PRNP gene cDNA ORF clone, Homo sapiens(human)

mRNA	Protein	Name
NM_183079.4	NP_898902.1	major prion protein preproprotein Prp precursor
NM_000311.5	NP_000302.1	major prion protein preproprotein Prp precursor
NM_001080121.3	NP_001073590.1	major prion protein preproprotein Prp precursor
NM_001080123.3	NP_001073592.1	major prion protein preproprotein Prp precursor
NM_001080123.1	NP_001073592.1	major prion protein preproprotein
NM_183079.3	NP_898902.1	major prion protein preproprotein Prp precursor
NM_001080121.2	NP_001073590.1	major prion protein preproprotein Prp precursor
NM_001271561.2	NP_001258490.1	alternative prion protein isoform AltPrp
NM_001080122.3	NP_001073591.1	major prion protein preproprotein Prp precursor
NM_001271561.1	NP_001258490.1	alternative prion protein isoform AltPrp
NM_001080122.2	NP_001073591.1	major prion protein preproprotein Prp precursor
NM_183079.2	NP_898902.1	major prion protein preproprotein
NM_000311.4	NP_000302.1	major prion protein preproprotein Prp precursor
NM_001080123.2	NP_001073592.1	major prion protein preproprotein Prp precursor
NM_000311.3	NP_000302.1	major prion protein preproprotein
NM_001080121.1	NP_001073590.1	major prion protein preproprotein
NM_001080122.1	NP_001073591.1	major prion protein preproprotein
NM_001271561.3	NP_001258490.1	alternative prion protein isoform AltPrp

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu20668	NM_001271561.3 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu17293	NM_000311.5 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_183079.4 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080123.3 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080121.3 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080122.3 Latest version!	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
View Old Accession Versions >>
OHu17293	NM_001080123.1	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_183079.3	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080121.2	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu20668	NM_001271561.1	Homo sapiens prion protein (PRNP), transcript variant 6, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu17293	NM_001080122.2	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_183079.2	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_000311.4	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080123.2	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_000311.3	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080121.1	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu17293	NM_001080122.1	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$69.30 $99.00
OHu20668	NM_001271561.2	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

PRNP ( NM_001271561.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258490.1 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20668
Clone ID Related Accession (Same CDS sequence)	NM_001271561.2 , NM_001271561.1 , NM_001271561.3
Accession Version	NM_001271561.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	alternative prion protein isoform AltPrp
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BC022532.1, AY008282.1 and AI131269.1. On Feb 8, 2017 this sequence version replaced NM_001271561.1. Transcript Variant: This variant (2) encodes multiple distinct proteins due to the use of alternate translation initiation codons. The longer protein (Prp, PMID:21478263) represents the canonical protein, while a shorter protein (AltPrp, PMID:21478263) that uses a different, but overlapping reading frame has also been described. Alternative prion protein (AltPrp) has no sequence similarity to Prp and localizes to the outer mitochondrial membrane. This RefSeq represents the shorter protein, AltPrp. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279861.338.1, SRR1660803.230172.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258490.1
CDS	515..736
Translation	MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE

Target ORF information:

RefSeq Version	NM_001271561.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271561.2

ORF Insert Sequence:

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001271561.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258490.1 Homo sapiens prion protein (PRNP), transcript variant 6, mRNA.

Price & Availability↑

CloneID	OHu20668
Clone ID Related Accession (Same CDS sequence)	NM_001271561.2 , NM_001271561.1 , NM_001271561.3
Accession Version	NM_001271561.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	alternative prion protein isoform AltPrp
Comment

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258490.1
Translation	MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE

Target ORF information:

RefSeq Version	NM_001271561.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 6, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271561.1

ORF Insert Sequence:

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001271561.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001258490.1 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu20668
Clone ID Related Accession (Same CDS sequence)	NM_001271561.2 , NM_001271561.1 , NM_001271561.3
Accession Version	NM_001271561.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 222bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	alternative prion protein isoform AltPrp
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BC022532.1, AY008282.1 and AI131269.1. On Jun 2, 2019 this sequence version replaced NM_001271561.2. Transcript Variant: This variant (2) encodes multiple distinct proteins due to the use of alternate translation initiation codons. The longer protein (Prp, PMID:21478263) represents the canonical protein, while a shorter protein (AltPrp, PMID:21478263) that uses a different, but overlapping reading frame has also been described. Alternative prion protein (AltPrp) has no sequence similarity to Prp and localizes to the outer mitochondrial membrane. This RefSeq represents the shorter protein, AltPrp. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022532.1, SRR1660803.143691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END##

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001258490.1
CDS	153..374
Translation	MEHWGQPIPGAGQPWRQPLPTSGRWWLGAASWWWLGAASWWWLGAAPWWWLGTASWWWLGSRRWHPQSVEQAE

Target ORF information:

RefSeq Version	NM_001271561.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001271561.3

