UBE2Q1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	UBE2Q1
Entrez Gene ID	55585
Full Name	ubiquitin conjugating enzyme E2 Q1
Synonyms	GTAP,NICE-5,NICE5,PRO3094,UBE2Q
General protein information	Preferred Names ubiquitin conjugating enzyme E2 Q1 Names ubiquitin-conjugating enzyme E2 Q1 E2 ubiquitin-conjugating enzyme Q1 galactosyl transferase-associated protein protein NICE-5 ubiquitin carrier protein Q1 ubiquitin conjugating enzyme E2Q family member 1 ubiquitin-conjugating enzyme E2Q (putative) 1 ubiquitin-protein ligase Q1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 1 Map Location: 1q21.3
Summary	The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is 98% identical to the mouse counterpart. [provided by RefSeq, Jul 2008].
Disorder MIM:	617429

mRNA and Protein(s)

mRNA	Protein	Name
NM_017582.7	NP_060052.3	ubiquitin-conjugating enzyme E2 Q1
NM_017582.6	NP_060052.3	ubiquitin-conjugating enzyme E2 Q1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	UBE2Q1	XP_001152268.1
Canis lupus familiaris (dog)	UBE2Q1	XP_003434990.1
Bos taurus (cattle)	UBE2Q1	NP_001193249.1
Mus musculus (house mouse)	Ube2q1	NP_081591.3
Rattus norvegicus (Norway rat)	Ube2q1	NP_001099918.1
Homo sapiens (human)	UBE2Q1	NP_060052.3
Gallus gallus (chicken)	LOC100858564	XP_003643415.2

Gene Ontology
Bibliography

Related articles in PubMed

Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through ?-catenin-EGFR-PI3K-Akt-mTOR signaling pathway.
Zhang B, Deng C, Wang L, Zhou F, Zhang S, Kang W, Zhan P, Chen J, Shen S, Guo H, Zhang M, Wang Y, Zhang F, Zhang W, Xiao J, Kong B, Friess H, Zhuge Y, Yan H, Zou X
Molecular carcinogenesis57(2)201-215(2018 Feb)

Hypomethylated Ubiquitin-Conjugating Enzyme2 Q1 (UBE2Q1) Gene Promoter in the Serum Is a Promising Biomarker for Hepatitis B Virus-Associated Hepatocellular Carcinoma.
Hu N, Fan XP, Fan YC, Chen LY, Qiao CY, Han LY, Wang K
The Tohoku journal of experimental medicine242(2)93-100(2017 06)

Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in ian Patients.
Mokarram P, Shakiba-Jam F, Kavousipour S, Sarabi MM, Seghatoleslam A
Asian Pacific journal of cancer prevention : APJCP16(18)8247-52(2015)

UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53.
Shafiee SM, Rasti M, Seghatoleslam A, Azimi T, Owji AA
Asian Pacific journal of cancer prevention : APJCP16(9)3723-7(2015)

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
Kauwe JS, Bailey MH, Ridge PG, Perry R, Wadsworth ME, Hoyt KL, Staley LA, Karch CM, Harari O, Cruchaga C, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, , Fagan AM, Holtzman DM, Morris JC, Goate AM
PLoS genetics10(10)e1004758(2014 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

These data imply that UBE2Q1 is upregulated in liver cancer cell lines and tumorous samples and may play a role in the development of HCC.
Title: Upregulated expression of ubiquitin-conjugating enzyme E2Q1 (UBE2Q1) is associated with enhanced cell proliferation and poor prognosis in human hapatocellular carcinoma.

UBE2Q1 hypermethylation is associated with Colorectal Cancer.
Title: Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in ian Patients.

overexpression of UBE2Q1 is associated with Breast Carcinoma.
Title: UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53.

UBE2Q1 is differentially expressed in colorectal cell lines and shows overexpression in colorectal tumors.
Title: UBE2Q1 expression in human colorectal tumors and cell lines.

This result along with the real-time PCR data shows that the novel human gene, UBE2Q1, is expressed in human breast and may have implications for pathogenesis of breast cancer.
Title: Expression of the novel human gene, UBE2Q1, in breast tumors.

