STIM2 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	STIM2
Entrez Gene ID	57620
Full Name	stromal interaction molecule 2
General protein information	Preferred Names stromal interaction molecule 2 Names stromal interaction molecule 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 4 Map Location: 4p15.2
Summary	This gene is a member of the stromal interaction molecule (STIM) family and likely arose, along with related family member STIM1, from a common ancestral gene. The encoded protein functions to regulate calcium concentrations in the cytosol and endoplasmic reticulum, and is involved in the activation of plasma membrane Orai Ca(2+) entry channels. This gene initiates translation from a non-AUG (UUG) start site. A signal peptide is cleaved from the resulting protein. Multiple transcript variants result from alternative splicing. [provided by RefSeq, Dec 2009].
Disorder MIM:	610841

mRNA and Protein(s)

mRNA	Protein	Name
NM_001169117.2	NP_001162588.1	stromal interaction molecule 2 isoform 3 precursor
NM_001169118.1	NP_001162589.1	stromal interaction molecule 2 isoform 1 precursor
NM_001169117.1	NP_001162588.1	stromal interaction molecule 2 isoform 3 precursor
NM_001169118.2	NP_001162589.1	stromal interaction molecule 2 isoform 1 precursor
NM_020860.3	NP_065911.3	stromal interaction molecule 2 isoform 2 precursor
NM_020860.4	NP_065911.3	stromal interaction molecule 2 isoform 2 precursor

Pathways from BioSystems

Homologies

Homo sapiens (human)	STIM2	NP_001162589.1
Rattus norvegicus (Norway rat)	Stim2	NP_001099220.2
Gallus gallus (chicken)	STIM2	XP_420749.4
Danio rerio (zebrafish)	stim2b	XP_692356.4
Mus musculus (house mouse)	Stim2	NP_001074572.2
Pan troglodytes (chimpanzee)	STIM2	XP_001166846.1
	STIM2	XP_001084785.2
Canis lupus familiaris (dog)	STIM2	XP_005618705.1
Bos taurus (cattle)	STIM2	XP_002688207.2
Xenopus tropicalis (tropical clawed frog)	stim2	XP_004916816.1

Gene Ontology
Bibliography

Related articles in PubMed

STIM1 and STIM2 differently regulate endogenous Ca
Zhang S, Miao Y, Zheng X, Gong Y, Zhang J, Zou F, Cai C
Biochemical and biophysical research communications488(1)74-80(2017 06)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The STIM2 protein play important roles in TGF-beta-induced EMT and these effects are related to both store-operated calcium entry and non-store-operated calcium entry.
Title: STIM1 and STIM2 differently regulate endogenous Ca

What is less clear is how the spatial and temporal spread of intracellular Ca(2+) is shaped and regulated by differential expression of the individual SOCE genes and their splice variants, their heteromeric combinations and pre- and posttranslational modifications. This review focuses on principle mechanisms regulating expression, splicing, and targeting of Ca(2+) release-activated Ca(2+) (CRAC) channels.
Title: Changing calcium: CRAC channel (STIM and Orai) expression, splicing, and posttranslational modifiers.

STIM2beta does not by itself strongly bind Orai1, it is recruited to Orai1 channels by forming heterodimers with other STIM isoforms.
Title: Alternative splicing converts STIM2 from an activator to an inhibitor of store-operated calcium channels.

STIM2.1 cannot activate Orai1 due to splicing in residues within the channel-activating domain (CAD). STIM2.1 confers a calcium dependent dominant-negative function on both STIM1 and STIM2 (STIM2.2). Affinity of the STIM2.1 calmodulin binding site within the CAD domain is increased compared to STIM2.2.
Title: A STIM2 splice variant negatively regulates store-operated calcium entry.

STIM2 enhances receptor-stimulated Ca(2) signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.
Title: STIM2 enhances receptor-stimulated Ca?? signaling by promoting recruitment of STIM1 to the endoplasmic reticulum-plasma membrane junctions.

