XDH cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	XDH
Entrez Gene ID	7498
Full Name	xanthine dehydrogenase
Synonyms	XAN1,XO,XOR
General protein information	Preferred Names xanthine dehydrogenase Names xanthine dehydrogenase/oxidase xanthine oxidoreductase
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2p23.1
Summary	Xanthine dehydrogenase belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Xanthine dehydrogenase can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism. [provided by RefSeq, Jan 2014].
Disorder MIM:	607633
Disorder Html:	Xanthinuria, type I, 278300 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_000379.4	NP_000370.2	xanthine dehydrogenase/oxidase
XM_011533095.2	XP_011531397.1	xanthine dehydrogenase/oxidase isoform X1
XM_011533096.2	XP_011531398.1	xanthine dehydrogenase/oxidase isoform X2
NM_000379.3	NP_000370.2	xanthine dehydrogenase/oxidase

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	XDH	XP_525729.2
Canis lupus familiaris (dog)	XDH	XP_540143.2
Bos taurus (cattle)	XDH	NP_776397.1
Gallus gallus (chicken)	XDH	NP_990458.1
Drosophila melanogaster (fruit fly)	ry	NP_524337.1
Arabidopsis thaliana (thale cress)	XDH1	NP_195215.2
Oryza sativa (rice)	Os03g0429800	NP_001050420.1
Homo sapiens (human)	XDH	NP_000370.2
Danio rerio (zebrafish)	xdh	XP_688983.3
Caenorhabditis elegans (roundworm)	F55B11.1	NP_502747.1
Arabidopsis thaliana (thale cress)	XDH2	NP_195216.2
Magnaporthe oryzae (rice blast fungus)	MGG_12738	XP_003716708.1
Neurospora crassa	NCU03350	XP_956459.2
Rattus norvegicus (Norway rat)	Xdh	NP_058850.1
Xenopus tropicalis (tropical clawed frog)	LOC100497499	XP_004914866.1
	XDH	XP_002808080.1
Mus musculus (house mouse)	Xdh	NP_035853.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP007918	XP_317568.3

Gene Ontology
Bibliography

Related articles in PubMed

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.
Huff RD, Hsu AC, Nichol KS, Jones B, Knight DA, Wark PAB, Hansbro PM, Hirota JA
PloS one12(9)e0184260(2017)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

data suggest that Alcohol use disorders augment pulmonary and systemic XOR activity that may contribute to ROS and uric acid generation, promoting inflammation.
Title: Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity.

XOR activity is correlated with insulin resistance, BMI, and subclinical inflammation.
Title: Xanthine oxidoreductase activity is correlated with insulin resistance and subclinical inflammation in young humans.

Study showed that DKK3 promotes cell survival during oxidative stress by suppressing XDH expression, thereby abrogating excess reactive oxygen species accumulation and subsequent apoptosis.
Title: Dickkopf 3 attenuates xanthine dehydrogenase expression to prevent oxidative stress-induced apoptosis.

xanthine dehydrogensase gene expression and uric acid production is altered in asthma and in human airway epithelial cells
Title: Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.

Among cardiac patients, left ventricular hypertrophy, low LVEF, and increased BNP were significantly associated with plasma XOR activity independent of various confounding factors.
Title: Relationship between plasma xanthine oxidoreductase activity and left ventricular ejection fraction and hypertrophy among cardiac patients.

The following XDH gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XDH cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu61341	XM_011533095.2 Latest version!	Homo sapiens xanthine dehydrogenase (XDH), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$643.30 $919.00
OHu61342	XM_011533096.2 Latest version!	Homo sapiens xanthine dehydrogenase (XDH), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00
OHu22572	NM_000379.4 Latest version!	Homo sapiens xanthine dehydrogenase (XDH), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
View Old Accession Versions >>
OHu22572	NM_000379.3	Homo sapiens xanthine dehydrogenase (XDH), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$923.30 $1319.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