The following UBE2Q1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UBE2Q1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu02865	NM_017582.7 Latest version!	Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$244.30 $349.00
View Old Accession Versions >>
OHu02865	NM_017582.6	Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$244.30 $349.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

UBE2Q1 ( NM_017582.7 ) cDNA ORF clone, Homo sapiens(human) -> NP_060052.3 Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.

Price & Availability↑

CloneID	OHu02865
Clone ID Related Accession (Same CDS sequence)	NM_017582.7 , NM_017582.6
Accession Version	NM_017582.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-02
Organism	Homo sapiens(human)
Product	ubiquitin-conjugating enzyme E2 Q1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL592078.10, CA391436.1 and AY112698.1. On Nov 23, 2018 this sequence version replaced NM_017582.6. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY112698.1, SRR1163657.455477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146, SAMEA2467147 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000292211.5/ ENSP00000292211.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGCAGCAGC CGCAGCCGCA GGGGCAGCAG CAGCCGGGGC CGGGGCAGCA GCTGGGGGGC 
CAGGGGGCGG CGCCGGGGGC CGGGGGCGGC CCAGGGGGGG GCCCGGGGCC GGGGCCCTGC 
CTGAGGCGAG AGCTGAAGCT GCTCGAGTCC ATCTTCCACC GCGGCCACGA GCGCTTCCGC 
ATTGCCAGCG CCTGCCTGGA CGAGCTGAGC TGCGAGTTCC TGCTGGCTGG GGCCGGAGGG 
GCCGGGGCGG GGGCCGCGCC CGGACCGCAT CTCCCCCCAC GGGGGTCGGT GCCTGGGGAT 
CCTGTCCGCA TCCACTGCAA CATCACGGAG TCATACCCTG CTGTGCCCCC CATCTGGTCG 
GTGGAGTCTG ATGACCCTAA CTTGGCTGCT GTCTTGGAGA GGCTGGTGGA CATAAAGAAA 
GGGAATACTC TGCTATTGCA GCATCTGAAG AGGATCATCT CCGACCTGTG TAAACTCTAT 
AACCTCCCTC AGCATCCAGA TGTGGAGATG CTGGATCAAC CCTTGCCAGC AGAGCAGTGC 
ACACAGGAAG ACGTGTCTTC AGAAGATGAA GATGAGGAGA TGCCTGAGGA CACAGAAGAC 
TTAGATCACT ATGAAATGAA AGAGGAAGAG CCAGCTGAGG GCAAGAAATC TGAAGATGAT 
GGCATTGGAA AAGAAAACTT GGCCATCCTA GAGAAAATTA AAAAGAACCA GAGGCAAGAT 
TACTTAAATG GTGCAGTGTC TGGCTCGGTG CAGGCCACTG ACCGGCTGAT GAAGGAGCTC 
AGGGATATAT ACCGATCACA GAGTTTCAAA GGCGGAAACT ATGCAGTCGA ACTCGTGAAT 
GACAGTCTGT ATGATTGGAA TGTCAAACTC CTCAAAGTTG ACCAGGACAG CGCTTTGCAC 
AACGATCTCC AGATCCTCAA AGAGAAAGAA GGAGCCGACT TCATTCTACT TAACTTTTCC 
TTTAAAGATA ACTTTCCCTT TGACCCACCA TTTGTCAGGG TTGTGTCTCC AGTCCTCTCT 
GGAGGGTATG TTCTGGGCGG AGGGGCCATC TGCATGGAAC TTCTCACCAA ACAGGGCTGG 
AGCAGTGCCT ACTCCATAGA GTCAGTGATC ATGCAGATCA GTGCCACACT GGTGAAGGGG 
AAAGCACGAG TGCAGTTTGG AGCCAACAAA TCTCAATACA GTCTGACAAG AGCACAGCAG 
TCCTACAAGT CCTTGGTGCA GATCCACGAA AAAAACGGCT GGTACACACC CCCAAAAGAA 
GACGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060052.3
CDS	110..1378
Translation	MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG

Target ORF information:

RefSeq Version	NM_017582.7
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017582.7

ORF Insert Sequence:

