SRP72 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SRP72
Entrez Gene ID	6731
Full Name	signal recognition particle 72
Synonyms	BMFF,BMFS1,HEL103
General protein information	Preferred Names signal recognition particle 72 Names signal recognition particle subunit SRP72 epididymis luminal protein 103 signal recognition particle 72 kDa protein signal recognition particle 72kD signal recognition particle 72kDa
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4q12
Summary	This gene encodes the 72 kDa subunit of the signal recognition particle (SRP), a ribonucleoprotein complex that mediates the targeting of secretory proteins to the endoplasmic reticulum (ER). The SRP complex consists of a 7S RNA and 6 protein subunits: SRP9, SRP14, SRP19, SRP54, SRP68, and SRP72, that are bound to the 7S RNA as monomers or heterodimers. SRP has at least 3 distinct functions that can be associated with the protein subunits: signal recognition, translational arrest, and ER membrane targeting by interaction with the docking protein. Mutations in this gene are associated with familial bone marrow failure. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2012].
Disorder MIM:	602122
Disorder Html:	Bone marrow failure syndrome 1, 614675 (3)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005265765.4	XP_005265822.3	signal recognition particle subunit SRP72 isoform X1
NM_001267722.2	NP_001254651.1	signal recognition particle subunit SRP72 isoform 2
NM_001267722.1	NP_001254651.1	signal recognition particle subunit SRP72 isoform 2
NM_006947.4	NP_008878.3	signal recognition particle subunit SRP72 isoform 1
NM_006947.3	NP_008878.3	signal recognition particle subunit SRP72 isoform 1
XM_024454192.1	XP_024309960.1	signal recognition particle subunit SRP72 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Srp72	NP_001164072.1
Danio rerio (zebrafish)	srp72	XP_002664308.3
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP001939	XP_321122.4
Xenopus tropicalis (tropical clawed frog)	srp72	NP_001116259.1
Pan troglodytes (chimpanzee)	SRP72	XP_001139671.3
Gallus gallus (chicken)	SRP72	NP_001006449.1
Drosophila melanogaster (fruit fly)	Srp72	NP_650898.1
Caenorhabditis elegans (roundworm)	CELE_F08D12.1	NP_494366.2
Arabidopsis thaliana (thale cress)	AT1G67650	NP_176933.1
	SRP72	XP_001085253.1
Bos taurus (cattle)	SRP72	NP_001179150.1
Oryza sativa (rice)	Os01g0889000	NP_001045044.1
Homo sapiens (human)	SRP72	NP_008878.3
Canis lupus familiaris (dog)	SRP72	NP_001003264.1
Mus musculus (house mouse)	Srp72	NP_079967.1
Arabidopsis thaliana (thale cress)	AT1G67680	NP_176936.1

Gene Ontology
Bibliography

Related articles in PubMed

Depletion of signal recognition particle 72kDa increases radiosensitivity.
Prevo R, Tiwana GS, Maughan TS, Buffa FM, McKenna WG, Higgins GS
Cancer biology & therapy18(6)425-432(2017 Jun)

Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.
Gao Y, Zhang Q, Lang Y, Liu Y, Dong X, Chen Z, Tian W, Tang J, Wu W, Tong Y, Chen Z
Journal of molecular cell biology9(3)220-230(2017 Jun)

Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Becker MM, Lapouge K, Segnitz B, Wild K, Sinning I
Nucleic acids research45(1)470-481(2017 Jan)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The crystal structures of the SRP68 protein-binding domain (PBD) in complex with SRP72-PBD and of the SRP72-RBD bound to the SRP S domain (SRP RNA, SRP19 and SRP68) detailing all interactions of SRP72 within SRP have been presented.
Title: Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.

SRP68/72 heterodimers as major nuclear proteins whose binding of histone H4 tail is inhibited by H4R3 methylation.
Title: A novel histone H4 arginine 3 methylation-sensitive histone H4 binding activity and transcriptional regulatory function for signal recognition particle subunits SRP68 and SRP72.

A heterozygous mutation in SRP72 has a role in familial aplasia and myelodysplasia.
Title: Exome sequencing identifies autosomal-dominant SRP72 mutations associated with familial aplasia and myelodysplasia.

The study delineated the minimal region of SRP72 capable of forming a stable complex with an signal recognition particle RNA fragment.
Title: Identification of amino acid residues in protein SRP72 required for binding to a kinked 5e motif of the human signal recognition particle RNA.

Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells.
Title: Inhibitors of MAPK pathway ERK1/2 or p38 prevent the IL-1{beta}-induced up-regulation of SRP72 autoantigen in Jurkat cells.