The following STIM2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STIM2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu13686	NM_001169118.1 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu13694	NM_001169117.1 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$265.30 $379.00
OHu13655	NM_020860.3 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$524.30 $749.00
OHu108562	NM_001169117.2 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
OHu108563	NM_001169118.2 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00
OHu108566	NM_020860.4 Latest version!	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STIM2 ( NM_001169118.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162589.1 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu13686
Clone ID Related Accession (Same CDS sequence)	NM_001169118.1
Accession Version	NM_001169118.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-22
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF328905.1, AK096846.1 and AB040915.1. Transcript Variant: This variant (1, also known as STIM2.1 or STIM2beta) encodes the longest isoform (1). This isoform functions as a negative regulator of store-operated calcium entry (SOCE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC136449.1, SRR1660805.25422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG TTGCTGCTTC ATATCTGATT CAGGCAGAAA AAATTAAAAA GAAGAGAAGC 
ACAGTCTTTG GGACTCTGCA CGTTGCACAC AGCTCCTCCC TAGATGAGGT AGACCACAAA 
ATTCTGGAAG CAAAGAAAGC TCTCTCTGAG TTGACAACTT GTTTACGAGA ACGACTTTTT 
CGCTGGCAAC AAATTGAGAA GATCTGTGGC TTTCAGATAG CCCATAACTC AGGACTCCCC 
AGCCTGACCT CTTCCCTTTA TTCTGATCAC AGCTGGGTGG TGATGCCCAG AGTCTCCATT 
CCACCCTATC CAATTGCTGG AGGAGTTGAT GACTTAGATG AAGACACACC CCCAATAGTG 
TCACAATTTC CCGGGACCAT GGCTAAACCT CCTGGATCAT TAGCCAGAAG CAGCAGCCTG 
TGCCGTTCAC GCCGCAGCAT TGTGCCGTCC TCGCCTCAGC CTCAGCGAGC TCAGCTTGCT 
CCACACGCCC CCCACCCGTC ACACCCTCGG CACCCTCACC ACCCGCAACA CACACCACAC 
TCCTTGCCTT CCCCTGATCC AGATATCCTC TCAGTGTCAA GTTGCCCTGC GCTTTATCGA 
AATGAAGAGG AGGAAGAGGC CATTTACTTC TCTGCTGAAA AGCAATGGGA AGTGCCAGAC 
ACAGCTTCAG AATGTGACTC CTTAAATTCT TCCATTGGAA GGAAACAGTC TCCTCCTTTA 
AGCCTCGAGA TATACCAAAC ATTATCTCCG CGAAAGATAT CAAGAGATGA GGTGTCCCTA 
GAGGATTCCT CCCGAGGGGA TTCGCCTGTA ACTGTGGATG TGTCTTGGGG TTCTCCCGAC 
TGTGTAGGTC TGACAGAAAC TAAGAGTATG ATCTTCAGTC CTGCAAGCAA AGTGTACAAT 
GGCATTTTGG AGAAATCCTG TAGCATGAAC CAGCTTTCCA GTGGCATCCC GGTGCCTAAA 
CCTCGCCACA CATCATGTTC CTCAGCTGGC AACGACAGTA AACCAGTTCA GGAAGCCCCA 
AGTGTTGCCA GAATAAGCAG CATCCCACAT GACCTTTGTC ATAATGGAGA GAAAAGCAAA 
AAGCCATCAA AAATCAAAAG CCTTTTTAAG AAGAAATCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162589.1
CDS	529..2793
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEVAASYLIQAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSPPLSLEIYQTLSPRKISRDEVSLEDSSRGDSPVTVDVSWGSPDCVGLTETKSMIFSPASKVYNGILEKSCSMNQLSSGIPVPKPRHTSCSSAGNDSKPVQEAPSVARISSIPHDLCHNGEKSKKPSKIKSLFKKKSK