XDH ( XM_011533095.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531397.1 Homo sapiens xanthine dehydrogenase (XDH), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu61341
Clone ID Related Accession (Same CDS sequence)	XM_011533095.2
Accession Version	XM_011533095.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3999bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	xanthine dehydrogenase/oxidase isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533095.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACTGTGGTAA ACTGGACCCC 
ACTTTCGCCA GTGCAACTTT ACTGTTTCAG AAAGACCCCC CAGCCGATGT CCAGCTCTTC 
CAAGAGGTGC CCAAGGGTCA GTCTGAGGAG GACATGGTGG GCCGGCCCCT GCCCCACCTG 
GCAGCGGACA TGCAGGCCTC TGGTGAGGCC GTGTACTGTG ACGACATTCC TCGCTACGAG 
AATGAGCTGT CTCTCCGGCT GGTCACCAGC ACCCGGGCCC ACGCCAAGAT CAAGTCCATA 
GATACATCAG AAGCTAAGAA GGTTCCAGGG TTTGTTTGTT TCATTTCCGC TGATGATGTT 
CCTGGGAGTA ACATAACTGG AATTTGTAAT GATGAGACAG TCTTTGCGAA GGATAAGGTT 
ACTTGTGTTG GGCATATCAT TGGTGCTGTG GTTGCTGACA CCCCGGAACA CACACAGAGA 
GCTGCCCAAG GGGTGAAAAT CACCTATGAA GAACTACCAG CCATTATCAC AATTGAGGAT 
GCTATAAAGA ACAACTCCTT TTATGGACCT GAGCTGAAGA TCGAGAAAGG GGACCTAAAG 
AAGGGGTTTT CCGAAGCAGA TAATGTTGTG TCAGGGGAGA TATACATCGG TGGCCAAGAG 
CACTTCTACC TGGAGACTCA CTGCACCATT GCTGTTCCAA AAGGCGAGGC AGGGGAGATG 
GAGCTCTTTG TGTCTACACA GAACACCATG AAGACCCAGA GCTTTGTTGC AAAAATGTTG 
GGGGTTCCAG CAAACCGGAT TGTGGTTCGA GTGAAGAGAA TGGGAGGAGG CTTTGGAGGC 
AAGGAGACCC GGAGCACTGT GGTGTCCACG GCAGTGGCCC TGGCTGCATA TAAGACCGGC 
CGCCCTGTGC GATGCATGCT GGACCGTGAT GAGGACATGC TGATAACTGG TGGCAGACAT 
CCCTTCCTGG CCAGATACAA GGTTGGCTTC ATGAAGACTG GGACAGTTGT GGCTCTTGAG 
GTGGACCACT TCAGCAATGT GGGGAACACC CAGGATCTCT CTCAGAGTAT TATGGAACGA 
GCTTTATTCC ACATGGACAA CTGCTATAAA ATCCCCAACA TCCGGGGCAC TGGGCGGCTG 
TGCAAAACCA ACCTTCCCTC CAACACGGCC TTCCGGGGCT TTGGGGGGCC CCAGGGGATG 
CTCATTGCCG AGTGCTGGAT GAGTGAAGTT GCAGTGACCT GTGGGATGCC TGCAGAGGAG 
GTGCGGAGAA AAAACCTGTA CAAAGAAGGG GACCTGACAC ACTTCAACCA GAAGCTTGAG 
GGTTTCACCT TGCCCAGATG CTGGGAAGAA TGCCTAGCAA GCTCTCAGTA TCATGCTCGG 
AAGAGTGAGG TTGACAAGTT CAACAAGGAG AATTGTTGGA AAAAGAGAGG ATTGTGCATA 
ATTCCCACCA AGTTTGGAAT AAGCTTTACA GTTCCTTTTC TGAATCAGGC AGGAGCCCTA 
CTTCATGTGT ACACAGATGG CTCTGTGCTG CTGACCCACG GGGGGACTGA GATGGGCCAA 
GGCCTTCATA CCAAAATGGT CCAGGTGGCC AGTAGAGCTC TGAAAATCCC CACCTCTAAG 
ATTTATATCA GCGAGACAAG CACTAACACT GTGCCCAACA CCTCTCCCAC GGCTGCCTCT 
GTCAGCGCTG ACCTCAATGG ACAGGCCGTC TATGCGGCTT GTCAGACCAT CTTGAAAAGG 
CTGGAACCCT ACAAGAAGAA GAATCCCAGT GGCTCCTGGG AAGACTGGGT CACAGCTGCC 
TACATGGACA CAGTGAGCTT GTCTGCCACT GGGTTTTATA GAACACCCAA TCTGGGCTAC 
AGCTTTGAGA CTAACTCAGG GAACCCCTTC CACTACTTCA GCTATGGGGT GGCTTGCTCT 
GAAGTAGAAA TCGACTGCCT AACAGGAGAT CATAAGAACC TCCGCACAGA TATTGTCATG 
GATGTTGGCT CCAGTCTAAA CCCTGCCATT GATATTGGAC AGGTGGAAGG GGCATTTGTC 
CAGGGCCTTG GCCTCTTCAC CCTAGAGGAG CTACACTATT CCCCCGAGGG GAGCCTGCAC 
ACCCGTGGCC CTAGCACCTA CAAGATCCCG GCATTTGGCA GCATCCCCAT TGAGTTCAGG 
GTGTCCCTGC TCCGCGACTG CCCCAACAAG AAGGCCATCT ATGCATCGAA GGCTGTTGGA 
GAGCCGCCCC TCTTCCTGGC TGCTTCTATC TTCTTTGCCA TCAAAGATGC CATCCGTGCA 
GCTCGAGCTC AGCACACAGG TAATAACGTG AAGGAACTCT TCCGGCTAGA CAGCCCTGCC 
ACCCCGGAGA AGATCCGCAA TGCCTGCGTG GACAAGTTCA CCACCCTGTG TGTCACTGGT 
GTCCCAGAAA ACTGCAAACC CTGGTCTGTG AGGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531397.1
CDS	112..4110
Translation	MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV

Target ORF information:

RefSeq Version	XM_011533095.2
Organism	Homo sapiens(human)
Definition	Homo sapiens xanthine dehydrogenase (XDH), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011533095.2

ORF Insert Sequence:

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACTGTGGTAA ACTGGACCCC 
ACTTTCGCCA GTGCAACTTT ACTGTTTCAG AAAGACCCCC CAGCCGATGT CCAGCTCTTC 
CAAGAGGTGC CCAAGGGTCA GTCTGAGGAG GACATGGTGG GCCGGCCCCT GCCCCACCTG 
GCAGCGGACA TGCAGGCCTC TGGTGAGGCC GTGTACTGTG ACGACATTCC TCGCTACGAG 
AATGAGCTGT CTCTCCGGCT GGTCACCAGC ACCCGGGCCC ACGCCAAGAT CAAGTCCATA 
GATACATCAG AAGCTAAGAA GGTTCCAGGG TTTGTTTGTT TCATTTCCGC TGATGATGTT 
CCTGGGAGTA ACATAACTGG AATTTGTAAT GATGAGACAG TCTTTGCGAA GGATAAGGTT 
ACTTGTGTTG GGCATATCAT TGGTGCTGTG GTTGCTGACA CCCCGGAACA CACACAGAGA 
GCTGCCCAAG GGGTGAAAAT CACCTATGAA GAACTACCAG CCATTATCAC AATTGAGGAT 
GCTATAAAGA ACAACTCCTT TTATGGACCT GAGCTGAAGA TCGAGAAAGG GGACCTAAAG 
AAGGGGTTTT CCGAAGCAGA TAATGTTGTG TCAGGGGAGA TATACATCGG TGGCCAAGAG 
CACTTCTACC TGGAGACTCA CTGCACCATT GCTGTTCCAA AAGGCGAGGC AGGGGAGATG 
GAGCTCTTTG TGTCTACACA GAACACCATG AAGACCCAGA GCTTTGTTGC AAAAATGTTG 
GGGGTTCCAG CAAACCGGAT TGTGGTTCGA GTGAAGAGAA TGGGAGGAGG CTTTGGAGGC 
AAGGAGACCC GGAGCACTGT GGTGTCCACG GCAGTGGCCC TGGCTGCATA TAAGACCGGC 
CGCCCTGTGC GATGCATGCT GGACCGTGAT GAGGACATGC TGATAACTGG TGGCAGACAT 
CCCTTCCTGG CCAGATACAA GGTTGGCTTC ATGAAGACTG GGACAGTTGT GGCTCTTGAG 
GTGGACCACT TCAGCAATGT GGGGAACACC CAGGATCTCT CTCAGAGTAT TATGGAACGA 
GCTTTATTCC ACATGGACAA CTGCTATAAA ATCCCCAACA TCCGGGGCAC TGGGCGGCTG 
TGCAAAACCA ACCTTCCCTC CAACACGGCC TTCCGGGGCT TTGGGGGGCC CCAGGGGATG 
CTCATTGCCG AGTGCTGGAT GAGTGAAGTT GCAGTGACCT GTGGGATGCC TGCAGAGGAG 
GTGCGGAGAA AAAACCTGTA CAAAGAAGGG GACCTGACAC ACTTCAACCA GAAGCTTGAG 
GGTTTCACCT TGCCCAGATG CTGGGAAGAA TGCCTAGCAA GCTCTCAGTA TCATGCTCGG 
AAGAGTGAGG TTGACAAGTT CAACAAGGAG AATTGTTGGA AAAAGAGAGG ATTGTGCATA 
ATTCCCACCA AGTTTGGAAT AAGCTTTACA GTTCCTTTTC TGAATCAGGC AGGAGCCCTA 
CTTCATGTGT ACACAGATGG CTCTGTGCTG CTGACCCACG GGGGGACTGA GATGGGCCAA 
GGCCTTCATA CCAAAATGGT CCAGGTGGCC AGTAGAGCTC TGAAAATCCC CACCTCTAAG 
ATTTATATCA GCGAGACAAG CACTAACACT GTGCCCAACA CCTCTCCCAC GGCTGCCTCT 
GTCAGCGCTG ACCTCAATGG ACAGGCCGTC TATGCGGCTT GTCAGACCAT CTTGAAAAGG 
CTGGAACCCT ACAAGAAGAA GAATCCCAGT GGCTCCTGGG AAGACTGGGT CACAGCTGCC 
TACATGGACA CAGTGAGCTT GTCTGCCACT GGGTTTTATA GAACACCCAA TCTGGGCTAC 
AGCTTTGAGA CTAACTCAGG GAACCCCTTC CACTACTTCA GCTATGGGGT GGCTTGCTCT 
GAAGTAGAAA TCGACTGCCT AACAGGAGAT CATAAGAACC TCCGCACAGA TATTGTCATG 
GATGTTGGCT CCAGTCTAAA CCCTGCCATT GATATTGGAC AGGTGGAAGG GGCATTTGTC 
CAGGGCCTTG GCCTCTTCAC CCTAGAGGAG CTACACTATT CCCCCGAGGG GAGCCTGCAC 
ACCCGTGGCC CTAGCACCTA CAAGATCCCG GCATTTGGCA GCATCCCCAT TGAGTTCAGG 
GTGTCCCTGC TCCGCGACTG CCCCAACAAG AAGGCCATCT ATGCATCGAA GGCTGTTGGA 
GAGCCGCCCC TCTTCCTGGC TGCTTCTATC TTCTTTGCCA TCAAAGATGC CATCCGTGCA 
GCTCGAGCTC AGCACACAGG TAATAACGTG AAGGAACTCT TCCGGCTAGA CAGCCCTGCC 
ACCCCGGAGA AGATCCGCAA TGCCTGCGTG GACAAGTTCA CCACCCTGTG TGTCACTGGT 
GTCCCAGAAA ACTGCAAACC CTGGTCTGTG AGGGTCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XDH ( XM_011533096.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_011531398.1 Homo sapiens xanthine dehydrogenase (XDH), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OHu61342
Clone ID Related Accession (Same CDS sequence)	XM_011533096.2
Accession Version	XM_011533096.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3162bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	xanthine dehydrogenase/oxidase isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011533096.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGAG TTGGCCAGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011531398.1
CDS	111..3272
Translation	MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQELAR

Target ORF information:

RefSeq Version	XM_011533096.2
Organism	Homo sapiens(human)
Definition	Homo sapiens xanthine dehydrogenase (XDH), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011533096.2

ORF Insert Sequence:

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGAG TTGGCCAGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XDH ( NM_000379.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000370.2 Homo sapiens xanthine dehydrogenase (XDH), mRNA.

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CloneID	OHu22572
Clone ID Related Accession (Same CDS sequence)	NM_000379.4 , NM_000379.3
Accession Version	NM_000379.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	xanthine dehydrogenase/oxidase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121654.1, D11456.2, AL121657.4 and CV574002.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_000379.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.110572.1, SRR1803615.229312.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379416.4/ ENSP00000368727.3 multifunctional gene product(s) :: PMID: 17301077 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGTG GCCAGTAGAG CTCTGAAAAT CCCCACCTCT 
AAGATTTATA TCAGCGAGAC AAGCACTAAC ACTGTGCCCA ACACCTCTCC CACGGCTGCC 
TCTGTCAGCG CTGACCTCAA TGGACAGGCC GTCTATGCGG CTTGTCAGAC CATCTTGAAA 
AGGCTGGAAC CCTACAAGAA GAAGAATCCC AGTGGCTCCT GGGAAGACTG GGTCACAGCT 
GCCTACATGG ACACAGTGAG CTTGTCTGCC ACTGGGTTTT ATAGAACACC CAATCTGGGC 
TACAGCTTTG AGACTAACTC AGGGAACCCC TTCCACTACT TCAGCTATGG GGTGGCTTGC 
TCTGAAGTAG AAATCGACTG CCTAACAGGA GATCATAAGA ACCTCCGCAC AGATATTGTC 
ATGGATGTTG GCTCCAGTCT AAACCCTGCC ATTGATATTG GACAGGTGGA AGGGGCATTT 
GTCCAGGGCC TTGGCCTCTT CACCCTAGAG GAGCTACACT ATTCCCCCGA GGGGAGCCTG 
CACACCCGTG GCCCTAGCAC CTACAAGATC CCGGCATTTG GCAGCATCCC CATTGAGTTC 
AGGGTGTCCC TGCTCCGCGA CTGCCCCAAC AAGAAGGCCA TCTATGCATC GAAGGCTGTT 
GGAGAGCCGC CCCTCTTCCT GGCTGCTTCT ATCTTCTTTG CCATCAAAGA TGCCATCCGT 
GCAGCTCGAG CTCAGCACAC AGGTAATAAC GTGAAGGAAC TCTTCCGGCT AGACAGCCCT 
GCCACCCCGG AGAAGATCCG CAATGCCTGC GTGGACAAGT TCACCACCCT GTGTGTCACT 
GGTGTCCCAG AAAACTGCAA ACCCTGGTCT GTGAGGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000370.2
CDS	77..4078
Translation	MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV

Target ORF information:

RefSeq Version	NM_000379.4
Organism	Homo sapiens(human)
Definition	Homo sapiens xanthine dehydrogenase (XDH), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000379.4

ORF Insert Sequence:

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGTG GCCAGTAGAG CTCTGAAAAT CCCCACCTCT 
AAGATTTATA TCAGCGAGAC AAGCACTAAC ACTGTGCCCA ACACCTCTCC CACGGCTGCC 
TCTGTCAGCG CTGACCTCAA TGGACAGGCC GTCTATGCGG CTTGTCAGAC CATCTTGAAA 
AGGCTGGAAC CCTACAAGAA GAAGAATCCC AGTGGCTCCT GGGAAGACTG GGTCACAGCT 
GCCTACATGG ACACAGTGAG CTTGTCTGCC ACTGGGTTTT ATAGAACACC CAATCTGGGC 
TACAGCTTTG AGACTAACTC AGGGAACCCC TTCCACTACT TCAGCTATGG GGTGGCTTGC 
TCTGAAGTAG AAATCGACTG CCTAACAGGA GATCATAAGA ACCTCCGCAC AGATATTGTC 
ATGGATGTTG GCTCCAGTCT AAACCCTGCC ATTGATATTG GACAGGTGGA AGGGGCATTT 
GTCCAGGGCC TTGGCCTCTT CACCCTAGAG GAGCTACACT ATTCCCCCGA GGGGAGCCTG 
CACACCCGTG GCCCTAGCAC CTACAAGATC CCGGCATTTG GCAGCATCCC CATTGAGTTC 
AGGGTGTCCC TGCTCCGCGA CTGCCCCAAC AAGAAGGCCA TCTATGCATC GAAGGCTGTT 
GGAGAGCCGC CCCTCTTCCT GGCTGCTTCT ATCTTCTTTG CCATCAAAGA TGCCATCCGT 
GCAGCTCGAG CTCAGCACAC AGGTAATAAC GTGAAGGAAC TCTTCCGGCT AGACAGCCCT 
GCCACCCCGG AGAAGATCCG CAATGCCTGC GTGGACAAGT TCACCACCCT GTGTGTCACT 
GGTGTCCCAG AAAACTGCAA ACCCTGGTCT GTGAGGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

XDH ( NM_000379.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000370.2 Homo sapiens xanthine dehydrogenase (XDH), mRNA.

