RILP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RILP
Entrez Gene ID	83547
Full Name	Rab interacting lysosomal protein
Synonyms	PP10141
General protein information	Preferred Names Rab interacting lysosomal protein Names rab-interacting lysosomal protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.3
Summary	This gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology. [provided by RefSeq, Sep 2011].
Disorder MIM:	607848

mRNA and Protein(s)

mRNA	Protein	Name
NM_031430.2	NP_113618.2	rab-interacting lysosomal protein
NM_031430.3	NP_113618.2	rab-interacting lysosomal protein
XM_017025195.1	XP_016880684.1	rab-interacting lysosomal protein isoform X2
XM_005256811.1	XP_005256868.1	rab-interacting lysosomal protein isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	RILP	XP_002695729.1
Mus musculus (house mouse)	Rilp	NP_001025109.1
Homo sapiens (human)	RILP	NP_113618.2
Rattus norvegicus (Norway rat)	Rilp	NP_001099281.1
Pan troglodytes (chimpanzee)	RILP	XP_001174182.2
	RILP	XP_001086142.1
Canis lupus familiaris (dog)	RILP	XP_537768.2

Gene Ontology
Bibliography

Related articles in PubMed

Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP.
Wozniak AL, Long A, Jones-Jamtgaard KN, Weinman SA
Proceedings of the National Academy of Sciences of the United States of America113(44)12484-12489(2016 Nov)

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway.
Song P, Trajkovic K, Tsunemi T, Krainc D
The Journal of neuroscience : the official journal of the Society for Neuroscience36(8)2425-37(2016 Feb)

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

RILP suppresses the invasion of breast cancer cells by interacting with RalGDS to inhibit its guanine nucleotide exchange factor activity for RalA.
Title: RILP suppresses invasion of breast cancer cells by modulating the activity of RalA through interaction with RalGDS.

RILP regulates vacuolar ATPase through interaction with the V1G1 subunit
Title: RILP regulates vacuolar ATPase through interaction with the V1G1 subunit.

VPS41 subunit of HOPS complex was defined to be the major partner for interacting with RILP.
Title: RILP interacts with HOPS complex via VPS41 subunit to regulate endocytic trafficking.

RILP regulates the activity of the V-ATPase through its interaction with V1G1.
Title: RILP regulates vacuolar ATPase through interaction with the V1G1 subunit.

RILP directly and concomitantly binds the tethering HOPS complex and the p150(Glued) subunit of the dynein motor. ORP1L then functions as a cholesterol-sensing switch controlling RILP-HOPS-p150(Glued) interactions.
Title: Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.

The following RILP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RILP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26706	NM_031430.3 Latest version!	Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu49950	XM_005256811.1 Latest version!	Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$223.30 $319.00
OHu87552	XM_017025195.1 Latest version!	Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$139.30 $199.00
View Old Accession Versions >>
OHu26706	NM_031430.2	Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RILP ( NM_031430.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_113618.2 Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.

Price & Availability↑

CloneID	OHu26706
Clone ID Related Accession (Same CDS sequence)	NM_031430.2 , NM_031430.3
Accession Version	NM_031430.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	rab-interacting lysosomal protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ278711.1 and BC004961.1. This sequence is a reference standard in the RefSeqGene project. On Apr 22, 2006 this sequence version replaced NM_031430.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ278711.1, AK055755.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGTGAGGA TGAGGCTGGC 
CCATGGATCC TGCTCTCCGA TGACAAGGGA GACCATCCCC CACCCCCGGA GTCCAAAATA 
CAGAGTTTCT TTGGCCTATG GTATCGGGGT AAAGCTGAAT CCTCTGAGGA TGAGACCAGC 
AGCCCTGCAC CCAGCAAGCT AGGGGGAGAA GAGGAGGCCC AACCACAGTC TCCAGCTCCT 
GATCCGCCCT GTTCTGCCCT CCACGAACAC CTTTGTCTGG GGGCCTCAGC CGCCCCAGAG 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113618.2
CDS	295..1500
Translation	MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA

Target ORF information:

RefSeq Version	NM_031430.2
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031430.2

ORF Insert Sequence:

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGTGAGGA TGAGGCTGGC 
CCATGGATCC TGCTCTCCGA TGACAAGGGA GACCATCCCC CACCCCCGGA GTCCAAAATA 
CAGAGTTTCT TTGGCCTATG GTATCGGGGT AAAGCTGAAT CCTCTGAGGA TGAGACCAGC 
AGCCCTGCAC CCAGCAAGCT AGGGGGAGAA GAGGAGGCCC AACCACAGTC TCCAGCTCCT 
GATCCGCCCT GTTCTGCCCT CCACGAACAC CTTTGTCTGG GGGCCTCAGC CGCCCCAGAG 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RILP ( NM_031430.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_113618.2 Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.

