PTGFR cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PTGFR
Entrez Gene ID	5737
Full Name	prostaglandin F receptor
Synonyms	FP
General protein information	Preferred Names prostaglandin F receptor Names prostaglandin F2-alpha receptor FP prostanoid receptor PGF receptor PGF2 alpha receptor prostaglandin receptor (2-alpha) prostanoid FP receptor
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1p31.1
Summary	The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
Disorder MIM:	600563

mRNA and Protein(s)

mRNA	Protein	Name
XM_017001873.1	XP_016857362.1	prostaglandin F2-alpha receptor isoform X1
NM_000959.4	NP_000950.1	prostaglandin F2-alpha receptor isoform a precursor
NM_000959.3	NP_000950.1	prostaglandin F2-alpha receptor isoform a precursor
XM_006710781.2	XP_006710844.1	prostaglandin F2-alpha receptor isoform X1
NM_001039585.1	NP_001034674.1	prostaglandin F2-alpha receptor isoform b precursor
NM_001039585.2	NP_001034674.1	prostaglandin F2-alpha receptor isoform b precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PTGFR	XP_513513.2
Canis lupus familiaris (dog)	PTGFR	NP_001041562.1
Danio rerio (zebrafish)	ptgfr	NP_001172000.1
Xenopus tropicalis (tropical clawed frog)	LOC101731528	XP_004913970.1
Xenopus tropicalis (tropical clawed frog)	ptgfr	NP_001121490.1
	PTGFR	XP_001104323.1
Bos taurus (cattle)	PTGFR	NP_851368.1
Gallus gallus (chicken)	PTGFR	NP_001038122.1
Homo sapiens (human)	PTGFR	NP_000950.1
Mus musculus (house mouse)	Ptgfr	NP_032992.1
Rattus norvegicus (Norway rat)	Ptgfr	NP_037247.1
Danio rerio (zebrafish)	LOC100005681	XP_001920603.1

Gene Ontology
Bibliography

Related articles in PubMed

Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2? receptors.
Sleno R, Devost D, P?trin D, Zhang A, Bourque K, Shinjo Y, Aoki J, Inoue A, H?bert TE
The Journal of biological chemistry292(29)12139-12152(2017 07)

Correlations of AFAP1, GMDS and PTGFR gene polymorphisms with intra-ocular pressure response to latanoprost in patients with primary open-angle glaucoma.
Cui XJ, Zhao AG, Wang XL
Journal of clinical pharmacy and therapeutics42(1)87-92(2017 Feb)

11?-Prostaglandin F2?, a bioactive metabolite catalyzed by AKR1C3, stimulates prostaglandin F receptor and induces slug expression in breast cancer.
Yoda T, Kikuchi K, Miki Y, Onodera Y, Hata S, Takagi K, Nakamura Y, Hirakawa H, Ishida T, Suzuki T, Ohuchi N, Sasano H, McNamara KM
Molecular and cellular endocrinology413236-47(2015 Sep)

Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2? Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population.
Xiao B, Gu SM, Li MJ, Li J, Tao B, Wang Y, Wang Y, Zuo S, Shen Y, Yu Y, Chen D, Chen G, Kong D, Tang J, Liu Q, Chen DR, Liu Y, Alberti S, Dovizio M, Landolfi R, Mucci L, Miao PZ, Gao P, Zhu DL, Wang J, Li B, Patrignani P, Yu Y
Arteriosclerosis, thrombosis, and vascular biology35(7)1687-95(2015 Jul)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that allosteric communication between heterodimeric AT1R and PTGFR is mediated through GNAQ and may also involve proximal phospholipase C but not distal protein kinase C signaling partners; PTGFR activation has negligible effects on AT1R-based conformational biosensors. (AT1R = angiotensin II receptor, type 1; PTGFR = prostaglandin F2alpha receptor; GNAQ = GTP-binding protein G[q] subunit alpha)
Title: Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2? receptors.

The genotype frequencies of six SNPs in AFAP1, GMDS and PTGFR genes were conformed to Hardy-Weinberg equilibrium (HWE).
Title: Correlations of AFAP1, GMDS and PTGFR gene polymorphisms with intra-ocular pressure response to latanoprost in patients with primary open-angle glaucoma.

these results indicated that the actions of AKR1C3 can produce FP receptor ligands whose activation results in carcinoma cell survival in breast cancer.
Title: 11?-Prostaglandin F2?, a bioactive metabolite catalyzed by AKR1C3, stimulates prostaglandin F receptor and induces slug expression in breast cancer.

The results indicated that the rs12731181 G allele of the Prostaglandin F2alpha Receptor Gene was associated with susceptibility to essential hypertension.
Title: Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2? Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population.

