PCDHB6 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PCDHB6
Entrez Gene ID	56130
Full Name	protocadherin beta 6
Synonyms	PCDH-BETA6
General protein information	Preferred Names protocadherin beta 6 Names protocadherin beta-6
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 5 Map Location: 5q31.3
Summary	This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. Unlike the alpha and gamma clusters, the transcripts from these genes do not share common 3' exons. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell neural connections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014].
Disorder MIM:	606332

mRNA and Protein(s)

mRNA	Protein	Name
NM_018939.3	NP_061762.2	protocadherin beta-6 isoform 1 precursor
NM_001303145.1	NP_001290074.1	protocadherin beta-6 isoform 2
NM_001303145.2	NP_001290074.1	protocadherin beta-6 isoform 2

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	PCDHB6	NP_001013027.1
	PCDHB6	XP_001090348.1
Mus musculus (house mouse)	Pcdhb13	NP_444368.1
Homo sapiens (human)	PCDHB6	NP_061762.1
Canis lupus familiaris (dog)	PCDHB6	XP_544301.3

Gene Ontology
Bibliography

Related articles in PubMed

Protocadherins.
Frank M, Kemler R
Current opinion in cell biology14(5)557-62(2002 Oct)

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.
Vanhalst K, Kools P, Vanden Eynde E, van Roy F
FEBS letters495(1-2)120-5(2001 Apr)

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M, Noonan JP, Zhang MQ, Myers RM, Maniatis T
Genome research11(3)389-404(2001 Mar)

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Nollet F, Kools P, van Roy F
Journal of molecular biology299(3)551-72(2000 Jun)

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.
Yagi T, Takeichi M
Genes & development14(10)1169-80(2000 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PCDHB6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PCDHB6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu69940	NM_018939.3 Latest version!	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$279.50-$391.30 $559.00
OHu69941	NM_001303145.2 Latest version!	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
View Old Accession Versions >>
OHu69941	NM_001303145.1	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$307.30 $439.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PCDHB6 ( NM_018939.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_061762.2 Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 1, mRNA.

