TMBIM1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMBIM1
Entrez Gene ID	64114
Full Name	transmembrane BAX inhibitor motif containing 1
Synonyms	LFG3,MST100,MSTP100,PP1201,RECS1
General protein information	Preferred Names transmembrane BAX inhibitor motif containing 1 Names protein lifeguard 3 transmembrane BAX inhibitor motif-containing protein 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 2 Map Location: 2q35
Disorder MIM:	610364

mRNA and Protein(s)

mRNA	Protein	Name
XM_011511627.1	XP_011509929.1	protein lifeguard 3 isoform X1
NM_001321438.1	NP_001308367.1	protein lifeguard 3 isoform 2
NM_001321430.1	NP_001308359.1	protein lifeguard 3 isoform 1
NM_001321428.1	NP_001308357.1	protein lifeguard 3 isoform 1
NM_001321432.1	NP_001308361.1	protein lifeguard 3 isoform 1
NM_022152.6	NP_071435.2	protein lifeguard 3 isoform 1
NM_022152.5	NP_071435.2	protein lifeguard 3 isoform 1
NM_001321436.1	NP_001308365.1	protein lifeguard 3 isoform 1
NM_001321433.1	NP_001308362.1	protein lifeguard 3 isoform 1
NM_001321435.1	NP_001308364.1	protein lifeguard 3 isoform 1
NM_001321427.1	NP_001308356.1	protein lifeguard 3 isoform 1
NM_001321429.1	NP_001308358.1	protein lifeguard 3 isoform 1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMBIM1	XP_005640784.1
Bos taurus (cattle)	TMBIM1	NP_991367.1
Pan troglodytes (chimpanzee)	TMBIM1	XP_001144519.2
	TMBIM1	XP_001089836.1
Rattus norvegicus (Norway rat)	Tmbim1	NP_001007714.1
Danio rerio (zebrafish)	tmbim1	NP_001005992.1
Xenopus tropicalis (tropical clawed frog)	tmbim1	NP_001025668.1
Homo sapiens (human)	TMBIM1	NP_071435.2
Gallus gallus (chicken)	TMBIM1	XP_422067.3
Mus musculus (house mouse)	Tmbim1	NP_081430.3

Gene Ontology
Bibliography

Related articles in PubMed

Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
Zhao GN, Zhang P, Gong J, Zhang XJ, Wang PX, Yin M, Jiang Z, Shen LJ, Ji YX, Tong J, Wang Y, Wei QF, Wang Y, Zhu XY, Zhang X, Fang J, Xie Q, She ZG, Wang Z, Huang Z, Li H
Nature medicine23(6)742-752(2017 Jun)

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Orlando G, Law PJ, Palin K, Tuupanen S, Gylfe A, H?nninen UA, Cajuso T, Tanskanen T, Kondelin J, Kaasinen E, Sarin AP, Kaprio J, Eriksson JG, Rissanen H, Knekt P, Pukkala E, Jousilahti P, Salomaa V, Ripatti S, Palotie A, J?rvinen H, Renkonen-Sinisalo L, Lepist? A, B?hm J, Mecklin JP, Al-Tassan NA, Palles C, Martin L, Barclay E, Tenesa A, Farrington S, Timofeeva MN, Meyer BF, Wakil SM, Campbell H, Smith CG, Idziaszczyk S, Maughan TS, Kaplan R, Kerr R, Kerr D, Buchanan DD, Win AK, Hopper J, Jenkins M, Lindor NM, Newcomb PA, Gallinger S, Conti D, Schumacher F, Casey G, Taipale J, Cheadle JP, Dunlop MG, Tomlinson IP, Aaltonen LA, Houlston RS
Human molecular genetics25(11)2349-2359(2016 06)

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA??-filling state.
Lisak DA, Schacht T, Enders V, Habicht J, Kiviluoto S, Schneider J, Henke N, Bultynck G, Methner A
Biochimica et biophysica acta1853(9)2104-14(2015 Sep)

