Gene Symbol | YWHAZ |
Entrez Gene ID | 7534 |
Full Name | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta |
Synonyms | 14-3-3-zeta,HEL-S-3,HEL-S-93,HEL4,KCIP-1,YWHAD |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and sheep orthologs. The encoded protein interacts with IRS1 protein, suggesting a role in regulating insulin sensitivity. Several transcript variants that differ in the 5' UTR but that encode the same protein have been identified for this gene. [provided by RefSeq, Oct 2008]. |
Disorder MIM: |