ERCC6L cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	ERCC6L
Entrez Gene ID	54821
Full Name	ERCC excision repair 6 like, spindle assembly checkpoint helicase
Synonyms	PICH,RAD26L
General protein information	Preferred Names ERCC excision repair 6 like, spindle assembly checkpoint helicase Names DNA excision repair protein ERCC-6-like ATP-dependent helicase ERCC6-like Plk1-interacting checkpoint helicase SNF2/RAD54 family protein excision repair cross-complementation group 6 like excision repair cross-complementing rodent repair deficiency complementation group 6 - like excision repair cross-complementing rodent repair deficiency, complementation group 6-like excision repair protein ERCC6-like tumor antigen BJ-HCC-15
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: X Map Location: Xq13.1
Summary	This gene encodes a member of the SWItch/Sucrose Non-Fermentable (SWI/SNF2) family of proteins, and contains a SNF2-like ATPase domain and a PICH family domain. One distinguishing feature of this SWI/SNF protein family member is that during interphase, the protein is excluded from the nucleus, and only associates with chromatin after the nuclear envelope has broken down. This protein is a DNA translocase that is thought to bind double-stranded DNA that is exposed to stretching forces, such as those exerted by the mitotic spindle. This protein associates with ribosomal DNA and ultra-fine DNA bridges (UFBs), fine structures that connect sister chromatids during anaphase at some sites such as fragile sites, telomeres and centromeres. This gene is required for the faithful segregation of sister chromatids during mitosis, and the ATPase activity of this protein required for the resolution of UFBs before cytokinesis. [provided by RefSeq, May 2017].
Disorder MIM:	300687

mRNA and Protein(s)

mRNA	Protein	Name
NM_017669.3	NP_060139.2	DNA excision repair protein ERCC-6-like isoform a
NM_017669.2	NP_060139.2	DNA excision repair protein ERCC-6-like
NM_017669.4	NP_060139.2	DNA excision repair protein ERCC-6-like isoform a
NM_001009954.2	NP_001009954.1	DNA excision repair protein ERCC-6-like isoform b
NM_001009954.3	NP_001009954.1	DNA excision repair protein ERCC-6-like isoform b

Pathways from BioSystems

Homologies

Bos taurus (cattle)	ERCC6L	NP_001096000.1
Mus musculus (house mouse)	Ercc6l	NP_666347.2
Rattus norvegicus (Norway rat)	Ercc6l	NP_001092144.1
Homo sapiens (human)	ERCC6L	NP_060139.2
Pan troglodytes (chimpanzee)	ERCC6L	XP_003317563.1
	ERCC6L	XP_001092609.1
Xenopus tropicalis (tropical clawed frog)	ercc6l	XP_002936822.1
Canis lupus familiaris (dog)	ERCC6L	XP_549075.3
Gallus gallus (chicken)	ERCC6L	XP_420137.3

Gene Ontology
Bibliography

Related articles in PubMed

A novel TPR-BEN domain interaction mediates PICH-BEND3 association.
Pitchai GP, Kaulich M, Bizard AH, Mesa P, Yao Q, Sarlos K, Streicher WW, Nigg EA, Montoya G, Hickson ID
Nucleic acids research45(19)11413-11424(2017 Nov)

ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers.
Pu SY, Yu Q, Wu H, Jiang JJ, Chen XQ, He YH, Kong QP
Oncotarget8(26)42116-42124(2017 Jun)

Architecture of the human interactome defines protein communities and disease networks.
Huttlin EL, Bruckner RJ, Paulo JA, Cannon JR, Ting L, Baltier K, Colby G, Gebreab F, Gygi MP, Parzen H, Szpyt J, Tam S, Zarraga G, Pontano-Vaites L, Swarup S, White AE, Schweppe DK, Rad R, Erickson BK, Obar RA, Guruharsha KG, Li K, Artavanis-Tsakonas S, Gygi SP, Harper JW
Nature545(7655)505-509(2017 05)

PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction.
Nielsen CF, Hickson ID
Cell cycle (Georgetown, Tex.)15(20)2704-11(2016 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data indicate BEND3 as a new interaction partner for PICH in mitosis, and have defined the residues within a TPR-BEN domain interface that mediate this interaction.
Title: A novel TPR-BEN domain interaction mediates PICH-BEND3 association.

the mitotic roles of PICH and explore further the role of PICH in the timely segregation of the ribosomal DNA locus, are reported.
Title: PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction.

a novel SUMO-dependent regulation of PICH's function on mitotic centromeres, is reported.
Title: SUMO-interacting motifs (SIMs) in Polo-like kinase 1-interacting checkpoint helicase (PICH) ensure proper chromosome segregation during mitosis.

Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex has been reported.
Title: Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex.

PICH and Topo II cooperate to prevent chromosome missegregation events in mitosis.
Title: PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis.

The following ERCC6L gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ERCC6L cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu103066	NM_001009954.3 Latest version!	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	15-17	$559.30 $799.00
OHu09538	NM_017669.4 Latest version!	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$384.30 $549.00
View Old Accession Versions >>
OHu09538	NM_017669.2	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$384.30 $549.00
OHu09538	NM_017669.3	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	16	$384.30 $549.00
OHu103066	NM_001009954.2	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	15-17	$559.30 $799.00
Hide Old Accession Versions >>