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Jostins L, Ripke S, Weersma RK, Duerr RH, McGovern DP, Hui KY, Lee JC, Schumm LP, Sharma Y, Anderson CA, Essers J, Mitrovic M, Ning K, Cleynen I, Theatre E, Spain SL, Raychaudhuri S, Goyette P, Wei Z, Abraham C, Achkar JP, Ahmad T, Amininejad L, Ananthakrishnan AN, Andersen V, Andrews JM, Baidoo L, Balschun T, Bampton PA, Bitton A, Boucher G, Brand S, B?ning C, Cohain A, Cichon S, D'Amato M, De Jong D, Devaney KL, Dubinsky M, Edwards C, Ellinghaus D, Ferguson LR, Franchimont D, Fransen K, Gearry R, Georges M, Gieger C, Glas J, Haritunians T, Hart A, Hawkey C, Hedl M, Hu X, Karlsen TH, Kupcinskas L, Kugathasan S, Latiano A, Laukens D, Lawrance IC, Lees CW, Louis E, Mahy G, Mansfield J, Morgan AR, Mowat C, Newman W, Palmieri O, Ponsioen CY, Potocnik U, Prescott NJ, Regueiro M, Rotter JI, Russell RK, Sanderson JD, Sans M, Satsangi J, Schreiber S, Simms LA, Sventoraityte J, Targan SR, Taylor KD, Tremelling M, Verspaget HW, De Vos M, Wijmenga C, Wilson DC, Winkelmann J, Xavier RJ, Zeissig S, Zhang B, Zhang CK, Zhao H, , Silverberg MS, Annese V, Hakonarson H, Brant SR, Radford-Smith G, Mathew CG, Rioux JD, Schadt EE, Daly MJ, Franke A, Parkes M, Vermeire S, Barrett JC, Cho JH
Nature491(7422)119-24(2012 Nov)

A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface.
Shukla S, Fujita K, Xiao Q, Liao Z, Garfield S, Srinivasula SM
Apoptosis : an international journal on programmed cell death16(2)162-73(2011 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

TMBIM1 is an effective suppressor of steatohepatitis and a previously unknown regulator of the multivesicular body (MVB)-lysosomal pathway.
Title: Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.

The combined analysis identified a new risk association for colorectal cancer (CRC) at 2q35 marked by rs992157 which is intronic to PNKD and TMBIM1.Intriguingly this susceptibility single-nucleotide polymorphism (SNP) is in strong linkage disequilibrium (r(2) = 0.90, D' = 0.96) with the previously discovered GWAS SNP rs2382817 for inflammatory bowel disease (IBD).
Title: Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.

These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2) homeostasis in a wide variety of tissues
Title: The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA??-filling state.

data suggest that PP1201 functions as an anti-apoptotic protein and its increased expression in vascular cells can contribute to homeostasis by reducing Fas trafficking to the cell membrane
Title: A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface.

The tmbim1 may participate in cell death regulation by interacting with proteins of Bcl-2 family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments
Title: Comparative genomics and function analysis on BI1 family.

The following TMBIM1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMBIM1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu36525	NM_022152.6 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu03830	NM_001321430.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_022152.5 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321427.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321429.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321435.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 8, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321432.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321436.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 9, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321433.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 7, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu03830	NM_001321428.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu36525	XM_011511627.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
OHu82838	NM_001321438.1 Latest version!	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 10, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMBIM1 ( NM_022152.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_071435.2 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu36525
Clone ID Related Accession (Same CDS sequence)	XM_011511627.1 , NM_022152.6
Accession Version	NM_022152.6 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5. On Nov 23, 2018 this sequence version replaced NM_022152.5. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC013428.1, SRR3476690.261154.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000258412.8/ ENSP00000258412.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCAGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071435.2
CDS	79..1014
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_022152.6
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022152.6

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCAGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321430.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308359.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321430.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.183221.1, SRR1803614.106767.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308359.1
CDS	254..1189
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321430.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321430.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321428.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308357.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321428.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. On Mar 25, 2016 this sequence version replaced XM_005246762.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.32847.1, SRR1163657.311066.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308357.1
CDS	138..1073
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321428.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321428.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321432.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308361.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321432.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.119240.1, SRR1660805.228436.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308361.1
CDS	78..1013
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321432.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321432.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_022152.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_071435.2 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_022152.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-02
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP335035.1, BC013428.1, AC021016.5, AK093911.1 and CA436747.1. On Mar 25, 2016 this sequence version replaced NM_022152.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.210031.1, BC013428.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_071435.2
CDS	153..1088
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_022152.5
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_022152.5

