SNRPB2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	SNRPB2
Entrez Gene ID	6629
Full Name	small nuclear ribonucleoprotein polypeptide B2
Synonyms	Msl1,U2B''
General protein information	Preferred Names small nuclear ribonucleoprotein polypeptide B2 Names U2 small nuclear ribonucleoprotein B'' U2 snRNP B'' small nuclear ribonucleoprotein polypeptide B
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p12.1
Summary	The protein encoded by this gene associates with stem loop IV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presence of snRNP-A'. The encoded protein may play a role in pre-mRNA splicing. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	603520

mRNA and Protein(s)

mRNA	Protein	Name
NM_003092.4	NP_003083.1	U2 small nuclear ribonucleoprotein B''
NM_003092.5	NP_003083.1	U2 small nuclear ribonucleoprotein B''
NM_198220.3	NP_937863.1	U2 small nuclear ribonucleoprotein B''
NM_198220.2	NP_937863.1	U2 small nuclear ribonucleoprotein B''

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	SNRPB2	NP_001238897.1
Mus musculus (house mouse)	Snrpb2	NP_067310.1
Homo sapiens (human)	SNRPB2	NP_003083.1
Gallus gallus (chicken)	SNRPB2	XP_419331.1
Caenorhabditis elegans (roundworm)	rnp-3	NP_500505.1
Xenopus tropicalis (tropical clawed frog)	snrpb2	NP_001011120.1
Pan troglodytes (chimpanzee)	SNRPB2	XP_001137830.1
Bos taurus (cattle)	SNRPB2	NP_001179481.1
Rattus norvegicus (Norway rat)	Snrpb2	NP_001102062.1
Danio rerio (zebrafish)	snrpb2	NP_001243119.1
Arabidopsis thaliana (thale cress)	U2B''	NP_180585.1
Arabidopsis thaliana (thale cress)	AT1G06960	NP_172177.3
	SNRPB2	XP_001086938.1
Oryza sativa (rice)	Os03g0298800	NP_001049846.1

Gene Ontology
Bibliography

Related articles in PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Bertram K, Agafonov DE, Dybkov O, Haselbach D, Leelaram MN, Will CL, Urlaub H, Kastner B, L?hrmann R, Stark H
Cell170(4)701-713.e11(2017 Aug)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Bertram K, Agafonov DE, Liu WT, Dybkov O, Will CL, Hartmuth K, Urlaub H, Kastner B, Stark H, L?hrmann R
Nature542(7641)318-323(2017 02)

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Yachie N, Petsalaki E, Mellor JC, Weile J, Jacob Y, Verby M, Ozturk SB, Li S, Cote AG, Mosca R, Knapp JJ, Ko M, Yu A, Gebbia M, Sahni N, Yi S, Tyagi T, Sheykhkarimli D, Roth JF, Wong C, Musa L, Snider J, Liu YC, Yu H, Braun P, Stagljar I, Hao T, Calderwood MA, Pelletier L, Aloy P, Hill DE, Vidal M, Roth FP
Molecular systems biology12(4)863(2016 Apr)

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Jefferson M, Donaszi-Ivanov A, Pollen S, Dalmay T, Saalbach G, Powell PP
Journal of virology88(18)10340-53(2014 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that protein-protein interactions localize U2A' (SNRPA1) to the U2 snRNP (U2 small nuclear ribonucleoprotein) and exclude it from the U1 snRNP, rather than to enhance U2 snRNA (U2 small nuclear RNA; RNU2-1) binding of U2B'' (SNRPB2).
Title: Binding affinity and cooperativity control U2B?/snRNA/U2A' RNP formation.

The following SNRPB2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SNRPB2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32142	NM_003092.5 Latest version!	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu32142	NM_198220.3 Latest version!	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu32142	NM_003092.4	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu32142	NM_198220.2	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SNRPB2 ( NM_003092.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_003083.1 Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32142
Clone ID Related Accession (Same CDS sequence)	NM_003092.4 , NM_003092.5 , NM_198220.3 , NM_198220.2
Accession Version	NM_003092.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	U2 small nuclear ribonucleoprotein B''
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088017.1, BC018022.1, BM772256.1 and AI741327.1. On Jul 17, 2010 this sequence version replaced NM_003092.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.193633.1, SRR1660807.186971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003083.1
CDS	237..914
Translation	MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK

Target ORF information:

RefSeq Version	NM_003092.4
Organism	Homo sapiens(human)
Definition	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003092.4

ORF Insert Sequence:

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNRPB2 ( NM_003092.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_003083.1 Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32142
Clone ID Related Accession (Same CDS sequence)	NM_003092.4 , NM_003092.5 , NM_198220.3 , NM_198220.2
Accession Version	NM_003092.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	U2 small nuclear ribonucleoprotein B''
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC018022.1, BM772256.1, AI741327.1 and AL034428.4. On Nov 22, 2018 this sequence version replaced NM_003092.4. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.193633.1, SRR3476690.249153.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000246071.8/ ENSP00000246071.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_003083.1
CDS	175..852
Translation	MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK

Target ORF information:

RefSeq Version	NM_003092.5
Organism	Homo sapiens(human)
Definition	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_003092.5

