Gene Symbol | HIF3A |
Entrez Gene ID | 64344 |
Full Name | hypoxia inducible factor 3 alpha subunit |
Synonyms | HIF-3A,HIF3-alpha-1,IPAS,MOP7,PASD7,bHLHe17 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | The protein encoded by this gene is the alpha-3 subunit of one of several alpha/beta-subunit heterodimeric transcription factors that regulate many adaptive responses to low oxygen tension (hypoxia). The alpha-3 subunit lacks the transactivation domain found in factors containing either the alpha-1 or alpha-2 subunits. It is thought that factors containing the alpha-3 subunit are negative regulators of hypoxia-inducible gene expression. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2011]. |
Disorder MIM: |