Target ORF information:

RefSeq Version	NM_001169118.1
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169118.1

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG TTGCTGCTTC ATATCTGATT CAGGCAGAAA AAATTAAAAA GAAGAGAAGC 
ACAGTCTTTG GGACTCTGCA CGTTGCACAC AGCTCCTCCC TAGATGAGGT AGACCACAAA 
ATTCTGGAAG CAAAGAAAGC TCTCTCTGAG TTGACAACTT GTTTACGAGA ACGACTTTTT 
CGCTGGCAAC AAATTGAGAA GATCTGTGGC TTTCAGATAG CCCATAACTC AGGACTCCCC 
AGCCTGACCT CTTCCCTTTA TTCTGATCAC AGCTGGGTGG TGATGCCCAG AGTCTCCATT 
CCACCCTATC CAATTGCTGG AGGAGTTGAT GACTTAGATG AAGACACACC CCCAATAGTG 
TCACAATTTC CCGGGACCAT GGCTAAACCT CCTGGATCAT TAGCCAGAAG CAGCAGCCTG 
TGCCGTTCAC GCCGCAGCAT TGTGCCGTCC TCGCCTCAGC CTCAGCGAGC TCAGCTTGCT 
CCACACGCCC CCCACCCGTC ACACCCTCGG CACCCTCACC ACCCGCAACA CACACCACAC 
TCCTTGCCTT CCCCTGATCC AGATATCCTC TCAGTGTCAA GTTGCCCTGC GCTTTATCGA 
AATGAAGAGG AGGAAGAGGC CATTTACTTC TCTGCTGAAA AGCAATGGGA AGTGCCAGAC 
ACAGCTTCAG AATGTGACTC CTTAAATTCT TCCATTGGAA GGAAACAGTC TCCTCCTTTA 
AGCCTCGAGA TATACCAAAC ATTATCTCCG CGAAAGATAT CAAGAGATGA GGTGTCCCTA 
GAGGATTCCT CCCGAGGGGA TTCGCCTGTA ACTGTGGATG TGTCTTGGGG TTCTCCCGAC 
TGTGTAGGTC TGACAGAAAC TAAGAGTATG ATCTTCAGTC CTGCAAGCAA AGTGTACAAT 
GGCATTTTGG AGAAATCCTG TAGCATGAAC CAGCTTTCCA GTGGCATCCC GGTGCCTAAA 
CCTCGCCACA CATCATGTTC CTCAGCTGGC AACGACAGTA AACCAGTTCA GGAAGCCCCA 
AGTGTTGCCA GAATAAGCAG CATCCCACAT GACCTTTGTC ATAATGGAGA GAAAAGCAAA 
AAGCCATCAA AAATCAAAAG CCTTTTTAAG AAGAAATCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM2 ( NM_001169117.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162588.1 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu13694
Clone ID Related Accession (Same CDS sequence)	NM_001169117.1
Accession Version	NM_001169117.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF328905.1, AK096846.1, BC146661.1 and AB040915.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, and differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC146661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGTATTCAC CTTGGGCTCG GTGCGTGCAA AAGTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162588.1
CDS	529..2328
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQCIHLGLGACKSE

Target ORF information:

RefSeq Version	NM_001169117.1
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169117.1