Price & Availability↑

CloneID	OHu26706
Clone ID Related Accession (Same CDS sequence)	NM_031430.2 , NM_031430.3
Accession Version	NM_031430.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	rab-interacting lysosomal protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AJ278711.1 and BC004961.1. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_031430.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ404317.1, BC031621.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000301336.7/ ENSP00000301336.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGTGAGGA TGAGGCTGGC 
CCATGGATCC TGCTCTCCGA TGACAAGGGA GACCATCCCC CACCCCCGGA GTCCAAAATA 
CAGAGTTTCT TTGGCCTATG GTATCGGGGT AAAGCTGAAT CCTCTGAGGA TGAGACCAGC 
AGCCCTGCAC CCAGCAAGCT AGGGGGAGAA GAGGAGGCCC AACCACAGTC TCCAGCTCCT 
GATCCGCCCT GTTCTGCCCT CCACGAACAC CTTTGTCTGG GGGCCTCAGC CGCCCCAGAG 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_113618.2
CDS	63..1268
Translation	MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSEDEAGPWILLSDDKGDHPPPPESKIQSFFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA

Target ORF information:

RefSeq Version	NM_031430.3
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab interacting lysosomal protein (RILP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_031430.3

ORF Insert Sequence:

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGTGAGGA TGAGGCTGGC 
CCATGGATCC TGCTCTCCGA TGACAAGGGA GACCATCCCC CACCCCCGGA GTCCAAAATA 
CAGAGTTTCT TTGGCCTATG GTATCGGGGT AAAGCTGAAT CCTCTGAGGA TGAGACCAGC 
AGCCCTGCAC CCAGCAAGCT AGGGGGAGAA GAGGAGGCCC AACCACAGTC TCCAGCTCCT 
GATCCGCCCT GTTCTGCCCT CCACGAACAC CTTTGTCTGG GGGCCTCAGC CGCCCCAGAG 
GCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RILP ( XM_005256811.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_005256868.1 Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu49950
Clone ID Related Accession (Same CDS sequence)	XM_005256811.1
Accession Version	XM_005256811.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1122bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rab-interacting lysosomal protein isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGCTTTGG CCTATGGTAT 
CGGGGTAAAG CTGAATCCTC TGAGGATGAG ACCAGCAGCC CTGCACCCAG CAAGCTAGGG 
GGAGAAGAGG AGGCCCAACC ACAGTCTCCA GCTCCTGATC CGCCCTGTTC TGCCCTCCAC 
GAACACCTTT GTCTGGGGGC CTCAGCCGCC CCAGAGGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005256868.1
CDS	274..1395
Translation	MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPAEAAQQLGRPSEAGQCRFSREEFEQILQERNELKAKVFLLKEELAYFQRELLTDHRVPGLLLEAMKVAVRKQRKKIKAKMLGTPEEAESSFGLWYRGKAESSEDETSSPAPSKLGGEEEAQPQSPAPDPPCSALHEHLCLGASAAPEA

Target ORF information:

RefSeq Version	XM_005256811.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005256811.1

ORF Insert Sequence:

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGCGGA GGCCGCGCAG CAGCTCGGGC GCCCCTCGGA GGCAGGGCAG 
TGCCGCTTCA GTCGGGAGGA GTTTGAGCAG ATCCTTCAGG AGCGGAATGA ACTCAAAGCC 
AAAGTGTTCC TGCTCAAGGA GGAACTGGCC TACTTCCAGC GGGAGCTGCT CACAGACCAC 
CGGGTCCCCG GCCTTCTGCT CGAGGCCATG AAGGTGGCTG TCCGGAAGCA GCGGAAGAAG 
ATCAAGGCCA AGATGTTAGG GACACCAGAG GAAGCAGAGA GCAGCTTTGG CCTATGGTAT 
CGGGGTAAAG CTGAATCCTC TGAGGATGAG ACCAGCAGCC CTGCACCCAG CAAGCTAGGG 
GGAGAAGAGG AGGCCCAACC ACAGTCTCCA GCTCCTGATC CGCCCTGTTC TGCCCTCCAC 
GAACACCTTT GTCTGGGGGC CTCAGCCGCC CCAGAGGCCT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RILP ( XM_017025195.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016880684.1 Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu87552
Clone ID Related Accession (Same CDS sequence)	XM_017025195.1
Accession Version	XM_017025195.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 822bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	rab-interacting lysosomal protein isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000017.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGGAGC TGCTCACAGA CCACCGGGTC CCCGGCCTTC TGCTCGAGGC 
CATGAAGGTG GCTGTCCGGA AGCAGCGGAA GAAGATCAAG GCCAAGATGT TAGGGACACC 
AGAGGAAGCA GAGAGCAGCT TTGGCCTATG GTATCGGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016880684.1
CDS	274..1095
Translation	MEPRRAAPGVPGWGSREAAGSASAAELVYHLAGALGTELQDLARRFGPEAAAGLVPLVVRALELLEQAAVGPAPDSLQVSAQPAEQELRRLREENERLRRELRAGPQEERALLRQLKEVTDRQRDELRAHNRDLRQRGQETEALQEQLQRLLLVNAELRHKLAAMQTQLRAAQDRERERQQPGEAATPQAKERARGQAGRPGHQHGQEPEWATAGAGAPGNPEDPGAAHRPPGPRPSARGHEGGCPEAAEEDQGQDVRDTRGSREQLWPMVSG

Target ORF information:

RefSeq Version	XM_017025195.1
Organism	Homo sapiens(human)
Definition	Homo sapiens Rab interacting lysosomal protein (RILP), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017025195.1

ORF Insert Sequence:

ATGGAGCCCA GGAGGGCGGC GCCCGGGGTG CCTGGCTGGG GGTCTCGGGA GGCCGCGGGG 
TCGGCATCGG CCGCGGAGCT TGTGTACCAT CTAGCCGGGG CCCTGGGCAC TGAGCTGCAG 
GATCTGGCGC GCCGTTTCGG GCCGGAGGCG GCGGCCGGGC TGGTGCCGCT AGTGGTGCGG 
GCGCTGGAGC TCTTGGAACA GGCTGCCGTG GGGCCCGCCC CGGACTCGCT GCAGGTGTCG 
GCGCAGCCGG CGGAGCAGGA GCTGCGGCGG CTGCGGGAGG AGAACGAGCG CCTCCGCAGG 
GAGCTGCGCG CGGGGCCACA GGAGGAGCGC GCGCTGCTGC GGCAGCTCAA GGAGGTCACG 
GACCGACAGC GGGACGAACT CCGGGCGCAC AACCGCGACC TGCGGCAGCG CGGCCAGGAG 
ACCGAGGCGT TGCAGGAGCA GCTGCAGCGC CTCCTGCTGG TGAACGCTGA GCTGCGGCAC 
AAGCTGGCGG CCATGCAGAC CCAGCTGCGC GCCGCGCAGG ACCGCGAGAG GGAGCGCCAG 
CAGCCTGGCG AAGCCGCGAC TCCGCAGGCT AAAGAGCGAG CGCGGGGGCA GGCCGGGCGG 
CCCGGGCACC AGCACGGACA GGAGCCCGAA TGGGCGACCG CCGGCGCAGG CGCCCCAGGG 
AACCCTGAGG ACCCGGGAGC TGCTCACAGA CCACCGGGTC CCCGGCCTTC TGCTCGAGGC 
CATGAAGGTG GCTGTCCGGA AGCAGCGGAA GAAGATCAAG GCCAAGATGT TAGGGACACC 
AGAGGAAGCA GAGAGCAGCT TTGGCCTATG GTATCGGGGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hepatitis C virus promotes virion secretion through cleavage of the Rab7 adaptor protein RILP.
Proceedings of the National Academy of Sciences of the United States of America113(44)12484-12489(2016 Nov)
Wozniak AL,Long A,Jones-Jamtgaard KN,Weinman SA

Parkin Modulates Endosomal Organization and Function of the Endo-Lysosomal Pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience36(8)2425-37(2016 Feb)
Song P,Trajkovic K,Tsunemi T,Krainc D

A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Cell163(3)712-23(2015 Oct)
Hein MY,Hubner NC,Poser I,Cox J,Nagaraj N,Toyoda Y,Gak IA,Weisswange I,Mansfeld J,Buchholz F,Hyman AA,Mann M

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

RILP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報