Gene Symbol | PRLR |
Entrez Gene ID | 5618 |
Full Name | prolactin receptor |
Synonyms | HPRL,MFAB,hPRLrI |
General protein information |
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Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Summary | This gene encodes a receptor for the anterior pituitary hormone, prolactin, and belongs to the type I cytokine receptor family. Prolactin-dependent signaling occurs as the result of ligand-induced dimerization of the prolactin receptor. Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene, which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer. [provided by RefSeq, Feb 2011]. |
Disorder MIM: | |
Disorder Html: | Multiple fibroadenomas of the breast, 615554 (3); ?Hyperprolactinemia, 615555 (3) |