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGTATTCAC CTTGGGCTCG GTGCGTGCAA AAGTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM2 ( NM_020860.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_065911.3 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu13655
Clone ID Related Accession (Same CDS sequence)	NM_020860.3
Accession Version	NM_020860.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-21
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AF328905.1, AK096846.1 and AB040915.1. On Dec 15, 2009 this sequence version replaced NM_020860.2. Transcript Variant: This variant (2, also known as STIM2.2 or STIM2alpha) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. This isoform functions as a positive regulator of store-operated calcium entry (SOCE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB040915.1, AF328905.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGGGAAGTG CCAGACACAG CTTCAGAATG TGACTCCTTA 
AATTCTTCCA TTGGAAGGAA ACAGTCTCCT CCTTTAAGCC TCGAGATATA CCAAACATTA 
TCTCCGCGAA AGATATCAAG AGATGAGGTG TCCCTAGAGG ATTCCTCCCG AGGGGATTCG 
CCTGTAACTG TGGATGTGTC TTGGGGTTCT CCCGACTGTG TAGGTCTGAC AGAAACTAAG 
AGTATGATCT TCAGTCCTGC AAGCAAAGTG TACAATGGCA TTTTGGAGAA ATCCTGTAGC 
ATGAACCAGC TTTCCAGTGG CATCCCGGTG CCTAAACCTC GCCACACATC ATGTTCCTCA 
GCTGGCAACG ACAGTAAACC AGTTCAGGAA GCCCCAAGTG TTGCCAGAAT AAGCAGCATC 
CCACATGACC TTTGTCATAA TGGAGAGAAA AGCAAAAAGC CATCAAAAAT CAAAAGCCTT 
TTTAAGAAGA AATCTAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065911.3
CDS	529..2769
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSPPLSLEIYQTLSPRKISRDEVSLEDSSRGDSPVTVDVSWGSPDCVGLTETKSMIFSPASKVYNGILEKSCSMNQLSSGIPVPKPRHTSCSSAGNDSKPVQEAPSVARISSIPHDLCHNGEKSKKPSKIKSLFKKKSK

Target ORF information:

RefSeq Version	NM_020860.3
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020860.3

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAAGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGGGAAGTG CCAGACACAG CTTCAGAATG TGACTCCTTA 
AATTCTTCCA TTGGAAGGAA ACAGTCTCCT CCTTTAAGCC TCGAGATATA CCAAACATTA 
TCTCCGCGAA AGATATCAAG AGATGAGGTG TCCCTAGAGG ATTCCTCCCG AGGGGATTCG 
CCTGTAACTG TGGATGTGTC TTGGGGTTCT CCCGACTGTG TAGGTCTGAC AGAAACTAAG 
AGTATGATCT TCAGTCCTGC AAGCAAAGTG TACAATGGCA TTTTGGAGAA ATCCTGTAGC 
ATGAACCAGC TTTCCAGTGG CATCCCGGTG CCTAAACCTC GCCACACATC ATGTTCCTCA 
GCTGGCAACG ACAGTAAACC AGTTCAGGAA GCCCCAAGTG TTGCCAGAAT AAGCAGCATC 
CCACATGACC TTTGTCATAA TGGAGAGAAA AGCAAAAAGC CATCAAAAAT CAAAAGCCTT 
TTTAAGAAGA AATCTAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM2 ( NM_001169117.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162588.1 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu108562
Clone ID Related Accession (Same CDS sequence)	NM_001169117.2
Accession Version	NM_001169117.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1800bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 3 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106047.5 and AC006928.15. On Jun 2, 2019 this sequence version replaced NM_001169117.1. Transcript Variant: This variant (3) lacks an alternate in-frame exon in the central coding region, and differs in the 3' coding region and 3' UTR, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is shorter than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC152554.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2154665, SAMEA2157437 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGTATTCAC CTTGGGCTCG GTGCGTGCAA AAGTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162588.1
CDS	379..2178
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQCIHLGLGACKSE

Target ORF information:

RefSeq Version	NM_001169117.2
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169117.2