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CloneID	OHu22572
Clone ID Related Accession (Same CDS sequence)	NM_000379.4 , NM_000379.3
Accession Version	NM_000379.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4002bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	xanthine dehydrogenase/oxidase
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL121654.1, D11456.2, AL121657.4 and CV574002.1. This sequence is a reference standard in the RefSeqGene project. On Apr 11, 2006 this sequence version replaced NM_000379.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.110572.1, SRR1803615.229312.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1966682, SAMEA1968189 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## multifunctional gene product(s) :: PMID: 17301077 ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGTG GCCAGTAGAG CTCTGAAAAT CCCCACCTCT 
AAGATTTATA TCAGCGAGAC AAGCACTAAC ACTGTGCCCA ACACCTCTCC CACGGCTGCC 
TCTGTCAGCG CTGACCTCAA TGGACAGGCC GTCTATGCGG CTTGTCAGAC CATCTTGAAA 
AGGCTGGAAC CCTACAAGAA GAAGAATCCC AGTGGCTCCT GGGAAGACTG GGTCACAGCT 
GCCTACATGG ACACAGTGAG CTTGTCTGCC ACTGGGTTTT ATAGAACACC CAATCTGGGC 
TACAGCTTTG AGACTAACTC AGGGAACCCC TTCCACTACT TCAGCTATGG GGTGGCTTGC 
TCTGAAGTAG AAATCGACTG CCTAACAGGA GATCATAAGA ACCTCCGCAC AGATATTGTC 
ATGGATGTTG GCTCCAGTCT AAACCCTGCC ATTGATATTG GACAGGTGGA AGGGGCATTT 
GTCCAGGGCC TTGGCCTCTT CACCCTAGAG GAGCTACACT ATTCCCCCGA GGGGAGCCTG 
CACACCCGTG GCCCTAGCAC CTACAAGATC CCGGCATTTG GCAGCATCCC CATTGAGTTC 
AGGGTGTCCC TGCTCCGCGA CTGCCCCAAC AAGAAGGCCA TCTATGCATC GAAGGCTGTT 
GGAGAGCCGC CCCTCTTCCT GGCTGCTTCT ATCTTCTTTG CCATCAAAGA TGCCATCCGT 
GCAGCTCGAG CTCAGCACAC AGGTAATAAC GTGAAGGAAC TCTTCCGGCT AGACAGCCCT 
GCCACCCCGG AGAAGATCCG CAATGCCTGC GTGGACAAGT TCACCACCCT GTGTGTCACT 
GGTGTCCCAG AAAACTGCAA ACCCTGGTCT GTGAGGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000370.2
CDS	80..4081
Translation	MTADKLVFFVNGRKVVEKNADPETTLLAYLRRKLGLSGTKLGCGEGGCGACTVMLSKYDRLQNKIVHFSANACLAPICSLHHVAVTTVEGIGSTKTRLHPVQERIAKSHGSQCGFCTPGIVMSMYTLLRNQPEPTMEEIENAFQGNLCRCTGYRPILQGFRTFARDGGCCGGDGNNPNCCMNQKKDHSVSLSPSLFKPEEFTPLDPTQEPIFPPELLRLKDTPRKQLRFEGERVTWIQASTLKELLDLKAQHPDAKLVVGNTEIGIEMKFKNMLFPMIVCPAWIPELNSVEHGPDGISFGAACPLSIVEKTLVDAVAKLPAQKTEVFRGVLEQLRWFAGKQVKSVASVGGNIITASPISDLNPVFMASGAKLTLVSRGTRRTVQMDHTFFPGYRKTLLSPEEILLSIEIPYSREGEYFSAFKQASRREDDIAKVTSGMRVLFKPGTTEVQELALCYGGMANRTISALKTTQRQLSKLWKEELLQDVCAGLAEELHLPPDAPGGMVDFRCTLTLSFFFKFYLTVLQKLGQENLEDKCGKLDPTFASATLLFQKDPPADVQLFQEVPKGQSEEDMVGRPLPHLAADMQASGEAVYCDDIPRYENELSLRLVTSTRAHAKIKSIDTSEAKKVPGFVCFISADDVPGSNITGICNDETVFAKDKVTCVGHIIGAVVADTPEHTQRAAQGVKITYEELPAIITIEDAIKNNSFYGPELKIEKGDLKKGFSEADNVVSGEIYIGGQEHFYLETHCTIAVPKGEAGEMELFVSTQNTMKTQSFVAKMLGVPANRIVVRVKRMGGGFGGKETRSTVVSTAVALAAYKTGRPVRCMLDRDEDMLITGGRHPFLARYKVGFMKTGTVVALEVDHFSNVGNTQDLSQSIMERALFHMDNCYKIPNIRGTGRLCKTNLPSNTAFRGFGGPQGMLIAECWMSEVAVTCGMPAEEVRRKNLYKEGDLTHFNQKLEGFTLPRCWEECLASSQYHARKSEVDKFNKENCWKKRGLCIIPTKFGISFTVPFLNQAGALLHVYTDGSVLLTHGGTEMGQGLHTKMVQVASRALKIPTSKIYISETSTNTVPNTSPTAASVSADLNGQAVYAACQTILKRLEPYKKKNPSGSWEDWVTAAYMDTVSLSATGFYRTPNLGYSFETNSGNPFHYFSYGVACSEVEIDCLTGDHKNLRTDIVMDVGSSLNPAIDIGQVEGAFVQGLGLFTLEELHYSPEGSLHTRGPSTYKIPAFGSIPIEFRVSLLRDCPNKKAIYASKAVGEPPLFLAASIFFAIKDAIRAARAQHTGNNVKELFRLDSPATPEKIRNACVDKFTTLCVTGVPENCKPWSVRV

Target ORF information:

RefSeq Version	NM_000379.3
Organism	Homo sapiens(human)
Definition	Homo sapiens xanthine dehydrogenase (XDH), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000379.3

ORF Insert Sequence:

ATGACAGCAG ACAAATTGGT TTTCTTTGTG AATGGCAGAA AGGTGGTGGA GAAAAATGCA 
GATCCAGAGA CAACCCTTTT GGCCTACCTG AGAAGAAAGT TGGGGCTGAG TGGAACCAAG 
CTCGGCTGTG GAGAGGGGGG CTGCGGGGCT TGCACAGTGA TGCTCTCCAA GTATGATCGT 
CTGCAGAACA AGATCGTCCA CTTTTCTGCC AATGCCTGCC TGGCCCCCAT CTGCTCCTTG 
CACCATGTTG CAGTGACAAC TGTGGAAGGA ATAGGAAGCA CCAAGACGAG GCTGCATCCT 
GTGCAGGAGA GAATTGCCAA AAGCCACGGC TCCCAGTGCG GGTTCTGCAC CCCTGGCATC 
GTCATGAGTA TGTACACACT GCTCCGGAAT CAGCCCGAGC CCACCATGGA GGAGATTGAG 
AATGCCTTCC AAGGAAATCT GTGCCGCTGC ACAGGCTACA GACCCATCCT CCAGGGCTTC 
CGGACCTTTG CCAGGGATGG TGGATGCTGT GGAGGAGATG GGAATAATCC AAATTGCTGC 
ATGAACCAGA AGAAAGACCA CTCAGTCAGC CTCTCGCCAT CTTTATTCAA ACCAGAGGAG 
TTCACGCCCC TGGATCCAAC CCAGGAGCCC ATTTTTCCCC CAGAGTTGCT GAGGCTGAAA 
GACACTCCTC GGAAGCAGCT GCGATTTGAA GGGGAGCGTG TGACGTGGAT ACAGGCCTCA 
ACCCTCAAGG AGCTGCTGGA CCTCAAGGCT CAGCACCCTG ACGCCAAGCT GGTCGTGGGG 
AACACGGAGA TTGGCATTGA GATGAAGTTC AAGAATATGC TGTTTCCTAT GATTGTCTGC 
CCAGCCTGGA TCCCTGAGCT GAATTCGGTA GAACATGGAC CCGACGGTAT CTCCTTTGGA 
GCTGCTTGCC CCCTGAGCAT TGTGGAAAAA ACCCTGGTGG ATGCTGTTGC TAAGCTTCCT 
GCCCAAAAGA CAGAGGTGTT CAGAGGGGTC CTGGAGCAGC TGCGCTGGTT TGCTGGGAAG 
CAAGTCAAGT CTGTGGCGTC CGTTGGAGGG AACATCATCA CTGCCAGCCC CATCTCCGAC 
CTCAACCCCG TGTTCATGGC CAGTGGGGCC AAGCTGACAC TTGTGTCCAG AGGCACCAGG 
AGAACTGTCC AGATGGACCA CACCTTCTTC CCTGGCTACA GAAAGACCCT GCTGAGCCCG 
GAGGAGATAC TGCTCTCCAT AGAGATCCCC TACAGCAGGG AGGGGGAGTA TTTCTCAGCA 
TTCAAGCAGG CCTCCCGGAG AGAAGATGAC ATTGCCAAGG TAACCAGTGG CATGAGAGTT 
TTATTCAAGC CAGGAACCAC AGAGGTACAG GAGCTGGCCC TTTGCTATGG TGGAATGGCC 
AACAGAACCA TCTCAGCCCT CAAGACCACT CAGAGGCAGC TTTCCAAGCT CTGGAAGGAG 
GAGCTGCTGC AGGACGTGTG TGCAGGACTG GCAGAGGAGC TGCATCTGCC TCCCGATGCC 
CCTGGTGGCA TGGTGGACTT CCGGTGCACC CTCACCCTCA GCTTCTTCTT CAAGTTCTAC 
CTGACAGTCC TTCAGAAGCT GGGCCAAGAG AACCTGGAAG ACAAGTGTGG TAAACTGGAC 
CCCACTTTCG CCAGTGCAAC TTTACTGTTT CAGAAAGACC CCCCAGCCGA TGTCCAGCTC 
TTCCAAGAGG TGCCCAAGGG TCAGTCTGAG GAGGACATGG TGGGCCGGCC CCTGCCCCAC 
CTGGCAGCGG ACATGCAGGC CTCTGGTGAG GCCGTGTACT GTGACGACAT TCCTCGCTAC 
GAGAATGAGC TGTCTCTCCG GCTGGTCACC AGCACCCGGG CCCACGCCAA GATCAAGTCC 
ATAGATACAT CAGAAGCTAA GAAGGTTCCA GGGTTTGTTT GTTTCATTTC CGCTGATGAT 
GTTCCTGGGA GTAACATAAC TGGAATTTGT AATGATGAGA CAGTCTTTGC GAAGGATAAG 
GTTACTTGTG TTGGGCATAT CATTGGTGCT GTGGTTGCTG ACACCCCGGA ACACACACAG 
AGAGCTGCCC AAGGGGTGAA AATCACCTAT GAAGAACTAC CAGCCATTAT CACAATTGAG 
GATGCTATAA AGAACAACTC CTTTTATGGA CCTGAGCTGA AGATCGAGAA AGGGGACCTA 
