TMEM165 cDNA ORF clone, Homo sapiens(Human)

Gene
Clones
gRNAs

Summary

Gene Symbol	TMEM165
Entrez Gene ID	55858
Full Name	transmembrane protein 165
Synonyms	CDG2K,FT27,GDT1,TMPT27,TPARL
General protein information	Preferred Names transmembrane protein 165 Names transmembrane protein 165 TPA regulated locus transmembrane protein PT27 transmembrane protein TPARL
Gene Type	protein-coding
Organism	Homo sapiens(Human)
Genome	Chromosome: 4 Map Location: 4q12
Summary	This gene encodes a predicted transmembrane protein with a perinuclear Golgi-like distribution in fibroblasts. Mutations in this gene are associated with the autosomal recessive disorder congenital disorder of glycosylation, type IIk. Knockdown of this gene's expression causes decreased sialylation in HEK cells and suggests this gene plays a role in terminal Golgi glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012].
Disorder MIM:	614726
Disorder Html:	Congenital disorder of glycosylation, type IIk, 614727 (3)

mRNA and Protein(s)

mRNA	Protein	Name
NM_018475.5	NP_060945.2	transmembrane protein 165 precursor
XM_011534394.2	XP_011532696.1	transmembrane protein 165 isoform X1
NM_018475.4	NP_060945.2	transmembrane protein 165 precursor
XM_011534394.3	XP_011532696.1	transmembrane protein 165 isoform X1
XM_017008412.1	XP_016863901.1	transmembrane protein 165 isoform X2
XM_011534394.1	XP_011532696.1	transmembrane protein 165 isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TMEM165	XP_532375.2
Rattus norvegicus (Norway rat)	LOC100911646	XP_003751403.1
Gallus gallus (chicken)	TMEM165	XP_426336.3
Danio rerio (zebrafish)	tmem165	NP_997848.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP011962	XP_320572.4
Magnaporthe oryzae (rice blast fungus)	MGG_12672	XP_003721267.1
Pan troglodytes (chimpanzee)	TMEM165	XP_001145009.1
Saccharomyces cerevisiae (baker's yeast)	GDT1	NP_009746.1
Oryza sativa (rice)	Os08g0528500	NP_001062312.1
Oryza sativa (rice)	Os11g0472500	NP_001067880.1
Xenopus tropicalis (tropical clawed frog)	tmem165	NP_001017260.1
Homo sapiens (human)	TMEM165	NP_060945.2
Caenorhabditis elegans (roundworm)	CELE_Y54F10AL.1	NP_497567.1
Kluyveromyces lactis	KLLA0E23761g	XP_455024.1
Mus musculus (house mouse)	Tmem165	NP_035756.2
Rattus norvegicus (Norway rat)	Tmem165	NP_001019973.1
	TMEM165	XP_001088728.1
Bos taurus (cattle)	TMEM165	NP_001192935.1
Drosophila melanogaster (fruit fly)	CG42542	NP_001163615.1
Eremothecium gossypii	AGOS_AEL257W	NP_984604.1
Neurospora crassa	NCU01990	XP_964855.2
Arabidopsis thaliana (thale cress)	AT5G36290	NP_851098.1

Gene Ontology
Bibliography

Related articles in PubMed

Evidence for splice transcript variants of TMEM165, a gene involved in CDG.
Krzewinski-Recchi MA, Potelle S, Mir AM, Vicogne D, Dulary E, Duvet S, Morelle W, de Bettignies G, Foulquier F
Biochimica et biophysica acta1861(4)737-748(2017 04)

Manganese-induced turnover of TMEM165.
Potelle S, Dulary E, Climer L, Duvet S, Morelle W, Vicogne D, Lebredonchel E, Houdou M, Spriet C, Krzewinski-Recchi MA, Peanne R, Klein A, de Bettignies G, Morsomme P, Matthijs G, Marquardt T, Lupashin V, Foulquier F
The Biochemical journal474(9)1481-1493(2017 04)

TMEM165 deficiencies in Congenital Disorders of Glycosylation type II (CDG-II): Clues and evidences for roles of the protein in Golgi functions and ion homeostasis.
Dulary E, Potelle S, Legrand D, Foulquier F
Tissue & cell49(2 Pt A)150-156(2017 Apr)

Glycosylation abnormalities in Gdt1p/TMEM165 deficient cells result from a defect in Golgi manganese homeostasis.
Potelle S, Morelle W, Dulary E, Duvet S, Vicogne D, Spriet C, Krzewinski-Recchi MA, Morsomme P, Jaeken J, Matthijs G, De Bettignies G, Foulquier F
Human molecular genetics25(8)1489-500(2016 Apr)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The finding of numerous splice variants could lead to a family of TMEM165 isoforms.
Title: Evidence for splice transcript variants of TMEM165, a gene involved in CDG.