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGTATTCAC CTTGGGCTCG GTGCGTGCAA AAGTGAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM2 ( NM_001169118.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001162589.1 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu108563
Clone ID Related Accession (Same CDS sequence)	NM_001169118.2
Accession Version	NM_001169118.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2265bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106047.5 and AC006928.15. On Jun 2, 2019 this sequence version replaced NM_001169118.1. Transcript Variant: This variant (1, also known as STIM2.1 or STIM2beta) encodes the longest isoform (1). This isoform functions as a negative regulator of store-operated calcium entry (SOCE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK096846.1, SRR1660805.25422.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG TTGCTGCTTC ATATCTGATT CAGGCAGAAA AAATTAAAAA GAAGAGAAGC 
ACAGTCTTTG GGACTCTGCA CGTTGCACAC AGCTCCTCCC TAGATGAGGT AGACCACAAA 
ATTCTGGAAG CAAAGAAAGC TCTCTCTGAG TTGACAACTT GTTTACGAGA ACGACTTTTT 
CGCTGGCAAC AAATTGAGAA GATCTGTGGC TTTCAGATAG CCCATAACTC AGGACTCCCC 
AGCCTGACCT CTTCCCTTTA TTCTGATCAC AGCTGGGTGG TGATGCCCAG AGTCTCCATT 
CCACCCTATC CAATTGCTGG AGGAGTTGAT GACTTAGATG AAGACACACC CCCAATAGTG 
TCACAATTTC CCGGGACCAT GGCTAAACCT CCTGGATCAT TAGCCAGAAG CAGCAGCCTG 
TGCCGTTCAC GCCGCAGCAT TGTGCCGTCC TCGCCTCAGC CTCAGCGAGC TCAGCTTGCT 
CCACACGCCC CCCACCCGTC ACACCCTCGG CACCCTCACC ACCCGCAACA CACACCACAC 
TCCTTGCCTT CCCCTGATCC AGATATCCTC TCAGTGTCAA GTTGCCCTGC GCTTTATCGA 
AATGAAGAGG AGGAAGAGGC CATTTACTTC TCTGCTGAAA AGCAATGGGA AGTGCCAGAC 
ACAGCTTCAG AATGTGACTC CTTAAATTCT TCCATTGGAA GGAAACAGTC TCCTCCTTTA 
AGCCTCGAGA TATACCAAAC ATTATCTCCG CGAAAGATAT CAAGAGATGA GGTGTCCCTA 
GAGGATTCCT CCCGAGGGGA TTCGCCTGTA ACTGTGGATG TGTCTTGGGG TTCTCCCGAC 
TGTGTAGGTC TGACAGAAAC TAAGAGTATG ATCTTCAGTC CTGCAAGCAA AGTGTACAAT 
GGCATTTTGG AGAAATCCTG TAGCATGAAC CAGCTTTCCA GTGGCATCCC GGTGCCTAAA 
CCTCGCCACA CATCATGTTC CTCAGCTGGC AACGACAGTA AACCAGTTCA GGAAGCCCCA 
AGTGTTGCCA GAATAAGCAG CATCCCACAT GACCTTTGTC ATAATGGAGA GAAAAGCAAA 
AAGCCATCAA AAATCAAAAG CCTTTTTAAG AAGAAATCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001162589.1
CDS	379..2643
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEVAASYLIQAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSPPLSLEIYQTLSPRKISRDEVSLEDSSRGDSPVTVDVSWGSPDCVGLTETKSMIFSPASKVYNGILEKSCSMNQLSSGIPVPKPRHTSCSSAGNDSKPVQEAPSVARISSIPHDLCHNGEKSKKPSKIKSLFKKKSK

Target ORF information:

RefSeq Version	NM_001169118.2
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001169118.2

