CAMP cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	CAMP
Entrez Gene ID	820
Full Name	cathelicidin antimicrobial peptide
Synonyms	CAP-18,CAP18,CRAMP,FALL-39,FALL39,HSD26,LL37
General protein information	Preferred Names cathelicidin antimicrobial peptide Names cathelicidin antimicrobial peptide 18 kDa cationic antimicrobial protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 3 Map Location: 3p21.31
Summary	This gene encodes a member of an antimicrobial peptide family, characterized by a highly conserved N-terminal signal peptide containing a cathelin domain and a structurally variable cationic antimicrobial peptide, which is produced by extracellular proteolysis from the C-terminus. In addition to its antibacterial, antifungal, and antiviral activities, the encoded protein functions in cell chemotaxis, immune mediator induction, and inflammatory response regulation. [provided by RefSeq, Sep 2014].
Disorder MIM:	600474

mRNA and Protein(s)

mRNA	Protein	Name
NM_004345.4	NP_004336.3	cathelicidin antimicrobial peptide preproprotein
NM_004345.5	NP_004336.4	cathelicidin antimicrobial peptide preproprotein

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	CAMP	NP_001003359.1
Bos taurus (cattle)	CATHL2	NP_777251.1
Bos taurus (cattle)	CATHL6	NP_777257.1
Homo sapiens (human)	CAMP	NP_004336.3
Pan troglodytes (chimpanzee)	CAMP	NP_001065283.1
Bos taurus (cattle)	LOC101907368	XP_005201109.1
Mus musculus (house mouse)	Camp	NP_034051.2
	CAMP	NP_001028681.1
Bos taurus (cattle)	CAMP	NP_777256.1
Bos taurus (cattle)	CATHL3	NP_776426.1
Bos taurus (cattle)	CATHL1	NP_777250.1
Bos taurus (cattle)	CATHL5	NP_776935.1
Rattus norvegicus (Norway rat)	Camp	NP_001094194.1
Bos taurus (cattle)	CATHL4	NP_777252.1
Bos taurus (cattle)	LOC515991	XP_002697130.2

Gene Ontology

The following CAMP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CAMP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu27407	NM_004345.4 Latest version!	Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu107668	NM_004345.5 Latest version!	Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CAMP ( NM_004345.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_004336.3 Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.

Price & Availability↑

CloneID	OHu27407
Clone ID Related Accession (Same CDS sequence)	NM_004345.4
Accession Version	NM_004345.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 522bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-28
Organism	Homo sapiens(human)
Product	cathelicidin antimicrobial peptide preproprotein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU074012.1, BC055089.1 and AA635187.1. On Sep 30, 2011 this sequence version replaced NM_004345.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.454211.1, SRR1163655.11992.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 23246832 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGGACCA TGAAGACCCA AAGGGATGGC CACTCCCTGG GGCGGTGGTC ACTGGTGCTC 
CTGCTGCTGG GCCTGGTGAT GCCTCTGGCC ATCATTGCCC AGGTCCTCAG CTACAAGGAA 
GCTGTGCTTC GTGCTATAGA TGGCATCAAC CAGCGGTCCT CGGATGCTAA CCTCTACCGC 
CTCCTGGACC TGGACCCCAG GCCCACGATG GATGGGGACC CAGACACGCC AAAGCCTGTG 
AGCTTCACAG TGAAGGAGAC AGTGTGCCCC AGGACGACAC AGCAGTCACC AGAGGATTGT 
GACTTCAAGA AGGACGGGCT GGTGAAGCGG TGTATGGGGA CAGTGACCCT CAACCAGGCC 
AGGGGCTCCT TTGACATCAG TTGTGATAAG GATAACAAGA GATTTGCCCT GCTGGGTGAT 
TTCTTCCGGA AATCTAAAGA GAAGATTGGC AAAGAGTTTA AAAGAATTGT CCAGAGAATC 
AAGGATTTTT TGCGGAATCT TGTACCCAGG ACAGAGTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004336.3
CDS	157..678
Translation	MGTMKTQRDGHSLGRWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

Target ORF information:

RefSeq Version	NM_004345.4
Organism	Homo sapiens(human)
Definition	Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004345.4

ORF Insert Sequence:

