PRR5-ARHGAP8 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	PRR5-ARHGAP8
Entrez Gene ID	553158
Full Name	PRR5-ARHGAP8 readthrough
General protein information	Preferred Names PRR5-ARHGAP8 readthrough Names PRR5-ARHGAP8 fusion protein PRR5-ARHGAP8 fusion
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 22 Map Location: 22q13.31
Summary	The PRR5-ARHGAP8 mRNA is an infrequent but naturally occurring read-through transcript of the neighboring proline rich 5, renal (PRR5) and Rho GTPase activating protein 8 (ARHGAP8) genes. The resulting fusion protein contains sequence identity with each individual gene product, and it includes domains characteristic of a RhoGAP protein. The significance of this read-through transcript and the function of its protein product have not yet been determined. [provided by RefSeq, Nov 2010].

mRNA and Protein(s)

mRNA	Protein	Name
NM_181334.5	NP_851851.3	PRR5-ARHGAP8 fusion protein

Pathways from BioSystems

Homologies

Homo sapiens (human)	ARHGAP8	NP_851852.2
Canis lupus familiaris (dog)	ARHGAP8	NP_001191334.1
Mus musculus (house mouse)	Arhgap8	NP_082731.2
Gallus gallus (chicken)	ARHGAP8	NP_001191318.1
Pan troglodytes (chimpanzee)	ARHGAP8	XP_003317351.1
Homo sapiens (human)	PRR5-ARHGAP8	NP_851851.2
Rattus norvegicus (Norway rat)	Arhgap8	NP_001004242.1
Xenopus tropicalis (tropical clawed frog)	arhgap8	NP_001016951.1

Gene Ontology
Bibliography

Related articles in PubMed

Bipolar disorder with comorbid binge eating history: a genome-wide association study implicates APOB.
Winham SJ, Cuellar-Barboza AB, McElroy SL, Oliveros A, Crow S, Colby CL, Choi DS, Chauhan M, Frye MA, Biernacka JM
Journal of affective disorders165151-8(2014 Aug)

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y, Fujikake T, Takeda T, Taylor TD
PloS one5(10)e13284(2010 Oct)

PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas.
Johnstone CN, Castellv?-Bel S, Chang LM, Sung RK, Bowser MJ, Piqu? JM, Castells A, Rustgi AK
Genomics85(3)338-51(2005 Mar)

The DNA sequence of human chromosome 22.
Dunham I, Shimizu N, Roe BA, Chissoe S, Hunt AR, Collins JE, Bruskiewich R, Beare DM, Clamp M, Smink LJ, Ainscough R, Almeida JP, Babbage A, Bagguley C, Bailey J, Barlow K, Bates KN, Beasley O, Bird CP, Blakey S, Bridgeman AM, Buck D, Burgess J, Burrill WD, O'Brien KP
Nature402(6761)489-95(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

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The following PRR5-ARHGAP8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PRR5-ARHGAP8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu80446	NM_181334.5 Latest version!	Homo sapiens PRR5-ARHGAP8 readthrough (PRR5-ARHGAP8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$219.50-$307.30 $439.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PRR5-ARHGAP8 ( NM_181334.5 ) cDNA ORF clone, Homo sapiens(human) -> NP_851851.3 Homo sapiens PRR5-ARHGAP8 readthrough (PRR5-ARHGAP8), mRNA.