ORF Insert Sequence:

ATGGAACACT GGGGGCAGCC GATACCCGGG GCAGGGCAGC CCTGGAGGCA ACCGCTACCC 
ACCTCAGGGC GGTGGTGGCT GGGGGCAGCC TCATGGTGGT GGCTGGGGGC AGCCTCATGG 
TGGTGGCTGG GGGCAGCCCC ATGGTGGTGG CTGGGGACAG CCTCATGGTG GTGGCTGGGG 
TCAAGGAGGT GGCACCCACA GTCAGTGGAA CAAGCCGAGT AA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_183079.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_898902.1 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_183079.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BC022532.1, AY008282.1 and AI131269.1. On Jun 2, 2019 this sequence version replaced NM_183079.3. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. This variant (2) encodes multiple distinct proteins due to the use of alternate translation initiation codons. The longer protein (Prp, PMID:21478263) represents the canonical protein, while a shorter protein (AltPrp, PMID:21478263) that uses a different, but overlapping reading frame has also been described. This RefSeq represents the longer protein, Prp. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC022532.1, SRR1660803.143691.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898902.1
CDS	64..825
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_183079.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183079.4

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_000311.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_000302.1 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_000311.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-01
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, M13899.1 and AI131269.1. This sequence is a reference standard in the RefSeqGene project. On May 17, 2019 this sequence version replaced NM_000311.4. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 can all encode the same isoform (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.111164.1, SRR1660809.259593.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000379440.9/ ENSP00000368752.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000302.1
CDS	68..829
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_000311.5
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000311.5

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080121.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073590.1 Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080121.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BP251427.1, M13899.1 and AI131269.1. On Jun 2, 2019 this sequence version replaced NM_001080121.2. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR7410570.660351.1, SRR1660803.29248.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073590.1
CDS	63..824
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080121.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080121.3

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080123.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073592.1 Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080123.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-04
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL133396.2, DB485147.1, DB461478.1, M13899.1 and AI131269.1. On Jun 2, 2019 this sequence version replaced NM_001080123.2. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803612.47049.1, SRR1803616.76336.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073592.1
CDS	292..1053
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080123.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080123.3

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080123.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073592.1 Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080123.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	major prion protein preproprotein
Comment

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073592.1
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080123.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080123.1

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_183079.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_898902.1 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_183079.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BC022532.1, AY008282.1 and AI131269.1. On Feb 8, 2017 this sequence version replaced NM_183079.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. This variant (2) encodes multiple distinct proteins due to the use of alternate translation initiation codons. The longer protein (Prp, PMID:21478263) represents the canonical protein, while a shorter protein (AltPrp, PMID:21478263) that uses a different, but overlapping reading frame has also been described. This RefSeq represents the longer protein, Prp. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: ERR279861.338.1, SRR1660803.230172.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898902.1
CDS	426..1187
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_183079.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183079.3

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080121.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073590.1 Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080121.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BP251427.1, M13899.1 and AI131269.1. On Feb 8, 2017 this sequence version replaced NM_001080121.1. Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.112390.1, SRR1803612.131196.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073590.1
CDS	425..1186
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080121.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080121.2

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080122.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073591.1 Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080122.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2020-01-03
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BI669189.1, M13899.1 and AI131269.1. On Jun 2, 2019 this sequence version replaced NM_001080122.2. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.145918.1, SRR1803611.132136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073591.1
CDS	59..820
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080122.3
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080122.3

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080122.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073591.1 Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080122.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, BI669189.1, M13899.1 and AI131269.1. On Feb 8, 2017 this sequence version replaced NM_001080122.1. Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.54774.1, SRR1803611.132136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073591.1
CDS	421..1182
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080122.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080122.2

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_183079.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_898902.1 Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_183079.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	major prion protein preproprotein
Comment

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_898902.1
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_183079.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_183079.2

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_000311.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_000302.1 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_000311.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC325819.1, M13899.1 and AI131269.1. This sequence is a reference standard in the RefSeqGene project. On Feb 8, 2017 this sequence version replaced NM_000311.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 can all encode the same isoform (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.87759.1, SRR1660807.25486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000302.1
CDS	430..1191
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_000311.4
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000311.4

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080123.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073592.1 Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080123.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-03-11
Organism	Homo sapiens(human)
Product	major prion protein preproprotein Prp precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB485147.1, DB461478.1, M13899.1 and AI131269.1. On Feb 8, 2017 this sequence version replaced NM_001080123.1. Transcript Variant: This variant (5) differs in the 5' UTR compared to variant 1. Variants 1-5 can all encode the same protein (Prp). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.49403.1, SRR1803612.47049.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073592.1
CDS	242..1003
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080123.2
Organism	Homo sapiens(human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 5, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080123.2

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_000311.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_000302.1 Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_000311.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	major prion protein preproprotein
Comment

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_000302.1
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_000311.3
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_000311.3