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***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ERCC6L ( NM_001009954.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009954.1 Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu103066
Clone ID Related Accession (Same CDS sequence)	NM_001009954.2 , NM_001009954.3
Accession Version	NM_001009954.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-12-16
Organism	Homo sapiens(human)
Product	DNA excision repair protein ERCC-6-like isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB067255.1, AK056494.1 and BC111486.1. This sequence is a reference standard in the RefSeqGene project. On May 27, 2017 this sequence version replaced NM_001009954.1. Transcript Variant: This variant (2) differs in its 5' UTR, resulting in the use of a downstream start codon. Use of the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning results in translation initiation at the downstream start codon to encode an isoform (b) that has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056494.1, DR158316.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGATTAG GGAAGACTGT TCAAATCATT GCTTTCCTTT CCGGTATGTT TGATGCATCA 
CTTGTGAATC ATGTGCTGCT GATCATGCCA ACCAATCTTA TTAACACATG GGTAAAAGAA 
TTCATCAAGT GGACTCCAGG AATGAGAGTC AAAACCTTTC ATGGTCCTAG CAAGGATGAA 
CGGACCAGAA ACCTCAATCG GATTCAGCAA AGGAATGGTG TTATTATCAC TACATACCAA 
ATGTTAATCA ATAACTGGCA GCAACTTTCA AGCTTTAGGG GCCAAGAGTT TGTGTGGGAC 
TATGTCATCC TCGATGAAGC ACATAAAATA AAAACCTCAT CTACTAAGTC AGCAATATGT 
GCTCGTGCTA TTCCTGCAAG TAATCGCCTC CTCCTCACAG GAACCCCAAT CCAGAATAAT 
TTACAAGAAC TATGGTCCCT ATTTGATTTT GCTTGTCAAG GGTCCCTGCT GGGAACATTA 
AAAACTTTTA AGATGGAGTA TGAAAATCCT ATTACTAGAG CAAGAGAGAA GGATGCTACC 
CCAGGAGAAA AAGCCTTGGG ATTTAAAATA TCTGAAAACT TAATGGCAAT CATAAAACCC 
TATTTTCTCA GGAGGACTAA AGAAGACGTA CAGAAGAAAA AGTCAAGCAA CCCAGAGGCC 
AGACTTAATG AAAAGAATCC AGATGTTGAT GCCATTTGTG AAATGCCTTC CCTTTCCAGG 
AAAAATGATT TAATTATTTG GATACGACTT GTGCCTTTAC AAGAAGAAAT ATACAGGAAA 
TTTGTGTCTT TAGATCATAT CAAGGAGTTG CTAATGGAGA CGCGCTCACC TTTGGCTGAG 
CTAGGTGTCT TAAAGAAGCT GTGTGATCAT CCTAGGCTGC TGTCTGCACG GGCTTGTTGT 
TTGCTAAATC TTGGGACATT CTCTGCTCAA GATGGAAATG AGGGGGAAGA TTCCCCAGAT 
GTGGACCATA TTGATCAAGT AACTGATGAC ACATTGATGG AAGAATCTGG AAAAATGATA 
TTCCTAATGG ACCTACTTAA GAGGCTGCGA GATGAGGGAC ATCAAACTCT GGTGTTTTCT 
CAATCGAGGC AAATTCTAAA CATCATTGAA CGCCTCTTAA AGAATAGGCA CTTTAAGACA 
TTGCGAATCG ATGGGACAGT TACTCATCTT TTGGAACGAG AAAAAAGAAT TAACTTATTC 
CAGCAAAATA AAGATTACTC TGTTTTTCTG CTTACCACTC AAGTAGGTGG TGTCGGTTTA 
ACATTAACTG CAGCAACTAG AGTGGTCATT TTTGACCCTA GCTGGAATCC TGCAACTGAT 
GCTCAAGCTG TGGATAGAGT TTACCGAATT GGACAAAAAG AGAATGTTGT GGTTTATAGG 
CTAATCACTT GTGGGACTGT AGAGGAAAAA ATATACAGAA GACAGGTTTT CAAGGACTCA 
TTAATAAGAC AAACTACTGG TGAAAAAAAG AACCCTTTCC GATATTTTAG TAAACAAGAA 
TTAAGAGAGC TCTTTACAAT CGAGGATCTT CAGAACTCTG TAACCCAGCT GCAGCTTCAG 
TCTTTGCATG CTGCTCAGAG GAAATCTGAT ATAAAACTAG ATGAACATAT TGCCTACCTG 
CAGTCTTTGG GGATAGCTGG AATCTCAGAC CATGATTTGA TGTACACATG TGATCTGTCT 
GTTAAAGAAG AGCTTGATGT GGTAGAAGAA TCTCACTATA TTCAACAAAG GGTTCAGAAA 
GCTCAATTCC TCGTTGAATT CGAGTCTCAA AATAAAGAGT TCCTGATGGA ACAACAAAGA 
ACTAGAAATG AGGGGGCCTG GCTAAGAGAA CCTGTATTTC CTTCTTCAAC AAAGAAGAAA 
TGCCCTAAAT TGAATAAACC ACAGCCTCAG CCTTCACCTC TTCTAAGTAC TCATCATACT 
CAGGAAGAAG ATATCAGTTC CAAAATGGCA AGTGTAGTCA TTGATGATCT GCCCAAAGAG 
GGTGAGAAAC AAGATCTCTC CAGTATAAAG GTGAATGTTA CCACCTTGCA AGATGGTAAA 
GGTACAGGTA GTGCTGACTC TATAGCTACT TTACCAAAGG GGTTTGGAAG TGTAGAAGAA 
CTTTGTACTA ACTCTTCATT GGGAATGGAA AAAAGCTTTG CAACTAAAAA TGAAGCTGTA 
CAAAAAGAGA CATTACAAGA GGGGCCTAAG CAAGAGGCAC TGCAAGAGGA TCCTCTGGAA 
AGTTTTAATT ATGTACTTAG CAAATCAACC AAAGCTGATA TTGGGCCAAA TTTAGATCAA 
CTAAAGGATG ATGAGATTTT ACGTCATTGC AATCCTTGGC CCATTATTTC CATAACAAAT 
GAAAGTCAAA ATGCAGAATC AAATGTATCC ATTATTGAAA TAGCTGATGA CCTTTCAGCA 
TCCCATAGTG CACTGCAGGA TGCTCAAGCA AGTGAGGCCA AGTTGGAAGA GGAACCTTCA 
GCATCTTCAC CACAGTATGC ATGTGATTTC AATCTTTTCT TGGAAGACTC AGCAGACAAC 
AGACAAAATT TTTCCAGTCA GTCTTTAGAG CATGTTGAGA AAGAAAATAG CTTGTGTGGC 
TCTGCACCTA ATTCCAGAGC AGGGTTTGTG CATAGCAAAA CATGTCTCAG TTGGGAGTTT 
TCTGAGAAAG ACGATGAACC AGAAGAAGTA GTAGTTAAAG CAAAAATCAG AAGTAAAGCT 
AGAAGGATTG TTTCAGATGG CGAAGATGAA GATGATTCTT TTAAAGATAC CTCAAGCATA 
AATCCATTCA ACACATCTCT CTTTCAATTC TCATCTGTGA AACAATTTGA TGCTTCAACT 
CCCAAAAATG ACATCAGTCC ACCAGGAAGG TTCTTTTCAT CTCAAATACC CAGTAGTGTA 
AATAAGTCTA TGAACTCTAG AAGATCTCTG GCTTCTAGGA GGTCTCTTAT TAATATGGTT 
TTAGACCACG TGGAGGACAT GGAGGAAAGA CTTGACGACA GCAGTGAAGC AAAGGGTCCT 
GAAGATTATC CAGAAGAAGG GGTGGAGGAA AGCAGTGGCG AAGCCTCCAA GTATACAGAA 
GAGGATCCTT CCGGAGAAAC ACTGTCTTCA GAAAACAAGT CCAGCTGGTT AATGACGTCT 
AAGCCTAGTG CTCTAGCTCA AGAGACCTCT CTTGGTGCCC CTGAGCCTTT GTCTGGTGAA 
CAGTTGGTTG GTTCTCCCCA GGATAAGGCG GCAGAGGCTA CAAATGACTA TGAGACTCTT 
GTAAAGCGTG GAAAAGAACT AAAAGAGTGT GGAAAAATCC AGGAGGCCCT AAACTGCTTA 
GTTAAAGCGC TTGACATAAA AAGTGCAGAT CCTGAAGTTA TGCTCTTGAC TTTAAGTTTG 
TATAAGCAAC TTAATAACAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009954.1
CDS	624..4007
Translation	MGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Target ORF information:

RefSeq Version	NM_001009954.2
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009954.2

ORF Insert Sequence:

ATGGGATTAG GGAAGACTGT TCAAATCATT GCTTTCCTTT CCGGTATGTT TGATGCATCA 
CTTGTGAATC ATGTGCTGCT GATCATGCCA ACCAATCTTA TTAACACATG GGTAAAAGAA 
TTCATCAAGT GGACTCCAGG AATGAGAGTC AAAACCTTTC ATGGTCCTAG CAAGGATGAA 
CGGACCAGAA ACCTCAATCG GATTCAGCAA AGGAATGGTG TTATTATCAC TACATACCAA 
ATGTTAATCA ATAACTGGCA GCAACTTTCA AGCTTTAGGG GCCAAGAGTT TGTGTGGGAC 
TATGTCATCC TCGATGAAGC ACATAAAATA AAAACCTCAT CTACTAAGTC AGCAATATGT 
GCTCGTGCTA TTCCTGCAAG TAATCGCCTC CTCCTCACAG GAACCCCAAT CCAGAATAAT 
TTACAAGAAC TATGGTCCCT ATTTGATTTT GCTTGTCAAG GGTCCCTGCT GGGAACATTA 
AAAACTTTTA AGATGGAGTA TGAAAATCCT ATTACTAGAG CAAGAGAGAA GGATGCTACC 
CCAGGAGAAA AAGCCTTGGG ATTTAAAATA TCTGAAAACT TAATGGCAAT CATAAAACCC 
TATTTTCTCA GGAGGACTAA AGAAGACGTA CAGAAGAAAA AGTCAAGCAA CCCAGAGGCC 
AGACTTAATG AAAAGAATCC AGATGTTGAT GCCATTTGTG AAATGCCTTC CCTTTCCAGG 
AAAAATGATT TAATTATTTG GATACGACTT GTGCCTTTAC AAGAAGAAAT ATACAGGAAA 
TTTGTGTCTT TAGATCATAT CAAGGAGTTG CTAATGGAGA CGCGCTCACC TTTGGCTGAG 
CTAGGTGTCT TAAAGAAGCT GTGTGATCAT CCTAGGCTGC TGTCTGCACG GGCTTGTTGT 
TTGCTAAATC TTGGGACATT CTCTGCTCAA GATGGAAATG AGGGGGAAGA TTCCCCAGAT 
GTGGACCATA TTGATCAAGT AACTGATGAC ACATTGATGG AAGAATCTGG AAAAATGATA 
TTCCTAATGG ACCTACTTAA GAGGCTGCGA GATGAGGGAC ATCAAACTCT GGTGTTTTCT 
CAATCGAGGC AAATTCTAAA CATCATTGAA CGCCTCTTAA AGAATAGGCA CTTTAAGACA 
TTGCGAATCG ATGGGACAGT TACTCATCTT TTGGAACGAG AAAAAAGAAT TAACTTATTC 
CAGCAAAATA AAGATTACTC TGTTTTTCTG CTTACCACTC AAGTAGGTGG TGTCGGTTTA 
ACATTAACTG CAGCAACTAG AGTGGTCATT TTTGACCCTA GCTGGAATCC TGCAACTGAT 
GCTCAAGCTG TGGATAGAGT TTACCGAATT GGACAAAAAG AGAATGTTGT GGTTTATAGG 
CTAATCACTT GTGGGACTGT AGAGGAAAAA ATATACAGAA GACAGGTTTT CAAGGACTCA 
TTAATAAGAC AAACTACTGG TGAAAAAAAG AACCCTTTCC GATATTTTAG TAAACAAGAA 
TTAAGAGAGC TCTTTACAAT CGAGGATCTT CAGAACTCTG TAACCCAGCT GCAGCTTCAG 
TCTTTGCATG CTGCTCAGAG GAAATCTGAT ATAAAACTAG ATGAACATAT TGCCTACCTG 
CAGTCTTTGG GGATAGCTGG AATCTCAGAC CATGATTTGA TGTACACATG TGATCTGTCT 
GTTAAAGAAG AGCTTGATGT GGTAGAAGAA TCTCACTATA TTCAACAAAG GGTTCAGAAA 
GCTCAATTCC TCGTTGAATT CGAGTCTCAA AATAAAGAGT TCCTGATGGA ACAACAAAGA 
ACTAGAAATG AGGGGGCCTG GCTAAGAGAA CCTGTATTTC CTTCTTCAAC AAAGAAGAAA 
TGCCCTAAAT TGAATAAACC ACAGCCTCAG CCTTCACCTC TTCTAAGTAC TCATCATACT 
CAGGAAGAAG ATATCAGTTC CAAAATGGCA AGTGTAGTCA TTGATGATCT GCCCAAAGAG 
GGTGAGAAAC AAGATCTCTC CAGTATAAAG GTGAATGTTA CCACCTTGCA AGATGGTAAA 
GGTACAGGTA GTGCTGACTC TATAGCTACT TTACCAAAGG GGTTTGGAAG TGTAGAAGAA 
CTTTGTACTA ACTCTTCATT GGGAATGGAA AAAAGCTTTG CAACTAAAAA TGAAGCTGTA 
CAAAAAGAGA CATTACAAGA GGGGCCTAAG CAAGAGGCAC TGCAAGAGGA TCCTCTGGAA 
AGTTTTAATT ATGTACTTAG CAAATCAACC AAAGCTGATA TTGGGCCAAA TTTAGATCAA 
CTAAAGGATG ATGAGATTTT ACGTCATTGC AATCCTTGGC CCATTATTTC CATAACAAAT 
GAAAGTCAAA ATGCAGAATC AAATGTATCC ATTATTGAAA TAGCTGATGA CCTTTCAGCA 
TCCCATAGTG CACTGCAGGA TGCTCAAGCA AGTGAGGCCA AGTTGGAAGA GGAACCTTCA 
GCATCTTCAC CACAGTATGC ATGTGATTTC AATCTTTTCT TGGAAGACTC AGCAGACAAC 
AGACAAAATT TTTCCAGTCA GTCTTTAGAG CATGTTGAGA AAGAAAATAG CTTGTGTGGC 
TCTGCACCTA ATTCCAGAGC AGGGTTTGTG CATAGCAAAA CATGTCTCAG TTGGGAGTTT 
TCTGAGAAAG ACGATGAACC AGAAGAAGTA GTAGTTAAAG CAAAAATCAG AAGTAAAGCT 
AGAAGGATTG TTTCAGATGG CGAAGATGAA GATGATTCTT TTAAAGATAC CTCAAGCATA 
AATCCATTCA ACACATCTCT CTTTCAATTC TCATCTGTGA AACAATTTGA TGCTTCAACT 
CCCAAAAATG ACATCAGTCC ACCAGGAAGG TTCTTTTCAT CTCAAATACC CAGTAGTGTA 
AATAAGTCTA TGAACTCTAG AAGATCTCTG GCTTCTAGGA GGTCTCTTAT TAATATGGTT 
TTAGACCACG TGGAGGACAT GGAGGAAAGA CTTGACGACA GCAGTGAAGC AAAGGGTCCT 
GAAGATTATC CAGAAGAAGG GGTGGAGGAA AGCAGTGGCG AAGCCTCCAA GTATACAGAA 
GAGGATCCTT CCGGAGAAAC ACTGTCTTCA GAAAACAAGT CCAGCTGGTT AATGACGTCT 
AAGCCTAGTG CTCTAGCTCA AGAGACCTCT CTTGGTGCCC CTGAGCCTTT GTCTGGTGAA 
CAGTTGGTTG GTTCTCCCCA GGATAAGGCG GCAGAGGCTA CAAATGACTA TGAGACTCTT 
GTAAAGCGTG GAAAAGAACT AAAAGAGTGT GGAAAAATCC AGGAGGCCCT AAACTGCTTA 
GTTAAAGCGC TTGACATAAA AAGTGCAGAT CCTGAAGTTA TGCTCTTGAC TTTAAGTTTG 
TATAAGCAAC TTAATAACAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERCC6L ( NM_001009954.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_001009954.1 Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu103066
Clone ID Related Accession (Same CDS sequence)	NM_001009954.2 , NM_001009954.3
Accession Version	NM_001009954.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3384bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-09
Organism	Homo sapiens(human)
