KAT8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	KAT8
Entrez Gene ID	84148
Full Name	lysine acetyltransferase 8
Synonyms	MOF,MYST1,ZC2HC8,hMOF
General protein information	Preferred Names lysine acetyltransferase 8 Names histone acetyltransferase KAT8 K(lysine) acetyltransferase 8 MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1 MYST histone acetyltransferase 1 MYST-1 histone acetyltransferase MYST1 ortholog of Drosophila males absent on the first (MOF) probable histone acetyltransferase MYST1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 16 Map Location: 16p11.2
Summary	This gene encodes a member of the MYST histone acetylase protein family. The encoded protein has a characteristic MYST domain containing an acetyl-CoA-binding site, a chromodomain typical of proteins which bind histones, and a C2HC-type zinc finger. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2012].
Disorder MIM:	609912

mRNA and Protein(s)

mRNA	Protein	Name
NM_182958.3	NP_892003.2	histone acetyltransferase KAT8 isoform 2
NM_032188.3	NP_115564.2	histone acetyltransferase KAT8 isoform 1
NM_182958.2	NP_892003.2	histone acetyltransferase KAT8 isoform 2
NM_032188.2	NP_115564.2	histone acetyltransferase KAT8 isoform 1
XM_011545971.1	XP_011544273.1	histone acetyltransferase KAT8 isoform X1
XM_011545970.1	XP_011544272.1	histone acetyltransferase KAT8 isoform X1

Pathways from BioSystems

Homologies

Homo sapiens (human)	KAT8	NP_115564.2
Bos taurus (cattle)	KAT8	NP_001098953.1
Mus musculus (house mouse)	Kat8	NP_080646.1
Xenopus tropicalis (tropical clawed frog)	kat8	NP_001016234.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012229	XP_320309.4
Caenorhabditis elegans (roundworm)	mys-2	NP_493467.1
Arabidopsis thaliana (thale cress)	HAM2	NP_196536.1
Canis lupus familiaris (dog)	KAT8	XP_536904.2
Danio rerio (zebrafish)	kat8	NP_997907.1
Arabidopsis thaliana (thale cress)	HAM1	NP_201266.1
Pan troglodytes (chimpanzee)	KAT8	XP_523493.4
Rattus norvegicus (Norway rat)	Kat8	NP_001017378.1
Drosophila melanogaster (fruit fly)	mof	NP_511051.1
Oryza sativa (rice)	Os07g0626600	NP_001060338.1

Gene Ontology
Bibliography

Related articles in PubMed

Revealing the Protein Propionylation Activity of the Histone Acetyltransferase Males absent on the first (MOF).
Han Z, Wu H, Kim S, Yang X, Li Q, Huang H, Cai H, Bartlett MG, Dong A, Zeng H, Brown PJ, Yang X, Arrowsmith CH, Zhao Y, Zheng YG
The Journal of biological chemistry(2018 Jan)

Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin ?1.
Zheng W, Wang R, Liu X, Tian S, Yao B, Chen A, Jin S, Li Y
Traffic (Copenhagen, Denmark)19(1)19-28(2018 Jan)

Histone Acetyltransferase Activity of MOF Is Required for
Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA
Cancer research77(7)1753-1762(2017 Apr)

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.
Chatterjee A, Seyfferth J, Lucci J, Gilsbach R, Preissl S, B?ttinger L, M?rtensson CU, Panhale A, Stehle T, Kretz O, Sahyoun AH, Avilov S, Eimer S, Hein L, Pfanner N, Becker T, Akhtar A
Cell167(3)722-738.e23(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Histone acetyltransferase activity of MOF is required to sustain MLL-AF9 leukemia and may be important for multiple AML subtypes.
Title: Histone Acetyltransferase Activity of MOF Is Required for

our findings reveal that TET1 forms a complex with hMOF to modulate its function and the level of H4K16Ac ultimately affect gene expression and DNA repair.
Title: TET1 modulates H4K16 acetylation by controlling auto-acetylation of hMOF to affect gene regulation and DNA repair function.

