RGS13 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	RGS13
Entrez Gene ID	6003
Full Name	regulator of G protein signaling 13
General protein information	Preferred Names regulator of G protein signaling 13 Names regulator of G-protein signaling 13 regulator of G-protein signalling 13
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q31.2
Summary	The protein encoded by this gene is a member of the regulator of G protein signaling (RGS) family. RGS family members share similarity with S. cerevisiae SST2 and C. elegans egl-10 proteins, which contain a characteristic conserved RGS domain. RGS proteins accelerate GTPase activity of G protein alpha-subunits, thereby driving G protein into their inactive GDP-bound form, thus negatively regulating G protein signaling. RGS proteins have been implicated in the fine tuning of a variety of cellular events in response to G protein-coupled receptor activation. The biological function of this gene, however, is unknown. Two transcript variants encoding the same isoform exist. [provided by RefSeq, Jul 2008].
Disorder MIM:	607190

mRNA and Protein(s)

mRNA	Protein	Name
NM_002927.4	NP_002918.1	regulator of G-protein signaling 13
NM_144766.3	NP_658912.1	regulator of G-protein signaling 13
NM_002927.5	NP_002918.1	regulator of G-protein signaling 13
NM_144766.2	NP_658912.1	regulator of G-protein signaling 13

Pathways from BioSystems

Homologies

	LOC712688	XP_001112849.1
Mus musculus (house mouse)	Rgs13	NP_694811.1
Homo sapiens (human)	RGS13	NP_658912.1
Rattus norvegicus (Norway rat)	Rgs13	XP_573469.3
Canis lupus familiaris (dog)	RGS13	XP_005640874.1
Xenopus tropicalis (tropical clawed frog)	rgs13	XP_002939125.2
Pan troglodytes (chimpanzee)	RGS13	XP_001166458.1
Gallus gallus (chicken)	RGS13	XP_004943195.1

Gene Ontology
Bibliography

Related articles in PubMed

p53 negatively regulates RGS13 protein expression in immune cells.
Iwaki S, Lu Y, Xie Z, Druey KM
The Journal of biological chemistry286(25)22219-26(2011 Jun)

Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.
Xie Z, Yang Z, Druey KM
Journal of molecular cell biology2(6)357-65(2010 Dec)

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.
Wang J, Lippman SM, Lee JJ, Yang H, Khuri FR, Kim E, Lin J, Chang DW, Lotan R, Hong WK, Wu X
Carcinogenesis31(10)1755-61(2010 Oct)

Association study of 182 candidate genes in anorexia nervosa.
Pinheiro AP, Bulik CM, Thornton LM, Sullivan PF, Root TL, Bloss CS, Berrettini WH, Schork NJ, Kaye WH, Bergen AW, Magistretti P, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel PK, Klump KL, La Via M, Mitchell JE, Strober M, Rotondo A, Treasure J, Woodside DB
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(5)1070-80(2010 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

p53 may modulate immune responses through suppression of RGS13 transcription in mast cells and B cells
Title: p53 negatively regulates RGS13 protein expression in immune cells.

RGS13 turnover was significantly reduced in cells stimulated with cAMP, which was reversed by expression of the PKA-specific inhibitory peptide PKI.
Title: Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.

Observational study of gene-disease association. (HuGE Navigator)
Title: Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association study of 182 candidate genes in anorexia nervosa.

RGS13 overexpression inhibited CXCL12-evoked Ca(2+) mobilization, Akt phosphorylation and chemotaxis.
Title: RGS13 controls g protein-coupled receptor-evoked responses of human mast cells.

The following RGS13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RGS13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu32306	NM_002927.5 Latest version!	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu32306	NM_144766.3 Latest version!	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu32306	NM_002927.4	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu32306	NM_144766.2	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RGS13 ( NM_002927.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_002918.1 Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32306
Clone ID Related Accession (Same CDS sequence)	NM_002927.4 , NM_144766.3 , NM_002927.5 , NM_144766.2
Accession Version	NM_002927.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU942880.1 and BC056866.1. On Dec 18, 2010 this sequence version replaced NM_002927.3. Transcript Variant: This variant (1) represents the longer transcript. ##Evidence-Data-START## Transcript exon combination :: BC056866.1, AF030107.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002918.1
CDS	296..775
Translation	MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF

Target ORF information:

RefSeq Version	NM_002927.4
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002927.4

ORF Insert Sequence:

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS13 ( NM_144766.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_658912.1 Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32306
Clone ID Related Accession (Same CDS sequence)	NM_002927.4 , NM_144766.3 , NM_002927.5 , NM_144766.2
Accession Version	NM_144766.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-01
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL596119.5 and AL136454.6. On Mar 29, 2019 this sequence version replaced NM_144766.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016667.1, AL582920.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_658912.1
CDS	247..726
Translation	MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF

Target ORF information:

RefSeq Version	NM_144766.3
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144766.3

ORF Insert Sequence:

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS13 ( NM_002927.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_002918.1 Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu32306
Clone ID Related Accession (Same CDS sequence)	NM_002927.4 , NM_144766.3 , NM_002927.5 , NM_144766.2
Accession Version	NM_002927.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL596119.5 and AL136454.6. On Mar 29, 2019 this sequence version replaced NM_002927.4. Transcript Variant: This variant (1) represents the longer transcript. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF030107.2, SRR5189667.188565.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002918.1
CDS	287..766
Translation	MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF

Target ORF information:

RefSeq Version	NM_002927.5
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002927.5

ORF Insert Sequence:

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RGS13 ( NM_144766.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_658912.1 Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu32306
Clone ID Related Accession (Same CDS sequence)	NM_002927.4 , NM_144766.3 , NM_002927.5 , NM_144766.2
Accession Version	NM_144766.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 480bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-24
Organism	Homo sapiens(human)
Product	regulator of G-protein signaling 13
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BU942880.1, BC016667.1 and BC056866.1. On Dec 18, 2010 this sequence version replaced NM_144766.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same isoform. ##Evidence-Data-START## Transcript exon combination :: BC016667.1, AL582920.3 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_658912.1
CDS	256..735
Translation	MSRRNCWICKMCRDESKRPPSNLTLEEVLQWAQSFENLMATKYGPVVYAAYLKMEHSDENIQFWMACETYKKIASRWSRISRAKKLYKIYIQPQSPREINIDSSTRETIIRNIQEPTETCFEEAQKIVYMHMERDSYPRFLKSEMYQKLLKTMQSNNSF

Target ORF information:

RefSeq Version	NM_144766.2
Organism	Homo sapiens(human)
Definition	Homo sapiens regulator of G protein signaling 13 (RGS13), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_144766.2

ORF Insert Sequence:

ATGAGCAGGC GGAATTGTTG GATTTGTAAG ATGTGCAGAG ATGAATCTAA GAGGCCCCCT 
TCAAACCTTA CTTTGGAGGA AGTATTACAG TGGGCCCAGT CTTTTGAAAA TTTAATGGCT 
ACAAAATATG GTCCAGTAGT CTATGCAGCA TATTTAAAAA TGGAGCACAG TGACGAGAAT 
ATTCAATTCT GGATGGCATG TGAAACCTAT AAGAAAATTG CCTCACGGTG GAGCAGAATT 
TCTAGGGCAA AGAAGCTTTA TAAGATTTAC ATCCAGCCAC AGTCCCCTAG AGAGATTAAC 
ATTGACAGTT CGACAAGAGA GACTATCATC AGGAACATTC AGGAACCCAC TGAAACATGT 
TTTGAAGAAG CTCAGAAAAT AGTCTATATG CATATGGAAA GGGATTCCTA CCCCAGATTT 
CTAAAGTCAG AAATGTACCA AAAACTTTTG AAAACTATGC AGTCCAACAA CAGTTTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

p53 negatively regulates RGS13 protein expression in immune cells.
The Journal of biological chemistry286(25)22219-26(2011 Jun)
Iwaki S,Lu Y,Xie Z,Druey KM

Phosphorylation of RGS13 by the cyclic AMP-dependent protein kinase inhibits RGS13 degradation.
Journal of molecular cell biology2(6)357-65(2010 Dec)
Xie Z,Yang Z,Druey KM

Genetic variations in regulator of G-protein signaling genes as susceptibility loci for second primary tumor/recurrence in head and neck squamous cell carcinoma.
Carcinogenesis31(10)1755-61(2010 Oct)
Wang J,Lippman SM,Lee JJ,Yang H,Khuri FR,Kim E,Lin J,Chang DW,Lotan R,Hong WK,Wu X

Association study of 182 candidate genes in anorexia nervosa.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics153B(5)1070-80(2010 Jul)
Pinheiro AP,Bulik CM,Thornton LM,Sullivan PF,Root TL,Bloss CS,Berrettini WH,Schork NJ,Kaye WH,Bergen AW,Magistretti P,Brandt H,Crawford S,Crow S,Fichter MM,Goldman D,Halmi KA,Johnson C,Kaplan AS,Keel PK,Klump KL,La Via M,Mitchell JE,Strober M,Rotondo A,Treasure J,Woodside DB

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RGS13 cDNA ORF clone, Homo sapiens(human)

Gene

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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