PSMB6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PSMB6
Entrez Gene ID	5694
Full Name	proteasome subunit beta 6
Synonyms	DELTA,LMPY,Y
General protein information	Preferred Names proteasome subunit beta 6 Names proteasome subunit beta type-6 PSY large multifunctional protease Y macropain delta chain multicatalytic endopeptidase complex delta chain proteasome (prosome, macropain) subunit, beta type, 6 proteasome catalytic subunit 1 proteasome delta chain proteasome subunit Y proteasome subunit delta
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 17 Map Location: 17p13.2
Summary	The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. The encoded protein is a member of the proteasome B-type family, also known as the T1B family, and is a 20S core beta subunit in the proteasome. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jul 2012].
Disorder MIM:	600307

mRNA and Protein(s)

mRNA	Protein	Name
NM_002798.2	NP_002789.1	proteasome subunit beta type-6 isoform 1 precursor
NM_002798.3	NP_002789.1	proteasome subunit beta type-6 isoform 1
NM_001270481.1	NP_001257410.1	proteasome subunit beta type-6 isoform 2

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Psmb6	NP_032972.3
Canis lupus familiaris (dog)	PSMB6	XP_849241.1
Oryza sativa (rice)	Os06g0139900	NP_001056748.1
Bos taurus (cattle)	PSMB6	NP_001029541.1
Magnaporthe oryzae (rice blast fungus)	MGG_02086	XP_003708856.1
Homo sapiens (human)	PSMB6	NP_002789.1
	PSMB6	XP_001096870.1
Eremothecium gossypii	AGOS_AAL172C	NP_982370.1
Arabidopsis thaliana (thale cress)	PBA1	NP_001031759.1
Oryza sativa (rice)	Os02g0770000	NP_001048247.1
Xenopus tropicalis (tropical clawed frog)	psmb6	NP_989151.1
Pan troglodytes (chimpanzee)	PSMB6	XP_511290.2
Danio rerio (zebrafish)	psmb6	NP_571227.1
Saccharomyces cerevisiae (baker's yeast)	PRE3	NP_012533.1
Kluyveromyces lactis	KLLA0F12936g	XP_455662.1
Schizosaccharomyces pombe (fission yeast)	pre3	NP_596295.1
Neurospora crassa	NCU09290	XP_958142.2

Gene Ontology
Bibliography

Related articles in PubMed

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Guo Z, Neilson LJ, Zhong H, Murray PS, Zanivan S, Zaidel-Bar R
Science signaling7(354)rs7(2014 Dec)

Sequence analysis of ?-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone.
Lichter DI, Danaee H, Pickard MD, Tayber O, Sintchak M, Shi H, Richardson PG, Cavenagh J, Blad? J, Fa?on T, Niesvizky R, Alsina M, Dalton W, Sonneveld P, Lonial S, van de Velde H, Ricci D, Esseltine DL, Trepicchio WL, Mulligan G, Anderson KC
Blood120(23)4513-6(2012 Nov)

Proteomic characterization of the human sperm nucleus.
de Mateo S, Castillo J, Estanyol JM, Ballesc? JL, Oliva R
Proteomics11(13)2714-26(2011 Jul)

Evaluation of Zinc-?-2-Glycoprotein and Proteasome Subunit ?-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology.
O'Hurley G, O'Grady A, Smyth P, Byrne J, O'Leary JJ, Sheils O, William R, Watson G, Kay EW
Applied immunohistochemistry & molecular morphology : AIMM18(6)512-7(2010 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate that treatment-emergent resistance to single-agent bortezomib was independent of variants in the proteasome genes PSMB1, PSMB5, PSMB6, PSMB8, PSMB9, and PSMB10.
Title: Sequence analysis of ?-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone.

results indicate ZAG as a possible predictive marker of Gleason grade. The inverse association between grade and tissue expression with a rising serum protein level is similar to that seen with prostate-specific antigen. In addition, the results for both ZAG and PSMB-6 highlight the challenges in trying to associate the protein levels in serum with tissue expression
Title: Evaluation of Zinc-?-2-Glycoprotein and Proteasome Subunit ?-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology.

The following PSMB6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PSMB6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu09574	NM_002798.3 Latest version!	Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu09774	NM_001270481.1 Latest version!	Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$139.30 $199.00
View Old Accession Versions >>
OHu09574	NM_002798.2	Homo sapiens proteasome subunit beta 6 (PSMB6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PSMB6 ( NM_002798.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_002789.1 Homo sapiens proteasome subunit beta 6 (PSMB6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09574
Clone ID Related Accession (Same CDS sequence)	NM_002798.2 , NM_002798.3
Accession Version	NM_002798.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	proteasome subunit beta type-6 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF671774.1, BC000835.2 and BM553399.1. On Jul 11, 2012 this sequence version replaced NM_002798.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.257975.1, CD051012.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTC TCGCTTTGGC CATGGAGCGG 
GATGGCTCCA GTGGAGGAGT GATCCGCCTG GCAGCCATTG CAGAGTCAGG GGTAGAGCGG 
CAAGTACTTT TGGGAGACCA GATACCCAAA TTCGCCGTTG CCACTTTACC ACCCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002789.1
CDS	52..771
Translation	MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA

Target ORF information:

RefSeq Version	NM_002798.2
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome subunit beta 6 (PSMB6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002798.2

ORF Insert Sequence:

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTC TCGCTTTGGC CATGGAGCGG 
GATGGCTCCA GTGGAGGAGT GATCCGCCTG GCAGCCATTG CAGAGTCAGG GGTAGAGCGG 
CAAGTACTTT TGGGAGACCA GATACCCAAA TTCGCCGTTG CCACTTTACC ACCCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSMB6 ( NM_002798.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_002789.1 Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09574
Clone ID Related Accession (Same CDS sequence)	NM_002798.2 , NM_002798.3
Accession Version	NM_002798.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 720bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	proteasome subunit beta type-6 isoform 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF671774.1 and BC000835.2. On Nov 23, 2018 this sequence version replaced NM_002798.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.44608.1, SRR5189661.178261.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000270586.8/ ENSP00000270586.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTC TCGCTTTGGC CATGGAGCGG 
GATGGCTCCA GTGGAGGAGT GATCCGCCTG GCAGCCATTG CAGAGTCAGG GGTAGAGCGG 
CAAGTACTTT TGGGAGACCA GATACCCAAA TTCGCCGTTG CCACTTTACC ACCCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_002789.1
CDS	32..751
Translation	MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAIAESGVERQVLLGDQIPKFAVATLPPA

Target ORF information:

RefSeq Version	NM_002798.3
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_002798.3

ORF Insert Sequence:

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTC TCGCTTTGGC CATGGAGCGG 
GATGGCTCCA GTGGAGGAGT GATCCGCCTG GCAGCCATTG CAGAGTCAGG GGTAGAGCGG 
CAAGTACTTT TGGGAGACCA GATACCCAAA TTCGCCGTTG CCACTTTACC ACCCGCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PSMB6 ( NM_001270481.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001257410.1 Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu09774
Clone ID Related Accession (Same CDS sequence)	NM_001270481.1
Accession Version	NM_001270481.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 642bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-27
Organism	Homo sapiens(human)
Product	proteasome subunit beta type-6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF671774.1, BU848746.1 and BM553399.1. Transcript Variant: This variant (2) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (2) is shorter and has a distinct C-terminus, compared to isoform 1. It is not known whether this isoform (2) is proteolytically processed in the same manner as isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BU848746.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2148093, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTT TCTTCTTTTA TCCACAGCTC 
TCGCTTTGGC CATGGAGCGG GATGGCTCCA GTGGAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001257410.1
CDS	52..693
Translation	MAATLLAARGAGPAPAWGPEAFTPDWESREVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYREDLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANAFFFYPQLSLWPWSGMAPVEE

Target ORF information:

RefSeq Version	NM_001270481.1
Organism	Homo sapiens(human)
Definition	Homo sapiens proteasome 20S subunit beta 6 (PSMB6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001270481.1

ORF Insert Sequence:

ATGGCGGCTA CCTTACTAGC TGCTCGGGGA GCCGGGCCAG CACCGGCTTG GGGGCCGGAG 
GCGTTCACTC CAGACTGGGA AAGCCGAGAA GTTTCCACTG GGACCACTAT CATGGCCGTG 
CAGTTTGACG GGGGCGTGGT TCTGGGGGCG GACTCCAGAA CAACCACTGG GTCCTACATC 
GCCAATCGAG TGACTGACAA GCTGACACCT ATTCACGACC GCATTTTCTG CTGTCGCTCA 
GGCTCAGCTG CTGATACCCA GGCAGTAGCT GATGCTGTCA CCTACCAGCT CGGTTTCCAC 
AGCATTGAAC TGAATGAGCC TCCACTGGTC CACACAGCAG CCAGCCTCTT TAAGGAGATG 
TGTTACCGAT ACCGGGAAGA CCTGATGGCG GGAATCATCA TCGCAGGCTG GGACCCTCAA 
GAAGGAGGGC AGGTGTACTC AGTGCCTATG GGGGGTATGA TGGTAAGGCA GTCCTTTGCC 
ATTGGAGGCT CCGGGAGCTC CTACATCTAT GGCTATGTTG ATGCTACCTA CCGGGAAGGC 
ATGACCAAGG AAGAGTGTCT GCAATTCACT GCCAATGCTT TCTTCTTTTA TCCACAGCTC 
TCGCTTTGGC CATGGAGCGG GATGGCTCCA GTGGAGGAGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.
Science signaling7(354)rs7(2014 Dec)
Guo Z,Neilson LJ,Zhong H,Murray PS,Zanivan S,Zaidel-Bar R

Sequence analysis of ?-subunit genes of the 20S proteasome in patients with relapsed multiple myeloma treated with bortezomib or dexamethasone.
Blood120(23)4513-6(2012 Nov)
Lichter DI,Danaee H,Pickard MD,Tayber O,Sintchak M,Shi H,Richardson PG,Cavenagh J,Blad? J,Fa?on T,Niesvizky R,Alsina M,Dalton W,Sonneveld P,Lonial S,van de Velde H,Ricci D,Esseltine DL,Trepicchio WL,Mulligan G,Anderson KC

Proteomic characterization of the human sperm nucleus.
Proteomics11(13)2714-26(2011 Jul)
de Mateo S,Castillo J,Estanyol JM,Ballesc? JL,Oliva R

Evaluation of Zinc-?-2-Glycoprotein and Proteasome Subunit ?-Type 6 Expression in Prostate Cancer Using Tissue Microarray Technology.
Applied immunohistochemistry & molecular morphology : AIMM18(6)512-7(2010 Dec)
O'Hurley G,O'Grady A,Smyth P,Byrne J,O'Leary JJ,Sheils O,William R,Watson G,Kay EW

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PSMB6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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