TMPRSS13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMPRSS13
Entrez Gene ID	84000
Full Name	transmembrane serine protease 13
Synonyms	MSP,MSPL,MSPS,TMPRSS11
General protein information	Preferred Names transmembrane serine protease 13 Names transmembrane protease serine 13 membrane-type mosaic serine protease transmembrane protease, serine 11 transmembrane protease, serine 13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11q23.3
Summary	This gene encodes a member of the type II transmembrane serine protease family. Transmembrane serine proteases are regulated by protease inhibitors and known to function in development, homeostasis, infection, and tumorigenesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].
Disorder MIM:	610050

mRNA and Protein(s)

mRNA	Protein	Name
NM_001077263.2	NP_001070731.1	transmembrane protease serine 13 isoform 1
NM_001244995.1	NP_001231924.1	transmembrane protease serine 13 isoform 4
NM_001077263.3	NP_001070731.1	transmembrane protease serine 13 isoform 1
NM_001206789.1	NP_001193718.1	transmembrane protease serine 13 isoform 2
NM_001206790.1	NP_001193719.1	transmembrane protease serine 13 isoform 3
NM_001244995.2	NP_001231924.1	transmembrane protease serine 13 isoform 4
NM_001206789.2	NP_001193718.1	transmembrane protease serine 13 isoform 2

Pathways from BioSystems

Homologies

	TMPRSS13	XP_001096187.2
Bos taurus (cattle)	TMPRSS13	XP_002693049.1
Mus musculus (house mouse)	Tmprss13	NP_001013391.2
Gallus gallus (chicken)	LOC100859131	XP_003642661.2
Rattus norvegicus (Norway rat)	Tmprss13	NP_001121000.1
Danio rerio (zebrafish)	tmprss13b	NP_001076313.1
Pan troglodytes (chimpanzee)	TMPRSS13	XP_001159065.2
Homo sapiens (human)	TMPRSS13	NP_001070731.1
Danio rerio (zebrafish)	tmprss13a	NP_001152984.1
Xenopus tropicalis (tropical clawed frog)	tmprss13	XP_002932950.2
Canis lupus familiaris (dog)	TMPRSS13	XP_005619777.1

Gene Ontology
Bibliography

Related articles in PubMed

Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.
Murray AS, Varela FA, Hyland TE, Schoenbeck AJ, White JM, Tanabe LM, Todi SV, List K
The Journal of biological chemistry292(36)14867-14884(2017 09)

DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Zmora P, Blazejewska P, Moldenhauer AS, Welsch K, Nehlmeier I, Wu Q, Schneider H, P?hlmann S, Bertram S
Journal of virology88(20)12087-97(2014 Oct)

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
Bastos-Amador P, Royo F, Gonzalez E, Conde-Vancells J, Palomo-Diez L, Borras FE, Falcon-Perez JM
Journal of proteomics75(12)3574-84(2012 Jun)

TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.
Hashimoto T, Kato M, Shimomura T, Kitamura N
The FEBS journal277(23)4888-900(2010 Dec)

Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.
Okumura Y, Takahashi E, Yano M, Ohuchi M, Daidoji T, Nakaya T, B?ttcher E, Garten W, Klenk HD, Kido H
Journal of virology84(10)5089-96(2010 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The data provide novel insight into the cellular properties of TMPRSS13 and highlight phosphorylation of TMPRSS13 as a novel post-translational modification of this TTSP family member and potentially other members of this family of proteases.
Title: Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.

study demonstrates that two cellular serine proteases, DESC1 and MSPL, activate influenza viruses and emerging coronaviruses in cell culture and, because of their expression in human lung tissue, might promote viral spread in the infected host
Title: DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.

results suggest that TMPRSS13 functions as an HGF-converting protease, the activity of which may be regulated by HAI-1
Title: TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.

The authors report that serine proteases, MSPL and its splice variant TMPRSS13, are novel candidates for proteases processing HA proteins of highly pathogenic avian influenza (HPAI) viruses.
Title: Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.

cloning of MSPL/TMPRSS13, which may play roles in the proteolytic processing of prohormones, precursors of growth factors, and also play roles in the pathogenicity of many viruses and bacteria in vivo
Title: MSPL/TMPRSS13.