The following SRP72 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SRP72 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu26527	NM_001267722.2 Latest version!	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu26521	NM_006947.4 Latest version!	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
OHu60734	XM_024454192.1 Latest version!	Homo sapiens signal recognition particle 72 (SRP72), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu95379	XM_005265765.4 Latest version!	Homo sapiens signal recognition particle 72kDa (SRP72), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu26527	NM_001267722.1	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
OHu26521	NM_006947.3	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$475.30 $679.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SRP72 ( NM_001267722.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254651.1 Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26527
Clone ID Related Accession (Same CDS sequence)	NM_001267722.2 , NM_001267722.1
Accession Version	NM_001267722.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	signal recognition particle subunit SRP72 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487204.2, AF069765.1, BX537991.1, BM985263.1, AK023480.1 and BM985419.1. On May 31, 2019 this sequence version replaced NM_001267722.1. Transcript Variant: This variant (2) lacks 2 consecutive in-frame coding exons in the 5' region compared to variant 1, which results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX537991.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGACCAAAA TGTCTTTGAC 
TCCAAGAAGA AAGTGAAATT AACCAATGCG GAAGGAGTAG AGTTTAAGCT TTCCAAGAAA 
CAACTACAAG CTATAGAATT TAACAAAGCT TTACTTGCTA TGTACACAAA CCAGGCTGAA 
CAATGCCGCA AAATATCTGC CAGTTTACAG TCCCAAAGTC CCGAGCATCT CTTACCTGTG 
TTAATCCAAG CTGCCCAGCT CTGCCGTGAA AAGCAGCACA CAAAAGCAAT AGAGCTGCTT 
CAGGAATTTT CAGATCAGCA TCCAGAAAAT GCAGCTGAAA TTAAGCTGAC CATGGCACAG 
TTGAAAATTT CTCAAGGTAA TATTTCTAAA GCATGTCTAA TATTGAGAAG CATAGAGGAG 
TTAAAGCATA AACCAGGCAT GGTATCTGCA TTAGTTACCA TGTATAGCCA TGAAGAAGAT 
ATTGATAGTG CCATTGAGGT CTTCACACAA GCTATCCAGT GGTATCAAAA CCATCAGCCA 
AAATCTCCTG CTCATTTGTC CTTGATAAGA GAAGCTGCAA ACTTCAAACT CAAATATGGG 
CGGAAGAAGG AGGCAATTAG TGACCTACAA CAGCTGTGGA AACAAAATCC AAAAGATATT 
CACACCCTGG CACAGCTTAT TTCTGCTTAC TCACTTGTAG ATCCAGAGAA AGCCAAAGCT 
CTTAGTAAAC ACTTGCCATC GTCAGATAGT ATGTCTCTAA AAGTAGATGT TGAGGCTCTT 
GAAAATTCTG CTGGTGCTAC ATACATTCGG AAGAAGGGTG GAAAAGTTAC TGGAGATAGT 
CAACCAAAGG AACAAGGACA GGGAGATTTG AAAAAGAAGA AAAAGAAAAA GAAGGGAAAA 
TTGCCTAAGA ATTATGACCC AAAAGTTACC CCAGATCCAG AAAGATGGCT GCCAATGCGA 
GAACGTTCTT ACTACCGGGG AAGAAAGAAG GGTAAAAAGA AGGATCAGAT TGGAAAAGGG 
ACCCAGGGAG CAACTGCAGG AGCTTCATCT GAACTGGATG CCAGTAAAAC TGTGAGCAGC 
CCACCCACCT CCCCAAGACC TGGCAGTGCT GCAACAGTAT CTGCCTCTAC AAGTAACATC 
ATACCCCCAA GACACCAGAA ACCTGCAGGG GCTCCAGCAA CAAAAAAGAA ACAGCAACAG 
AAAAAGAAGA AAGGTGGAAA AGGTGGCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254651.1
CDS	20..1852
Translation	MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW

Target ORF information:

RefSeq Version	NM_001267722.2
Organism	Homo sapiens(human)
Definition	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267722.2

ORF Insert Sequence:

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGACCAAAA TGTCTTTGAC 
TCCAAGAAGA AAGTGAAATT AACCAATGCG GAAGGAGTAG AGTTTAAGCT TTCCAAGAAA 
CAACTACAAG CTATAGAATT TAACAAAGCT TTACTTGCTA TGTACACAAA CCAGGCTGAA 
CAATGCCGCA AAATATCTGC CAGTTTACAG TCCCAAAGTC CCGAGCATCT CTTACCTGTG 
TTAATCCAAG CTGCCCAGCT CTGCCGTGAA AAGCAGCACA CAAAAGCAAT AGAGCTGCTT 
CAGGAATTTT CAGATCAGCA TCCAGAAAAT GCAGCTGAAA TTAAGCTGAC CATGGCACAG 
TTGAAAATTT CTCAAGGTAA TATTTCTAAA GCATGTCTAA TATTGAGAAG CATAGAGGAG 
TTAAAGCATA AACCAGGCAT GGTATCTGCA TTAGTTACCA TGTATAGCCA TGAAGAAGAT 
ATTGATAGTG CCATTGAGGT CTTCACACAA GCTATCCAGT GGTATCAAAA CCATCAGCCA 
AAATCTCCTG CTCATTTGTC CTTGATAAGA GAAGCTGCAA ACTTCAAACT CAAATATGGG 
CGGAAGAAGG AGGCAATTAG TGACCTACAA CAGCTGTGGA AACAAAATCC AAAAGATATT 
CACACCCTGG CACAGCTTAT TTCTGCTTAC TCACTTGTAG ATCCAGAGAA AGCCAAAGCT 
CTTAGTAAAC ACTTGCCATC GTCAGATAGT ATGTCTCTAA AAGTAGATGT TGAGGCTCTT 
GAAAATTCTG CTGGTGCTAC ATACATTCGG AAGAAGGGTG GAAAAGTTAC TGGAGATAGT 
CAACCAAAGG AACAAGGACA GGGAGATTTG AAAAAGAAGA AAAAGAAAAA GAAGGGAAAA 
TTGCCTAAGA ATTATGACCC AAAAGTTACC CCAGATCCAG AAAGATGGCT GCCAATGCGA 
GAACGTTCTT ACTACCGGGG AAGAAAGAAG GGTAAAAAGA AGGATCAGAT TGGAAAAGGG 
ACCCAGGGAG CAACTGCAGG AGCTTCATCT GAACTGGATG CCAGTAAAAC TGTGAGCAGC 
CCACCCACCT CCCCAAGACC TGGCAGTGCT GCAACAGTAT CTGCCTCTAC AAGTAACATC 
ATACCCCCAA GACACCAGAA ACCTGCAGGG GCTCCAGCAA CAAAAAAGAA ACAGCAACAG 
AAAAAGAAGA AAGGTGGAAA AGGTGGCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRP72 ( NM_001267722.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001254651.1 Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu26527
Clone ID Related Accession (Same CDS sequence)	NM_001267722.2 , NM_001267722.1
Accession Version	NM_001267722.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1833bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	signal recognition particle subunit SRP72 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487204.2, AF069765.1, BX537991.1, BM985263.1, AK023480.1 and BM985419.1. Transcript Variant: This variant (2) lacks 2 consecutive in-frame coding exons in the 5' region compared to variant 1, which results in a shorter isoform (2) missing an internal protein segment compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BX537991.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGACCAAAA TGTCTTTGAC 
TCCAAGAAGA AAGTGAAATT AACCAATGCG GAAGGAGTAG AGTTTAAGCT TTCCAAGAAA 
CAACTACAAG CTATAGAATT TAACAAAGCT TTACTTGCTA TGTACACAAA CCAGGCTGAA 
CAATGCCGCA AAATATCTGC CAGTTTACAG TCCCAAAGTC CCGAGCATCT CTTACCTGTG 
TTAATCCAAG CTGCCCAGCT CTGCCGTGAA AAGCAGCACA CAAAAGCAAT AGAGCTGCTT 
CAGGAATTTT CAGATCAGCA TCCAGAAAAT GCAGCTGAAA TTAAGCTGAC CATGGCACAG 
TTGAAAATTT CTCAAGGTAA TATTTCTAAA GCATGTCTAA TATTGAGAAG CATAGAGGAG 
TTAAAGCATA AACCAGGCAT GGTATCTGCA TTAGTTACCA TGTATAGCCA TGAAGAAGAT 
ATTGATAGTG CCATTGAGGT CTTCACACAA GCTATCCAGT GGTATCAAAA CCATCAGCCA 
AAATCTCCTG CTCATTTGTC CTTGATAAGA GAAGCTGCAA ACTTCAAACT CAAATATGGG 
CGGAAGAAGG AGGCAATTAG TGACCTACAA CAGCTGTGGA AACAAAATCC AAAAGATATT 
CACACCCTGG CACAGCTTAT TTCTGCTTAC TCACTTGTAG ATCCAGAGAA AGCCAAAGCT 
CTTAGTAAAC ACTTGCCATC GTCAGATAGT ATGTCTCTAA AAGTAGATGT TGAGGCTCTT 
GAAAATTCTG CTGGTGCTAC ATACATTCGG AAGAAGGGTG GAAAAGTTAC TGGAGATAGT 
CAACCAAAGG AACAAGGACA GGGAGATTTG AAAAAGAAGA AAAAGAAAAA GAAGGGAAAA 
TTGCCTAAGA ATTATGACCC AAAAGTTACC CCAGATCCAG AAAGATGGCT GCCAATGCGA 
GAACGTTCTT ACTACCGGGG AAGAAAGAAG GGTAAAAAGA AGGATCAGAT TGGAAAAGGG 
ACCCAGGGAG CAACTGCAGG AGCTTCATCT GAACTGGATG CCAGTAAAAC TGTGAGCAGC 
CCACCCACCT CCCCAAGACC TGGCAGTGCT GCAACAGTAT CTGCCTCTAC AAGTAACATC 
ATACCCCCAA GACACCAGAA ACCTGCAGGG GCTCCAGCAA CAAAAAAGAA ACAGCAACAG 
AAAAAGAAGA AAGGTGGAAA AGGTGGCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001254651.1
CDS	41..1873
Translation	MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW

Target ORF information:

RefSeq Version	NM_001267722.1
Organism	Homo sapiens(human)
Definition	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001267722.1