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CloneID	OHu69940
Clone ID Related Accession (Same CDS sequence)	NM_018939.3
Accession Version	NM_018939.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-21
Organism	Homo sapiens(human)
Product	protocadherin beta-6 isoform 1 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA789782.1, AF217752.1 and DA386733.1. On Dec 19, 2014 this sequence version replaced NM_018939.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, longest protein ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGATGCAAA CTAAAGTACA GAACAAGAAA AGGCAAGTGG CTTTCTTCAT TTTATTGATG 
CTTTGGGGAG AGGTGGGTTC TGAATCGATT CAGTATTCCG TATTGGAGGA GACAGAAAGT 
GGCACGTTTG TGGCCAACTT GACAAAGGAC CTGGGACTGA GGGTGGGGGA GCTGGCTTCG 
CGGGGCGCTC GGGTTGTTTT CAAAGGGAAC AGACAACATT TGCAGTTTGA TCCACAGACC 
CATGATTTAC TGCTAAATGA AAAACTGGAC CGGGAGGAGC TGTGTGGCTC CACTGAGCCG 
TGTGTGCTAC CTTTCCAAGT GTTACTGGAA AACCCCTTGC AGTTTTTTCA GGCTTCCTTG 
CGAGTCAGAG ATATAAATGA CCACGCCCCG GAATTCCCTG CCAGAGAAAT GCTCCTGAAA 
ATATCAGAAA TTACTATGCC AGGAAAGATA TTTCCTTTGA AAATGGCACA CGATTTAGAC 
ACCGGCAGCA ACGGCCTTCA GAGGTACACA ATCAGCTCCA ACCCTCACTT CCACGTTCTC 
ACCCGCAATC GCAGCGAAGG CAGGAAGTTC CCGGAGCTGG TGCTAGACAA ACCGTTGGAC 
CGCGAGGAGC AGCCCCAACT CAGGCTAACG CTGATCGCGC TGGATGGCGG GTCTCCGCCC 
CGGTCAGGGA CCTCCGAGAT TCAGATCCAG GTTTTGGACA TCAATGACAA CGTCCCCGAG 
TTTGCTCAGG AGCTCTATGA AGCACAAGTC CCTGAGAACA ACCCCCTCGG CTCTCTGGTT 
ATTACCGTCT CAGCCAGAGA TTTAGATGCA GGATCGTTTG GGAAGGTATC TTACGCCCTG 
TTTCAAGTCG ATGACGTCAA CCAACCCTTC GAAATAAACG CAATCACAGG AGAAATTCGG 
CTGAGAAAGG CTTTGGATTT TGAGGAAATT CAGTCTTATG ACGTGGATGT TGAGGCTACA 
GATGGTGGAG GCCTATCAGG AAAATGCTCT TTAGTCGTCA GGGTCCTGGA CGTGAATGAC 
AATGCCCCTG AACTCACCAT GTCGTTCTTC ATCAGCCTCA TCCCAGAAAA CTTACCAGAG 
ATCACAGTGG CAGTTTTCAG TGTTTCAGAT GCAGACTCTG GACATAACCA ACAGGTTATT 
TGTTCAATAG AGAACAATCT CCCCTTTCTA CTAAGACCTT CCGTGGAGAA TTTCTACACC 
CTGGTAACAG AAGGCGCGCT GGACAGAGAG AGCAGAGCCG AGTACAACAT CACTATCACG 
GTCACTGATT TGGGGACACC AAGGCTGAAA ACCCAGCAGA GCATAACTGT GCAGGTCTCC 
GACGTCAATG ACAACGCCCC CGCCTTCACC CAAACCTCCT ACACCCTGTT CGTCCGCGAG 
