAAACTGG ACCTTACCAA GAAGGGCAAG 
AGGCCTCCCA CCCCTTGTAG CGACCCGGAG AGAAAAAGGT TCCGCTTCAA TTCAGAGTCG 
GGCTGGCTCA GGTCGCCGTG GAGAGGACCA CCCGGCTGTG ATGAGGCTGA AGCGCTACAT 
TCGGGCCTGT GGTGCCCATC GAAACTACAA GAAGCTGTTG GGCTCCTGTT GCTCACACAA 
GGAGCGCCTG AGTATCCTCC GGGCAGAACT GGAAGCGCTA GGCATGAAGG GTACCCCTTC 
CCTAGGGAAG TGTCGGGCCC TGAAGGAGCA GAGGGAGGAG GCAGCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Biological insights from 108 schizophrenia-associated genetic loci.
Nature511(7510)421-7(2014 Jul)

Association and mutation analyses of 16p11.2 autism candidate genes.
PloS one4(2)e4582(2009)
Kumar RA,Marshall CR,Badner JA,Babatz TD,Mukamel Z,Aldinger KA,Sudi J,Brune CW,Goh G,Karamohamed S,Sutcliffe JS,Cook EH,Geschwind DH,Dobyns WB,Scherer SW,Christian SL

HIRIP3 is a nuclear phosphoprotein interacting with and phosphorylated by the serine-threonine kinase CK2.
Biological chemistry388(4)391-8(2007 Apr)
Assrir N,Filhol O,Galisson F,Lipinski M

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.
Nature biotechnology24(10)1285-92(2006 Oct)
Beausoleil SA,Vill?n J,Gerber SA,Rush J,Gygi SP

A germline-specific class of small RNAs binds mammalian Piwi proteins.
Nature442(7099)199-202(2006 Jul)
Girard A,Sachidanandam R,Hannon GJ,Carmell MA

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HIRIP3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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