NR1H2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	NR1H2
Entrez Gene ID	7376
Full Name	nuclear receptor subfamily 1 group H member 2
Synonyms	LXR-b,LXRB,NER,NER-I,RIP15,UNR
General protein information	Preferred Names nuclear receptor subfamily 1 group H member 2 Names oxysterols receptor LXR-beta LX receptor beta liver X nuclear receptor beta nuclear orphan receptor LXR-beta nuclear receptor NER steroid hormone-nuclear receptor NER ubiquitously-expressed nuclear receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 19 Map Location: 19q13.33
Summary	The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 [PubMed 19436111]).[supplied by OMIM, Jan 2010].
Disorder MIM:	600380

mRNA and Protein(s)

mRNA	Protein	Name
NM_007121.6	NP_009052.4	oxysterols receptor LXR-beta isoform 1
NM_007121.7	NP_009052.4	oxysterols receptor LXR-beta isoform 1
NM_007121.5	NP_009052.3	oxysterols receptor LXR-beta isoform 1
NM_001256647.1	NP_001243576.1	oxysterols receptor LXR-beta isoform 2
NM_001256647.2	NP_001243576.2	oxysterols receptor LXR-beta isoform 2

Pathways from BioSystems

Homologies

Homo sapiens (human)	NR1H2	NP_009052.3
Xenopus tropicalis (tropical clawed frog)	nr1h2	NP_001072853.1
Rattus norvegicus (Norway rat)	Nr1h2	NP_113814.1
Pan troglodytes (chimpanzee)	NR1H2	XP_512838.4
Canis lupus familiaris (dog)	NR1H2	XP_851316.1
Mus musculus (house mouse)	Nr1h2	NP_001272447.1
Drosophila melanogaster (fruit fly)	EcR	NP_724456.1
	NR1H2	XP_001115995.2
Bos taurus (cattle)	NR1H2	NP_001014883.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP012211	XP_320323.4

Gene Ontology
Bibliography

Related articles in PubMed

Expression of liver X receptors in normal and refractory carcinoma tissues of the human lung and pancreas.
Kashiwagi K, Yanagida M, Matsui D, Tanaka M, Sugimoto K, Chen H, Ichikawa-Tomikawa N, Marubashi S, Suzuki H, Chiba H
Histology and histopathology11949(2017 Nov)

Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.
Bobin-Dubigeon C, Chauvin A, Brillaud-Meflah V, Boiffard F, Joalland MP, Bard JM
Anticancer research37(10)5495-5498(2017 10)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Expression of some LXR-dependent genes of cholesterol trafficking is related to breast tumor characteristics, but not time to recurrence.
Title: Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.

These results suggested that 25-HC promoted ADC cell migration and invasion in an LXR-dependent manner in the monoculture system but that in the coculture system, the 25-HC-induced IL-1beta secretion enhanced the effect of 25-HC in an LXR-independent manner.
Title: 25-Hydroxycholesterol promotes migration and invasion of lung adenocarcinoma cells.

GW3965 significantly increases the expression of liver X nuclear receptor beta (LXRbeta) mRNA, while the liver X nuclear receptor alpha (LXRalpha( mRNA expression did not change a lot, and sensitizes gefitinib by inhibiting NF-kappa B (NF-kappaB) activation.
Title: Liver X receptors agonist GW3965 re-sensitizes gefitinib-resistant human non-small cell lung cancer cell to gefitinib treatment by inhibiting NF-?B in vitro.

Interactions among SNPs in nucleotide excision repair (NER) genes.
Title: Interactions among polymorphisms of NER genes prompt the risk of transplantation rejection.

ULK1 has a role in RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells
Title: Loss of ULK1 increases RPS6KB1-NCOR1 repression of NR1H/LXR-mediated Scd1 transcription and augments lipotoxicity in hepatic cells.