The following TMPRSS13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMPRSS13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu21343	NM_001077263.3 Latest version!	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$239.50-$335.30 $479.00
OHu00167	NM_001206789.2 Latest version!	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu21478	NM_001206790.1 Latest version!	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu21840	NM_001244995.2 Latest version!	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
View Old Accession Versions >>
OHu21343	NM_001077263.2	Homo sapiens transmembrane protease, serine 13 (TMPRSS13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$239.50-$335.30 $479.00
OHu21840	NM_001244995.1	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
OHu00167	NM_001206789.1	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$307.30 $439.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMPRSS13 ( NM_001077263.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070731.1 Homo sapiens transmembrane protease, serine 13 (TMPRSS13), transcript variant 1, mRNA.

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CloneID	OHu21343
Clone ID Related Accession (Same CDS sequence)	NM_001077263.2 , NM_001077263.3
Accession Version	NM_001077263.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002962.2, BC114928.1 and AW014913.1. This sequence is a reference standard in the RefSeqGene project. On May 5, 2011 this sequence version replaced NM_001077263.1. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC114928.1, AK300283.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
GAGGTGCGAT TCAGAAAATC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070731.1
CDS	147..1850
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS

Target ORF information:

RefSeq Version	NM_001077263.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protease, serine 13 (TMPRSS13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077263.2

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
GAGGTGCGAT TCAGAAAATC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001077263.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001070731.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu21343
Clone ID Related Accession (Same CDS sequence)	NM_001077263.2 , NM_001077263.3
Accession Version	NM_001077263.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1704bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-23
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002962.2, BC114928.1 and AW014913.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_001077263.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: BC114928.1, AK300283.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000524993.6/ ENSP00000434279.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
GAGGTGCGAT TCAGAAAATC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070731.1
CDS	96..1799
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS

Target ORF information:

RefSeq Version	NM_001077263.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001077263.3

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
GAGGTGCGAT TCAGAAAATC CTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001206789.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193718.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu00167
Clone ID Related Accession (Same CDS sequence)	NM_001206789.1 , NM_001206789.2
Accession Version	NM_001206789.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-21
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002962.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AB048797.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GTCCAGTTCT GGCAGGGCCA CACAGGGATC 
AGGTACAAGG AGCAGAGGGA GAGCTGTCCC AAGCACGCTG TTCGCTGTGA CGGGGTGGTG 
GACTGCAAGC TGAAGAGTGA CGAGCTGGGC TGCGTGAGGT TTGACTGGGA CAAGTCTCTG 
CTTAAAATCT ACTCTGGGTC CTCCCATCAG TGGCTTCCCA TCTGTAGCAG CAACTGGAAT 
GACTCCTACT CAGAGAAGAC CTGCCAGCAG CTGGGTTTCG AGAGTGCTCA CCGGACAACC 
GAGGTTGCCC ACAGGGATTT TGCCAACAGC TTCTCAATCT TGAGATACAA CTCCACCATC 
CAGGAAAGCC TCCACAGGTC TGAATGCCCT TCCCAGCGGT ATATCTCTCT CCAGTGTTCC 
CACTGCGGAC TGAGGGCCAT GACCGGGCGG ATCGTGGGAG GGGCGCTGGC CTCGGATAGC 
AAGTGGCCTT GGCAAGTGAG TCTGCACTTC GGCACCACCC ACATCTGTGG AGGCACGCTC 
ATTGACGCCC AGTGGGTGCT CACTGCCGCC CACTGCTTCT TCGTGACCCG GGAGAAGGTC 
CTGGAGGGCT GGAAGGTGTA CGCGGGCACC AGCAACCTGC ACCAGTTGCC TGAGGCAGCC 
TCCATTGCCG AGATCATCAT CAACAGCAAT TACACCGATG AGGAGGACGA CTATGACATC 
GCCCTCATGC GGCTGTCCAA GCCCCTGACC CTGTCCGCTC ACATCCACCC TGCTTGCCTC 
CCCATGCATG GACAGACCTT TAGCCTCAAT GAGACCTGCT GGATCACAGG CTTTGGCAAG 
ACCAGGGAGA CAGATGACAA GACATCCCCC TTCCTCCGGG AGGTGCAGGT CAATCTCATC 
GACTTCAAGA AATGCAATGA CTACTTGGTC TATGACAGTT ACCTTACCCC AAGGATGATG 
TGTGCTGGGG ACCTTCGTGG GGGCAGAGAC TCCTGCCAGG GAGACAGCGG GGGGCCTCTT 
GTCTGTGAGC AGAACAACCG CTGGTACCTG GCAGGTGTCA CCAGCTGGGG CACAGGCTGT 
GGCCAGAGAA ACAAACCTGG TGTGTACACC AAAGTGACAG AAGTTCTTCC CTGGATTTAC 
AGCAAGATGG AGAGCGAGGT GCGATTCAGA AAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193718.1
CDS	147..1745
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPVQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS

Target ORF information:

RefSeq Version	NM_001206789.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206789.1

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GTCCAGTTCT GGCAGGGCCA CACAGGGATC 
AGGTACAAGG AGCAGAGGGA GAGCTGTCCC AAGCACGCTG TTCGCTGTGA CGGGGTGGTG 
GACTGCAAGC TGAAGAGTGA CGAGCTGGGC TGCGTGAGGT TTGACTGGGA CAAGTCTCTG 
CTTAAAATCT ACTCTGGGTC CTCCCATCAG TGGCTTCCCA TCTGTAGCAG CAACTGGAAT 
GACTCCTACT CAGAGAAGAC CTGCCAGCAG CTGGGTTTCG AGAGTGCTCA CCGGACAACC 
GAGGTTGCCC ACAGGGATTT TGCCAACAGC TTCTCAATCT TGAGATACAA CTCCACCATC 
CAGGAAAGCC TCCACAGGTC TGAATGCCCT TCCCAGCGGT ATATCTCTCT CCAGTGTTCC 
CACTGCGGAC TGAGGGCCAT GACCGGGCGG ATCGTGGGAG GGGCGCTGGC CTCGGATAGC 
AAGTGGCCTT GGCAAGTGAG TCTGCACTTC GGCACCACCC ACATCTGTGG AGGCACGCTC 
ATTGACGCCC AGTGGGTGCT CACTGCCGCC CACTGCTTCT TCGTGACCCG GGAGAAGGTC 
CTGGAGGGCT GGAAGGTGTA CGCGGGCACC AGCAACCTGC ACCAGTTGCC TGAGGCAGCC 
TCCATTGCCG AGATCATCAT CAACAGCAAT TACACCGATG AGGAGGACGA CTATGACATC 
GCCCTCATGC GGCTGTCCAA GCCCCTGACC CTGTCCGCTC ACATCCACCC TGCTTGCCTC 
CCCATGCATG GACAGACCTT TAGCCTCAAT GAGACCTGCT GGATCACAGG CTTTGGCAAG 
ACCAGGGAGA CAGATGACAA GACATCCCCC TTCCTCCGGG AGGTGCAGGT CAATCTCATC 
GACTTCAAGA AATGCAATGA CTACTTGGTC TATGACAGTT ACCTTACCCC AAGGATGATG 
TGTGCTGGGG ACCTTCGTGG GGGCAGAGAC TCCTGCCAGG GAGACAGCGG GGGGCCTCTT 
GTCTGTGAGC AGAACAACCG CTGGTACCTG GCAGGTGTCA CCAGCTGGGG CACAGGCTGT 
GGCCAGAGAA ACAAACCTGG TGTGTACACC AAAGTGACAG AAGTTCTTCC CTGGATTTAC 
AGCAAGATGG AGAGCGAGGT GCGATTCAGA AAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001206789.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193718.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.