AAGAAGGGGT TTTCCGAAGC AGATAATGTT GTGTCAGGGG AGATATACAT CGGTGGCCAA 
GAGCACTTCT ACCTGGAGAC TCACTGCACC ATTGCTGTTC CAAAAGGCGA GGCAGGGGAG 
ATGGAGCTCT TTGTGTCTAC ACAGAACACC ATGAAGACCC AGAGCTTTGT TGCAAAAATG 
TTGGGGGTTC CAGCAAACCG GATTGTGGTT CGAGTGAAGA GAATGGGAGG AGGCTTTGGA 
GGCAAGGAGA CCCGGAGCAC TGTGGTGTCC ACGGCAGTGG CCCTGGCTGC ATATAAGACC 
GGCCGCCCTG TGCGATGCAT GCTGGACCGT GATGAGGACA TGCTGATAAC TGGTGGCAGA 
CATCCCTTCC TGGCCAGATA CAAGGTTGGC TTCATGAAGA CTGGGACAGT TGTGGCTCTT 
GAGGTGGACC ACTTCAGCAA TGTGGGGAAC ACCCAGGATC TCTCTCAGAG TATTATGGAA 
CGAGCTTTAT TCCACATGGA CAACTGCTAT AAAATCCCCA ACATCCGGGG CACTGGGCGG 
CTGTGCAAAA CCAACCTTCC CTCCAACACG GCCTTCCGGG GCTTTGGGGG GCCCCAGGGG 
ATGCTCATTG CCGAGTGCTG GATGAGTGAA GTTGCAGTGA CCTGTGGGAT GCCTGCAGAG 
GAGGTGCGGA GAAAAAACCT GTACAAAGAA GGGGACCTGA CACACTTCAA CCAGAAGCTT 
GAGGGTTTCA CCTTGCCCAG ATGCTGGGAA GAATGCCTAG CAAGCTCTCA GTATCATGCT 
CGGAAGAGTG AGGTTGACAA GTTCAACAAG GAGAATTGTT GGAAAAAGAG AGGATTGTGC 
ATAATTCCCA CCAAGTTTGG AATAAGCTTT ACAGTTCCTT TTCTGAATCA GGCAGGAGCC 
CTACTTCATG TGTACACAGA TGGCTCTGTG CTGCTGACCC ACGGGGGGAC TGAGATGGGC 
CAAGGCCTTC ATACCAAAAT GGTCCAGGTG GCCAGTAGAG CTCTGAAAAT CCCCACCTCT 
AAGATTTATA TCAGCGAGAC AAGCACTAAC ACTGTGCCCA ACACCTCTCC CACGGCTGCC 
TCTGTCAGCG CTGACCTCAA TGGACAGGCC GTCTATGCGG CTTGTCAGAC CATCTTGAAA 
AGGCTGGAAC CCTACAAGAA GAAGAATCCC AGTGGCTCCT GGGAAGACTG GGTCACAGCT 
GCCTACATGG ACACAGTGAG CTTGTCTGCC ACTGGGTTTT ATAGAACACC CAATCTGGGC 
TACAGCTTTG AGACTAACTC AGGGAACCCC TTCCACTACT TCAGCTATGG GGTGGCTTGC 
TCTGAAGTAG AAATCGACTG CCTAACAGGA GATCATAAGA ACCTCCGCAC AGATATTGTC 
ATGGATGTTG GCTCCAGTCT AAACCCTGCC ATTGATATTG GACAGGTGGA AGGGGCATTT 
GTCCAGGGCC TTGGCCTCTT CACCCTAGAG GAGCTACACT ATTCCCCCGA GGGGAGCCTG 
CACACCCGTG GCCCTAGCAC CTACAAGATC CCGGCATTTG GCAGCATCCC CATTGAGTTC 
AGGGTGTCCC TGCTCCGCGA CTGCCCCAAC AAGAAGGCCA TCTATGCATC GAAGGCTGTT 
GGAGAGCCGC CCCTCTTCCT GGCTGCTTCT ATCTTCTTTG CCATCAAAGA TGCCATCCGT 
GCAGCTCGAG CTCAGCACAC AGGTAATAAC GTGAAGGAAC TCTTCCGGCT AGACAGCCCT 
GCCACCCCGG AGAAGATCCG CAATGCCTGC GTGGACAAGT TCACCACCCT GTGTGTCACT 
GGTGTCCCAG AAAACTGCAA ACCCTGGTCT GTGAGGGTCT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.
PloS one12(9)e0184260(2017)
Huff RD,Hsu AC,Nichol KS,Jones B,Knight DA,Wark PAB,Hansbro PM,Hirota JA

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XDH cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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