ATGGGGACCA TGAAGACCCA AAGGGATGGC CACTCCCTGG GGCGGTGGTC ACTGGTGCTC 
CTGCTGCTGG GCCTGGTGAT GCCTCTGGCC ATCATTGCCC AGGTCCTCAG CTACAAGGAA 
GCTGTGCTTC GTGCTATAGA TGGCATCAAC CAGCGGTCCT CGGATGCTAA CCTCTACCGC 
CTCCTGGACC TGGACCCCAG GCCCACGATG GATGGGGACC CAGACACGCC AAAGCCTGTG 
AGCTTCACAG TGAAGGAGAC AGTGTGCCCC AGGACGACAC AGCAGTCACC AGAGGATTGT 
GACTTCAAGA AGGACGGGCT GGTGAAGCGG TGTATGGGGA CAGTGACCCT CAACCAGGCC 
AGGGGCTCCT TTGACATCAG TTGTGATAAG GATAACAAGA GATTTGCCCT GCTGGGTGAT 
TTCTTCCGGA AATCTAAAGA GAAGATTGGC AAAGAGTTTA AAAGAATTGT CCAGAGAATC 
AAGGATTTTT TGCGGAATCT TGTACCCAGG ACAGAGTCCT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CAMP ( NM_004345.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_004336.4 Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.

Price & Availability↑

CloneID	OHu107668
Clone ID Related Accession (Same CDS sequence)	NM_004345.5
Accession Version	NM_004345.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 513bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	cathelicidin antimicrobial peptide preproprotein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from X89658.1. On Dec 27, 2018 this sequence version replaced NM_004345.4. CCDS Note: The coding region has been updated to start at a downstream in-frame start codon that is supported by conservation data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: GQ891396.1, X89658.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved MANE Ensembl match :: ENST00000652295.2/ ENSP00000498425.1 Protein has antimicrobial activity :: PMID: 23246832 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAAGACCC AAAGGGATGG CCACTCCCTG GGGCGGTGGT CACTGGTGCT CCTGCTGCTG 
GGCCTGGTGA TGCCTCTGGC CATCATTGCC CAGGTCCTCA GCTACAAGGA AGCTGTGCTT 
CGTGCTATAG ATGGCATCAA CCAGCGGTCC TCGGATGCTA ACCTCTACCG CCTCCTGGAC 
CTGGACCCCA GGCCCACGAT GGATGGGGAC CCAGACACGC CAAAGCCTGT GAGCTTCACA 
GTGAAGGAGA CAGTGTGCCC CAGGACGACA CAGCAGTCAC CAGAGGATTG TGACTTCAAG 
AAGGACGGGC TGGTGAAGCG GTGTATGGGG ACAGTGACCC TCAACCAGGC CAGGGGCTCC 
TTTGACATCA GTTGTGATAA GGATAACAAG AGATTTGCCC TGCTGGGTGA TTTCTTCCGG 
AAATCTAAAG AGAAGATTGG CAAAGAGTTT AAAAGAATTG TCCAGAGAAT CAAGGATTTT 
TTGCGGAATC TTGTACCCAG GACAGAGTCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_004336.4
CDS	18..530
Translation	MKTQRDGHSLGRWSLVLLLLGLVMPLAIIAQVLSYKEAVLRAIDGINQRSSDANLYRLLDLDPRPTMDGDPDTPKPVSFTVKETVCPRTTQQSPEDCDFKKDGLVKRCMGTVTLNQARGSFDISCDKDNKRFALLGDFFRKSKEKIGKEFKRIVQRIKDFLRNLVPRTES

Target ORF information:

RefSeq Version	NM_004345.5
Organism	Homo sapiens(human)
Definition	Homo sapiens cathelicidin antimicrobial peptide (CAMP), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_004345.5

ORF Insert Sequence:

ATGAAGACCC AAAGGGATGG CCACTCCCTG GGGCGGTGGT CACTGGTGCT CCTGCTGCTG 
GGCCTGGTGA TGCCTCTGGC CATCATTGCC CAGGTCCTCA GCTACAAGGA AGCTGTGCTT 
CGTGCTATAG ATGGCATCAA CCAGCGGTCC TCGGATGCTA ACCTCTACCG CCTCCTGGAC 
CTGGACCCCA GGCCCACGAT GGATGGGGAC CCAGACACGC CAAAGCCTGT GAGCTTCACA 
GTGAAGGAGA CAGTGTGCCC CAGGACGACA CAGCAGTCAC CAGAGGATTG TGACTTCAAG 
AAGGACGGGC TGGTGAAGCG GTGTATGGGG ACAGTGACCC TCAACCAGGC CAGGGGCTCC 
TTTGACATCA GTTGTGATAA GGATAACAAG AGATTTGCCC TGCTGGGTGA TTTCTTCCGG 
AAATCTAAAG AGAAGATTGG CAAAGAGTTT AAAAGAATTG TCCAGAGAAT CAAGGATTTT 
TTGCGGAATC TTGTACCCAG GACAGAGTCC TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.