ORF Insert Sequence:

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGACCAAAA TGTCTTTGAC 
TCCAAGAAGA AAGTGAAATT AACCAATGCG GAAGGAGTAG AGTTTAAGCT TTCCAAGAAA 
CAACTACAAG CTATAGAATT TAACAAAGCT TTACTTGCTA TGTACACAAA CCAGGCTGAA 
CAATGCCGCA AAATATCTGC CAGTTTACAG TCCCAAAGTC CCGAGCATCT CTTACCTGTG 
TTAATCCAAG CTGCCCAGCT CTGCCGTGAA AAGCAGCACA CAAAAGCAAT AGAGCTGCTT 
CAGGAATTTT CAGATCAGCA TCCAGAAAAT GCAGCTGAAA TTAAGCTGAC CATGGCACAG 
TTGAAAATTT CTCAAGGTAA TATTTCTAAA GCATGTCTAA TATTGAGAAG CATAGAGGAG 
TTAAAGCATA AACCAGGCAT GGTATCTGCA TTAGTTACCA TGTATAGCCA TGAAGAAGAT 
ATTGATAGTG CCATTGAGGT CTTCACACAA GCTATCCAGT GGTATCAAAA CCATCAGCCA 
AAATCTCCTG CTCATTTGTC CTTGATAAGA GAAGCTGCAA ACTTCAAACT CAAATATGGG 
CGGAAGAAGG AGGCAATTAG TGACCTACAA CAGCTGTGGA AACAAAATCC AAAAGATATT 
CACACCCTGG CACAGCTTAT TTCTGCTTAC TCACTTGTAG ATCCAGAGAA AGCCAAAGCT 
CTTAGTAAAC ACTTGCCATC GTCAGATAGT ATGTCTCTAA AAGTAGATGT TGAGGCTCTT 
GAAAATTCTG CTGGTGCTAC ATACATTCGG AAGAAGGGTG GAAAAGTTAC TGGAGATAGT 
CAACCAAAGG AACAAGGACA GGGAGATTTG AAAAAGAAGA AAAAGAAAAA GAAGGGAAAA 
TTGCCTAAGA ATTATGACCC AAAAGTTACC CCAGATCCAG AAAGATGGCT GCCAATGCGA 
GAACGTTCTT ACTACCGGGG AAGAAAGAAG GGTAAAAAGA AGGATCAGAT TGGAAAAGGG 
ACCCAGGGAG CAACTGCAGG AGCTTCATCT GAACTGGATG CCAGTAAAAC TGTGAGCAGC 
CCACCCACCT CCCCAAGACC TGGCAGTGCT GCAACAGTAT CTGCCTCTAC AAGTAACATC 
ATACCCCCAA GACACCAGAA ACCTGCAGGG GCTCCAGCAA CAAAAAAGAA ACAGCAACAG 
AAAAAGAAGA AAGGTGGAAA AGGTGGCTGG TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRP72 ( NM_006947.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_008878.3 Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26521
Clone ID Related Accession (Same CDS sequence)	NM_006947.4 , NM_006947.3
Accession Version	NM_006947.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-13
Organism	Homo sapiens(human)
Product	signal recognition particle subunit SRP72 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487204.2, AF069765.1, BX537991.1, AC114766.5, CN270014.1 and BM985419.1. This sequence is a reference standard in the RefSeqGene project. On May 21, 2018 this sequence version replaced NM_006947.3. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF038851.1, SRR1660807.47424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000642900.1/ ENSP00000495128.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG ACAGGGAGAT TTGAAAAAGA AGAAAAAGAA AAAGAAGGGA 
AAATTGCCTA AGAATTATGA CCCAAAAGTT ACCCCAGATC CAGAAAGATG GCTGCCAATG 
CGAGAACGTT CTTACTACCG GGGAAGAAAG AAGGGTAAAA AGAAGGATCA GATTGGAAAA 
GGGACCCAGG GAGCAACTGC AGGAGCTTCA TCTGAACTGG ATGCCAGTAA AACTGTGAGC 
AGCCCACCCA CCTCCCCAAG ACCTGGCAGT GCTGCAACAG TATCTGCCTC TACAAGTAAC 
ATCATACCCC CAAGACACCA GAAACCTGCA GGGGCTCCAG CAACAAAAAA GAAACAGCAA 
CAGAAAAAGA AGAAAGGTGG AAAAGGTGGC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008878.3
CDS	20..2035
Translation	MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW

Target ORF information:

RefSeq Version	NM_006947.4
Organism	Homo sapiens(human)
Definition	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006947.4

ORF Insert Sequence:

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG ACAGGGAGAT TTGAAAAAGA AGAAAAAGAA AAAGAAGGGA 
AAATTGCCTA AGAATTATGA CCCAAAAGTT ACCCCAGATC CAGAAAGATG GCTGCCAATG 
CGAGAACGTT CTTACTACCG GGGAAGAAAG AAGGGTAAAA AGAAGGATCA GATTGGAAAA 
GGGACCCAGG GAGCAACTGC AGGAGCTTCA TCTGAACTGG ATGCCAGTAA AACTGTGAGC 
AGCCCACCCA CCTCCCCAAG ACCTGGCAGT GCTGCAACAG TATCTGCCTC TACAAGTAAC 
ATCATACCCC CAAGACACCA GAAACCTGCA GGGGCTCCAG CAACAAAAAA GAAACAGCAA 
CAGAAAAAGA AGAAAGGTGG AAAAGGTGGC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRP72 ( NM_006947.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_008878.3 Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu26521
Clone ID Related Accession (Same CDS sequence)	NM_006947.4 , NM_006947.3
Accession Version	NM_006947.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2016bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-06
Organism	Homo sapiens(human)
Product	signal recognition particle subunit SRP72 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB487204.2, AF069765.1, BX537991.1, AC114766.5, CN270014.1 and BM985419.1. This sequence is a reference standard in the RefSeqGene project. On Jun 24, 2006 this sequence version replaced NM_006947.2. Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF038851.1, SRR1660807.47424.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG ACAGGGAGAT TTGAAAAAGA AGAAAAAGAA AAAGAAGGGA 
AAATTGCCTA AGAATTATGA CCCAAAAGTT ACCCCAGATC CAGAAAGATG GCTGCCAATG 
CGAGAACGTT CTTACTACCG GGGAAGAAAG AAGGGTAAAA AGAAGGATCA GATTGGAAAA 
GGGACCCAGG GAGCAACTGC AGGAGCTTCA TCTGAACTGG ATGCCAGTAA AACTGTGAGC 
AGCCCACCCA CCTCCCCAAG ACCTGGCAGT GCTGCAACAG TATCTGCCTC TACAAGTAAC 
ATCATACCCC CAAGACACCA GAAACCTGCA GGGGCTCCAG CAACAAAAAA GAAACAGCAA 
CAGAAAAAGA AGAAAGGTGG AAAAGGTGGC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_008878.3
CDS	41..2056
Translation	MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGQGDLKKKKKKKKGKLPKNYDPKVTPDPERWLPMRERSYYRGRKKGKKKDQIGKGTQGATAGASSELDASKTVSSPPTSPRPGSAATVSASTSNIIPPRHQKPAGAPATKKKQQQKKKKGGKGGW

Target ORF information:

RefSeq Version	NM_006947.3
Organism	Homo sapiens(human)
Definition	Homo sapiens signal recognition particle 72 (SRP72), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_006947.3

ORF Insert Sequence:

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG ACAGGGAGAT TTGAAAAAGA AGAAAAAGAA AAAGAAGGGA 
AAATTGCCTA AGAATTATGA CCCAAAAGTT ACCCCAGATC CAGAAAGATG GCTGCCAATG 
CGAGAACGTT CTTACTACCG GGGAAGAAAG AAGGGTAAAA AGAAGGATCA GATTGGAAAA 
GGGACCCAGG GAGCAACTGC AGGAGCTTCA TCTGAACTGG ATGCCAGTAA AACTGTGAGC 
AGCCCACCCA CCTCCCCAAG ACCTGGCAGT GCTGCAACAG TATCTGCCTC TACAAGTAAC 
ATCATACCCC CAAGACACCA GAAACCTGCA GGGGCTCCAG CAACAAAAAA GAAACAGCAA 
CAGAAAAAGA AGAAAGGTGG AAAAGGTGGC TGGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRP72 ( XM_024454192.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024309960.1 Homo sapiens signal recognition particle 72 (SRP72), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu60734
Clone ID Related Accession (Same CDS sequence)	XM_024454192.1
Accession Version	XM_024454192.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1647bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	signal recognition particle subunit SRP72 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024309960.1
CDS	10..1656
Translation	MASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGA

Target ORF information:

RefSeq Version	XM_024454192.1
Organism	Homo sapiens(human)
Definition	Homo sapiens signal recognition particle 72 (SRP72), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024454192.1

ORF Insert Sequence:

ATGGCGAGCG GCGGCAGCGG GGGGGTGTCA GTACCTGCGC TGTGGAGTGA AGTGAACCGG 
TATGGCCAGA ACGGCGACTT CACGCGCGCT CTCAAGACCG TCAATAAGAT ACTACAGATC 
AACAAAGATG ACGTAACTGC CCTGCATTGT AAAGTGGTAT GCCTTATCCA GAATGGAAGT 
TTCAAGGAAG CTTTGAATGT CATCAATACT CACACCAAAG TGTTAGCCAA TAACTCTCTC 
TCCTTTGAAA AGGCATATTG CGAGTACAGG CTGAACAGAA TTGAGAATGC CTTGAAGACA 
ATAGAAAGTG CCAACCAGCA GACAGACAAA CTGAAGGAGC TTTATGGACA AGTGTTATAC 
CGTTTGGAAC GCTATGATGA ATGCTTAGCA GTGTATAGAG ATCTCGTCCG AAACTCCCAA 
GATGATTATG ATGAGGAGAG GAAAACAAAC CTTTCAGCAG TTGTTGCAGC TCAAAGCAAT 
TGGGAAAAAG TGGTTCCAGA GAACCTGGGC CTCCAAGAAG GCACACATGA GCTGTGCTAC 
AACACTGCAT GTGCACTGAT AGGCCAAGGC CAGCTGAACC AGGCCATGAA AATCCTACAA 
AAAGCTGAAG ATCTTTGCCG CCGTTCATTA TCAGAAGACA CTGATGGGAC TGAGGAAGAC 
CCACAGGCAG AACTGGCCAT CATTCATGGT CAGATGGCTT ATATTCTGCA GCTTCAGGGT 
CGAACAGAGG AGGCTTTGCA ACTTTACAAT CAAATAATAA AACTAAAACC AACAGATGTG 
GGATTACTAG CTGTAATTGC AAATAACATC ATTACCATTA ACAAGGACCA AAATGTCTTT 
GACTCCAAGA AGAAAGTGAA ATTAACCAAT GCGGAAGGAG TAGAGTTTAA GCTTTCCAAG 
AAACAACTAC AAGCTATAGA ATTTAACAAA GCTTTACTTG CTATGTACAC AAACCAGGCT 
GAACAATGCC GCAAAATATC TGCCAGTTTA CAGTCCCAAA GTCCCGAGCA TCTCTTACCT 
GTGTTAATCC AAGCTGCCCA GCTCTGCCGT GAAAAGCAGC ACACAAAAGC AATAGAGCTG 
CTTCAGGAAT TTTCAGATCA GCATCCAGAA AATGCAGCTG AAATTAAGCT GACCATGGCA 
CAGTTGAAAA TTTCTCAAGG TAATATTTCT AAAGCATGTC TAATATTGAG AAGCATAGAG 
GAGTTAAAGC ATAAACCAGG CATGGTATCT GCATTAGTTA CCATGTATAG CCATGAAGAA 
GATATTGATA GTGCCATTGA GGTCTTCACA CAAGCTATCC AGTGGTATCA AAACCATCAG 
CCAAAATCTC CTGCTCATTT GTCCTTGATA AGAGAAGCTG CAAACTTCAA ACTCAAATAT 
GGGCGGAAGA AGGAGGCAAT TAGTGACCTA CAACAGCTGT GGAAACAAAA TCCAAAAGAT 
ATTCACACCC TGGCACAGCT TATTTCTGCT TACTCACTTG TAGATCCAGA GAAAGCCAAA 
GCTCTTAGTA AACACTTGCC ATCGTCAGAT AGTATGTCTC TAAAAGTAGA TGTTGAGGCT 
CTTGAAAATT CTGCTGGTGC TACATACATT CGGAAGAAGG GTGGAAAAGT TACTGGAGAT 
AGTCAACCAA AGGAACAAGG GGCATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SRP72 ( XM_005265765.4 ) cDNA ORF clone, Homo sapiens(human) -> XP_005265822.3 Homo sapiens signal recognition particle 72kDa (SRP72), transcript variant X1, mRNA.

