TTYH3 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TTYH3
Entrez Gene ID	80727
Full Name	tweety family member 3
General protein information	Preferred Names tweety family member 3 Names protein tweety homolog 3 hTTY3 tweety homolog 3
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7p22.3
Summary	This gene encodes a member of the tweety family of proteins. Members of this family function as chloride anion channels. The encoded protein functions as a calcium(2+)-activated large conductance chloride(-) channel. [provided by RefSeq, Jul 2008].
Disorder MIM:	608919

mRNA and Protein(s)

mRNA	Protein	Name
XM_011515535.2	XP_011513837.1	protein tweety homolog 3 isoform X1
XM_017012655.1	XP_016868144.1	protein tweety homolog 3 isoform X2
NM_025250.2	NP_079526.1	protein tweety homolog 3
NM_025250.3	NP_079526.1	protein tweety homolog 3
XM_017012656.1	XP_016868145.1	protein tweety homolog 3 isoform X3

Pathways from BioSystems

Homologies

Bos taurus (cattle)	TTYH3	XP_003587896.1
Drosophila melanogaster (fruit fly)	tty	NP_001259767.1
Rattus norvegicus (Norway rat)	Ttyh3	NP_001100594.1
Gallus gallus (chicken)	TTYH3	XP_414776.3
Homo sapiens (human)	TTYH3	NP_079526.1
	LOC714138	XP_001103727.2
Xenopus tropicalis (tropical clawed frog)	ttyh3	NP_001120249.1
Canis lupus familiaris (dog)	TTYH3	XP_005621241.1
Mus musculus (house mouse)	Ttyh3	NP_780483.2
Danio rerio (zebrafish)	ttyh3b	NP_001032464.1
Pan troglodytes (chimpanzee)	TTYH3	XP_003318274.1
Danio rerio (zebrafish)	LOC556314	XP_684174.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP000860	XP_316830.5

Gene Ontology
Bibliography

Related articles in PubMed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, B?ning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)

The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.
He Y, Hryciw DH, Carroll ML, Myers SA, Whitbread AK, Kumar S, Poronnik P, Hooper JD
The Journal of biological chemistry283(35)24000-10(2008 Aug)

The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels.
Suzuki M
Experimental physiology91(1)141-7(2006 Jan)

A novel human Cl(-) channel family related to Drosophila flightless locus.
Suzuki M, Mizuno A
The Journal of biological chemistry279(21)22461-8(2004 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Nedd4-2 differentially interacts with and regulates TTYH1-3
Title: The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.

The following TTYH3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TTYH3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04439	NM_025250.3 Latest version!	Homo sapiens tweety family member 3 (TTYH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu72817	XM_011515535.2 Latest version!	Homo sapiens tweety family member 3 (TTYH3), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu97522	XM_017012655.1 Latest version!	Homo sapiens tweety family member 3 (TTYH3), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu97523	XM_017012656.1 Latest version!	Homo sapiens tweety family member 3 (TTYH3), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu04439	NM_025250.2	Homo sapiens tweety family member 3 (TTYH3), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TTYH3 ( NM_025250.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_079526.1 Homo sapiens tweety family member 3 (TTYH3), mRNA.

Price & Availability↑

CloneID	OHu04439
Clone ID Related Accession (Same CDS sequence)	NM_025250.2 , NM_025250.3
Accession Version	NM_025250.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-30
Organism	Homo sapiens(human)
Product	protein tweety homolog 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL522452.3, AB051478.2, AK074158.1, AK124608.1, AF318350.1, BC069027.1 and BC041603.1. On Oct 6, 2004 this sequence version replaced NM_025250.1. ##Evidence-Data-START## Transcript exon combination :: BC152447.1, AB051478.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
TACACCTCCA GCATGAGAGC CAAATACCTC GCCACGAGCC AGCCTCGCCC TGACTCCAGC 
GGCAGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079526.1
CDS	188..1759
Translation	MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSH

Target ORF information:

RefSeq Version	NM_025250.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 3 (TTYH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025250.2

ORF Insert Sequence:

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
TACACCTCCA GCATGAGAGC CAAATACCTC GCCACGAGCC AGCCTCGCCC TGACTCCAGC 
GGCAGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH3 ( NM_025250.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079526.1 Homo sapiens tweety family member 3 (TTYH3), mRNA.