ORF Insert Sequence:

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNRPB2 ( NM_198220.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_937863.1 Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32142
Clone ID Related Accession (Same CDS sequence)	NM_003092.4 , NM_003092.5 , NM_198220.3 , NM_198220.2
Accession Version	NM_198220.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	U2 small nuclear ribonucleoprotein B''
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088017.1, BC036737.3, BM772256.1, AI741327.1 and AL034428.4. On May 31, 2019 this sequence version replaced NM_198220.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.164376.1, SRR3476690.1176981.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937863.1
CDS	75..752
Translation	MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK

Target ORF information:

RefSeq Version	NM_198220.3
Organism	Homo sapiens(human)
Definition	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198220.3

ORF Insert Sequence:

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SNRPB2 ( NM_198220.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_937863.1 Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32142
Clone ID Related Accession (Same CDS sequence)	NM_003092.4 , NM_003092.5 , NM_198220.3 , NM_198220.2
Accession Version	NM_198220.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	U2 small nuclear ribonucleoprotein B''
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA088017.1, BC036737.3, BM772256.1 and AI741327.1. On Jul 17, 2010 this sequence version replaced NM_198220.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.164376.1, SRR3476690.356194.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_937863.1
CDS	137..814
Translation	MDIRPNHTIYINNMNDKIKKEELKRSLYALFSQFGHVVDIVALKTMKMRGQAFVIFKELGSSTNALRQLQGFPFYGKPMRIQYAKTDSDIISKMRGTFADKEKKKEKKKAKTVEQTATTTNKKPGQGTPNSANTQGNSTPNPQVPDYPPNYILFLNNLPEETNEMMLSMLFNQFPGFKEVRLVPGRHDIAFVEFENDGQAGAARDALQGFKITPSHAMKITYAKK

Target ORF information:

RefSeq Version	NM_198220.2
Organism	Homo sapiens(human)
Definition	Homo sapiens small nuclear ribonucleoprotein polypeptide B2 (SNRPB2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_198220.2

ORF Insert Sequence:

ATGGATATCA GACCAAATCA TACAATTTAT ATCAACAATA TGAATGACAA AATTAAAAAG 
GAAGAATTGA AGAGATCCCT ATATGCCCTG TTTTCTCAGT TTGGTCATGT GGTGGACATT 
GTGGCTTTAA AGACCATGAA GATGAGGGGG CAGGCCTTTG TCATATTTAA GGAACTGGGC 
TCATCCACAA ATGCCTTGAG ACAGCTACAA GGATTTCCAT TTTATGGTAA ACCAATGCGA 
ATACAGTATG CAAAAACAGA TTCGGATATA ATATCAAAAA TGCGTGGAAC TTTTGCTGAC 
AAAGAAAAGA AAAAAGAAAA GAAAAAAGCC AAAACTGTGG AACAGACTGC AACAACCACA 
AACAAAAAGC CTGGCCAGGG AACTCCAAAT TCAGCTAATA CCCAAGGAAA TTCAACACCA 
AATCCTCAGG TCCCTGATTA CCCTCCAAAC TATATTTTAT TCCTTAATAA CTTACCAGAA 
GAGACTAATG AGATGATGTT ATCCATGCTG TTTAATCAGT TCCCTGGCTT CAAGGAAGTA 
CGTCTGGTAC CAGGGAGGCA TGACATTGCT TTTGTTGAAT TTGAAAATGA TGGGCAGGCT 
GGAGCTGCCA GGGATGCTTT ACAGGGATTT AAGATCACAC CGTCCCATGC TATGAAGATC 
ACCTATGCCA AGAAATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Cryo-EM Structure of a Pre-catalytic Human Spliceosome Primed for Activation.
Cell170(4)701-713.e11(2017 Aug)
Bertram K,Agafonov DE,Dybkov O,Haselbach D,Leelaram MN,Will CL,Urlaub H,Kastner B,L?hrmann R,Stark H

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

Cryo-EM structure of a human spliceosome activated for step 2 of splicing.
Nature542(7641)318-323(2017 02)
Bertram K,Agafonov DE,Liu WT,Dybkov O,Will CL,Hartmuth K,Urlaub H,Kastner B,Stark H,L?hrmann R

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.
Molecular systems biology12(4)863(2016 Apr)
Yachie N,Petsalaki E,Mellor JC,Weile J,Jacob Y,Verby M,Ozturk SB,Li S,Cote AG,Mosca R,Knapp JJ,Ko M,Yu A,Gebbia M,Sahni N,Yi S,Tyagi T,Sheykhkarimli D,Roth JF,Wong C,Musa L,Snider J,Liu YC,Yu H,Braun P,Stagljar I,Hao T,Calderwood MA,Pelletier L,Aloy P,Hill DE,Vidal M,Roth FP

Host factors that interact with the pestivirus N-terminal protease, Npro, are components of the ribonucleoprotein complex.
Journal of virology88(18)10340-53(2014 Sep)
Jefferson M,Donaszi-Ivanov A,Pollen S,Dalmay T,Saalbach G,Powell PP

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SNRPB2 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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