Data indicate the Golgi protein transmembrane protein 165 (TMEM165) as a manganese-sensitive protein in mammalian cells.
Title: Manganese-induced turnover of TMEM165.

This manuscript is a review of the current state of knowledge on TMEM165 deficiencies in Congenital Disorders of Glycosylation as well as new data on function of TMEM165 and some speculative models on TMEM165/Golgi functions are discussed.
Title: TMEM165 deficiencies in Congenital Disorders of Glycosylation type II (CDG-II): Clues and evidences for roles of the protein in Golgi functions and ion homeostasis.

Study not only provides novel insights into the molecular causes of glycosylation defects observed in TMEM165-deficient cells but also suggests that TMEM165 is a key determinant for the regulation of Golgi Mn(2+) homeostasis.
Title: Glycosylation abnormalities in Gdt1p/TMEM165 deficient cells result from a defect in Golgi manganese homeostasis.

Antisense oligonucleotide-mediated pseudoexon skipping used in a Golgi-resident protein, a promising treatment option for a specific TMEM165-congenital disorders of glycosylation.
Title: Antisense-mediated therapeutic pseudoexon skipping in TMEM165-CDG.

The following TMEM165 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TMEM165 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu19843	NM_018475.5 Latest version!	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu69858	XM_011534394.3 Latest version!	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu95307	XM_017008412.1 Latest version!	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00
View Old Accession Versions >>
OHu19843	NM_018475.4	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$154.50-$216.30 $309.00
OHu69858	XM_011534394.2	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
OHu69858	XM_011534394.1	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$99.50-$139.30 $199.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TMEM165 ( NM_018475.5 ) cDNA ORF clone, Homo sapiens(Human) -> NP_060945.2 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19843
Clone ID Related Accession (Same CDS sequence)	NM_018475.5 , NM_018475.4
Accession Version	NM_018475.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-21
Organism	Homo sapiens(human)
Product	transmembrane protein 165 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY089602.1, BC107582.1 and AF183409.1. This sequence is a reference standard in the RefSeqGene project. On Nov 22, 2018 this sequence version replaced NM_018475.4. Transcript Variant: This variant (1) represents the shorter transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.222347.1, BC107582.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000381334.10/ ENSP00000370736.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGTG 
ACAATCATAG GAGGCATCGT TTTTTTGGCG TTTGCATTTT CTGCACTATT TATAAGCCCT 
GATTCTGGTT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060945.2
CDS	234..1208
Translation	MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPDSGF

Target ORF information:

RefSeq Version	NM_018475.5
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018475.5

ORF Insert Sequence:

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGTG 
ACAATCATAG GAGGCATCGT TTTTTTGGCG TTTGCATTTT CTGCACTATT TATAAGCCCT 
GATTCTGGTT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM165 ( NM_018475.4 ) cDNA ORF clone, Homo sapiens(Human) -> NP_060945.2 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu19843
Clone ID Related Accession (Same CDS sequence)	NM_018475.5 , NM_018475.4
Accession Version	NM_018475.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 975bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-27
Organism	Homo sapiens(human)
Product	transmembrane protein 165 precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from HY089602.1, BC107582.1 and AF183409.1. This sequence is a reference standard in the RefSeqGene project. On Jul 28, 2012 this sequence version replaced NM_018475.3. Transcript Variant: This variant (1) represents the shorter transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.222347.1, SRR1163658.147219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGTG 
ACAATCATAG GAGGCATCGT TTTTTTGGCG TTTGCATTTT CTGCACTATT TATAAGCCCT 
GATTCTGGTT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060945.2
CDS	278..1252
Translation	MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPDSGF

Target ORF information:

RefSeq Version	NM_018475.4
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_018475.4

ORF Insert Sequence:

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGTG 
ACAATCATAG GAGGCATCGT TTTTTTGGCG TTTGCATTTT CTGCACTATT TATAAGCCCT 
GATTCTGGTT TTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM165 ( XM_011534394.2 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011532696.1 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69858
Clone ID Related Accession (Same CDS sequence)	XM_011534394.2 , XM_011534394.3 , XM_011534394.1
Accession Version	XM_011534394.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2016-06-05
Organism	Homo sapiens(human)
Product	transmembrane protein 165 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011534394.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532696.1
CDS	268..1233
Translation	MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTGSFSPWLILHACSDGKGHLERN

Target ORF information:

RefSeq Version	XM_011534394.2
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534394.2

ORF Insert Sequence:

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM165 ( XM_011534394.3 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011532696.1 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

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CloneID	OHu69858
Clone ID Related Accession (Same CDS sequence)	XM_011534394.2 , XM_011534394.3 , XM_011534394.1
Accession Version	XM_011534394.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 165 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011534394.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532696.1
CDS	237..1202
Translation	MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTGSFSPWLILHACSDGKGHLERN

Target ORF information:

RefSeq Version	XM_011534394.3
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534394.3

ORF Insert Sequence:

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM165 ( XM_011534394.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_011532696.1 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu69858
Clone ID Related Accession (Same CDS sequence)	XM_011534394.2 , XM_011534394.3 , XM_011534394.1
Accession Version	XM_011534394.1	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 966bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-03-11
Organism	Homo sapiens(Human)
Product	transmembrane protein 165 isoform X1
Comment

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_011532696.1
Translation	MAAAAPGNGRASAPRLLLLFLVPLLWAPAAVRAGPDEDLSHRNKEPPAPAQQLQPQPVAVQGPEPARVEKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTGSFSPWLILHACSDGKGHLERN

Target ORF information:

RefSeq Version	XM_011534394.1
Organism	Homo sapiens(Human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_011534394.1

ORF Insert Sequence:

ATGGCGGCCG CGGCTCCAGG GAACGGCCGC GCATCGGCGC CCCGGCTGCT TCTGCTCTTT 
CTGGTTCCGC TGCTGTGGGC CCCGGCTGCG GTCCGGGCCG GCCCAGATGA AGACCTTAGC 
CACCGGAACA AAGAACCGCC GGCGCCGGCC CAGCAGCTGC AGCCGCAGCC TGTGGCTGTG 
CAGGGCCCCG AGCCGGCCCG GGTCGAGAAA ATATTTACAC CAGCAGCTCC AGTTCATACC 
AATAAAGAAG ATCCTGCTAC CCAAACTAAT TTGGGATTTA TCCATGCATT TGTCGCTGCC 
ATATCAGTTA TTATTGTATC TGAATTGGGT GATAAGACAT TTTTTATAGC AGCCATCATG 
GCAATGCGCT ATAACCGCCT GACCGTGCTG GCTGGTGCAA TGCTTGCCTT GGGACTAATG 
ACATGCTTGT CAGTTTTGTT TGGCTATGCC ACCACAGTCA TCCCCAGGGT CTATACATAC 
TATGTTTCAA CTGTATTATT TGCCATTTTT GGCATTAGAA TGCTTCGGGA AGGCTTAAAG 
ATGAGCCCTG ATGAGGGTCA AGAGGAACTG GAAGAAGTTC AAGCTGAATT AAAGAAGAAA 
GATGAAGAAT TTCAACGAAC CAAACTTTTA AATGGACCGG GAGATGTTGA AACGGGTACA 
AGCATAACAG TACCTCAGAA AAAGTGGTTG CATTTTATTT CACCCATTTT TGTTCAAGCT 
CTTACATTAA CATTCTTAGC AGAATGGGGT GATCGCTCTC AACTAACTAC AATTGTATTG 
GCAGCTAGAG AGGACCCCTA TGGTGTAGCC GTGGGTGGAA CTGTGGGGCA CTGCCTGTGC 
ACGGGATTGG CAGTAATTGG AGGAAGAATG ATAGCACAGA AAATCTCTGT CAGAACTGGT 
AGTTTCTCTC CCTGGCTCAT CTTGCATGCT TGCTCTGATG GAAAAGGTCA CCTGGAAAGG 
AACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

TMEM165 ( XM_017008412.1 ) cDNA ORF clone, Homo sapiens(Human) -> XP_016863901.1 Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X3, mRNA.

Price & Availability↑

CloneID	OHu95307
Clone ID Related Accession (Same CDS sequence)	XM_017008412.1
Accession Version	XM_017008412.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 786bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	transmembrane protein 165 isoform X2
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000004.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGGAGATTC CGATGCAGAA AATATTTACA CCAGCAGCTC CAGTTCATAC CAATAAAGAA 
GATCCTGCTA CCCAAACTAA TTTGGGATTT ATCCATGCAT TTGTCGCTGC CATATCAGTT 
ATTATTGTAT CTGAATTGGG TGATAAGACA TTTTTTATAG CAGCCATCAT GGCAATGCGC 
TATAACCGCC TGACCGTGCT GGCTGGTGCA ATGCTTGCCT TGGGACTAAT GACATGCTTG 
TCAGTTTTGT TTGGCTATGC CACCACAGTC ATCCCCAGGG TCTATACATA CTATGTTTCA 
ACTGTATTAT TTGCCATTTT TGGCATTAGA ATGCTTCGGG AAGGCTTAAA GATGAGCCCT 
GATGAGGGTC AAGAGGAACT GGAAGAAGTT CAAGCTGAAT TAAAGAAGAA AGATGAAGAA 
TTTCAACGAA CCAAACTTTT AAATGGACCG GGAGATGTTG AAACGGGTAC AAGCATAACA 
GTACCTCAGA AAAAGTGGTT GCATTTTATT TCACCCATTT TTGTTCAAGC TCTTACATTA 
ACATTCTTAG CAGAATGGGG TGATCGCTCT CAACTAACTA CAATTGTATT GGCAGCTAGA 
GAGGACCCCT ATGGTGTAGC CGTGGGTGGA ACTGTGGGGC ACTGCCTGTG CACGGGATTG 
GCAGTAATTG GAGGAAGAAT GATAGCACAG AAAATCTCTG TCAGAACTGT GACAATCATA 
GGAGGCATCG TTTTTTTGGC GTTTGCATTT TCTGCACTAT TTATAAGCCC TGATTCTGGT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_016863901.1
CDS	385..1170
Translation	MEIPMQKIFTPAAPVHTNKEDPATQTNLGFIHAFVAAISVIIVSELGDKTFFIAAIMAMRYNRLTVLAGAMLALGLMTCLSVLFGYATTVIPRVYTYYVSTVLFAIFGIRMLREGLKMSPDEGQEELEEVQAELKKKDEEFQRTKLLNGPGDVETGTSITVPQKKWLHFISPIFVQALTLTFLAEWGDRSQLTTIVLAAREDPYGVAVGGTVGHCLCTGLAVIGGRMIAQKISVRTVTIIGGIVFLAFAFSALFISPDSGF

