HPS3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	HPS3
Entrez Gene ID	84343
Full Name	HPS3, biogenesis of lysosomal organelles complex 2 subunit 1
Synonyms	BLOC2S1,SUTAL
General protein information	Preferred Names HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 Names Hermansky-Pudlak syndrome 3 protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3q24
Summary	This gene encodes a protein containing a potential clathrin-binding motif, consensus dileucine signals, and tyrosine-based sorting signals for targeting to vesicles of lysosomal lineage. The encoded protein may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 3. [provided by RefSeq, Apr 2015].
Disorder MIM:	606118
Disorder Html:	Hermansky-Pudlak syndrome 3, 614072 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_017007323.1	XP_016862812.1	Hermansky-Pudlak syndrome 3 protein isoform X1
XM_005247834.3	XP_005247891.1	Hermansky-Pudlak syndrome 3 protein isoform X2
XM_005247834.4	XP_005247891.1	Hermansky-Pudlak syndrome 3 protein isoform X2
NM_032383.4	NP_115759.2	Hermansky-Pudlak syndrome 3 protein isoform 1
NM_032383.5	NP_115759.2	Hermansky-Pudlak syndrome 3 protein isoform 1
NM_001308258.1	NP_001295187.1	Hermansky-Pudlak syndrome 3 protein isoform 2
NM_001308258.2	NP_001295187.1	Hermansky-Pudlak syndrome 3 protein isoform 2
XM_017007323.2	XP_016862812.1	Hermansky-Pudlak syndrome 3 protein isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	HPS3	NP_001178106.1
Danio rerio (zebrafish)	hps3	NP_001180471.1
Pan troglodytes (chimpanzee)	HPS3	XP_001139589.1
	HPS3	XP_002803056.1
Canis lupus familiaris (dog)	HPS3	XP_542830.3
Mus musculus (house mouse)	Hps3	NP_542365.3
Homo sapiens (human)	HPS3	NP_115759.2
Rattus norvegicus (Norway rat)	Hps3	NP_001101134.1
Gallus gallus (chicken)	HPS3	XP_422849.2
Xenopus tropicalis (tropical clawed frog)	hps3	XP_002937376.2

Gene Ontology
Bibliography

Related articles in PubMed

NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients.
Wei A, Yuan Y, Bai D, Ma J, Hao Z, Zhang Y, Yu J, Zhou Z, Yang L, Yang X, Li L, Li W
Pigment cell & melanoma research29(6)702-706(2016 Nov)

HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes.
Li K, Yang L, Zhang C, Niu Y, Li W, Liu JJ
Journal of cell science127(Pt 21)4574-88(2014 Nov)

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor.
Gerondopoulos A, Langemeyer L, Liang JR, Linford A, Barr FA
Current biology : CB22(22)2135-9(2012 Nov)

Newborn screening for hermansky-pudlak syndrome type 3 in Puerto Rico.
Torres-Serrant M, Ramirez SI, Cadilla CL, Ramos-Valencia G, Santiago-Borrero PJ
Journal of pediatric hematology/oncology32(6)448-53(2010 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

HPS3 mutation is associated with high hypopigmentation in Hermansky-Pudlak syndrome.
Title: NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients.

Observational study of genotype prevalence. (HuGE Navigator)
Title: Newborn screening for hermansky-pudlak syndrome type 3 in Puerto Rico.

Observational study of genotype prevalence. (HuGE Navigator)
Title: Genetic testing for oculocutaneous albinism type 1 and 2 and Hermansky-Pudlak syndrome type 1 and 3 mutations in Puerto Rico.

HPS3 associates with clathrin, predominantly on small clathrin-containing vesicles in the perinuclear region. This association most likely occurs directly via a functional clathrin-binding domain in HPS3.
Title: Association of the Hermansky-Pudlak syndrome type-3 protein with clathrin.

A specific subset of melanocyte proteins are aberrantly trafficked throughout the HPS-3 melanocyte and may be responsible for the reduction in melanin synthesis.
Title: Melanocyte-specific proteins are aberrantly trafficked in melanocytes of Hermansky-Pudlak syndrome-type 3.