Price & Availability↑

CloneID	OHu04439
Clone ID Related Accession (Same CDS sequence)	NM_025250.2 , NM_025250.3
Accession Version	NM_025250.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1572bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-05-01
Organism	Homo sapiens(human)
Product	protein tweety homolog 3
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL522452.3, AB051478.2, AK074158.1, AK124608.1, AF318350.1, BC069027.1 and BC041603.1. On Nov 22, 2018 this sequence version replaced NM_025250.2. ##Evidence-Data-START## Transcript exon combination :: BC152447.1, AB051478.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000258796.12/ ENSP00000258796.7 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
TACACCTCCA GCATGAGAGC CAAATACCTC GCCACGAGCC AGCCTCGCCC TGACTCCAGC 
GGCAGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079526.1
CDS	171..1742
Translation	MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSH

Target ORF information:

RefSeq Version	NM_025250.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 3 (TTYH3), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_025250.3

ORF Insert Sequence:

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
TACACCTCCA GCATGAGAGC CAAATACCTC GCCACGAGCC AGCCTCGCCC TGACTCCAGC 
GGCAGCCACT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH3 ( XM_011515535.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011513837.1 Homo sapiens tweety family member 3 (TTYH3), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu72817
Clone ID Related Accession (Same CDS sequence)	XM_011515535.2
Accession Version	XM_011515535.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1581bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein tweety homolog 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011515535.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
CGCTATCTGG CTGCCCTGGA CTCTGGCAGC CACGCGGGCT GGCAGTTTAA GCCCATGGAC 
AGTGCCCGAA CGCTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011513837.1
CDS	156..1736
Translation	MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRWLGYLGLLLLDVIICLLVLVGLIRSSKGILVGVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSRYLAALDSGSHAGWQFKPMDSARTLW

Target ORF information:

RefSeq Version	XM_011515535.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 3 (TTYH3), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011515535.2

ORF Insert Sequence:

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGTGG CTGGGCTACC TGGGCCTGCT GCTGCTGGAC 
GTCATCATCT GCCTCCTGGT GCTGGTTGGC CTCATCCGCA GCTCCAAGGG CATCCTGGTG 
GGGGTCTGCC TGCTGGGAGT CCTGGCCCTG GTCATCAGCT GGGGCGCGCT GGGCTTGGAG 
CTGGCTGTGT CCGTGGGCTC CAGCGACTTC TGTGTGGACC CTGACGCCTA CGTGACCAAA 
ATGGTGGAGG AGTACTCGGT GCTGAGTGGG GACATCCTGC AGTACTACCT GGCCTGCTCG 
CCCCGCGCCG CCAACCCCTT CCAGCAGAAG CTGTCGGGCA GCCACAAGGC ACTGGTGGAG 
ATGCAGGATG TCGTGGCTGA GCTTCTGAGG ACCGTCCCCT GGGAGCAGCC GGCCACTAAG 
GACCCCCTCC TCCGCGTCCA GGAGGTGCTG AATGGCACGG AGGTGAACCT GCAGCACCTC 
ACCGCCCTGG TGGACTGCCG CAGCCTGCAT CTGGACTACG TGCAAGCGCT GACCGGCTTC 
TGCTATGACG GCGTGGAGGG CCTCATCTAC CTGGCCCTCT TCTCCTTCGT CACAGCCCTC 
ATGTTCAGCT CCATCGTCTG CAGCGTCCCG CACACCTGGC AGCAAAAGAG AGGCCCTGAT 
GAGGACGGGG AGGAGGAGGC CGCTCCAGGG CCGCGGCAGG CGCACGACAG CCTCTACCGC 
GTCCACATGC CCAGCCTGTA CAGCTGTGGC AGCAGCTACG GCAGTGAGAC CAGCATCCCG 
GCCGCGGCCC ACACCGTCAG CAACGCCCCG GTCACTGAGT ACATGAGCCA GAACGCTAAT 
TTCCAGAACC CCCGCTGTGA GAACACCCCA CTCATTGGGC GCGAGTCCCC GCCGCCCTCA 
CGCTATCTGG CTGCCCTGGA CTCTGGCAGC CACGCGGGCT GGCAGTTTAA GCCCATGGAC 
AGTGCCCGAA CGCTGTGGTA G