The SNPs of the PTGFR and MMP-1 genes may determine the latanoprost response in a white European Spanish population.
Title: Association between SNPs of Metalloproteinases and Prostaglandin F2? Receptor Genes and Latanoprost Response in Open-Angle Glaucoma.

The following PTGFR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PTGFR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu30251	NM_001039585.2 Latest version!	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu30481	NM_000959.4 Latest version!	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu30481	XM_006710781.2 Latest version!	Homo sapiens prostaglandin F receptor (FP) (PTGFR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu90297	XM_017001873.1 Latest version!	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu30481	NM_000959.3	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$159.50-$223.30 $319.00
OHu30251	NM_001039585.1	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PTGFR ( NM_001039585.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034674.1 Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30251
Clone ID Related Accession (Same CDS sequence)	NM_001039585.1 , NM_001039585.2
Accession Version	NM_001039585.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-15
Organism	Homo sapiens(human)
Product	prostaglandin F2-alpha receptor isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL136324.6, BC112965.2 and CD013876.1. Transcript Variant: This variant (2) contains an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY485530.1, CD013876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGG TTACAATGGC CAACATTGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034674.1
CDS	267..1160
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRLQWPTLE

Target ORF information:

RefSeq Version	NM_001039585.1
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039585.1

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGG TTACAATGGC CAACATTGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGFR ( NM_001039585.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001034674.1 Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu30251
Clone ID Related Accession (Same CDS sequence)	NM_001039585.1 , NM_001039585.2
Accession Version	NM_001039585.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 894bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-27
Organism	Homo sapiens(human)
Product	prostaglandin F2-alpha receptor isoform b precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL136324.6, BC112965.2 and CD013876.1. On May 31, 2019 this sequence version replaced NM_001039585.1. Transcript Variant: This variant (2) contains an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (b) is shorter and has a distinct C-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY485530.1, CD013876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGG TTACAATGGC CAACATTGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001034674.1
CDS	336..1229
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRLQWPTLE

Target ORF information:

RefSeq Version	NM_001039585.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001039585.2

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGG TTACAATGGC CAACATTGGA ATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGFR ( NM_000959.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000950.1 Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu30481
Clone ID Related Accession (Same CDS sequence)	NM_000959.4 , NM_000959.3 , XM_006710781.2
Accession Version	NM_000959.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-30
Organism	Homo sapiens(human)
Product	prostaglandin F2-alpha receptor isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL136324.6 and BC112965.2. This sequence is a reference standard in the RefSeqGene project. On Nov 23, 2018 this sequence version replaced NM_000959.3. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.38271.1, SRR1803614.169721.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370757.8/ ENSP00000359793.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000950.1
CDS	336..1415
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST

Target ORF information:

RefSeq Version	NM_000959.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000959.4

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGFR ( NM_000959.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000950.1 Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.

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CloneID	OHu30481
Clone ID Related Accession (Same CDS sequence)	NM_000959.4 , NM_000959.3 , XM_006710781.2
Accession Version	NM_000959.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-26
Organism	Homo sapiens(human)
Product	prostaglandin F2-alpha receptor isoform a precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL136324.6 and BC112965.2. This sequence is a reference standard in the RefSeqGene project. On Feb 23, 2006 this sequence version replaced NM_000959.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.38271.1, SRR1803614.169721.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: full length.

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000950.1
CDS	267..1346
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST

Target ORF information:

RefSeq Version	NM_000959.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000959.3

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGFR ( XM_006710781.2 ) cDNA ORF clone, Homo sapiens(human) -> XP_006710844.1 Homo sapiens prostaglandin F receptor (FP) (PTGFR), transcript variant X1, mRNA.

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CloneID	OHu30481
Clone ID Related Accession (Same CDS sequence)	NM_000959.4 , NM_000959.3 , XM_006710781.2
Accession Version	XM_006710781.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1080bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	prostaglandin F2-alpha receptor isoform X1
Comment

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_006710844.1
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLVTMANIGINGNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLKNLYKLASQCCGVHVISLHIWELSSIKNSLKVAAISESPVAEKSAST

Target ORF information:

RefSeq Version	XM_006710781.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens prostaglandin F receptor (FP) (PTGFR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_006710781.2

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGT TACAATGGCC AACATTGGAA TAAATGGAAA TCATTCTCTG 
GAAACCTGTG AAACAACACT TTTTGCTCTC CGAATGGCAA CATGGAATCA AATCTTAGAT 
CCTTGGGTAT ATATTCTTCT ACGAAAGGCT GTCCTTAAGA ATCTCTATAA GCTTGCCAGT 
CAATGCTGTG GAGTGCATGT CATCAGCTTA CATATTTGGG AGCTTAGTTC CATTAAAAAT 
TCCTTAAAGG TTGCTGCTAT TTCTGAGTCA CCAGTTGCAG AGAAATCAGC AAGCACCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PTGFR ( XM_017001873.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_016857362.1 Homo sapiens prostaglandin F receptor (PTGFR), transcript variant X1, mRNA.

