| Gene Symbol | TDO2 |
| Entrez Gene ID | 6999 |
| Full Name | tryptophan 2,3-dioxygenase |
| Synonyms | HYPTRP,TDO,TO,TPH2,TRPO |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Summary | This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]. |
| Disorder MIM: | |
| Disorder Html: | [?Hypertryptophanemia], 600627 (3) |









































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