Product	DNA excision repair protein ERCC-6-like isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK056494.1 and BC111486.1. This sequence is a reference standard in the RefSeqGene project. On May 31, 2019 this sequence version replaced NM_001009954.2. Transcript Variant: This variant (2) differs in its 5' UTR, resulting in the use of a downstream start codon. Use of the 5'-most initiation codon, as used in variant 1, is associated with a truncated ORF that would render the transcript a candidate for nonsense-mediated decay (NMD). Leaky scanning results in translation initiation at the downstream start codon to encode an isoform (b) that has a shorter N-terminus, compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK056494.1, DR158316.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGGATTAG GGAAGACTGT TCAAATCATT GCTTTCCTTT CCGGTATGTT TGATGCATCA 
CTTGTGAATC ATGTGCTGCT GATCATGCCA ACCAATCTTA TTAACACATG GGTAAAAGAA 
TTCATCAAGT GGACTCCAGG AATGAGAGTC AAAACCTTTC ATGGTCCTAG CAAGGATGAA 
CGGACCAGAA ACCTCAATCG GATTCAGCAA AGGAATGGTG TTATTATCAC TACATACCAA 
ATGTTAATCA ATAACTGGCA GCAACTTTCA AGCTTTAGGG GCCAAGAGTT TGTGTGGGAC 
TATGTCATCC TCGATGAAGC ACATAAAATA AAAACCTCAT CTACTAAGTC AGCAATATGT 
GCTCGTGCTA TTCCTGCAAG TAATCGCCTC CTCCTCACAG GAACCCCAAT CCAGAATAAT 
TTACAAGAAC TATGGTCCCT ATTTGATTTT GCTTGTCAAG GGTCCCTGCT GGGAACATTA 
AAAACTTTTA AGATGGAGTA TGAAAATCCT ATTACTAGAG CAAGAGAGAA GGATGCTACC 
CCAGGAGAAA AAGCCTTGGG ATTTAAAATA TCTGAAAACT TAATGGCAAT CATAAAACCC 
TATTTTCTCA GGAGGACTAA AGAAGACGTA CAGAAGAAAA AGTCAAGCAA CCCAGAGGCC 
AGACTTAATG AAAAGAATCC AGATGTTGAT GCCATTTGTG AAATGCCTTC CCTTTCCAGG 
AAAAATGATT TAATTATTTG GATACGACTT GTGCCTTTAC AAGAAGAAAT ATACAGGAAA 
TTTGTGTCTT TAGATCATAT CAAGGAGTTG CTAATGGAGA CGCGCTCACC TTTGGCTGAG 
CTAGGTGTCT TAAAGAAGCT GTGTGATCAT CCTAGGCTGC TGTCTGCACG GGCTTGTTGT 
TTGCTAAATC TTGGGACATT CTCTGCTCAA GATGGAAATG AGGGGGAAGA TTCCCCAGAT 
GTGGACCATA TTGATCAAGT AACTGATGAC ACATTGATGG AAGAATCTGG AAAAATGATA 
TTCCTAATGG ACCTACTTAA GAGGCTGCGA GATGAGGGAC ATCAAACTCT GGTGTTTTCT 
CAATCGAGGC AAATTCTAAA CATCATTGAA CGCCTCTTAA AGAATAGGCA CTTTAAGACA 
TTGCGAATCG ATGGGACAGT TACTCATCTT TTGGAACGAG AAAAAAGAAT TAACTTATTC 
CAGCAAAATA AAGATTACTC TGTTTTTCTG CTTACCACTC AAGTAGGTGG TGTCGGTTTA 
ACATTAACTG CAGCAACTAG AGTGGTCATT TTTGACCCTA GCTGGAATCC TGCAACTGAT 
GCTCAAGCTG TGGATAGAGT TTACCGAATT GGACAAAAAG AGAATGTTGT GGTTTATAGG 
CTAATCACTT GTGGGACTGT AGAGGAAAAA ATATACAGAA GACAGGTTTT CAAGGACTCA 
TTAATAAGAC AAACTACTGG TGAAAAAAAG AACCCTTTCC GATATTTTAG TAAACAAGAA 
TTAAGAGAGC TCTTTACAAT CGAGGATCTT CAGAACTCTG TAACCCAGCT GCAGCTTCAG 
TCTTTGCATG CTGCTCAGAG GAAATCTGAT ATAAAACTAG ATGAACATAT TGCCTACCTG 
CAGTCTTTGG GGATAGCTGG AATCTCAGAC CATGATTTGA TGTACACATG TGATCTGTCT 
GTTAAAGAAG AGCTTGATGT GGTAGAAGAA TCTCACTATA TTCAACAAAG GGTTCAGAAA 
GCTCAATTCC TCGTTGAATT CGAGTCTCAA AATAAAGAGT TCCTGATGGA ACAACAAAGA 
ACTAGAAATG AGGGGGCCTG GCTAAGAGAA CCTGTATTTC CTTCTTCAAC AAAGAAGAAA 
TGCCCTAAAT TGAATAAACC ACAGCCTCAG CCTTCACCTC TTCTAAGTAC TCATCATACT 
CAGGAAGAAG ATATCAGTTC CAAAATGGCA AGTGTAGTCA TTGATGATCT GCCCAAAGAG 
GGTGAGAAAC AAGATCTCTC CAGTATAAAG GTGAATGTTA CCACCTTGCA AGATGGTAAA 
GGTACAGGTA GTGCTGACTC TATAGCTACT TTACCAAAGG GGTTTGGAAG TGTAGAAGAA 
CTTTGTACTA ACTCTTCATT GGGAATGGAA AAAAGCTTTG CAACTAAAAA TGAAGCTGTA 
CAAAAAGAGA CATTACAAGA GGGGCCTAAG CAAGAGGCAC TGCAAGAGGA TCCTCTGGAA 
AGTTTTAATT ATGTACTTAG CAAATCAACC AAAGCTGATA TTGGGCCAAA TTTAGATCAA 
CTAAAGGATG ATGAGATTTT ACGTCATTGC AATCCTTGGC CCATTATTTC CATAACAAAT 
GAAAGTCAAA ATGCAGAATC AAATGTATCC ATTATTGAAA TAGCTGATGA CCTTTCAGCA 
TCCCATAGTG CACTGCAGGA TGCTCAAGCA AGTGAGGCCA AGTTGGAAGA GGAACCTTCA 
GCATCTTCAC CACAGTATGC ATGTGATTTC AATCTTTTCT TGGAAGACTC AGCAGACAAC 
AGACAAAATT TTTCCAGTCA GTCTTTAGAG CATGTTGAGA AAGAAAATAG CTTGTGTGGC 
TCTGCACCTA ATTCCAGAGC AGGGTTTGTG CATAGCAAAA CATGTCTCAG TTGGGAGTTT 
TCTGAGAAAG ACGATGAACC AGAAGAAGTA GTAGTTAAAG CAAAAATCAG AAGTAAAGCT 
AGAAGGATTG TTTCAGATGG CGAAGATGAA GATGATTCTT TTAAAGATAC CTCAAGCATA 
AATCCATTCA ACACATCTCT CTTTCAATTC TCATCTGTGA AACAATTTGA TGCTTCAACT 
CCCAAAAATG ACATCAGTCC ACCAGGAAGG TTCTTTTCAT CTCAAATACC CAGTAGTGTA 
AATAAGTCTA TGAACTCTAG AAGATCTCTG GCTTCTAGGA GGTCTCTTAT TAATATGGTT 
TTAGACCACG TGGAGGACAT GGAGGAAAGA CTTGACGACA GCAGTGAAGC AAAGGGTCCT 
GAAGATTATC CAGAAGAAGG GGTGGAGGAA AGCAGTGGCG AAGCCTCCAA GTATACAGAA 
GAGGATCCTT CCGGAGAAAC ACTGTCTTCA GAAAACAAGT CCAGCTGGTT AATGACGTCT 
AAGCCTAGTG CTCTAGCTCA AGAGACCTCT CTTGGTGCCC CTGAGCCTTT GTCTGGTGAA 
CAGTTGGTTG GTTCTCCCCA GGATAAGGCG GCAGAGGCTA CAAATGACTA TGAGACTCTT 
GTAAAGCGTG GAAAAGAACT AAAAGAGTGT GGAAAAATCC AGGAGGCCCT AAACTGCTTA 
GTTAAAGCGC TTGACATAAA AAGTGCAGAT CCTGAAGTTA TGCTCTTGAC TTTAAGTTTG 
TATAAGCAAC TTAATAACAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001009954.1
CDS	604..3987
Translation	MGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Target ORF information:

RefSeq Version	NM_001009954.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001009954.3

ORF Insert Sequence:

ATGGGATTAG GGAAGACTGT TCAAATCATT GCTTTCCTTT CCGGTATGTT TGATGCATCA 
CTTGTGAATC ATGTGCTGCT GATCATGCCA ACCAATCTTA TTAACACATG GGTAAAAGAA 
TTCATCAAGT GGACTCCAGG AATGAGAGTC AAAACCTTTC ATGGTCCTAG CAAGGATGAA 
CGGACCAGAA ACCTCAATCG GATTCAGCAA AGGAATGGTG TTATTATCAC TACATACCAA 
ATGTTAATCA ATAACTGGCA GCAACTTTCA AGCTTTAGGG GCCAAGAGTT TGTGTGGGAC 
TATGTCATCC TCGATGAAGC ACATAAAATA AAAACCTCAT CTACTAAGTC AGCAATATGT 
GCTCGTGCTA TTCCTGCAAG TAATCGCCTC CTCCTCACAG GAACCCCAAT CCAGAATAAT 
TTACAAGAAC TATGGTCCCT ATTTGATTTT GCTTGTCAAG GGTCCCTGCT GGGAACATTA 
AAAACTTTTA AGATGGAGTA TGAAAATCCT ATTACTAGAG CAAGAGAGAA GGATGCTACC 
CCAGGAGAAA AAGCCTTGGG ATTTAAAATA TCTGAAAACT TAATGGCAAT CATAAAACCC 
TATTTTCTCA GGAGGACTAA AGAAGACGTA CAGAAGAAAA AGTCAAGCAA CCCAGAGGCC 
AGACTTAATG AAAAGAATCC AGATGTTGAT GCCATTTGTG AAATGCCTTC CCTTTCCAGG 
AAAAATGATT TAATTATTTG GATACGACTT GTGCCTTTAC AAGAAGAAAT ATACAGGAAA 
TTTGTGTCTT TAGATCATAT CAAGGAGTTG CTAATGGAGA CGCGCTCACC TTTGGCTGAG 
CTAGGTGTCT TAAAGAAGCT GTGTGATCAT CCTAGGCTGC TGTCTGCACG GGCTTGTTGT 
TTGCTAAATC TTGGGACATT CTCTGCTCAA GATGGAAATG AGGGGGAAGA TTCCCCAGAT 
GTGGACCATA TTGATCAAGT AACTGATGAC ACATTGATGG AAGAATCTGG AAAAATGATA 
TTCCTAATGG ACCTACTTAA GAGGCTGCGA GATGAGGGAC ATCAAACTCT GGTGTTTTCT 
CAATCGAGGC AAATTCTAAA CATCATTGAA CGCCTCTTAA AGAATAGGCA CTTTAAGACA 
TTGCGAATCG ATGGGACAGT TACTCATCTT TTGGAACGAG AAAAAAGAAT TAACTTATTC 
CAGCAAAATA AAGATTACTC TGTTTTTCTG CTTACCACTC AAGTAGGTGG TGTCGGTTTA 
ACATTAACTG CAGCAACTAG AGTGGTCATT TTTGACCCTA GCTGGAATCC TGCAACTGAT 
GCTCAAGCTG TGGATAGAGT TTACCGAATT GGACAAAAAG AGAATGTTGT GGTTTATAGG 
CTAATCACTT GTGGGACTGT AGAGGAAAAA ATATACAGAA GACAGGTTTT CAAGGACTCA 
TTAATAAGAC AAACTACTGG TGAAAAAAAG AACCCTTTCC GATATTTTAG TAAACAAGAA 
TTAAGAGAGC TCTTTACAAT CGAGGATCTT CAGAACTCTG TAACCCAGCT GCAGCTTCAG 
TCTTTGCATG CTGCTCAGAG GAAATCTGAT ATAAAACTAG ATGAACATAT TGCCTACCTG 
CAGTCTTTGG GGATAGCTGG AATCTCAGAC CATGATTTGA TGTACACATG TGATCTGTCT 
GTTAAAGAAG AGCTTGATGT GGTAGAAGAA TCTCACTATA TTCAACAAAG GGTTCAGAAA 
GCTCAATTCC TCGTTGAATT CGAGTCTCAA AATAAAGAGT TCCTGATGGA ACAACAAAGA 
ACTAGAAATG AGGGGGCCTG GCTAAGAGAA CCTGTATTTC CTTCTTCAAC AAAGAAGAAA 
TGCCCTAAAT TGAATAAACC ACAGCCTCAG CCTTCACCTC TTCTAAGTAC TCATCATACT 
CAGGAAGAAG ATATCAGTTC CAAAATGGCA AGTGTAGTCA TTGATGATCT GCCCAAAGAG 
GGTGAGAAAC AAGATCTCTC CAGTATAAAG GTGAATGTTA CCACCTTGCA AGATGGTAAA 
GGTACAGGTA GTGCTGACTC TATAGCTACT TTACCAAAGG GGTTTGGAAG TGTAGAAGAA 
CTTTGTACTA ACTCTTCATT GGGAATGGAA AAAAGCTTTG CAACTAAAAA TGAAGCTGTA 
CAAAAAGAGA CATTACAAGA GGGGCCTAAG CAAGAGGCAC TGCAAGAGGA TCCTCTGGAA 
AGTTTTAATT ATGTACTTAG CAAATCAACC AAAGCTGATA TTGGGCCAAA TTTAGATCAA 
CTAAAGGATG ATGAGATTTT ACGTCATTGC AATCCTTGGC CCATTATTTC CATAACAAAT 
GAAAGTCAAA ATGCAGAATC AAATGTATCC ATTATTGAAA TAGCTGATGA CCTTTCAGCA 
TCCCATAGTG CACTGCAGGA TGCTCAAGCA AGTGAGGCCA AGTTGGAAGA GGAACCTTCA 
GCATCTTCAC CACAGTATGC ATGTGATTTC AATCTTTTCT TGGAAGACTC AGCAGACAAC 
AGACAAAATT TTTCCAGTCA GTCTTTAGAG CATGTTGAGA AAGAAAATAG CTTGTGTGGC 
TCTGCACCTA ATTCCAGAGC AGGGTTTGTG CATAGCAAAA CATGTCTCAG TTGGGAGTTT 
TCTGAGAAAG ACGATGAACC AGAAGAAGTA GTAGTTAAAG CAAAAATCAG AAGTAAAGCT 
AGAAGGATTG TTTCAGATGG CGAAGATGAA GATGATTCTT TTAAAGATAC CTCAAGCATA 
AATCCATTCA ACACATCTCT CTTTCAATTC TCATCTGTGA AACAATTTGA TGCTTCAACT 
CCCAAAAATG ACATCAGTCC ACCAGGAAGG TTCTTTTCAT CTCAAATACC CAGTAGTGTA 
AATAAGTCTA TGAACTCTAG AAGATCTCTG GCTTCTAGGA GGTCTCTTAT TAATATGGTT 
TTAGACCACG TGGAGGACAT GGAGGAAAGA CTTGACGACA GCAGTGAAGC AAAGGGTCCT 
GAAGATTATC CAGAAGAAGG GGTGGAGGAA AGCAGTGGCG AAGCCTCCAA GTATACAGAA 
GAGGATCCTT CCGGAGAAAC ACTGTCTTCA GAAAACAAGT CCAGCTGGTT AATGACGTCT 
AAGCCTAGTG CTCTAGCTCA AGAGACCTCT CTTGGTGCCC CTGAGCCTTT GTCTGGTGAA 
CAGTTGGTTG GTTCTCCCCA GGATAAGGCG GCAGAGGCTA CAAATGACTA TGAGACTCTT 
GTAAAGCGTG GAAAAGAACT AAAAGAGTGT GGAAAAATCC AGGAGGCCCT AAACTGCTTA 
GTTAAAGCGC TTGACATAAA AAGTGCAGAT CCTGAAGTTA TGCTCTTGAC TTTAAGTTTG 
TATAAGCAAC TTAATAACAA TTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERCC6L ( NM_017669.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060139.2 Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.

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CloneID	OHu09538
Clone ID Related Accession (Same CDS sequence)	NM_017669.3 , NM_017669.2 , NM_017669.4
Accession Version	NM_017669.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	DNA excision repair protein ERCC-6-like isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB067255.1 and BC111486.1. On May 27, 2017 this sequence version replaced NM_017669.2. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC111486.1, EU069463.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060139.2
CDS	137..3889
Translation	MEASRRFPEAEALSPEQAAHYLRYVKEAKEATKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQGDDEFTDVCNSGLLLYRELHNQLFEHQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Target ORF information:

RefSeq Version	NM_017669.3
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017669.3

ORF Insert Sequence:

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERCC6L ( NM_017669.2 ) cDNA ORF clone, Homo sapiens(human) -> NP_060139.2 Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), mRNA.

Price & Availability↑

CloneID	OHu09538
Clone ID Related Accession (Same CDS sequence)	NM_017669.3 , NM_017669.2 , NM_017669.4
Accession Version	NM_017669.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-04-26
Organism	Homo sapiens(Human)
Product	DNA excision repair protein ERCC-6-like
Comment	VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BU431499.1, BM454829.1, AK074719.1, BC008808.2 and AW015865.1. On Jan 29, 2005 this sequence version replaced NM_017669.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.272015.1, BC111486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060139.2
CDS	98..3850
Translation	MEASRRFPEAEALSPEQAAHYLRYVKEAKEATKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQGDDEFTDVCNSGLLLYRELHNQLFEHQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Target ORF information:

RefSeq Version	NM_017669.2
Organism	Homo sapiens(Human)
Definition	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017669.2

ORF Insert Sequence:

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

ERCC6L ( NM_017669.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060139.2 Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu09538
Clone ID Related Accession (Same CDS sequence)	NM_017669.3 , NM_017669.2 , NM_017669.4
Accession Version	NM_017669.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3753bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-10
Organism	Homo sapiens(human)
Product	DNA excision repair protein ERCC-6-like isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB067255.1 and BC111486.1. On Nov 23, 2018 this sequence version replaced NM_017669.3. Transcript Variant: This variant (1) encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC111486.1, EU069463.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000334463.4/ ENSP00000334675.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060139.2
CDS	117..3869
Translation	MEASRRFPEAEALSPEQAAHYLRYVKEAKEATKNGDLEEAFKLFNLAKDIFPNEKVLSRIQKIQEALEELAEQGDDEFTDVCNSGLLLYRELHNQLFEHQKEGIAFLYSLYRDGRKGGILADDMGLGKTVQIIAFLSGMFDASLVNHVLLIMPTNLINTWVKEFIKWTPGMRVKTFHGPSKDERTRNLNRIQQRNGVIITTYQMLINNWQQLSSFRGQEFVWDYVILDEAHKIKTSSTKSAICARAIPASNRLLLTGTPIQNNLQELWSLFDFACQGSLLGTLKTFKMEYENPITRAREKDATPGEKALGFKISENLMAIIKPYFLRRTKEDVQKKKSSNPEARLNEKNPDVDAICEMPSLSRKNDLIIWIRLVPLQEEIYRKFVSLDHIKELLMETRSPLAELGVLKKLCDHPRLLSARACCLLNLGTFSAQDGNEGEDSPDVDHIDQVTDDTLMEESGKMIFLMDLLKRLRDEGHQTLVFSQSRQILNIIERLLKNRHFKTLRIDGTVTHLLEREKRINLFQQNKDYSVFLLTTQVGGVGLTLTAATRVVIFDPSWNPATDAQAVDRVYRIGQKENVVVYRLITCGTVEEKIYRRQVFKDSLIRQTTGEKKNPFRYFSKQELRELFTIEDLQNSVTQLQLQSLHAAQRKSDIKLDEHIAYLQSLGIAGISDHDLMYTCDLSVKEELDVVEESHYIQQRVQKAQFLVEFESQNKEFLMEQQRTRNEGAWLREPVFPSSTKKKCPKLNKPQPQPSPLLSTHHTQEEDISSKMASVVIDDLPKEGEKQDLSSIKVNVTTLQDGKGTGSADSIATLPKGFGSVEELCTNSSLGMEKSFATKNEAVQKETLQEGPKQEALQEDPLESFNYVLSKSTKADIGPNLDQLKDDEILRHCNPWPIISITNESQNAESNVSIIEIADDLSASHSALQDAQASEAKLEEEPSASSPQYACDFNLFLEDSADNRQNFSSQSLEHVEKENSLCGSAPNSRAGFVHSKTCLSWEFSEKDDEPEEVVVKAKIRSKARRIVSDGEDEDDSFKDTSSINPFNTSLFQFSSVKQFDASTPKNDISPPGRFFSSQIPSSVNKSMNSRRSLASRRSLINMVLDHVEDMEERLDDSSEAKGPEDYPEEGVEESSGEASKYTEEDPSGETLSSENKSSWLMTSKPSALAQETSLGAPEPLSGEQLVGSPQDKAAEATNDYETLVKRGKELKECGKIQEALNCLVKALDIKSADPEVMLLTLSLYKQLNNN

Target ORF information:

RefSeq Version	NM_017669.4
Organism	Homo sapiens(human)
Definition	Homo sapiens ERCC excision repair 6 like, spindle assembly checkpoint helicase (ERCC6L), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017669.4

ORF Insert Sequence:

ATGGAGGCAT CCCGAAGGTT TCCGGAAGCC GAGGCCTTGA GCCCAGAGCA GGCTGCTCAT 
TACCTAAGAT ATGTGAAAGA GGCCAAAGAA GCAACTAAGA ATGGAGACCT GGAAGAAGCA 
TTTAAACTTT TCAATTTGGC AAAGGACATT TTTCCCAATG AAAAAGTGCT GAGCAGAATC 
CAAAAAATAC AGGAAGCCTT GGAGGAGTTG GCAGAACAGG GAGATGATGA ATTTACAGAT 
GTGTGCAACT CTGGCTTGCT ACTTTATCGA GAACTGCACA ACCAACTCTT TGAGCACCAG 
AAGGAAGGCA TAGCTTTCCT CTATAGCCTG TATAGGGATG GAAGAAAAGG TGGTATATTG 
GCTGATGATA TGGGATTAGG GAAGACTGTT CAAATCATTG CTTTCCTTTC CGGTATGTTT 
GATGCATCAC TTGTGAATCA TGTGCTGCTG ATCATGCCAA CCAATCTTAT TAACACATGG 
GTAAAAGAAT TCATCAAGTG GACTCCAGGA ATGAGAGTCA AAACCTTTCA TGGTCCTAGC 
AAGGATGAAC GGACCAGAAA CCTCAATCGG ATTCAGCAAA GGAATGGTGT TATTATCACT 
ACATACCAAA TGTTAATCAA TAACTGGCAG CAACTTTCAA GCTTTAGGGG CCAAGAGTTT 
GTGTGGGACT ATGTCATCCT CGATGAAGCA CATAAAATAA AAACCTCATC TACTAAGTCA 
GCAATATGTG CTCGTGCTAT TCCTGCAAGT AATCGCCTCC TCCTCACAGG AACCCCAATC 
CAGAATAATT TACAAGAACT ATGGTCCCTA TTTGATTTTG CTTGTCAAGG GTCCCTGCTG 
GGAACATTAA AAACTTTTAA GATGGAGTAT GAAAATCCTA TTACTAGAGC AAGAGAGAAG 
GATGCTACCC CAGGAGAAAA AGCCTTGGGA TTTAAAATAT CTGAAAACTT AATGGCAATC 
ATAAAACCCT ATTTTCTCAG GAGGACTAAA GAAGACGTAC AGAAGAAAAA GTCAAGCAAC 
CCAGAGGCCA GACTTAATGA AAAGAATCCA GATGTTGATG CCATTTGTGA AATGCCTTCC 
CTTTCCAGGA AAAATGATTT AATTATTTGG ATACGACTTG TGCCTTTACA AGAAGAAATA 
TACAGGAAAT TTGTGTCTTT AGATCATATC AAGGAGTTGC TAATGGAGAC GCGCTCACCT 
TTGGCTGAGC TAGGTGTCTT AAAGAAGCTG TGTGATCATC CTAGGCTGCT GTCTGCACGG 
GCTTGTTGTT TGCTAAATCT TGGGACATTC TCTGCTCAAG ATGGAAATGA GGGGGAAGAT 
TCCCCAGATG TGGACCATAT TGATCAAGTA ACTGATGACA CATTGATGGA AGAATCTGGA 
AAAATGATAT TCCTAATGGA CCTACTTAAG AGGCTGCGAG ATGAGGGACA TCAAACTCTG 
GTGTTTTCTC AATCGAGGCA AATTCTAAAC ATCATTGAAC GCCTCTTAAA GAATAGGCAC 
TTTAAGACAT TGCGAATCGA TGGGACAGTT ACTCATCTTT TGGAACGAGA AAAAAGAATT 
AACTTATTCC AGCAAAATAA AGATTACTCT GTTTTTCTGC TTACCACTCA AGTAGGTGGT 
GTCGGTTTAA CATTAACTGC AGCAACTAGA GTGGTCATTT TTGACCCTAG CTGGAATCCT 
GCAACTGATG CTCAAGCTGT GGATAGAGTT TACCGAATTG GACAAAAAGA GAATGTTGTG 
GTTTATAGGC TAATCACTTG TGGGACTGTA GAGGAAAAAA TATACAGAAG ACAGGTTTTC 
AAGGACTCAT TAATAAGACA AACTACTGGT GAAAAAAAGA ACCCTTTCCG ATATTTTAGT 
AAACAAGAAT TAAGAGAGCT CTTTACAATC GAGGATCTTC AGAACTCTGT AACCCAGCTG 
CAGCTTCAGT CTTTGCATGC TGCTCAGAGG AAATCTGATA TAAAACTAGA TGAACATATT 
GCCTACCTGC AGTCTTTGGG GATAGCTGGA ATCTCAGACC ATGATTTGAT GTACACATGT 
GATCTGTCTG TTAAAGAAGA GCTTGATGTG GTAGAAGAAT CTCACTATAT TCAACAAAGG 
GTTCAGAAAG CTCAATTCCT CGTTGAATTC GAGTCTCAAA ATAAAGAGTT CCTGATGGAA 
CAACAAAGAA CTAGAAATGA GGGGGCCTGG CTAAGAGAAC CTGTATTTCC TTCTTCAACA 
AAGAAGAAAT GCCCTAAATT GAATAAACCA CAGCCTCAGC CTTCACCTCT TCTAAGTACT 
CATCATACTC AGGAAGAAGA TATCAGTTCC AAAATGGCAA GTGTAGTCAT TGATGATCTG 
CCCAAAGAGG GTGAGAAACA AGATCTCTCC AGTATAAAGG TGAATGTTAC CACCTTGCAA 