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CloneID	OHu00167
Clone ID Related Accession (Same CDS sequence)	NM_001206789.1 , NM_001206789.2
Accession Version	NM_001206789.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1599bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002962.2. On May 31, 2019 this sequence version replaced NM_001206789.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region compared to variant 1. The resulting protein (isoform 2) is shorter compared to isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AB048797.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GTCCAGTTCT GGCAGGGCCA CACAGGGATC 
AGGTACAAGG AGCAGAGGGA GAGCTGTCCC AAGCACGCTG TTCGCTGTGA CGGGGTGGTG 
GACTGCAAGC TGAAGAGTGA CGAGCTGGGC TGCGTGAGGT TTGACTGGGA CAAGTCTCTG 
CTTAAAATCT ACTCTGGGTC CTCCCATCAG TGGCTTCCCA TCTGTAGCAG CAACTGGAAT 
GACTCCTACT CAGAGAAGAC CTGCCAGCAG CTGGGTTTCG AGAGTGCTCA CCGGACAACC 
GAGGTTGCCC ACAGGGATTT TGCCAACAGC TTCTCAATCT TGAGATACAA CTCCACCATC 
CAGGAAAGCC TCCACAGGTC TGAATGCCCT TCCCAGCGGT ATATCTCTCT CCAGTGTTCC 
CACTGCGGAC TGAGGGCCAT GACCGGGCGG ATCGTGGGAG GGGCGCTGGC CTCGGATAGC 
AAGTGGCCTT GGCAAGTGAG TCTGCACTTC GGCACCACCC ACATCTGTGG AGGCACGCTC 
ATTGACGCCC AGTGGGTGCT CACTGCCGCC CACTGCTTCT TCGTGACCCG GGAGAAGGTC 
CTGGAGGGCT GGAAGGTGTA CGCGGGCACC AGCAACCTGC ACCAGTTGCC TGAGGCAGCC 
TCCATTGCCG AGATCATCAT CAACAGCAAT TACACCGATG AGGAGGACGA CTATGACATC 
GCCCTCATGC GGCTGTCCAA GCCCCTGACC CTGTCCGCTC ACATCCACCC TGCTTGCCTC 
CCCATGCATG GACAGACCTT TAGCCTCAAT GAGACCTGCT GGATCACAGG CTTTGGCAAG 
ACCAGGGAGA CAGATGACAA GACATCCCCC TTCCTCCGGG AGGTGCAGGT CAATCTCATC 
GACTTCAAGA AATGCAATGA CTACTTGGTC TATGACAGTT ACCTTACCCC AAGGATGATG 
TGTGCTGGGG ACCTTCGTGG GGGCAGAGAC TCCTGCCAGG GAGACAGCGG GGGGCCTCTT 
GTCTGTGAGC AGAACAACCG CTGGTACCTG GCAGGTGTCA CCAGCTGGGG CACAGGCTGT 
GGCCAGAGAA ACAAACCTGG TGTGTACACC AAAGTGACAG AAGTTCTTCC CTGGATTTAC 
AGCAAGATGG AGAGCGAGGT GCGATTCAGA AAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193718.1
CDS	96..1694
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPVQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS

Target ORF information:

RefSeq Version	NM_001206789.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206789.2

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GTCCAGTTCT GGCAGGGCCA CACAGGGATC 
AGGTACAAGG AGCAGAGGGA GAGCTGTCCC AAGCACGCTG TTCGCTGTGA CGGGGTGGTG 
GACTGCAAGC TGAAGAGTGA CGAGCTGGGC TGCGTGAGGT TTGACTGGGA CAAGTCTCTG 
CTTAAAATCT ACTCTGGGTC CTCCCATCAG TGGCTTCCCA TCTGTAGCAG CAACTGGAAT 
GACTCCTACT CAGAGAAGAC CTGCCAGCAG CTGGGTTTCG AGAGTGCTCA CCGGACAACC 
GAGGTTGCCC ACAGGGATTT TGCCAACAGC TTCTCAATCT TGAGATACAA CTCCACCATC 
CAGGAAAGCC TCCACAGGTC TGAATGCCCT TCCCAGCGGT ATATCTCTCT CCAGTGTTCC 
CACTGCGGAC TGAGGGCCAT GACCGGGCGG ATCGTGGGAG GGGCGCTGGC CTCGGATAGC 
AAGTGGCCTT GGCAAGTGAG TCTGCACTTC GGCACCACCC ACATCTGTGG AGGCACGCTC 
ATTGACGCCC AGTGGGTGCT CACTGCCGCC CACTGCTTCT TCGTGACCCG GGAGAAGGTC 
CTGGAGGGCT GGAAGGTGTA CGCGGGCACC AGCAACCTGC ACCAGTTGCC TGAGGCAGCC 
TCCATTGCCG AGATCATCAT CAACAGCAAT TACACCGATG AGGAGGACGA CTATGACATC 
GCCCTCATGC GGCTGTCCAA GCCCCTGACC CTGTCCGCTC ACATCCACCC TGCTTGCCTC 
CCCATGCATG GACAGACCTT TAGCCTCAAT GAGACCTGCT GGATCACAGG CTTTGGCAAG 
ACCAGGGAGA CAGATGACAA GACATCCCCC TTCCTCCGGG AGGTGCAGGT CAATCTCATC 
GACTTCAAGA AATGCAATGA CTACTTGGTC TATGACAGTT ACCTTACCCC AAGGATGATG 
TGTGCTGGGG ACCTTCGTGG GGGCAGAGAC TCCTGCCAGG GAGACAGCGG GGGGCCTCTT 
GTCTGTGAGC AGAACAACCG CTGGTACCTG GCAGGTGTCA CCAGCTGGGG CACAGGCTGT 
GGCCAGAGAA ACAAACCTGG TGTGTACACC AAAGTGACAG AAGTTCTTCC CTGGATTTAC 
AGCAAGATGG AGAGCGAGGT GCGATTCAGA AAATCCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001206790.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001193719.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 3, mRNA.