MOF is a dual-transcriptional regulator of nuclear and mitochondrial genomes connecting epigenetics and metabolism.
Title: MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.

these studies point to the critical and specific role of hMOF Lys-274 autoacetylation in hMOF stability and cognate substrate acetylation and argues that binding of Ac-CoA to hMOF likely drives Lys-274 autoacetylation for subsequent cognate substrate acetylation.
Title: Structural and Functional Role of Acetyltransferase hMOF K274 Autoacetylation.

These findings provide insight into the regulation of LSD1 and Epithelial-to-Mesenchymal Transition (EMT) and identify MOF as a critical suppressor of EMT and tumor progression.
Title: MOF Acetylates the Histone Demethylase LSD1 to Suppress Epithelial-to-Mesenchymal Transition.

The following KAT8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KAT8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu22782	NM_182958.3 Latest version!	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu23171	NM_032188.3 Latest version!	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu73360	XM_011545970.1 Latest version!	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
OHu73360	XM_011545971.1 Latest version!	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	5-7	$139.30 $199.00
View Old Accession Versions >>
OHu22782	NM_182958.2	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu23171	NM_032188.2	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KAT8 ( NM_182958.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_892003.2 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22782
Clone ID Related Accession (Same CDS sequence)	NM_182958.3 , NM_182958.2
Accession Version	NM_182958.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-04
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC135050.3 and AC009088.9. On May 31, 2019 this sequence version replaced NM_182958.2. Transcript Variant: This variant (2) includes an alternate segment, compared to variant 1, that causes a frameshift. The resulting protein (isoform 2) has a distinct and longer C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225660.1, BC037773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGGTGGGTGG 
GGGGCTGCTG TGTGTCGGGG GCGGTGGGGG AGTGTCAGTA TATGGACTGG TAGGAGTCAA 
GGCCTCCTTA TTGCTGTCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_892003.2
CDS	19..1422
Translation	MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITGGWGAAVCRGRWGSVSIWTGRSQGLLIAVT

Target ORF information:

RefSeq Version	NM_182958.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182958.3

ORF Insert Sequence:

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGGTGGGTGG 
GGGGCTGCTG TGTGTCGGGG GCGGTGGGGG AGTGTCAGTA TATGGACTGG TAGGAGTCAA 
GGCCTCCTTA TTGCTGTCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT8 ( NM_182958.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_892003.2 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu22782
Clone ID Related Accession (Same CDS sequence)	NM_182958.3 , NM_182958.2
Accession Version	NM_182958.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1404bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-19
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK225660.1, AA682878.1, BC037773.1 and CD364543.1. On Apr 4, 2009 this sequence version replaced NM_182958.1. Transcript Variant: This variant (2) includes an alternate segment, compared to variant 1, that causes a frameshift. The resulting protein (isoform 2) has a distinct and longer C-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225660.1, BC037773.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGGTGGGTGG 
GGGGCTGCTG TGTGTCGGGG GCGGTGGGGG AGTGTCAGTA TATGGACTGG TAGGAGTCAA 
GGCCTCCTTA TTGCTGTCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_892003.2
CDS	19..1422
Translation	MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITGGWGAAVCRGRWGSVSIWTGRSQGLLIAVT

Target ORF information:

RefSeq Version	NM_182958.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_182958.2

ORF Insert Sequence:

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGGTGGGTGG 
GGGGCTGCTG TGTGTCGGGG GCGGTGGGGG AGTGTCAGTA TATGGACTGG TAGGAGTCAA 
GGCCTCCTTA TTGCTGTCAC ATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT8 ( NM_032188.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_115564.2 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu23171
Clone ID Related Accession (Same CDS sequence)	NM_032188.3 , NM_032188.2
Accession Version	NM_032188.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP342476.1, AK291106.1, AA682878.1 and CD364543.1. On Nov 24, 2018 this sequence version replaced NM_032188.2. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK291106.1, SRR3476690.842302.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000219797.9/ ENSP00000219797.3 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGTGGACTCC 
GTCTGCCTCA AGTGGGCACC CCCCAAGCAC AAGCAAGTCA AGCTCTCCAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115564.2
CDS	19..1395
Translation	MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

Target ORF information:

RefSeq Version	NM_032188.3
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032188.3

ORF Insert Sequence:

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGTGGACTCC 
GTCTGCCTCA AGTGGGCACC CCCCAAGCAC AAGCAAGTCA AGCTCTCCAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT8 ( NM_032188.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_115564.2 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.