AACAACAGCC CCGCCCTGCA CATCGGCAGC GTCAGCGCCA CAGACAGAGA CTCAGGCATC 
AACGCCCAGG TCACCTACTC GCTGCTGCCG CCCCAGGACC CGCACCTGCC CCTCTCTTCC 
CTGGTCTCCA TCAACGCGGA CAACGGCCAC CTGTTTGCCC TCAGGTCGCT GGACTACGAG 
GCCCTGCAGT CTTTCGAGTT CCGCGTGGGC GCCACAGACC GCGGCTCCCC GGCGTTGAGC 
AGCGAGGCGC TGGTGCGCTT GCTGGTGCTG GACGCCAACG ACAACTCGCC CTTCGTGTTG 
TACCCGCTGC AGAACGGCTC CGCGCCCTGC ACCGAGCTGG TGCCCCGGGC GGCCGAGCCG 
GGCTACCTGG TGACCAAGGT GGTGGCGGTG GACGGCGACT CGGGCCAGAA CGCCTGGCTG 
TCGTACCAGC TGCTCAAGGC CACGGAGCTC GGTCTGTTCG GCGTGTGGGC GCACAATGGC 
GAGGTGCGCA CCGCCAGGCT GCTGAGCGAG CGAGACGCAG CCAAGCACAG GCTGGTGGTG 
CTTGTCAAGG ACAATGGCGA GCCTCCGCGC TCGGCCACCG CCACGCTGCA CGTGCTCCTG 
GTGGACGGCT TCTCCCAGCC CTACCTGCCT CTCCCTGAGG CGGCCCCGGC CCAAGCCCAG 
GCCGACTCTC TCACCGTCTA CCTGGTGGTG GCGTTGGCCT CGGTGTCGTC GCTCTTCCTC 
TTTTCGGTGC TCCTGTTCGT GGCGGTGCGG CTGTGCAGGA GGAGCAGGGC GGCCTCGGTG 
GGTCGCTACT CGGTGCCCGA GGGTCCCTTT CCAGGGCATC TGGTGGATGT GAGCGGCACC 
GGGACCCTAT CCCAGAGCTA CCAGTACAAG GTGTGTCTGA CGGGAGGCTC AGAAACAAAT 
GAGTTCAAGT TCCTGAAGCC GATTATGCCC AACTTCCCTC CTCAGGGCAC TGAGAGAGAA 
ATGGAAGAAA CCCCCACCTC TCGGAATAGC TTCCCGTTCA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_061762.2
CDS	237..2621
Translation	MMQTKVQNKKRQVAFFILLMLWGEVGSESIQYSVLEETESGTFVANLTKDLGLRVGELASRGARVVFKGNRQHLQFDPQTHDLLLNEKLDREELCGSTEPCVLPFQVLLENPLQFFQASLRVRDINDHAPEFPAREMLLKISEITMPGKIFPLKMAHDLDTGSNGLQRYTISSNPHFHVLTRNRSEGRKFPELVLDKPLDREEQPQLRLTLIALDGGSPPRSGTSEIQIQVLDINDNVPEFAQELYEAQVPENNPLGSLVITVSARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEEIQSYDVDVEATDGGGLSGKCSLVVRVLDVNDNAPELTMSFFISLIPENLPEITVAVFSVSDADSGHNQQVICSIENNLPFLLRPSVENFYTLVTEGALDRESRAEYNITITVTDLGTPRLKTQQSITVQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGINAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQSFEFRVGATDRGSPALSSEALVRLLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRYSVPEGPFPGHLVDVSGTGTLSQSYQYKVCLTGGSETNEFKFLKPIMPNFPPQGTEREMEETPTSRNSFPFS

Target ORF information:

RefSeq Version	NM_018939.3
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018939.3

ORF Insert Sequence:

ATGATGCAAA CTAAAGTACA GAACAAGAAA AGGCAAGTGG CTTTCTTCAT TTTATTGATG 
CTTTGGGGAG AGGTGGGTTC TGAATCGATT CAGTATTCCG TATTGGAGGA GACAGAAAGT 
GGCACGTTTG TGGCCAACTT GACAAAGGAC CTGGGACTGA GGGTGGGGGA GCTGGCTTCG 
CGGGGCGCTC GGGTTGTTTT CAAAGGGAAC AGACAACATT TGCAGTTTGA TCCACAGACC 
CATGATTTAC TGCTAAATGA AAAACTGGAC CGGGAGGAGC TGTGTGGCTC CACTGAGCCG 
TGTGTGCTAC CTTTCCAAGT GTTACTGGAA AACCCCTTGC AGTTTTTTCA GGCTTCCTTG 
CGAGTCAGAG ATATAAATGA CCACGCCCCG GAATTCCCTG CCAGAGAAAT GCTCCTGAAA 
ATATCAGAAA TTACTATGCC AGGAAAGATA TTTCCTTTGA AAATGGCACA CGATTTAGAC 
ACCGGCAGCA ACGGCCTTCA GAGGTACACA ATCAGCTCCA ACCCTCACTT CCACGTTCTC 
ACCCGCAATC GCAGCGAAGG CAGGAAGTTC CCGGAGCTGG TGCTAGACAA ACCGTTGGAC 
CGCGAGGAGC AGCCCCAACT CAGGCTAACG CTGATCGCGC TGGATGGCGG GTCTCCGCCC 
CGGTCAGGGA CCTCCGAGAT TCAGATCCAG GTTTTGGACA TCAATGACAA CGTCCCCGAG 
TTTGCTCAGG AGCTCTATGA AGCACAAGTC CCTGAGAACA ACCCCCTCGG CTCTCTGGTT 
ATTACCGTCT CAGCCAGAGA TTTAGATGCA GGATCGTTTG GGAAGGTATC TTACGCCCTG 
TTTCAAGTCG ATGACGTCAA CCAACCCTTC GAAATAAACG CAATCACAGG AGAAATTCGG 
CTGAGAAAGG CTTTGGATTT TGAGGAAATT CAGTCTTATG ACGTGGATGT TGAGGCTACA 
GATGGTGGAG GCCTATCAGG AAAATGCTCT TTAGTCGTCA GGGTCCTGGA CGTGAATGAC 
AATGCCCCTG AACTCACCAT GTCGTTCTTC ATCAGCCTCA TCCCAGAAAA CTTACCAGAG 
ATCACAGTGG CAGTTTTCAG TGTTTCAGAT GCAGACTCTG GACATAACCA ACAGGTTATT 
TGTTCAATAG AGAACAATCT CCCCTTTCTA CTAAGACCTT CCGTGGAGAA TTTCTACACC 
CTGGTAACAG AAGGCGCGCT GGACAGAGAG AGCAGAGCCG AGTACAACAT CACTATCACG 
GTCACTGATT TGGGGACACC AAGGCTGAAA ACCCAGCAGA GCATAACTGT GCAGGTCTCC 
GACGTCAATG ACAACGCCCC CGCCTTCACC CAAACCTCCT ACACCCTGTT CGTCCGCGAG 
AACAACAGCC CCGCCCTGCA CATCGGCAGC GTCAGCGCCA CAGACAGAGA CTCAGGCATC 
AACGCCCAGG TCACCTACTC GCTGCTGCCG CCCCAGGACC CGCACCTGCC CCTCTCTTCC 
CTGGTCTCCA TCAACGCGGA CAACGGCCAC CTGTTTGCCC TCAGGTCGCT GGACTACGAG 
GCCCTGCAGT CTTTCGAGTT CCGCGTGGGC GCCACAGACC GCGGCTCCCC GGCGTTGAGC 
AGCGAGGCGC TGGTGCGCTT GCTGGTGCTG GACGCCAACG ACAACTCGCC CTTCGTGTTG 
TACCCGCTGC AGAACGGCTC CGCGCCCTGC ACCGAGCTGG TGCCCCGGGC GGCCGAGCCG 
GGCTACCTGG TGACCAAGGT GGTGGCGGTG GACGGCGACT CGGGCCAGAA CGCCTGGCTG 
TCGTACCAGC TGCTCAAGGC CACGGAGCTC GGTCTGTTCG GCGTGTGGGC GCACAATGGC 
GAGGTGCGCA CCGCCAGGCT GCTGAGCGAG CGAGACGCAG CCAAGCACAG GCTGGTGGTG 
CTTGTCAAGG ACAATGGCGA GCCTCCGCGC TCGGCCACCG CCACGCTGCA CGTGCTCCTG 
GTGGACGGCT TCTCCCAGCC CTACCTGCCT CTCCCTGAGG CGGCCCCGGC CCAAGCCCAG 
GCCGACTCTC TCACCGTCTA CCTGGTGGTG GCGTTGGCCT CGGTGTCGTC GCTCTTCCTC 
TTTTCGGTGC TCCTGTTCGT GGCGGTGCGG CTGTGCAGGA GGAGCAGGGC GGCCTCGGTG 
GGTCGCTACT CGGTGCCCGA GGGTCCCTTT CCAGGGCATC TGGTGGATGT GAGCGGCACC 
GGGACCCTAT CCCAGAGCTA CCAGTACAAG GTGTGTCTGA CGGGAGGCTC AGAAACAAAT 
GAGTTCAAGT TCCTGAAGCC GATTATGCCC AACTTCCCTC CTCAGGGCAC TGAGAGAGAA 
ATGGAAGAAA CCCCCACCTC TCGGAATAGC TTCCCGTTCA GTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDHB6 ( NM_001303145.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290074.1 Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu69941
Clone ID Related Accession (Same CDS sequence)	NM_001303145.1 , NM_001303145.2
Accession Version	NM_001303145.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-06-29
Organism	Homo sapiens(human)
