ZNF408 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ZNF408
Entrez Gene ID	79797
Full Name	zinc finger protein 408
Synonyms	EVR6,RP72
General protein information	Preferred Names zinc finger protein 408 Names zinc finger protein 408 PR domain zinc finger protein 17
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 11 Map Location: 11p11.2
Summary	The protein encoded by this gene contains ten tandem zinc fingers and an N-terminal SET domain, so it is likely a DNA binding protein that interacts with other proteins. In adults, the encoded protein is expressed most highly in retina. Consequently, defects in this gene have been associated with familial exudative vitreoretinopathy (FEVR) and retinitis pigmentosa (RP). [provided by RefSeq, Dec 2016].
Disorder MIM:	616454
Disorder Html:	?Exudative vitreoretinopathy 6, 616468 (3); Retinitis pigmentosa 72, 616469 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001184751.1	NP_001171680.1	zinc finger protein 408 isoform 2
NM_024741.3	NP_079017.1	zinc finger protein 408 isoform 1
NM_024741.2	NP_079017.1	zinc finger protein 408 isoform 1
NM_001184751.2	NP_001171680.1	zinc finger protein 408 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Zfp408	NP_001028623.1
Rattus norvegicus (Norway rat)	LOC100362202	XP_003749580.1
	ZNF408	XP_001111210.1
Canis lupus familiaris (dog)	ZNF408	XP_003639743.2
Bos taurus (cattle)	ZNF408	NP_001180086.1
Danio rerio (zebrafish)	LOC793421	XP_001333167.1
Homo sapiens (human)	ZNF408	NP_079017.1
Pan troglodytes (chimpanzee)	ZNF408	XP_508399.1
Xenopus tropicalis (tropical clawed frog)	znf408	XP_004913446.1

Gene Ontology
Bibliography

Related articles in PubMed

Exome sequencing confirms ZNF408 mutations as a cause of familial retinitis pigmentosa.
Habibi I, Chebil A, Kort F, Schorderet DF, El Matri L
Ophthalmic genetics38(5)494-497(2017 Sep-Oct)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Several novel mutations (missense, non-stop and insertion) were detected in the coding regions of FZD4, TSPAN12 and ZNF408 genes among the unrelated vitreoretinopathy probands.
Title: Mutation spectrum of the FZD-4, TSPAN12 AND ZNF408 genes in Indian FEVR patients.

ZNF408, previously associated with Familial Exudative Vitreoretinopathy (FEVR), is a new gene causing autosomal recessive rtinitis pigmentosa.
Title: Whole-exome sequencing reveals ZNF408 as a new gene associated with autosomal recessive retinitis pigmentosa with vitreal alterations.

Data indicate ZNF408 missense variant (p.Ser126Asn) in 132 familial exudative vitreoretinopathy (FEVR) individuals in a Japanese family.
Title: ZNF408 is mutated in familial exudative vitreoretinopathy and is crucial for the development of zebrafish retinal vasculature.

The following ZNF408 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZNF408 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu04217	NM_024741.3 Latest version!	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu04815	NM_001184751.2 Latest version!	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$496.30 $709.00
View Old Accession Versions >>
OHu04217	NM_024741.2	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu04815	NM_001184751.1	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$496.30 $709.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ZNF408 ( NM_024741.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_079017.1 Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04217
Clone ID Related Accession (Same CDS sequence)	NM_024741.3 , NM_024741.2
Accession Version	NM_024741.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	zinc finger protein 408 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK022889.1, BC015708.2 and AW246726.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_024741.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC015708.2, SRR1660809.48678.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000311764.3/ ENSP00000309606.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGG CGGAGGAGCT GCTCTTGGAG GGGAAGAAGG CGCTGCAACT CGCCCGCGAG 
CCGCGCCTGG GCCTGGACTT AGGATGGAAC CCTTCCGGAG AAGGCTGTAC GCAGGGCCTC 
AAAGACGTCC CACCCGAGCC GACCCGAGAC ATCCTCGCTT TAAAGAGCCT TCCCCGGGGC 
TTGGCCCTTG GCCCCTCACT CGCCAAGGAA CAGCGCTTGG GGGTCTGGTG TGTCGGGGAC 
CCCCTGCAGC CCGGCCTGCT GTGGGGGCCG CTGGAAGAGG AGTCTGCCTC CAAGGAGAAG 
GGCGAGGGAG TAAAGCCACG GCAGGAGGAG AACCTGTCAT TAGGCCCATG GGGAGACGTG 
TGTGCCTGTG AGCAGAGTTC TGGCTGGACT AGCTTGGTAC AACGGGGCAG GCTGGAGAGT 
GAGGGAAATG TGGCCCCAGT GCGGATCAGC GAGAGGCTTC ATCTGCAAGT GTACCAGCTG 
GTGCTGCCAG GCTCTGAACT GCTGCTGTGG CCCCAGCCTT CCTCTGAGGG CCCAAGTCTC 
ACCCAGCCTG GGCTGGACAA AGAGGCAGCT GTAGCAGTGG TGACAGAAGT GGAGTCTGCT 
GTACAGCAGG AAGTGGCCTC CCCTGGGGAG GATGCAGCAG AACCTTGCAT AGATCCTGGT 
TCCCAGTCAC CCTCTGGCAT CCAGGCAGAG AATATGGTGA GCCCTGGACT TAAGTTCCCA 
ACCCAGGACC GAATTTCCAA GGATAGCCAG CCACTTGGCC CATTGCTTCA GGATGGCGAC 
GTGGATGAGG AATGCCCGGC CCAGGCACAG ATGCCACCTG AACTTCAGAG CAATTCGGCT 
ACCCAGCAGG ACCCAGATGG CAGTGGAGCC AGTTTCTCAT CTTCTGCCAG GGGCACCCAG 
CCGCATGGCT ACCTGGCCAA GAAGTTACAC AGCCCCAGTG ATCAGTGCCC ACCCAGAGCA 
AAGACCCCAG AGCCTGGAGC CCAGCAGTCT GGCTTCCCTA CACTCTCGCG GAGCCCTCCT 
GGCCCAGCAG GAAGCTCCCC AAAGCAGGGG CGACGGTACC GGTGTGGAGA GTGTGGCAAG 
GCATTCCTAC AGCTGTGCCA CCTAAAGAAG CACGCATTTG TGCACACGGG CCACAAGCCC 
TTTCTTTGCA CTGAGTGTGG CAAGAGCTAT AGCTCAGAGG AGAGCTTCAA AGCCCATATG 
CTGGGCCACC GTGGGGTGCG GCCCTTCCCC TGTCCACAAT GCGACAAGGC CTATGGCACC 
CAGCGAGACC TCAAAGAGCA CCAGGTGGTA CATTCAGGTG CCCGGCCCTT TGCTTGTGAC 
CAGTGTGGCA AGGCCTTTGC CCGCCGGCCC TCCCTGCGGC TGCATCGCAA GACCCACCAG 
GTGCCAGCTG CCCCTGCCCC TTGCCCATGC CCTGTGTGTG GGCGGCCCCT GGCCAACCAG 
GGCTCCCTGC GGAACCATAT GAGGCTCCAT ACAGGAGAAA AGCCTTTCCT GTGCCCGCAC 
TGTGGCCGGG CGTTTCGTCA GCGGGGCAAC CTGCGTGGGC ATTTGCGGCT CCACACCGGG 
GAGCGTCCTT ACCGCTGCCC ACACTGTGCC GATGCCTTCC CCCAGCTGCC TGAACTGCGG 
CGCCATCTCA TCTCACACAC CGGGGAGGCC CACTTGTGCC CGGTGTGTGG CAAGGCCCTC 
CGAGACCCAC ACACGCTCCG AGCTCACGAG CGCCTGCACT CCGGAGAGAG GCCCTTTCCC 
TGTCCCCAGT GTGGCCGTGC TTACACGCTG GCCACCAAGC TGCGGCGCCA CCTCAAATCT 
CACTTGGAGG ACAAGCCCTA CCGCTGCCCC ACCTGTGGCA TGGGCTACAC CCTCCCGCAG 
AGCCTCAGGC GGCATCAGCT CAGTCACCGG CCTGAGGCAC CCTGCAGCCC ACCCTCTGTG 
CCTTCTGCTG CTTCTGAGCC CACTGTGGTG CTCCTGCAGG CTGAGCCACA ACTGCTGGAC 
ACACACAGAG AGGAGGAAGT CTCCCCCGCC AGGGATGTTG TTGAGGTCAC CATTTCAGAA 
AGCCAGGAGA AGTGCTTTGT GGTGCCAGAG GAGCCAGATG CCGCCCCCAG CCTGGTGCTA 
ATCCATAAGG ACATGGGCCT CGGCGCCTGG GCAGAGGTGG TGGAGGTGGA GATGGGCACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079017.1
CDS	18..2180
Translation	MEEAEELLLEGKKALQLAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT

Target ORF information:

RefSeq Version	NM_024741.3
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024741.3

ORF Insert Sequence:

ATGGAGGAGG CGGAGGAGCT GCTCTTGGAG GGGAAGAAGG CGCTGCAACT CGCCCGCGAG 
CCGCGCCTGG GCCTGGACTT AGGATGGAAC CCTTCCGGAG AAGGCTGTAC GCAGGGCCTC 
AAAGACGTCC CACCCGAGCC GACCCGAGAC ATCCTCGCTT TAAAGAGCCT TCCCCGGGGC 
TTGGCCCTTG GCCCCTCACT CGCCAAGGAA CAGCGCTTGG GGGTCTGGTG TGTCGGGGAC 
CCCCTGCAGC CCGGCCTGCT GTGGGGGCCG CTGGAAGAGG AGTCTGCCTC CAAGGAGAAG 
GGCGAGGGAG TAAAGCCACG GCAGGAGGAG AACCTGTCAT TAGGCCCATG GGGAGACGTG 
TGTGCCTGTG AGCAGAGTTC TGGCTGGACT AGCTTGGTAC AACGGGGCAG GCTGGAGAGT 
GAGGGAAATG TGGCCCCAGT GCGGATCAGC GAGAGGCTTC ATCTGCAAGT GTACCAGCTG 
GTGCTGCCAG GCTCTGAACT GCTGCTGTGG CCCCAGCCTT CCTCTGAGGG CCCAAGTCTC 
ACCCAGCCTG GGCTGGACAA AGAGGCAGCT GTAGCAGTGG TGACAGAAGT GGAGTCTGCT 
GTACAGCAGG AAGTGGCCTC CCCTGGGGAG GATGCAGCAG AACCTTGCAT AGATCCTGGT 
TCCCAGTCAC CCTCTGGCAT CCAGGCAGAG AATATGGTGA GCCCTGGACT TAAGTTCCCA 
ACCCAGGACC GAATTTCCAA GGATAGCCAG CCACTTGGCC CATTGCTTCA GGATGGCGAC 
GTGGATGAGG AATGCCCGGC CCAGGCACAG ATGCCACCTG AACTTCAGAG CAATTCGGCT 
ACCCAGCAGG ACCCAGATGG CAGTGGAGCC AGTTTCTCAT CTTCTGCCAG GGGCACCCAG 
CCGCATGGCT ACCTGGCCAA GAAGTTACAC AGCCCCAGTG ATCAGTGCCC ACCCAGAGCA 
AAGACCCCAG AGCCTGGAGC CCAGCAGTCT GGCTTCCCTA CACTCTCGCG GAGCCCTCCT 
GGCCCAGCAG GAAGCTCCCC AAAGCAGGGG CGACGGTACC GGTGTGGAGA GTGTGGCAAG 
GCATTCCTAC AGCTGTGCCA CCTAAAGAAG CACGCATTTG TGCACACGGG CCACAAGCCC 
TTTCTTTGCA CTGAGTGTGG CAAGAGCTAT AGCTCAGAGG AGAGCTTCAA AGCCCATATG 
CTGGGCCACC GTGGGGTGCG GCCCTTCCCC TGTCCACAAT GCGACAAGGC CTATGGCACC 
CAGCGAGACC TCAAAGAGCA CCAGGTGGTA CATTCAGGTG CCCGGCCCTT TGCTTGTGAC 
CAGTGTGGCA AGGCCTTTGC CCGCCGGCCC TCCCTGCGGC TGCATCGCAA GACCCACCAG 
GTGCCAGCTG CCCCTGCCCC TTGCCCATGC CCTGTGTGTG GGCGGCCCCT GGCCAACCAG 
GGCTCCCTGC GGAACCATAT GAGGCTCCAT ACAGGAGAAA AGCCTTTCCT GTGCCCGCAC 
TGTGGCCGGG CGTTTCGTCA GCGGGGCAAC CTGCGTGGGC ATTTGCGGCT CCACACCGGG 
GAGCGTCCTT ACCGCTGCCC ACACTGTGCC GATGCCTTCC CCCAGCTGCC TGAACTGCGG 
CGCCATCTCA TCTCACACAC CGGGGAGGCC CACTTGTGCC CGGTGTGTGG CAAGGCCCTC 
CGAGACCCAC ACACGCTCCG AGCTCACGAG CGCCTGCACT CCGGAGAGAG GCCCTTTCCC 
TGTCCCCAGT GTGGCCGTGC TTACACGCTG GCCACCAAGC TGCGGCGCCA CCTCAAATCT 
CACTTGGAGG ACAAGCCCTA CCGCTGCCCC ACCTGTGGCA TGGGCTACAC CCTCCCGCAG 
AGCCTCAGGC GGCATCAGCT CAGTCACCGG CCTGAGGCAC CCTGCAGCCC ACCCTCTGTG 
CCTTCTGCTG CTTCTGAGCC CACTGTGGTG CTCCTGCAGG CTGAGCCACA ACTGCTGGAC 
ACACACAGAG AGGAGGAAGT CTCCCCCGCC AGGGATGTTG TTGAGGTCAC CATTTCAGAA 
AGCCAGGAGA AGTGCTTTGT GGTGCCAGAG GAGCCAGATG CCGCCCCCAG CCTGGTGCTA 
ATCCATAAGG ACATGGGCCT CGGCGCCTGG GCAGAGGTGG TGGAGGTGGA GATGGGCACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZNF408 ( NM_024741.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_079017.1 Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu04217
Clone ID Related Accession (Same CDS sequence)	NM_024741.3 , NM_024741.2