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080121.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073590.1 Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080121.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	major prion protein preproprotein
Comment

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073590.1
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080121.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080121.1

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PRNP ( NM_001080122.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001073591.1 Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Price & Availability↑

CloneID	OHu17293
Clone ID Related Accession (Same CDS sequence)	NM_183079.4 , NM_000311.5 , NM_001080121.3 , NM_001080123.3 , NM_001080123.1 , NM_183079.3 , NM_001080121.2 , NM_001080122.3 , NM_001080122.2 , NM_183079.2 , NM_000311.4 , NM_001080123.2 , NM_000311.3 , NM_001080121.1 , NM_001080122.1
Accession Version	NM_001080122.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 762bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-14
Organism	Homo sapiens(Human)
Product	major prion protein preproprotein
Comment

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001073591.1
Translation	MANLGCWMLVLFVATWSDLGLCKKRPKPGGWNTGGSRYPGQGSPGGNRYPPQGGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQPHGGGWGQGGGTHSQWNKPSKPKTNMKHMAGAAAAGAVVGGLGGYMLGSAMSRPIIHFGSDYEDRYYRENMHRYPNQVYYRPMDEYSNQNNFVHDCVNITIKQHTVTTTTKGENFTETDVKMMERVVEQMCITQYERESQAYYQRGSSMVLFSSPPVILLISFLIFLIVG

Target ORF information:

RefSeq Version	NM_001080122.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens prion protein (PRNP), transcript variant 4, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001080122.1

ORF Insert Sequence:

ATGGCGAACC TTGGCTGCTG GATGCTGGTT CTCTTTGTGG CCACATGGAG TGACCTGGGC 
CTCTGCAAGA AGCGCCCGAA GCCTGGAGGA TGGAACACTG GGGGCAGCCG ATACCCGGGG 
CAGGGCAGCC CTGGAGGCAA CCGCTACCCA CCTCAGGGCG GTGGTGGCTG GGGGCAGCCT 
CATGGTGGTG GCTGGGGGCA GCCTCATGGT GGTGGCTGGG GGCAGCCCCA TGGTGGTGGC 
TGGGGACAGC CTCATGGTGG TGGCTGGGGT CAAGGAGGTG GCACCCACAG TCAGTGGAAC 
AAGCCGAGTA AGCCAAAAAC CAACATGAAG CACATGGCTG GTGCTGCAGC AGCTGGGGCA 
GTGGTGGGGG GCCTTGGCGG CTACATGCTG GGAAGTGCCA TGAGCAGGCC CATCATACAT 
TTCGGCAGTG ACTATGAGGA CCGTTACTAT CGTGAAAACA TGCACCGTTA CCCCAACCAA 
GTGTACTACA GGCCCATGGA TGAGTACAGC AACCAGAACA ACTTTGTGCA CGACTGCGTC 
AATATCACAA TCAAGCAGCA CACGGTCACC ACAACCACCA AGGGGGAGAA CTTCACCGAG 
ACCGACGTTA AGATGATGGA GCGCGTGGTT GAGCAGATGT GTATCACCCA GTACGAGAGG 
GAATCTCAGG CCTATTACCA GAGAGGATCG AGCATGGTCC TCTTCTCCTC TCCACCTGTG 
ATCCTCCTGA TCTCTTTCCT CATCTTCCTG ATAGTGGGAT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Gene Symbol	PRNP
Entrez Gene ID	5621
Full Name	prion protein
Synonyms	ASCR,AltPrP,CD230,CJD,GSS,KURU,PRIP,PrP,PrP27-30,PrP33-35C,PrPc,p27-30
General protein information	Preferred Names prion protein Names major prion protein alternative prion protein CD230 antigen prion-related protein
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20p13
Summary	The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014].
Disorder MIM:	176640
Disorder Html:	Creutzfeldt-Jakob disease, 123400 (3); Gerstmann-Straussler disease, 137440 (3); Insomnia, fatal familial, 600072 (3); Prion disease with protracted course, 606688 (3); Huntington disease-like 1, 603218 (3); {Kuru, susceptibility to}, 245300 (3); Cerebral amyloid angiopathy, PRNP-related, 137440 (3)

	PRNP	NP_001040617.1
Bos taurus (cattle)	PRNP	NP_851358.2
Mus musculus (house mouse)	Prnp	NP_001265185.1
Pan troglodytes (chimpanzee)	PRNP	NP_001009093.1
Rattus norvegicus (Norway rat)	Prnp	NP_036763.1
Homo sapiens (human)	PRNP	NP_898902.1

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

PRNP cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Target ORF information:

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ORF Insert Sequence:

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Target ORF information:

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Target ORF information:

Target ORF information:

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Target ORF information:

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Target ORF information:

Target ORF information:

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Target ORF information:

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Target ORF information:

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Target ORF information:

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Target ORF information:

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Target ORF information:

Target ORF information:

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