GATGGTAAAG GTACAGGTAG TGCTGACTCT ATAGCTACTT TACCAAAGGG GTTTGGAAGT 
GTAGAAGAAC TTTGTACTAA CTCTTCATTG GGAATGGAAA AAAGCTTTGC AACTAAAAAT 
GAAGCTGTAC AAAAAGAGAC ATTACAAGAG GGGCCTAAGC AAGAGGCACT GCAAGAGGAT 
CCTCTGGAAA GTTTTAATTA TGTACTTAGC AAATCAACCA AAGCTGATAT TGGGCCAAAT 
TTAGATCAAC TAAAGGATGA TGAGATTTTA CGTCATTGCA ATCCTTGGCC CATTATTTCC 
ATAACAAATG AAAGTCAAAA TGCAGAATCA AATGTATCCA TTATTGAAAT AGCTGATGAC 
CTTTCAGCAT CCCATAGTGC ACTGCAGGAT GCTCAAGCAA GTGAGGCCAA GTTGGAAGAG 
GAACCTTCAG CATCTTCACC ACAGTATGCA TGTGATTTCA ATCTTTTCTT GGAAGACTCA 
GCAGACAACA GACAAAATTT TTCCAGTCAG TCTTTAGAGC ATGTTGAGAA AGAAAATAGC 
TTGTGTGGCT CTGCACCTAA TTCCAGAGCA GGGTTTGTGC ATAGCAAAAC ATGTCTCAGT 
TGGGAGTTTT CTGAGAAAGA CGATGAACCA GAAGAAGTAG TAGTTAAAGC AAAAATCAGA 
AGTAAAGCTA GAAGGATTGT TTCAGATGGC GAAGATGAAG ATGATTCTTT TAAAGATACC 
TCAAGCATAA ATCCATTCAA CACATCTCTC TTTCAATTCT CATCTGTGAA ACAATTTGAT 
GCTTCAACTC CCAAAAATGA CATCAGTCCA CCAGGAAGGT TCTTTTCATC TCAAATACCC 
AGTAGTGTAA ATAAGTCTAT GAACTCTAGA AGATCTCTGG CTTCTAGGAG GTCTCTTATT 
AATATGGTTT TAGACCACGT GGAGGACATG GAGGAAAGAC TTGACGACAG CAGTGAAGCA 
AAGGGTCCTG AAGATTATCC AGAAGAAGGG GTGGAGGAAA GCAGTGGCGA AGCCTCCAAG 
TATACAGAAG AGGATCCTTC CGGAGAAACA CTGTCTTCAG AAAACAAGTC CAGCTGGTTA 
ATGACGTCTA AGCCTAGTGC TCTAGCTCAA GAGACCTCTC TTGGTGCCCC TGAGCCTTTG 
TCTGGTGAAC AGTTGGTTGG TTCTCCCCAG GATAAGGCGG CAGAGGCTAC AAATGACTAT 
GAGACTCTTG TAAAGCGTGG AAAAGAACTA AAAGAGTGTG GAAAAATCCA GGAGGCCCTA 
AACTGCTTAG TTAAAGCGCT TGACATAAAA AGTGCAGATC CTGAAGTTAT GCTCTTGACT 
TTAAGTTTGT ATAAGCAACT TAATAACAAT TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A novel TPR-BEN domain interaction mediates PICH-BEND3 association.
Nucleic acids research45(19)11413-11424(2017 Nov)
Pitchai GP,Kaulich M,Bizard AH,Mesa P,Yao Q,Sarlos K,Streicher WW,Nigg EA,Montoya G,Hickson ID

ERCC6L, a DNA helicase, is involved in cell proliferation and associated with survival and progress in breast and kidney cancers.
Oncotarget8(26)42116-42124(2017 Jun)
Pu SY,Yu Q,Wu H,Jiang JJ,Chen XQ,He YH,Kong QP

Architecture of the human interactome defines protein communities and disease networks.
Nature545(7655)505-509(2017 05)
Huttlin EL,Bruckner RJ,Paulo JA,Cannon JR,Ting L,Baltier K,Colby G,Gebreab F,Gygi MP,Parzen H,Szpyt J,Tam S,Zarraga G,Pontano-Vaites L,Swarup S,White AE,Schweppe DK,Rad R,Erickson BK,Obar RA,Guruharsha KG,Li K,Artavanis-Tsakonas S,Gygi SP,Harper JW

PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction.
Cell cycle (Georgetown, Tex.)15(20)2704-11(2016 Oct)
Nielsen CF,Hickson ID

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ERCC6L cDNA ORF clone, Homo sapiens(human)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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