ATGCAGCAGC CGCAGCCGCA GGGGCAGCAG CAGCCGGGGC CGGGGCAGCA GCTGGGGGGC 
CAGGGGGCGG CGCCGGGGGC CGGGGGCGGC CCAGGGGGGG GCCCGGGGCC GGGGCCCTGC 
CTGAGGCGAG AGCTGAAGCT GCTCGAGTCC ATCTTCCACC GCGGCCACGA GCGCTTCCGC 
ATTGCCAGCG CCTGCCTGGA CGAGCTGAGC TGCGAGTTCC TGCTGGCTGG GGCCGGAGGG 
GCCGGGGCGG GGGCCGCGCC CGGACCGCAT CTCCCCCCAC GGGGGTCGGT GCCTGGGGAT 
CCTGTCCGCA TCCACTGCAA CATCACGGAG TCATACCCTG CTGTGCCCCC CATCTGGTCG 
GTGGAGTCTG ATGACCCTAA CTTGGCTGCT GTCTTGGAGA GGCTGGTGGA CATAAAGAAA 
GGGAATACTC TGCTATTGCA GCATCTGAAG AGGATCATCT CCGACCTGTG TAAACTCTAT 
AACCTCCCTC AGCATCCAGA TGTGGAGATG CTGGATCAAC CCTTGCCAGC AGAGCAGTGC 
ACACAGGAAG ACGTGTCTTC AGAAGATGAA GATGAGGAGA TGCCTGAGGA CACAGAAGAC 
TTAGATCACT ATGAAATGAA AGAGGAAGAG CCAGCTGAGG GCAAGAAATC TGAAGATGAT 
GGCATTGGAA AAGAAAACTT GGCCATCCTA GAGAAAATTA AAAAGAACCA GAGGCAAGAT 
TACTTAAATG GTGCAGTGTC TGGCTCGGTG CAGGCCACTG ACCGGCTGAT GAAGGAGCTC 
AGGGATATAT ACCGATCACA GAGTTTCAAA GGCGGAAACT ATGCAGTCGA ACTCGTGAAT 
GACAGTCTGT ATGATTGGAA TGTCAAACTC CTCAAAGTTG ACCAGGACAG CGCTTTGCAC 
AACGATCTCC AGATCCTCAA AGAGAAAGAA GGAGCCGACT TCATTCTACT TAACTTTTCC 
TTTAAAGATA ACTTTCCCTT TGACCCACCA TTTGTCAGGG TTGTGTCTCC AGTCCTCTCT 
GGAGGGTATG TTCTGGGCGG AGGGGCCATC TGCATGGAAC TTCTCACCAA ACAGGGCTGG 
AGCAGTGCCT ACTCCATAGA GTCAGTGATC ATGCAGATCA GTGCCACACT GGTGAAGGGG 
AAAGCACGAG TGCAGTTTGG AGCCAACAAA TCTCAATACA GTCTGACAAG AGCACAGCAG 
TCCTACAAGT CCTTGGTGCA GATCCACGAA AAAAACGGCT GGTACACACC CCCAAAAGAA 
GACGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

UBE2Q1 ( NM_017582.6 ) cDNA ORF clone, Homo sapiens(human) -> NP_060052.3 Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.