The following NR1H2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NR1H2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20228	NM_007121.5 Latest version!	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu20332	NM_001256647.1 Latest version!	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu107767	NM_001256647.2 Latest version!	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
OHu107822	NM_007121.7 Latest version!	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OHu107822	NM_007121.6	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

NR1H2 ( NM_007121.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_009052.3 Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu20228
Clone ID Related Accession (Same CDS sequence)	NM_007121.5
Accession Version	NM_007121.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1386bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	oxysterols receptor LXR-beta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA053472.1, BC047750.2 and AI252503.1. On Feb 15, 2012 this sequence version replaced NM_007121.4. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.210809.1, SRR1660805.224356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAAC AGCAGCAGGA GTCACAGTCA 
CAGTCGCAGT CACCTGTGGG GCCGCAGGGC AGCAGCAGCT CAGCCTCTGG GCCTGGGGCT 
TCCCCTGGTG GATCTGAGGC AGGCAGCCAG GGCTCCGGGG AAGGCGAGGG TGTCCAGCTA 
ACAGCGGCTC AAGAACTAAT GATCCAGCAG TTGGTGGCGG CCCAACTGCA GTGCAACAAA 
CGCTCCTTCT CCGACCAGCC CAAAGTCACG CCCTGGCCCC TGGGCGCAGA CCCCCAGTCC 
CGAGATGCCC GCCAGCAACG CTTTGCCCAC TTCACGGAGC TGGCCATCAT CTCAGTCCAG 
GAGATCGTGG ACTTCGCTAA GCAAGTGCCT GGTTTCCTGC AGCTGGGCCG GGAGGACCAG 
ATCGCCCTCC TGAAGGCATC CACTATCGAG ATCATGCTGC TAGAGACAGC CAGGCGCTAC 
AACCACGAGA CAGAGTGTAT CACCTTCTTG AAGGACTTCA CCTACAGCAA GGACGACTTC 
CACCGTGCAG GCCTGCAGGT GGAGTTCATC AACCCCATCT TCGAGTTCTC GCGGGCCATG 
CGGCGGCTGG GCCTGGACGA CGCTGAGTAC GCCCTGCTCA TCGCCATCAA CATCTTCTCG 
GCCGACCGGC CCAACGTGCA GGAGCCGGGC CGCGTGGAGG CGTTGCAGCA GCCCTACGTG 
GAGGCGCTGC TGTCCTACAC GCGCATCAAG AGGCCGCAGG ACCAGCTGCG CTTCCCGCGC 
ATGCTCATGA AGCTGGTGAG CCTGCGCACG CTGAGCTCTG TGCACTCGGA GCAGGTCTTC 
GCCTTGCGGC TCCAGGACAA GAAGCTGCCG CCTCTGCTGT CGGAGATCTG GGACGTCCAC 
GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009052.3
CDS	282..1667
Translation	MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_007121.5
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007121.5

ORF Insert Sequence:

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAAC AGCAGCAGGA GTCACAGTCA 
CAGTCGCAGT CACCTGTGGG GCCGCAGGGC AGCAGCAGCT CAGCCTCTGG GCCTGGGGCT 
TCCCCTGGTG GATCTGAGGC AGGCAGCCAG GGCTCCGGGG AAGGCGAGGG TGTCCAGCTA 
ACAGCGGCTC AAGAACTAAT GATCCAGCAG TTGGTGGCGG CCCAACTGCA GTGCAACAAA 
CGCTCCTTCT CCGACCAGCC CAAAGTCACG CCCTGGCCCC TGGGCGCAGA CCCCCAGTCC 
CGAGATGCCC GCCAGCAACG CTTTGCCCAC TTCACGGAGC TGGCCATCAT CTCAGTCCAG 
GAGATCGTGG ACTTCGCTAA GCAAGTGCCT GGTTTCCTGC AGCTGGGCCG GGAGGACCAG 
ATCGCCCTCC TGAAGGCATC CACTATCGAG ATCATGCTGC TAGAGACAGC CAGGCGCTAC 
AACCACGAGA CAGAGTGTAT CACCTTCTTG AAGGACTTCA CCTACAGCAA GGACGACTTC 
CACCGTGCAG GCCTGCAGGT GGAGTTCATC AACCCCATCT TCGAGTTCTC GCGGGCCATG 
CGGCGGCTGG GCCTGGACGA CGCTGAGTAC GCCCTGCTCA TCGCCATCAA CATCTTCTCG 
GCCGACCGGC CCAACGTGCA GGAGCCGGGC CGCGTGGAGG CGTTGCAGCA GCCCTACGTG 
GAGGCGCTGC TGTCCTACAC GCGCATCAAG AGGCCGCAGG ACCAGCTGCG CTTCCCGCGC 
ATGCTCATGA AGCTGGTGAG CCTGCGCACG CTGAGCTCTG TGCACTCGGA GCAGGTCTTC 
GCCTTGCGGC TCCAGGACAA GAAGCTGCCG CCTCTGCTGT CGGAGATCTG GGACGTCCAC 
GAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NR1H2 ( NM_001256647.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243576.1 Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20332
Clone ID Related Accession (Same CDS sequence)	NM_001256647.1
Accession Version	NM_001256647.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1095bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-10
Organism	Homo sapiens(human)
Product	oxysterols receptor LXR-beta isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA053472.1, AK297978.1, BC047750.2 and AI252503.1. Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.41166.1, AK297978.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END##