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CloneID	OHu90297
Clone ID Related Accession (Same CDS sequence)	XM_017001873.1
Accession Version	XM_017001873.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 876bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	prostaglandin F2-alpha receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGA AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016857362.1
CDS	336..1211
Translation	MSMNNSKQLVSPAAALLSNTTCQTENRLSVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHLINGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIFHSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYLLLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQGRSHHLEMVIQLLAIMCVSCICWSPFLGYRIILNGKEKYKVYEEQSDFLHRK

Target ORF information:

RefSeq Version	XM_017001873.1
Organism	Homo sapiens(human)
Definition	Homo sapiens prostaglandin F receptor (PTGFR), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017001873.1

ORF Insert Sequence:

ATGTCCATGA ACAATTCCAA ACAGCTAGTG TCTCCTGCAG CTGCGCTTCT TTCAAACACA 
ACCTGCCAGA CGGAAAACCG GCTTTCCGTA TTTTTTTCAG TAATCTTCAT GACAGTGGGA 
ATCTTGTCAA ACAGCCTTGC CATCGCCATT CTCATGAAGG CATATCAGAG ATTTAGACAG 
AAGTCCAAGG CATCGTTTCT GCTTTTGGCC AGTGGCCTGG TAATCACTGA TTTCTTTGGC 
CATCTCATCA ATGGAGCCAT AGCAGTATTT GTATATGCTT CTGATAAAGA ATGGATCCGC 
TTTGACCAAT CAAATGTCCT TTGCAGTATT TTTGGTATCT GCATGGTGTT TTCTGGTCTG 
TGCCCACTTC TTCTAGGCAG TGTGATGGCC ATTGAGCGGT GTATTGGAGT CACAAAACCA 
ATATTTCATT CTACGAAAAT TACATCCAAA CATGTGAAAA TGATGTTAAG TGGTGTGTGC 
TTGTTTGCTG TTTTCATAGC TTTGCTGCCC ATCCTTGGAC ATCGAGACTA TAAAATTCAG 
GCGTCGAGGA CCTGGTGTTT CTACAACACA GAAGACATCA AAGACTGGGA AGATAGATTT 
TATCTTCTAC TTTTTTCTTT TCTGGGGCTC TTAGCCCTTG GTGTTTCATT GTTGTGCAAT 
GCAATCACAG GAATTACACT TTTAAGAGTT AAATTTAAAA GTCAGCAGCA CAGACAAGGC 
AGATCTCATC ATTTGGAAAT GGTAATCCAG CTCCTGGCGA TAATGTGTGT CTCCTGTATT 
TGTTGGAGCC CATTTCTGGG ATACAGAATA ATTTTGAATG GGAAAGAGAA ATATAAAGTA 
TATGAAGAGC AAAGTGATTT CTTACATAGA AAATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conformational biosensors reveal allosteric interactions between heterodimeric AT1 angiotensin and prostaglandin F2? receptors.
The Journal of biological chemistry292(29)12139-12152(2017 07)
Sleno R,Devost D,P?trin D,Zhang A,Bourque K,Shinjo Y,Aoki J,Inoue A,H?bert TE

Correlations of AFAP1, GMDS and PTGFR gene polymorphisms with intra-ocular pressure response to latanoprost in patients with primary open-angle glaucoma.
Journal of clinical pharmacy and therapeutics42(1)87-92(2017 Feb)
Cui XJ,Zhao AG,Wang XL

11?-Prostaglandin F2?, a bioactive metabolite catalyzed by AKR1C3, stimulates prostaglandin F receptor and induces slug expression in breast cancer.
Molecular and cellular endocrinology413236-47(2015 Sep)
Yoda T,Kikuchi K,Miki Y,Onodera Y,Hata S,Takagi K,Nakamura Y,Hirakawa H,Ishida T,Suzuki T,Ohuchi N,Sasano H,McNamara KM

Rare SNP rs12731181 in the miR-590-3p Target Site of the Prostaglandin F2? Receptor Gene Confers Risk for Essential Hypertension in the Han Chinese Population.
Arteriosclerosis, thrombosis, and vascular biology35(7)1687-95(2015 Jul)
Xiao B,Gu SM,Li MJ,Li J,Tao B,Wang Y,Wang Y,Zuo S,Shen Y,Yu Y,Chen D,Chen G,Kong D,Tang J,Liu Q,Chen DR,Liu Y,Alberti S,Dovizio M,Landolfi R,Mucci L,Miao PZ,Gao P,Zhu DL,Wang J,Li B,Patrignani P,Yu Y

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PTGFR cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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