The following HPS3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HPS3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu73513	NM_001308258.2 Latest version!	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu38197	XM_005247834.4 Latest version!	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu94651	XM_017007323.2 Latest version!	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
OHu21086	NM_032383.5 Latest version!	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
View Old Accession Versions >>
OHu38197	XM_005247834.3	Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$391.30 $559.00
OHu21086	NM_032383.4	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$69.30 $99.00
OHu73513	NM_001308258.1	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu94651	XM_017007323.1	Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HPS3 ( NM_001308258.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295187.1 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu73513
Clone ID Related Accession (Same CDS sequence)	NM_001308258.1 , NM_001308258.2
Accession Version	NM_001308258.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2520bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-24
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY033141.1, BC022062.2 and CB241738.1. On Apr 28, 2015 this sequence version replaced XM_011513236.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.130858.1, AK298478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGCA TCAGTAATGA AATTTCACAG 
CTTGAGTCAG ATGATTTTGT CATCTGCCAG AAGCCCCTGG AACTTCTTGG TGAAAAAAGT 
GAACAGTCTG GATTATCTGT TACACTGGAG TCTACGGGAT TAGCTGATGA AAAAAGAAAA 
TATTCCCACT TTCAGCACCT GCTCTATAGA CGTTTTGCTC CTGATATTTC GTCCTATGTC 
TTGTCTGATG ACATCAAGCT ACATTCCCTC CAGCTGCTAC CCATTTACCA GACCGGTTCT 
CTTACATCTG ATGGAAAAAA TTTGTCTCAG GAAAAAGAAT TGCTGAGTCT CTTTTGCTTT 
TTCTCCTTAC CTCATGTGGG CTATCTCTAC ATGGTTGTCA AATCTGTTGA ATTGATGTCA 
GTCTACCAGT ATCCTGAAAA GTCTCAGCAG GCAGTACTCA CGCCACAATT TTTGCACGTC 
ATTACAAGTA ACAACCTGCA GTGTTTCACT GTGCGGTGCA GTGCGGCGGC AGCTCGTGAG 
GAGGACCCGT ACATGGACAC CACCCTGAAG GCTTGCCCAC CTGTCAGTAT GGATGTCTGT 
GCTTTAAGAA TACAGCTTTT CATAGGCTTG AAAGCCATCT GTCACTTTAA AAACCACATC 
ATACTTTTGA CTAAAGCAGA ACCTGAAGCC ATTCCAGAGA GAAGACAGTC ACCCAAGAGG 
CTTCTTTCGA GAAAAGATAC CAGTGTTAAA ATCAAAATAC CTCCTGTAGC TGAGGCTGGG 
TGGAATTTGT ATATTGTGAA TACGATCTCA CCAGTGCAGC TGTACAAAGA GATGGTAGAC 
TATAGCAATA CCTATAAGAC TGTCAAAACC CAGAGCTGCA TTCACCTTCT CAGTGAGGCT 
CATCTGTTAG TGCGAGCTGC CCTGATGGAT GCCAGTCAGC TGGAACCTGG AGAGAAGGCA 
GAGCTTTTGG AAGCATTTAA GGAAAGCTGT GGGCACCTTG GGGACTGTTA CAGCAGGCTT 
GACTCCCAGC ATTCTCATCT CACCTTGCCA TACTATAAGA TGTCTGGTTT GTCTATGGCT 
GAAGTTCTGG CCCGCACGGA CTGGACAGTA GAGGATGGAT TACAGAAATA CGAGAGAGGA 
TTAATCTTTT ACATTAATCA TTCACTTTAT GAAAACCTGG ATGAAGAATT AAATGAAGAA 
TTAGCAGCAA AAGTGGTTCA GATGTTTTAT GTGGCTGAGC CAAAGCAAGT GCCCCATATT 
CTCTGTAGTC CTTCTATGAA GAATATTAAT CCTTTAACTG CCATGAGCTA TCTAAGGAAG 
CTGGATACTT CTGGGTTTTC ATCGATCTTA GTGACATTGA CCAAGGCAGC AGTGGCTCTG 
AAAATGGGAG ATCTTGACAT GCACAGAAAT GAAATGAAAA GCCATTCAGA GATGAAGTTG 
GTATGTGGCT TCATTCTGGA ACCTCGGCTG TTGATTCAAC AGAGAAAGGG ACAGATTGTT 
CCAACCGAGC TTGCACTTCA CTTGAAGGAA ACTCAGCCTG GATTGCTTGT GGCTTCAGTT 
CTGGGCTTGC AGAAGAACAA CAAAATTGGA ATTGAAGAAG CAGATTCCTT TTTTAAGGTG 
CTTTGTGCTA AGGATGAAGA TACAATTCCT CAGCTCTTGG TAGACTTTTG GGAAGCTCAG 
CTAGTGGCAT GTCTCCCAGA TGTGGTACTT CAGGAACTCT TTTTCAAACT CACATCACAG 
TACATCTGGA GATTGTCTAA GAGGCAGCCT CCTGACACCA CACCATTGCG AACATCGGAG 
GATCTGATAA ATGCCTGTAG TCATTATGGC TTAATTTATC CATGGGTTCA CGTCGTAATA 
TCATCTGATT CTTTAGCTGA TAAAAATTAT ACAGAAGATC TTTCAAAATT ACAGTCTCTT 
ATATGTGGTC CTTCATTTGA CATAGCTTCC ATTATTCCGT TCTTGGAGCC ACTTTCAGAA 
GACACTATTG CCGGCCTCAG TGTCCATGTT CTGTGTCGTA CACGCTTGAA AGAGTATGAA 
CAGTGCATAG ACATACTGTT AGAGAGATGC CCGGAGGCAG TCATTCCATA TGCTAATCAT 
GAACTGAAAG AAGAGAACCG GACTCTGTGG TGGAAAAAAC TGTTGCCTGA ACTTTGTCAG 
AGAATAAAAT GTGGTGGAGA GAAGTATCAA CTCTACCTGT CATCATTAAA AGAAACATTG 
TCAATTGTTG CTGTGGAACT AGAACTGAAG GATTTCATGA ATGTTCTCCC AGAAGATGGT 
ACTGCAACAT TTTTCTTGCC ATATCTTCTC TATTGCAGTC GAAAGAAACC ATTGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295187.1
CDS	141..2660
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT

Target ORF information:

RefSeq Version	NM_001308258.1
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308258.1

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGCA TCAGTAATGA AATTTCACAG 
CTTGAGTCAG ATGATTTTGT CATCTGCCAG AAGCCCCTGG AACTTCTTGG TGAAAAAAGT 
GAACAGTCTG GATTATCTGT TACACTGGAG TCTACGGGAT TAGCTGATGA AAAAAGAAAA 
TATTCCCACT TTCAGCACCT GCTCTATAGA CGTTTTGCTC CTGATATTTC GTCCTATGTC 
TTGTCTGATG ACATCAAGCT ACATTCCCTC CAGCTGCTAC CCATTTACCA GACCGGTTCT 
CTTACATCTG ATGGAAAAAA TTTGTCTCAG GAAAAAGAAT TGCTGAGTCT CTTTTGCTTT 
TTCTCCTTAC CTCATGTGGG CTATCTCTAC ATGGTTGTCA AATCTGTTGA ATTGATGTCA 
GTCTACCAGT ATCCTGAAAA GTCTCAGCAG GCAGTACTCA CGCCACAATT TTTGCACGTC 
ATTACAAGTA ACAACCTGCA GTGTTTCACT GTGCGGTGCA GTGCGGCGGC AGCTCGTGAG 
GAGGACCCGT ACATGGACAC CACCCTGAAG GCTTGCCCAC CTGTCAGTAT GGATGTCTGT 
GCTTTAAGAA TACAGCTTTT CATAGGCTTG AAAGCCATCT GTCACTTTAA AAACCACATC 
ATACTTTTGA CTAAAGCAGA ACCTGAAGCC ATTCCAGAGA GAAGACAGTC ACCCAAGAGG 
CTTCTTTCGA GAAAAGATAC CAGTGTTAAA ATCAAAATAC CTCCTGTAGC TGAGGCTGGG 
TGGAATTTGT ATATTGTGAA TACGATCTCA CCAGTGCAGC TGTACAAAGA GATGGTAGAC 
TATAGCAATA CCTATAAGAC TGTCAAAACC CAGAGCTGCA TTCACCTTCT CAGTGAGGCT 
CATCTGTTAG TGCGAGCTGC CCTGATGGAT GCCAGTCAGC TGGAACCTGG AGAGAAGGCA 
GAGCTTTTGG AAGCATTTAA GGAAAGCTGT GGGCACCTTG GGGACTGTTA CAGCAGGCTT 
GACTCCCAGC ATTCTCATCT CACCTTGCCA TACTATAAGA TGTCTGGTTT GTCTATGGCT 
GAAGTTCTGG CCCGCACGGA CTGGACAGTA GAGGATGGAT TACAGAAATA CGAGAGAGGA 
TTAATCTTTT ACATTAATCA TTCACTTTAT GAAAACCTGG ATGAAGAATT AAATGAAGAA 
TTAGCAGCAA AAGTGGTTCA GATGTTTTAT GTGGCTGAGC CAAAGCAAGT GCCCCATATT 
CTCTGTAGTC CTTCTATGAA GAATATTAAT CCTTTAACTG CCATGAGCTA TCTAAGGAAG 
CTGGATACTT CTGGGTTTTC ATCGATCTTA GTGACATTGA CCAAGGCAGC AGTGGCTCTG 
AAAATGGGAG ATCTTGACAT GCACAGAAAT GAAATGAAAA GCCATTCAGA GATGAAGTTG 
GTATGTGGCT TCATTCTGGA ACCTCGGCTG TTGATTCAAC AGAGAAAGGG ACAGATTGTT 
CCAACCGAGC TTGCACTTCA CTTGAAGGAA ACTCAGCCTG GATTGCTTGT GGCTTCAGTT 
CTGGGCTTGC AGAAGAACAA CAAAATTGGA ATTGAAGAAG CAGATTCCTT TTTTAAGGTG 
CTTTGTGCTA AGGATGAAGA TACAATTCCT CAGCTCTTGG TAGACTTTTG GGAAGCTCAG 
CTAGTGGCAT GTCTCCCAGA TGTGGTACTT CAGGAACTCT TTTTCAAACT CACATCACAG 
TACATCTGGA GATTGTCTAA GAGGCAGCCT CCTGACACCA CACCATTGCG AACATCGGAG 
GATCTGATAA ATGCCTGTAG TCATTATGGC TTAATTTATC CATGGGTTCA CGTCGTAATA 
TCATCTGATT CTTTAGCTGA TAAAAATTAT ACAGAAGATC TTTCAAAATT ACAGTCTCTT 
ATATGTGGTC CTTCATTTGA CATAGCTTCC ATTATTCCGT TCTTGGAGCC ACTTTCAGAA 
GACACTATTG CCGGCCTCAG TGTCCATGTT CTGTGTCGTA CACGCTTGAA AGAGTATGAA 
CAGTGCATAG ACATACTGTT AGAGAGATGC CCGGAGGCAG TCATTCCATA TGCTAATCAT 
GAACTGAAAG AAGAGAACCG GACTCTGTGG TGGAAAAAAC TGTTGCCTGA ACTTTGTCAG 
AGAATAAAAT GTGGTGGAGA GAAGTATCAA CTCTACCTGT CATCATTAAA AGAAACATTG 
TCAATTGTTG CTGTGGAACT AGAACTGAAG GATTTCATGA ATGTTCTCCC AGAAGATGGT 
ACTGCAACAT TTTTCTTGCC ATATCTTCTC TATTGCAGTC GAAAGAAACC ATTGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( NM_001308258.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001295187.1 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu73513
Clone ID Related Accession (Same CDS sequence)	NM_001308258.1 , NM_001308258.2
Accession Version	NM_001308258.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2520bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY033141.1, BC022062.2, CB241738.1 and AC131209.2. On May 31, 2019 this sequence version replaced NM_001308258.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. It encodes isoform 2 which is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.130858.1, AK298478.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGCA TCAGTAATGA AATTTCACAG 
CTTGAGTCAG ATGATTTTGT CATCTGCCAG AAGCCCCTGG AACTTCTTGG TGAAAAAAGT 
GAACAGTCTG GATTATCTGT TACACTGGAG TCTACGGGAT TAGCTGATGA AAAAAGAAAA 
TATTCCCACT TTCAGCACCT GCTCTATAGA CGTTTTGCTC CTGATATTTC GTCCTATGTC 
TTGTCTGATG ACATCAAGCT ACATTCCCTC CAGCTGCTAC CCATTTACCA GACCGGTTCT 
CTTACATCTG ATGGAAAAAA TTTGTCTCAG GAAAAAGAAT TGCTGAGTCT CTTTTGCTTT 
TTCTCCTTAC CTCATGTGGG CTATCTCTAC ATGGTTGTCA AATCTGTTGA ATTGATGTCA 
GTCTACCAGT ATCCTGAAAA GTCTCAGCAG GCAGTACTCA CGCCACAATT TTTGCACGTC 
ATTACAAGTA ACAACCTGCA GTGTTTCACT GTGCGGTGCA GTGCGGCGGC AGCTCGTGAG 
GAGGACCCGT ACATGGACAC CACCCTGAAG GCTTGCCCAC CTGTCAGTAT GGATGTCTGT 
GCTTTAAGAA TACAGCTTTT CATAGGCTTG AAAGCCATCT GTCACTTTAA AAACCACATC 
ATACTTTTGA CTAAAGCAGA ACCTGAAGCC ATTCCAGAGA GAAGACAGTC ACCCAAGAGG 
CTTCTTTCGA GAAAAGATAC CAGTGTTAAA ATCAAAATAC CTCCTGTAGC TGAGGCTGGG 
TGGAATTTGT ATATTGTGAA TACGATCTCA CCAGTGCAGC TGTACAAAGA GATGGTAGAC 
TATAGCAATA CCTATAAGAC TGTCAAAACC CAGAGCTGCA TTCACCTTCT CAGTGAGGCT 
CATCTGTTAG TGCGAGCTGC CCTGATGGAT GCCAGTCAGC TGGAACCTGG AGAGAAGGCA 
GAGCTTTTGG AAGCATTTAA GGAAAGCTGT GGGCACCTTG GGGACTGTTA CAGCAGGCTT 
GACTCCCAGC ATTCTCATCT CACCTTGCCA TACTATAAGA TGTCTGGTTT GTCTATGGCT 
GAAGTTCTGG CCCGCACGGA CTGGACAGTA GAGGATGGAT TACAGAAATA CGAGAGAGGA 
TTAATCTTTT ACATTAATCA TTCACTTTAT GAAAACCTGG ATGAAGAATT AAATGAAGAA 
TTAGCAGCAA AAGTGGTTCA GATGTTTTAT GTGGCTGAGC CAAAGCAAGT GCCCCATATT 
CTCTGTAGTC CTTCTATGAA GAATATTAAT CCTTTAACTG CCATGAGCTA TCTAAGGAAG 
CTGGATACTT CTGGGTTTTC ATCGATCTTA GTGACATTGA CCAAGGCAGC AGTGGCTCTG 
AAAATGGGAG ATCTTGACAT GCACAGAAAT GAAATGAAAA GCCATTCAGA GATGAAGTTG 
GTATGTGGCT TCATTCTGGA ACCTCGGCTG TTGATTCAAC AGAGAAAGGG ACAGATTGTT 
CCAACCGAGC TTGCACTTCA CTTGAAGGAA ACTCAGCCTG GATTGCTTGT GGCTTCAGTT 
CTGGGCTTGC AGAAGAACAA CAAAATTGGA ATTGAAGAAG CAGATTCCTT TTTTAAGGTG 
CTTTGTGCTA AGGATGAAGA TACAATTCCT CAGCTCTTGG TAGACTTTTG GGAAGCTCAG 
CTAGTGGCAT GTCTCCCAGA TGTGGTACTT CAGGAACTCT TTTTCAAACT CACATCACAG 
TACATCTGGA GATTGTCTAA GAGGCAGCCT CCTGACACCA CACCATTGCG AACATCGGAG 
GATCTGATAA ATGCCTGTAG TCATTATGGC TTAATTTATC CATGGGTTCA CGTCGTAATA 
TCATCTGATT CTTTAGCTGA TAAAAATTAT ACAGAAGATC TTTCAAAATT ACAGTCTCTT 
ATATGTGGTC CTTCATTTGA CATAGCTTCC ATTATTCCGT TCTTGGAGCC ACTTTCAGAA 
GACACTATTG CCGGCCTCAG TGTCCATGTT CTGTGTCGTA CACGCTTGAA AGAGTATGAA 
CAGTGCATAG ACATACTGTT AGAGAGATGC CCGGAGGCAG TCATTCCATA TGCTAATCAT 
GAACTGAAAG AAGAGAACCG GACTCTGTGG TGGAAAAAAC TGTTGCCTGA ACTTTGTCAG 
AGAATAAAAT GTGGTGGAGA GAAGTATCAA CTCTACCTGT CATCATTAAA AGAAACATTG 
TCAATTGTTG CTGTGGAACT AGAACTGAAG GATTTCATGA ATGTTCTCCC AGAAGATGGT 
ACTGCAACAT TTTTCTTGCC ATATCTTCTC TATTGCAGTC GAAAGAAACC ATTGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001295187.1
CDS	87..2606
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT

Target ORF information:

RefSeq Version	NM_001308258.2
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001308258.2

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGCA TCAGTAATGA AATTTCACAG 
CTTGAGTCAG ATGATTTTGT CATCTGCCAG AAGCCCCTGG AACTTCTTGG TGAAAAAAGT 
GAACAGTCTG GATTATCTGT TACACTGGAG TCTACGGGAT TAGCTGATGA AAAAAGAAAA 
TATTCCCACT TTCAGCACCT GCTCTATAGA CGTTTTGCTC CTGATATTTC GTCCTATGTC 
TTGTCTGATG ACATCAAGCT ACATTCCCTC CAGCTGCTAC CCATTTACCA GACCGGTTCT 
CTTACATCTG ATGGAAAAAA TTTGTCTCAG GAAAAAGAAT TGCTGAGTCT CTTTTGCTTT 
TTCTCCTTAC CTCATGTGGG CTATCTCTAC ATGGTTGTCA AATCTGTTGA ATTGATGTCA 
GTCTACCAGT ATCCTGAAAA GTCTCAGCAG GCAGTACTCA CGCCACAATT TTTGCACGTC 
ATTACAAGTA ACAACCTGCA GTGTTTCACT GTGCGGTGCA GTGCGGCGGC AGCTCGTGAG 
GAGGACCCGT ACATGGACAC CACCCTGAAG GCTTGCCCAC CTGTCAGTAT GGATGTCTGT 
GCTTTAAGAA TACAGCTTTT CATAGGCTTG AAAGCCATCT GTCACTTTAA AAACCACATC 
ATACTTTTGA CTAAAGCAGA ACCTGAAGCC ATTCCAGAGA GAAGACAGTC ACCCAAGAGG 
CTTCTTTCGA GAAAAGATAC CAGTGTTAAA ATCAAAATAC CTCCTGTAGC TGAGGCTGGG 
TGGAATTTGT ATATTGTGAA TACGATCTCA CCAGTGCAGC TGTACAAAGA GATGGTAGAC 
TATAGCAATA CCTATAAGAC TGTCAAAACC CAGAGCTGCA TTCACCTTCT CAGTGAGGCT 
CATCTGTTAG TGCGAGCTGC CCTGATGGAT GCCAGTCAGC TGGAACCTGG AGAGAAGGCA 
GAGCTTTTGG AAGCATTTAA GGAAAGCTGT GGGCACCTTG GGGACTGTTA CAGCAGGCTT 
GACTCCCAGC ATTCTCATCT CACCTTGCCA TACTATAAGA TGTCTGGTTT GTCTATGGCT 
GAAGTTCTGG CCCGCACGGA CTGGACAGTA GAGGATGGAT TACAGAAATA CGAGAGAGGA 
TTAATCTTTT ACATTAATCA TTCACTTTAT GAAAACCTGG ATGAAGAATT AAATGAAGAA 
TTAGCAGCAA AAGTGGTTCA GATGTTTTAT GTGGCTGAGC CAAAGCAAGT GCCCCATATT 
CTCTGTAGTC CTTCTATGAA GAATATTAAT CCTTTAACTG CCATGAGCTA TCTAAGGAAG 
CTGGATACTT CTGGGTTTTC ATCGATCTTA GTGACATTGA CCAAGGCAGC AGTGGCTCTG 
AAAATGGGAG ATCTTGACAT GCACAGAAAT GAAATGAAAA GCCATTCAGA GATGAAGTTG 
GTATGTGGCT TCATTCTGGA ACCTCGGCTG TTGATTCAAC AGAGAAAGGG ACAGATTGTT 
CCAACCGAGC TTGCACTTCA CTTGAAGGAA ACTCAGCCTG GATTGCTTGT GGCTTCAGTT 
CTGGGCTTGC AGAAGAACAA CAAAATTGGA ATTGAAGAAG CAGATTCCTT TTTTAAGGTG 
CTTTGTGCTA AGGATGAAGA TACAATTCCT CAGCTCTTGG TAGACTTTTG GGAAGCTCAG 
CTAGTGGCAT GTCTCCCAGA TGTGGTACTT CAGGAACTCT TTTTCAAACT CACATCACAG 
TACATCTGGA GATTGTCTAA GAGGCAGCCT CCTGACACCA CACCATTGCG AACATCGGAG 
GATCTGATAA ATGCCTGTAG TCATTATGGC TTAATTTATC CATGGGTTCA CGTCGTAATA 
TCATCTGATT CTTTAGCTGA TAAAAATTAT ACAGAAGATC TTTCAAAATT ACAGTCTCTT 
ATATGTGGTC CTTCATTTGA CATAGCTTCC ATTATTCCGT TCTTGGAGCC ACTTTCAGAA 
GACACTATTG CCGGCCTCAG TGTCCATGTT CTGTGTCGTA CACGCTTGAA AGAGTATGAA 
CAGTGCATAG ACATACTGTT AGAGAGATGC CCGGAGGCAG TCATTCCATA TGCTAATCAT 
GAACTGAAAG AAGAGAACCG GACTCTGTGG TGGAAAAAAC TGTTGCCTGA ACTTTGTCAG 
AGAATAAAAT GTGGTGGAGA GAAGTATCAA CTCTACCTGT CATCATTAAA AGAAACATTG 
TCAATTGTTG CTGTGGAACT AGAACTGAAG GATTTCATGA ATGTTCTCCC AGAAGATGGT 
ACTGCAACAT TTTTCTTGCC ATATCTTCTC TATTGCAGTC GAAAGAAACC ATTGACTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( XM_005247834.3 ) cDNA ORF clone, Homo sapiens(human) -> XP_005247891.1 Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu38197
Clone ID Related Accession (Same CDS sequence)	XM_005247834.3 , XM_005247834.4
Accession Version	XM_005247834.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced XM_005247834.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005247891.1
CDS	116..2407
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFF

Target ORF information:

RefSeq Version	XM_005247834.3
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005247834.3

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( XM_005247834.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005247891.1 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.

Price & Availability↑

CloneID	OHu38197
Clone ID Related Accession (Same CDS sequence)	XM_005247834.3 , XM_005247834.4
Accession Version	XM_005247834.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2292bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_005247834.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005247891.1
CDS	100..2391
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFF

Target ORF information:

RefSeq Version	XM_005247834.4
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005247834.4

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( XM_017007323.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862812.1 Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu94651
Clone ID Related Accession (Same CDS sequence)	XM_017007323.1 , XM_017007323.2
Accession Version	XM_017007323.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862812.1
CDS	116..3007
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKA

Target ORF information:

RefSeq Version	XM_017007323.1
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3, biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007323.1

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( XM_017007323.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_016862812.1 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu94651
Clone ID Related Accession (Same CDS sequence)	XM_017007323.1 , XM_017007323.2
Accession Version	XM_017007323.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2892bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017007323.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016862812.1
CDS	101..2992
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKA

Target ORF information:

RefSeq Version	XM_017007323.2
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017007323.2

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGCTT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( NM_032383.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_115759.2 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21086
Clone ID Related Accession (Same CDS sequence)	NM_032383.4 , NM_032383.5
Accession Version	NM_032383.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3015bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-25
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY033141.1, BC022062.2 and CB241738.1. This sequence is a reference standard in the RefSeqGene project. On Apr 28, 2015 this sequence version replaced NM_032383.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY033141.1, SRR1660809.21747.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGAAA CATTGTCAAT TGTTGCTGTG GAACTAGAAC TGAAGGATTT CATGAATGTT 
CTCCCAGAAG ATGGTACTGC AACATTTTTC TTGCCATATC TTCTCTATTG CAGTCGAAAG 
AAACCATTGA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115759.2
CDS	141..3155
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT

Target ORF information:

RefSeq Version	NM_032383.4
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032383.4