Product	protocadherin beta-6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA789782.1, AK299661.1, AF152499.1, DA386733.1 and AF217752.1. Transcript Variant: This variant (2) lacks a portion of the 5' region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK299661.1, DC375688.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCTGA AAATATCAGA AATTACTATG CCAGGAAAGA TATTTCCTTT GAAAATGGCA 
CACGATTTAG ACACCGGCAG CAACGGCCTT CAGAGGTACA CAATCAGCTC CAACCCTCAC 
TTCCACGTTC TCACCCGCAA TCGCAGCGAA GGCAGGAAGT TCCCGGAGCT GGTGCTAGAC 
AAACCGTTGG ACCGCGAGGA GCAGCCCCAA CTCAGGCTAA CGCTGATCGC GCTGGATGGC 
GGGTCTCCGC CCCGGTCAGG GACCTCCGAG ATTCAGATCC AGGTTTTGGA CATCAATGAC 
AACGTCCCCG AGTTTGCTCA GGAGCTCTAT GAAGCACAAG TCCCTGAGAA CAACCCCCTC 
GGCTCTCTGG TTATTACCGT CTCAGCCAGA GATTTAGATG CAGGATCGTT TGGGAAGGTA 
TCTTACGCCC TGTTTCAAGT CGATGACGTC AACCAACCCT TCGAAATAAA CGCAATCACA 
GGAGAAATTC GGCTGAGAAA GGCTTTGGAT TTTGAGGAAA TTCAGTCTTA TGACGTGGAT 
GTTGAGGCTA CAGATGGTGG AGGCCTATCA GGAAAATGCT CTTTAGTCGT CAGGGTCCTG 
GACGTGAATG ACAATGCCCC TGAACTCACC ATGTCGTTCT TCATCAGCCT CATCCCAGAA 
AACTTACCAG AGATCACAGT GGCAGTTTTC AGTGTTTCAG ATGCAGACTC TGGACATAAC 
CAACAGGTTA TTTGTTCAAT AGAGAACAAT CTCCCCTTTC TACTAAGACC TTCCGTGGAG 
AATTTCTACA CCCTGGTAAC AGAAGGCGCG CTGGACAGAG AGAGCAGAGC CGAGTACAAC 
ATCACTATCA CGGTCACTGA TTTGGGGACA CCAAGGCTGA AAACCCAGCA GAGCATAACT 
GTGCAGGTCT CCGACGTCAA TGACAACGCC CCCGCCTTCA CCCAAACCTC CTACACCCTG 
TTCGTCCGCG AGAACAACAG CCCCGCCCTG CACATCGGCA GCGTCAGCGC CACAGACAGA 
GACTCAGGCA TCAACGCCCA GGTCACCTAC TCGCTGCTGC CGCCCCAGGA CCCGCACCTG 
CCCCTCTCTT CCCTGGTCTC CATCAACGCG GACAACGGCC ACCTGTTTGC CCTCAGGTCG 
CTGGACTACG AGGCCCTGCA GTCTTTCGAG TTCCGCGTGG GCGCCACAGA CCGCGGCTCC 
CCGGCGTTGA GCAGCGAGGC GCTGGTGCGC TTGCTGGTGC TGGACGCCAA CGACAACTCG 
CCCTTCGTGT TGTACCCGCT GCAGAACGGC TCCGCGCCCT GCACCGAGCT GGTGCCCCGG 
GCGGCCGAGC CGGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGGCGA CTCGGGCCAG 
AACGCCTGGC TGTCGTACCA GCTGCTCAAG GCCACGGAGC TCGGTCTGTT CGGCGTGTGG 
GCGCACAATG GCGAGGTGCG CACCGCCAGG CTGCTGAGCG AGCGAGACGC AGCCAAGCAC 
AGGCTGGTGG TGCTTGTCAA GGACAATGGC GAGCCTCCGC GCTCGGCCAC CGCCACGCTG 
CACGTGCTCC TGGTGGACGG CTTCTCCCAG CCCTACCTGC CTCTCCCTGA GGCGGCCCCG 
GCCCAAGCCC AGGCCGACTC TCTCACCGTC TACCTGGTGG TGGCGTTGGC CTCGGTGTCG 
TCGCTCTTCC TCTTTTCGGT GCTCCTGTTC GTGGCGGTGC GGCTGTGCAG GAGGAGCAGG 
GCGGCCTCGG TGGGTCGCTA CTCGGTGCCC GAGGGTCCCT TTCCAGGGCA TCTGGTGGAT 
GTGAGCGGCA CCGGGACCCT ATCCCAGAGC TACCAGTACA AGGTGTGTCT GACGGGAGGC 
TCAGAAACAA ATGAGTTCAA GTTCCTGAAG CCGATTATGC CCAACTTCCC TCCTCAGGGC 
ACTGAGAGAG AAATGGAAGA AACCCCCACC TCTCGGAATA GCTTCCCGTT CAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290074.1
CDS	440..2416
Translation	MLLKISEITMPGKIFPLKMAHDLDTGSNGLQRYTISSNPHFHVLTRNRSEGRKFPELVLDKPLDREEQPQLRLTLIALDGGSPPRSGTSEIQIQVLDINDNVPEFAQELYEAQVPENNPLGSLVITVSARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEEIQSYDVDVEATDGGGLSGKCSLVVRVLDVNDNAPELTMSFFISLIPENLPEITVAVFSVSDADSGHNQQVICSIENNLPFLLRPSVENFYTLVTEGALDRESRAEYNITITVTDLGTPRLKTQQSITVQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGINAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQSFEFRVGATDRGSPALSSEALVRLLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRYSVPEGPFPGHLVDVSGTGTLSQSYQYKVCLTGGSETNEFKFLKPIMPNFPPQGTEREMEETPTSRNSFPFS