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CloneID	OHu23171
Clone ID Related Accession (Same CDS sequence)	NM_032188.3 , NM_032188.2
Accession Version	NM_032188.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1377bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP342476.1, AK291106.1, AA682878.1 and CD364543.1. On Apr 4, 2009 this sequence version replaced NM_032188.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the shorter isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK024102.1, SRR1163658.83400.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGTGGACTCC 
GTCTGCCTCA AGTGGGCACC CCCCAAGCAC AAGCAAGTCA AGCTCTCCAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_115564.2
CDS	19..1395
Translation	MAAQGAAAAVAAGTSGVAGEGEPGPGENAAAEGTAPSPGRVSPPTPARGEPEVTVEIGETYLCRRPDSTWHSAEVIQSRVNDQEGREEFYVHYVGFNRRLDEWVDKNRLALTKTVKDAVQKNSEKYLSELAEQPERKITRNQKRKHDEINHVQKTYAEMDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

Target ORF information:

RefSeq Version	NM_032188.2
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_032188.2

ORF Insert Sequence:

ATGGCGGCAC AGGGAGCTGC TGCGGCGGTT GCGGCGGGGA CTTCAGGGGT CGCGGGGGAG 
GGCGAGCCCG GGCCCGGGGA GAATGCGGCC GCTGAGGGGA CCGCCCCATC CCCGGGCCGC 
GTCTCTCCGC CGACCCCGGC GCGCGGCGAG CCGGAAGTCA CGGTGGAGAT CGGAGAAACG 
TACCTGTGCC GGCGACCGGA TAGCACCTGG CATTCTGCTG AAGTGATCCA GTCTCGAGTG 
AACGACCAGG AGGGCCGAGA GGAATTCTAT GTACACTACG TGGGCTTTAA CCGGCGGCTG 
GACGAGTGGG TAGACAAGAA CCGGCTGGCG CTGACCAAGA CAGTGAAGGA TGCTGTACAG 
AAGAACTCAG AGAAGTACCT GAGCGAGCTC GCAGAGCAGC CTGAGCGCAA GATCACTCGC 
AACCAAAAGC GCAAGCATGA TGAGATCAAC CATGTGCAGA AGACTTATGC AGAGATGGAC 
CCCACCACAG CAGCCTTGGA GAAGGAGCAT GAGGCGATCA CCAAGGTGAA GTATGTGGAC 
AAGATCCACA TCGGGAACTA CGAAATTGAT GCCTGGTATT TCTCACCATT CCCCGAAGAC 
TATGGGAAAC AGCCCAAGCT CTGGCTCTGC GAGTACTGCC TCAAGTACAT GAAATATGAG 
AAGAGCTACC GCTTCCACTT GGGTCAGTGC CAGTGGCGGC AGCCCCCCGG GAAAGAGATC 
TACCGCAAGA GCAACATCTC CGTGTACGAA GTTGATGGCA AAGACCATAA GATTTACTGT 
CAGAACCTGT GTCTGCTGGC CAAGCTTTTC CTGGACCATA AGACACTGTA CTTTGACGTG 
GAGCCGTTCG TCTTTTACAT CCTGACTGAG GTGGACCGGC AGGGGGCCCA CATTGTTGGC 
TACTTCTCCA AGGAGAAGGA GTCCCCGGAT GGAAACAATG TGGCCTGCAT CCTGACCTTG 
CCCCCCTACC AACGCCGCGG CTACGGGAAG TTCCTCATCG CTTTCAGTTA TGAGCTCTCC 
AAGCTGGAGA GCACAGTCGG CTCCCCGGAG AAGCCACTGT CTGACCTGGG CAAGCTCAGC 
TACCGCAGCT ACTGGTCCTG GGTGCTGCTA GAGATCCTGC GGGACTTCCG GGGCACACTG 
TCCATCAAGG ACCTCAGCCA GATGACCAGT ATCACCCAAA ATGACATCAT CAGTACCCTG 
CAATCCCTCA ATATGGTCAA GTACTGGAAG GGCCAGCACG TGATCTGTGT CACACCCAAG 
CTGGTGGAGG AGCACCTCAA AAGTGCCCAG TATAAGAAAC CACCCATCAC AGTGGACTCC 
GTCTGCCTCA AGTGGGCACC CCCCAAGCAC AAGCAAGTCA AGCTCTCCAA GAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT8 ( XM_011545971.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544273.1 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X2, mRNA.