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GGCGTCCTTT CTGAAGAACA GATCCGGAAG AAGAAGATTC GGAAACAACA GCAGCAGGAG 
TCACAGTCAC AGTCGCAGTC ACCTGTGGGG CCGCAGGGCA GCAGCAGCTC AGCCTCTGGG 
CCTGGGGCTT CCCCTGGTGG ATCTGAGGCA GGCAGCCAGG GCTCCGGGGA AGGCGAGGGT 
GTCCAGCTAA CAGCGGCTCA AGAACTAATG ATCCAGCAGT TGGTGGCGGC CCAACTGCAG 
TGCAACAAAC GCTCCTTCTC CGACCAGCCC AAAGTCACGC CCTGGCCCCT GGGCGCAGAC 
CCCCAGTCCC GAGATGCCCG CCAGCAACGC TTTGCCCACT TCACGGAGCT GGCCATCATC 
TCAGTCCAGG AGATCGTGGA CTTCGCTAAG CAAGTGCCTG GTTTCCTGCA GCTGGGCCGG 
GAGGACCAGA TCGCCCTCCT GAAGGCATCC ACTATCGAGA TCATGCTGCT AGAGACAGCC 
AGGCGCTACA ACCACGAGAC AGAGTGTATC ACCTTCTTGA AGGACTTCAC CTACAGCAAG 
GACGACTTCC ACCGTGCAGG CCTGCAGGTG GAGTTCATCA ACCCCATCTT CGAGTTCTCG 
CGGGCCATGC GGCGGCTGGG CCTGGACGAC GCTGAGTACG CCCTGCTCAT CGCCATCAAC 
ATCTTCTCGG CCGACCGGCC CAACGTGCAG GAGCCGGGCC GCGTGGAGGC GTTGCAGCAG 
CCCTACGTGG AGGCGCTGCT GTCCTACACG CGCATCAAGA GGCCGCAGGA CCAGCTGCGC 
TTCCCGCGCA TGCTCATGAA GCTGGTGAGC CTGCGCACGC TGAGCTCTGT GCACTCGGAG 
CAGGTCTTCG CCTTGCGGCT CCAGGACAAG AAGCTGCCGC CTCTGCTGTC GGAGATCTGG 
GACGTCCACG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243576.1
CDS	282..1376
Translation	MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWGVLSEEQIRKKKIRKQQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_001256647.1
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256647.1

ORF Insert Sequence:

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GGCGTCCTTT CTGAAGAACA GATCCGGAAG AAGAAGATTC GGAAACAACA GCAGCAGGAG 
TCACAGTCAC AGTCGCAGTC ACCTGTGGGG CCGCAGGGCA GCAGCAGCTC AGCCTCTGGG 
CCTGGGGCTT CCCCTGGTGG ATCTGAGGCA GGCAGCCAGG GCTCCGGGGA AGGCGAGGGT 
GTCCAGCTAA CAGCGGCTCA AGAACTAATG ATCCAGCAGT TGGTGGCGGC CCAACTGCAG 
TGCAACAAAC GCTCCTTCTC CGACCAGCCC AAAGTCACGC CCTGGCCCCT GGGCGCAGAC 
CCCCAGTCCC GAGATGCCCG CCAGCAACGC TTTGCCCACT TCACGGAGCT GGCCATCATC 
TCAGTCCAGG AGATCGTGGA CTTCGCTAAG CAAGTGCCTG GTTTCCTGCA GCTGGGCCGG 
GAGGACCAGA TCGCCCTCCT GAAGGCATCC ACTATCGAGA TCATGCTGCT AGAGACAGCC 
AGGCGCTACA ACCACGAGAC AGAGTGTATC ACCTTCTTGA AGGACTTCAC CTACAGCAAG 
GACGACTTCC ACCGTGCAGG CCTGCAGGTG GAGTTCATCA ACCCCATCTT CGAGTTCTCG 
CGGGCCATGC GGCGGCTGGG CCTGGACGAC GCTGAGTACG CCCTGCTCAT CGCCATCAAC 
ATCTTCTCGG CCGACCGGCC CAACGTGCAG GAGCCGGGCC GCGTGGAGGC GTTGCAGCAG 
CCCTACGTGG AGGCGCTGCT GTCCTACACG CGCATCAAGA GGCCGCAGGA CCAGCTGCGC 
TTCCCGCGCA TGCTCATGAA GCTGGTGAGC CTGCGCACGC TGAGCTCTGT GCACTCGGAG 
CAGGTCTTCG CCTTGCGGCT CCAGGACAAG AAGCTGCCGC CTCTGCTGTC GGAGATCTGG 
GACGTCCACG AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NR1H2 ( NM_001256647.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001243576.2 Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu107767
Clone ID Related Accession (Same CDS sequence)	NM_001256647.2
Accession Version	NM_001256647.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1092bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-25
Organism	Homo sapiens(human)
Product	oxysterols receptor LXR-beta isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA053472.1, AK297978.1, BC047750.2 and AI252503.1. On Sep 15, 2018 this sequence version replaced NM_001256647.1. Transcript Variant: This variant (2) lacks an exon in the 5' coding region, but maintains the reading frame, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. CCDS Note: The coding region was updated to make it identical to the current human reference genome sequence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.41166.1, SRR3476690.346851.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1970526 [ECO:0000348] ##Evidence-Data-END##

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GGCGTCCTTT CTGAAGAACA GATCCGGAAG AAGAAGATTC GGAAACAGCA GCAGGAGTCA 
CAGTCACAGT CGCAGTCACC TGTGGGGCCG CAGGGCAGCA GCAGCTCAGC CTCTGGGCCT 
GGGGCTTCCC CTGGTGGATC TGAGGCAGGC AGCCAGGGCT CCGGGGAAGG CGAGGGTGTC 
CAGCTAACAG CGGCTCAAGA ACTAATGATC CAGCAGTTGG TGGCGGCCCA ACTGCAGTGC 
AACAAACGCT CCTTCTCCGA CCAGCCCAAA GTCACGCCCT GGCCCCTGGG CGCAGACCCC 
CAGTCCCGAG ATGCCCGCCA GCAACGCTTT GCCCACTTCA CGGAGCTGGC CATCATCTCA 
GTCCAGGAGA TCGTGGACTT CGCTAAGCAA GTGCCTGGTT TCCTGCAGCT GGGCCGGGAG 
GACCAGATCG CCCTCCTGAA GGCATCCACT ATCGAGATCA TGCTGCTAGA GACAGCCAGG 
CGCTACAACC ACGAGACAGA GTGTATCACC TTCTTGAAGG ACTTCACCTA CAGCAAGGAC 
GACTTCCACC GTGCAGGCCT GCAGGTGGAG TTCATCAACC CCATCTTCGA GTTCTCGCGG 
GCCATGCGGC GGCTGGGCCT GGACGACGCT GAGTACGCCC TGCTCATCGC CATCAACATC 
TTCTCGGCCG ACCGGCCCAA CGTGCAGGAG CCGGGCCGCG TGGAGGCGTT GCAGCAGCCC 
TACGTGGAGG CGCTGCTGTC CTACACGCGC ATCAAGAGGC CGCAGGACCA GCTGCGCTTC 
CCGCGCATGC TCATGAAGCT GGTGAGCCTG CGCACGCTGA GCTCTGTGCA CTCGGAGCAG 
GTCTTCGCCT TGCGGCTCCA GGACAAGAAG CTGCCGCCTC TGCTGTCGGA GATCTGGGAC 
GTCCACGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001243576.2
CDS	248..1339
Translation	MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWGVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_001256647.2
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001256647.2

ORF Insert Sequence:

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GGCGTCCTTT CTGAAGAACA GATCCGGAAG AAGAAGATTC GGAAACAGCA GCAGGAGTCA 
CAGTCACAGT CGCAGTCACC TGTGGGGCCG CAGGGCAGCA GCAGCTCAGC CTCTGGGCCT 
GGGGCTTCCC CTGGTGGATC TGAGGCAGGC AGCCAGGGCT CCGGGGAAGG CGAGGGTGTC 
CAGCTAACAG CGGCTCAAGA ACTAATGATC CAGCAGTTGG TGGCGGCCCA ACTGCAGTGC 
AACAAACGCT CCTTCTCCGA CCAGCCCAAA GTCACGCCCT GGCCCCTGGG CGCAGACCCC 
CAGTCCCGAG ATGCCCGCCA GCAACGCTTT GCCCACTTCA CGGAGCTGGC CATCATCTCA 
GTCCAGGAGA TCGTGGACTT CGCTAAGCAA GTGCCTGGTT TCCTGCAGCT GGGCCGGGAG 
GACCAGATCG CCCTCCTGAA GGCATCCACT ATCGAGATCA TGCTGCTAGA GACAGCCAGG 
CGCTACAACC ACGAGACAGA GTGTATCACC TTCTTGAAGG ACTTCACCTA CAGCAAGGAC 
GACTTCCACC GTGCAGGCCT GCAGGTGGAG TTCATCAACC CCATCTTCGA GTTCTCGCGG 
GCCATGCGGC GGCTGGGCCT GGACGACGCT GAGTACGCCC TGCTCATCGC CATCAACATC 
TTCTCGGCCG ACCGGCCCAA CGTGCAGGAG CCGGGCCGCG TGGAGGCGTT GCAGCAGCCC 
TACGTGGAGG CGCTGCTGTC CTACACGCGC ATCAAGAGGC CGCAGGACCA GCTGCGCTTC 
CCGCGCATGC TCATGAAGCT GGTGAGCCTG CGCACGCTGA GCTCTGTGCA CTCGGAGCAG 
GTCTTCGCCT TGCGGCTCCA GGACAAGAAG CTGCCGCCTC TGCTGTCGGA GATCTGGGAC 
GTCCACGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NR1H2 ( NM_007121.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_009052.4 Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

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CloneID	OHu107822
Clone ID Related Accession (Same CDS sequence)	NM_007121.6 , NM_007121.7
Accession Version	NM_007121.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-27
Organism	Homo sapiens(human)
Product	oxysterols receptor LXR-beta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA053472.1, BC047750.2 and AI252503.1. On Sep 16, 2018 this sequence version replaced NM_007121.5. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: The coding region was updated to make it identical to the current human reference genome sequence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.249390.1, SRR1660805.224356.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAGC AGCAGGAGTC ACAGTCACAG 
TCGCAGTCAC CTGTGGGGCC GCAGGGCAGC AGCAGCTCAG CCTCTGGGCC TGGGGCTTCC 
CCTGGTGGAT CTGAGGCAGG CAGCCAGGGC TCCGGGGAAG GCGAGGGTGT CCAGCTAACA 
GCGGCTCAAG AACTAATGAT CCAGCAGTTG GTGGCGGCCC AACTGCAGTG CAACAAACGC 
TCCTTCTCCG ACCAGCCCAA AGTCACGCCC TGGCCCCTGG GCGCAGACCC CCAGTCCCGA 
GATGCCCGCC AGCAACGCTT TGCCCACTTC ACGGAGCTGG CCATCATCTC AGTCCAGGAG 
ATCGTGGACT TCGCTAAGCA AGTGCCTGGT TTCCTGCAGC TGGGCCGGGA GGACCAGATC 
GCCCTCCTGA AGGCATCCAC TATCGAGATC ATGCTGCTAG AGACAGCCAG GCGCTACAAC 
CACGAGACAG AGTGTATCAC CTTCTTGAAG GACTTCACCT ACAGCAAGGA CGACTTCCAC 
CGTGCAGGCC TGCAGGTGGA GTTCATCAAC CCCATCTTCG AGTTCTCGCG GGCCATGCGG 
CGGCTGGGCC TGGACGACGC TGAGTACGCC CTGCTCATCG CCATCAACAT CTTCTCGGCC 
GACCGGCCCA ACGTGCAGGA GCCGGGCCGC GTGGAGGCGT TGCAGCAGCC CTACGTGGAG 
GCGCTGCTGT CCTACACGCG CATCAAGAGG CCGCAGGACC AGCTGCGCTT CCCGCGCATG 
CTCATGAAGC TGGTGAGCCT GCGCACGCTG AGCTCTGTGC ACTCGGAGCA GGTCTTCGCC 
TTGCGGCTCC AGGACAAGAA GCTGCCGCCT CTGCTGTCGG AGATCTGGGA CGTCCACGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009052.4
CDS	248..1630
Translation	MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_007121.6
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007121.6

ORF Insert Sequence:

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAGC AGCAGGAGTC ACAGTCACAG 
TCGCAGTCAC CTGTGGGGCC GCAGGGCAGC AGCAGCTCAG CCTCTGGGCC TGGGGCTTCC 
CCTGGTGGAT CTGAGGCAGG CAGCCAGGGC TCCGGGGAAG GCGAGGGTGT CCAGCTAACA 
GCGGCTCAAG AACTAATGAT CCAGCAGTTG GTGGCGGCCC AACTGCAGTG CAACAAACGC 
TCCTTCTCCG ACCAGCCCAA AGTCACGCCC TGGCCCCTGG GCGCAGACCC CCAGTCCCGA 
GATGCCCGCC AGCAACGCTT TGCCCACTTC ACGGAGCTGG CCATCATCTC AGTCCAGGAG 
ATCGTGGACT TCGCTAAGCA AGTGCCTGGT TTCCTGCAGC TGGGCCGGGA GGACCAGATC 
GCCCTCCTGA AGGCATCCAC TATCGAGATC ATGCTGCTAG AGACAGCCAG GCGCTACAAC 
CACGAGACAG AGTGTATCAC CTTCTTGAAG GACTTCACCT ACAGCAAGGA CGACTTCCAC 
CGTGCAGGCC TGCAGGTGGA GTTCATCAAC CCCATCTTCG AGTTCTCGCG GGCCATGCGG 
CGGCTGGGCC TGGACGACGC TGAGTACGCC CTGCTCATCG CCATCAACAT CTTCTCGGCC 
GACCGGCCCA ACGTGCAGGA GCCGGGCCGC GTGGAGGCGT TGCAGCAGCC CTACGTGGAG 
GCGCTGCTGT CCTACACGCG CATCAAGAGG CCGCAGGACC AGCTGCGCTT CCCGCGCATG 
CTCATGAAGC TGGTGAGCCT GCGCACGCTG AGCTCTGTGC ACTCGGAGCA GGTCTTCGCC 
TTGCGGCTCC AGGACAAGAA GCTGCCGCCT CTGCTGTCGG AGATCTGGGA CGTCCACGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

NR1H2 ( NM_007121.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_009052.4 Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

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CloneID	OHu107822
Clone ID Related Accession (Same CDS sequence)	NM_007121.6 , NM_007121.7
Accession Version	NM_007121.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-31
Organism	Homo sapiens(human)
Product	oxysterols receptor LXR-beta isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA053472.1, BC047750.2, AI252503.1 and AC008655.7. On May 17, 2019 this sequence version replaced NM_007121.6. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). CCDS Note: The coding region was updated to make it identical to the current human reference genome sequence. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.249390.1, SRR1803611.102460.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000253727.10/ ENSP00000253727.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAGC AGCAGGAGTC ACAGTCACAG 
TCGCAGTCAC CTGTGGGGCC GCAGGGCAGC AGCAGCTCAG CCTCTGGGCC TGGGGCTTCC 
CCTGGTGGAT CTGAGGCAGG CAGCCAGGGC TCCGGGGAAG GCGAGGGTGT CCAGCTAACA 
GCGGCTCAAG AACTAATGAT CCAGCAGTTG GTGGCGGCCC AACTGCAGTG CAACAAACGC 
TCCTTCTCCG ACCAGCCCAA AGTCACGCCC TGGCCCCTGG GCGCAGACCC CCAGTCCCGA 
GATGCCCGCC AGCAACGCTT TGCCCACTTC ACGGAGCTGG CCATCATCTC AGTCCAGGAG 
ATCGTGGACT TCGCTAAGCA AGTGCCTGGT TTCCTGCAGC TGGGCCGGGA GGACCAGATC 
GCCCTCCTGA AGGCATCCAC TATCGAGATC ATGCTGCTAG AGACAGCCAG GCGCTACAAC 
CACGAGACAG AGTGTATCAC CTTCTTGAAG GACTTCACCT ACAGCAAGGA CGACTTCCAC 
CGTGCAGGCC TGCAGGTGGA GTTCATCAAC CCCATCTTCG AGTTCTCGCG GGCCATGCGG 
CGGCTGGGCC TGGACGACGC TGAGTACGCC CTGCTCATCG CCATCAACAT CTTCTCGGCC 
GACCGGCCCA ACGTGCAGGA GCCGGGCCGC GTGGAGGCGT TGCAGCAGCC CTACGTGGAG 
GCGCTGCTGT CCTACACGCG CATCAAGAGG CCGCAGGACC AGCTGCGCTT CCCGCGCATG 
CTCATGAAGC TGGTGAGCCT GCGCACGCTG AGCTCTGTGC ACTCGGAGCA GGTCTTCGCC 
TTGCGGCTCC AGGACAAGAA GCTGCCGCCT CTGCTGTCGG AGATCTGGGA CGTCCACGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_009052.4
CDS	248..1630
Translation	MSSPTTSSLDTPLPGNGPPQPGAPSSSPTVKEEGPEPWPGGPDPDVPGTDEASSACSTDWVIPDPEEEPERKRKKGPAPKMLGHELCRVCGDKASGFHYNVLSCEGCKGFFRRSVVRGGARRYACRGGGTCQMDAFMRRKCQQCRLRKCKEAGMREQCVLSEEQIRKKKIRKQQQESQSQSQSPVGPQGSSSSASGPGASPGGSEAGSQGSGEGEGVQLTAAQELMIQQLVAAQLQCNKRSFSDQPKVTPWPLGADPQSRDARQQRFAHFTELAIISVQEIVDFAKQVPGFLQLGREDQIALLKASTIEIMLLETARRYNHETECITFLKDFTYSKDDFHRAGLQVEFINPIFEFSRAMRRLGLDDAEYALLIAINIFSADRPNVQEPGRVEALQQPYVEALLSYTRIKRPQDQLRFPRMLMKLVSLRTLSSVHSEQVFALRLQDKKLPPLLSEIWDVHE

Target ORF information:

RefSeq Version	NM_007121.7
Organism	Homo sapiens(human)
Definition	Homo sapiens nuclear receptor subfamily 1 group H member 2 (NR1H2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_007121.7

ORF Insert Sequence:

ATGTCCTCTC CTACCACGAG TTCCCTGGAT ACCCCCCTGC CTGGAAATGG CCCCCCTCAG 
CCTGGCGCCC CTTCTTCTTC ACCCACTGTA AAGGAGGAGG GTCCGGAGCC GTGGCCCGGG 
GGTCCGGACC CTGATGTCCC AGGCACTGAT GAGGCCAGCT CAGCCTGCAG CACAGACTGG 
GTCATCCCAG ATCCCGAAGA GGAACCAGAG CGCAAGCGAA AGAAGGGCCC AGCCCCGAAG 
ATGCTGGGCC ACGAGCTTTG CCGTGTCTGT GGGGACAAGG CCTCCGGCTT CCACTACAAC 
GTGCTCAGCT GCGAAGGCTG CAAGGGCTTC TTCCGGCGCA GTGTGGTCCG TGGTGGGGCC 
AGGCGCTATG CCTGCCGGGG TGGCGGAACC TGCCAGATGG ACGCTTTCAT GCGGCGCAAG 
TGCCAGCAGT GCCGGCTGCG CAAGTGCAAG GAGGCAGGGA TGAGGGAGCA GTGCGTCCTT 
TCTGAAGAAC AGATCCGGAA GAAGAAGATT CGGAAACAGC AGCAGGAGTC ACAGTCACAG 
TCGCAGTCAC CTGTGGGGCC GCAGGGCAGC AGCAGCTCAG CCTCTGGGCC TGGGGCTTCC 
CCTGGTGGAT CTGAGGCAGG CAGCCAGGGC TCCGGGGAAG GCGAGGGTGT CCAGCTAACA 
GCGGCTCAAG AACTAATGAT CCAGCAGTTG GTGGCGGCCC AACTGCAGTG CAACAAACGC 
TCCTTCTCCG ACCAGCCCAA AGTCACGCCC TGGCCCCTGG GCGCAGACCC CCAGTCCCGA 
GATGCCCGCC AGCAACGCTT TGCCCACTTC ACGGAGCTGG CCATCATCTC AGTCCAGGAG 
ATCGTGGACT TCGCTAAGCA AGTGCCTGGT TTCCTGCAGC TGGGCCGGGA GGACCAGATC 
GCCCTCCTGA AGGCATCCAC TATCGAGATC ATGCTGCTAG AGACAGCCAG GCGCTACAAC 
CACGAGACAG AGTGTATCAC CTTCTTGAAG GACTTCACCT ACAGCAAGGA CGACTTCCAC 
CGTGCAGGCC TGCAGGTGGA GTTCATCAAC CCCATCTTCG AGTTCTCGCG GGCCATGCGG 
CGGCTGGGCC TGGACGACGC TGAGTACGCC CTGCTCATCG CCATCAACAT CTTCTCGGCC 
GACCGGCCCA ACGTGCAGGA GCCGGGCCGC GTGGAGGCGT TGCAGCAGCC CTACGTGGAG 
GCGCTGCTGT CCTACACGCG CATCAAGAGG CCGCAGGACC AGCTGCGCTT CCCGCGCATG 
CTCATGAAGC TGGTGAGCCT GCGCACGCTG AGCTCTGTGC ACTCGGAGCA GGTCTTCGCC 
TTGCGGCTCC AGGACAAGAA GCTGCCGCCT CTGCTGTCGG AGATCTGGGA CGTCCACGAG 
TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of liver X receptors in normal and refractory carcinoma tissues of the human lung and pancreas.
Histology and histopathology11949(2017 Nov)
Kashiwagi K,Yanagida M,Matsui D,Tanaka M,Sugimoto K,Chen H,Ichikawa-Tomikawa N,Marubashi S,Suzuki H,Chiba H

Liver X Receptor (LXR)-regulated Genes of Cholesterol Trafficking and Breast Cancer Severity.
Anticancer research37(10)5495-5498(2017 10)
Bobin-Dubigeon C,Chauvin A,Brillaud-Meflah V,Boiffard F,Joalland MP,Bard JM

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NR1H2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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