Target ORF information:

RefSeq Version	NM_001303145.1
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303145.1

ORF Insert Sequence:

ATGCTCCTGA AAATATCAGA AATTACTATG CCAGGAAAGA TATTTCCTTT GAAAATGGCA 
CACGATTTAG ACACCGGCAG CAACGGCCTT CAGAGGTACA CAATCAGCTC CAACCCTCAC 
TTCCACGTTC TCACCCGCAA TCGCAGCGAA GGCAGGAAGT TCCCGGAGCT GGTGCTAGAC 
AAACCGTTGG ACCGCGAGGA GCAGCCCCAA CTCAGGCTAA CGCTGATCGC GCTGGATGGC 
GGGTCTCCGC CCCGGTCAGG GACCTCCGAG ATTCAGATCC AGGTTTTGGA CATCAATGAC 
AACGTCCCCG AGTTTGCTCA GGAGCTCTAT GAAGCACAAG TCCCTGAGAA CAACCCCCTC 
GGCTCTCTGG TTATTACCGT CTCAGCCAGA GATTTAGATG CAGGATCGTT TGGGAAGGTA 
TCTTACGCCC TGTTTCAAGT CGATGACGTC AACCAACCCT TCGAAATAAA CGCAATCACA 
GGAGAAATTC GGCTGAGAAA GGCTTTGGAT TTTGAGGAAA TTCAGTCTTA TGACGTGGAT 
GTTGAGGCTA CAGATGGTGG AGGCCTATCA GGAAAATGCT CTTTAGTCGT CAGGGTCCTG 
GACGTGAATG ACAATGCCCC TGAACTCACC ATGTCGTTCT TCATCAGCCT CATCCCAGAA 
AACTTACCAG AGATCACAGT GGCAGTTTTC AGTGTTTCAG ATGCAGACTC TGGACATAAC 
CAACAGGTTA TTTGTTCAAT AGAGAACAAT CTCCCCTTTC TACTAAGACC TTCCGTGGAG 
AATTTCTACA CCCTGGTAAC AGAAGGCGCG CTGGACAGAG AGAGCAGAGC CGAGTACAAC 
ATCACTATCA CGGTCACTGA TTTGGGGACA CCAAGGCTGA AAACCCAGCA GAGCATAACT 
GTGCAGGTCT CCGACGTCAA TGACAACGCC CCCGCCTTCA CCCAAACCTC CTACACCCTG 
TTCGTCCGCG AGAACAACAG CCCCGCCCTG CACATCGGCA GCGTCAGCGC CACAGACAGA 
GACTCAGGCA TCAACGCCCA GGTCACCTAC TCGCTGCTGC CGCCCCAGGA CCCGCACCTG 
CCCCTCTCTT CCCTGGTCTC CATCAACGCG GACAACGGCC ACCTGTTTGC CCTCAGGTCG 
CTGGACTACG AGGCCCTGCA GTCTTTCGAG TTCCGCGTGG GCGCCACAGA CCGCGGCTCC 
CCGGCGTTGA GCAGCGAGGC GCTGGTGCGC TTGCTGGTGC TGGACGCCAA CGACAACTCG 
CCCTTCGTGT TGTACCCGCT GCAGAACGGC TCCGCGCCCT GCACCGAGCT GGTGCCCCGG 
GCGGCCGAGC CGGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGGCGA CTCGGGCCAG 
AACGCCTGGC TGTCGTACCA GCTGCTCAAG GCCACGGAGC TCGGTCTGTT CGGCGTGTGG 
GCGCACAATG GCGAGGTGCG CACCGCCAGG CTGCTGAGCG AGCGAGACGC AGCCAAGCAC 
AGGCTGGTGG TGCTTGTCAA GGACAATGGC GAGCCTCCGC GCTCGGCCAC CGCCACGCTG 
CACGTGCTCC TGGTGGACGG CTTCTCCCAG CCCTACCTGC CTCTCCCTGA GGCGGCCCCG 
GCCCAAGCCC AGGCCGACTC TCTCACCGTC TACCTGGTGG TGGCGTTGGC CTCGGTGTCG 
TCGCTCTTCC TCTTTTCGGT GCTCCTGTTC GTGGCGGTGC GGCTGTGCAG GAGGAGCAGG 
GCGGCCTCGG TGGGTCGCTA CTCGGTGCCC GAGGGTCCCT TTCCAGGGCA TCTGGTGGAT 
GTGAGCGGCA CCGGGACCCT ATCCCAGAGC TACCAGTACA AGGTGTGTCT GACGGGAGGC 
TCAGAAACAA ATGAGTTCAA GTTCCTGAAG CCGATTATGC CCAACTTCCC TCCTCAGGGC 
ACTGAGAGAG AAATGGAAGA AACCCCCACC TCTCGGAATA GCTTCCCGTT CAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PCDHB6 ( NM_001303145.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001290074.1 Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu69941
Clone ID Related Accession (Same CDS sequence)	NM_001303145.1 , NM_001303145.2
Accession Version	NM_001303145.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1977bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-28
Organism	Homo sapiens(human)
Product	protocadherin beta-6 isoform 2
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA789782.1, AK299661.1, AF152499.1, DA386733.1 and AF217752.1. On Jun 2, 2019 this sequence version replaced NM_001303145.1. Transcript Variant: This variant (2) lacks a portion of the 5' region and initiates translation at a downstream in-frame start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK299661.1, DC375688.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2153307 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCTCCTGA AAATATCAGA AATTACTATG CCAGGAAAGA TATTTCCTTT GAAAATGGCA 