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CloneID	OHu73360
Clone ID Related Accession (Same CDS sequence)	XM_011545971.1 , XM_011545970.1
Accession Version	XM_011545971.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCCA CCACAGCAGC CTTGGAGAAG GAGCATGAGG CGATCACCAA GGTGAAGTAT 
GTGGACAAGA TCCACATCGG GAACTACGAA ATTGATGCCT GGTATTTCTC ACCATTCCCC 
GAAGACTATG GGAAACAGCC CAAGCTCTGG CTCTGCGAGT ACTGCCTCAA GTACATGAAA 
TATGAGAAGA GCTACCGCTT CCACTTGGGT CAGTGCCAGT GGCGGCAGCC CCCCGGGAAA 
GAGATCTACC GCAAGAGCAA CATCTCCGTG TACGAAGTTG ATGGCAAAGA CCATAAGATT 
TACTGTCAGA ACCTGTGTCT GCTGGCCAAG CTTTTCCTGG ACCATAAGAC ACTGTACTTT 
GACGTGGAGC CGTTCGTCTT TTACATCCTG ACTGAGGTGG ACCGGCAGGG GGCCCACATT 
GTTGGCTACT TCTCCAAGGA GAAGGAGTCC CCGGATGGAA ACAATGTGGC CTGCATCCTG 
ACCTTGCCCC CCTACCAACG CCGCGGCTAC GGGAAGTTCC TCATCGCTTT CAGTTATGAG 
CTCTCCAAGC TGGAGAGCAC AGTCGGCTCC CCGGAGAAGC CACTGTCTGA CCTGGGCAAG 
CTCAGCTACC GCAGCTACTG GTCCTGGGTG CTGCTAGAGA TCCTGCGGGA CTTCCGGGGC 
ACACTGTCCA TCAAGGACCT CAGCCAGATG ACCAGTATCA CCCAAAATGA CATCATCAGT 
ACCCTGCAAT CCCTCAATAT GGTCAAGTAC TGGAAGGGCC AGCACGTGAT CTGTGTCACA 
CCCAAGCTGG TGGAGGAGCA CCTCAAAAGT GCCCAGTATA AGAAACCACC CATCACAGTG 
GACTCCGTCT GCCTCAAGTG GGCACCCCCC AAGCACAAGC AAGTCAAGCT CTCCAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544273.1
CDS	1039..1941
Translation	MDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

Target ORF information:

RefSeq Version	XM_011545971.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545971.1

ORF Insert Sequence:

ATGGACCCCA CCACAGCAGC CTTGGAGAAG GAGCATGAGG CGATCACCAA GGTGAAGTAT 
GTGGACAAGA TCCACATCGG GAACTACGAA ATTGATGCCT GGTATTTCTC ACCATTCCCC 
GAAGACTATG GGAAACAGCC CAAGCTCTGG CTCTGCGAGT ACTGCCTCAA GTACATGAAA 
TATGAGAAGA GCTACCGCTT CCACTTGGGT CAGTGCCAGT GGCGGCAGCC CCCCGGGAAA 
GAGATCTACC GCAAGAGCAA CATCTCCGTG TACGAAGTTG ATGGCAAAGA CCATAAGATT 
TACTGTCAGA ACCTGTGTCT GCTGGCCAAG CTTTTCCTGG ACCATAAGAC ACTGTACTTT 
GACGTGGAGC CGTTCGTCTT TTACATCCTG ACTGAGGTGG ACCGGCAGGG GGCCCACATT 
GTTGGCTACT TCTCCAAGGA GAAGGAGTCC CCGGATGGAA ACAATGTGGC CTGCATCCTG 
ACCTTGCCCC CCTACCAACG CCGCGGCTAC GGGAAGTTCC TCATCGCTTT CAGTTATGAG 
CTCTCCAAGC TGGAGAGCAC AGTCGGCTCC CCGGAGAAGC CACTGTCTGA CCTGGGCAAG 
CTCAGCTACC GCAGCTACTG GTCCTGGGTG CTGCTAGAGA TCCTGCGGGA CTTCCGGGGC 
ACACTGTCCA TCAAGGACCT CAGCCAGATG ACCAGTATCA CCCAAAATGA CATCATCAGT 
ACCCTGCAAT CCCTCAATAT GGTCAAGTAC TGGAAGGGCC AGCACGTGAT CTGTGTCACA 
CCCAAGCTGG TGGAGGAGCA CCTCAAAAGT GCCCAGTATA AGAAACCACC CATCACAGTG 
GACTCCGTCT GCCTCAAGTG GGCACCCCCC AAGCACAAGC AAGTCAAGCT CTCCAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

KAT8 ( XM_011545970.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011544272.1 Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu73360
Clone ID Related Accession (Same CDS sequence)	XM_011545971.1 , XM_011545970.1
Accession Version	XM_011545970.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	histone acetyltransferase KAT8 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000016.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGACCCCA CCACAGCAGC CTTGGAGAAG GAGCATGAGG CGATCACCAA GGTGAAGTAT 
GTGGACAAGA TCCACATCGG GAACTACGAA ATTGATGCCT GGTATTTCTC ACCATTCCCC 
GAAGACTATG GGAAACAGCC CAAGCTCTGG CTCTGCGAGT ACTGCCTCAA GTACATGAAA 
TATGAGAAGA GCTACCGCTT CCACTTGGGT CAGTGCCAGT GGCGGCAGCC CCCCGGGAAA 
GAGATCTACC GCAAGAGCAA CATCTCCGTG TACGAAGTTG ATGGCAAAGA CCATAAGATT 
TACTGTCAGA ACCTGTGTCT GCTGGCCAAG CTTTTCCTGG ACCATAAGAC ACTGTACTTT 
GACGTGGAGC CGTTCGTCTT TTACATCCTG ACTGAGGTGG ACCGGCAGGG GGCCCACATT 
GTTGGCTACT TCTCCAAGGA GAAGGAGTCC CCGGATGGAA ACAATGTGGC CTGCATCCTG 
ACCTTGCCCC CCTACCAACG CCGCGGCTAC GGGAAGTTCC TCATCGCTTT CAGTTATGAG 
CTCTCCAAGC TGGAGAGCAC AGTCGGCTCC CCGGAGAAGC CACTGTCTGA CCTGGGCAAG 
CTCAGCTACC GCAGCTACTG GTCCTGGGTG CTGCTAGAGA TCCTGCGGGA CTTCCGGGGC 
ACACTGTCCA TCAAGGACCT CAGCCAGATG ACCAGTATCA CCCAAAATGA CATCATCAGT 
ACCCTGCAAT CCCTCAATAT GGTCAAGTAC TGGAAGGGCC AGCACGTGAT CTGTGTCACA 
CCCAAGCTGG TGGAGGAGCA CCTCAAAAGT GCCCAGTATA AGAAACCACC CATCACAGTG 
GACTCCGTCT GCCTCAAGTG GGCACCCCCC AAGCACAAGC AAGTCAAGCT CTCCAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011544272.1
CDS	1034..1936
Translation	MDPTTAALEKEHEAITKVKYVDKIHIGNYEIDAWYFSPFPEDYGKQPKLWLCEYCLKYMKYEKSYRFHLGQCQWRQPPGKEIYRKSNISVYEVDGKDHKIYCQNLCLLAKLFLDHKTLYFDVEPFVFYILTEVDRQGAHIVGYFSKEKESPDGNNVACILTLPPYQRRGYGKFLIAFSYELSKLESTVGSPEKPLSDLGKLSYRSYWSWVLLEILRDFRGTLSIKDLSQMTSITQNDIISTLQSLNMVKYWKGQHVICVTPKLVEEHLKSAQYKKPPITVDSVCLKWAPPKHKQVKLSKK

