Gene Symbol | SNAI2 |
Entrez Gene ID | 6591 |
Full Name | snail family transcriptional repressor 2 |
Synonyms | SLUG,SLUGH,SLUGH1,SNAIL2,WS2D |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]. |
Disorder MIM: | |
Disorder Html: | Waardenburg syndrome, type 2D, 608890 (3); Piebaldism, 172800 (3) |