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGAAA CATTGTCAAT TGTTGCTGTG GAACTAGAAC TGAAGGATTT CATGAATGTT 
CTCCCAGAAG ATGGTACTGC AACATTTTTC TTGCCATATC TTCTCTATTG CAGTCGAAAG 
AAACCATTGA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HPS3 ( NM_032383.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_115759.2 Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21086
Clone ID Related Accession (Same CDS sequence)	NM_032383.4 , NM_032383.5
Accession Version	NM_032383.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3015bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-25
Organism	Homo sapiens(human)
Product	Hermansky-Pudlak syndrome 3 protein isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY033141.1, BC022062.2, CB241738.1 and AC131209.2. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_032383.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.74487.1, SRR7346977.1794423.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000296051.7/ ENSP00000296051.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGAAA CATTGTCAAT TGTTGCTGTG GAACTAGAAC TGAAGGATTT CATGAATGTT 
CTCCCAGAAG ATGGTACTGC AACATTTTTC TTGCCATATC TTCTCTATTG CAGTCGAAAG 
AAACCATTGA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115759.2
CDS	87..3101
Translation	MVQLYNLHPFGSQQVVPCKLEPDRFCGGGRDALFVAAGCKVEAFAVAGQELCQPRCAFSTLGRVLRLAYSEAGDYLVAIEEKNKATFLRAYVNWRNKRTENSRVCIRMIGHNVEGPFSKAFRDQMYIIEMPLSEAPLCISCCPVKGDLLVGCTNKLVLFSLKYQIINEEFSLLDFERSLIIHIDNITPVEVSFCVGYVAVMSDLEVLIVKLESGPKNGERVHHHPHKTNNRIRRTEEGISNEISQLESDDFVICQKPLELLGEKSEQSGLSVTLESTGLADEKRKYSHFQHLLYRRFAPDISSYVLSDDIKLHSLQLLPIYQTGSLTSDGKNLSQEKELLSLFCFFSLPHVGYLYMVVKSVELMSVYQYPEKSQQAVLTPQFLHVITSNNLQCFTVRCSAAAAREEDPYMDTTLKACPPVSMDVCALRIQLFIGLKAICHFKNHIILLTKAEPEAIPERRQSPKRLLSRKDTSVKIKIPPVAEAGWNLYIVNTISPVQLYKEMVDYSNTYKTVKTQSCIHLLSEAHLLVRAALMDASQLEPGEKAELLEAFKESCGHLGDCYSRLDSQHSHLTLPYYKMSGLSMAEVLARTDWTVEDGLQKYERGLIFYINHSLYENLDEELNEELAAKVVQMFYVAEPKQVPHILCSPSMKNINPLTAMSYLRKLDTSGFSSILVTLTKAAVALKMGDLDMHRNEMKSHSEMKLVCGFILEPRLLIQQRKGQIVPTELALHLKETQPGLLVASVLGLQKNNKIGIEEADSFFKVLCAKDEDTIPQLLVDFWEAQLVACLPDVVLQELFFKLTSQYIWRLSKRQPPDTTPLRTSEDLINACSHYGLIYPWVHVVISSDSLADKNYTEDLSKLQSLICGPSFDIASIIPFLEPLSEDTIAGLSVHVLCRTRLKEYEQCIDILLERCPEAVIPYANHELKEENRTLWWKKLLPELCQRIKCGGEKYQLYLSSLKETLSIVAVELELKDFMNVLPEDGTATFFLPYLLYCSRKKPLT

Target ORF information:

RefSeq Version	NM_032383.5
Organism	Homo sapiens(human)
Definition	Homo sapiens HPS3 biogenesis of lysosomal organelles complex 2 subunit 1 (HPS3), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032383.5

ORF Insert Sequence:

ATGGTGCAGC TGTACAACCT GCACCCGTTC GGGTCGCAGC AGGTGGTGCC CTGCAAGCTG 
GAGCCGGACC GGTTCTGTGG CGGGGGGCGT GACGCGCTTT TCGTGGCGGC GGGCTGCAAG 
GTGGAGGCGT TCGCGGTGGC CGGCCAGGAG CTGTGCCAGC CGCGGTGCGC CTTCTCCACG 
CTGGGCCGGG TGTTGCGCCT GGCCTACAGC GAGGCTGGAG ATTATTTGGT AGCAATTGAA 
GAGAAAAACA AAGCTACATT TCTACGTGCT TATGTGAACT GGAGAAATAA AAGGACTGAA 
AACTCTCGTG TGTGTATCCG AATGATTGGG CATAATGTGG AGGGACCATT CAGCAAAGCC 
TTCAGAGACC AGATGTACAT TATTGAAATG CCGCTTTCGG AGGCCCCCTT GTGCATTTCC 
TGTTGCCCTG TGAAAGGAGA CCTTCTCGTT GGCTGCACAA ATAAATTAGT CTTATTTAGT 
TTGAAGTACC AGATCATTAA TGAGGAATTC TCACTATTGG ACTTTGAACG TTCTTTAATT 
ATACACATAG ATAATATCAC TCCTGTTGAG GTTTCTTTTT GTGTTGGATA TGTTGCTGTC 
ATGTCAGACT TAGAAGTCTT AATCGTAAAA CTGGAGTCAG GCCCTAAAAA TGGAGAGAGA 
GTTCACCACC ATCCACATAA GACCAACAAT CGAATAAGAC GGACAGAAGA AGGCATCAGT 
AATGAAATTT CACAGCTTGA GTCAGATGAT TTTGTCATCT GCCAGAAGCC CCTGGAACTT 
CTTGGTGAAA AAAGTGAACA GTCTGGATTA TCTGTTACAC TGGAGTCTAC GGGATTAGCT 
GATGAAAAAA GAAAATATTC CCACTTTCAG CACCTGCTCT ATAGACGTTT TGCTCCTGAT 
ATTTCGTCCT ATGTCTTGTC TGATGACATC AAGCTACATT CCCTCCAGCT GCTACCCATT 
TACCAGACCG GTTCTCTTAC ATCTGATGGA AAAAATTTGT CTCAGGAAAA AGAATTGCTG 
AGTCTCTTTT GCTTTTTCTC CTTACCTCAT GTGGGCTATC TCTACATGGT TGTCAAATCT 
GTTGAATTGA TGTCAGTCTA CCAGTATCCT GAAAAGTCTC AGCAGGCAGT ACTCACGCCA 
CAATTTTTGC ACGTCATTAC AAGTAACAAC CTGCAGTGTT TCACTGTGCG GTGCAGTGCG 
GCGGCAGCTC GTGAGGAGGA CCCGTACATG GACACCACCC TGAAGGCTTG CCCACCTGTC 
AGTATGGATG TCTGTGCTTT AAGAATACAG CTTTTCATAG GCTTGAAAGC CATCTGTCAC 
TTTAAAAACC ACATCATACT TTTGACTAAA GCAGAACCTG AAGCCATTCC AGAGAGAAGA 
CAGTCACCCA AGAGGCTTCT TTCGAGAAAA GATACCAGTG TTAAAATCAA AATACCTCCT 
GTAGCTGAGG CTGGGTGGAA TTTGTATATT GTGAATACGA TCTCACCAGT GCAGCTGTAC 
AAAGAGATGG TAGACTATAG CAATACCTAT AAGACTGTCA AAACCCAGAG CTGCATTCAC 
CTTCTCAGTG AGGCTCATCT GTTAGTGCGA GCTGCCCTGA TGGATGCCAG TCAGCTGGAA 
CCTGGAGAGA AGGCAGAGCT TTTGGAAGCA TTTAAGGAAA GCTGTGGGCA CCTTGGGGAC 
TGTTACAGCA GGCTTGACTC CCAGCATTCT CATCTCACCT TGCCATACTA TAAGATGTCT 
GGTTTGTCTA TGGCTGAAGT TCTGGCCCGC ACGGACTGGA CAGTAGAGGA TGGATTACAG 
AAATACGAGA GAGGATTAAT CTTTTACATT AATCATTCAC TTTATGAAAA CCTGGATGAA 
GAATTAAATG AAGAATTAGC AGCAAAAGTG GTTCAGATGT TTTATGTGGC TGAGCCAAAG 
CAAGTGCCCC ATATTCTCTG TAGTCCTTCT ATGAAGAATA TTAATCCTTT AACTGCCATG 
AGCTATCTAA GGAAGCTGGA TACTTCTGGG TTTTCATCGA TCTTAGTGAC ATTGACCAAG 
GCAGCAGTGG CTCTGAAAAT GGGAGATCTT GACATGCACA GAAATGAAAT GAAAAGCCAT 
TCAGAGATGA AGTTGGTATG TGGCTTCATT CTGGAACCTC GGCTGTTGAT TCAACAGAGA 
AAGGGACAGA TTGTTCCAAC CGAGCTTGCA CTTCACTTGA AGGAAACTCA GCCTGGATTG 
CTTGTGGCTT CAGTTCTGGG CTTGCAGAAG AACAACAAAA TTGGAATTGA AGAAGCAGAT 
TCCTTTTTTA AGGTGCTTTG TGCTAAGGAT GAAGATACAA TTCCTCAGCT CTTGGTAGAC 
TTTTGGGAAG CTCAGCTAGT GGCATGTCTC CCAGATGTGG TACTTCAGGA ACTCTTTTTC 
AAACTCACAT CACAGTACAT CTGGAGATTG TCTAAGAGGC AGCCTCCTGA CACCACACCA 
TTGCGAACAT CGGAGGATCT GATAAATGCC TGTAGTCATT ATGGCTTAAT TTATCCATGG 
GTTCACGTCG TAATATCATC TGATTCTTTA GCTGATAAAA ATTATACAGA AGATCTTTCA 
AAATTACAGT CTCTTATATG TGGTCCTTCA TTTGACATAG CTTCCATTAT TCCGTTCTTG 
GAGCCACTTT CAGAAGACAC TATTGCCGGC CTCAGTGTCC ATGTTCTGTG TCGTACACGC 
TTGAAAGAGT ATGAACAGTG CATAGACATA CTGTTAGAGA GATGCCCGGA GGCAGTCATT 
CCATATGCTA ATCATGAACT GAAAGAAGAG AACCGGACTC TGTGGTGGAA AAAACTGTTG 
CCTGAACTTT GTCAGAGAAT AAAATGTGGT GGAGAGAAGT ATCAACTCTA CCTGTCATCA 
TTAAAAGAAA CATTGTCAAT TGTTGCTGTG GAACTAGAAC TGAAGGATTT CATGAATGTT 
CTCCCAGAAG ATGGTACTGC AACATTTTTC TTGCCATATC TTCTCTATTG CAGTCGAAAG 
AAACCATTGA CTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

NGS-based 100-gene panel of hypopigmentation identifies mutations in Chinese Hermansky-Pudlak syndrome patients.
Pigment cell & melanoma research29(6)702-706(2016 Nov)
Wei A,Yuan Y,Bai D,Ma J,Hao Z,Zhang Y,Yu J,Zhou Z,Yang L,Yang X,Li L,Li W

HPS6 interacts with dynactin p150Glued to mediate retrograde trafficking and maturation of lysosomes.
Journal of cell science127(Pt 21)4574-88(2014 Nov)
Li K,Yang L,Zhang C,Niu Y,Li W,Liu JJ

BLOC-3 mutated in Hermansky-Pudlak syndrome is a Rab32/38 guanine nucleotide exchange factor.
Current biology : CB22(22)2135-9(2012 Nov)
Gerondopoulos A,Langemeyer L,Liang JR,Linford A,Barr FA

Newborn screening for hermansky-pudlak syndrome type 3 in Puerto Rico.
Journal of pediatric hematology/oncology32(6)448-53(2010 Aug)
Torres-Serrant M,Ramirez SI,Cadilla CL,Ramos-Valencia G,Santiago-Borrero PJ

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HPS3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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