Price & Availability↑

CloneID	OHu80446
Clone ID Related Accession (Same CDS sequence)	NM_181334.5
Accession Version	NM_181334.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1695bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-30
Organism	Homo sapiens(human)
Product	PRR5-ARHGAP8 fusion protein
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from Z98743.1, BX335168.2, AF195968.1 and Z83838.2. This sequence is a reference standard in the RefSeqGene project. On Sep 26, 2014 this sequence version replaced NM_181334.4. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145313, SAMEA2146236 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 23779, 55615 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGGACTC TCCGCAGGTT GAAGTTCATG AGTTCGCCCA GCCTCAGTGA CCTGGGCAAG 
AGAGAGCCGG CCGCCGCCGC GGACGAGCGG GGCACGCAGC AGCGCCGGGC CTGCGCCAAC 
GCCACCTGGA ACAGCATCCA CAACGGGGTG ATCGCCGTCT TCCAGCGCAA GGGGCTGCCC 
GACCAGGAGC TCTTCAGCCT CAACGAGGGC GTCCGGCAGC TGTTGAAGAC AGAGCTGGGG 
TCCTTCTTCA CGGAGTACCT GCAGAACCAG CTGCTGACAA AAGGCATGGT GATCCTTCGG 
GACAAGATTC GCTTCTATGA GGAGCTGCAG AGAGACAAGG CGGCGGCGGC TGCTGTGCTG 
GGTGCAGTGA GGAAGAGGCC CTCGGTGGTG CCCATGGCTG GCCAGGATCC TGCGCTGAGC 
ACGAGTCACC CGTTCTACGA CGTGGCCAGA CATGGCATTC TGCAGGTGGC AGGGGATGAC 
CGCTTTGGAA GACGTGTTGT CACGTTCAGC TGCTGCCGGA TGCCACCCTC CCACGAGCTG 
GACCACCAGC GGCTGCTGGA GTATTTGAAG TACACACTGG ACCAATACGT TGAGAACGAT 
TATACCATCG TCTATTTCCA CTACGGGCTG AACAGCCGGA ACAAGCCTTC CCTGGGCTGG 
CTCCAGAGCG CATACAAGGA GTTCGATAGG AAGTACAAGA AGAACTTGAA GGCCCTCTAC 
GTGGTGCACC CCACCAGCTT CATCAAGGTC CTGTGGAACA TCTTGAAGCC CCTCATCAGT 
CACAAGTTTG GGAAGAAAGT CATCTATTTC AACTACCTGA GTGAGCTCCA CGAACACCTT 
AAATACGACC AGCTGGTCAT CCCTCCCGAA GTTTTGCGGT ACGATGAGAA GCTCCAGAGC 
CTGCACGAGG GCCGGACGCC GCCTCCCACC AAGACACCAC CGCCGCGGCC CCCGCTGCCC 
ACACAGCAGT TTGGCGTCAG TCTGCAATAC CTCAAAGACA AAAATCAAGG CGAACTCATC 
CCCCCTGTGC TGAGGTTCAC AGTGACGTAC CTGAGAGAGA AAGGCCTGCG CACCGAGGGC 
CTGTTCCGGA GATCCGCCAG CGTGCAGACC GTCCGCGAGA TCCAGAGGCT CTACAACCAA 
GGGAAGCCCG TGAACTTTGA CGACTACGGG GACATTCACA TCCCTGCCGT GATCCTGAAG 
ACCTTCCTGC GAGAGCTGCC CCAGCCGCTT CTGACCTTCC AGGCCTACGA GCAGATTCTC 
GGGATCACCT GTGTGGAGAG CAGCCTGCGT GTCACTGGCT GCCGCCAGAT CTTACGGAGC 
CTCCCAGAGC ACAACTACGT CGTCCTCCGC TACCTCATGG GCTTCCTGCA TGCGGTGTCC 
CGGGAGAGCA TCTTCAACAA AATGAACAGC TCTAACCTGG CCTGTGTCTT CGGGCTGAAT 
TTGATCTGGC CATCCCAGGG GGTCTCCTCC CTGAGTGCCC TTGTGCCCCT GAACATGTTC 
ACTGAACTGC TGATCGAGTA CTATGAAAAG ATCTTCAGCA CCCCGGAGGC ACCTGGGGAG 
CACGGCCTGG CACCATGGGA ACAGGGGAGC AGGGCAGCCC CTTTGCAGGA GGCTGTGCCA 
CGGACACAAG CCACGGGCCT CACCAAGCCT ACCCTACCTC CGAGTCCCCT GATGGCAGCC 
AGAAGACGTC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_851851.3
CDS	278..1972
Translation	MRTLRRLKFMSSPSLSDLGKREPAAAADERGTQQRRACANATWNSIHNGVIAVFQRKGLPDQELFSLNEGVRQLLKTELGSFFTEYLQNQLLTKGMVILRDKIRFYEELQRDKAAAAAVLGAVRKRPSVVPMAGQDPALSTSHPFYDVARHGILQVAGDDRFGRRVVTFSCCRMPPSHELDHQRLLEYLKYTLDQYVENDYTIVYFHYGLNSRNKPSLGWLQSAYKEFDRKYKKNLKALYVVHPTSFIKVLWNILKPLISHKFGKKVIYFNYLSELHEHLKYDQLVIPPEVLRYDEKLQSLHEGRTPPPTKTPPPRPPLPTQQFGVSLQYLKDKNQGELIPPVLRFTVTYLREKGLRTEGLFRRSASVQTVREIQRLYNQGKPVNFDDYGDIHIPAVILKTFLRELPQPLLTFQAYEQILGITCVESSLRVTGCRQILRSLPEHNYVVLRYLMGFLHAVSRESIFNKMNSSNLACVFGLNLIWPSQGVSSLSALVPLNMFTELLIEYYEKIFSTPEAPGEHGLAPWEQGSRAAPLQEAVPRTQATGLTKPTLPPSPLMAARRRL

Target ORF information:

RefSeq Version	NM_181334.5
Organism	Homo sapiens(human)
Definition	Homo sapiens PRR5-ARHGAP8 readthrough (PRR5-ARHGAP8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_181334.5

ORF Insert Sequence:

ATGAGGACTC TCCGCAGGTT GAAGTTCATG AGTTCGCCCA GCCTCAGTGA CCTGGGCAAG 
AGAGAGCCGG CCGCCGCCGC GGACGAGCGG GGCACGCAGC AGCGCCGGGC CTGCGCCAAC 
GCCACCTGGA ACAGCATCCA CAACGGGGTG ATCGCCGTCT TCCAGCGCAA GGGGCTGCCC 
GACCAGGAGC TCTTCAGCCT CAACGAGGGC GTCCGGCAGC TGTTGAAGAC AGAGCTGGGG 
TCCTTCTTCA CGGAGTACCT GCAGAACCAG CTGCTGACAA AAGGCATGGT GATCCTTCGG 
GACAAGATTC GCTTCTATGA GGAGCTGCAG AGAGACAAGG CGGCGGCGGC TGCTGTGCTG 
GGTGCAGTGA GGAAGAGGCC CTCGGTGGTG CCCATGGCTG GCCAGGATCC TGCGCTGAGC 
ACGAGTCACC CGTTCTACGA CGTGGCCAGA CATGGCATTC TGCAGGTGGC AGGGGATGAC 
CGCTTTGGAA GACGTGTTGT CACGTTCAGC TGCTGCCGGA TGCCACCCTC CCACGAGCTG 
GACCACCAGC GGCTGCTGGA GTATTTGAAG TACACACTGG ACCAATACGT TGAGAACGAT 
TATACCATCG TCTATTTCCA CTACGGGCTG AACAGCCGGA ACAAGCCTTC CCTGGGCTGG 
CTCCAGAGCG CATACAAGGA GTTCGATAGG AAGTACAAGA AGAACTTGAA GGCCCTCTAC 
GTGGTGCACC CCACCAGCTT CATCAAGGTC CTGTGGAACA TCTTGAAGCC CCTCATCAGT 
CACAAGTTTG GGAAGAAAGT CATCTATTTC AACTACCTGA GTGAGCTCCA CGAACACCTT 
AAATACGACC AGCTGGTCAT CCCTCCCGAA GTTTTGCGGT ACGATGAGAA GCTCCAGAGC 
CTGCACGAGG GCCGGACGCC GCCTCCCACC AAGACACCAC CGCCGCGGCC CCCGCTGCCC 
ACACAGCAGT TTGGCGTCAG TCTGCAATAC CTCAAAGACA AAAATCAAGG CGAACTCATC 
CCCCCTGTGC TGAGGTTCAC AGTGACGTAC CTGAGAGAGA AAGGCCTGCG CACCGAGGGC 
CTGTTCCGGA GATCCGCCAG CGTGCAGACC GTCCGCGAGA TCCAGAGGCT CTACAACCAA 
GGGAAGCCCG TGAACTTTGA CGACTACGGG GACATTCACA TCCCTGCCGT GATCCTGAAG 
ACCTTCCTGC GAGAGCTGCC CCAGCCGCTT CTGACCTTCC AGGCCTACGA GCAGATTCTC 
GGGATCACCT GTGTGGAGAG CAGCCTGCGT GTCACTGGCT GCCGCCAGAT CTTACGGAGC 
CTCCCAGAGC ACAACTACGT CGTCCTCCGC TACCTCATGG GCTTCCTGCA TGCGGTGTCC 
CGGGAGAGCA TCTTCAACAA AATGAACAGC TCTAACCTGG CCTGTGTCTT CGGGCTGAAT 
TTGATCTGGC CATCCCAGGG GGTCTCCTCC CTGAGTGCCC TTGTGCCCCT GAACATGTTC 
ACTGAACTGC TGATCGAGTA CTATGAAAAG ATCTTCAGCA CCCCGGAGGC ACCTGGGGAG 
CACGGCCTGG CACCATGGGA ACAGGGGAGC AGGGCAGCCC CTTTGCAGGA GGCTGTGCCA 
CGGACACAAG CCACGGGCCT CACCAAGCCT ACCCTACCTC CGAGTCCCCT GATGGCAGCC 
AGAAGACGTC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Bipolar disorder with comorbid binge eating history: a genome-wide association study implicates APOB.
Journal of affective disorders165151-8(2014 Aug)
Winham SJ,Cuellar-Barboza AB,McElroy SL,Oliveros A,Crow S,Colby CL,Choi DS,Chauhan M,Frye MA,Biernacka JM

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
PloS one5(10)e13284(2010 Oct)
Prakash T,Sharma VK,Adati N,Ozawa R,Kumar N,Nishida Y,Fujikake T,Takeda T,Taylor TD

PRR5 encodes a conserved proline-rich protein predominant in kidney: analysis of genomic organization, expression, and mutation status in breast and colorectal carcinomas.
Genomics85(3)338-51(2005 Mar)
Johnstone CN,Castellv?-Bel S,Chang LM,Sung RK,Bowser MJ,Piqu? JM,Castells A,Rustgi AK

The DNA sequence of human chromosome 22.
Nature402(6761)489-95(1999 Dec)
Dunham I,Shimizu N,Roe BA,Chissoe S,Hunt AR,Collins JE,Bruskiewich R,Beare DM,Clamp M,Smink LJ,Ainscough R,Almeida JP,Babbage A,Bagguley C,Bailey J,Barlow K,Bates KN,Beasley O,Bird CP,Blakey S,Bridgeman AM,Buck D,Burgess J,Burrill WD,O'Brien KP

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PRR5-ARHGAP8 cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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