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CloneID	OHu21478
Clone ID Related Accession (Same CDS sequence)	NM_001206790.1
Accession Version	NM_001206790.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-23
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP002962.2. Transcript Variant: This variant (3) differs in the 3' UTR and coding region compared to variant 1. The resulting protein (isoform 3) has a distinct C-terminus and is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK027798.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGGTGAGGGA ATCTGCACTC CCCGCTCTCC TGCCCCCCAG 
CCCCAGCACC CTCTGCAGCC CTCGCACTTG TCAGCATCTG TCAACTCATA TCCGGGCCCC 
AAAGCTTCTG CAGGGCAGAA GTCAAAGACT CTTAAAGATC CTTACATGGA ACACTTCTGT 
TTTATAATTA GGGAAACTGA AGCCCAAGGG TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001193719.1
CDS	147..1622
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSGEGICTPRSPAPQPQHPLQPSHLSASVNSYPGPKASAGQKSKTLKDPYMEHFCFIIRETEAQGL

Target ORF information:

RefSeq Version	NM_001206790.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001206790.1

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGGTGAGGGA ATCTGCACTC CCCGCTCTCC TGCCCCCCAG 
CCCCAGCACC CTCTGCAGCC CTCGCACTTG TCAGCATCTG TCAACTCATA TCCGGGCCCC 
AAAGCTTCTG CAGGGCAGAA GTCAAAGACT CTTAAAGATC CTTACATGGA ACACTTCTGT 
TTTATAATTA GGGAAACTGA AGCCCAAGGG TTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001244995.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231924.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.

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CloneID	OHu21840
Clone ID Related Accession (Same CDS sequence)	NM_001244995.1 , NM_001244995.2
Accession Version	NM_001244995.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC381405.1, AP002962.2, AY190317.1 and AK027798.1. Transcript Variant: This variant (4) includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY190317.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
TCAGCGGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231924.1
CDS	147..1838
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESSAG

Target ORF information:

RefSeq Version	NM_001244995.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244995.1

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
TCAGCGGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMPRSS13 ( NM_001244995.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001231924.1 Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.

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CloneID	OHu21840
Clone ID Related Accession (Same CDS sequence)	NM_001244995.1 , NM_001244995.2
Accession Version	NM_001244995.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	transmembrane protease serine 13 isoform 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC381405.1, AP002962.2, AY190317.1 and AK027798.1. On May 31, 2019 this sequence version replaced NM_001244995.1. Transcript Variant: This variant (4) includes an alternate 3' terminal exon, compared to variant 1. It encodes isoform 4 which is shorter and has a distinct C-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AY190317.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
TCAGCGGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001231924.1
CDS	96..1787
Translation	MERDSHGNASPARTPSAGASPAQASPAGTPPGRASPAQASPAQASPAGTPPGRASPAQASPAGTPPGRASPGRASPAQASPAQASPARASPALASLSRSSSGRSSSARSASVTTSPTRVYLVRATPVGAVPIRSSPARSAPATRATRESPGTSLPKFTWREGQKQLPLIGCVLLLIALVVSLIILFQFWQGHTGIRYKEQRESCPKHAVRCDGVVDCKLKSDELGCVRFDWDKSLLKIYSGSSHQWLPICSSNWNDSYSEKTCQQLGFESAHRTTEVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDSKWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAASIAEIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESSAG

Target ORF information:

RefSeq Version	NM_001244995.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane serine protease 13 (TMPRSS13), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001244995.2

ORF Insert Sequence:

ATGGAGAGGG ACAGCCACGG GAATGCATCT CCAGCAAGAA CACCTTCAGC TGGAGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC TGGGACACCT CCGGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCTGGTA CACCTCCAGG CCGGGCATCT CCAGGCCGGG CATCTCCAGC CCAGGCATCT 
CCAGCCCAGG CATCTCCAGC CCGGGCATCT CCGGCTCTGG CATCACTTTC CAGGTCCTCA 
TCCGGCAGGT CATCATCCGC CAGGTCAGCC TCGGTGACAA CCTCCCCAAC CAGAGTGTAC 
CTTGTTAGAG CAACACCAGT GGGGGCTGTA CCCATCCGAT CATCTCCTGC CAGGTCAGCA 
CCAGCAACCA GGGCCACCAG GGAGAGCCCA GGTACGAGCC TGCCCAAGTT CACCTGGCGG 
GAGGGCCAGA AGCAGCTACC GCTCATCGGG TGCGTGCTCC TCCTCATTGC CCTGGTGGTT 
TCGCTCATCA TCCTCTTCCA GTTCTGGCAG GGCCACACAG GGATCAGGTA CAAGGAGCAG 
AGGGAGAGCT GTCCCAAGCA CGCTGTTCGC TGTGACGGGG TGGTGGACTG CAAGCTGAAG 
AGTGACGAGC TGGGCTGCGT GAGGTTTGAC TGGGACAAGT CTCTGCTTAA AATCTACTCT 
GGGTCCTCCC ATCAGTGGCT TCCCATCTGT AGCAGCAACT GGAATGACTC CTACTCAGAG 
AAGACCTGCC AGCAGCTGGG TTTCGAGAGT GCTCACCGGA CAACCGAGGT TGCCCACAGG 
GATTTTGCCA ACAGCTTCTC AATCTTGAGA TACAACTCCA CCATCCAGGA AAGCCTCCAC 
AGGTCTGAAT GCCCTTCCCA GCGGTATATC TCTCTCCAGT GTTCCCACTG CGGACTGAGG 
GCCATGACCG GGCGGATCGT GGGAGGGGCG CTGGCCTCGG ATAGCAAGTG GCCTTGGCAA 
GTGAGTCTGC ACTTCGGCAC CACCCACATC TGTGGAGGCA CGCTCATTGA CGCCCAGTGG 
GTGCTCACTG CCGCCCACTG CTTCTTCGTG ACCCGGGAGA AGGTCCTGGA GGGCTGGAAG 
GTGTACGCGG GCACCAGCAA CCTGCACCAG TTGCCTGAGG CAGCCTCCAT TGCCGAGATC 
ATCATCAACA GCAATTACAC CGATGAGGAG GACGACTATG ACATCGCCCT CATGCGGCTG 
TCCAAGCCCC TGACCCTGTC CGCTCACATC CACCCTGCTT GCCTCCCCAT GCATGGACAG 
ACCTTTAGCC TCAATGAGAC CTGCTGGATC ACAGGCTTTG GCAAGACCAG GGAGACAGAT 
GACAAGACAT CCCCCTTCCT CCGGGAGGTG CAGGTCAATC TCATCGACTT CAAGAAATGC 
AATGACTACT TGGTCTATGA CAGTTACCTT ACCCCAAGGA TGATGTGTGC TGGGGACCTT 
CGTGGGGGCA GAGACTCCTG CCAGGGAGAC AGCGGGGGGC CTCTTGTCTG TGAGCAGAAC 
AACCGCTGGT ACCTGGCAGG TGTCACCAGC TGGGGCACAG GCTGTGGCCA GAGAAACAAA 
CCTGGTGTGT ACACCAAAGT GACAGAAGTT CTTCCCTGGA TTTACAGCAA GATGGAGAGC 
TCAGCGGGTT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Phosphorylation of the type II transmembrane serine protease, TMPRSS13, in hepatocyte growth factor activator inhibitor-1 and -2-mediated cell-surface localization.
The Journal of biological chemistry292(36)14867-14884(2017 09)
Murray AS,Varela FA,Hyland TE,Schoenbeck AJ,White JM,Tanabe LM,Todi SV,List K

DESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.
Journal of virology88(20)12087-97(2014 Oct)
Zmora P,Blazejewska P,Moldenhauer AS,Welsch K,Nehlmeier I,Wu Q,Schneider H,P?hlmann S,Bertram S

Proteomic analysis of microvesicles from plasma of healthy donors reveals high individual variability.
Journal of proteomics75(12)3574-84(2012 Jun)
Bastos-Amador P,Royo F,Gonzalez E,Conde-Vancells J,Palomo-Diez L,Borras FE,Falcon-Perez JM

TMPRSS13, a type II transmembrane serine protease, is inhibited by hepatocyte growth factor activator inhibitor type 1 and activates pro-hepatocyte growth factor.
The FEBS journal277(23)4888-900(2010 Dec)
Hashimoto T,Kato M,Shimomura T,Kitamura N

Novel type II transmembrane serine proteases, MSPL and TMPRSS13, Proteolytically activate membrane fusion activity of the hemagglutinin of highly pathogenic avian influenza viruses and induce their multicycle replication.
Journal of virology84(10)5089-96(2010 May)
Okumura Y,Takahashi E,Yano M,Ohuchi M,Daidoji T,Nakaya T,B?ttcher E,Garten W,Klenk HD,Kido H

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TMPRSS13 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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