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG TTGCTGCTTC ATATCTGATT CAGGCAGAAA AAATTAAAAA GAAGAGAAGC 
ACAGTCTTTG GGACTCTGCA CGTTGCACAC AGCTCCTCCC TAGATGAGGT AGACCACAAA 
ATTCTGGAAG CAAAGAAAGC TCTCTCTGAG TTGACAACTT GTTTACGAGA ACGACTTTTT 
CGCTGGCAAC AAATTGAGAA GATCTGTGGC TTTCAGATAG CCCATAACTC AGGACTCCCC 
AGCCTGACCT CTTCCCTTTA TTCTGATCAC AGCTGGGTGG TGATGCCCAG AGTCTCCATT 
CCACCCTATC CAATTGCTGG AGGAGTTGAT GACTTAGATG AAGACACACC CCCAATAGTG 
TCACAATTTC CCGGGACCAT GGCTAAACCT CCTGGATCAT TAGCCAGAAG CAGCAGCCTG 
TGCCGTTCAC GCCGCAGCAT TGTGCCGTCC TCGCCTCAGC CTCAGCGAGC TCAGCTTGCT 
CCACACGCCC CCCACCCGTC ACACCCTCGG CACCCTCACC ACCCGCAACA CACACCACAC 
TCCTTGCCTT CCCCTGATCC AGATATCCTC TCAGTGTCAA GTTGCCCTGC GCTTTATCGA 
AATGAAGAGG AGGAAGAGGC CATTTACTTC TCTGCTGAAA AGCAATGGGA AGTGCCAGAC 
ACAGCTTCAG AATGTGACTC CTTAAATTCT TCCATTGGAA GGAAACAGTC TCCTCCTTTA 
AGCCTCGAGA TATACCAAAC ATTATCTCCG CGAAAGATAT CAAGAGATGA GGTGTCCCTA 
GAGGATTCCT CCCGAGGGGA TTCGCCTGTA ACTGTGGATG TGTCTTGGGG TTCTCCCGAC 
TGTGTAGGTC TGACAGAAAC TAAGAGTATG ATCTTCAGTC CTGCAAGCAA AGTGTACAAT 
GGCATTTTGG AGAAATCCTG TAGCATGAAC CAGCTTTCCA GTGGCATCCC GGTGCCTAAA 
CCTCGCCACA CATCATGTTC CTCAGCTGGC AACGACAGTA AACCAGTTCA GGAAGCCCCA 
AGTGTTGCCA GAATAAGCAG CATCCCACAT GACCTTTGTC ATAATGGAGA GAAAAGCAAA 
AAGCCATCAA AAATCAAAAG CCTTTTTAAG AAGAAATCTA AGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

STIM2 ( NM_020860.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_065911.3 Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.