Price & Availability↑

CloneID	OHu02865
Clone ID Related Accession (Same CDS sequence)	NM_017582.7 , NM_017582.6
Accession Version	NM_017582.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1269bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-10-01
Organism	Homo sapiens(human)
Product	ubiquitin-conjugating enzyme E2 Q1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from CA391436.1, AY112698.1 and AL592078.10. On Aug 31, 2007 this sequence version replaced NM_017582.5. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY112698.1, SRR1163657.455477.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2467146, SAMEA2467147 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCAGCAGC CGCAGCCGCA GGGGCAGCAG CAGCCGGGGC CGGGGCAGCA GCTGGGGGGC 
CAGGGGGCGG CGCCGGGGGC CGGGGGCGGC CCAGGGGGGG GCCCGGGGCC GGGGCCCTGC 
CTGAGGCGAG AGCTGAAGCT GCTCGAGTCC ATCTTCCACC GCGGCCACGA GCGCTTCCGC 
ATTGCCAGCG CCTGCCTGGA CGAGCTGAGC TGCGAGTTCC TGCTGGCTGG GGCCGGAGGG 
GCCGGGGCGG GGGCCGCGCC CGGACCGCAT CTCCCCCCAC GGGGGTCGGT GCCTGGGGAT 
CCTGTCCGCA TCCACTGCAA CATCACGGAG TCATACCCTG CTGTGCCCCC CATCTGGTCG 
GTGGAGTCTG ATGACCCTAA CTTGGCTGCT GTCTTGGAGA GGCTGGTGGA CATAAAGAAA 
GGGAATACTC TGCTATTGCA GCATCTGAAG AGGATCATCT CCGACCTGTG TAAACTCTAT 
AACCTCCCTC AGCATCCAGA TGTGGAGATG CTGGATCAAC CCTTGCCAGC AGAGCAGTGC 
ACACAGGAAG ACGTGTCTTC AGAAGATGAA GATGAGGAGA TGCCTGAGGA CACAGAAGAC 
TTAGATCACT ATGAAATGAA AGAGGAAGAG CCAGCTGAGG GCAAGAAATC TGAAGATGAT 
GGCATTGGAA AAGAAAACTT GGCCATCCTA GAGAAAATTA AAAAGAACCA GAGGCAAGAT 
TACTTAAATG GTGCAGTGTC TGGCTCGGTG CAGGCCACTG ACCGGCTGAT GAAGGAGCTC 
AGGGATATAT ACCGATCACA GAGTTTCAAA GGCGGAAACT ATGCAGTCGA ACTCGTGAAT 
GACAGTCTGT ATGATTGGAA TGTCAAACTC CTCAAAGTTG ACCAGGACAG CGCTTTGCAC 
AACGATCTCC AGATCCTCAA AGAGAAAGAA GGAGCCGACT TCATTCTACT TAACTTTTCC 
TTTAAAGATA ACTTTCCCTT TGACCCACCA TTTGTCAGGG TTGTGTCTCC AGTCCTCTCT 
GGAGGGTATG TTCTGGGCGG AGGGGCCATC TGCATGGAAC TTCTCACCAA ACAGGGCTGG 
AGCAGTGCCT ACTCCATAGA GTCAGTGATC ATGCAGATCA GTGCCACACT GGTGAAGGGG 
AAAGCACGAG TGCAGTTTGG AGCCAACAAA TCTCAATACA GTCTGACAAG AGCACAGCAG 
TCCTACAAGT CCTTGGTGCA GATCCACGAA AAAAACGGCT GGTACACACC CCCAAAAGAA 
GACGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060052.3
CDS	92..1360
Translation	MQQPQPQGQQQPGPGQQLGGQGAAPGAGGGPGGGPGPGPCLRRELKLLESIFHRGHERFRIASACLDELSCEFLLAGAGGAGAGAAPGPHLPPRGSVPGDPVRIHCNITESYPAVPPIWSVESDDPNLAAVLERLVDIKKGNTLLLQHLKRIISDLCKLYNLPQHPDVEMLDQPLPAEQCTQEDVSSEDEDEEMPEDTEDLDHYEMKEEEPAEGKKSEDDGIGKENLAILEKIKKNQRQDYLNGAVSGSVQATDRLMKELRDIYRSQSFKGGNYAVELVNDSLYDWNVKLLKVDQDSALHNDLQILKEKEGADFILLNFSFKDNFPFDPPFVRVVSPVLSGGYVLGGGAICMELLTKQGWSSAYSIESVIMQISATLVKGKARVQFGANKSQYSLTRAQQSYKSLVQIHEKNGWYTPPKEDG

Target ORF information:

RefSeq Version	NM_017582.6
Organism	Homo sapiens(human)
Definition	Homo sapiens ubiquitin conjugating enzyme E2 Q1 (UBE2Q1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017582.6

ORF Insert Sequence:

ATGCAGCAGC CGCAGCCGCA GGGGCAGCAG CAGCCGGGGC CGGGGCAGCA GCTGGGGGGC 
CAGGGGGCGG CGCCGGGGGC CGGGGGCGGC CCAGGGGGGG GCCCGGGGCC GGGGCCCTGC 
CTGAGGCGAG AGCTGAAGCT GCTCGAGTCC ATCTTCCACC GCGGCCACGA GCGCTTCCGC 
ATTGCCAGCG CCTGCCTGGA CGAGCTGAGC TGCGAGTTCC TGCTGGCTGG GGCCGGAGGG 
GCCGGGGCGG GGGCCGCGCC CGGACCGCAT CTCCCCCCAC GGGGGTCGGT GCCTGGGGAT 
CCTGTCCGCA TCCACTGCAA CATCACGGAG TCATACCCTG CTGTGCCCCC CATCTGGTCG 
GTGGAGTCTG ATGACCCTAA CTTGGCTGCT GTCTTGGAGA GGCTGGTGGA CATAAAGAAA 
GGGAATACTC TGCTATTGCA GCATCTGAAG AGGATCATCT CCGACCTGTG TAAACTCTAT 
AACCTCCCTC AGCATCCAGA TGTGGAGATG CTGGATCAAC CCTTGCCAGC AGAGCAGTGC 
ACACAGGAAG ACGTGTCTTC AGAAGATGAA GATGAGGAGA TGCCTGAGGA CACAGAAGAC 
TTAGATCACT ATGAAATGAA AGAGGAAGAG CCAGCTGAGG GCAAGAAATC TGAAGATGAT 
GGCATTGGAA AAGAAAACTT GGCCATCCTA GAGAAAATTA AAAAGAACCA GAGGCAAGAT 
TACTTAAATG GTGCAGTGTC TGGCTCGGTG CAGGCCACTG ACCGGCTGAT GAAGGAGCTC 
AGGGATATAT ACCGATCACA GAGTTTCAAA GGCGGAAACT ATGCAGTCGA ACTCGTGAAT 
GACAGTCTGT ATGATTGGAA TGTCAAACTC CTCAAAGTTG ACCAGGACAG CGCTTTGCAC 
AACGATCTCC AGATCCTCAA AGAGAAAGAA GGAGCCGACT TCATTCTACT TAACTTTTCC 
TTTAAAGATA ACTTTCCCTT TGACCCACCA TTTGTCAGGG TTGTGTCTCC AGTCCTCTCT 
GGAGGGTATG TTCTGGGCGG AGGGGCCATC TGCATGGAAC TTCTCACCAA ACAGGGCTGG 
AGCAGTGCCT ACTCCATAGA GTCAGTGATC ATGCAGATCA GTGCCACACT GGTGAAGGGG 
AAAGCACGAG TGCAGTTTGG AGCCAACAAA TCTCAATACA GTCTGACAAG AGCACAGCAG 
TCCTACAAGT CCTTGGTGCA GATCCACGAA AAAAACGGCT GGTACACACC CCCAAAAGAA 
GACGGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Upregulation of UBE2Q1 via gene copy number gain in hepatocellular carcinoma promotes cancer progression through ?-catenin-EGFR-PI3K-Akt-mTOR signaling pathway.
Molecular carcinogenesis57(2)201-215(2018 Feb)
Zhang B,Deng C,Wang L,Zhou F,Zhang S,Kang W,Zhan P,Chen J,Shen S,Guo H,Zhang M,Wang Y,Zhang F,Zhang W,Xiao J,Kong B,Friess H,Zhuge Y,Yan H,Zou X

Hypomethylated Ubiquitin-Conjugating Enzyme2 Q1 (UBE2Q1) Gene Promoter in the Serum Is a Promising Biomarker for Hepatitis B Virus-Associated Hepatocellular Carcinoma.
The Tohoku journal of experimental medicine242(2)93-100(2017 06)
Hu N,Fan XP,Fan YC,Chen LY,Qiao CY,Han LY,Wang K

Promoter Methylation Status of Two Novel Human Genes, UBE2Q1 and UBE2Q2, in Colorectal Cancer: a New Finding in Iranian Patients.
Asian Pacific journal of cancer prevention : APJCP16(18)8247-52(2015)
Mokarram P,Shakiba-Jam F,Kavousipour S,Sarabi MM,Seghatoleslam A

UBE2Q1 in a Human Breast Carcinoma Cell Line: Overexpression and Interaction with p53.
Asian Pacific journal of cancer prevention : APJCP16(9)3723-7(2015)
Shafiee SM,Rasti M,Seghatoleslam A,Azimi T,Owji AA

Genome-wide association study of CSF levels of 59 alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation.
PLoS genetics10(10)e1004758(2014 Oct)
Kauwe JS,Bailey MH,Ridge PG,Perry R,Wadsworth ME,Hoyt KL,Staley LA,Karch CM,Harari O,Cruchaga C,Ainscough BJ,Bales K,Pickering EH,Bertelsen S,,Fagan AM,Holtzman DM,Morris JC,Goate AM

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UBE2Q1 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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