Gene Symbol | AMN |
Entrez Gene ID | 81693 |
Full Name | amnion associated transmembrane protein |
Synonyms | PRO1028,amnionless |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is a type I transmembrane protein. It is thought to modulate bone morphogenetic protein (BMP) receptor function by serving as an accessory or coreceptor, and thus facilitates or hinders BMP binding. It is known that the mouse AMN gene is expressed in the extraembryonic visceral endoderm layer during gastrulation, but it is found to be mutated in amnionless mouse. The encoded protein has sequence similarity to short gastrulation (Sog) and procollagen IIA proteins in Drosophila. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Megaloblastic anemia-1, Norwegian type, 261100 (3) |