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321436.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308365.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 9, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321436.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. On Mar 25, 2016 this sequence version replaced XM_005246758.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.176486.1, SRR1803613.13176.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308365.1
CDS	329..1264
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321436.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 9, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321436.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321433.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308362.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 7, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321433.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.159440.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308362.1
CDS	251..1186
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321433.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 7, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321433.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321435.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308364.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 8, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321435.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.243926.1, SRR1803614.137493.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348, SAMEA2154405 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308364.1
CDS	325..1260
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321435.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 8, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321435.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321427.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308356.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321427.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-28
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK090618.1, AC021016.5, AK093911.1 and CA436747.1. On Mar 25, 2016 this sequence version replaced XM_011511626.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK090618.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308356.1
CDS	727..1662
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321427.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321427.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321429.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308358.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu03830
Clone ID Related Accession (Same CDS sequence)	NM_001321430.1 , NM_001321428.1 , NM_001321432.1 , NM_022152.5 , NM_001321436.1 , NM_001321433.1 , NM_001321435.1 , NM_001321427.1 , NM_001321429.1
Accession Version	NM_001321429.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-29
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC021016.5, BC013428.1, AK093911.1 and CA436747.1. On Mar 25, 2016 this sequence version replaced XM_011511625.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.686985.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308358.1
CDS	314..1249
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321429.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321429.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCGGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( XM_011511627.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_011509929.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu36525
Clone ID Related Accession (Same CDS sequence)	XM_011511627.1 , NM_022152.6
Accession Version	XM_011511627.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 936bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000002.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCAGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011509929.1
CDS	506..1441
Translation	MSNPSAPPPYEDRNPLYPGPPPPGGYGQPSVLPGGYPAYPGYPQPGYGHPAGYPQPMPPTHPMPMNYGPGHGYDGEERAVSDSFGPGEWDDRKVRHTFIRKVYSIISVQLLITVAIIAIFTFVEPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	XM_011511627.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011511627.1

ORF Insert Sequence:

ATGTCCAACC CCAGCGCCCC ACCACCATAT GAAGACCGCA ACCCCCTGTA CCCAGGCCCT 
CCGCCCCCTG GGGGCTATGG GCAGCCATCT GTCCTGCCAG GAGGGTATCC TGCCTACCCT 
GGCTACCCGC AGCCTGGCTA CGGTCACCCT GCTGGCTACC CACAGCCCAT GCCCCCCACC 
CACCCGATGC CCATGAACTA CGGCCCAGGC CATGGCTATG ATGGGGAGGA GAGAGCAGTG 
AGTGATAGCT TCGGGCCTGG AGAGTGGGAT GACCGGAAAG TGCGACACAC TTTTATCCGA 
AAGGTTTACT CCATCATCTC CGTGCAGCTG CTCATCACTG TGGCCATCAT TGCTATCTTC 
ACCTTTGTGG AACCTGTCAG CGCCTTTGTG AGGAGAAATG TGGCTGTCTA CTACGTGTCC 
TATGCTGTCT TCGTTGTCAC CTACCTGATC CTTGCCTGCT GCCAGGGACC CAGACGCCGT 
TTCCCATGGA ACATCATTCT GCTGACCCTT TTTACTTTTG CCATGGGCTT CATGACGGGC 
ACCATTTCCA GTATGTACCA AACCAAAGCC GTCATCATTG CAATGATCAT CACTGCGGTG 
GTATCCATTT CAGTCACCAT CTTCTGCTTT CAGACCAAGG TGGACTTCAC CTCGTGCACA 
GGCCTCTTCT GTGTCCTGGG AATTGTGCTC CTGGTGACTG GGATTGTCAC TAGCATTGTG 
CTCTACTTCC AATACGTTTA CTGGCTCCAC ATGCTCTATG CTGCTCTGGG GGCCATTTGT 
TTCACCCTGT TCCTGGCTTA CGACACACAG CTGGTCCTGG GGAACCGGAA GCACACCATC 
AGCCCCGAGG ACTACATCAC TGGCGCCCTG CAGATTTACA CAGACATCAT CTACATCTTC 
ACCTTTGTGC TGCAGCTGAT GGGGGATCGC AATTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMBIM1 ( NM_001321438.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001308367.1 Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 10, mRNA.