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CloneID	OHu95379
Clone ID Related Accession (Same CDS sequence)	XM_005265765.4
Accession Version	XM_005265765.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1992bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(Human)
Product	signal recognition particle subunit SRP72 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005265765.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGATCGTCC GGCCCCGCAC CGTGGGACCA GGACGCTGCC TCGACCATGG CGGTCTCCTG 
GAAACAGGCT GCTTTGAGCC GAAACTGGTG ACCGTTTCCC AACCCCGTCC AGGAGTCCGA 
CGCCTCTTTT CTCCAGGCCA ACTTCAAGTG AGGTGTATCA ACTCTATCCG CACAAATTTC 
TTGCCACGAG AGCAGAAGAT TATGATCTCT GATGCTGCCT TAGGGCTGAA GACACTCCCA 
ACTCGGCGAC GCTTAGCAAT CATCGACTTC CTCCTCCTCT TGGCTGCCTC GGAGATCCTG 
TTCCGGGGCA GAGGTCTCCC CGCCCCGCCC CTCGTCTCCT CCAAGATGGC GAGCGGCGGC 
AGCGGGGGGG TGTCAGTACC TGCGCTGTGG AGTGAAGTGA ACCGGTATGG CCAGAACGGC 
GACTTCACGC GCGCTCTCAA GACCGTCAAT AAGATACTAC AGATCAACAA AGATGACGTA 
ACTGCCCTGC ATTGTAAAGT GGTATGCCTT ATCCAGAATG GAAGTTTCAA GGAAGCTTTG 
AATGTCATCA ATACTCACAC CAAAGTGTTA GCCAATAACT CTCTCTCCTT TGAAAAGGCA 
TATTGCGAGT ACAGGCTGAA CAGAATTGAG AATGCCTTGA AGACAATAGA AAGTGCCAAC 
CAGCAGACAG ACAAACTGAA GGAGCTTTAT GGACAAGTGT TATACCGTTT GGAACGCTAT 
GATGAATGCT TAGCAGTGTA TAGAGATCTC GTCCGAAACT CCCAAGATGA TTATGATGAG 
GAGAGGAAAA CAAACCTTTC AGCAGTTGTT GCAGCTCAAA GCAATTGGGA AAAAGTGGTT 
CCAGAGAACC TGGGCCTCCA AGAAGGCACA CATGAGCTGT GCTACAACAC TGCATGTGCA 
CTGATAGGCC AAGGCCAGCT GAACCAGGCC ATGAAAATCC TACAAAAAGC TGAAGATCTT 
TGCCGCCGTT CATTATCAGA AGACACTGAT GGGACTGAGG AAGACCCACA GGCAGAACTG 
GCCATCATTC ATGGTCAGAT GGCTTATATT CTGCAGCTTC AGGGTCGAAC AGAGGAGGCT 
TTGCAACTTT ACAATCAAAT AATAAAACTA AAACCAACAG ATGTGGGATT ACTAGCTGTA 
ATTGCAAATA ACATCATTAC CATTAACAAG GACCAAAATG TCTTTGACTC CAAGAAGAAA 
GTGAAATTAA CCAATGCGGA AGGAGTAGAG TTTAAGCTTT CCAAGAAACA ACTACAAGCT 
ATAGAATTTA ACAAAGCTTT ACTTGCTATG TACACAAACC AGGCTGAACA ATGCCGCAAA 
ATATCTGCCA GTTTACAGTC CCAAAGTCCC GAGCATCTCT TACCTGTGTT AATCCAAGCT 
GCCCAGCTCT GCCGTGAAAA GCAGCACACA AAAGCAATAG AGCTGCTTCA GGAATTTTCA 
GATCAGCATC CAGAAAATGC AGCTGAAATT AAGCTGACCA TGGCACAGTT GAAAATTTCT 
CAAGGTAATA TTTCTAAAGC ATGTCTAATA TTGAGAAGCA TAGAGGAGTT AAAGCATAAA 
CCAGGCATGG TATCTGCATT AGTTACCATG TATAGCCATG AAGAAGATAT TGATAGTGCC 
ATTGAGGTCT TCACACAAGC TATCCAGTGG TATCAAAACC ATCAGCCAAA ATCTCCTGCT 
CATTTGTCCT TGATAAGAGA AGCTGCAAAC TTCAAACTCA AATATGGGCG GAAGAAGGAG 
GCAATTAGTG ACCTACAACA GCTGTGGAAA CAAAATCCAA AAGATATTCA CACCCTGGCA 
CAGCTTATTT CTGCTTACTC ACTTGTAGAT CCAGAGAAAG CCAAAGCTCT TAGTAAACAC 
TTGCCATCGT CAGATAGTAT GTCTCTAAAA GTAGATGTTG AGGCTCTTGA AAATTCTGCT 
GGTGCTACAT ACATTCGGAA GAAGGGTGGA AAAGTTACTG GAGATAGTCA ACCAAAGGAA 
CAAGGGGCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005265822.3
CDS	415..2406
Translation	MIVRPRTVGPGRCLDHGGLLETGCFEPKLVTVSQPRPGVRRLFSPGQLQVRCINSIRTNFLPREQKIMISDAALGLKTLPTRRRLAIIDFLLLLAASEILFRGRGLPAPPLVSSKMASGGSGGVSVPALWSEVNRYGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSLSFEKAYCEYRLNRIENALKTIESANQQTDKLKELYGQVLYRLERYDECLAVYRDLVRNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNTACALIGQGQLNQAMKILQKAEDLCRRSLSEDTDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLKPTDVGLLAVIANNIITINKDQNVFDSKKKVKLTNAEGVEFKLSKKQLQAIEFNKALLAMYTNQAEQCRKISASLQSQSPEHLLPVLIQAAQLCREKQHTKAIELLQEFSDQHPENAAEIKLTMAQLKISQGNISKACLILRSIEELKHKPGMVSALVTMYSHEEDIDSAIEVFTQAIQWYQNHQPKSPAHLSLIREAANFKLKYGRKKEAISDLQQLWKQNPKDIHTLAQLISAYSLVDPEKAKALSKHLPSSDSMSLKVDVEALENSAGATYIRKKGGKVTGDSQPKEQGA

Target ORF information:

RefSeq Version	XM_005265765.4
Organism	Homo sapiens(Human)
Definition	Homo sapiens signal recognition particle 72kDa (SRP72), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005265765.4

ORF Insert Sequence:

ATGATCGTCC GGCCCCGCAC CGTGGGACCA GGACGCTGCC TCGACCATGG CGGTCTCCTG 
GAAACAGGCT GCTTTGAGCC GAAACTGGTG ACCGTTTCCC AACCCCGTCC AGGAGTCCGA 
CGCCTCTTTT CTCCAGGCCA ACTTCAAGTG AGGTGTATCA ACTCTATCCG CACAAATTTC 
TTGCCACGAG AGCAGAAGAT TATGATCTCT GATGCTGCCT TAGGGCTGAA GACACTCCCA 
ACTCGGCGAC GCTTAGCAAT CATCGACTTC CTCCTCCTCT TGGCTGCCTC GGAGATCCTG 
TTCCGGGGCA GAGGTCTCCC CGCCCCGCCC CTCGTCTCCT CCAAGATGGC GAGCGGCGGC 
AGCGGGGGGG TGTCAGTACC TGCGCTGTGG AGTGAAGTGA ACCGGTATGG CCAGAACGGC 
GACTTCACGC GCGCTCTCAA GACCGTCAAT AAGATACTAC AGATCAACAA AGATGACGTA 
ACTGCCCTGC ATTGTAAAGT GGTATGCCTT ATCCAGAATG GAAGTTTCAA GGAAGCTTTG 
AATGTCATCA ATACTCACAC CAAAGTGTTA GCCAATAACT CTCTCTCCTT TGAAAAGGCA 
TATTGCGAGT ACAGGCTGAA CAGAATTGAG AATGCCTTGA AGACAATAGA AAGTGCCAAC 
CAGCAGACAG ACAAACTGAA GGAGCTTTAT GGACAAGTGT TATACCGTTT GGAACGCTAT 
GATGAATGCT TAGCAGTGTA TAGAGATCTC GTCCGAAACT CCCAAGATGA TTATGATGAG 
GAGAGGAAAA CAAACCTTTC AGCAGTTGTT GCAGCTCAAA GCAATTGGGA AAAAGTGGTT 
CCAGAGAACC TGGGCCTCCA AGAAGGCACA CATGAGCTGT GCTACAACAC TGCATGTGCA 
CTGATAGGCC AAGGCCAGCT GAACCAGGCC ATGAAAATCC TACAAAAAGC TGAAGATCTT 
TGCCGCCGTT CATTATCAGA AGACACTGAT GGGACTGAGG AAGACCCACA GGCAGAACTG 
GCCATCATTC ATGGTCAGAT GGCTTATATT CTGCAGCTTC AGGGTCGAAC AGAGGAGGCT 
TTGCAACTTT ACAATCAAAT AATAAAACTA AAACCAACAG ATGTGGGATT ACTAGCTGTA 
ATTGCAAATA ACATCATTAC CATTAACAAG GACCAAAATG TCTTTGACTC CAAGAAGAAA 
GTGAAATTAA CCAATGCGGA AGGAGTAGAG TTTAAGCTTT CCAAGAAACA ACTACAAGCT 
ATAGAATTTA ACAAAGCTTT ACTTGCTATG TACACAAACC AGGCTGAACA ATGCCGCAAA 
ATATCTGCCA GTTTACAGTC CCAAAGTCCC GAGCATCTCT TACCTGTGTT AATCCAAGCT 
GCCCAGCTCT GCCGTGAAAA GCAGCACACA AAAGCAATAG AGCTGCTTCA GGAATTTTCA 
GATCAGCATC CAGAAAATGC AGCTGAAATT AAGCTGACCA TGGCACAGTT GAAAATTTCT 
CAAGGTAATA TTTCTAAAGC ATGTCTAATA TTGAGAAGCA TAGAGGAGTT AAAGCATAAA 
CCAGGCATGG TATCTGCATT AGTTACCATG TATAGCCATG AAGAAGATAT TGATAGTGCC 
ATTGAGGTCT TCACACAAGC TATCCAGTGG TATCAAAACC ATCAGCCAAA ATCTCCTGCT 
CATTTGTCCT TGATAAGAGA AGCTGCAAAC TTCAAACTCA AATATGGGCG GAAGAAGGAG 
GCAATTAGTG ACCTACAACA GCTGTGGAAA CAAAATCCAA AAGATATTCA CACCCTGGCA 
CAGCTTATTT CTGCTTACTC ACTTGTAGAT CCAGAGAAAG CCAAAGCTCT TAGTAAACAC 
TTGCCATCGT CAGATAGTAT GTCTCTAAAA GTAGATGTTG AGGCTCTTGA AAATTCTGCT 
GGTGCTACAT ACATTCGGAA GAAGGGTGGA AAAGTTACTG GAGATAGTCA ACCAAAGGAA 
CAAGGGGCAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Depletion of signal recognition particle 72kDa increases radiosensitivity.
Cancer biology & therapy18(6)425-432(2017 Jun)
Prevo R,Tiwana GS,Maughan TS,Buffa FM,McKenna WG,Higgins GS

Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation.
Journal of molecular cell biology9(3)220-230(2017 Jun)
Gao Y,Zhang Q,Lang Y,Liu Y,Dong X,Chen Z,Tian W,Tang J,Wu W,Tong Y,Chen Z

Structures of human SRP72 complexes provide insights into SRP RNA remodeling and ribosome interaction.
Nucleic acids research45(1)470-481(2017 Jan)
Becker MM,Lapouge K,Segnitz B,Wild K,Sinning I

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

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SRP72 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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