Target ORF information:

RefSeq Version	XM_017008412.1
Organism	Homo sapiens(human)
Definition	Homo sapiens transmembrane protein 165 (TMEM165), transcript variant X3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_017008412.1

ORF Insert Sequence:

ATGGAGATTC CGATGCAGAA AATATTTACA CCAGCAGCTC CAGTTCATAC CAATAAAGAA 
GATCCTGCTA CCCAAACTAA TTTGGGATTT ATCCATGCAT TTGTCGCTGC CATATCAGTT 
ATTATTGTAT CTGAATTGGG TGATAAGACA TTTTTTATAG CAGCCATCAT GGCAATGCGC 
TATAACCGCC TGACCGTGCT GGCTGGTGCA ATGCTTGCCT TGGGACTAAT GACATGCTTG 
TCAGTTTTGT TTGGCTATGC CACCACAGTC ATCCCCAGGG TCTATACATA CTATGTTTCA 
ACTGTATTAT TTGCCATTTT TGGCATTAGA ATGCTTCGGG AAGGCTTAAA GATGAGCCCT 
GATGAGGGTC AAGAGGAACT GGAAGAAGTT CAAGCTGAAT TAAAGAAGAA AGATGAAGAA 
TTTCAACGAA CCAAACTTTT AAATGGACCG GGAGATGTTG AAACGGGTAC AAGCATAACA 
GTACCTCAGA AAAAGTGGTT GCATTTTATT TCACCCATTT TTGTTCAAGC TCTTACATTA 
ACATTCTTAG CAGAATGGGG TGATCGCTCT CAACTAACTA CAATTGTATT GGCAGCTAGA 
GAGGACCCCT ATGGTGTAGC CGTGGGTGGA ACTGTGGGGC ACTGCCTGTG CACGGGATTG 
GCAGTAATTG GAGGAAGAAT GATAGCACAG AAAATCTCTG TCAGAACTGT GACAATCATA 
GGAGGCATCG TTTTTTTGGC GTTTGCATTT TCTGCACTAT TTATAAGCCC TGATTCTGGT 
TTTTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Evidence for splice transcript variants of TMEM165, a gene involved in CDG.
Biochimica et biophysica acta1861(4)737-748(2017 04)
Krzewinski-Recchi MA,Potelle S,Mir AM,Vicogne D,Dulary E,Duvet S,Morelle W,de Bettignies G,Foulquier F

Manganese-induced turnover of TMEM165.
The Biochemical journal474(9)1481-1493(2017 04)
Potelle S,Dulary E,Climer L,Duvet S,Morelle W,Vicogne D,Lebredonchel E,Houdou M,Spriet C,Krzewinski-Recchi MA,Peanne R,Klein A,de Bettignies G,Morsomme P,Matthijs G,Marquardt T,Lupashin V,Foulquier F

TMEM165 deficiencies in Congenital Disorders of Glycosylation type II (CDG-II): Clues and evidences for roles of the protein in Golgi functions and ion homeostasis.
Tissue & cell49(2 Pt A)150-156(2017 Apr)
Dulary E,Potelle S,Legrand D,Foulquier F

Glycosylation abnormalities in Gdt1p/TMEM165 deficient cells result from a defect in Golgi manganese homeostasis.
Human molecular genetics25(8)1489-500(2016 Apr)
Potelle S,Morelle W,Dulary E,Duvet S,Vicogne D,Spriet C,Krzewinski-Recchi MA,Morsomme P,Jaeken J,Matthijs G,De Bettignies G,Foulquier F

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TMEM165 cDNA ORF clone, Homo sapiens(Human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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