Gene Symbol | JAM2 |
Entrez Gene ID | 58494 |
Full Name | junctional adhesion molecule 2 |
Synonyms | C21orf43,CD322,JAM-B,JAMB,PRO245,VE-JAM,VEJAM |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene belongs to the immunoglobulin superfamily, and the junctional adhesion molecule (JAM) family. The protein encoded by this gene is a type I membrane protein that is localized at the tight junctions of both epithelial and endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types, and may play a role in lymphocyte homing to secondary lymphoid organs. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2012]. |
Disorder MIM: |