Accession Version	NM_024741.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2163bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	zinc finger protein 408 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA015297.1, AK022889.1, BC015708.2 and AW246726.1. This sequence is a reference standard in the RefSeqGene project. On May 15, 2010 this sequence version replaced NM_024741.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF346626.1, AK022889.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGAGG CGGAGGAGCT GCTCTTGGAG GGGAAGAAGG CGCTGCAACT CGCCCGCGAG 
CCGCGCCTGG GCCTGGACTT AGGATGGAAC CCTTCCGGAG AAGGCTGTAC GCAGGGCCTC 
AAAGACGTCC CACCCGAGCC GACCCGAGAC ATCCTCGCTT TAAAGAGCCT TCCCCGGGGC 
TTGGCCCTTG GCCCCTCACT CGCCAAGGAA CAGCGCTTGG GGGTCTGGTG TGTCGGGGAC 
CCCCTGCAGC CCGGCCTGCT GTGGGGGCCG CTGGAAGAGG AGTCTGCCTC CAAGGAGAAG 
GGCGAGGGAG TAAAGCCACG GCAGGAGGAG AACCTGTCAT TAGGCCCATG GGGAGACGTG 
TGTGCCTGTG AGCAGAGTTC TGGCTGGACT AGCTTGGTAC AACGGGGCAG GCTGGAGAGT 
GAGGGAAATG TGGCCCCAGT GCGGATCAGC GAGAGGCTTC ATCTGCAAGT GTACCAGCTG 
GTGCTGCCAG GCTCTGAACT GCTGCTGTGG CCCCAGCCTT CCTCTGAGGG CCCAAGTCTC 
ACCCAGCCTG GGCTGGACAA AGAGGCAGCT GTAGCAGTGG TGACAGAAGT GGAGTCTGCT 
GTACAGCAGG AAGTGGCCTC CCCTGGGGAG GATGCAGCAG AACCTTGCAT AGATCCTGGT 
TCCCAGTCAC CCTCTGGCAT CCAGGCAGAG AATATGGTGA GCCCTGGACT TAAGTTCCCA 
ACCCAGGACC GAATTTCCAA GGATAGCCAG CCACTTGGCC CATTGCTTCA GGATGGCGAC 
GTGGATGAGG AATGCCCGGC CCAGGCACAG ATGCCACCTG AACTTCAGAG CAATTCGGCT 
ACCCAGCAGG ACCCAGATGG CAGTGGAGCC AGTTTCTCAT CTTCTGCCAG GGGCACCCAG 
CCGCATGGCT ACCTGGCCAA GAAGTTACAC AGCCCCAGTG ATCAGTGCCC ACCCAGAGCA 
AAGACCCCAG AGCCTGGAGC CCAGCAGTCT GGCTTCCCTA CACTCTCGCG GAGCCCTCCT 
GGCCCAGCAG GAAGCTCCCC AAAGCAGGGG CGACGGTACC GGTGTGGAGA GTGTGGCAAG 
GCATTCCTAC AGCTGTGCCA CCTAAAGAAG CACGCATTTG TGCACACGGG CCACAAGCCC 
TTTCTTTGCA CTGAGTGTGG CAAGAGCTAT AGCTCAGAGG AGAGCTTCAA AGCCCATATG 
CTGGGCCACC GTGGGGTGCG GCCCTTCCCC TGTCCACAAT GCGACAAGGC CTATGGCACC 
CAGCGAGACC TCAAAGAGCA CCAGGTGGTA CATTCAGGTG CCCGGCCCTT TGCTTGTGAC 
CAGTGTGGCA AGGCCTTTGC CCGCCGGCCC TCCCTGCGGC TGCATCGCAA GACCCACCAG 
GTGCCAGCTG CCCCTGCCCC TTGCCCATGC CCTGTGTGTG GGCGGCCCCT GGCCAACCAG 
GGCTCCCTGC GGAACCATAT GAGGCTCCAT ACAGGAGAAA AGCCTTTCCT GTGCCCGCAC 
TGTGGCCGGG CGTTTCGTCA GCGGGGCAAC CTGCGTGGGC ATTTGCGGCT CCACACCGGG 
GAGCGTCCTT ACCGCTGCCC ACACTGTGCC GATGCCTTCC CCCAGCTGCC TGAACTGCGG 
CGCCATCTCA TCTCACACAC CGGGGAGGCC CACTTGTGCC CGGTGTGTGG CAAGGCCCTC 
CGAGACCCAC ACACGCTCCG AGCTCACGAG CGCCTGCACT CCGGAGAGAG GCCCTTTCCC 
TGTCCCCAGT GTGGCCGTGC TTACACGCTG GCCACCAAGC TGCGGCGCCA CCTCAAATCT 
CACTTGGAGG ACAAGCCCTA CCGCTGCCCC ACCTGTGGCA TGGGCTACAC CCTCCCGCAG 
AGCCTCAGGC GGCATCAGCT CAGTCACCGG CCTGAGGCAC CCTGCAGCCC ACCCTCTGTG 
CCTTCTGCTG CTTCTGAGCC CACTGTGGTG CTCCTGCAGG CTGAGCCACA ACTGCTGGAC 
ACACACAGAG AGGAGGAAGT CTCCCCCGCC AGGGATGTTG TTGAGGTCAC CATTTCAGAA 
AGCCAGGAGA AGTGCTTTGT GGTGCCAGAG GAGCCAGATG CCGCCCCCAG CCTGGTGCTA 
ATCCATAAGG ACATGGGCCT CGGCGCCTGG GCAGAGGTGG TGGAGGTGGA GATGGGCACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_079017.1
CDS	282..2444
Translation	MEEAEELLLEGKKALQLAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT

Target ORF information:

RefSeq Version	NM_024741.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_024741.2

ORF Insert Sequence:

ATGGAGGAGG CGGAGGAGCT GCTCTTGGAG GGGAAGAAGG CGCTGCAACT CGCCCGCGAG 
CCGCGCCTGG GCCTGGACTT AGGATGGAAC CCTTCCGGAG AAGGCTGTAC GCAGGGCCTC 
AAAGACGTCC CACCCGAGCC GACCCGAGAC ATCCTCGCTT TAAAGAGCCT TCCCCGGGGC 
TTGGCCCTTG GCCCCTCACT CGCCAAGGAA CAGCGCTTGG GGGTCTGGTG TGTCGGGGAC 
CCCCTGCAGC CCGGCCTGCT GTGGGGGCCG CTGGAAGAGG AGTCTGCCTC CAAGGAGAAG 
GGCGAGGGAG TAAAGCCACG GCAGGAGGAG AACCTGTCAT TAGGCCCATG GGGAGACGTG 
TGTGCCTGTG AGCAGAGTTC TGGCTGGACT AGCTTGGTAC AACGGGGCAG GCTGGAGAGT 
GAGGGAAATG TGGCCCCAGT GCGGATCAGC GAGAGGCTTC ATCTGCAAGT GTACCAGCTG 
GTGCTGCCAG GCTCTGAACT GCTGCTGTGG CCCCAGCCTT CCTCTGAGGG CCCAAGTCTC 
ACCCAGCCTG GGCTGGACAA AGAGGCAGCT GTAGCAGTGG TGACAGAAGT GGAGTCTGCT 
GTACAGCAGG AAGTGGCCTC CCCTGGGGAG GATGCAGCAG AACCTTGCAT AGATCCTGGT 
TCCCAGTCAC CCTCTGGCAT CCAGGCAGAG AATATGGTGA GCCCTGGACT TAAGTTCCCA 
ACCCAGGACC GAATTTCCAA GGATAGCCAG CCACTTGGCC CATTGCTTCA GGATGGCGAC 
GTGGATGAGG AATGCCCGGC CCAGGCACAG ATGCCACCTG AACTTCAGAG CAATTCGGCT 
ACCCAGCAGG ACCCAGATGG CAGTGGAGCC AGTTTCTCAT CTTCTGCCAG GGGCACCCAG 
CCGCATGGCT ACCTGGCCAA GAAGTTACAC AGCCCCAGTG ATCAGTGCCC ACCCAGAGCA 
AAGACCCCAG AGCCTGGAGC CCAGCAGTCT GGCTTCCCTA CACTCTCGCG GAGCCCTCCT 
GGCCCAGCAG GAAGCTCCCC AAAGCAGGGG CGACGGTACC GGTGTGGAGA GTGTGGCAAG 
GCATTCCTAC AGCTGTGCCA CCTAAAGAAG CACGCATTTG TGCACACGGG CCACAAGCCC 
TTTCTTTGCA CTGAGTGTGG CAAGAGCTAT AGCTCAGAGG AGAGCTTCAA AGCCCATATG 
CTGGGCCACC GTGGGGTGCG GCCCTTCCCC TGTCCACAAT GCGACAAGGC CTATGGCACC 
CAGCGAGACC TCAAAGAGCA CCAGGTGGTA CATTCAGGTG CCCGGCCCTT TGCTTGTGAC 
CAGTGTGGCA AGGCCTTTGC CCGCCGGCCC TCCCTGCGGC TGCATCGCAA GACCCACCAG 
GTGCCAGCTG CCCCTGCCCC TTGCCCATGC CCTGTGTGTG GGCGGCCCCT GGCCAACCAG 
GGCTCCCTGC GGAACCATAT GAGGCTCCAT ACAGGAGAAA AGCCTTTCCT GTGCCCGCAC 
TGTGGCCGGG CGTTTCGTCA GCGGGGCAAC CTGCGTGGGC ATTTGCGGCT CCACACCGGG 
GAGCGTCCTT ACCGCTGCCC ACACTGTGCC GATGCCTTCC CCCAGCTGCC TGAACTGCGG 
CGCCATCTCA TCTCACACAC CGGGGAGGCC CACTTGTGCC CGGTGTGTGG CAAGGCCCTC 
CGAGACCCAC ACACGCTCCG AGCTCACGAG CGCCTGCACT CCGGAGAGAG GCCCTTTCCC 
TGTCCCCAGT GTGGCCGTGC TTACACGCTG GCCACCAAGC TGCGGCGCCA CCTCAAATCT 
CACTTGGAGG ACAAGCCCTA CCGCTGCCCC ACCTGTGGCA TGGGCTACAC CCTCCCGCAG 
AGCCTCAGGC GGCATCAGCT CAGTCACCGG CCTGAGGCAC CCTGCAGCCC ACCCTCTGTG 
CCTTCTGCTG CTTCTGAGCC CACTGTGGTG CTCCTGCAGG CTGAGCCACA ACTGCTGGAC 
ACACACAGAG AGGAGGAAGT CTCCCCCGCC AGGGATGTTG TTGAGGTCAC CATTTCAGAA 
AGCCAGGAGA AGTGCTTTGT GGTGCCAGAG GAGCCAGATG CCGCCCCCAG CCTGGTGCTA 
ATCCATAAGG ACATGGGCCT CGGCGCCTGG GCAGAGGTGG TGGAGGTGGA GATGGGCACC 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZNF408 ( NM_001184751.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171680.1 Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.

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CloneID	OHu04815
Clone ID Related Accession (Same CDS sequence)	NM_001184751.1 , NM_001184751.2
Accession Version	NM_001184751.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-11-03
Organism	Homo sapiens(human)
Product	zinc finger protein 408 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK302180.1, AK022889.1, BC015708.2 and AW246726.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302180.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGCGA CCCTCAACCT TGGCCCAGCC CGCGAGCCGC GCCTGGGCCT GGACTTAGGA 
TGGAACCCTT CCGGAGAAGG CTGTACGCAG GGCCTCAAAG ACGTCCCACC CGAGCCGACC 
CGAGACATCC TCGCTTTAAA GAGCCTTCCC CGGGGCTTGG CCCTTGGCCC CTCACTCGCC 
AAGGAACAGC GCTTGGGGGT CTGGTGTGTC GGGGACCCCC TGCAGCCCGG CCTGCTGTGG 
GGGCCGCTGG AAGAGGAGTC TGCCTCCAAG GAGAAGGGCG AGGGAGTAAA GCCACGGCAG 
GAGGAGAACC TGTCATTAGG CCCATGGGGA GACGTGTGTG CCTGTGAGCA GAGTTCTGGC 
TGGACTAGCT TGGTACAACG GGGCAGGCTG GAGAGTGAGG GAAATGTGGC CCCAGTGCGG 
ATCAGCGAGA GGCTTCATCT GCAAGTGTAC CAGCTGGTGC TGCCAGGCTC TGAACTGCTG 
CTGTGGCCCC AGCCTTCCTC TGAGGGCCCA AGTCTCACCC AGCCTGGGCT GGACAAAGAG 
GCAGCTGTAG CAGTGGTGAC AGAAGTGGAG TCTGCTGTAC AGCAGGAAGT GGCCTCCCCT 
GGGGAGGATG CAGCAGAACC TTGCATAGAT CCTGGTTCCC AGTCACCCTC TGGCATCCAG 
GCAGAGAATA TGGTGAGCCC TGGACTTAAG TTCCCAACCC AGGACCGAAT TTCCAAGGAT 
AGCCAGCCAC TTGGCCCATT GCTTCAGGAT GGCGACGTGG ATGAGGAATG CCCGGCCCAG 
GCACAGATGC CACCTGAACT TCAGAGCAAT TCGGCTACCC AGCAGGACCC AGATGGCAGT 
GGAGCCAGTT TCTCATCTTC TGCCAGGGGC ACCCAGCCGC ATGGCTACCT GGCCAAGAAG 
TTACACAGCC CCAGTGATCA GTGCCCACCC AGAGCAAAGA CCCCAGAGCC TGGAGCCCAG 
CAGTCTGGCT TCCCTACACT CTCGCGGAGC CCTCCTGGCC CAGCAGGAAG CTCCCCAAAG 
CAGGGGCGAC GGTACCGGTG TGGAGAGTGT GGCAAGGCAT TCCTACAGCT GTGCCACCTA 
AAGAAGCACG CATTTGTGCA CACGGGCCAC AAGCCCTTTC TTTGCACTGA GTGTGGCAAG 
AGCTATAGCT CAGAGGAGAG CTTCAAAGCC CATATGCTGG GCCACCGTGG GGTGCGGCCC 
TTCCCCTGTC CACAATGCGA CAAGGCCTAT GGCACCCAGC GAGACCTCAA AGAGCACCAG 
GTGGTACATT CAGGTGCCCG GCCCTTTGCT TGTGACCAGT GTGGCAAGGC CTTTGCCCGC 
CGGCCCTCCC TGCGGCTGCA TCGCAAGACC CACCAGGTGC CAGCTGCCCC TGCCCCTTGC 
CCATGCCCTG TGTGTGGGCG GCCCCTGGCC AACCAGGGCT CCCTGCGGAA CCATATGAGG 
CTCCATACAG GAGAAAAGCC TTTCCTGTGC CCGCACTGTG GCCGGGCGTT TCGTCAGCGG 
GGCAACCTGC GTGGGCATTT GCGGCTCCAC ACCGGGGAGC GTCCTTACCG CTGCCCACAC 
TGTGCCGATG CCTTCCCCCA GCTGCCTGAA CTGCGGCGCC ATCTCATCTC ACACACCGGG 
GAGGCCCACT TGTGCCCGGT GTGTGGCAAG GCCCTCCGAG ACCCACACAC GCTCCGAGCT 
CACGAGCGCC TGCACTCCGG AGAGAGGCCC TTTCCCTGTC CCCAGTGTGG CCGTGCTTAC 
ACGCTGGCCA CCAAGCTGCG GCGCCACCTC AAATCTCACT TGGAGGACAA GCCCTACCGC 
TGCCCCACCT GTGGCATGGG CTACACCCTC CCGCAGAGCC TCAGGCGGCA TCAGCTCAGT 
CACCGGCCTG AGGCACCCTG CAGCCCACCC TCTGTGCCTT CTGCTGCTTC TGAGCCCACT 
GTGGTGCTCC TGCAGGCTGA GCCACAACTG CTGGACACAC ACAGAGAGGA GGAAGTCTCC 
CCCGCCAGGG ATGTTGTTGA GGTCACCATT TCAGAAAGCC AGGAGAAGTG CTTTGTGGTG 
CCAGAGGAGC CAGATGCCGC CCCCAGCCTG GTGCTAATCC ATAAGGACAT GGGCCTCGGC 
GCCTGGGCAG AGGTGGTGGA GGTGGAGATG GGCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171680.1
CDS	21..2159
Translation	MSATLNLGPAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT

Target ORF information:

RefSeq Version	NM_001184751.1
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184751.1

ORF Insert Sequence:

ATGTCCGCGA CCCTCAACCT TGGCCCAGCC CGCGAGCCGC GCCTGGGCCT GGACTTAGGA 
TGGAACCCTT CCGGAGAAGG CTGTACGCAG GGCCTCAAAG ACGTCCCACC CGAGCCGACC 
CGAGACATCC TCGCTTTAAA GAGCCTTCCC CGGGGCTTGG CCCTTGGCCC CTCACTCGCC 
AAGGAACAGC GCTTGGGGGT CTGGTGTGTC GGGGACCCCC TGCAGCCCGG CCTGCTGTGG 
GGGCCGCTGG AAGAGGAGTC TGCCTCCAAG GAGAAGGGCG AGGGAGTAAA GCCACGGCAG 
GAGGAGAACC TGTCATTAGG CCCATGGGGA GACGTGTGTG CCTGTGAGCA GAGTTCTGGC 
TGGACTAGCT TGGTACAACG GGGCAGGCTG GAGAGTGAGG GAAATGTGGC CCCAGTGCGG 
ATCAGCGAGA GGCTTCATCT GCAAGTGTAC CAGCTGGTGC TGCCAGGCTC TGAACTGCTG 
CTGTGGCCCC AGCCTTCCTC TGAGGGCCCA AGTCTCACCC AGCCTGGGCT GGACAAAGAG 
GCAGCTGTAG CAGTGGTGAC AGAAGTGGAG TCTGCTGTAC AGCAGGAAGT GGCCTCCCCT 
GGGGAGGATG CAGCAGAACC TTGCATAGAT CCTGGTTCCC AGTCACCCTC TGGCATCCAG 
GCAGAGAATA TGGTGAGCCC TGGACTTAAG TTCCCAACCC AGGACCGAAT TTCCAAGGAT 
AGCCAGCCAC TTGGCCCATT GCTTCAGGAT GGCGACGTGG ATGAGGAATG CCCGGCCCAG 
GCACAGATGC CACCTGAACT TCAGAGCAAT TCGGCTACCC AGCAGGACCC AGATGGCAGT 
GGAGCCAGTT TCTCATCTTC TGCCAGGGGC ACCCAGCCGC ATGGCTACCT GGCCAAGAAG 
TTACACAGCC CCAGTGATCA GTGCCCACCC AGAGCAAAGA CCCCAGAGCC TGGAGCCCAG 
CAGTCTGGCT TCCCTACACT CTCGCGGAGC CCTCCTGGCC CAGCAGGAAG CTCCCCAAAG 
CAGGGGCGAC GGTACCGGTG TGGAGAGTGT GGCAAGGCAT TCCTACAGCT GTGCCACCTA 
AAGAAGCACG CATTTGTGCA CACGGGCCAC AAGCCCTTTC TTTGCACTGA GTGTGGCAAG 
AGCTATAGCT CAGAGGAGAG CTTCAAAGCC CATATGCTGG GCCACCGTGG GGTGCGGCCC 
TTCCCCTGTC CACAATGCGA CAAGGCCTAT GGCACCCAGC GAGACCTCAA AGAGCACCAG 
GTGGTACATT CAGGTGCCCG GCCCTTTGCT TGTGACCAGT GTGGCAAGGC CTTTGCCCGC 
CGGCCCTCCC TGCGGCTGCA TCGCAAGACC CACCAGGTGC CAGCTGCCCC TGCCCCTTGC 
CCATGCCCTG TGTGTGGGCG GCCCCTGGCC AACCAGGGCT CCCTGCGGAA CCATATGAGG 
CTCCATACAG GAGAAAAGCC TTTCCTGTGC CCGCACTGTG GCCGGGCGTT TCGTCAGCGG 
GGCAACCTGC GTGGGCATTT GCGGCTCCAC ACCGGGGAGC GTCCTTACCG CTGCCCACAC 
TGTGCCGATG CCTTCCCCCA GCTGCCTGAA CTGCGGCGCC ATCTCATCTC ACACACCGGG 
GAGGCCCACT TGTGCCCGGT GTGTGGCAAG GCCCTCCGAG ACCCACACAC GCTCCGAGCT 
CACGAGCGCC TGCACTCCGG AGAGAGGCCC TTTCCCTGTC CCCAGTGTGG CCGTGCTTAC 
ACGCTGGCCA CCAAGCTGCG GCGCCACCTC AAATCTCACT TGGAGGACAA GCCCTACCGC 
TGCCCCACCT GTGGCATGGG CTACACCCTC CCGCAGAGCC TCAGGCGGCA TCAGCTCAGT 
CACCGGCCTG AGGCACCCTG CAGCCCACCC TCTGTGCCTT CTGCTGCTTC TGAGCCCACT 
GTGGTGCTCC TGCAGGCTGA GCCACAACTG CTGGACACAC ACAGAGAGGA GGAAGTCTCC 
CCCGCCAGGG ATGTTGTTGA GGTCACCATT TCAGAAAGCC AGGAGAAGTG CTTTGTGGTG 
CCAGAGGAGC CAGATGCCGC CCCCAGCCTG GTGCTAATCC ATAAGGACAT GGGCCTCGGC 
GCCTGGGCAG AGGTGGTGGA GGTGGAGATG GGCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ZNF408 ( NM_001184751.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001171680.1 Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.

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CloneID	OHu04815
Clone ID Related Accession (Same CDS sequence)	NM_001184751.1 , NM_001184751.2
Accession Version	NM_001184751.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2139bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	zinc finger protein 408 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC115088.6, AK302180.1, AK022889.1, BC015708.2 and AW246726.1. On May 31, 2019 this sequence version replaced NM_001184751.1. Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK302180.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCGCGA CCCTCAACCT TGGCCCAGCC CGCGAGCCGC GCCTGGGCCT GGACTTAGGA 
TGGAACCCTT CCGGAGAAGG CTGTACGCAG GGCCTCAAAG ACGTCCCACC CGAGCCGACC 
CGAGACATCC TCGCTTTAAA GAGCCTTCCC CGGGGCTTGG CCCTTGGCCC CTCACTCGCC 
AAGGAACAGC GCTTGGGGGT CTGGTGTGTC GGGGACCCCC TGCAGCCCGG CCTGCTGTGG 
GGGCCGCTGG AAGAGGAGTC TGCCTCCAAG GAGAAGGGCG AGGGAGTAAA GCCACGGCAG 
GAGGAGAACC TGTCATTAGG CCCATGGGGA GACGTGTGTG CCTGTGAGCA GAGTTCTGGC 
TGGACTAGCT TGGTACAACG GGGCAGGCTG GAGAGTGAGG GAAATGTGGC CCCAGTGCGG 
ATCAGCGAGA GGCTTCATCT GCAAGTGTAC CAGCTGGTGC TGCCAGGCTC TGAACTGCTG 
CTGTGGCCCC AGCCTTCCTC TGAGGGCCCA AGTCTCACCC AGCCTGGGCT GGACAAAGAG 
GCAGCTGTAG CAGTGGTGAC AGAAGTGGAG TCTGCTGTAC AGCAGGAAGT GGCCTCCCCT 
GGGGAGGATG CAGCAGAACC TTGCATAGAT CCTGGTTCCC AGTCACCCTC TGGCATCCAG 
GCAGAGAATA TGGTGAGCCC TGGACTTAAG TTCCCAACCC AGGACCGAAT TTCCAAGGAT 
AGCCAGCCAC TTGGCCCATT GCTTCAGGAT GGCGACGTGG ATGAGGAATG CCCGGCCCAG 
GCACAGATGC CACCTGAACT TCAGAGCAAT TCGGCTACCC AGCAGGACCC AGATGGCAGT 
GGAGCCAGTT TCTCATCTTC TGCCAGGGGC ACCCAGCCGC ATGGCTACCT GGCCAAGAAG 
TTACACAGCC CCAGTGATCA GTGCCCACCC AGAGCAAAGA CCCCAGAGCC TGGAGCCCAG 
CAGTCTGGCT TCCCTACACT CTCGCGGAGC CCTCCTGGCC CAGCAGGAAG CTCCCCAAAG 
CAGGGGCGAC GGTACCGGTG TGGAGAGTGT GGCAAGGCAT TCCTACAGCT GTGCCACCTA 
AAGAAGCACG CATTTGTGCA CACGGGCCAC AAGCCCTTTC TTTGCACTGA GTGTGGCAAG 
AGCTATAGCT CAGAGGAGAG CTTCAAAGCC CATATGCTGG GCCACCGTGG GGTGCGGCCC 
TTCCCCTGTC CACAATGCGA CAAGGCCTAT GGCACCCAGC GAGACCTCAA AGAGCACCAG 
GTGGTACATT CAGGTGCCCG GCCCTTTGCT TGTGACCAGT GTGGCAAGGC CTTTGCCCGC 
CGGCCCTCCC TGCGGCTGCA TCGCAAGACC CACCAGGTGC CAGCTGCCCC TGCCCCTTGC 
CCATGCCCTG TGTGTGGGCG GCCCCTGGCC AACCAGGGCT CCCTGCGGAA CCATATGAGG 
CTCCATACAG GAGAAAAGCC TTTCCTGTGC CCGCACTGTG GCCGGGCGTT TCGTCAGCGG 
GGCAACCTGC GTGGGCATTT GCGGCTCCAC ACCGGGGAGC GTCCTTACCG CTGCCCACAC 
TGTGCCGATG CCTTCCCCCA GCTGCCTGAA CTGCGGCGCC ATCTCATCTC ACACACCGGG 
GAGGCCCACT TGTGCCCGGT GTGTGGCAAG GCCCTCCGAG ACCCACACAC GCTCCGAGCT 
CACGAGCGCC TGCACTCCGG AGAGAGGCCC TTTCCCTGTC CCCAGTGTGG CCGTGCTTAC 
ACGCTGGCCA CCAAGCTGCG GCGCCACCTC AAATCTCACT TGGAGGACAA GCCCTACCGC 
TGCCCCACCT GTGGCATGGG CTACACCCTC CCGCAGAGCC TCAGGCGGCA TCAGCTCAGT 
CACCGGCCTG AGGCACCCTG CAGCCCACCC TCTGTGCCTT CTGCTGCTTC TGAGCCCACT 
GTGGTGCTCC TGCAGGCTGA GCCACAACTG CTGGACACAC ACAGAGAGGA GGAAGTCTCC 
CCCGCCAGGG ATGTTGTTGA GGTCACCATT TCAGAAAGCC AGGAGAAGTG CTTTGTGGTG 
CCAGAGGAGC CAGATGCCGC CCCCAGCCTG GTGCTAATCC ATAAGGACAT GGGCCTCGGC 
GCCTGGGCAG AGGTGGTGGA GGTGGAGATG GGCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001171680.1
CDS	84..2222
Translation	MSATLNLGPAREPRLGLDLGWNPSGEGCTQGLKDVPPEPTRDILALKSLPRGLALGPSLAKEQRLGVWCVGDPLQPGLLWGPLEEESASKEKGEGVKPRQEENLSLGPWGDVCACEQSSGWTSLVQRGRLESEGNVAPVRISERLHLQVYQLVLPGSELLLWPQPSSEGPSLTQPGLDKEAAVAVVTEVESAVQQEVASPGEDAAEPCIDPGSQSPSGIQAENMVSPGLKFPTQDRISKDSQPLGPLLQDGDVDEECPAQAQMPPELQSNSATQQDPDGSGASFSSSARGTQPHGYLAKKLHSPSDQCPPRAKTPEPGAQQSGFPTLSRSPPGPAGSSPKQGRRYRCGECGKAFLQLCHLKKHAFVHTGHKPFLCTECGKSYSSEESFKAHMLGHRGVRPFPCPQCDKAYGTQRDLKEHQVVHSGARPFACDQCGKAFARRPSLRLHRKTHQVPAAPAPCPCPVCGRPLANQGSLRNHMRLHTGEKPFLCPHCGRAFRQRGNLRGHLRLHTGERPYRCPHCADAFPQLPELRRHLISHTGEAHLCPVCGKALRDPHTLRAHERLHSGERPFPCPQCGRAYTLATKLRRHLKSHLEDKPYRCPTCGMGYTLPQSLRRHQLSHRPEAPCSPPSVPSAASEPTVVLLQAEPQLLDTHREEEVSPARDVVEVTISESQEKCFVVPEEPDAAPSLVLIHKDMGLGAWAEVVEVEMGT

Target ORF information:

RefSeq Version	NM_001184751.2
Organism	Homo sapiens(human)
Definition	Homo sapiens zinc finger protein 408 (ZNF408), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001184751.2

ORF Insert Sequence:

ATGTCCGCGA CCCTCAACCT TGGCCCAGCC CGCGAGCCGC GCCTGGGCCT GGACTTAGGA 
TGGAACCCTT CCGGAGAAGG CTGTACGCAG GGCCTCAAAG ACGTCCCACC CGAGCCGACC 
CGAGACATCC TCGCTTTAAA GAGCCTTCCC CGGGGCTTGG CCCTTGGCCC CTCACTCGCC 
AAGGAACAGC GCTTGGGGGT CTGGTGTGTC GGGGACCCCC TGCAGCCCGG CCTGCTGTGG 
GGGCCGCTGG AAGAGGAGTC TGCCTCCAAG GAGAAGGGCG AGGGAGTAAA GCCACGGCAG 
GAGGAGAACC TGTCATTAGG CCCATGGGGA GACGTGTGTG CCTGTGAGCA GAGTTCTGGC 
TGGACTAGCT TGGTACAACG GGGCAGGCTG GAGAGTGAGG GAAATGTGGC CCCAGTGCGG 
ATCAGCGAGA GGCTTCATCT GCAAGTGTAC CAGCTGGTGC TGCCAGGCTC TGAACTGCTG 
CTGTGGCCCC AGCCTTCCTC TGAGGGCCCA AGTCTCACCC AGCCTGGGCT GGACAAAGAG 
GCAGCTGTAG CAGTGGTGAC AGAAGTGGAG TCTGCTGTAC AGCAGGAAGT GGCCTCCCCT 
GGGGAGGATG CAGCAGAACC TTGCATAGAT CCTGGTTCCC AGTCACCCTC TGGCATCCAG 
GCAGAGAATA TGGTGAGCCC TGGACTTAAG TTCCCAACCC AGGACCGAAT TTCCAAGGAT 
AGCCAGCCAC TTGGCCCATT GCTTCAGGAT GGCGACGTGG ATGAGGAATG CCCGGCCCAG 
GCACAGATGC CACCTGAACT TCAGAGCAAT TCGGCTACCC AGCAGGACCC AGATGGCAGT 
GGAGCCAGTT TCTCATCTTC TGCCAGGGGC ACCCAGCCGC ATGGCTACCT GGCCAAGAAG 
TTACACAGCC CCAGTGATCA GTGCCCACCC AGAGCAAAGA CCCCAGAGCC TGGAGCCCAG 
CAGTCTGGCT TCCCTACACT CTCGCGGAGC CCTCCTGGCC CAGCAGGAAG CTCCCCAAAG 
CAGGGGCGAC GGTACCGGTG TGGAGAGTGT GGCAAGGCAT TCCTACAGCT GTGCCACCTA 
AAGAAGCACG CATTTGTGCA CACGGGCCAC AAGCCCTTTC TTTGCACTGA GTGTGGCAAG 
AGCTATAGCT CAGAGGAGAG CTTCAAAGCC CATATGCTGG GCCACCGTGG GGTGCGGCCC 
TTCCCCTGTC CACAATGCGA CAAGGCCTAT GGCACCCAGC GAGACCTCAA AGAGCACCAG 
GTGGTACATT CAGGTGCCCG GCCCTTTGCT TGTGACCAGT GTGGCAAGGC CTTTGCCCGC 
CGGCCCTCCC TGCGGCTGCA TCGCAAGACC CACCAGGTGC CAGCTGCCCC TGCCCCTTGC 
CCATGCCCTG TGTGTGGGCG GCCCCTGGCC AACCAGGGCT CCCTGCGGAA CCATATGAGG 
CTCCATACAG GAGAAAAGCC TTTCCTGTGC CCGCACTGTG GCCGGGCGTT TCGTCAGCGG 
GGCAACCTGC GTGGGCATTT GCGGCTCCAC ACCGGGGAGC GTCCTTACCG CTGCCCACAC 
TGTGCCGATG CCTTCCCCCA GCTGCCTGAA CTGCGGCGCC ATCTCATCTC ACACACCGGG 
GAGGCCCACT TGTGCCCGGT GTGTGGCAAG GCCCTCCGAG ACCCACACAC GCTCCGAGCT 
CACGAGCGCC TGCACTCCGG AGAGAGGCCC TTTCCCTGTC CCCAGTGTGG CCGTGCTTAC 
ACGCTGGCCA CCAAGCTGCG GCGCCACCTC AAATCTCACT TGGAGGACAA GCCCTACCGC 
TGCCCCACCT GTGGCATGGG CTACACCCTC CCGCAGAGCC TCAGGCGGCA TCAGCTCAGT 
CACCGGCCTG AGGCACCCTG CAGCCCACCC TCTGTGCCTT CTGCTGCTTC TGAGCCCACT 
GTGGTGCTCC TGCAGGCTGA GCCACAACTG CTGGACACAC ACAGAGAGGA GGAAGTCTCC 
CCCGCCAGGG ATGTTGTTGA GGTCACCATT TCAGAAAGCC AGGAGAAGTG CTTTGTGGTG 
CCAGAGGAGC CAGATGCCGC CCCCAGCCTG GTGCTAATCC ATAAGGACAT GGGCCTCGGC 
GCCTGGGCAG AGGTGGTGGA GGTGGAGATG GGCACCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Exome sequencing confirms ZNF408 mutations as a cause of familial retinitis pigmentosa.
Ophthalmic genetics38(5)494-497(2017 Sep-Oct)
Habibi I,Chebil A,Kort F,Schorderet DF,El Matri L

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

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ZNF408 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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