CACGATTTAG ACACCGGCAG CAACGGCCTT CAGAGGTACA CAATCAGCTC CAACCCTCAC 
TTCCACGTTC TCACCCGCAA TCGCAGCGAA GGCAGGAAGT TCCCGGAGCT GGTGCTAGAC 
AAACCGTTGG ACCGCGAGGA GCAGCCCCAA CTCAGGCTAA CGCTGATCGC GCTGGATGGC 
GGGTCTCCGC CCCGGTCAGG GACCTCCGAG ATTCAGATCC AGGTTTTGGA CATCAATGAC 
AACGTCCCCG AGTTTGCTCA GGAGCTCTAT GAAGCACAAG TCCCTGAGAA CAACCCCCTC 
GGCTCTCTGG TTATTACCGT CTCAGCCAGA GATTTAGATG CAGGATCGTT TGGGAAGGTA 
TCTTACGCCC TGTTTCAAGT CGATGACGTC AACCAACCCT TCGAAATAAA CGCAATCACA 
GGAGAAATTC GGCTGAGAAA GGCTTTGGAT TTTGAGGAAA TTCAGTCTTA TGACGTGGAT 
GTTGAGGCTA CAGATGGTGG AGGCCTATCA GGAAAATGCT CTTTAGTCGT CAGGGTCCTG 
GACGTGAATG ACAATGCCCC TGAACTCACC ATGTCGTTCT TCATCAGCCT CATCCCAGAA 
AACTTACCAG AGATCACAGT GGCAGTTTTC AGTGTTTCAG ATGCAGACTC TGGACATAAC 
CAACAGGTTA TTTGTTCAAT AGAGAACAAT CTCCCCTTTC TACTAAGACC TTCCGTGGAG 
AATTTCTACA CCCTGGTAAC AGAAGGCGCG CTGGACAGAG AGAGCAGAGC CGAGTACAAC 
ATCACTATCA CGGTCACTGA TTTGGGGACA CCAAGGCTGA AAACCCAGCA GAGCATAACT 
GTGCAGGTCT CCGACGTCAA TGACAACGCC CCCGCCTTCA CCCAAACCTC CTACACCCTG 
TTCGTCCGCG AGAACAACAG CCCCGCCCTG CACATCGGCA GCGTCAGCGC CACAGACAGA 
GACTCAGGCA TCAACGCCCA GGTCACCTAC TCGCTGCTGC CGCCCCAGGA CCCGCACCTG 
CCCCTCTCTT CCCTGGTCTC CATCAACGCG GACAACGGCC ACCTGTTTGC CCTCAGGTCG 
CTGGACTACG AGGCCCTGCA GTCTTTCGAG TTCCGCGTGG GCGCCACAGA CCGCGGCTCC 
CCGGCGTTGA GCAGCGAGGC GCTGGTGCGC TTGCTGGTGC TGGACGCCAA CGACAACTCG 
CCCTTCGTGT TGTACCCGCT GCAGAACGGC TCCGCGCCCT GCACCGAGCT GGTGCCCCGG 
GCGGCCGAGC CGGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGGCGA CTCGGGCCAG 
AACGCCTGGC TGTCGTACCA GCTGCTCAAG GCCACGGAGC TCGGTCTGTT CGGCGTGTGG 
GCGCACAATG GCGAGGTGCG CACCGCCAGG CTGCTGAGCG AGCGAGACGC AGCCAAGCAC 
AGGCTGGTGG TGCTTGTCAA GGACAATGGC GAGCCTCCGC GCTCGGCCAC CGCCACGCTG 
CACGTGCTCC TGGTGGACGG CTTCTCCCAG CCCTACCTGC CTCTCCCTGA GGCGGCCCCG 
GCCCAAGCCC AGGCCGACTC TCTCACCGTC TACCTGGTGG TGGCGTTGGC CTCGGTGTCG 
TCGCTCTTCC TCTTTTCGGT GCTCCTGTTC GTGGCGGTGC GGCTGTGCAG GAGGAGCAGG 
GCGGCCTCGG TGGGTCGCTA CTCGGTGCCC GAGGGTCCCT TTCCAGGGCA TCTGGTGGAT 
GTGAGCGGCA CCGGGACCCT ATCCCAGAGC TACCAGTACA AGGTGTGTCT GACGGGAGGC 
TCAGAAACAA ATGAGTTCAA GTTCCTGAAG CCGATTATGC CCAACTTCCC TCCTCAGGGC 
ACTGAGAGAG AAATGGAAGA AACCCCCACC TCTCGGAATA GCTTCCCGTT CAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001290074.1
CDS	405..2381
Translation	MLLKISEITMPGKIFPLKMAHDLDTGSNGLQRYTISSNPHFHVLTRNRSEGRKFPELVLDKPLDREEQPQLRLTLIALDGGSPPRSGTSEIQIQVLDINDNVPEFAQELYEAQVPENNPLGSLVITVSARDLDAGSFGKVSYALFQVDDVNQPFEINAITGEIRLRKALDFEEIQSYDVDVEATDGGGLSGKCSLVVRVLDVNDNAPELTMSFFISLIPENLPEITVAVFSVSDADSGHNQQVICSIENNLPFLLRPSVENFYTLVTEGALDRESRAEYNITITVTDLGTPRLKTQQSITVQVSDVNDNAPAFTQTSYTLFVRENNSPALHIGSVSATDRDSGINAQVTYSLLPPQDPHLPLSSLVSINADNGHLFALRSLDYEALQSFEFRVGATDRGSPALSSEALVRLLVLDANDNSPFVLYPLQNGSAPCTELVPRAAEPGYLVTKVVAVDGDSGQNAWLSYQLLKATELGLFGVWAHNGEVRTARLLSERDAAKHRLVVLVKDNGEPPRSATATLHVLLVDGFSQPYLPLPEAAPAQAQADSLTVYLVVALASVSSLFLFSVLLFVAVRLCRRSRAASVGRYSVPEGPFPGHLVDVSGTGTLSQSYQYKVCLTGGSETNEFKFLKPIMPNFPPQGTEREMEETPTSRNSFPFS

