The following ZNF74 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ZNF74 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu07669 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256525.2 , NM_001256525.1 | |
| Accession Version | NM_001256525.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1722bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-27 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform c | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC048295.1, BC013395.2, AC007731.16 and BG912037.1. On May 31, 2019 this sequence version replaced NM_001256525.1. Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.149113.1, BC048295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTTGGAGA ACTACCAGAA CCTTCTTGCC CTAGGACCTC CACTGCACAA GCCAGATGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243454.1 |
| CDS | 364..2085 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001256525.2 |
1 | ATGTTGGAGA ACTACCAGAA CCTTCTTGCC CTAGGACCTC CACTGCACAA GCCAGATGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu07669 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256525.2 , NM_001256525.1 | |
| Accession Version | NM_001256525.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1722bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-23 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform c | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC048295.1, BC013395.2, AC007731.16 and BG912037.1. Transcript Variant: This variant (4) differs in the 5' UTR, lacks a portion of the 5' coding region, and uses a downstream in-frame start codon, compared to variant 1. The encoded isoform (c) is shorter at the N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.149113.1, BC048295.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTTGGAGA ACTACCAGAA CCTTCTTGCC CTAGGACCTC CACTGCACAA GCCAGATGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243454.1 |
| CDS | 400..2121 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001256525.1 |
1 | ATGTTGGAGA ACTACCAGAA CCTTCTTGCC CTAGGACCTC CACTGCACAA GCCAGATGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08045 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256524.1 , NM_003426.3 , NM_003426.4 | |
| Accession Version | NM_001256524.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-20 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, AK291358.1, BC056902.1, BC013395.2, AC007731.16 and BG912037.1. Transcript Variant: This variant (3) lacks an alternate segment in the 5' UTR, compared to variant 1. Both variants 1 and 3 encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK291358.1, DC374105.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2150585, SAMEA2161674 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243453.1 |
| CDS | 287..2221 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001256524.1 |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08045 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256524.1 , NM_003426.3 , NM_003426.4 | |
| Accession Version | NM_003426.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-02 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC013395.2, BC056902.1, AC007731.16 and BG912037.1. On Feb 3, 2012 this sequence version replaced NM_003426.2. Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 3 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.86723.1, SRR1803612.113983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_003417.2 |
| CDS | 515..2449 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_003426.3 |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu08045 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001256524.1 , NM_003426.3 , NM_003426.4 | |
| Accession Version | NM_003426.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1935bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-26 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC013395.2, BC056902.1, AC007731.16 and BG912037.1. On Nov 23, 2018 this sequence version replaced NM_003426.3. Transcript Variant: This variant (1) encodes the longest isoform (a). Both variants 1 and 3 encode isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.86723.1, SRR1803612.113983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000400451.7/ ENSP00000383301.2 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_003417.2 |
| CDS | 479..2413 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_003426.4 |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGCTCTTT CCTCTCAGGA TCCTGCTCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu12134 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001256523.1 , NM_001256523.2 | |
| Accession Version | NM_001256523.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-24 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC013741.1, BC013395.2, AC007731.16 and BG912037.1. On Feb 4, 2012 this sequence version replaced NR_003253.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, resulting in a frameshift in the remaining coding region, compared to variant 1. The encoded isoform (b) shares the same N-terminus but is otherwise distinct and shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.24975.1, SRR1803616.8576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGGAATCG GTGAGTTTCA AGGATGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243452.1 |
| CDS | 515..1051 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001256523.1 |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGGAATCG GTGAGTTTCA AGGATGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu12134 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001256523.1 , NM_001256523.2 | |
| Accession Version | NM_001256523.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 537bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-27 | |
| Organism | Homo sapiens(human) | |
| Product | zinc finger protein 74 isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA791304.1, BC013741.1, BC013395.2, AC007731.16 and BG912037.1. On May 31, 2019 this sequence version replaced NM_001256523.1. Transcript Variant: This variant (2) lacks an alternate exon in the 5' coding region, resulting in a frameshift in the remaining coding region, compared to variant 1. The encoded isoform (b) shares the same N-terminus but is otherwise distinct and shorter, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.24975.1, SRR1803616.8576.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGGAATCG GTGAGTTTCA AGGATGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001243452.1 |
| CDS | 479..1015 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001256523.2 |
1 | ATGGAGATCC CTGCCCCGGA GCCCGAGAAG ACAGGAATCG GTGAGTTTCA AGGATGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Oligomerization of transcriptional intermediary factor 1 regulators and interaction with ZNF74 nuclear matrix protein revealed by bioluminescence resonance energy transfer in living cells. |
Association of ZNF74 gene genotypes with age-at-onset of schizophrenia. |
Alternative promoter usage and splicing of ZNF74 multifinger gene produce protein isoforms with a different repressor activity and nuclear partitioning. |
ZNF74, a gene deleted in DiGeorge syndrome, is expressed in human neural crest-derived tissues and foregut endoderm epithelia. |
Direct interaction of the KRAB/Cys2-His2 zinc finger protein ZNF74 with a hyperphosphorylated form of the RNA polymerase II largest subunit. |
