Gene Symbol | RARA |
Entrez Gene ID | 5914 |
Full Name | retinoic acid receptor alpha |
Synonyms | NR1B1,RAR |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene represents a nuclear retinoic acid receptor. The encoded protein, retinoic acid receptor alpha, regulates transcription in a ligand-dependent manner. This gene has been implicated in regulation of development, differentiation, apoptosis, granulopoeisis, and transcription of clock genes. Translocations between this locus and several other loci have been associated with acute promyelocytic leukemia. Alternatively spliced transcript variants have been found for this locus.[provided by RefSeq, Sep 2010]. |
Disorder MIM: | |
Disorder Html: | Leukemia, acute promyelocytic, 612376 (1) |