Target ORF information:

RefSeq Version	XM_011545970.1
Organism	Homo sapiens(human)
Definition	Homo sapiens lysine acetyltransferase 8 (KAT8), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011545970.1

ORF Insert Sequence:

ATGGACCCCA CCACAGCAGC CTTGGAGAAG GAGCATGAGG CGATCACCAA GGTGAAGTAT 
GTGGACAAGA TCCACATCGG GAACTACGAA ATTGATGCCT GGTATTTCTC ACCATTCCCC 
GAAGACTATG GGAAACAGCC CAAGCTCTGG CTCTGCGAGT ACTGCCTCAA GTACATGAAA 
TATGAGAAGA GCTACCGCTT CCACTTGGGT CAGTGCCAGT GGCGGCAGCC CCCCGGGAAA 
GAGATCTACC GCAAGAGCAA CATCTCCGTG TACGAAGTTG ATGGCAAAGA CCATAAGATT 
TACTGTCAGA ACCTGTGTCT GCTGGCCAAG CTTTTCCTGG ACCATAAGAC ACTGTACTTT 
GACGTGGAGC CGTTCGTCTT TTACATCCTG ACTGAGGTGG ACCGGCAGGG GGCCCACATT 
GTTGGCTACT TCTCCAAGGA GAAGGAGTCC CCGGATGGAA ACAATGTGGC CTGCATCCTG 
ACCTTGCCCC CCTACCAACG CCGCGGCTAC GGGAAGTTCC TCATCGCTTT CAGTTATGAG 
CTCTCCAAGC TGGAGAGCAC AGTCGGCTCC CCGGAGAAGC CACTGTCTGA CCTGGGCAAG 
CTCAGCTACC GCAGCTACTG GTCCTGGGTG CTGCTAGAGA TCCTGCGGGA CTTCCGGGGC 
ACACTGTCCA TCAAGGACCT CAGCCAGATG ACCAGTATCA CCCAAAATGA CATCATCAGT 
ACCCTGCAAT CCCTCAATAT GGTCAAGTAC TGGAAGGGCC AGCACGTGAT CTGTGTCACA 
CCCAAGCTGG TGGAGGAGCA CCTCAAAAGT GCCCAGTATA AGAAACCACC CATCACAGTG 
GACTCCGTCT GCCTCAAGTG GGCACCCCCC AAGCACAAGC AAGTCAAGCT CTCCAAGAAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Revealing the Protein Propionylation Activity of the Histone Acetyltransferase Males absent on the first (MOF).
The Journal of biological chemistry(2018 Jan)
Han Z,Wu H,Kim S,Yang X,Li Q,Huang H,Cai H,Bartlett MG,Dong A,Zeng H,Brown PJ,Yang X,Arrowsmith CH,Zhao Y,Zheng YG

Structural insights into the nuclear import of the histone acetyltransferase males-absent-on-the-first by importin ?1.
Traffic (Copenhagen, Denmark)19(1)19-28(2018 Jan)
Zheng W,Wang R,Liu X,Tian S,Yao B,Chen A,Jin S,Li Y

Histone Acetyltransferase Activity of MOF Is Required for
Cancer research77(7)1753-1762(2017 Apr)
Valerio DG,Xu H,Chen CW,Hoshii T,Eisold ME,Delaney C,Cusan M,Deshpande AJ,Huang CH,Lujambio A,Zheng YG,Zuber J,Pandita TK,Lowe SW,Armstrong SA

MOF Acetyl Transferase Regulates Transcription and Respiration in Mitochondria.
Cell167(3)722-738.e23(2016 Oct)
Chatterjee A,Seyfferth J,Lucci J,Gilsbach R,Preissl S,B?ttinger L,M?rtensson CU,Panhale A,Stehle T,Kretz O,Sahyoun AH,Avilov S,Eimer S,Hein L,Pfanner N,Becker T,Akhtar A

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KAT8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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