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CloneID	OHu82838
Clone ID Related Accession (Same CDS sequence)	NM_001321438.1
Accession Version	NM_001321438.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 603bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Homo sapiens(human)
Product	protein lifeguard 3 isoform 2
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP335035.1, AK300597.1, AC021016.5, AK093911.1 and CA436747.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK300597.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154405, SAMEA2467146 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGACCGGAA AGTGCGACAC ACTTTTATCC GAAAGGGAAC CTGTCAGCGC CTTTGTGAGG 
AGAAATGTGG CTGTCTACTA CGTGTCCTAT GCTGTCTTCG TTGTCACCTA CCTGATCCTT 
GCCTGCTGCC AGGGACCCAG ACGCCGTTTC CCATGGAACA TCATTCTGCT GACCCTTTTT 
ACTTTTGCCA TGGGCTTCAT GACGGGCACC ATTTCCAGTA TGTACCAAAC CAAAGCCGTC 
ATCATTGCAA TGATCATCAC TGCGGTGGTA TCCATTTCAG TCACCATCTT CTGCTTTCAG 
ACCAAGGTGG ACTTCACCTC GTGCACAGGC CTCTTCTGTG TCCTGGGAAT TGTGCTCCTG 
GTGACTGGGA TTGTCACTAG CATTGTGCTC TACTTCCAAT ACGTTTACTG GCTCCACATG 
CTCTATGCTG CTCTGGGGGC CATTTGTTTC ACCCTGTTCC TGGCTTACGA CACACAGCTG 
GTCCTGGGGA ACCGGAAGCA CACCATCAGC CCCGAGGACT ACATCACTGG CGCCCTGCAG 
ATTTACACAG ACATCATCTA CATCTTCACC TTTGTGCTGC AGCTGATGGG GGATCGCAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001308367.1
CDS	421..1023
Translation	MTGKCDTLLSEREPVSAFVRRNVAVYYVSYAVFVVTYLILACCQGPRRRFPWNIILLTLFTFAMGFMTGTISSMYQTKAVIIAMIITAVVSISVTIFCFQTKVDFTSCTGLFCVLGIVLLVTGIVTSIVLYFQYVYWLHMLYAALGAICFTLFLAYDTQLVLGNRKHTISPEDYITGALQIYTDIIYIFTFVLQLMGDRN

Target ORF information:

RefSeq Version	NM_001321438.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane BAX inhibitor motif containing 1 (TMBIM1), transcript variant 10, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001321438.1

ORF Insert Sequence:

ATGACCGGAA AGTGCGACAC ACTTTTATCC GAAAGGGAAC CTGTCAGCGC CTTTGTGAGG 
AGAAATGTGG CTGTCTACTA CGTGTCCTAT GCTGTCTTCG TTGTCACCTA CCTGATCCTT 
GCCTGCTGCC AGGGACCCAG ACGCCGTTTC CCATGGAACA TCATTCTGCT GACCCTTTTT 
ACTTTTGCCA TGGGCTTCAT GACGGGCACC ATTTCCAGTA TGTACCAAAC CAAAGCCGTC 
ATCATTGCAA TGATCATCAC TGCGGTGGTA TCCATTTCAG TCACCATCTT CTGCTTTCAG 
ACCAAGGTGG ACTTCACCTC GTGCACAGGC CTCTTCTGTG TCCTGGGAAT TGTGCTCCTG 
GTGACTGGGA TTGTCACTAG CATTGTGCTC TACTTCCAAT ACGTTTACTG GCTCCACATG 
CTCTATGCTG CTCTGGGGGC CATTTGTTTC ACCCTGTTCC TGGCTTACGA CACACAGCTG 
GTCCTGGGGA ACCGGAAGCA CACCATCAGC CCCGAGGACT ACATCACTGG CGCCCTGCAG 
ATTTACACAG ACATCATCTA CATCTTCACC TTTGTGCTGC AGCTGATGGG GGATCGCAAT 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Tmbim1 is a multivesicular body regulator that protects against non-alcoholic fatty liver disease in mice and monkeys by targeting the lysosomal degradation of Tlr4.
Nature medicine23(6)742-752(2017 Jun)
Zhao GN,Zhang P,Gong J,Zhang XJ,Wang PX,Yin M,Jiang Z,Shen LJ,Ji YX,Tong J,Wang Y,Wei QF,Wang Y,Zhu XY,Zhang X,Fang J,Xie Q,She ZG,Wang Z,Huang Z,Li H