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CloneID	OHu108566
Clone ID Related Accession (Same CDS sequence)	NM_020860.4
Accession Version	NM_020860.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2241bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-26
Organism	Homo sapiens(human)
Product	stromal interaction molecule 2 isoform 2 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AC106047.5 and AC006928.15. On Jun 2, 2019 this sequence version replaced NM_020860.3. Transcript Variant: This variant (2, also known as STIM2.2 or STIM2alpha) lacks an alternate in-frame exon in the central coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. This isoform functions as a positive regulator of store-operated calcium entry (SOCE). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB040915.1, SRR1803617.151765.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: experimental evidence (PMID:11463338) non-AUG initiation codon :: PMID: 11463338 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGGGAAGTG CCAGACACAG CTTCAGAATG TGACTCCTTA 
AATTCTTCCA TTGGAAGGAA ACAGTCTCCT CCTTTAAGCC TCGAGATATA CCAAACATTA 
TCTCCGCGAA AGATATCAAG AGATGAGGTG TCCCTAGAGG ATTCCTCCCG AGGGGATTCG 
CCTGTAACTG TGGATGTGTC TTGGGGTTCT CCCGACTGTG TAGGTCTGAC AGAAACTAAG 
AGTATGATCT TCAGTCCTGC AAGCAAAGTG TACAATGGCA TTTTGGAGAA ATCCTGTAGC 
ATGAACCAGC TTTCCAGTGG CATCCCGGTG CCTAAACCTC GCCACACATC ATGTTCCTCA 
GCTGGCAACG ACAGTAAACC AGTTCAGGAA GCCCCAAGTG TTGCCAGAAT AAGCAGCATC 
CCACATGACC TTTGTCATAA TGGAGAGAAA AGCAAAAAGC CATCAAAAAT CAAAAGCCTT 
TTTAAGAAGA AATCTAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_065911.3
CDS	379..2619
Translation	LLVLGLLVAGAADGCELVPRHLRGRRATGSAATAASSPAAAAGDSPALMTDPCMSLSPPCFTEEDRFSLEALQTIHKQMDDDKDGGIEVEESDEFIREDMKYKDATNKHSHLHREDKHITIEDLWKRWKTSEVHNWTLEDTLQWLIEFVELPQYEKNFRDNNVKGTTLPRIAVHEPSFMISQLKISDRSHRQKLQLKALDVVLFGPLTRPPHNWMKDFILTVSIVIGVGGCWFAYTQNKTSKEHVAKMMKDLESLQTAEQSLMDLQERLEKAQEENRNVAVEKQNLERKMMDEINYAKEEACRLRELREGAECELSRRQYAEQELEQVRMALKKAEKEFELRSSWSVPDALQKWLQLTHEVEVQYYNIKRQNAEMQLAIAKDEAEKIKKKRSTVFGTLHVAHSSSLDEVDHKILEAKKALSELTTCLRERLFRWQQIEKICGFQIAHNSGLPSLTSSLYSDHSWVVMPRVSIPPYPIAGGVDDLDEDTPPIVSQFPGTMAKPPGSLARSSSLCRSRRSIVPSSPQPQRAQLAPHAPHPSHPRHPHHPQHTPHSLPSPDPDILSVSSCPALYRNEEEEEAIYFSAEKQWEVPDTASECDSLNSSIGRKQSPPLSLEIYQTLSPRKISRDEVSLEDSSRGDSPVTVDVSWGSPDCVGLTETKSMIFSPASKVYNGILEKSCSMNQLSSGIPVPKPRHTSCSSAGNDSKPVQEAPSVARISSIPHDLCHNGEKSKKPSKIKSLFKKKSK

Target ORF information:

RefSeq Version	NM_020860.4
Organism	Homo sapiens(human)
Definition	Homo sapiens stromal interaction molecule 2 (STIM2), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_020860.4

ORF Insert Sequence:

TTGCTGGTGC TCGGGCTGCT GGTAGCCGGA GCGGCGGACG GATGCGAGCT TGTGCCCCGG 
CACCTCCGCG GGCGGCGGGC GACTGGCTCT GCCGCAACTG CCGCCTCCTC TCCCGCCGCG 
GCGGCCGGCG ATAGCCCGGC GCTCATGACA GATCCCTGCA TGTCACTGAG TCCACCATGC 
TTTACAGAAG AAGACAGATT TAGTCTGGAA GCTCTTCAAA CAATACATAA ACAAATGGAT 
GATGACAAAG ATGGTGGAAT TGAAGTAGAG GAAAGTGATG AATTCATCAG AGAAGATATG 
AAATATAAAG ATGCTACTAA TAAACACAGC CATCTGCACA GAGAAGATAA ACATATAACG 
ATTGAGGATT TATGGAAACG ATGGAAAACA TCAGAAGTTC ATAATTGGAC CCTTGAAGAC 
ACTCTTCAGT GGTTGATAGA GTTTGTTGAA CTACCCCAAT ATGAGAAGAA TTTTAGAGAC 
AACAATGTCA AAGGAACGAC ACTTCCCAGG ATAGCAGTGC ACGAACCTTC ATTTATGATC 
TCCCAGTTGA AAATCAGTGA CCGGAGTCAC AGACAAAAAC TTCAGCTCAA GGCATTGGAT 
GTGGTTTTGT TTGGACCTCT AACACGCCCA CCTCATAACT GGATGAAAGA TTTTATCCTC 
ACAGTTTCTA TAGTAATTGG TGTTGGAGGC TGCTGGTTTG CTTATACGCA GAATAAGACA 
TCAAAAGAAC ATGTTGCAAA AATGATGAAA GATTTAGAGA GCTTACAAAC TGCAGAGCAA 
AGTCTAATGG ACTTACAGGA GAGGCTTGAA AAGGCACAGG AAGAAAACAG AAATGTTGCT 
GTAGAAAAGC AAAATTTAGA GCGCAAAATG ATGGATGAAA TCAATTATGC AAAGGAGGAG 
GCTTGTCGGC TGAGAGAGCT AAGGGAGGGA GCTGAATGTG AATTGAGTAG ACGTCAGTAT 
GCAGAACAGG AATTGGAACA GGTTCGCATG GCTCTGAAAA AGGCCGAAAA AGAATTTGAA 
CTGAGAAGCA GTTGGTCTGT TCCAGATGCA CTTCAGAAAT GGCTTCAGTT AACACATGAA 
GTAGAAGTGC AATACTACAA TATTAAAAGA CAAAACGCTG AAATGCAGCT AGCTATTGCT 
AAAGATGAGG CAGAAAAAAT TAAAAAGAAG AGAAGCACAG TCTTTGGGAC TCTGCACGTT 
GCACACAGCT CCTCCCTAGA TGAGGTAGAC CACAAAATTC TGGAAGCAAA GAAAGCTCTC 
TCTGAGTTGA CAACTTGTTT ACGAGAACGA CTTTTTCGCT GGCAACAAAT TGAGAAGATC 
TGTGGCTTTC AGATAGCCCA TAACTCAGGA CTCCCCAGCC TGACCTCTTC CCTTTATTCT 
GATCACAGCT GGGTGGTGAT GCCCAGAGTC TCCATTCCAC CCTATCCAAT TGCTGGAGGA 
GTTGATGACT TAGATGAAGA CACACCCCCA ATAGTGTCAC AATTTCCCGG GACCATGGCT 
AAACCTCCTG GATCATTAGC CAGAAGCAGC AGCCTGTGCC GTTCACGCCG CAGCATTGTG 
CCGTCCTCGC CTCAGCCTCA GCGAGCTCAG CTTGCTCCAC ACGCCCCCCA CCCGTCACAC 
CCTCGGCACC CTCACCACCC GCAACACACA CCACACTCCT TGCCTTCCCC TGATCCAGAT 
ATCCTCTCAG TGTCAAGTTG CCCTGCGCTT TATCGAAATG AAGAGGAGGA AGAGGCCATT 
TACTTCTCTG CTGAAAAGCA ATGGGAAGTG CCAGACACAG CTTCAGAATG TGACTCCTTA 
AATTCTTCCA TTGGAAGGAA ACAGTCTCCT CCTTTAAGCC TCGAGATATA CCAAACATTA 
TCTCCGCGAA AGATATCAAG AGATGAGGTG TCCCTAGAGG ATTCCTCCCG AGGGGATTCG 
CCTGTAACTG TGGATGTGTC TTGGGGTTCT CCCGACTGTG TAGGTCTGAC AGAAACTAAG 
AGTATGATCT TCAGTCCTGC AAGCAAAGTG TACAATGGCA TTTTGGAGAA ATCCTGTAGC 
ATGAACCAGC TTTCCAGTGG CATCCCGGTG CCTAAACCTC GCCACACATC ATGTTCCTCA 
GCTGGCAACG ACAGTAAACC AGTTCAGGAA GCCCCAAGTG TTGCCAGAAT AAGCAGCATC 
CCACATGACC TTTGTCATAA TGGAGAGAAA AGCAAAAAGC CATCAAAAAT CAAAAGCCTT 
TTTAAGAAGA AATCTAAGTG A

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

STIM1 and STIM2 differently regulate endogenous Ca
Biochemical and biophysical research communications488(1)74-80(2017 06)
Zhang S,Miao Y,Zheng X,Gong Y,Zhang J,Zou F,Cai C

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STIM2 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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