Target ORF information:

RefSeq Version	NM_001303145.2
Organism	Homo sapiens(human)
Definition	Homo sapiens protocadherin beta 6 (PCDHB6), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001303145.2

ORF Insert Sequence:

ATGCTCCTGA AAATATCAGA AATTACTATG CCAGGAAAGA TATTTCCTTT GAAAATGGCA 
CACGATTTAG ACACCGGCAG CAACGGCCTT CAGAGGTACA CAATCAGCTC CAACCCTCAC 
TTCCACGTTC TCACCCGCAA TCGCAGCGAA GGCAGGAAGT TCCCGGAGCT GGTGCTAGAC 
AAACCGTTGG ACCGCGAGGA GCAGCCCCAA CTCAGGCTAA CGCTGATCGC GCTGGATGGC 
GGGTCTCCGC CCCGGTCAGG GACCTCCGAG ATTCAGATCC AGGTTTTGGA CATCAATGAC 
AACGTCCCCG AGTTTGCTCA GGAGCTCTAT GAAGCACAAG TCCCTGAGAA CAACCCCCTC 
GGCTCTCTGG TTATTACCGT CTCAGCCAGA GATTTAGATG CAGGATCGTT TGGGAAGGTA 
TCTTACGCCC TGTTTCAAGT CGATGACGTC AACCAACCCT TCGAAATAAA CGCAATCACA 
GGAGAAATTC GGCTGAGAAA GGCTTTGGAT TTTGAGGAAA TTCAGTCTTA TGACGTGGAT 
GTTGAGGCTA CAGATGGTGG AGGCCTATCA GGAAAATGCT CTTTAGTCGT CAGGGTCCTG 
GACGTGAATG ACAATGCCCC TGAACTCACC ATGTCGTTCT TCATCAGCCT CATCCCAGAA 
AACTTACCAG AGATCACAGT GGCAGTTTTC AGTGTTTCAG ATGCAGACTC TGGACATAAC 
CAACAGGTTA TTTGTTCAAT AGAGAACAAT CTCCCCTTTC TACTAAGACC TTCCGTGGAG 
AATTTCTACA CCCTGGTAAC AGAAGGCGCG CTGGACAGAG AGAGCAGAGC CGAGTACAAC 
ATCACTATCA CGGTCACTGA TTTGGGGACA CCAAGGCTGA AAACCCAGCA GAGCATAACT 
GTGCAGGTCT CCGACGTCAA TGACAACGCC CCCGCCTTCA CCCAAACCTC CTACACCCTG 
TTCGTCCGCG AGAACAACAG CCCCGCCCTG CACATCGGCA GCGTCAGCGC CACAGACAGA 
GACTCAGGCA TCAACGCCCA GGTCACCTAC TCGCTGCTGC CGCCCCAGGA CCCGCACCTG 
CCCCTCTCTT CCCTGGTCTC CATCAACGCG GACAACGGCC ACCTGTTTGC CCTCAGGTCG 
CTGGACTACG AGGCCCTGCA GTCTTTCGAG TTCCGCGTGG GCGCCACAGA CCGCGGCTCC 
CCGGCGTTGA GCAGCGAGGC GCTGGTGCGC TTGCTGGTGC TGGACGCCAA CGACAACTCG 
CCCTTCGTGT TGTACCCGCT GCAGAACGGC TCCGCGCCCT GCACCGAGCT GGTGCCCCGG 
GCGGCCGAGC CGGGCTACCT GGTGACCAAG GTGGTGGCGG TGGACGGCGA CTCGGGCCAG 
AACGCCTGGC TGTCGTACCA GCTGCTCAAG GCCACGGAGC TCGGTCTGTT CGGCGTGTGG 
GCGCACAATG GCGAGGTGCG CACCGCCAGG CTGCTGAGCG AGCGAGACGC AGCCAAGCAC 
AGGCTGGTGG TGCTTGTCAA GGACAATGGC GAGCCTCCGC GCTCGGCCAC CGCCACGCTG 
CACGTGCTCC TGGTGGACGG CTTCTCCCAG CCCTACCTGC CTCTCCCTGA GGCGGCCCCG 
GCCCAAGCCC AGGCCGACTC TCTCACCGTC TACCTGGTGG TGGCGTTGGC CTCGGTGTCG 
TCGCTCTTCC TCTTTTCGGT GCTCCTGTTC GTGGCGGTGC GGCTGTGCAG GAGGAGCAGG 
GCGGCCTCGG TGGGTCGCTA CTCGGTGCCC GAGGGTCCCT TTCCAGGGCA TCTGGTGGAT 
GTGAGCGGCA CCGGGACCCT ATCCCAGAGC TACCAGTACA AGGTGTGTCT GACGGGAGGC 
TCAGAAACAA ATGAGTTCAA GTTCCTGAAG CCGATTATGC CCAACTTCCC TCCTCAGGGC 
ACTGAGAGAG AAATGGAAGA AACCCCCACC TCTCGGAATA GCTTCCCGTT CAGTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Protocadherins.
Current opinion in cell biology14(5)557-62(2002 Oct)
Frank M,Kemler R

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.
FEBS letters495(1-2)120-5(2001 Apr)
Vanhalst K,Kools P,Vanden Eynde E,van Roy F

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.
Genome research11(3)389-404(2001 Mar)
Wu Q,Zhang T,Cheng JF,Kim Y,Grimwood J,Schmutz J,Dickson M,Noonan JP,Zhang MQ,Myers RM,Maniatis T

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.
Journal of molecular biology299(3)551-72(2000 Jun)
Nollet F,Kools P,van Roy F

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.
Genes & development14(10)1169-80(2000 May)
Yagi T,Takeichi M

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PCDHB6 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

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Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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