| Gene Symbol | XRCC3 |
| Entrez Gene ID | 7517 |
| Full Name | X-ray repair cross complementing 3 |
| Synonyms | CMM6 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(Human) |
| Genome | |
| Summary | This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]. |
| Disorder MIM: | |
| Disorder Html: | {Melanoma, cutaneous malignant, 6}, 613972 (3); {Breast cancer, susceptibility to}, 114480 (3) |








































User Manual