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH3 ( XM_017012655.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868144.1 Homo sapiens tweety family member 3 (TTYH3), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu97522
Clone ID Related Accession (Same CDS sequence)	XM_017012655.1
Accession Version	XM_017012655.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1485bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein tweety homolog 3 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGGTC TGCCTGCTGG GAGTCCTGGC CCTGGTCATC 
AGCTGGGGCG CGCTGGGCTT GGAGCTGGCT GTGTCCGTGG GCTCCAGCGA CTTCTGTGTG 
GACCCTGACG CCTACGTGAC CAAAATGGTG GAGGAGTACT CGGTGCTGAG TGGGGACATC 
CTGCAGTACT ACCTGGCCTG CTCGCCCCGC GCCGCCAACC CCTTCCAGCA GAAGCTGTCG 
GGCAGCCACA AGGCACTGGT GGAGATGCAG GATGTCGTGG CTGAGCTTCT GAGGACCGTC 
CCCTGGGAGC AGCCGGCCAC TAAGGACCCC CTCCTCCGCG TCCAGGAGGT GCTGAATGGC 
ACGGAGGTGA ACCTGCAGCA CCTCACCGCC CTGGTGGACT GCCGCAGCCT GCATCTGGAC 
TACGTGCAAG CGCTGACCGG CTTCTGCTAT GACGGCGTGG AGGGCCTCAT CTACCTGGCC 
CTCTTCTCCT TCGTCACAGC CCTCATGTTC AGCTCCATCG TCTGCAGCGT CCCGCACACC 
TGGCAGCAAA AGAGAGGCCC TGATGAGGAC GGGGAGGAGG AGGCCGCTCC AGGGCCGCGG 
CAGGCGCACG ACAGCCTCTA CCGCGTCCAC ATGCCCAGCC TGTACAGCTG TGGCAGCAGC 
TACGGCAGTG AGACCAGCAT CCCGGCCGCG GCCCACACCG TCAGCAACGC CCCGGTCACT 
GAGTACATGA GCCAGAACGC TAATTTCCAG AACCCCCGCT GTGAGAACAC CCCACTCATT 
GGGCGCGAGT CCCCGCCGCC CTCACGCTAT CTGGCTGCCC TGGACTCTGG CAGCCACGCG 
GGCTGGCAGT TTAAGCCCAT GGACAGTGCC CGAACGCTGT GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868144.1
CDS	158..1642
Translation	MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSRYLAALDSGSHAGWQFKPMDSARTLW

Target ORF information:

RefSeq Version	XM_017012655.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 3 (TTYH3), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012655.1

ORF Insert Sequence:

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGGTC TGCCTGCTGG GAGTCCTGGC CCTGGTCATC 
AGCTGGGGCG CGCTGGGCTT GGAGCTGGCT GTGTCCGTGG GCTCCAGCGA CTTCTGTGTG 
GACCCTGACG CCTACGTGAC CAAAATGGTG GAGGAGTACT CGGTGCTGAG TGGGGACATC 
CTGCAGTACT ACCTGGCCTG CTCGCCCCGC GCCGCCAACC CCTTCCAGCA GAAGCTGTCG 
GGCAGCCACA AGGCACTGGT GGAGATGCAG GATGTCGTGG CTGAGCTTCT GAGGACCGTC 
CCCTGGGAGC AGCCGGCCAC TAAGGACCCC CTCCTCCGCG TCCAGGAGGT GCTGAATGGC 
ACGGAGGTGA ACCTGCAGCA CCTCACCGCC CTGGTGGACT GCCGCAGCCT GCATCTGGAC 
TACGTGCAAG CGCTGACCGG CTTCTGCTAT GACGGCGTGG AGGGCCTCAT CTACCTGGCC 
CTCTTCTCCT TCGTCACAGC CCTCATGTTC AGCTCCATCG TCTGCAGCGT CCCGCACACC 
TGGCAGCAAA AGAGAGGCCC TGATGAGGAC GGGGAGGAGG AGGCCGCTCC AGGGCCGCGG 
CAGGCGCACG ACAGCCTCTA CCGCGTCCAC ATGCCCAGCC TGTACAGCTG TGGCAGCAGC 
TACGGCAGTG AGACCAGCAT CCCGGCCGCG GCCCACACCG TCAGCAACGC CCCGGTCACT 
GAGTACATGA GCCAGAACGC TAATTTCCAG AACCCCCGCT GTGAGAACAC CCCACTCATT 
GGGCGCGAGT CCCCGCCGCC CTCACGCTAT CTGGCTGCCC TGGACTCTGG CAGCCACGCG 
GGCTGGCAGT TTAAGCCCAT GGACAGTGCC CGAACGCTGT GGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TTYH3 ( XM_017012656.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016868145.1 Homo sapiens tweety family member 3 (TTYH3), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu97523
Clone ID Related Accession (Same CDS sequence)	XM_017012656.1
Accession Version	XM_017012656.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1476bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein tweety homolog 3 isoform X3
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000007.14) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGGTC TGCCTGCTGG GAGTCCTGGC CCTGGTCATC 
AGCTGGGGCG CGCTGGGCTT GGAGCTGGCT GTGTCCGTGG GCTCCAGCGA CTTCTGTGTG 
GACCCTGACG CCTACGTGAC CAAAATGGTG GAGGAGTACT CGGTGCTGAG TGGGGACATC 
CTGCAGTACT ACCTGGCCTG CTCGCCCCGC GCCGCCAACC CCTTCCAGCA GAAGCTGTCG 
GGCAGCCACA AGGCACTGGT GGAGATGCAG GATGTCGTGG CTGAGCTTCT GAGGACCGTC 
CCCTGGGAGC AGCCGGCCAC TAAGGACCCC CTCCTCCGCG TCCAGGAGGT GCTGAATGGC 
ACGGAGGTGA ACCTGCAGCA CCTCACCGCC CTGGTGGACT GCCGCAGCCT GCATCTGGAC 
TACGTGCAAG CGCTGACCGG CTTCTGCTAT GACGGCGTGG AGGGCCTCAT CTACCTGGCC 
CTCTTCTCCT TCGTCACAGC CCTCATGTTC AGCTCCATCG TCTGCAGCGT CCCGCACACC 
TGGCAGCAAA AGAGAGGCCC TGATGAGGAC GGGGAGGAGG AGGCCGCTCC AGGGCCGCGG 
CAGGCGCACG ACAGCCTCTA CCGCGTCCAC ATGCCCAGCC TGTACAGCTG TGGCAGCAGC 
TACGGCAGTG AGACCAGCAT CCCGGCCGCG GCCCACACCG TCAGCAACGC CCCGGTCACT 
GAGTACATGA GCCAGAACGC TAATTTCCAG AACCCCCGCT GTGAGAACAC CCCACTCATT 
GGGCGCGAGT CCCCGCCGCC CTCATACACC TCCAGCATGA GAGCCAAATA CCTCGCCACG 
AGCCAGCCTC GCCCTGACTC CAGCGGCAGC CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016868145.1
CDS	156..1631
Translation	MAGVSYAAPWWVSLLHRLPHFDLSWEATSSQFRPEDTDYQQALLLLGAAALACLALDLLFLLFYSFWLCCRRRKSEEHLDADCCCTAWCVIIATLVCSAGIAVGFYGNGETSDGIHRATYSLRHANRTVAGVQDRVWDTAVGLNHTAEPSLQTLERQLAGRPEPLRAVQRLQGLLETLLGYTAAIPFWRNTAVSLEVLAEQVDLYDWYRVCLLGVLALVISWGALGLELAVSVGSSDFCVDPDAYVTKMVEEYSVLSGDILQYYLACSPRAANPFQQKLSGSHKALVEMQDVVAELLRTVPWEQPATKDPLLRVQEVLNGTEVNLQHLTALVDCRSLHLDYVQALTGFCYDGVEGLIYLALFSFVTALMFSSIVCSVPHTWQQKRGPDEDGEEEAAPGPRQAHDSLYRVHMPSLYSCGSSYGSETSIPAAAHTVSNAPVTEYMSQNANFQNPRCENTPLIGRESPPPSYTSSMRAKYLATSQPRPDSSGSH

Target ORF information:

RefSeq Version	XM_017012656.1
Organism	Homo sapiens(human)
Definition	Homo sapiens tweety family member 3 (TTYH3), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017012656.1

ORF Insert Sequence:

ATGGCCGGGG TCAGCTACGC GGCGCCCTGG TGGGTGAGCC TCCTGCACCG GCTGCCCCAC 
TTCGACCTGA GCTGGGAGGC CACTAGCAGC CAGTTCCGGC CCGAGGACAC CGACTACCAG 
CAGGCCCTGC TGCTCCTGGG GGCCGCCGCC CTGGCCTGCC TCGCCCTGGA CCTCCTCTTC 
CTGCTCTTCT ACTCCTTCTG GCTGTGCTGC CGGCGGCGCA AGAGCGAGGA GCACCTGGAC 
GCCGACTGCT GCTGCACGGC CTGGTGTGTC ATCATCGCCA CGCTGGTGTG CAGCGCCGGC 
ATCGCAGTGG GATTCTACGG CAACGGGGAG ACCAGTGATG GCATCCATAG GGCCACCTAC 
TCGCTCCGCC ACGCCAACCG CACGGTGGCC GGGGTCCAGG ACCGCGTGTG GGACACGGCG 
GTGGGGCTGA ACCACACGGC GGAGCCCAGC CTGCAGACCC TGGAGCGGCA GCTGGCCGGG 
CGGCCCGAGC CCCTGCGAGC CGTACAGAGG CTGCAGGGCC TGCTGGAGAC GCTGCTGGGC 
TACACGGCCG CCATCCCCTT TTGGAGGAAC ACGGCGGTGT CGCTGGAGGT GCTGGCGGAG 
CAGGTGGATC TCTACGACTG GTACAGGGTC TGCCTGCTGG GAGTCCTGGC CCTGGTCATC 
AGCTGGGGCG CGCTGGGCTT GGAGCTGGCT GTGTCCGTGG GCTCCAGCGA CTTCTGTGTG 
GACCCTGACG CCTACGTGAC CAAAATGGTG GAGGAGTACT CGGTGCTGAG TGGGGACATC 
CTGCAGTACT ACCTGGCCTG CTCGCCCCGC GCCGCCAACC CCTTCCAGCA GAAGCTGTCG 
GGCAGCCACA AGGCACTGGT GGAGATGCAG GATGTCGTGG CTGAGCTTCT GAGGACCGTC 
CCCTGGGAGC AGCCGGCCAC TAAGGACCCC CTCCTCCGCG TCCAGGAGGT GCTGAATGGC 
ACGGAGGTGA ACCTGCAGCA CCTCACCGCC CTGGTGGACT GCCGCAGCCT GCATCTGGAC 
TACGTGCAAG CGCTGACCGG CTTCTGCTAT GACGGCGTGG AGGGCCTCAT CTACCTGGCC 
CTCTTCTCCT TCGTCACAGC CCTCATGTTC AGCTCCATCG TCTGCAGCGT CCCGCACACC 
TGGCAGCAAA AGAGAGGCCC TGATGAGGAC GGGGAGGAGG AGGCCGCTCC AGGGCCGCGG 
CAGGCGCACG ACAGCCTCTA CCGCGTCCAC ATGCCCAGCC TGTACAGCTG TGGCAGCAGC 
TACGGCAGTG AGACCAGCAT CCCGGCCGCG GCCCACACCG TCAGCAACGC CCCGGTCACT 
GAGTACATGA GCCAGAACGC TAATTTCCAG AACCCCCGCT GTGAGAACAC CCCACTCATT 
GGGCGCGAGT CCCCGCCGCC CTCATACACC TCCAGCATGA GAGCCAAATA CCTCGCCACG 
AGCCAGCCTC GCCCTGACTC CAGCGGCAGC CACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,B?ning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH

Large-scale proteomics and phosphoproteomics of urinary exosomes.
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
Gonzales PA,Pisitkun T,Hoffert JD,Tchapyjnikov D,Star RA,Kleta R,Wang NS,Knepper MA

The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the Tweety family of chloride ion channels.
The Journal of biological chemistry283(35)24000-10(2008 Aug)
He Y,Hryciw DH,Carroll ML,Myers SA,Whitbread AK,Kumar S,Poronnik P,Hooper JD

The Drosophila tweety family: molecular candidates for large-conductance Ca2+-activated Cl- channels.
Experimental physiology91(1)141-7(2006 Jan)
Suzuki M

A novel human Cl(-) channel family related to Drosophila flightless locus.
The Journal of biological chemistry279(21)22461-8(2004 May)
Suzuki M,Mizuno A

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TTYH3 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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見積依頼

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電話

FAX

オンラインフォーム