Gene Symbol | RAPH1 |
Entrez Gene ID | 65059 |
Full Name | Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 |
Synonyms | ALS2CR18,ALS2CR9,LPD,PREL-2,PREL2,RMO1,RalGDS/AF-6 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a protein that belongs to the Mig10/Rap1-interacting adaptor molecule/Lamellipodin family of adapter proteins, which function in cell migration. Members of this family contain pleckstrin-homology domains, Ras-association domains, and proline-rich C-termini. The protein encoded by this gene regulates actin dynamics through interaction with Ena/Vasodilator proteins as well as direct binding to filamentous actin to regulate actin network assembly. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]. |
Disorder MIM: |