Variation at 2q35 (PNKD and TMBIM1) influences colorectal cancer risk and identifies a pleiotropic effect with inflammatory bowel disease.
Human molecular genetics25(11)2349-2359(2016 06)
Orlando G,Law PJ,Palin K,Tuupanen S,Gylfe A,H?nninen UA,Cajuso T,Tanskanen T,Kondelin J,Kaasinen E,Sarin AP,Kaprio J,Eriksson JG,Rissanen H,Knekt P,Pukkala E,Jousilahti P,Salomaa V,Ripatti S,Palotie A,J?rvinen H,Renkonen-Sinisalo L,Lepist? A,B?hm J,Mecklin JP,Al-Tassan NA,Palles C,Martin L,Barclay E,Tenesa A,Farrington S,Timofeeva MN,Meyer BF,Wakil SM,Campbell H,Smith CG,Idziaszczyk S,Maughan TS,Kaplan R,Kerr R,Kerr D,Buchanan DD,Win AK,Hopper J,Jenkins M,Lindor NM,Newcomb PA,Gallinger S,Conti D,Schumacher F,Casey G,Taipale J,Cheadle JP,Dunlop MG,Tomlinson IP,Aaltonen LA,Houlston RS

The transmembrane Bax inhibitor motif (TMBIM) containing protein family: Tissue expression, intracellular localization and effects on the ER CA??-filling state.
Biochimica et biophysica acta1853(9)2104-14(2015 Sep)
Lisak DA,Schacht T,Enders V,Habicht J,Kiviluoto S,Schneider J,Henke N,Bultynck G,Methner A

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.
Nature491(7422)119-24(2012 Nov)
Jostins L,Ripke S,Weersma RK,Duerr RH,McGovern DP,Hui KY,Lee JC,Schumm LP,Sharma Y,Anderson CA,Essers J,Mitrovic M,Ning K,Cleynen I,Theatre E,Spain SL,Raychaudhuri S,Goyette P,Wei Z,Abraham C,Achkar JP,Ahmad T,Amininejad L,Ananthakrishnan AN,Andersen V,Andrews JM,Baidoo L,Balschun T,Bampton PA,Bitton A,Boucher G,Brand S,B?ning C,Cohain A,Cichon S,D'Amato M,De Jong D,Devaney KL,Dubinsky M,Edwards C,Ellinghaus D,Ferguson LR,Franchimont D,Fransen K,Gearry R,Georges M,Gieger C,Glas J,Haritunians T,Hart A,Hawkey C,Hedl M,Hu X,Karlsen TH,Kupcinskas L,Kugathasan S,Latiano A,Laukens D,Lawrance IC,Lees CW,Louis E,Mahy G,Mansfield J,Morgan AR,Mowat C,Newman W,Palmieri O,Ponsioen CY,Potocnik U,Prescott NJ,Regueiro M,Rotter JI,Russell RK,Sanderson JD,Sans M,Satsangi J,Schreiber S,Simms LA,Sventoraityte J,Targan SR,Taylor KD,Tremelling M,Verspaget HW,De Vos M,Wijmenga C,Wilson DC,Winkelmann J,Xavier RJ,Zeissig S,Zhang B,Zhang CK,Zhao H,,Silverberg MS,Annese V,Hakonarson H,Brant SR,Radford-Smith G,Mathew CG,Rioux JD,Schadt EE,Daly MJ,Franke A,Parkes M,Vermeire S,Barrett JC,Cho JH

A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface.
Apoptosis : an international journal on programmed cell death16(2)162-73(2011 Feb)
Shukla S,Fujita K,Xiao Q,Liao Z,Garfield S,Srinivasula SM

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TMBIM1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

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ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム