TBCC cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TBCC
Entrez Gene ID	6903
Full Name	tubulin folding cofactor C
Synonyms	CFC
General protein information	Preferred Names tubulin folding cofactor C Names tubulin-specific chaperone C
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 6 Map Location: 6p21.1
Summary	Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state. [provided by RefSeq, Jul 2008].
Disorder MIM:	602971

mRNA and Protein(s)

mRNA	Protein	Name
NM_003192.2	NP_003183.1	tubulin-specific chaperone C
NM_003192.3	NP_003183.2	tubulin-specific chaperone C

Pathways from BioSystems

Homologies

Homo sapiens (human)	TBCC	NP_003183.1
	TBCC	XP_001088723.2
Bos taurus (cattle)	TBCC	NP_001069177.1
Arabidopsis thaliana (thale cress)	POR	NP_195702.1
Xenopus tropicalis (tropical clawed frog)	tbcc	XP_002934722.2
Pan troglodytes (chimpanzee)	TBCC	XP_518477.1
Mus musculus (house mouse)	Tbcc	NP_848472.2
Canis lupus familiaris (dog)	TBCC	XP_005627418.1
Rattus norvegicus (Norway rat)	Tbcc	NP_001101670.1
Gallus gallus (chicken)	TBCC	XP_003640986.2
Danio rerio (zebrafish)	tbccl	NP_001243177.1
Drosophila melanogaster (fruit fly)	CG31961	NP_722960.1

Gene Ontology
Bibliography

Related articles in PubMed

The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction.
Garcia-Mayoral MF, Casta?o R, Fanarraga ML, Zabala JC, Rico M, Bruix M
PloS one6(10)e25912(2011)

Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
Hage-Sleiman R, Herveau S, Matera EL, Laurier JF, Dumontet C
BMC cancer10135(2010 Apr)

The DNA sequence and analysis of human chromosome 6.
Mungall AJ, Palmer SA, Sims SK, Edwards CA, Ashurst JL, Wilming L, Jones MC, Horton R, Hunt SE, Scott CE, Gilbert JG, Clamp ME, Bethel G, Milne S, Ainscough R, Almeida JP, Ambrose KD, Andrews TD, Ashwell RI, Babbage AK, Bagguley CL, Bailey J, Banerjee R, Barker DJ, Barlow KF, Bates K, Beare DM, Beasley H, Beasley O, Bird CP, Blakey S, Bray-Allen S, Brook J, Brown AJ, Brown JY, Burford DC, Burrill W, Burton J, Carder C, Carter NP, Chapman JC, Clark SY, Clark G, Clee CM, Clegg S, Cobley V, Collier RE, Collins JE, Colman LK, Corby NR, Coville GJ, Culley KM, Dhami P, Davies J, Dunn M, Earthrowl ME, Ellington AE, Evans KA, Faulkner L, Francis MD, Frankish A, Frankland J, French L, Garner P, Garnett J, Ghori MJ, Gilby LM, Gillson CJ, Glithero RJ, Grafham DV, Grant M, Gribble S, Griffiths C, Griffiths M, Hall R, Halls KS, Hammond S, Harley JL, Hart EA, Heath PD, Heathcott R, Holmes SJ, Howden PJ, Howe KL, Howell GR, Huckle E, Humphray SJ, Humphries MD, Hunt AR, Johnson CM, Joy AA, Kay M, Keenan SJ, Kimberley AM, King A, Laird GK, Langford C, Lawlor S, Leongamornlert DA, Leversha M, Lloyd CR, Lloyd DM, Loveland JE, Lovell J, Martin S, Mashreghi-Mohammadi M, Maslen GL, Matthews L, McCann OT, McLaren SJ, McLay K, McMurray A, Moore MJ, Mullikin JC, Niblett D, Nickerson T, Novik KL, Oliver K, Overton-Larty EK, Parker A, Patel R, Pearce AV, Peck AI, Phillimore B, Phillips S, Plumb RW, Porter KM, Ramsey Y, Ranby SA, Rice CM, Ross MT, Searle SM, Sehra HK, Sheridan E, Skuce CD, Smith S, Smith M, Spraggon L, Squares SL, Steward CA, Sycamore N, Tamlyn-Hall G, Tester J, Theaker AJ, Thomas DW, Thorpe A, Tracey A, Tromans A, Tubby B, Wall M, Wallis JM, West AP, White SS, Whitehead SL, Whittaker H, Wild A, Willey DJ, Wilmer TE, Wood JM, Wray PW, Wyatt JC, Young L, Younger RM, Bentley DR, Coulson A, Durbin R, Hubbard T, Sulston JE, Dunham I, Rogers J, Beck S
Nature425(6960)805-11(2003 Oct)

Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3.
Grayson C, Bartolini F, Chapple JP, Willison KR, Bhamidipati A, Lewis SA, Luthert PJ, Hardcastle AJ, Cowan NJ, Cheetham ME
Human molecular genetics11(24)3065-74(2002 Nov)

Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.
Bartolini F, Bhamidipati A, Thomas S, Schwahn U, Lewis SA, Cowan NJ
The Journal of biological chemistry277(17)14629-34(2002 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

a testable model for TBCC N-terminal domain/tubulin recognition in which the highly charged N-terminus as well as residues from the three helices and the loops interact with the acidic hypervariable regions of tubulin monomers
Title: The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction.

Microtubule dynamicity was reduced in breast cancer cells overexpressing TBCC. Cell cycle distribution was altered in cells containing larger amounts of TBCC. TBCC had little effect on cell proliferation.
Title: Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.

functional overlap with retinitis pigmenosa 2 protein
Title: Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.

The following TBCC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TBCC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu30271	NM_003192.2 Latest version!	Homo sapiens tubulin folding cofactor C (TBCC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu108597	NM_003192.3 Latest version!	Homo sapiens tubulin folding cofactor C (TBCC), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TBCC ( NM_003192.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_003183.1 Homo sapiens tubulin folding cofactor C (TBCC), mRNA.

Price & Availability↑

CloneID	OHu30271
Clone ID Related Accession (Same CDS sequence)	NM_003192.2
Accession Version	NM_003192.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Homo sapiens(human)
Product	tubulin-specific chaperone C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BE795945.1 and BC020170.1. On Dec 1, 2006 this sequence version replaced NM_003192.1.

ATGGAGTCCG TCAGTTGCTC CGCTGCTGCT GTCAGGACCG GAGACATGGA GTCCCAGCGG 
GACCTGAGCC TGGTGCCTGA GCGGCTTCAG AGACGCGAAC AAGAACGGCA GCTGGAAGTT 
GAAAGGCGGA AACAAAAGCG GCAGAACCAG GAGGTAGAGA AGGAGAACAG CCACTTTTTC 
GTCGCCACCT TTGCTCGGGA GCGAGCGGCC GTGGAAGAGC TTCTGGAGCG CGCGGAGTCG 
GTCGAGCGGC TGGAGGAGGC GGCCTCTCGG CTCCAGGGGC TGCAGAAACT AATCAACGAC 
TCAGTTTTTT TCCTAGCCGC TTACGACCTG CGGCAGGGAC AAGAGGCGCT GGCGCGGCTG 
CAGGCGGCCT TGGCCGAGCG GCGCCGGGGG CTGCAGCCCA AGAAGCGTTT CGCTTTCAAG 
ACCCGGGGAA AGGATGCTGC TTCGTCTACC AAAGTAGACG CGGCTCCTGG CATCCCCCCG 
GCAGTTGAAA GCATACAGGA CTCCCCGCTG CCCAAGAAGG CGGAAGGAGA CCTCGGCCCC 
AGCTGGGTCT GCGGTTTCTC CAACCTGGAG TCCCAAGTCT TGGAGAAGAG AGCCAGCGAG 
TTGCACCAGC GCGACGTTCT TTTGACCGAA CTGAGCAACT GCACGGTCAG ACTGTATGGA 
AATCCCAACA CCCTGCGGCT AACCAAGGCC CACAGCTGCA AGCTGCTCTG CGGTCCGGTG 
TCTACCTCTG TTTTCCTGGA GGACTGCAGT GACTGCGTGC TGGCAGTGGC CTGCCAACAG 
CTCCGCATAC ACAGTACGAA AGACACCCGC ATCTTCCTGC AGGTGACCAG CAGGGCCATC 
GTGGAGGACT GCAGTGGGAT CCAGTTCGCC CCTTACACCT GGAGCTACCC GGAGATCGAC 
AAGGACTTCG AGAGCTCTGG TTTAGATAGG AGCAAAAATA ACTGGAACGA TGTTGACGAT 
TTTAACTGGC TGGCCCGGGA TATGGCCTCC CCAAACTGGA GTATTCTTCC TGAAGAGGAG 
CGAAATATCC AGTGGGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003183.1
CDS	74..1114
Translation	MESVSCSAAAVRTGDMESQRDLSLVPERLQRREQERQLEVERRKQKRQNQEVEKENSHFFVATFARERAAVEELLERAESVERLEEAASRLQGLQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVDAAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSNCTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFLQVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNWSILPEEERNIQWD

Target ORF information:

RefSeq Version	NM_003192.2
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin folding cofactor C (TBCC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003192.2

ORF Insert Sequence:

ATGGAGTCCG TCAGTTGCTC CGCTGCTGCT GTCAGGACCG GAGACATGGA GTCCCAGCGG 
GACCTGAGCC TGGTGCCTGA GCGGCTTCAG AGACGCGAAC AAGAACGGCA GCTGGAAGTT 
GAAAGGCGGA AACAAAAGCG GCAGAACCAG GAGGTAGAGA AGGAGAACAG CCACTTTTTC 
GTCGCCACCT TTGCTCGGGA GCGAGCGGCC GTGGAAGAGC TTCTGGAGCG CGCGGAGTCG 
GTCGAGCGGC TGGAGGAGGC GGCCTCTCGG CTCCAGGGGC TGCAGAAACT AATCAACGAC 
TCAGTTTTTT TCCTAGCCGC TTACGACCTG CGGCAGGGAC AAGAGGCGCT GGCGCGGCTG 
CAGGCGGCCT TGGCCGAGCG GCGCCGGGGG CTGCAGCCCA AGAAGCGTTT CGCTTTCAAG 
ACCCGGGGAA AGGATGCTGC TTCGTCTACC AAAGTAGACG CGGCTCCTGG CATCCCCCCG 
GCAGTTGAAA GCATACAGGA CTCCCCGCTG CCCAAGAAGG CGGAAGGAGA CCTCGGCCCC 
AGCTGGGTCT GCGGTTTCTC CAACCTGGAG TCCCAAGTCT TGGAGAAGAG AGCCAGCGAG 
TTGCACCAGC GCGACGTTCT TTTGACCGAA CTGAGCAACT GCACGGTCAG ACTGTATGGA 
AATCCCAACA CCCTGCGGCT AACCAAGGCC CACAGCTGCA AGCTGCTCTG CGGTCCGGTG 
TCTACCTCTG TTTTCCTGGA GGACTGCAGT GACTGCGTGC TGGCAGTGGC CTGCCAACAG 
CTCCGCATAC ACAGTACGAA AGACACCCGC ATCTTCCTGC AGGTGACCAG CAGGGCCATC 
GTGGAGGACT GCAGTGGGAT CCAGTTCGCC CCTTACACCT GGAGCTACCC GGAGATCGAC 
AAGGACTTCG AGAGCTCTGG TTTAGATAGG AGCAAAAATA ACTGGAACGA TGTTGACGAT 
TTTAACTGGC TGGCCCGGGA TATGGCCTCC CCAAACTGGA GTATTCTTCC TGAAGAGGAG 
CGAAATATCC AGTGGGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TBCC ( NM_003192.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_003183.2 Homo sapiens tubulin folding cofactor C (TBCC), mRNA.

Price & Availability↑

CloneID	OHu108597
Clone ID Related Accession (Same CDS sequence)	NM_003192.3
Accession Version	NM_003192.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1041bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-20
Organism	Homo sapiens(human)
Product	tubulin-specific chaperone C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL353716.18. On May 17, 2019 this sequence version replaced NM_003192.2. ##Evidence-Data-START## Transcript is intronless :: SRR3476690.452306.1, SRR3476690.353594.1 [ECO:0000345] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372876.2/ ENSP00000361967.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END##

ATGGAGTCCG TCAGTTGCTC CGCTGCTGCT GTCAGGACCG GAGACATGGA GTCCCAGCGG 
GACCTGAGCC TGGTGCCTGA GCGGCTTCAG AGACGCGAAC AAGAACGGCA GCTGGAAGTT 
GAAAGGCGGA AACAAAAGCG GCAGAACCAG GAGGTAGAGA AGGAGAACAG CCACTTTTTC 
GTCGCCACCT TTGTTCGGGA GCGAGCGGCC GTGGAAGAGC TTCTGGAGCG CGCGGAGTCG 
GTCGAGCGGC TGGAGGAGGC GGCCTCTCGG CTCCAGGGGC TGCAGAAACT AATCAACGAC 
TCAGTTTTTT TCCTAGCCGC TTACGACCTG CGGCAGGGAC AAGAGGCGCT GGCGCGGCTG 
CAGGCGGCCT TGGCCGAGCG GCGCCGGGGG CTGCAGCCCA AGAAGCGTTT CGCTTTCAAG 
ACCCGGGGAA AGGATGCTGC TTCGTCTACC AAAGTAGACG CGGCTCCTGG CATCCCCCCG 
GCAGTTGAAA GCATACAGGA CTCCCCGCTG CCCAAGAAGG CGGAAGGAGA CCTCGGCCCC 
AGCTGGGTCT GCGGTTTCTC CAACCTGGAG TCCCAAGTCT TGGAGAAGAG AGCCAGCGAG 
TTGCACCAGC GCGACGTTCT TTTGACCGAA CTGAGCAACT GCACGGTCAG ACTGTATGGA 
AATCCCAACA CCCTGCGGCT AACCAAGGCC CACAGCTGCA AGCTGCTCTG CGGTCCGGTG 
TCTACCTCTG TTTTCCTGGA GGACTGCAGT GACTGCGTGC TGGCAGTGGC CTGCCAACAG 
CTCCGCATAC ACAGTACGAA AGACACCCGC ATCTTCCTGC AGGTGACCAG CAGGGCCATC 
GTGGAGGACT GCAGTGGGAT CCAGTTCGCC CCTTACACCT GGAGCTACCC GGAGATCGAC 
AAGGACTTCG AGAGCTCTGG TTTAGATAGG AGCAAAAATA ACTGGAACGA TGTTGACGAT 
TTTAACTGGC TGGCCCGGGA TATGGCCTCC CCAAACTGGA GTATTCTTCC TGAAGAGGAG 
CGAAATATCC AGTGGGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003183.2
CDS	31..1071
Translation	MESVSCSAAAVRTGDMESQRDLSLVPERLQRREQERQLEVERRKQKRQNQEVEKENSHFFVATFVRERAAVEELLERAESVERLEEAASRLQGLQKLINDSVFFLAAYDLRQGQEALARLQAALAERRRGLQPKKRFAFKTRGKDAASSTKVDAAPGIPPAVESIQDSPLPKKAEGDLGPSWVCGFSNLESQVLEKRASELHQRDVLLTELSNCTVRLYGNPNTLRLTKAHSCKLLCGPVSTSVFLEDCSDCVLAVACQQLRIHSTKDTRIFLQVTSRAIVEDCSGIQFAPYTWSYPEIDKDFESSGLDRSKNNWNDVDDFNWLARDMASPNWSILPEEERNIQWD

Target ORF information:

RefSeq Version	NM_003192.3
Organism	Homo sapiens(human)
Definition	Homo sapiens tubulin folding cofactor C (TBCC), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003192.3

ORF Insert Sequence:

ATGGAGTCCG TCAGTTGCTC CGCTGCTGCT GTCAGGACCG GAGACATGGA GTCCCAGCGG 
GACCTGAGCC TGGTGCCTGA GCGGCTTCAG AGACGCGAAC AAGAACGGCA GCTGGAAGTT 
GAAAGGCGGA AACAAAAGCG GCAGAACCAG GAGGTAGAGA AGGAGAACAG CCACTTTTTC 
GTCGCCACCT TTGTTCGGGA GCGAGCGGCC GTGGAAGAGC TTCTGGAGCG CGCGGAGTCG 
GTCGAGCGGC TGGAGGAGGC GGCCTCTCGG CTCCAGGGGC TGCAGAAACT AATCAACGAC 
TCAGTTTTTT TCCTAGCCGC TTACGACCTG CGGCAGGGAC AAGAGGCGCT GGCGCGGCTG 
CAGGCGGCCT TGGCCGAGCG GCGCCGGGGG CTGCAGCCCA AGAAGCGTTT CGCTTTCAAG 
ACCCGGGGAA AGGATGCTGC TTCGTCTACC AAAGTAGACG CGGCTCCTGG CATCCCCCCG 
GCAGTTGAAA GCATACAGGA CTCCCCGCTG CCCAAGAAGG CGGAAGGAGA CCTCGGCCCC 
AGCTGGGTCT GCGGTTTCTC CAACCTGGAG TCCCAAGTCT TGGAGAAGAG AGCCAGCGAG 
TTGCACCAGC GCGACGTTCT TTTGACCGAA CTGAGCAACT GCACGGTCAG ACTGTATGGA 
AATCCCAACA CCCTGCGGCT AACCAAGGCC CACAGCTGCA AGCTGCTCTG CGGTCCGGTG 
TCTACCTCTG TTTTCCTGGA GGACTGCAGT GACTGCGTGC TGGCAGTGGC CTGCCAACAG 
CTCCGCATAC ACAGTACGAA AGACACCCGC ATCTTCCTGC AGGTGACCAG CAGGGCCATC 
GTGGAGGACT GCAGTGGGAT CCAGTTCGCC CCTTACACCT GGAGCTACCC GGAGATCGAC 
AAGGACTTCG AGAGCTCTGG TTTAGATAGG AGCAAAAATA ACTGGAACGA TGTTGACGAT 
TTTAACTGGC TGGCCCGGGA TATGGCCTCC CCAAACTGGA GTATTCTTCC TGAAGAGGAG 
CGAAATATCC AGTGGGACTA A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

