Gene Symbol | SLC39A8 |
Entrez Gene ID | 64116 |
Full Name | solute carrier family 39 member 8 |
Synonyms | BIGM103,CDG2N,LZT-Hs6,PP3105,ZIP8 |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke. Multiple transcript variants encoding different isoforms have been found for this gene. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Oct 2008]. |
Disorder MIM: | |
Disorder Html: | Congenital disorder of glycosylation, type IIn, 616721 (3) |