The solution structure of the N-terminal domain of human tubulin binding cofactor C reveals a platform for tubulin interaction.
PloS one6(10)e25912(2011)
Garcia-Mayoral MF,Casta?o R,Fanarraga ML,Zabala JC,Rico M,Bruix M

Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
BMC cancer10135(2010 Apr)
Hage-Sleiman R,Herveau S,Matera EL,Laurier JF,Dumontet C

The DNA sequence and analysis of human chromosome 6.
Nature425(6960)805-11(2003 Oct)
Mungall AJ,Palmer SA,Sims SK,Edwards CA,Ashurst JL,Wilming L,Jones MC,Horton R,Hunt SE,Scott CE,Gilbert JG,Clamp ME,Bethel G,Milne S,Ainscough R,Almeida JP,Ambrose KD,Andrews TD,Ashwell RI,Babbage AK,Bagguley CL,Bailey J,Banerjee R,Barker DJ,Barlow KF,Bates K,Beare DM,Beasley H,Beasley O,Bird CP,Blakey S,Bray-Allen S,Brook J,Brown AJ,Brown JY,Burford DC,Burrill W,Burton J,Carder C,Carter NP,Chapman JC,Clark SY,Clark G,Clee CM,Clegg S,Cobley V,Collier RE,Collins JE,Colman LK,Corby NR,Coville GJ,Culley KM,Dhami P,Davies J,Dunn M,Earthrowl ME,Ellington AE,Evans KA,Faulkner L,Francis MD,Frankish A,Frankland J,French L,Garner P,Garnett J,Ghori MJ,Gilby LM,Gillson CJ,Glithero RJ,Grafham DV,Grant M,Gribble S,Griffiths C,Griffiths M,Hall R,Halls KS,Hammond S,Harley JL,Hart EA,Heath PD,Heathcott R,Holmes SJ,Howden PJ,Howe KL,Howell GR,Huckle E,Humphray SJ,Humphries MD,Hunt AR,Johnson CM,Joy AA,Kay M,Keenan SJ,Kimberley AM,King A,Laird GK,Langford C,Lawlor S,Leongamornlert DA,Leversha M,Lloyd CR,Lloyd DM,Loveland JE,Lovell J,Martin S,Mashreghi-Mohammadi M,Maslen GL,Matthews L,McCann OT,McLaren SJ,McLay K,McMurray A,Moore MJ,Mullikin JC,Niblett D,Nickerson T,Novik KL,Oliver K,Overton-Larty EK,Parker A,Patel R,Pearce AV,Peck AI,Phillimore B,Phillips S,Plumb RW,Porter KM,Ramsey Y,Ranby SA,Rice CM,Ross MT,Searle SM,Sehra HK,Sheridan E,Skuce CD,Smith S,Smith M,Spraggon L,Squares SL,Steward CA,Sycamore N,Tamlyn-Hall G,Tester J,Theaker AJ,Thomas DW,Thorpe A,Tracey A,Tromans A,Tubby B,Wall M,Wallis JM,West AP,White SS,Whitehead SL,Whittaker H,Wild A,Willey DJ,Wilmer TE,Wood JM,Wray PW,Wyatt JC,Young L,Younger RM,Bentley DR,Coulson A,Durbin R,Hubbard T,Sulston JE,Dunham I,Rogers J,Beck S

Localization in the human retina of the X-linked retinitis pigmentosa protein RP2, its homologue cofactor C and the RP2 interacting protein Arl3.
Human molecular genetics11(24)3065-74(2002 Nov)
Grayson C,Bartolini F,Chapple JP,Willison KR,Bhamidipati A,Lewis SA,Luthert PJ,Hardcastle AJ,Cowan NJ,Cheetham ME

Functional overlap between retinitis pigmentosa 2 protein and the tubulin-specific chaperone cofactor C.
The Journal of biological chemistry277(17)14629-34(2002 Apr)
Bartolini F,Bhamidipati A,Thomas S,Schwahn U,Lewis SA,Cowan NJ

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TBCC cDNA ORF clone, Homo sapiens(human)

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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